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Volumn 5, Issue JUL, 2014, Pages

Cancer stem cell immunology: Key to understanding tumorigenesis and tumor immune escape?

Author keywords

Cancer stem cell immunology; Cancer stem cells; Latency; Tumor dormancy; Tumor immune escape; Tumor immunology; Tumor immunosurveillance; Tumor propagating cells

Indexed keywords


EID: 84905639073     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00360     Document Type: Article
Times cited : (144)

References (170)
  • 2
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • doi: 10.1016/S0092-8674(00)81683-9
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell (2000) 100(1):57-70. doi: 10.1016/S0092-8674(00)81683-9
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 0014887939 scopus 로고
    • The concept of immunological surveillance
    • Burnet FM. The concept of immunological surveillance. Prog Exp Tumor Res (1970) 13:1-27.
    • (1970) Prog Exp Tumor Res , vol.13 , pp. 1-27
    • Burnet, F.M.1
  • 4
    • 68849105814 scopus 로고    scopus 로고
    • Oncogenic stress sensed by the immune system: role of natural killer cell receptors
    • doi:10.1038/nri2604
    • Raulet DH, Guerra N. Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat Rev Immunol (2009) 9(8):568-80. doi:10.1038/nri2604
    • (2009) Nat Rev Immunol , vol.9 , Issue.8 , pp. 568-580
    • Raulet, D.H.1    Guerra, N.2
  • 5
    • 84877035820 scopus 로고    scopus 로고
    • The repertoire of human tumor-associated epitopes - identification and selection of antigens and their application in clinical trials
    • doi:10.1016/j.coi.2013.03.007
    • Haen SP, Rammensee HG. The repertoire of human tumor-associated epitopes - identification and selection of antigens and their application in clinical trials. Curr Opin Immunol (2013) 25(2):277-83. doi:10.1016/j.coi.2013.03.007
    • (2013) Curr Opin Immunol , vol.25 , Issue.2 , pp. 277-283
    • Haen, S.P.1    Rammensee, H.G.2
  • 6
    • 74449085934 scopus 로고    scopus 로고
    • A small-cell lung cancer genome with complex signatures of tobacco exposure
    • doi:10.1038/nature08629
    • Pleasance ED, Stephens PJ, O'Meara S, McBride DJ, Meynert A, Jones D, et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature (2010) 463(7278):184-90. doi:10.1038/nature08629
    • (2010) Nature , vol.463 , Issue.7278 , pp. 184-190
    • Pleasance, E.D.1    Stephens, P.J.2    O'Meara, S.3    McBride, D.J.4    Meynert, A.5    Jones, D.6
  • 7
    • 77953006634 scopus 로고    scopus 로고
    • The mutation spectrum revealed by paired genome sequences from a lung cancer patient
    • doi:10.1038/nature09004
    • Lee W, Jiang Z, Liu J, Haverty PM, Guan Y, Stinson J, et al. The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature (2010) 465(7297):473-7. doi:10.1038/nature09004
    • (2010) Nature , vol.465 , Issue.7297 , pp. 473-477
    • Lee, W.1    Jiang, Z.2    Liu, J.3    Haverty, P.M.4    Guan, Y.5    Stinson, J.6
  • 8
    • 74449093973 scopus 로고    scopus 로고
    • A comprehensive catalogue of somatic mutations from a human cancer genome
    • doi:10.1038/nature08658
    • Pleasance ED, Cheetham RK, Stephens PJ, McBride DJ, Humphray SJ, Greenman CD, et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature (2010) 463(7278):191-6. doi:10.1038/nature08658
    • (2010) Nature , vol.463 , Issue.7278 , pp. 191-196
    • Pleasance, E.D.1    Cheetham, R.K.2    Stephens, P.J.3    McBride, D.J.4    Humphray, S.J.5    Greenman, C.D.6
  • 10
    • 79953059789 scopus 로고    scopus 로고
    • Natural innate and adaptive immunity to cancer
    • doi:10.1146/annurev-immunol-031210-101324
    • Vesely MD, Kershaw MH, Schreiber RD, Smyth MJ. Natural innate and adaptive immunity to cancer. Annu Rev Immunol (2011) 29:235-71. doi:10.1146/annurev-immunol-031210-101324
    • (2011) Annu Rev Immunol , vol.29 , pp. 235-271
    • Vesely, M.D.1    Kershaw, M.H.2    Schreiber, R.D.3    Smyth, M.J.4
  • 11
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • doi:10.1038/nri1936
    • Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol (2006) 6(10):715-27. doi:10.1038/nri1936
    • (2006) Nat Rev Immunol , vol.6 , Issue.10 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 12
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • doi:10.1038/35074122
    • Shankaran V, Ikeda H, Bruce AT, White JM, Swanson PE, Old LJ, et al. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature (2001) 410(6832):1107-11. doi:10.1038/35074122
    • (2001) Nature , vol.410 , Issue.6832 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6
  • 13
    • 36849010167 scopus 로고    scopus 로고
    • Adaptive immunity maintains occult cancer in an equilibrium state
    • doi:10.1038/nature06309
    • Koebel CM, Vermi W, Swann JB, Zerafa N, Rodig SJ, Old LJ, et al. Adaptive immunity maintains occult cancer in an equilibrium state. Nature (2007) 450(7171):903-7. doi:10.1038/nature06309
    • (2007) Nature , vol.450 , Issue.7171 , pp. 903-907
    • Koebel, C.M.1    Vermi, W.2    Swann, J.B.3    Zerafa, N.4    Rodig, S.J.5    Old, L.J.6
  • 14
    • 0029804782 scopus 로고    scopus 로고
    • Decreased tumor surveillance in perforin-deficient mice
    • doi:10.1084/jem.184.5.1781
    • van den Broek ME, Kagi D, Ossendorp F, Toes R, Vamvakas S, Lutz WK, et al. Decreased tumor surveillance in perforin-deficient mice. J Exp Med (1996) 184(5):1781-90. doi:10.1084/jem.184.5.1781
    • (1996) J Exp Med , vol.184 , Issue.5 , pp. 1781-1790
    • van den Broek, M.E.1    Kagi, D.2    Ossendorp, F.3    Toes, R.4    Vamvakas, S.5    Lutz, W.K.6
  • 15
    • 0034605122 scopus 로고    scopus 로고
    • Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma
    • doi:10.1084/jem.192.5.755
    • Smyth MJ, Thia KY, Street SE, MacGregor D, Godfrey DI, Trapani JA. Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med (2000) 192(5):755-60. doi:10.1084/jem.192.5.755
    • (2000) J Exp Med , vol.192 , Issue.5 , pp. 755-760
    • Smyth, M.J.1    Thia, K.Y.2    Street, S.E.3    MacGregor, D.4    Godfrey, D.I.5    Trapani, J.A.6
  • 16
    • 0035894946 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth
    • doi:10.1006/cimm.2001.1896
    • Takeda K, Smyth MJ, Cretney E, Hayakawa Y, Yamaguchi N, Yagita H, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth. Cell Immunol (2001) 214(2):194-200. doi:10.1006/cimm.2001.1896
    • (2001) Cell Immunol , vol.214 , Issue.2 , pp. 194-200
    • Takeda, K.1    Smyth, M.J.2    Cretney, E.3    Hayakawa, Y.4    Yamaguchi, N.5    Yagita, H.6
  • 17
    • 0037148518 scopus 로고    scopus 로고
    • Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
    • doi:10.1084/jem.20011171
    • Takeda K, Smyth MJ, Cretney E, Hayakawa Y, Kayagaki N, Yagita H, et al. Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J Exp Med (2002) 195(2):161-9. doi:10.1084/jem.20011171
    • (2002) J Exp Med , vol.195 , Issue.2 , pp. 161-169
    • Takeda, K.1    Smyth, M.J.2    Cretney, E.3    Hayakawa, Y.4    Kayagaki, N.5    Yagita, H.6
  • 18
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • doi:10.4049/jimmunol.168.3.1356
    • Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smyth MJ. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J Immunol (2002) 168(3):1356-61. doi:10.4049/jimmunol.168.3.1356
    • (2002) J Immunol , vol.168 , Issue.3 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 19
    • 0037226644 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer
    • Seki N, Hayakawa Y, Brooks AD, Wine J, Wiltrout RH, Yagita H, et al. Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer. Cancer Res (2003) 63(1):207-13.
