-
1
-
-
39449103059
-
The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America
-
Spellberg, B.; Guidos, R.; Gilbert, D.; Bradley, J.; Boucher, H. W.; Scheld, W. M.; Bartlett, J. G.; Edwards, J., Jr. The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America Clin. Infect. Dis. 2008, 46, 155-164
-
(2008)
Clin. Infect. Dis.
, vol.46
, pp. 155-164
-
-
Spellberg, B.1
Guidos, R.2
Gilbert, D.3
Bradley, J.4
Boucher, H.W.5
Scheld, W.M.6
Bartlett, J.G.7
Edwards Jr., J.8
-
3
-
-
77149165713
-
Updated functional classification of β-lactamases
-
Bush, K.; Jacoby, G. A. Updated functional classification of β-lactamases Antimicrob. Agents Chemother. 2010) 54, 969-976
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 969-976
-
-
Bush, K.1
Jacoby, G.A.2
-
4
-
-
1242352586
-
Augmentin (amoxicillin/clavulanate) in the treatment of community-acquired respiratory tract infection: A review of the continuing development of an innovative antimicrobial agent
-
White, A. R.; Kaye, C.; Poupard, J.; Pypstra, R.; Woodnutt, G.; Wynne, B. J. Augmentin (amoxicillin/clavulanate) in the treatment of community-acquired respiratory tract infection: A review of the continuing development of an innovative antimicrobial agent Antimicrob. Chemother. 2004, 53 (Suppl. S1) i3-i20
-
(2004)
Antimicrob. Chemother.
, vol.53
, Issue.SUPPL. S1
-
-
White, A.R.1
Kaye, C.2
Poupard, J.3
Pypstra, R.4
Woodnutt, G.5
Wynne, B.J.6
-
5
-
-
74249108028
-
Three decades of β-lactamase inhibitors
-
Drawz, S. M.; Bonomo, R. A. Three decades of β-lactamase inhibitors Clin. Microbiol. Rev. 2010, 23, 160-201
-
(2010)
Clin. Microbiol. Rev.
, vol.23
, pp. 160-201
-
-
Drawz, S.M.1
Bonomo, R.A.2
-
6
-
-
77951097617
-
Evolving carbapenemases: Can medicinal chemists advance one step ahead of the coming storm?
-
Oelschlaeger, P.; Ai, N.; DuPrez, K. T.; Welsh, W. J.; Toney, J. H. Evolving carbapenemases: Can medicinal chemists advance one step ahead of the coming storm? J. Med. Chem. 2010, 53, 3013-3027
-
(2010)
J. Med. Chem.
, vol.53
, pp. 3013-3027
-
-
Oelschlaeger, P.1
Ai, N.2
Duprez, K.T.3
Welsh, W.J.4
Toney, J.H.5
-
7
-
-
80054693925
-
Carbapenems: Past, present, and future
-
Papp-Wallace, K. M.; Endimiani, A.; Taracila, M. A.; Bonomo, R. A Carbapenems: Past, present, and future Antimicrob. Agents Chemother. 2011, 5, 4943-4960
-
(2011)
Antimicrob. Agents Chemother.
, vol.5
, pp. 4943-4960
-
-
Papp-Wallace, K.M.1
Endimiani, A.2
Taracila, M.A.3
Bonomo, R.A.4
-
8
-
-
84863905057
-
Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor
-
Ehmann, D. E.; Jahić, H.; Ross, P. L.; Gu, R.-F.; Hu, J.; Kern, G.; Walkup, G. K.; Fisher, S. L. Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 11663-11668
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 11663-11668
-
-
Ehmann, D.E.1
Jahić, H.2
Ross, P.L.3
Gu, R.-F.4
Hu, J.5
Kern, G.6
Walkup, G.K.7
Fisher, S.L.8
-
9
-
-
0013983654
-
Fine structure of sporulation in Bacillus cereus grown in a chemically defined medium
-
Ellar, D. J.; Lundgren, D. G. Fine structure of sporulation in Bacillus cereus grown in a chemically defined medium J. Bacteriol. 1966, 92, 1748-1764
-
(1966)
J. Bacteriol.
, vol.92
, pp. 1748-1764
-
-
Ellar, D.J.1
Lundgren, D.G.2
-
10
-
-
78649697323
-
Emerging carbapenemases: A global perspective
-
Walsh, T. R. Emerging carbapenemases: A global perspective Int. J. Antimicrob. Agents 2010, 36 (Suppl. 3) S8-S14
-
(2010)
Int. J. Antimicrob. Agents
, vol.36
, Issue.SUPPL. 3
-
-
Walsh, T.R.1
-
11
-
-
79955453026
-
Metallo-β-lactamases: A last frontier for β-lactams?
-
Cornaglia, G.; Giamarellou, H.; Maria Rossolini, G. Metallo-β- lactamases: A last frontier for β-lactams? Lancet Infect. Dis. 2011, 11, 381-393
-
(2011)
Lancet Infect. Dis.
