Synthesis of de novo designed small-molecule inhibitors of bacterial RNA polymerase

Tetrahedron

Volumn 64, Issue 43, 2008, Pages 10049-10054

  Agarwal, Anil K ^a   Johnson, A Peter ^a   Fishwick, Colin W G ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [(1 AMINO 1 OXO 3 PHENYLPROPAN 2 YLAMINO)METHYL] 3 (4 AMINOPHENOXY) 5 METHOXY PHENYLACETATE; 2 [(1 AMINO 1 OXO 3 PHENYLPROPAN 2 YLAMINO)METHYL] 5 METHOXY 3 (4 NITROPHENOXY)PHENYLACETATE; 2 [[1 AMINO 3 (4 HYDROXYPHENYL) 1 OXOPROPAN 2 YLAMINO]METHYL] 3 (4 AMINOPHENOXY) 5 METHOXY PHENYLACETATE; 2 [[1 AMINO 3 (4 HYDROXYPHENYL) 1 OXOPROPAN 2 YLAMINO]METHYL] 5 METHOXY 3 (4 NITROPHENOXY)PHENYLACETATE; ENZYME INHIBITOR; IMINE; RIFAMPICIN; RNA POLYMERASE; SULFILIMINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; HYDROGEN BOND; IC 50; PRIORITY JOURNAL; THERMUS AQUATICUS; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; THERMUS AQUATICUS;

EID: 50849135173     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.08.037     Document Type: Article

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