    • (2003) Cancer Res , vol.63 , Issue.1 , pp. 207-213
    • Seki, N.1    Hayakawa, Y.2    Brooks, A.D.3    Wine, J.4    Wiltrout, R.H.5    Yagita, H.6
  • 20
    • 38149139518 scopus 로고    scopus 로고
    • TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis
    • doi:10.1172/JCI29900
    • Finnberg N, Klein-Szanto AJ, El-Deiry WS. TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. J Clin Invest (2008) 118(1):111-23. doi:10.1172/JCI29900
    • (2008) J Clin Invest , vol.118 , Issue.1 , pp. 111-123
    • Finnberg, N.1    Klein-Szanto, A.J.2    El-Deiry, W.S.3
  • 21
    • 49149108257 scopus 로고    scopus 로고
    • AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice
    • doi:10.1038/onc.2008.111
    • Nepal RM, Zaheen A, Basit W, Li L, Berger SA, Martin A. AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice. Oncogene (2008) 27(34):4752-6. doi:10.1038/onc.2008.111
    • (2008) Oncogene , vol.27 , Issue.34 , pp. 4752-4756
    • Nepal, R.M.1    Zaheen, A.2    Basit, W.3    Li, L.4    Berger, S.A.5    Martin, A.6
  • 22
    • 0035914134 scopus 로고    scopus 로고
    • Regulation of cutaneous malignancy by gammadelta T cells
    • doi:10.1126/science.1063916
    • Girardi M, Oppenheim DE, Steele CR, Lewis JM, Glusac E, Filler R, et al. Regulation of cutaneous malignancy by gammadelta T cells. Science (2001) 294(5542):605-9. doi:10.1126/science.1063916
    • (2001) Science , vol.294 , Issue.5542 , pp. 605-609
    • Girardi, M.1    Oppenheim, D.E.2    Steele, C.R.3    Lewis, J.M.4    Glusac, E.5    Filler, R.6
  • 23
    • 41549163195 scopus 로고    scopus 로고
    • NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
    • doi:10.1016/j.immuni.2008.02.016
    • Guerra N, Tan YX, Joncker NT, Choy A, Gallardo F, Xiong N, et al. NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity (2008) 28(4):571-80. doi:10.1016/j.immuni.2008.02.016
    • (2008) Immunity , vol.28 , Issue.4 , pp. 571-580
    • Guerra, N.1    Tan, Y.X.2    Joncker, N.T.3    Choy, A.4    Gallardo, F.5    Xiong, N.6
  • 24
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • doi:10.1016/j.cell.2011.02.013
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell (2011) 144(5):646-74. doi:10.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 25
    • 1942476133 scopus 로고    scopus 로고
    • Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients
    • doi:10.1097/00042728-200404020-00009
    • Ulrich C, Schmook T, Sachse MM, Sterry W, Stockfleth E. Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients. Dermatol Surg (2004) 30(4 Pt 2):622-7. doi:10.1097/00042728-200404020-00009
    • (2004) Dermatol Surg , vol.30 , Issue.4 PART 2 , pp. 622-627
    • Ulrich, C.1    Schmook, T.2    Sachse, M.M.3    Sterry, W.4    Stockfleth, E.5
  • 26
    • 0036789796 scopus 로고    scopus 로고
    • Malignancy after renal transplantation: incidence and role of type of immunosuppression
    • doi:10.1007/BF02574501
    • Tremblay F, Fernandes M, Habbab F, deB Edwardes MD, Loertscher R, Meterissian S. Malignancy after renal transplantation: incidence and role of type of immunosuppression. Ann Surg Oncol (2002) 9(8):785-8. doi:10.1007/BF02574501
    • (2002) Ann Surg Oncol , vol.9 , Issue.8 , pp. 785-788
    • Tremblay, F.1    Fernandes, M.2    Habbab, F.3    deB Edwardes, M.D.4    Loertscher, R.5    Meterissian, S.6
  • 27
    • 24644523670 scopus 로고    scopus 로고
    • Cancer incidence after immunosuppressive treatment following kidney transplantation
    • doi:10.1016/j.critrevonc.2004.11.010
    • Andres A. Cancer incidence after immunosuppressive treatment following kidney transplantation. Crit Rev Oncol Hematol (2005) 56(1):71-85. doi:10.1016/j.critrevonc.2004.11.010
    • (2005) Crit Rev Oncol Hematol , vol.56 , Issue.1 , pp. 71-85
    • Andres, A.1
  • 28
    • 0037393121 scopus 로고    scopus 로고
    • Immunosuppressive drugs and cancer
    • doi:10.1016/S0300-483X(02)00612-1
    • Vial T, Descotes J. Immunosuppressive drugs and cancer. Toxicology (2003) 185(3):229-40. doi:10.1016/S0300-483X(02)00612-1
    • (2003) Toxicology , vol.185 , Issue.3 , pp. 229-240
    • Vial, T.1    Descotes, J.2
  • 29
    • 0034973005 scopus 로고    scopus 로고
    • Epidemiology of AIDS-related tumours in developed and developing countries
    • doi:10.1016/S0959-8049(01)00120-4
    • Dal Maso L, Serraino D, Franceschi S. Epidemiology of AIDS-related tumours in developed and developing countries. Eur J Cancer (2001) 37(10):1188-201. doi:10.1016/S0959-8049(01)00120-4
    • (2001) Eur J Cancer , vol.37 , Issue.10 , pp. 1188-1201
    • Dal Maso, L.1    Serraino, D.2    Franceschi, S.3
  • 30
    • 0033883766 scopus 로고    scopus 로고
    • The epidemiology of acquired immunodeficiency syndrome malignancies
    • Goedert JJ. The epidemiology of acquired immunodeficiency syndrome malignancies. Semin Oncol (2000) 27(4):390-401.
    • (2000) Semin Oncol , vol.27 , Issue.4 , pp. 390-401
    • Goedert, J.J.1
  • 31
    • 29744464271 scopus 로고    scopus 로고
    • AIDS-related malignancies: changing epidemiology and the impact of highly active antiretroviral therapy
    • doi:10.1097/01.qco.0000200295.30285.13
    • Bower M, Palmieri C, Dhillon T. AIDS-related malignancies: changing epidemiology and the impact of highly active antiretroviral therapy. Curr Opin Infect Dis (2006) 19(1):14-9. doi:10.1097/01.qco.0000200295.30285.13
    • (2006) Curr Opin Infect Dis , vol.19 , Issue.1 , pp. 14-19
    • Bower, M.1    Palmieri, C.2    Dhillon, T.3
  • 32
    • 84876855721 scopus 로고    scopus 로고
    • How ageing processes influence cancer
    • doi:10.1038/nrc3497
    • de Magalhaes JP. How ageing processes influence cancer. Nat Rev Cancer (2013) 13(5):357-65. doi:10.1038/nrc3497
    • (2013) Nat Rev Cancer , vol.13 , Issue.5 , pp. 357-365
    • de Magalhaes, J.P.1
  • 33
    • 77249088142 scopus 로고    scopus 로고
    • The role of immunity in elderly cancer
    • doi:10.1016/j.critrevonc.2009.06.002
    • Malaguarnera L, Cristaldi E, Malaguarnera M. The role of immunity in elderly cancer. Crit Rev Oncol Hematol (2010) 74(1):40-60. doi:10.1016/j.critrevonc.2009.06.002
    • (2010) Crit Rev Oncol Hematol , vol.74 , Issue.1 , pp. 40-60
    • Malaguarnera, L.1    Cristaldi, E.2    Malaguarnera, M.3
  • 34
    • 77953205304 scopus 로고    scopus 로고
    • Potential role of immunosenescence in cancer development
    • doi:10.1111/j.1749-6632.2009.05370.x
    • Fulop T, Kotb R, Fortin CF, Pawelec G, de Angelis F, Larbi A. Potential role of immunosenescence in cancer development. Ann N Y Acad Sci (2010) 1197:158-65. doi:10.1111/j.1749-6632.2009.05370.x
    • (2010) Ann N Y Acad Sci , vol.1197 , pp. 158-165
    • Fulop, T.1    Kotb, R.2    Fortin, C.F.3    Pawelec, G.4    de Angelis, F.5    Larbi, A.6
  • 36
    • 84860524550 scopus 로고    scopus 로고
    • Spleen cells from young but not old immunized mice eradicate large established cancers
    • doi:10.1158/1078-0432.CCR-12-0127
    • Schreiber K, Arina A, Engels B, Spiotto MT, Sidney J, Sette A, et al. Spleen cells from young but not old immunized mice eradicate large established cancers. Clin Cancer Res (2012) 18(9):2526-33. doi:10.1158/1078-0432.CCR-12-0127
    • (2012) Clin Cancer Res , vol.18 , Issue.9 , pp. 2526-2533
    • Schreiber, K.1    Arina, A.2    Engels, B.3    Spiotto, M.T.4    Sidney, J.5    Sette, A.6
  • 37
    • 46949109577 scopus 로고    scopus 로고
    • Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness
    • doi:10.1084/jem.20072016
    • Willimsky G, Czeh M, Loddenkemper C, Gellermann J, Schmidt K, Wust P, et al. Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness. J Exp Med (2008) 205(7):1687-700. doi:10.1084/jem.20072016
    • (2008) J Exp Med , vol.205 , Issue.7 , pp. 1687-1700
    • Willimsky, G.1    Czeh, M.2    Loddenkemper, C.3    Gellermann, J.4    Schmidt, K.5    Wust, P.6
  • 38
    • 59649091694 scopus 로고    scopus 로고
    • Accelerated tumor growth in mice deficient in DNAM-1 receptor
    • doi:10.1084/jem.20081611
    • Iguchi-Manaka A, Kai H, Yamashita Y, Shibata K, Tahara-Hanaoka S, Honda S, et al. Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med (2008) 205(13):2959-64. doi:10.1084/jem.20081611
    • (2008) J Exp Med , vol.205 , Issue.13 , pp. 2959-2964
    • Iguchi-Manaka, A.1    Kai, H.2    Yamashita, Y.3    Shibata, K.4    Tahara-Hanaoka, S.5    Honda, S.6
  • 40
    • 84862776855 scopus 로고    scopus 로고
    • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
    • doi:10.1038/nature10755
    • Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, et al. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature (2012) 482(7385):400-4. doi:10.1038/nature10755
    • (2012) Nature , vol.482 , Issue.7385 , pp. 400-404
    • Matsushita, H.1    Vesely, M.D.2    Koboldt, D.C.3    Rickert, C.G.4    Uppaluri, R.5    Magrini, V.J.6
  • 41
    • 84857118418 scopus 로고    scopus 로고