, vol.11
, pp. 381-393
-
-
Cornaglia, G.1
Giamarellou, H.2
Maria Rossolini, G.3
-
12
-
-
84866426322
-
2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases
-
Chen, P.; Horton, L. B.; Mikulski, R. L.; Deng, L.; Sundriyal, S.; Palzkill, T.; Song, Y. 2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases Bioorg. Med. Chem. Lett. 2012, 22, 6229-6232
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 6229-6232
-
-
Chen, P.1
Horton, L.B.2
Mikulski, R.L.3
Deng, L.4
Sundriyal, S.5
Palzkill, T.6
Song, Y.7
-
13
-
-
0035943678
-
Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-β-lactamase
-
Toney, J. H.; Hammond, G. G.; Fitzgerald, P. M. D.; Sharma, N.; Balkovec, J. M.; Rouen, G. P.; Olson, S. H.; Hammond, M. L.; Greenlee, M. L.; Gao, Y. D. Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-β- lactamase J. Biol. Chem. 2001, 276, 31913-31918
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31913-31918
-
-
Toney, J.H.1
Hammond, G.G.2
Fitzgerald, P.M.D.3
Sharma, N.4
Balkovec, J.M.5
Rouen, G.P.6
Olson, S.H.7
Hammond, M.L.8
Greenlee, M.L.9
Gao, Y.D.10
-
14
-
-
13144295022
-
Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-β-lactamase
-
Toney, J. H.; Fitzgerald, P. M.; Grover-Sharma, N.; Olson, S. H.; May, W. J.; Sundelof, J. G.; Vanderwall, D. E.; Cleary, K. A.; Grant, S. K.; Wu, J. K.; Kozarich, J. W.; Pompliano, D. L.; Hammond, G. G. Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-β-lactamase Chem. Biol. 1998, 5, 185-196
-
(1998)
Chem. Biol.
, vol.5
, pp. 185-196
-
-
Toney, J.H.1
Fitzgerald, P.M.2
Grover-Sharma, N.3
Olson, S.H.4
May, W.J.5
Sundelof, J.G.6
Vanderwall, D.E.7
Cleary, K.A.8
Grant, S.K.9
Wu, J.K.10
Kozarich, J.W.11
Pompliano, D.L.12
Hammond, G.G.13
-
15
-
-
77955915532
-
NH-1,2,3-Triazole-based inhibitors of the VIM-2 metallo-β-lactamase: Synthesis and structure-activity studies
-
Weide, T.; Saldanha, S. A.; Minond, D.; Spicer, T. P.; Fotsing, J. R.; Spaargaren, M.; Frère, J.-M.; Bebrone, C.; Sharpless, K. B.; Hodder, P. S.; Fokin, V. V. NH-1,2,3-Triazole-based inhibitors of the VIM-2 metallo-β-lactamase: Synthesis and structure-activity studies ACS Med. Chem. Lett. 2010, 1, 150-154
-
(2010)
ACS Med. Chem. Lett.
, vol.1
, pp. 150-154
-
-
Weide, T.1
Saldanha, S.A.2
Minond, D.3
Spicer, T.P.4
Fotsing, J.R.5
Spaargaren, M.6
Frère, J.-M.7
Bebrone, C.8
Sharpless, K.B.9
Hodder, P.S.10
Fokin, V.V.11
-
16
-
-
45449088355
-
Structural basis for the broad-spectrum inhibition of metallo-β-lactamases by thiols
-
Liénard, B. M. R.; Garau, G.; Horsfall, L.; Karsisiotis, A. I.; Damblon, C.; Lassaux, P.; Papamicael, C.; Roberts, G. C. K.; Galleni, M.; Dideberg, O.; Frère, J.-M.; Schofield, C. J. Structural basis for the broad-spectrum inhibition of metallo-β-lactamases by thiols Org. Biomol. Chem. 2008, 6, 2282-2294
-
(2008)
Org. Biomol. Chem.
, vol.6
, pp. 2282-2294
-
-
Liénard, B.M.R.1
Garau, G.2
Horsfall, L.3
Karsisiotis, A.I.4
Damblon, C.5
Lassaux, P.6
Papamicael, C.7
Roberts, G.C.K.8
Galleni, M.9
Dideberg, O.10
Frère, J.-M.11
Schofield, C.J.12
-
17
-
-
39149098822
-
Dynamic combinatorial mass spectrometry leads to metallo-β-lactamase inhibitors
-
Liénard, B. M., R.; Hüting, R.; Lassaux, P.; Galleni, M.; Frère, J.-M.; Schofield, C. J. Dynamic combinatorial mass spectrometry leads to metallo-β-lactamase inhibitors J. Med. Chem. 2008, 51, 684-688
-
(2008)
J. Med. Chem.
, vol.51
, pp. 684-688
-
-
Liénard, B.M..R.1
Hüting, R.2
Lassaux, P.3
Galleni, M.4
Frère, J.-M.5
Schofield, C.J.6
-
18
-
-
0030598201
-
Trifluoromethyl alcohol and ketone inhibitors of metallo-β- lactamases
-
Walter, M. W.; Felici, A.; Galleni, M.; Paul Soto, R.; Adlington, R. M.; Baldwin, J. E.; Frère, J.-M.; Gololobov, M.; Schofield, C. J. Trifluoromethyl alcohol and ketone inhibitors of metallo-β-lactamases Bioorg. Med. Chem. Lett. 1996, 6, 2455-2458
-
(1996)
Bioorg. Med. Chem. Lett.
