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Volumn 5, Issue 7, 2014, Pages 559-571

Far beyond the usual biomarkers in breast cancer: A review

Author keywords

Biomarkers; Breast cancer; Chemotherapy resistance; Early diagnosis; Prognosis

Indexed keywords


EID: 84905491265     PISSN: None     EISSN: 18379664     Source Type: Journal    
DOI: 10.7150/jca.8925     Document Type: Review
Times cited : (47)

References (127)
  • 1
    • 38349038425 scopus 로고    scopus 로고
    • Westernizing women's risks? Breast cancer in lower-income countries
    • doi:10.1056/NEJMp0708307
    • Porter P. Westernizing women's risks? Breast cancer in lower-income countries. The New England journal of medicine. 2008; 358: 213-6. doi:10.1056/NEJMp0708307.
    • (2008) The New England journal of medicine , vol.358 , pp. 213-216
    • Porter, P.1
  • 4
    • 0035922670 scopus 로고    scopus 로고
    • Cochrane review on screening for breast cancer with mammography
    • doi:10. 1016/S0140-6736(01)
    • Olsen O, Gotzsche PC. Cochrane review on screening for breast cancer with mammography. Lancet. 2001; 358: 1340-2. doi:10.1016/S0140-6736(01)06449-2.
    • (2001) Lancet , vol.358 , pp. 1340-1342
    • Olsen, O.1    Gotzsche, P.C.2
  • 5
    • 33645031138 scopus 로고    scopus 로고
    • The knowledge and attitudes of breast self-examination and mammography in a group of women in a rural area in western Turkey
    • doi:10.1186/1471-2407-6-43
    • Dundar PE, Ozmen D, Ozturk B, Haspolat G, Akyildiz F, Coban S, et al. The knowledge and attitudes of breast self-examination and mammography in a group of women in a rural area in western Turkey. BMC cancer. 2006; 6: 43. doi:10.1186/1471-2407-6-43.
    • (2006) BMC cancer , vol.6 , pp. 43
    • Dundar, P.E.1    Ozmen, D.2    Ozturk, B.3    Haspolat, G.4    Akyildiz, F.5    Coban, S.6
  • 6
    • 12344251753 scopus 로고    scopus 로고
    • Digital mammography
    • doi:10.1148/radiol.2342030897
    • Pisano ED, Yaffe MJ. Digital mammography. Radiology. 2005; 234: 353-62. doi:10.1148/radiol.2342030897.
    • (2005) Radiology , vol.234 , pp. 353-362
    • Pisano, E.D.1    Yaffe, M.J.2
  • 7
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents, defining priorities to reduce cancer disparities in different geographic regions of the world, Journal of clinical oncology, official
    • doi:10.1200/JCO.2005.05.2308
    • Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2006; 24: 2137-50. doi:10.1200/JCO.2005.05.2308.
    • (2006) journal of the American Society of Clinical Oncology , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 8
    • 0023137823 scopus 로고
    • The clinical course of bone metastases from breast cancer
    • Coleman RE, Rubens RD. The clinical course of bone metastases from breast cancer. British journal of cancer. 1987; 55: 61-6.
    • (1987) British journal of cancer , vol.55 , pp. 61-66
    • Coleman, R.E.1    Rubens, R.D.2
  • 10
    • 37649007431 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators and antihormonal resistance in breast cancer, Journal of clinical oncology, official
    • doi:10.1200/JCO.2007.11.3886
    • Jordan VC, O'Malley BW. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2007; 25: 5815-24. doi:10.1200/JCO.2007.11.3886.
    • (2007) journal of the American Society of Clinical Oncology , vol.25 , pp. 5815-5824
    • Jordan, V.C.1    O'Malley, B.W.2
  • 11
    • 85201888298 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer, an overview of the randomised, trials., Early Breast Cancer Trialists'
    • Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. Lancet. 1998; 351: 1451-67.
    • (1998) Collaborative, Group., Lancet. , vol.351
  • 13
    • 77954700380 scopus 로고    scopus 로고
    • Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
    • doi:10.1200/JCO.2008.21.6457
    • Miles DW, Chan A, Dirix LY, Cortes J, Pivot X, Tomczak P, et al. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2010; 28: 3239-47. doi:10.1200/JCO.2008.21.6457.