    • Expression of tumour-specific antigens underlies cancer immunoediting
    • doi:10.1038/nature10803
    • DuPage M, Mazumdar C, Schmidt LM, Cheung AF, Jacks T. Expression of tumour-specific antigens underlies cancer immunoediting. Nature (2012) 482(7385):405-9. doi:10.1038/nature10803
    • (2012) Nature , vol.482 , Issue.7385 , pp. 405-409
    • DuPage, M.1    Mazumdar, C.2    Schmidt, L.M.3    Cheung, A.F.4    Jacks, T.5
  • 42
    • 51649121390 scopus 로고    scopus 로고
    • Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands
    • doi:10.1111/j.1399-0039.2008.01106.x
    • Campoli M, Ferrone S. Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands. Tissue Antigens (2008) 72(4):321-34. doi:10.1111/j.1399-0039.2008.01106.x
    • (2008) Tissue Antigens , vol.72 , Issue.4 , pp. 321-334
    • Campoli, M.1    Ferrone, S.2
  • 43
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • doi:10.1016/j.immuni.2004.07.017
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity (2004) 21(2):137-48. doi:10.1016/j.immuni.2004.07.017
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 44
    • 34047220868 scopus 로고    scopus 로고
    • Cancer immunoediting from immune surveillance to immune escape
    • doi:10.1111/j.1365-2567.2007.02587.x
    • Kim R, Emi M, Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology (2007) 121(1):1-14. doi:10.1111/j.1365-2567.2007.02587.x
    • (2007) Immunology , vol.121 , Issue.1 , pp. 1-14
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 45
    • 34547655817 scopus 로고    scopus 로고
    • Tumor immunoediting and immunosculpting pathways to cancer progression
    • doi:10.1016/j.semcancer.2007.06.009
    • Reiman JM, Kmieciak M, Manjili MH, Knutson KL. Tumor immunoediting and immunosculpting pathways to cancer progression. Semin Cancer Biol (2007) 17(4):275-87. doi:10.1016/j.semcancer.2007.06.009
    • (2007) Semin Cancer Biol , vol.17 , Issue.4 , pp. 275-287
    • Reiman, J.M.1    Kmieciak, M.2    Manjili, M.H.3    Knutson, K.L.4
  • 46
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • doi:10.1038/nature04372
    • Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, et al. Generation of a functional mammary gland from a single stem cell. Nature (2006) 439(7072):84-8. doi:10.1038/nature04372
    • (2006) Nature , vol.439 , Issue.7072 , pp. 84-88
    • Shackleton, M.1    Vaillant, F.2    Simpson, K.J.3    Stingl, J.4    Smyth, G.K.5    Asselin-Labat, M.L.6
  • 47
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • doi:10.1038/nature04496
    • Stingl J, Eirew P, Ricketson I, Shackleton M, Vaillant F, Choi D, et al. Purification and unique properties of mammary epithelial stem cells. Nature (2006) 439(7079):993-7. doi:10.1038/nature04496
    • (2006) Nature , vol.439 , Issue.7079 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3    Shackleton, M.4    Vaillant, F.5    Choi, D.6
  • 48
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cancer
    • doi:10.1016/j.cell.2005.03.032
    • Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell (2005) 121(6):823-35. doi:10.1016/j.cell.2005.03.032
    • (2005) Cell , vol.121 , Issue.6 , pp. 823-835
    • Kim, C.F.1    Jackson, E.L.2    Woolfenden, A.E.3    Lawrence, S.4    Babar, I.5    Vogel, S.6
  • 49
    • 33846065145 scopus 로고    scopus 로고
    • Isolation and functional characterization of murine prostate stem cells
    • doi:10.1073/pnas.0609684104
    • Lawson DA, Xin L, Lukacs RU, Cheng D, Witte ON. Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci U S A (2007) 104(1):181-6. doi:10.1073/pnas.0609684104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.1 , pp. 181-186
    • Lawson, D.A.1    Xin, L.2    Lukacs, R.U.3    Cheng, D.4    Witte, O.N.5
  • 50
    • 0035177262 scopus 로고    scopus 로고
    • Identification and isolation of human prostate epithelial stem cells based on alpha(2)beta(1)-integrin expression
    • Collins AT, Habib FK, Maitland NJ, Neal DE. Identification and isolation of human prostate epithelial stem cells based on alpha(2)beta(1)-integrin expression. J Cell Sci (2001) 114(Pt 21):3865-72.
    • (2001) J Cell Sci , vol.114 , Issue.PART 21 , pp. 3865-3872
    • Collins, A.T.1    Habib, F.K.2    Maitland, N.J.3    Neal, D.E.4
  • 51
    • 4444262529 scopus 로고    scopus 로고
    • CD133, a novel marker for human prostatic epithelial stem cells
    • doi:10.1242/jcs.01222
    • Richardson GD, Robson CN, Lang SH, Neal DE, Maitland NJ, Collins AT. CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci (2004) 117(Pt 16):3539-45. doi:10.1242/jcs.01222
    • (2004) J Cell Sci , vol.117 , Issue.PART 16 , pp. 3539-3545
    • Richardson, G.D.1    Robson, C.N.2    Lang, S.H.3    Neal, D.E.4    Maitland, N.J.5    Collins, A.T.6
  • 52
    • 35548974423 scopus 로고    scopus 로고
    • Identification of stem cells in small intestine and colon by marker gene Lgr5
    • doi:10.1038/nature06196
    • Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature (2007) 449(7165):1003-7. doi:10.1038/nature06196
    • (2007) Nature , vol.449 , Issue.7165 , pp. 1003-1007
    • Barker, N.1    van Es, J.H.2    Kuipers, J.3    Kujala, P.4    van den Born, M.5    Cozijnsen, M.6
  • 53
    • 0025163541 scopus 로고
    • Stem-cell organization in mouse small intestine
    • doi:10.1098/rspb.1990.0059
    • Winton DJ, Ponder BA. Stem-cell organization in mouse small intestine. Proc Biol Sci (1990) 241(1300):13-8. doi:10.1098/rspb.1990.0059
    • (1990) Proc Biol Sci , vol.241 , Issue.1300 , pp. 13-18
    • Winton, D.J.1    Ponder, B.A.2
  • 54
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: a balancing act of stem cells in the skin
    • doi:10.1038/nrm2636
    • Blanpain C, Fuchs E. Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 10(3):207-17. doi:10.1038/nrm2636
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.3 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 55
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • doi:10.1038/35102167
    • Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature (2001) 414(6859):105-11. doi:10.1038/35102167
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 56
    • 0034303586 scopus 로고    scopus 로고
    • Diversification of haematopoietic stem cells to specific lineages
    • doi:10.1038/35049577
    • Orkin SH. Diversification of haematopoietic stem cells to specific lineages. Nat Rev Genet (2000) 1(1):57-64. doi:10.1038/35049577
    • (2000) Nat Rev Genet , vol.1 , Issue.1 , pp. 57-64
    • Orkin, S.H.1
  • 57
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • doi:10.1084/jem.20050967
    • Passegue E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med (2005) 202(11):1599-611. doi:10.1084/jem.20050967
    • (2005) J Exp Med , vol.202 , Issue.11 , pp. 1599-1611
    • Passegue, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 58
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: units of development, units of regeneration, and units in evolution
    • doi:10.1016/S0092-8674(00)81692-X
    • Weissman IL. Stem cells: units of development, units of regeneration, and units in evolution. Cell (2000) 100(1):157-68. doi:10.1016/S0092-8674(00)81692-X
    • (2000) Cell , vol.100 , Issue.1 , pp. 157-168
    • Weissman, I.L.1
  • 59
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • doi:10.1016/j.cell.2008.10.048
    • Wilson A, Laurenti E, Oser G, van der Wath RC, Blanco-Bose W, Jaworski M, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell (2008) 135(6):1118-29. doi:10.1016/j.cell.2008.10.048
    • (2008) Cell , vol.135 , Issue.6 , pp. 1118-1129
    • Wilson, A.1    Laurenti, E.2    Oser, G.3    van der Wath, R.C.4    Blanco-Bose, W.5    Jaworski, M.6
  • 60
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • doi:10.1126/science.959840
    • Nowell PC. The clonal evolution of tumor cell populations. Science (1976) 194(4260):23-8. doi:10.1126/science.959840
    • (1976) Science , vol.194 , Issue.4260 , pp. 23-28
    • Nowell, P.C.1
  • 61
    • 0014524550 scopus 로고
    • The two "hit" and multiple "hit" theories of carcinogenesis
    • doi:10.1038/bjc.1969.41
    • Ashley DJ. The two "hit" and multiple "hit" theories of carcinogenesis. Br J Cancer (1969) 23(2):313-28. doi:10.1038/bjc.1969.41
    • (1969) Br J Cancer , vol.23 , Issue.2 , pp. 313-328
    • Ashley, D.J.1
  • 62
    • 84908007911 scopus 로고
    • A new theory on cancer-inducing mechanism
    • doi:10.1038/bjc.1953.8
    • Nordling CO. A new theory on cancer-inducing mechanism. Br J Cancer (1953) 7(1):68-72. doi:10.1038/bjc.1953.8
    • (1953) Br J Cancer , vol.7 , Issue.1 , pp. 68-72
    • Nordling, C.O.1
  • 63
    • 84883845299 scopus 로고
    • Multipotentiality of single embryonal carcinoma cells
    • Kleinsmith LJ, Pierce GB Jr. Multipotentiality of single embryonal carcinoma cells. Cancer Res (1964) 24:1544-51.
