Applications of structure-based design to antibacterial drug discovery

Bioorganic Chemistry

Volumn 55, Issue , 2014, Pages 69-76

  Cain, Ricky ^a   Narramore, Sarah ^a   McPhillie, Martin ^a   Simmons, Katie ^a   Fishwick, Colin W G ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Antibacterial agents; Structure based drug design

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL RNA; PYRUVATE KINASE;

ALGORITHM; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BINDING AFFINITY; BINDING SITE; CELL DAMAGE; CELL DIVISION; COMPUTER PROGRAM; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG DESIGN PROGRAM; DRUG STRUCTURE; FRANCISELLA TULARENSIS; GENETIC ALGORITHM; HIGH THROUGHPUT SCREENING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STRUCTURE BASED DRUG PROGRAM; ANIMAL; BACTERIAL INFECTIONS; BACTERIUM; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; HUMAN; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS);

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; DRUG DESIGN; DRUG DISCOVERY; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84905921172     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2014.05.008     Document Type: Article

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