    • (2010) Journal of clinical oncology, official journal of the American Society of Clinical Oncology , vol.28 , pp. 3239-3247
    • Miles, D.W.1    Chan, A.2    Dirix, L.Y.3    Cortes, J.4    Pivot, X.5    Tomczak, P.6
  • 14
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • doi:10.1056/NEJMoa072113
    • Miller K, Wang M, Gralow J, Dickler M, Cobleigh M, Perez EA, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. The New England journal of medicine. 2007; 357: 2666-76. doi:10.1056/NEJMoa072113.
    • (2007) The New England journal of medicine , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3    Dickler, M.4    Cobleigh, M.5    Perez, E.A.6
  • 15
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • doi:10.1002/path.1706
    • Longley DB, Johnston PG. Molecular mechanisms of drug resistance. The Journal of pathology. 2005; 205: 275-92. doi:10.1002/path.1706.
    • (2005) The Journal of pathology , vol.205 , pp. 275-292
    • Longley, D.B.1    Johnston, P.G.2
  • 16
    • 0036329424 scopus 로고    scopus 로고
    • Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer, from pilot to level 1 evidence studies
    • Duffy MJ. Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: from pilot to level 1 evidence studies. Clinical chemistry. 2002; 48: 1194-7.
    • (2002) Clinical chemistry , vol.48 , pp. 1194-1197
    • Duffy, M.J.1
  • 17
    • 0027082979 scopus 로고
    • Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer
    • Janicke F, Schmitt M, Pache L, Ulm K, Harbeck N, Hofler H, et al. Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer. Breast cancer research and treatment. 1993; 24: 195-208.
    • (1993) Breast cancer research and treatment , vol.24 , pp. 195-208
    • Janicke, F.1    Schmitt, M.2    Pache, L.3    Ulm, K.4    Harbeck, N.5    Hofler, H.6
  • 18
    • 0021141716 scopus 로고
    • T and Tn, general carcinoma autoantigens
    • Springer GF. T and Tn, general carcinoma autoantigens. Science. 1984; 224: 1198-206.
    • (1984) Science , vol.224 , pp. 1198-1206
    • Springer, G.F.1
  • 20
    • 77957198675 scopus 로고    scopus 로고
    • Carbohydrate antigens in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy
    • doi:10.1186/1471-2407-10-519
    • Deutscher SL, Dickerson M, Gui G, Newton J, Holm JE, Vogeltanz-Holm N, et al. Carbohydrate antigens in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy. BMC cancer. 2010; 10: 519. doi:10.1186/1471-2407-10-519.
    • (2010) BMC cancer , vol.10 , pp. 519
    • Deutscher, S.L.1    Dickerson, M.2    Gui, G.3    Newton, J.4    Holm, J.E.5    Vogeltanz-Holm, N.6
  • 21
    • 84856405871 scopus 로고    scopus 로고
    • Proteins and carbohydrates in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy
    • doi:10.1186/1471-2407-12-52
    • Qin W, Gui G, Zhang K, Twelves D, Kliethermes B, Sauter ER. Proteins and carbohydrates in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy. BMC cancer. 2012; 12: 52. doi:10.1186/1471-2407-12-52.
    • (2012) BMC cancer , vol.12 , pp. 52
    • Qin, W.1    Gui, G.2    Zhang, K.3    Twelves, D.4    Kliethermes, B.5    Sauter, E.R.6
  • 22
    • 0028074616 scopus 로고
    • Isolation of differentially expressed sequence tags from human breast cancer
    • Watson MA, Fleming TP. Isolation of differentially expressed sequence tags from human breast cancer. Cancer research. 1994; 54: 4598-602.
    • (1994) Cancer research , vol.54 , pp. 4598-4602
    • Watson, M.A.1    Fleming, T.P.2
  • 23
    • 0030056285 scopus 로고    scopus 로고
    • Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer
    • Watson MA, Fleming TP. Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer. Cancer research. 1996; 56: 860-5.
    • (1996) Cancer research , vol.56 , pp. 860-865
    • Watson, M.A.1    Fleming, T.P.2
  • 24
    • 80052901704 scopus 로고    scopus 로고
    • Cloning expression, monoclonal antibody preparation and serologic study of mammaglobin in breast cancer
    • Huang Y, Zhang HQ, Wang J, Song XG, Wang GH, Guan Q, et al. Cloning expression, monoclonal antibody preparation and serologic study of mammaglobin in breast cancer. Neoplasma. 2011; 58: 436-40.