    • (1964) Cancer Res , vol.24 , pp. 1544-1551
    • Kleinsmith, L.J.1    Pierce Jr, G.B.2
  • 64
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • doi:10.1038/nm0901-1028
    • Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med (2001) 7(9):1028-34. doi:10.1038/nm0901-1028
    • (2001) Nat Med , vol.7 , Issue.9 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3    Colapietro, A.M.4    Sampath, J.5    Morris, J.J.6
  • 65
    • 84864146822 scopus 로고    scopus 로고
    • Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and miscrosatellite instability
    • doi:10.1182/blood-2011-10-388629
    • Shlush LI, Chapal-Ilani N, Adar R, Pery N, Maruvka Y, Spiro A, et al. Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and miscrosatellite instability. Blood (2012) 120(3):603-12. doi:10.1182/blood-2011-10-388629
    • (2012) Blood , vol.120 , Issue.3 , pp. 603-612
    • Shlush, L.I.1    Chapal-Ilani, N.2    Adar, R.3    Pery, N.4    Maruvka, Y.5    Spiro, A.6
  • 66
    • 0025799513 scopus 로고
    • Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
    • doi:10.1016/0092-8674(91)90141-K
    • Chaudhary PM, Roninson IB. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell (1991) 66(1):85-94. doi:10.1016/0092-8674(91)90141-K
    • (1991) Cell , vol.66 , Issue.1 , pp. 85-94
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 67
    • 78649887674 scopus 로고    scopus 로고
    • Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging
    • doi:10.1098/rsif.2010.0353.focus
    • Kooreman NG, Wu JC. Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging. J R Soc Interface (2010) 7(Suppl 6):S753-63. doi:10.1098/rsif.2010.0353.focus
    • (2010) J R Soc Interface , vol.7 , Issue.SUPPL. 6
    • Kooreman, N.G.1    Wu, J.C.2
  • 68
    • 33646428091 scopus 로고    scopus 로고
    • Normal stem cells and cancer stem cells: the niche matters
    • doi:10.1158/0008-5472.CAN-05-3986
    • Li L, Neaves WB. Normal stem cells and cancer stem cells: the niche matters. Cancer Res (2006) 66(9):4553-7. doi:10.1158/0008-5472.CAN-05-3986
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4553-4557
    • Li, L.1    Neaves, W.B.2
  • 69
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • doi:10.1038/nm.2000
    • Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med (2009) 15(8):907-13. doi:10.1038/nm.2000
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 907-913
    • Lim, E.1    Vaillant, F.2    Wu, D.3    Forrest, N.C.4    Pal, B.5    Hart, A.H.6
  • 70
    • 77956218241 scopus 로고    scopus 로고
    • BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
    • doi:10.1016/j.stem.2010.07.010
    • Molyneux G, Geyer FC, Magnay FA, McCarthy A, Kendrick H, Natrajan R, et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell (2010) 7(3):403-17. doi:10.1016/j.stem.2010.07.010
    • (2010) Cell Stem Cell , vol.7 , Issue.3 , pp. 403-417
    • Molyneux, G.1    Geyer, F.C.2    Magnay, F.A.3    McCarthy, A.4    Kendrick, H.5    Natrajan, R.6
  • 71
    • 77955121375 scopus 로고    scopus 로고
    • Identification of a cell of origin for human prostate cancer
    • doi:10.1126/science.1189992
    • Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON. Identification of a cell of origin for human prostate cancer. Science (2010) 329(5991):568-71. doi:10.1126/science.1189992
    • (2010) Science , vol.329 , Issue.5991 , pp. 568-571
    • Goldstein, A.S.1    Huang, J.2    Guo, C.3    Garraway, I.P.4    Witte, O.N.5
  • 72
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells - perspectives on current status and future directions: AACR Workshop on cancer stem cells
    • doi:10.1158/0008-5472.CAN-06-3126
    • Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, et al. Cancer stem cells - perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res (2006) 66(19):9339-44. doi:10.1158/0008-5472.CAN-06-3126
    • (2006) Cancer Res , vol.66 , Issue.19 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.5    Jones, D.L.6
  • 73
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • doi:10.1016/j.cell.2006.07.024
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 126(4):663-76. doi:10.1016/j.cell.2006.07.024
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 74
    • 79956351015 scopus 로고    scopus 로고
    • Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
    • doi:10.1073/pnas.1102454108
    • Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci U S A (2011) 108(19):7950-5. doi:10.1073/pnas.1102454108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.19 , pp. 7950-7955
    • Chaffer, C.L.1    Brueckmann, I.2    Scheel, C.3    Kaestli, A.J.4    Wiggins, P.A.5    Rodrigues, L.O.6
  • 75
    • 66149131111 scopus 로고    scopus 로고
    • Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells
    • doi:10.1158/0008-5472.CAN-08-3343
    • Santisteban M, Reiman JM, Asiedu MK, Behrens MD, Nassar A, Kalli KR, et al. Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells. Cancer Res (2009) 69(7):2887-95. doi:10.1158/0008-5472.CAN-08-3343
    • (2009) Cancer Res , vol.69 , Issue.7 , pp. 2887-2895
    • Santisteban, M.1    Reiman, J.M.2    Asiedu, M.K.3    Behrens, M.D.4    Nassar, A.5    Kalli, K.R.6
  • 76
    • 34247500441 scopus 로고    scopus 로고
    • Transforming growth factor alpha promotes sequential conversion of mature astrocytes into neural progenitors and stem cells
    • doi:10.1038/sj.onc.1210071
    • Sharif A, Legendre P, Prevot V, Allet C, Romao L, Studler JM, et al. Transforming growth factor alpha promotes sequential conversion of mature astrocytes into neural progenitors and stem cells. Oncogene (2007) 26(19):2695-706. doi:10.1038/sj.onc.1210071
    • (2007) Oncogene , vol.26 , Issue.19 , pp. 2695-2706
    • Sharif, A.1    Legendre, P.2    Prevot, V.3    Allet, C.4    Romao, L.5    Studler, J.M.6
  • 77
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • doi:10.1016/j.cell.2011.07.026
    • Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell (2011) 146(4):633-44. doi:10.1016/j.cell.2011.07.026
    • (2011) Cell , vol.146 , Issue.4 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3    Shapira, S.D.4    Tao, K.5    Kuperwasser, C.6
  • 78
    • 84867685827 scopus 로고    scopus 로고
    • Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation
    • doi:10.1038/nature11538
    • Landsberg J, Kohlmeyer J, Renn M, Bald T, Rogava M, Cron M, et al. Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation. Nature (2012) 490(7420):412-6. doi:10.1038/nature11538
    • (2012) Nature , vol.490 , Issue.7420 , pp. 412-416
    • Landsberg, J.1    Kohlmeyer, J.2    Renn, M.3    Bald, T.4    Rogava, M.5    Cron, M.6
  • 79
    • 84896498641 scopus 로고    scopus 로고
    • VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation
    • doi:10.1158/0008-5472.CAN-13-1641
    • Fantozzi A, Gruber DC, Pisarsky L, Heck C, Kunita A, Yilmaz M, et al. VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation. Cancer Res (2014) 74(5):1566-75. doi:10.1158/0008-5472.CAN-13-1641
    • (2014) Cancer Res , vol.74 , Issue.5 , pp. 1566-1575
    • Fantozzi, A.1    Gruber, D.C.2    Pisarsky, L.3    Heck, C.4    Kunita, A.5    Yilmaz, M.6
  • 80
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • doi:10.1038/nrm3758
    • Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol (2014) 15(3):178-96. doi:10.1038/nrm3758
    • (2014) Nat Rev Mol Cell Biol , vol.15 , Issue.3 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 81
    • 84887273608 scopus 로고    scopus 로고
    • Epithelial plasticity: a common theme in embryonic and cancer cells
    • doi:10.1126/science.1234850
    • Nieto MA. Epithelial plasticity: a common theme in embryonic and cancer cells. Science (2013) 342(6159):1234850. doi:10.1126/science.1234850
    • (2013) Science , vol.342 , Issue.6159 , pp. 1234850
    • Nieto, M.A.1
  • 82
    • 27144557960 scopus 로고    scopus 로고
    • A tumorigenic subpopulation with stem cell properties in melanomas
    • doi:10.1158/0008-5472.CAN-05-1343
    • Fang D, Nguyen TK, Leishear K, Finko R, Kulp AN, Hotz S, et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res (2005) 65(20):9328-37. doi:10.1158/0008-5472.CAN-05-1343
    • (2005) Cancer Res , vol.65 , Issue.20 , pp. 9328-9337
    • Fang, D.1    Nguyen, T.K.2    Leishear, K.3    Finko, R.4    Kulp, A.N.5    Hotz, S.6
  • 83
    • 33847639310 scopus 로고    scopus 로고
    • Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential
    • doi:10.1016/j.ejca.2007.01.017
    • Monzani E, Facchetti F, Galmozzi E, Corsini E, Benetti A, Cavazzin C, et al. Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential. Eur J Cancer (2007) 43(5):935-46. doi:10.1016/j.ejca.2007.01.017
    • (2007) Eur J Cancer , vol.43 , Issue.5 , pp. 935-946
    • Monzani, E.1    Facchetti, F.2    Galmozzi, E.3    Corsini, E.4    Benetti, A.5    Cavazzin, C.6
  • 85
    • 77954238710 scopus 로고    scopus 로고
    • Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
    • doi:10.1038/nature09161
    • Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP, et al. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature (2010) 466(7302):133-7. doi:10.1038/nature09161
    • (2010) Nature , vol.466 , Issue.7302 , pp. 133-137
    • Boiko, A.D.1    Razorenova, O.V.2    van de Rijn, M.3    Swetter, S.M.4    Johnson, D.L.5    Ly, D.P.6
  • 86
    • 69949129056 scopus 로고    scopus 로고
    • Cancer stem cells: mirage or reality?
    • doi:10.1038/nm0909-1010
    • Gupta PB, Chaffer CL, Weinberg RA. Cancer stem cells: mirage or reality? Nat Med (2009) 15(9):1010-2. doi:10.1038/nm0909-1010
    • (2009) Nat Med , vol.15 , Issue.9 , pp. 1010-1012
    • Gupta, P.B.1    Chaffer, C.L.2    Weinberg, R.A.3
  • 87
    • 57349126306 scopus 로고    scopus 로고
    • Cancer stem cells: here, there, everywhere?