, vol.6
, pp. 2455-2458
-
-
Walter, M.W.1
Felici, A.2
Galleni, M.3
Paul Soto, R.4
Adlington, R.M.5
Baldwin, J.E.6
Frère, J.-M.7
Gololobov, M.8
Schofield, C.J.9
-
19
-
-
84879067434
-
Metallo-β-lactamase: Inhibitors and reporter substrates
-
Fast, W.; Sutton, L. D. Metallo-β-lactamase: Inhibitors and reporter substrates Biochim. Biophys. Acta, Proteins Proteomics 2013, 1834, 1648-1659
-
(2013)
Biochim. Biophys. Acta, Proteins Proteomics
, vol.1834
, pp. 1648-1659
-
-
Fast, W.1
Sutton, L.D.2
-
20
-
-
16644379888
-
Metallo-β-lactamase inhibitors: Promise for the future?
-
Toney, J. H.; Moloughney, J. G. Metallo-β-lactamase inhibitors: Promise for the future? Curr. Opin. Invest. Drugs 2004, 5, 823-826
-
(2004)
Curr. Opin. Invest. Drugs
, vol.5
, pp. 823-826
-
-
Toney, J.H.1
Moloughney, J.G.2
-
21
-
-
33746312394
-
Approach to the inhibition of metallo-β-lactamases
-
Spencer, J.; Walsh, T. R.; New, A. Approach to the inhibition of metallo-β-lactamases Angew. Chem., Int. Ed. 2006, 45, 1022-1026
-
(2006)
Angew. Chem., Int. Ed.
, vol.45
, pp. 1022-1026
-
-
Spencer, J.1
Walsh, T.R.2
New, A.3
-
22
-
-
0037399075
-
Analysis of the importance of the metallo-β-lactamase active site loop in substrate binding and catalysis
-
Moali, C.; Anne, C.; Lamotte-Brasseur, J.; Groslambert, S.; Devreese, B.; Van Beeumen, J.; Galleni, M.; Frère, J.-M. Analysis of the importance of the metallo-β-lactamase active site loop in substrate binding and catalysis Chem. Biol. 2003, 10, 319-329
-
(2003)
Chem. Biol.
, vol.10
, pp. 319-329
-
-
Moali, C.1
Anne, C.2
Lamotte-Brasseur, J.3
Groslambert, S.4
Devreese, B.5
Van Beeumen, J.6
Galleni, M.7
Frère, J.-M.8
-
23
-
-
84872853235
-
Crystal structures of Pseudomonas aeruginosa GIM-1: Active-site plasticity in metallo-β-lactamases
-
Saradhi Borra, P.; Samuelsen, Ø.; Spencer, J.; Walsh, T. R.; Sjo Lorentzen, M.; Leirose, H.-K. S. Crystal structures of Pseudomonas aeruginosa GIM-1: Active-site plasticity in metallo-β-lactamases Antimicrob. Agents Chemother. 2013, 57, 848-854
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, pp. 848-854
-
-
Saradhi Borra, P.1
Samuelsen Ø2
Spencer, J.3
Walsh, T.R.4
Sjo Lorentzen, M.5
Leirose, H.-K.S.6
-
24
-
-
44049099383
-
Assays for β-lactamase activity and inhibition
-
Viswanatha, T.; Marrone, L.; Goodfellow, V.; Dmitrienko, G. I. Assays for β-lactamase activity and inhibition Methods Mol. Med. 2008, 142, 239-260
-
(2008)
Methods Mol. Med.
, vol.142
, pp. 239-260
-
-
Viswanatha, T.1
Marrone, L.2
Goodfellow, V.3
Dmitrienko, G.I.4
-
25
-
-
84867811998
-
Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division
-
Kocaoglu, O.; Calvo, R. A.; Sham, L.-T.; Cozy, L. M.; Lanning, B. R.; Francis, S.; Winkler, M. E.; Kearns, D. B.; Carlson, E. E. Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division ACS Chem. Biol. 2012, 7, 1746-1753
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 1746-1753
-
-
Kocaoglu, O.1
Calvo, R.A.2
Sham, L.-T.3
Cozy, L.M.4
Lanning, B.R.5
Francis, S.6
Winkler, M.E.7
Kearns, D.B.8
Carlson, E.E.9
-
26
-
-
61949407969
-
Exploiting a bacterial drug-resistance mechanism: A light-activated construct for the destruction of MRSA
-
Zheng, X.; Sallium, U. W.; Verma, S.; Athar, H.; Evans, C. L.; Hasan, T. Exploiting a bacterial drug-resistance mechanism: A light-activated construct for the destruction of MRSA Angew. Chem., Int. Ed. 2009, 48, 2148-2151
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, pp. 2148-2151
-
-
Zheng, X.1
Sallium, U.W.2
Verma, S.3
Athar, H.4
Evans, C.L.5
Hasan, T.6
-
27
-
-
0020026390
-
In vitro evaluation of CENTA, a new β-lactamase-susceptible chromogenic cephalosporin reagent
-
Jones, R. N.; Wilson, H. W.; Novick, W. J., Jr.; Barry, A. L.; Thornberry, C. In vitro evaluation of CENTA, a new β-lactamase-susceptible chromogenic cephalosporin reagent J. Clin. Microbiol. 1982, 15, 954-958
-
(1982)