    • (2011) Neoplasma , vol.58 , pp. 436-440
    • Huang, Y.1    Zhang, H.Q.2    Wang, J.3    Song, X.G.4    Wang, G.H.5    Guan, Q.6
  • 26
    • 84875525974 scopus 로고    scopus 로고
    • Plasma human mammaglobin mRNA associated with poor outcome in patients with breast cancer
    • doi:10.4238/2012.November.28.2
    • Lee GW, Kim JY, Koh EH, Kang D, Choi DS, Maeng KY, et al. Plasma human mammaglobin mRNA associated with poor outcome in patients with breast cancer. Genetics and molecular research: GMR. 2012; 11: 4034-42. doi:10.4238/2012.November.28.2.
    • (2012) Genetics and molecular research, GMR , vol.11 , pp. 4034-4042
    • Lee, G.W.1    Kim, J.Y.2    Koh, E.H.3    Kang, D.4    Choi, D.S.5    Maeng, K.Y.6
  • 27
    • 84862933571 scopus 로고    scopus 로고
    • Expression of human mammaglobin as a marker of bone marrow micrometastasis in breast cancer
    • doi:10.3892/etm.2011.429
    • Liu Y, Ma L, Liu X, Wang L. Expression of human mammaglobin as a marker of bone marrow micrometastasis in breast cancer. Experimental and therapeutic medicine. 2012; 3: 550-4. doi:10.3892/etm.2011.429.
    • (2012) Experimental and therapeutic medicine , vol.3 , pp. 550-554
    • Liu, Y.1    Ma, L.2    Liu, X.3    Wang, L.4
  • 28
    • 84879213605 scopus 로고    scopus 로고
    • Expression of mammaglobin and gross cystic disease fluid protein-15 in breast carcinomas
    • doi:10.1016/j.humpath.2012.10.009
    • Luo MH, Huang YH, Ni YB, Tsang JY, Chan SK, Shao MM, et al. Expression of mammaglobin and gross cystic disease fluid protein-15 in breast carcinomas. Human pathology. 2013; 44: 1241-50. doi:10.1016/j.humpath.2012.10.009.
    • (2013) Human pathology , vol.44 , pp. 1241-1250
    • Luo, M.H.1    Huang, Y.H.2    Ni, Y.B.3    Tsang, J.Y.4    Chan, S.K.5    Shao, M.M.6
  • 29
    • 84871116041 scopus 로고    scopus 로고
    • Gross cystic disease fluid protein-15 and mammaglobin A expression determined by immunohistochemistry is of limited utility in triple-negative breast cancer
    • doi:10.1111/j.1365-2559.2012.04344.x
    • Huo L, Zhang J, Gilcrease MZ, Gong Y, Wu Y, Zhang H, et al. Gross cystic disease fluid protein-15 and mammaglobin A expression determined by immunohistochemistry is of limited utility in triple-negative breast cancer. Histopathology. 2013; 62: 267-74. doi:10.1111/j.1365-2559.2012.04344.x.
    • (2013) Histopathology , vol.62 , pp. 267-274
    • Huo, L.1    Zhang, J.2    Gilcrease, M.Z.3    Gong, Y.4    Wu, Y.5    Zhang, H.6
  • 30
    • 1442307852 scopus 로고    scopus 로고
    • Mammaglobin is associated with low-grade, steroid receptor-positive breast tumors from postmenopausal patients, and has independent prognostic value for relapse-free survival time
    • doi:10.1200/JCO.2004.01.072
    • Span PN, Waanders E, Manders P, Heuvel JJ, Foekens JA, Watson MA, et al. Mammaglobin is associated with low-grade, steroid receptor-positive breast tumors from postmenopausal patients, and has independent prognostic value for relapse-free survival time. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2004; 22: 691-8. doi:10.1200/JCO.2004.01.072.
    • (2004) Journal of clinical oncology, official journal of the American Society of Clinical Oncology , vol.22 , pp. 691-698
    • Span, P.N.1    Waanders, E.2    Manders, P.3    Heuvel, J.J.4    Foekens, J.A.5    Watson, M.A.6
  • 31
    • 0018426687 scopus 로고
    • Transformed mammalian cells secrete specific proteins and phosphoproteins
    • Senger DR, Wirth DF, Hynes RO. Transformed mammalian cells secrete specific proteins and phosphoproteins. Cell. 1979; 16: 885-93.