    • doi:10.1038/456581a
    • Eaves CJ. Cancer stem cells: here, there, everywhere? Nature (2008) 456(7222):581-2. doi:10.1038/456581a
    • (2008) Nature , vol.456 , Issue.7222 , pp. 581-582
    • Eaves, C.J.1
  • 88
    • 59249092827 scopus 로고    scopus 로고
    • Cancer stem cells are everywhere
    • doi:10.1038/nm0109-23
    • Passegue E, Rafii S, Herlyn M. Cancer stem cells are everywhere. Nat Med (2009) 15(1):23. doi:10.1038/nm0109-23
    • (2009) Nat Med , vol.15 , Issue.1 , pp. 23
    • Passegue, E.1    Rafii, S.2    Herlyn, M.3
  • 89
    • 57349143739 scopus 로고    scopus 로고
    • Efficient tumour formation by single human melanoma cells
    • doi:10.1038/nature07567
    • Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ. Efficient tumour formation by single human melanoma cells. Nature (2008) 456(7222):593-8. doi:10.1038/nature07567
    • (2008) Nature , vol.456 , Issue.7222 , pp. 593-598
    • Quintana, E.1    Shackleton, M.2    Sabel, M.S.3    Fullen, D.R.4    Johnson, T.M.5    Morrison, S.J.6
  • 90
    • 78249250559 scopus 로고    scopus 로고
    • Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
    • doi:10.1016/j.ccr.2010.10.012
    • Quintana E, Shackleton M, Foster HR, Fullen DR, Sabel MS, Johnson TM, et al. Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell (2010) 18(5):510-23. doi:10.1016/j.ccr.2010.10.012
    • (2010) Cancer Cell , vol.18 , Issue.5 , pp. 510-523
    • Quintana, E.1    Shackleton, M.2    Foster, H.R.3    Fullen, D.R.4    Sabel, M.S.5    Johnson, T.M.6
  • 91
    • 84877057303 scopus 로고    scopus 로고
    • Mechanisms of chemoresistance in cancer stem cells
    • doi:10.1186/2001-1326-2-3
    • Abdullah LN, Chow EK. Mechanisms of chemoresistance in cancer stem cells. Clin Transl Med (2013) 2(1):3. doi:10.1186/2001-1326-2-3
    • (2013) Clin Transl Med , vol.2 , Issue.1 , pp. 3
    • Abdullah, L.N.1    Chow, E.K.2
  • 92
    • 84903748693 scopus 로고    scopus 로고
    • Cancer stem cells in prostate cancer chemoresistance
    • doi:10.2174/1568009614666140328152459
    • Ni J, Cozzi P, Hao J, Duan W, Graham P, Kearsley J, et al. Cancer stem cells in prostate cancer chemoresistance. Curr Cancer Drug Targets (2014) 14(3):225-40. doi:10.2174/1568009614666140328152459
    • (2014) Curr Cancer Drug Targets , vol.14 , Issue.3 , pp. 225-240
    • Ni, J.1    Cozzi, P.2    Hao, J.3    Duan, W.4    Graham, P.5    Kearsley, J.6
  • 93
    • 57149109138 scopus 로고    scopus 로고
    • ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway
    • doi:10.1158/0008-5472.CAN-08-0719
    • Hamai A, Meslin F, Benlalam H, Jalil A, Mehrpour M, Faure F, et al. ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway. Cancer Res (2008) 68(23):9854-64. doi:10.1158/0008-5472.CAN-08-0719
    • (2008) Cancer Res , vol.68 , Issue.23 , pp. 9854-9864
    • Hamai, A.1    Meslin, F.2    Benlalam, H.3    Jalil, A.4    Mehrpour, M.5    Faure, F.6
  • 94
    • 0037945211 scopus 로고    scopus 로고
    • HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells
    • doi:10.1038/sj.onc.1206394
    • Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, et al. HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Oncogene (2003) 22(21):3205-12. doi:10.1038/sj.onc.1206394
    • (2003) Oncogene , vol.22 , Issue.21 , pp. 3205-3212
    • Knuefermann, C.1    Lu, Y.2    Liu, B.3    Jin, W.4    Liang, K.5    Wu, L.6
  • 95
    • 84886949455 scopus 로고    scopus 로고
    • The two sides of HER2/neu: immune escape versus surveillance
    • doi:10.1016/j.molmed.2013.08.003
    • Seliger B, Kiessling R. The two sides of HER2/neu: immune escape versus surveillance. Trends Mol Med (2013) 19(11):677-84. doi:10.1016/j.molmed.2013.08.003
    • (2013) Trends Mol Med , vol.19 , Issue.11 , pp. 677-684
    • Seliger, B.1    Kiessling, R.2
  • 96
    • 84890325511 scopus 로고    scopus 로고
    • The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer
    • doi:10.4049/jimmunol.1301597
    • Mimura K, Shiraishi K, Mueller A, Izawa S, Kua LF, So J, et al. The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer. J Immunol (2013) 191(12):6261-72. doi:10.4049/jimmunol.1301597
    • (2013) J Immunol , vol.191 , Issue.12 , pp. 6261-6272
    • Mimura, K.1    Shiraishi, K.2    Mueller, A.3    Izawa, S.4    Kua, L.F.5    So, J.6
  • 97
    • 84874857331 scopus 로고    scopus 로고
    • HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab
    • doi:10.1158/0008-5472.CAN-12-3349
    • Ithimakin S, Day KC, Malik F, Zen Q, Dawsey SJ, Bersano-Begey TF, et al. HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab. Cancer Res (2013) 73(5):1635-46. doi:10.1158/0008-5472.CAN-12-3349
    • (2013) Cancer Res , vol.73 , Issue.5 , pp. 1635-1646
    • Ithimakin, S.1    Day, K.C.2    Malik, F.3    Zen, Q.4    Dawsey, S.J.5    Bersano-Begey, T.F.6
  • 98
    • 70349552398 scopus 로고    scopus 로고
    • Antitumor immunity and cancer stem cells
    • doi:10.1111/j.1749-6632.2009.04568.x
    • Schatton T, Frank MH. Antitumor immunity and cancer stem cells. Ann N Y Acad Sci (2009) 1176:154-69. doi:10.1111/j.1749-6632.2009.04568.x
    • (2009) Ann N Y Acad Sci , vol.1176 , pp. 154-169
    • Schatton, T.1    Frank, M.H.2
  • 99
    • 70350238323 scopus 로고    scopus 로고
    • Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells
    • doi:10.1158/0008-5472.CAN-09-0834
    • Reim F, Dombrowski Y, Ritter C, Buttmann M, Häusler S, Ossadnik M, et al. Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells. Cancer Res (2009) 69(20):8058-66. doi:10.1158/0008-5472.CAN-09-0834
    • (2009) Cancer Res , vol.69 , Issue.20 , pp. 8058-8066
    • Reim, F.1    Dombrowski, Y.2    Ritter, C.3    Buttmann, M.4    Häusler, S.5    Ossadnik, M.6
  • 100
    • 76049114698 scopus 로고    scopus 로고
    • Immunobiological characterization of cancer stem cells isolated from glioblastoma patients
    • doi:10.1158/1078-0432.CCR-09-2730
    • Di Tomaso T, Mazzoleni S, Wang E, Sovena G, Clavenna D, Franzin A, et al. Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin Cancer Res (2010) 16(3):800-13. doi:10.1158/1078-0432.CCR-09-2730
    • (2010) Clin Cancer Res , vol.16 , Issue.3 , pp. 800-813
    • Di Tomaso, T.1    Mazzoleni, S.2    Wang, E.3    Sovena, G.4    Clavenna, D.5    Franzin, A.6
  • 101
    • 41049111969 scopus 로고    scopus 로고
    • Cancer stem cells and human malignant melanoma
    • doi:10.1111/j.1755-148X.2007.00427.x
    • Schatton T, Frank MH. Cancer stem cells and human malignant melanoma. Pigment Cell Melanoma Res (2008) 21(1):39-55. doi:10.1111/j.1755-148X.2007.00427.x
    • (2008) Pigment Cell Melanoma Res , vol.21 , Issue.1 , pp. 39-55
    • Schatton, T.1    Frank, M.H.2
  • 103
    • 77950221879 scopus 로고    scopus 로고
    • Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin
    • doi:10.1158/0008-5472.CAN-09-1707
    • Lottaz C, Beier D, Meyer K, Kumar P, Hermann A, Schwarz J, et al. Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer Res (2010) 70(5):2030-40. doi:10.1158/0008-5472.CAN-09-1707
    • (2010) Cancer Res , vol.70 , Issue.5 , pp. 2030-2040
    • Lottaz, C.1    Beier, D.2    Meyer, K.3    Kumar, P.4    Hermann, A.5    Schwarz, J.6
  • 104
    • 34848866647 scopus 로고    scopus 로고
    • Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
    • doi:10.1016/j.stem.2007.08.001
    • Todaro M, Alea MP, Di Stefano AB, Cammareri P, Vermeulen L, Iovino F, et al. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. Cell Stem Cell (2007) 1(4):389-402. doi:10.1016/j.stem.2007.08.001
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 389-402
    • Todaro, M.1    Alea, M.P.2    Di Stefano, A.B.3    Cammareri, P.4    Vermeulen, L.5    Iovino, F.6
  • 105
    • 31544460734 scopus 로고    scopus 로고
    • Tumor-derived interleukin-4 reduces tumor clearance and deviates the cytokine and granzyme profile of tumor-induced CD8+ T cells
    • doi:10.1158/0008-5472.CAN-05-1362
    • Olver S, Groves P, Buttigieg K, Morris ES, Janas ML, Kelso A, et al. Tumor-derived interleukin-4 reduces tumor clearance and deviates the cytokine and granzyme profile of tumor-induced CD8+ T cells. Cancer Res (2006) 66(1):571-80. doi:10.1158/0008-5472.CAN-05-1362
    • (2006) Cancer Res , vol.66 , Issue.1 , pp. 571-580
    • Olver, S.1    Groves, P.2    Buttigieg, K.3    Morris, E.S.4    Janas, M.L.5    Kelso, A.6
  • 106
    • 36148958993 scopus 로고    scopus 로고
    • Co-expression of the toleragenic glycoprotein, CD200, with markers for cancer stem cells
    • doi:10.1016/j.bbrc.2007.10.067
    • Kawasaki BT, Mistree T, Hurt EM, Kalathur M, Farrar WL. Co-expression of the toleragenic glycoprotein, CD200, with markers for cancer stem cells. Biochem Biophys Res Commun (2007) 364(4):778-82. doi:10.1016/j.bbrc.2007.10.067
    • (2007) Biochem Biophys Res Commun , vol.364 , Issue.4 , pp. 778-782
    • Kawasaki, B.T.1    Mistree, T.2    Hurt, E.M.3    Kalathur, M.4    Farrar, W.L.5
  • 107
    • 52249118343 scopus 로고    scopus 로고
    • Cancer stem cells CD200 and immunoevasion
    • doi:10.1016/j.it.2008.07.005