J. Clin. Microbiol.
, vol.15
, pp. 954-958
-
-
Jones, R.N.1
Wilson, H.W.2
Novick Jr., W.J.3
Barry, A.L.4
Thornberry, C.5
-
28
-
-
0020083977
-
In vitro evaluation of pyridine-2-azo- p -dimethylaniline cephalosporin, a new diagnostic chromogenic reagent, and comparison with nitrocefin, cephacetrile, and other β-lactam compounds
-
Jones, R. N.; Wilson, H. W.; Novick, J.R. In vitro evaluation of pyridine-2-azo- p -dimethylaniline cephalosporin, a new diagnostic chromogenic reagent, and comparison with nitrocefin, cephacetrile, and other β-lactam compounds J. Clin. Microbiol. 1982, 15, 677-683
-
(1982)
J. Clin. Microbiol.
, vol.15
, pp. 677-683
-
-
Jones, R.N.1
Wilson, H.W.2
Novick, J.R.3
-
29
-
-
0019192547
-
β-Lactamase detection by three simple methods: Intralactam, nitrocefin and acidimetric
-
Shannon, K.; Phillips, I. β-Lactamase detection by three simple methods: Intralactam, nitrocefin and acidimetric J. Antimicrob. Chemother. 1980, 6, 617-621
-
(1980)
J. Antimicrob. Chemother.
, vol.6
, pp. 617-621
-
-
Shannon, K.1
Phillips, I.2
-
30
-
-
0043195272
-
Novel fluorogenic substrates for imaging β-lactamase gene expression
-
Gao, W.; Xing, B.; Tsien, R. Y.; Rao, J. Novel fluorogenic substrates for imaging β-lactamase gene expression J. Am. Chem. Soc. 2003, 125, 11146-11147
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 11146-11147
-
-
Gao, W.1
Xing, B.2
Tsien, R.Y.3
Rao, J.4
-
31
-
-
80054987081
-
Fluorogenic cephalosporin substrates for β-lactamase TEM-1
-
Rukavishnikov, A.; Gee, K. R.; Johnson, I.; Corry, S. Fluorogenic cephalosporin substrates for β-lactamase TEM-1 Anal. Biochem. 2011, 419, 9-16
-
(2011)
Anal. Biochem.
, vol.419
, pp. 9-16
-
-
Rukavishnikov, A.1
Gee, K.R.2
Johnson, I.3
Corry, S.4
-
32
-
-
84874646865
-
A novel fluorogenic substrate for dinuclear Zn(II)-containing metallo-β-lactamases
-
Zhang, Y.-L.; Xiao, J.-M.; Feng, J.-L.; Yang, K.-W.; Feng, L.; Zhou, L.-S.; Crowder, M. W. A novel fluorogenic substrate for dinuclear Zn(II)-containing metallo-β-lactamases Bioorg. Med. Chem. Lett. 2013, 23, 1676-1679
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 1676-1679
-
-
Zhang, Y.-L.1
Xiao, J.-M.2
Feng, J.-L.3
Yang, K.-W.4
Feng, L.5
Zhou, L.-S.6
Crowder, M.W.7
-
33
-
-
34848887128
-
Substrate for in vivo imaging of β-lactamase activity
-
Yao, H.; So, M.-K.; Rao, J.; Bioluminogenic, A. Substrate for in vivo imaging of β-lactamase activity Angew. Chem., Int. Ed. 2007, 46, 7031-7034
-
(2007)
Angew. Chem., Int. Ed.
, vol.46
, pp. 7031-7034
-
-
Yao, H.1
So, M.-K.2
Rao, J.3
Bioluminogenic, A.4
-
34
-
-
78650350119
-
Multicolor protein labeling in living cells using mutant β-lactamase-tag technology
-
Watanabe, S.; Mizukami, S.; Hori, Y.; Kikuchi, K. Multicolor protein labeling in living cells using mutant β-lactamase-tag technology Bioconjugate Chem. 2010, 21, 2320-2326
-
(2010)
Bioconjugate Chem.
, vol.21
, pp. 2320-2326
-
-
Watanabe, S.1
Mizukami, S.2
Hori, Y.3
Kikuchi, K.4
-
35
-
-
84856252572
-
No-wash protein labeling with designed fluorogenic probes and application to real-time pulse-chase analysis
-
Mizukami, S.; Watanabe, S.; Akimoto, Y.; Kikuchi, K. No-wash protein labeling with designed fluorogenic probes and application to real-time pulse-chase analysis J. Am. Chem. Soc. 2012, 134, 1623-1629
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 1623-1629
-
-
Mizukami, S.1
Watanabe, S.2
Akimoto, Y.3
Kikuchi, K.4
-
36
-
-
84855829722
-
Enzyme responsive luminescent ruthenium(II) cephalosporin probe for intracellular imaging and photoinactivation of antibiotics resistant bacteria
-
Shao, Q.; Xing, B. Enzyme responsive luminescent ruthenium(II) cephalosporin probe for intracellular imaging and photoinactivation of antibiotics resistant bacteria Chem. Commun. 2012, 48, 1739-1741
-
(2012)
Chem. Commun.