    • (1979) Cell , vol.16 , pp. 885-893
    • Senger, D.R.1    Wirth, D.F.2    Hynes, R.O.3
  • 33
    • 78651376714 scopus 로고    scopus 로고
    • Categorical meta-analysis of Osteopontin as a clinical cancer marker
    • doi:10.3892/or.2010.1106
    • Weber GF, Lett GS, Haubein NC. Categorical meta-analysis of Osteopontin as a clinical cancer marker. Oncology reports. 2011; 25: 433-41. doi:10.3892/or.2010.1106.
    • (2011) Oncology reports , vol.25 , pp. 433-441
    • Weber, G.F.1    Lett, G.S.2    Haubein, N.C.3
  • 34
    • 84886800484 scopus 로고    scopus 로고
    • Association of osteopontin and cyclooxygenase-2 expression with breast cancer subtypes and their use as potential biomarkers
    • doi:10.3892/ol.2013.1600
    • Thorat D, Sahu A, Behera R, Lohite K, Deshmukh S, Mane A, et al. Association of osteopontin and cyclooxygenase-2 expression with breast cancer subtypes and their use as potential biomarkers. Oncology letters. 2013; 6: 1559-64. doi:10.3892/ol.2013.1600.
    • (2013) Oncology letters , vol.6 , pp. 1559-1564
    • Thorat, D.1    Sahu, A.2    Behera, R.3    Lohite, K.4    Deshmukh, S.5    Mane, A.6
  • 35
    • 77956442992 scopus 로고    scopus 로고
    • Osteopontin is a marker for cancer aggressiveness and patient survival
    • doi:10.1038/sj.bjc.6605834
    • Weber GF, Lett GS, Haubein NC. Osteopontin is a marker for cancer aggressiveness and patient survival. British journal of cancer. 2010; 103: 861-9. doi:10.1038/sj.bjc.6605834.
    • (2010) British journal of cancer , vol.103 , pp. 861-869
    • Weber, G.F.1    Lett, G.S.2    Haubein, N.C.3
  • 36
    • 79953727008 scopus 로고    scopus 로고
    • Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis
    • doi:10.1093/carcin/bgr009
    • Mi Z, Bhattacharya SD, Kim VM, Guo H, Talbot LJ, Kuo PC. Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis. Carcinogenesis. 2011; 32: 477-87. doi:10.1093/carcin/bgr009.
    • (2011) Carcinogenesis , vol.32 , pp. 477-487
    • Mi, Z.1    Bhattacharya, S.D.2    Kim, V.M.3    Guo, H.4    Talbot, L.J.5    Kuo, P.C.6
  • 37
    • 33645743036 scopus 로고    scopus 로고
    • An osteopontin splice variant induces anchorage independence in human breast cancer cells
    • doi:10.1038/sj.onc.1209248
    • He B, Mirza M, Weber GF. An osteopontin splice variant induces anchorage independence in human breast cancer cells. Oncogene. 2006; 25: 2192-202. doi:10.1038/sj.onc.1209248.
    • (2006) Oncogene , vol.25 , pp. 2192-2202
    • He, B.1    Mirza, M.2    Weber, G.F.3
  • 39
    • 84888301068 scopus 로고    scopus 로고
    • Prognostic values of osteopontin-c E-cadherin and beta-catenin in breast cancer.
    • doi:10.1016/j.canep.2013.08.005
    • Pang H, Lu H, Song H, Meng Q, Zhao Y, Liu N, et al. Prognostic values of osteopontin-c, E-cadherin and beta-catenin in breast cancer. Cancer epidemiology. 2013. doi:10.1016/j.canep.2013.08.005.
    • (2013) Cancer epidemiology.
    • Pang, H.1    Lu, H.2    Song, H.3    Meng, Q.4    Zhao, Y.5    Liu, N.6
  • 40
    • 84894071187 scopus 로고    scopus 로고
    • Association of increased osteopontin and splice variant-c mRNA expression with HER2 and triple-negative/basal-like breast carcinomas subtypes and recurrence
    • doi:10.1016/j.humpath.2013.10.015
    • Ortiz-Martinez F, Perez-Balaguer A, Ciprian D, Andres L, Ponce J, Adrover E, et al. Association of increased osteopontin and splice variant-c mRNA expression with HER2 and triple-negative/basal-like breast carcinomas subtypes and recurrence. Human pathology. 2013. doi:10.1016/j.humpath.2013.10.015.