    • Kawasaki BT, Farrar WL. Cancer stem cells, CD200 and immunoevasion. Trends Immunol (2008) 29(10):464-8. doi:10.1016/j.it.2008.07.005
    • (2008) Trends Immunol , vol.29 , Issue.10 , pp. 464-468
    • Kawasaki, B.T.1    Farrar, W.L.2
  • 108
    • 34247639475 scopus 로고    scopus 로고
    • CD200 expression on tumor cells suppresses antitumor immunity: new approaches to cancer immunotherapy
    • doi:10.4049/jimmunol.178.9.5595
    • Kretz-Rommel A, Qin F, Dakappagari N, Ravey EP, McWhirter J, Oltean D, et al. CD200 expression on tumor cells suppresses antitumor immunity: new approaches to cancer immunotherapy. J Immunol (2007) 178(9):5595-605. doi:10.4049/jimmunol.178.9.5595
    • (2007) J Immunol , vol.178 , Issue.9 , pp. 5595-5605
    • Kretz-Rommel, A.1    Qin, F.2    Dakappagari, N.3    Ravey, E.P.4    McWhirter, J.5    Oltean, D.6
  • 109
    • 84893642085 scopus 로고    scopus 로고
    • Immunology of cancer stem cells in solid tumours
    • doi:10.1016/j.ejca.2013.11.014
    • Maccalli C, Volonte A, Cimminiello C, Parmiani G. Immunology of cancer stem cells in solid tumours. A review. Eur J Cancer (2014) 50(3):649-55. doi:10.1016/j.ejca.2013.11.014
    • (2014) A review. Eur J Cancer , vol.50 , Issue.3 , pp. 649-655
    • Maccalli, C.1    Volonte, A.2    Cimminiello, C.3    Parmiani, G.4
  • 110
    • 0037162551 scopus 로고    scopus 로고
    • Characterization of the expression of MHC proteins in human embryonic stem cells
    • doi:10.1073/pnas.142298299
    • Drukker M, Katz G, Urbach A, Schuldiner M, Markel G, Itskovitz-Eldor J, et al. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 99(15):9864-9. doi:10.1073/pnas.142298299
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.15 , pp. 9864-9869
    • Drukker, M.1    Katz, G.2    Urbach, A.3    Schuldiner, M.4    Markel, G.5    Itskovitz-Eldor, J.6
  • 111
    • 34247274772 scopus 로고    scopus 로고
    • Functions of HLA-G in the immune system
    • doi:10.1111/j.1399-0039.2006.763_6.x
    • Favier B, LeMaoult J, Carosella ED. Functions of HLA-G in the immune system. Tissue Antigens (2007) 69(Suppl 1):150-2. doi:10.1111/j.1399-0039.2006.763_6.x
    • (2007) Tissue Antigens , vol.69 , Issue.SUPPL 1 , pp. 150-152
    • Favier, B.1    LeMaoult, J.2    Carosella, E.D.3
  • 112
    • 79951834883 scopus 로고    scopus 로고
    • HLA-G expression in human embryonic stem cells and preimplantation embryos
    • doi:10.4049/jimmunol.1001081
    • Verloes A, Van de Velde H, LeMaoult J, Mateizel I, Cauffman G, Horn PA, et al. HLA-G expression in human embryonic stem cells and preimplantation embryos. J Immunol (2011) 186(4):2663-71. doi:10.4049/jimmunol.1001081
    • (2011) J Immunol , vol.186 , Issue.4 , pp. 2663-2671
    • Verloes, A.1    Van de Velde, H.2    LeMaoult, J.3    Mateizel, I.4    Cauffman, G.5    Horn, P.A.6
  • 113
    • 34547647603 scopus 로고    scopus 로고
    • Immunosuppressive effects of mesenchymal stem cells: involvement of HLA-G
    • doi:10.1097/01.tp.0000267918.07906.08
    • Nasef A, Mathieu N, Chapel A, Frick J, Francois S, Mazurier C, et al. Immunosuppressive effects of mesenchymal stem cells: involvement of HLA-G. Transplantation (2007) 84(2):231-7. doi:10.1097/01.tp.0000267918.07906.08
    • (2007) Transplantation , vol.84 , Issue.2 , pp. 231-237
    • Nasef, A.1    Mathieu, N.2    Chapel, A.3    Frick, J.4    Francois, S.5    Mazurier, C.6
  • 114
    • 2342557037 scopus 로고    scopus 로고
    • Emerging paradigms of T-cell co-stimulation
    • doi:10.1016/j.coi.2004.03.002
    • Kroczek RA, Mages HW, Hutloff A. Emerging paradigms of T-cell co-stimulation. Curr Opin Immunol (2004) 16(3):321-7. doi:10.1016/j.coi.2004.03.002
    • (2004) Curr Opin Immunol , vol.16 , Issue.3 , pp. 321-327
    • Kroczek, R.A.1    Mages, H.W.2    Hutloff, A.3
  • 115
    • 33746889097 scopus 로고    scopus 로고
    • Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
    • doi:10.1634/stemcells.2005-0008
    • Krampera M, Cosmi L, Angeli R, Pasini A, Liotta F, Andreini A, et al. Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells (2006) 24(2):386-98. doi:10.1634/stemcells.2005-0008
    • (2006) Stem Cells , vol.24 , Issue.2 , pp. 386-398
    • Krampera, M.1    Cosmi, L.2    Angeli, R.3    Pasini, A.4    Liotta, F.5    Andreini, A.6
  • 116
    • 0347600715 scopus 로고    scopus 로고
    • Immunomodulatory effects of fetal and adult mesenchymal stem cells
    • doi:10.1080/14653240310003611
    • Le Blanc K. Immunomodulatory effects of fetal and adult mesenchymal stem cells. Cytotherapy (2003) 5(6):485-9. doi:10.1080/14653240310003611
    • (2003) Cytotherapy , vol.5 , Issue.6 , pp. 485-489
    • Le Blanc, K.1
  • 117
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
    • doi:10.1016/S0301-472X(03)00110-3
    • Le Blanc K, Tammik C, Rosendahl K, Zetterberg E, Ringden O. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol (2003) 31(10):890-6. doi:10.1016/S0301-472X(03)00110-3
    • (2003) Exp Hematol , vol.31 , Issue.10 , pp. 890-896
    • Le Blanc, K.1    Tammik, C.2    Rosendahl, K.3    Zetterberg, E.4    Ringden, O.5
  • 118
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • doi:10.1182/blood-2004-04-1559
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood (2005) 105(4):1815-22. doi:10.1182/blood-2004-04-1559
    • (2005) Blood , vol.105 , Issue.4 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 119
    • 0036499224 scopus 로고    scopus 로고
    • Prostaglandins as modulators of immunity
    • doi:10.1016/S1471-4906(01)02154-8
    • Harris SG, Padilla J, Koumas L, Ray D, Phipps RP. Prostaglandins as modulators of immunity. Trends Immunol (2002) 23(3):144-50. doi:10.1016/S1471-4906(01)02154-8
    • (2002) Trends Immunol , vol.23 , Issue.3 , pp. 144-150
    • Harris, S.G.1    Padilla, J.2    Koumas, L.3    Ray, D.4    Phipps, R.P.5
  • 120
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2 3-dioxygenase-mediated tryptophan degradation
    • doi:10.1182/blood-2003-11-3909
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood (2004) 103(12):4619-21. doi:10.1182/blood-2003-11-3909
    • (2004) Blood , vol.103 , Issue.12 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 121
    • 84861574208 scopus 로고    scopus 로고
    • Hepatocyte growth factor mediates mesenchymal stem cell-induced recovery in multiple sclerosis models
    • doi:10.1038/nn.3109
    • Bai L, Lennon DP, Caplan AI, Dechant A, Hecker J, Kranso J, et al. Hepatocyte growth factor mediates mesenchymal stem cell-induced recovery in multiple sclerosis models. Nat Neurosci (2012) 15(6):862-70. doi:10.1038/nn.3109
    • (2012) Nat Neurosci , vol.15 , Issue.6 , pp. 862-870
    • Bai, L.1    Lennon, D.P.2    Caplan, A.I.3    Dechant, A.4    Hecker, J.5    Kranso, J.6
  • 122
    • 77950913921 scopus 로고    scopus 로고
    • Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25+Foxp3+ regulatory T cells
    • doi:10.1073/pnas.0912437107
    • Benkhoucha M, Santiago-Raber ML, Schneiter G, Chofflon M, Funakoshi H, Nakamura T, et al. Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25+Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A (2010) 107(14):6424-9. doi:10.1073/pnas.0912437107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.14 , pp. 6424-6429
    • Benkhoucha, M.1    Santiago-Raber, M.L.2    Schneiter, G.3    Chofflon, M.4    Funakoshi, H.5    Nakamura, T.6
  • 123
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • doi:10.1182/blood-2002-07-2104
    • Krampera M, Glennie S, Dyson J, Scott D, Laylor R, Simpson E, et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood (2003) 101(9):3722-9. doi:10.1182/blood-2002-07-2104
    • (2003) Blood , vol.101 , Issue.9 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6
  • 124
    • 1842483153 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
    • doi:10.1038/sj.bmt.1704400
    • Maitra B, Szekely E, Gjini K, Laughlin MJ, Dennis J, Haynesworth SE, et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant (2004) 33(6):597-604. doi:10.1038/sj.bmt.1704400
    • (2004) Bone Marrow Transplant , vol.33 , Issue.6 , pp. 597-604
    • Maitra, B.1    Szekely, E.2    Gjini, K.3    Laughlin, M.J.4    Dennis, J.5    Haynesworth, S.E.6
  • 125
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation
    • doi:10.1097/01.TP.0000045055.63901.A9
    • Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation (2003) 75(3):389-97. doi:10.1097/01.TP.0000045055.63901.A9
    • (2003) Transplantation , vol.75 , Issue.3 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 126
    • 0032759046 scopus 로고    scopus 로고
    • Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord
    • doi:10.1038/70986
    • McDonald JW, Liu XZ, Qu Y, Liu S, Mickey SK, Turetsky D, et al. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med (1999) 5(12):1410-2. doi:10.1038/70986
    • (1999) Nat Med , vol.5 , Issue.12 , pp. 1410-1412
    • McDonald, J.W.1    Liu, X.Z.2    Qu, Y.3    Liu, S.4    Mickey, S.K.5    Turetsky, D.6
  • 127