, vol.48
, pp. 1739-1741
-
-
Shao, Q.1
Xing, B.2
-
37
-
-
80054999128
-
Structural and kinetic studies on metallo-β-lactamase IMP-1
-
IMP-1
-
Griffin, D. H.; Richmond, T. K.; Sanchez, C.; Jon Moller, A.; Breece, R. M.; Tierney, D. L.; Bennett, B.; Crowder, M. W. Structural and kinetic studies on metallo-β-lactamase IMP-1 Biochemistry 2011, 50, 9125-9134 (IMP-1)
-
(2011)
Biochemistry
, vol.50
, pp. 9125-9134
-
-
Griffin, D.H.1
Richmond, T.K.2
Sanchez, C.3
Jon Moller, A.4
Breece, R.M.5
Tierney, D.L.6
Bennett, B.7
Crowder, M.W.8
-
38
-
-
0036566439
-
Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-β-lactamase
-
Bc II
-
de Seny, D.; Prosperi-Meys, C.; Bebrone, C.; Maria Rossolini, G.; Page, M. I.; Noel, P.; Frère, J.-M.; Galleni, M. Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-β-lactamase Biochem. J. 2002, 363, 687-696 (Bc II)
-
(2002)
Biochem. J.
, vol.363
, pp. 687-696
-
-
De Seny, D.1
Prosperi-Meys, C.2
Bebrone, C.3
Maria Rossolini, G.4
Page, M.I.5
Noel, P.6
Frère, J.-M.7
Galleni, M.8
-
39
-
-
80955155502
-
Structure of New Delhi metallo-β-lactamase 1 (NDM-1)
-
NDM-1
-
Green, V. L.; Verma, A.; Owens, R. J.; Phillipsa, S. E. V.; Carr, S. B. Structure of New Delhi metallo-β-lactamase 1 (NDM-1) Acta Crystallogr. 2011, F67, 1160-1164 (NDM-1)
-
(2011)
Acta Crystallogr.
, vol.67
, pp. 1160-1164
-
-
Green, V.L.1
Verma, A.2
Owens, R.J.3
Phillipsa, S.E.V.4
Carr, S.B.5
-
40
-
-
34247846396
-
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications
-
Berrow, N. S.; Alderton, D.; Sainsbury, S.; Nettleship, J.; Assenberg, R.; Rahman, N.; Stuart, D. I.; Owens, R. J. A versatile ligation-independent cloning method suitable for high-throughput expression screening applications Nucleic Acids Res. 2007, 35, e45
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 45
-
-
Berrow, N.S.1
Alderton, D.2
Sainsbury, S.3
Nettleship, J.4
Assenberg, R.5
Rahman, N.6
Stuart, D.I.7
Owens, R.J.8
-
41
-
-
0035018312
-
CENTA as a chromogenic substrate for studying β-lactamases
-
Bebrone, C.; Moali, C.; Mahy, F.; Rival, S.; Docquier, J.-D.; Maria Rossolini, G.; Fastrez, J.; Pratt, R. F.; Frère, J.-M.; Galleni, M. CENTA as a chromogenic substrate for studying β-lactamases Antimicrob. Agents Chemother. 2001, 45, 1868-1871
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1868-1871
-
-
Bebrone, C.1
Moali, C.2
Mahy, F.3
Rival, S.4
Docquier, J.-D.5
Maria Rossolini, G.6
Fastrez, J.7
Pratt, R.F.8
Frère, J.-M.9
Galleni, M.10
-
42
-
-
0014821771
-
3- cephem by oxidation-reduction at sulfur
-
3-cephem by oxidation-reduction at sulfur J. Org. Chem. 1970, 35, 2430-2433
-
(1970)
J. Org. Chem.
, vol.35
, pp. 2430-2433
-
-
Kaiser, G.V.1
Cooper, R..D.G.2
Koehler, R.E.3
Murphy, C.F.4
Webber, J.A.5
Wright, I.G.6
Van Heyningen, E.M.7
-
44
-
-
84866921607
-
Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe
-
Xie, H.; Mire, J.; Kong, Y.; Chang, M.; Hassounah, H. A.; Thornton, C. N.; Sacchettini, J. C.; Cirillo, J. D.; Rao, J. Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe Nat. Chem. 2012, 4, 802-809
-
(2012)
Nat. Chem.