    • (2013) Human pathology
    • Ortiz-Martinez, F.1    Perez-Balaguer, A.2    Ciprian, D.3    Andres, L.4    Ponce, J.5    Adrover, E.6
  • 41
    • 84879554043 scopus 로고    scopus 로고
    • Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype
    • doi:10.1016/j.jamcollsurg.2013.02.025
    • Li NY, Weber CE, Mi Z, Wai PY, Cuevas BD, Kuo PC. Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype. Journal of the American College of Surgeons. 2013; 217: 17-26; discussion doi:10.1016/j.jamcollsurg.2013.02.025.
    • (2013) Journal of the American College of Surgeons , vol.217 , pp. 17-26
    • Li, N.Y.1    Weber, C.E.2    Mi, Z.3    Wai, P.Y.4    Cuevas, B.D.5    Kuo, P.C.6
  • 43
    • 84864401436 scopus 로고    scopus 로고
    • Fibroblast growth factor receptors in breast cancer, expression, downstream effects, and possible drug targets
    • doi:10.1530/ERC-12-0060
    • Tenhagen M, van Diest PJ, Ivanova IA, van der Wall E, van der Groep P. Fibroblast growth factor receptors in breast cancer: expression, downstream effects, and possible drug targets. Endocr Relat Cancer. 2012; 19: R115-29. doi:10.1530/ERC-12-0060.
    • (2012) Endocr Relat Cancer , vol.19
    • Tenhagen, M.1    van Diest, P.J.2    Ivanova, I.A.3    van der Wall, E.4    van der Groep, P.5
  • 44
    • 34250001297 scopus 로고    scopus 로고
    • A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
    • doi:10.1038/ng2075
    • Hunter DJ, Kraft P, Jacobs KB, Cox DG, Yeager M, Hankinson SE, et al. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet. 2007; 39: 870-4. doi:10.1038/ng2075.
    • (2007) Nat Genet , vol.39 , pp. 870-874
    • Hunter, D.J.1    Kraft, P.2    Jacobs, K.B.3    Cox, D.G.4    Yeager, M.5    Hankinson, S.E.6
  • 45
    • 34250006413 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel breast cancer susceptibility loci
    • doi:10.1038/nature05887
    • Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature. 2007; 447: 1087-93. doi:10.1038/nature05887.
    • (2007) Nature , vol.447 , pp. 1087-1093
    • Easton, D.F.1    Pooley, K.A.2    Dunning, A.M.3    Pharoah, P.D.4    Thompson, D.5    Ballinger, D.G.6
  • 46
    • 84871803181 scopus 로고    scopus 로고
    • FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells
    • doi:10.1371/journal.pone.0051671
    • Kim S, Dubrovska A, Salamone RJ, Walker JR, Grandinetti KB, Bonamy GM, et al. FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells. PloS one. 2013; 8: e51671. doi:10.1371/journal.pone.0051671.
    • (2013) PloS one , vol.8
    • Kim, S.1    Dubrovska, A.2    Salamone, R.J.3    Walker, J.R.4    Grandinetti, K.B.5    Bonamy, G.M.6
  • 47
    • 69449083319 scopus 로고    scopus 로고
    • Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer
    • doi:10.1210/me.2009-0071
    • Zhu X, Asa SL, Ezzat S. Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer. Mol Endocrinol. 2009; 23: 1397-405. doi:10.1210/me.2009-0071.
    • (2009) Mol Endocrinol , vol.23 , pp. 1397-1405
    • Zhu, X.1    Asa, S.L.2    Ezzat, S.3
  • 48
    • 9344222224 scopus 로고    scopus 로고
    • Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells
    • Moffa AB, Tannheimer SL, Ethier SP. Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells. Mol Cancer Res. 2004; 2: 643-52.
    • (2004) Mol Cancer Res , vol.2 , pp. 643-652
    • Moffa, A.B.1    Tannheimer, S.L.2    Ethier, S.P.3
  • 49
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23 3 that is mutated in multiple advanced cancers.
    • doi:10.1038/ng0497-356
    • Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet. 1997; 15: 356-62. doi:10.1038/ng0497-356.
    • (1997) Nat Genet. , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3    Yung, W.K.4    Lin, H.5    Ligon, A.H.6
  • 50
    • 33846557325 scopus 로고    scopus 로고
    • Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma
    • doi:10.1007/s10549-006-9295-8
    • Tokunaga E, Oki E, Kimura Y, Yamanaka T, Egashira A, Nishida K, et al. Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma. Breast Cancer Res Treat. 2007; 101: 249-57. doi:10.1007/s10549-006-9295-8.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 249-257
    • Tokunaga, E.1    Oki, E.2    Kimura, Y.3    Yamanaka, T.4    Egashira, A.5    Nishida, K.6
  • 51
    • 33947125457 scopus 로고    scopus 로고
    • Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers
    • doi:10.1016/j.bbrc.2007.02.136
    • Nakajima H, Sakaguchi K, Fujiwara I, Mizuta M, Tsuruga M, Magae J, et al. Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers. Biochem Biophys Res Commun. 2007; 356: 260-5. doi:10.1016/j.bbrc.2007.02.136.