    • 24944499607 scopus 로고    scopus 로고
    • Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study
    • doi:10.1016/S0140-6736(05)67380-1
    • Menard C, Hagege AA, Agbulut O, Barro M, Morichetti MC, Brasselet C, et al. Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study. Lancet (2005) 366(9490):1005-12. doi:10.1016/S0140-6736(05)67380-1
    • (2005) Lancet , vol.366 , Issue.9490 , pp. 1005-1012
    • Menard, C.1    Hagege, A.A.2    Agbulut, O.3    Barro, M.4    Morichetti, M.C.5    Brasselet, C.6
  • 128
    • 77049118330 scopus 로고    scopus 로고
    • Xenogenic transplantation of human mesenchymal stem cells in a critical size defect of the sheep tibia for bone regeneration
    • doi:10.1089/ten.TEA.2009.0190
    • Niemeyer P, Schonberger TS, Hahn J, Kasten P, Fellenberg J, Suedkamp N, et al. Xenogenic transplantation of human mesenchymal stem cells in a critical size defect of the sheep tibia for bone regeneration. Tissue Eng Part A (2010) 16(1):33-43. doi:10.1089/ten.TEA.2009.0190
    • (2010) Tissue Eng Part A , vol.16 , Issue.1 , pp. 33-43
    • Niemeyer, P.1    Schonberger, T.S.2    Hahn, J.3    Kasten, P.4    Fellenberg, J.5    Suedkamp, N.6
  • 129
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
    • doi:10.1016/S0140-6736(08)60690-X
    • Le Blanc K, Frassoni F, Ball L, Locatelli F, Roelofs H, Lewis I, et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet (2008) 371(9624):1579-86. doi:10.1016/S0140-6736(08)60690-X
    • (2008) Lancet , vol.371 , Issue.9624 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3    Locatelli, F.4    Roelofs, H.5    Lewis, I.6
  • 130
    • 84856089950 scopus 로고    scopus 로고
    • Mesenchymal stem cells: application for solid-organ transplantation
    • doi:10.1097/MOT.0b013e32834ee676
    • Roemeling-van Rhijn M, Weimar W, Hoogduijn MJ. Mesenchymal stem cells: application for solid-organ transplantation. Curr Opin Organ Transplant (2012) 17(1):55-62. doi:10.1097/MOT.0b013e32834ee676
    • (2012) Curr Opin Organ Transplant , vol.17 , Issue.1 , pp. 55-62
    • Roemeling-van Rhijn, M.1    Weimar, W.2    Hoogduijn, M.J.3
  • 131
    • 20844434966 scopus 로고    scopus 로고
    • Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells
    • doi:10.4049/jimmunol.174.10.6477
    • Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, et al. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol (2005) 174(10):6477-89. doi:10.4049/jimmunol.174.10.6477
    • (2005) J Immunol , vol.174 , Issue.10 , pp. 6477-6489
    • Shultz, L.D.1    Lyons, B.L.2    Burzenski, L.M.3    Gott, B.4    Chen, X.5    Chaleff, S.6
  • 132
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • doi:10.1038/367645a0
    • Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature (1994) 367(6464):645-8. doi:10.1038/367645a0
    • (1994) Nature , vol.367 , Issue.6464 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3    Murdoch, B.4    Hoang, T.5    Caceres-Cortes, J.6
  • 134
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • doi:10.1038/nature03128
    • Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, et al. Identification of human brain tumour initiating cells. Nature (2004) 432(7015):396-401. doi:10.1038/nature03128
    • (2004) Nature , vol.432 , Issue.7015 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3    Squire, J.A.4    Bayani, J.5    Hide, T.6
  • 135
    • 34547113747 scopus 로고    scopus 로고
    • Tumor growth need not be driven by rare cancer stem cells
    • doi:10.1126/science.1142596
    • Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A. Tumor growth need not be driven by rare cancer stem cells. Science (2007) 317(5836):337. doi:10.1126/science.1142596
    • (2007) Science , vol.317 , Issue.5836 , pp. 337
    • Kelly, P.N.1    Dakic, A.2    Adams, J.M.3    Nutt, S.L.4    Strasser, A.5
  • 136
    • 33845267681 scopus 로고    scopus 로고
    • Characterization of stem cell-like cancer cells in immune-competent mice
    • doi:10.1182/blood-2006-05-024687
    • Kruger JA, Kaplan CD, Luo Y, Zhou H, Markowitz D, Xiang R, et al. Characterization of stem cell-like cancer cells in immune-competent mice. Blood (2006) 108(12):3906-12. doi:10.1182/blood-2006-05-024687
    • (2006) Blood , vol.108 , Issue.12 , pp. 3906-3912
    • Kruger, J.A.1    Kaplan, C.D.2    Luo, Y.3    Zhou, H.4    Markowitz, D.5    Xiang, R.6
  • 137
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: from immunosurveillance to tumor escape
    • doi:10.1038/ni1102-991
    • Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol (2002) 3(11):991-8. doi:10.1038/ni1102-991
    • (2002) Nat Immunol , vol.3 , Issue.11 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 138
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • doi:10.1038/nrc2256
    • Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer (2007) 7(11):834-46. doi:10.1038/nrc2256
    • (2007) Nat Rev Cancer , vol.7 , Issue.11 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 139
    • 28444486367 scopus 로고    scopus 로고
    • Stem cell niche: structure and function
    • doi:10.1146/annurev.cellbio.21.012704.131525
    • Li L, Xie T. Stem cell niche: structure and function. Annu Rev Cell Dev Biol (2005) 21:605-31. doi:10.1146/annurev.cellbio.21.012704.131525
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 605-631
    • Li, L.1    Xie, T.2
  • 140
    • 84894245627 scopus 로고    scopus 로고
    • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • doi:10.1038/nature13038
    • Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V, et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature (2014) 506(7488):328-33. doi:10.1038/nature13038
    • (2014) Nature , vol.506 , Issue.7488 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3    Chen, W.C.4    Brandwein, J.M.5    Gupta, V.6
  • 141
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • doi:10.1038/nature04186
    • Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature (2005) 438(7069):820-7. doi:10.1038/nature04186
    • (2005) Nature , vol.438 , Issue.7069 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3    Bramley, A.H.4    Vincent, L.5    Costa, C.6
  • 142
    • 84890314061 scopus 로고    scopus 로고
    • The pre-metastatic niche: finding common ground
    • doi:10.1007/s10555-013-9420-1
    • Sceneay J, Smyth MJ, Moller A. The pre-metastatic niche: finding common ground. Cancer Metastasis Rev (2013) 32(3-4):449-64. doi:10.1007/s10555-013-9420-1
    • (2013) Cancer Metastasis Rev , vol.32 , Issue.3-4 , pp. 449-464
    • Sceneay, J.1    Smyth, M.J.2    Moller, A.3
  • 143
    • 34547112565 scopus 로고    scopus 로고
    • WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism?
    • doi:10.1007/s00401-007-0231-8
    • Mehling M, Simon P, Mittelbronn M, Meyermann R, Ferrone S, Weller M, et al. WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism? Acta Neuropathol (2007) 114(2):111-9. doi:10.1007/s00401-007-0231-8
    • (2007) Acta Neuropathol , vol.114 , Issue.2 , pp. 111-119
    • Mehling, M.1    Simon, P.2    Mittelbronn, M.3    Meyermann, R.4    Ferrone, S.5    Weller, M.6
  • 144
    • 34249295619 scopus 로고    scopus 로고
    • Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands
    • doi:10.1038/nature05768
    • Kaiser BK, Yim D, Chow IT, Gonzalez S, Dai Z, Mann HH, et al. Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands. Nature (2007) 447(7143):482-6. doi:10.1038/nature05768
    • (2007) Nature , vol.447 , Issue.7143 , pp. 482-486
    • Kaiser, B.K.1    Yim, D.2    Chow, I.T.3    Gonzalez, S.4    Dai, Z.5    Mann, H.H.6
  • 145
    • 0015950349 scopus 로고
    • Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging
    • Gleason DF, Mellinger GT. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol (1974) 111(1):58-64.
    • (1974) J Urol , vol.111 , Issue.1 , pp. 58-64
    • Gleason, D.F.1    Mellinger, G.T.2
  • 146
    • 47149090942 scopus 로고    scopus 로고
    • Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects
    • doi:10.1097/MOH.0b013e328303b9df
    • Campbell C, Risueno RM, Salati S, Guezguez B, Bhatia M. Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects. Curr Opin Hematol (2008) 15(4):319-25. doi:10.1097/MOH.0b013e328303b9df
    • (2008) Curr Opin Hematol , vol.15 , Issue.4 , pp. 319-325
    • Campbell, C.1    Risueno, R.M.2    Salati, S.3    Guezguez, B.4    Bhatia, M.5
  • 147
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • doi:10.1038/nrclinonc.2010.196
    • Takebe N, Harris PJ, Warren RQ, Ivy SP. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol (2011) 8(2):97-106. doi:10.1038/nrclinonc.2010.196
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.2 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 148
    • 63649147784 scopus 로고    scopus 로고
    • Dysregulation of Hedgehog Wnt and Notch signalling pathways in breast cancer
    • Zardawi SJ, O'Toole SA, Sutherland RL, Musgrove EA. Dysregulation of Hedgehog, Wnt and Notch signalling pathways in breast cancer. Histol Histopathol (2009) 24(3):385-98.