, vol.4
, pp. 802-809
-
-
Xie, H.1
Mire, J.2
Kong, Y.3
Chang, M.4
Hassounah, H.A.5
Thornton, C.N.6
Sacchettini, J.C.7
Cirillo, J.D.8
Rao, J.9
-
45
-
-
80052552771
-
Structure of apo- and monometalated forms of NDM-1 - A highly potent carbapenem-hydrolyzing metallo-β-lactamase
-
Kim, Y.; Tesar, C.; Mire, J.; Jedrzejczak, R.; Binkowski, A.; Babnigg, G.; Sacchettini, J.; Joachimiak, A. Structure of apo- and monometalated forms of NDM-1-A highly potent carbapenem-hydrolyzing metallo-β-lactamase PLoS One 2011, 6, e24621
-
(2011)
PLoS One
, vol.6
, pp. 24621
-
-
Kim, Y.1
Tesar, C.2
Mire, J.3
Jedrzejczak, R.4
Binkowski, A.5
Babnigg, G.6
Sacchettini, J.7
Joachimiak, A.8
-
46
-
-
0037329156
-
On functional and structural heterogeneity of VIM-type metallo-β-lactamases
-
Docquier, J.-D.; Lamotte-Brasseur, J.; Galleni, M.; Amicosante, G.; Frère, J.-M.; Maria Rossolini, G. On functional and structural heterogeneity of VIM-type metallo-β-lactamases J. Antimicrob. Chemother. 2003, 51, 257-266
-
(2003)
J. Antimicrob. Chemother.
, vol.51
, pp. 257-266
-
-
Docquier, J.-D.1
Lamotte-Brasseur, J.2
Galleni, M.3
Amicosante, G.4
Frère, J.-M.5
Maria Rossolini, G.6
-
47
-
-
0032925064
-
Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-β-lactamase IMP-1 produced by Escherichia coli
-
Laraki, N.; Franceschini, N.; Rossolini, G. M.; Santucci, P.; Meunier, C.; de Pauw, E.; Amicosante, G.; Frère, J.-M.; Galleni, M. Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-β-lactamase IMP-1 produced by Escherichia coli Antimicrob. Agents Chemother. 1999, 43, 902-906
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 902-906
-
-
Laraki, N.1
Franceschini, N.2
Rossolini, G.M.3
Santucci, P.4
Meunier, C.5
De Pauw, E.6
Amicosante, G.7
Frère, J.-M.8
Galleni, M.9
-
48
-
-
0037310952
-
Biochemical characterization of the acquired metallo-β-lactamase SPM-1 from Pseudomonas aeruginosa
-
Murphy, T. A.; Simm, A. M.; Toleman, M. A.; Jones, R. N.; Walsh, T. R. Biochemical characterization of the acquired metallo-β-lactamase SPM-1 from Pseudomonas aeruginosa Antimicrob. Agents Chemother. 2003, 47, 582-587
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 582-587
-
-
Murphy, T.A.1
Simm, A.M.2
Toleman, M.A.3
Jones, R.N.4
Walsh, T.R.5
-
49
-
-
0032582569
-
Mono- and binuclear Zn-β-lactamase from Bacteroides fragilis: Catalytic and structural roles of the zinc ions
-
Paul-Soto, R.; Hernadez-Valladares, M.; Fonzé, E.; Goussard, S.; Courvalin, P.; Frère, J.-M. Mono- and binuclear Zn-β-lactamase from Bacteroides fragilis: Catalytic and structural roles of the zinc ions FEBS Lett. 1998, 438, 137-140
-
(1998)
FEBS Lett.
, vol.438
, pp. 137-140
-
-
Paul-Soto, R.1
Hernadez-Valladares, M.2
Fonzé, E.3
Goussard, S.4
Courvalin, P.5
Frère, J.-M.6
-
50
-
-
0028837277
-
Kinetic Analysis of extension of substrate specificity with Xanthomonas maltophilia, Aeromonas hydrophila, and Bacillus cereus metallo-β-lactamases
-
Felici, A.; Amicosante, G. Kinetic Analysis of extension of substrate specificity with Xanthomonas maltophilia, Aeromonas hydrophila, and Bacillus cereus metallo-β-lactamases Antimicrob. Agents Chemother. 1995, 39, 192-199
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 192-199
-
-
Felici, A.1
Amicosante, G.2
-
51
-
-
71249134038
-
NDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India
-
NDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India Antimicrob. Agents Chemother. 2009, 53, 5046-5054
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 5046-5054
-
-
Young, D.1
Toleman, M.A.2
Giske, G.C.3
Cho, C.H.4
Sundman, K.5
Lee, K.6
Walsh, T.R.7
-
52
-
-
20544440614
-
Inhibitors of metallo-β-lactamase generated from β-lactam antibiotics
-
Badarau, A.; Llinás, A.; Laws, A. P.; Damblon, C.; Page, M. I. Inhibitors of metallo-β-lactamase generated from β-lactam antibiotics Biochemistry 2005, 44, 8578-8589
-
(2005)
Biochemistry
, vol.44
, pp. 8578-8589
-
-
Badarau, A.1
Llinás, A.2
Laws, A.P.3
Damblon, C.4
