Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart

Circulation

Volumn 108, Issue 8, 2003, Pages 1022-1026

  Bekeredjian, Raffi ^a   Chen, Shuyuan ^c   Frenkel, Peter A ^b   Grayburn, Paul A ^c   Shohet, Ralph V ^a,d  

^a Department of Internal Medicine ^*  (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Contrast media; Echocardiography; Gene therapy; Ultrasonics

Indexed keywords

ALBUMIN; LIPID; MESSENGER RNA; PLASMID VECTOR; VIRUS VECTOR;

ANIMAL TISSUE; ARTICLE; BUBBLE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; GENE EXPRESSION; GENE THERAPY; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; REPORTER GENE; TRANSGENE; ULTRASOUND;

ANIMALS; CONTRAST MEDIA; CYTOMEGALOVIRUS; GENE EXPRESSION; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; HEART; LUCIFERASES; MICROSPHERES; MYOCARDIUM; ORGAN SPECIFICITY; PLASMIDS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TIME FACTORS; TRANSGENES; ULTRASONIC THERAPY;

EID: 0041857832     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000084535.35435.AE     Document Type: Article

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