    • (2009) Histol Histopathol , vol.24 , Issue.3 , pp. 385-398
    • Zardawi, S.J.1    O'Toole, S.A.2    Sutherland, R.L.3    Musgrove, E.A.4
  • 149
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • doi:10.1038/35077219
    • Taipale J, Beachy PA. The Hedgehog and Wnt signalling pathways in cancer. Nature (2001) 411(6835):349-54. doi:10.1038/35077219
    • (2001) Nature , vol.411 , Issue.6835 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 150
    • 84889598519 scopus 로고    scopus 로고
    • Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness
    • doi:10.1038/nature12830
    • Li Q, Bohin N, Wen T, Ng V, Magee J, Chen SC, et al. Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness. Nature (2013) 504(7478):143-7. doi:10.1038/nature12830
    • (2013) Nature , vol.504 , Issue.7478 , pp. 143-147
    • Li, Q.1    Bohin, N.2    Wen, T.3    Ng, V.4    Magee, J.5    Chen, S.C.6
  • 151
    • 84858796262 scopus 로고    scopus 로고
    • IDH mutation impairs histone demethylation and results in a block to cell differentiation
    • doi:10.1038/nature10860
    • Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature (2012) 483(7390):474-8. doi:10.1038/nature10860
    • (2012) Nature , vol.483 , Issue.7390 , pp. 474-478
    • Lu, C.1    Ward, P.S.2    Kapoor, G.S.3    Rohle, D.4    Turcan, S.5    Abdel-Wahab, O.6
  • 152
    • 0037315894 scopus 로고    scopus 로고
    • Disruption of differentiation in human cancer: AML shows the way
    • doi:10.1038/nrc989
    • Tenen DG. Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer (2003) 3(2):89-101. doi:10.1038/nrc989
    • (2003) Nat Rev Cancer , vol.3 , Issue.2 , pp. 89-101
    • Tenen, D.G.1
  • 153
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation
    • doi:10.1093/jnci/djj495
    • Phillips TM, McBride WH, Pajonk F. The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst (2006) 98(24):1777-85. doi:10.1093/jnci/djj495
    • (2006) J Natl Cancer Inst , vol.98 , Issue.24 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 154
    • 48649104080 scopus 로고    scopus 로고
    • Temozolomide preferentially depletes cancer stem cells in glioblastoma
    • doi:10.1158/0008-5472.CAN-07-6878
    • Beier D, Rohrl S, Pillai DR, Schwarz S, Kunz-Schughart LA, Leukel P, et al. Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res (2008) 68(14):5706-15. doi:10.1158/0008-5472.CAN-07-6878
    • (2008) Cancer Res , vol.68 , Issue.14 , pp. 5706-5715
    • Beier, D.1    Rohrl, S.2    Pillai, D.R.3    Schwarz, S.4    Kunz-Schughart, L.A.5    Leukel, P.6
  • 155
    • 84897431499 scopus 로고    scopus 로고
    • Targeting of pre-existing and induced breast cancer stem cells with trastuzumab and trastuzumab emtansine (T-DM1)
    • doi:10.1038/cddis.2014.115
    • Diessner J, Bruttel V, Stein R, Horn E, Häusler S, Dietl J, et al. Targeting of pre-existing and induced breast cancer stem cells with trastuzumab and trastuzumab emtansine (T-DM1). Cell Death Dis (2014) 5:e1149. doi:10.1038/cddis.2014.115
    • (2014) Cell Death Dis , vol.5
    • Diessner, J.1    Bruttel, V.2    Stein, R.3    Horn, E.4    Häusler, S.5    Dietl, J.6
  • 156
  • 157
    • 84874000632 scopus 로고    scopus 로고
    • Cancer stem cells niche: a target for novel cancer therapeutics
    • doi:10.1016/j.ctrv.2012.10.004
    • Yi SY, Hao YB, Nan KJ, Fan TL. Cancer stem cells niche: a target for novel cancer therapeutics. Cancer Treat Rev (2013) 39(3):290-6. doi:10.1016/j.ctrv.2012.10.004
    • (2013) Cancer Treat Rev , vol.39 , Issue.3 , pp. 290-296
    • Yi, S.Y.1    Hao, Y.B.2    Nan, K.J.3    Fan, T.L.4
  • 158
    • 79551555038 scopus 로고    scopus 로고
    • Cancer stem cell niche: the place to be
    • doi:10.1158/0008-5472.CAN-10-3220
    • Borovski T, De Sousa EMF, Vermeulen L, Medema JP. Cancer stem cell niche: the place to be. Cancer Res (2011) 71(3):634-9. doi:10.1158/0008-5472.CAN-10-3220
    • (2011) Cancer Res , vol.71 , Issue.3 , pp. 634-639
    • Borovski, T.1    De Sousa, E.M.F.2    Vermeulen, L.3    Medema, J.P.4
  • 159
    • 84855425160 scopus 로고    scopus 로고
    • Interactions between cancer stem cells and their niche govern metastatic colonization
    • doi:10.1038/nature10694
    • Malanchi I, Santamaria-Martinez A, Susanto E, Peng H, Lehr HA, Delaloye JF, et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature (2012) 481(7379):85-9. doi:10.1038/nature10694
    • (2012) Nature , vol.481 , Issue.7379 , pp. 85-89
    • Malanchi, I.1    Santamaria-Martinez, A.2    Susanto, E.3    Peng, H.4    Lehr, H.A.5    Delaloye, J.F.6
  • 160
    • 40449105940 scopus 로고    scopus 로고
    • Equilibrium between host and cancer caused by effector T cells killing tumor stroma
    • doi:10.1158/0008-5472.CAN-07-5324
    • Zhang B, Zhang Y, Bowerman NA, Schietinger A, Fu YX, Kranz DM, et al. Equilibrium between host and cancer caused by effector T cells killing tumor stroma. Cancer Res (2008) 68(5):1563-71. doi:10.1158/0008-5472.CAN-07-5324
    • (2008) Cancer Res , vol.68 , Issue.5 , pp. 1563-1571
    • Zhang, B.1    Zhang, Y.2    Bowerman, N.A.3    Schietinger, A.4    Fu, Y.X.5    Kranz, D.M.6
  • 161
    • 84872617136 scopus 로고    scopus 로고
    • The ultimate goal of curative anti-cancer therapies: inducing an adaptive anti-tumor immune response
    • doi:10.3389/fimmu.2011.00066
    • Fridman WH, Teillaud JL, Sautes-Fridman C, Pages F, Galon J, Zucman-Rossi J, et al. The ultimate goal of curative anti-cancer therapies: inducing an adaptive anti-tumor immune response. Front Immunol (2011) 2:66. doi:10.3389/fimmu.2011.00066
    • (2011) Front Immunol , vol.2 , pp. 66
    • Fridman, W.H.1    Teillaud, J.L.2    Sautes-Fridman, C.3    Pages, F.4    Galon, J.5    Zucman-Rossi, J.6
  • 162
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • doi:10.1038/nm1622
    • Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A, et al. Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13(9):1050-9. doi:10.1038/nm1622
    • (2007) Nat Med , vol.13 , Issue.9 , pp. 1050-1059
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3    Obeid, M.4    Ortiz, C.5    Criollo, A.6
  • 163
    • 37549032137 scopus 로고    scopus 로고
    • Immunological aspects of cancer chemotherapy
    • doi:10.1038/nri2216
    • Zitvogel L, Apetoh L, Ghiringhelli F, Kroemer G. Immunological aspects of cancer chemotherapy. Nat Rev Immunol (2008) 8(1):59-73. doi:10.1038/nri2216
    • (2008) Nat Rev Immunol , vol.8 , Issue.1 , pp. 59-73
    • Zitvogel, L.1    Apetoh, L.2    Ghiringhelli, F.3    Kroemer, G.4
  • 164
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • doi:10.1056/NEJMoa1003466
    • Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med (2010) 363(8):711-23. doi:10.1056/NEJMoa1003466
    • (2010) N Engl J Med , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3    Weber, R.W.4    Sosman, J.A.5    Haanen, J.B.6
  • 165
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • doi:10.1056/NEJMoa1200690
    • Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med (2012) 366(26):2443-54. doi:10.1056/NEJMoa1200690
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3    Gettinger, S.N.4    Smith, D.C.5    McDermott, D.F.6
  • 167
    • 84864662070 scopus 로고    scopus 로고
    • Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
    • doi:10.1038/nm.2883
    • Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med (2012) 18(8):1254-61. doi:10.1038/nm.2883
    • (2012) Nat Med , vol.18 , Issue.8 , pp. 1254-1261
    • Walter, S.1    Weinschenk, T.2    Stenzl, A.3    Zdrojowy, R.4    Pluzanska, A.5    Szczylik, C.6
  • 168
    • 42549138499 scopus 로고    scopus 로고
    • Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines
    • doi:10.1038/nrc2373
    • Melief CJ, van der Burg SH. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat Rev Cancer (2008) 8(5):351-60. doi:10.1038/nrc2373
    • (2008) Nat Rev Cancer , vol.8 , Issue.5 , pp. 351-360
    • Melief, C.J.1    van der Burg, S.H.2
  • 169
    • 84900395848 scopus 로고    scopus 로고
    • Intermittent metronomic drug schedule is essential for activating antitumor innate immunity and tumor xenograft regression
    • doi:10.1593/neo.131910
    • Chen CS, Doloff JC, Waxman DJ. Intermittent metronomic drug schedule is essential for activating antitumor innate immunity and tumor xenograft regression. Neoplasia (2014) 16(1):84-96. doi:10.1593/neo.131910
    • (2014) Neoplasia , vol.16 , Issue.1 , pp. 84-96
    • Chen, C.S.1    Doloff, J.C.2    Waxman, D.J.3
  • 170
    • 84860815596 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide treatment in metastasized breast cancer patients: immunological effects and clinical outcome
    • doi:10.1007/s00262-011-1106-3
    • Ge Y, Domschke C, Stoiber N, Schott S, Heil J, Rom J, et al. Metronomic cyclophosphamide treatment in metastasized breast cancer patients: immunological effects and clinical outcome. Cancer Immunol Immunother (2012) 61(3):353-62. doi:10.1007/s00262-011-1106-3
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.3 , pp. 353-362
    • Ge, Y.1    Domschke, C.2    Stoiber, N.3    Schott, S.4    Heil, J.5    Rom, J.6


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