Page, M.I.5
-
53
-
-
0034819514
-
Inactivation of Aeromonas hydrophila metallo-β-lactamase by cephamycins and moxalactam
-
Astrid Zervosen, A.; Hernandez Valladares, M.; Devreese, B.; Prosperi-Meys, C.; Adolph, H.-W.; Sandra Mercuri, P.; Vanhove, M.; Amicosante, G.; van Beeumen, J.; Frère, J.-M.; Galleni, M. Inactivation of Aeromonas hydrophila metallo-β-lactamase by cephamycins and moxalactam Eur. J. Biochem. 2001, 268, 3840-3850
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 3840-3850
-
-
Astrid Zervosen, A.1
Hernandez Valladares, M.2
Devreese, B.3
Prosperi-Meys, C.4
Adolph, H.-W.5
Sandra Mercuri, P.6
Vanhove, M.7
Amicosante, G.8
Van Beeumen, J.9
Frère, J.-M.10
Galleni, M.11
-
54
-
-
80054691298
-
Biochemical characterization of Sfh-I, a subclass B2 metallo-β- lactamase from Serratia fonticola UTAD54
-
Fonseca, F.; Arthur, C. J.; Bromley, E. H. C.; Samyn, B.; Moerman, P.; Saavedra, M. J.; Correia, A.; Spencer, J. Biochemical characterization of Sfh-I, a subclass B2 metallo-β-lactamase from Serratia fonticola UTAD54 Antimicrob. Agents Chemother. 2011, 55, 5392-5395
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 5392-5395
-
-
Fonseca, F.1
Arthur, C.J.2
Bromley, E.H.C.3
Samyn, B.4
Moerman, P.5
Saavedra, M.J.6
Correia, A.7
Spencer, J.8
-
55
-
-
12244297122
-
Thiols as classical and slow-binding inhibitors of IMP-1 and other binuclear metallo-β-lactamases
-
Siemann, S.; Clarke, A. J.; Viswanatha, T.; Dmitrienko, G. I. Thiols as classical and slow-binding inhibitors of IMP-1 and other binuclear metallo-β-lactamases Biochemistry 2003, 42, 1673-1683
-
(2003)
Biochemistry
, vol.42
, pp. 1673-1683
-
-
Siemann, S.1
Clarke, A.J.2
Viswanatha, T.3
Dmitrienko, G.I.4
-
56
-
-
20544440614
-
Inhibitors of metallo-β-lactamase generated from β-lactam antibiotics
-
Badarau, A.; Llinas, A.; Laws, A. P.; Damblon, C.; Page, M. I. Inhibitors of metallo-β-lactamase generated from β-lactam antibiotics Biochemistry 2005, 44, 8578-8589
-
(2005)
Biochemistry
, vol.44
, pp. 8578-8589
-
-
Badarau, A.1
Llinas, A.2
Laws, A.P.3
Damblon, C.4
Page, M.I.5
-
57
-
-
33644948482
-
Crystal structure of Pseudomonas aeruginosa SPM-1 provides insights into variable zinc affinity of metallo-β-lactamases
-
Murphy, T. A; Catto, L. E.; Halford, S. E.; Hadfield, A. T.; Minor, W.; Walsh, T. R.; Spencer, J. Crystal structure of Pseudomonas aeruginosa SPM-1 provides insights into variable zinc affinity of metallo-β-lactamases J. Mol. Biol. 2006, 357, 890-903
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 890-903
-
-
Murphy, T.A.1
Catto, L.E.2
Halford, S.E.3
Hadfield, A.T.4
Minor, W.5
Walsh, T.R.6
Spencer, J.7
-
58
-
-
79957618735
-
Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism
-
Zhang, H.; Hao, Q. Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism FASEB J. 2011, 25, 2574-2582
-
(2011)
FASEB J.
, vol.25
, pp. 2574-2582
-
-
Zhang, H.1
Hao, Q.2
-
59
-
-
37349007671
-
The three-dimensional structure of VIM-2, a Zn-β-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form
-
Garcia-Saez, I.; Docquier, J. D.; Rossolini, G. M.; Dideberg, O. The three-dimensional structure of VIM-2, a Zn-β-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form J. Mol. Biol. 2008, 375, 604-611
-
(2008)
J. Mol. Biol.
, vol.375
, pp. 604-611
-
-
Garcia-Saez, I.1
Docquier, J.D.2
Rossolini, G.M.3
Dideberg, O.4
-
60
-
-
0029705324
-
Automated docking of flexible ligands: Applications of AutoDock
-
Goodsell, D. S.; Morris, G. M.; Olson, A. J. Automated docking of flexible ligands: Applications of AutoDock J. Mol. Recognit. 1996, 9, 1-5
-
(1996)
J. Mol. Recognit.
, vol.9
, pp. 1-5
-
-
Goodsell, D.S.1
Morris, G.M.2
Olson, A.J.3
-
61
-
-
70349932423
-
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
-
Morris, G. M.; Huey, R.; Lindstrom, W.; Sanner, M. F.; Belew, R. K.; Goodsell, D. S.; Olson, A. J. AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility J. Comput. Chem. 2009, 30, 2785-2791
-
(2009)
J. Comput. Chem.
, vol.30
, pp. 2785-2791
-
-
Morris, G.M.1
Huey, R.2
Lindstrom, W.3
Sanner, M.F.4
Belew, R.K.5
Goodsell, D.S.6
Olson, A.J.7
-
62
-
-
0027586682
-
SPROUT: A program for structure generation
-
Gillet, V.; Johnson, A. P.; Mata, P.; Sike, S.; Williams, P. SPROUT: A program for structure generation J. Comput.-Aided Mol. Des. 1993, 7, 127-153
-
(1993)
J. Comput.-Aided Mol. Des.
, vol.7
, pp. 127-153
-
-
Gillet, V.1
Johnson, A.P.2
Mata, P.3
Sike, S.4
Williams, P.5
-
63
-
-
0028167547
-
SPROUT: Recent developments in the de novo design of molecules
-
Gillet, V. J.; Newell, W.; Mata, P.; Myatt, G.; Sike, S.; Zsoldos, Z.; Johnson, A. P. SPROUT: Recent developments in the de novo design of molecules J. Chem. Inf. Comput. Sci. 1994, 34, 207-217
-
(1994)
J. Chem. Inf. Comput. Sci.
, vol.34
, pp. 207-217
-
-
Gillet, V.J.1
Newell, W.2
Mata, P.3
Myatt, G.4
Sike, S.5
Zsoldos, Z.6
Johnson, A.P.7
-
64
-
-
84857023787
-
Computational analysis of pathogen-borne metallo β-lactamases reveals discriminating structural features between B1 types
-
Cadag, E.; Vitalis, E.; Lennox, K. P.; Zhou, C. L. E.; Zemla, A. T. Computational analysis of pathogen-borne metallo β-lactamases reveals discriminating structural features between B1 types BMC Res. Notes 2012, 5, 96
-
(2012)
BMC Res. Notes
, vol.5
, pp. 96
-
-
Cadag, E.1
Vitalis, E.2
Lennox, K.P.3
Zhou, C.L.E.4
Zemla, A.T.5
-
65
-
-
65649135802
-
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure
-
Stubbs, C. J.; Loenarz, C.; Mecinović, J.; Kheng Yeoh, K.; Hindley, N.; Liénard, B. M.; Sobott, F.; Schofield, C. J.; Flashman, E. Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure J. Med. Chem. 2009, 52, 2799-2805
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2799-2805
-
-
Stubbs, C.J.1
Loenarz, C.2
Mecinović, J.3
Kheng Yeoh, K.4
Hindley, N.5
Liénard, B.M.6
Sobott, F.7
Schofield, C.J.8
Flashman, E.9
-
66
-
-
79953891392
-
Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors
-
Tian, Y.-M.; Yeoh, K. K.; Lee, M. K.; Eriksson, T.; Kessler, B. M.; Kramer, H. B.; Edelmann, M. J.; Willam, C.; Pugh, C. W.; Schofield, C. J.; Ratcliffe, P. J. Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors J. Biol. Chem. 2011, 286, 13041-13051
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13041-13051
-
-
Tian, Y.-M.1
Yeoh, K.K.2
Lee, M.K.3
Eriksson, T.4
Kessler, B.M.5
Kramer, H.B.6
Edelmann, M.J.7
Willam, C.8
Pugh, C.W.9
Schofield, C.J.10
Ratcliffe, P.J.11
-
67
-
-
0038419647
-
Coordination geometries of metal ions in D- or L-captopril-inhibited metallo-β-lactamases
-
Heinz, U.; Bauer, R.; Wommer, S.; Meyer-Klaucke, W.; Papamichaels, C.; Bateson, J.; Adolph, H.-W. Coordination geometries of metal ions in D- or L-captopril-inhibited metallo-β-lactamases J. Biol. Chem. 2003, 278, 20659-20666
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20659-20666
-
-
Heinz, U.1
Bauer, R.2
Wommer, S.3
Meyer-Klaucke, W.4
Papamichaels, C.5
Bateson, J.6
Adolph, H.-W.7
-
68
-
-
84863976350
-
New Delhi metallo-β-lactamase: Structural insights into β-lactam recognition and inhibition
-
King, D. T.; Worrall, L. J.; Gruninger, R.; Strynadka, N. C. New Delhi metallo-β-lactamase: Structural insights into β-lactam recognition and inhibition J. Am. Chem. Soc. 2012, 134, 11362-11365
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 11362-11365
-
-
King, D.T.1
Worrall, L.J.2
Gruninger, R.3
Strynadka, N.C.4
-
70
-
-
80051979418
-
A structural view of the antibiotic degradation enzyme NDM-1 from a superbug
-
Guo, Y.; Wang, J.; Niu, G.; Shui, W.; Sun, Y.; Zhou, H.; Zhang, Y.; Yang, C.; Lou, Z.; Rao, Z. A structural view of the antibiotic degradation enzyme NDM-1 from a superbug Protein Cell 2011, 2, 384-394
-
(2011)
Protein Cell
, vol.2
, pp. 384-394
-
-
Guo, Y.1
Wang, J.2
Niu, G.3
Shui, W.4
Sun, Y.5
Zhou, H.6
Zhang, Y.7
Yang, C.8
Lou, Z.9
Rao, Z.10
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