    • (2007) Biochem Biophys Res Commun , vol.356 , pp. 260-265
    • Nakajima, H.1    Sakaguchi, K.2    Fujiwara, I.3    Mizuta, M.4    Tsuruga, M.5    Magae, J.6
  • 52
    • 79954515439 scopus 로고    scopus 로고
    • PTEN protein expression in postmenopausal steroid receptor positive early breast cancer patients treated with adjuvant tamoxifen
    • Milovanovic Z, Dzodic R, Susnjar S, Plesinac-Karapandzic V, Juranic Z, Tatic S. PTEN protein expression in postmenopausal steroid receptor positive early breast cancer patients treated with adjuvant tamoxifen. J BUON. 2011; 16: 46-51.
    • (2011) J BUON , vol.16 , pp. 46-51
    • Milovanovic, Z.1    Dzodic, R.2    Susnjar, S.3    Plesinac-Karapandzic, V.4    Juranic, Z.5    Tatic, S.6
  • 53
    • 84878283510 scopus 로고    scopus 로고
    • PTEN mutation, methylation and expression in breast cancer patients
    • doi:10.3892/ol.2013.1331
    • Zhang HY, Liang F, Jia ZL, Song ST, Jiang ZF. PTEN mutation, methylation and expression in breast cancer patients. Oncol Lett. 2013; 6: 161-8. doi:10.3892/ol.2013.1331.
    • (2013) Oncol Lett , vol.6 , pp. 161-168
    • Zhang, H.Y.1    Liang, F.2    Jia, Z.L.3    Song, S.T.4    Jiang, Z.F.5
  • 54
    • 33750212896 scopus 로고    scopus 로고
    • Altered sirtuin expression is associated with node-positive breast cancer
    • doi:10.1038/sj.bjc.6603384
    • Ashraf N, Zino S, Macintyre A, Kingsmore D, Payne AP, George WD, et al. Altered sirtuin expression is associated with node-positive breast cancer. British journal of cancer. 2006; 95: 1056-61. doi:10.1038/sj.bjc.6603384.
    • (2006) British journal of cancer , vol.95 , pp. 1056-1061
    • Ashraf, N.1    Zino, S.2    Macintyre, A.3    Kingsmore, D.4    Payne, A.P.5    George, W.D.6
  • 55
    • 78649328799 scopus 로고    scopus 로고
    • Sirtuin regulation of mitochondria, energy production, apoptosis, and signaling
    • doi:10.1016/j.tibs.2010.07.003
    • Verdin E, Hirschey MD, Finley LW, Haigis MC. Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends in biochemical sciences. 2010; 35: 669-75. doi:10.1016/j.tibs.2010.07.003.
    • (2010) Trends in biochemical sciences , vol.35 , pp. 669-675
    • Verdin, E.1    Hirschey, M.D.2    Finley, L.W.3    Haigis, M.C.4
  • 56
    • 79952501323 scopus 로고    scopus 로고
    • SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
    • doi:10.1016/j.ccr.2011.02.014
    • Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization. Cancer cell. 2011; 19: 416-28. doi:10.1016/j.ccr.2011.02.014.
    • (2011) Cancer cell , vol.19 , pp. 416-428
    • Finley, L.W.1    Carracedo, A.2    Lee, J.3    Souza, A.4    Egia, A.5    Zhang, J.6
  • 57
    • 74049094817 scopus 로고    scopus 로고
    • SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
    • doi:10.1016/j.ccr.2009.11.023
    • Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, et al. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer cell. 2010; 17: 41-52. doi:10.1016/j.ccr.2009.11.023.
    • (2010) Cancer cell , vol.17 , pp. 41-52
    • Kim, H.S.1    Patel, K.2    Muldoon-Jacobs, K.3    Bisht, K.S.4    Aykin-Burns, N.5    Pennington, J.D.6
  • 58
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance, an emerging axis of evil in the war on cancer
    • doi:10.1038/onc.2010.215
    • Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene. 2010; 29: 4741-51. doi:10.1038/onc.2010.215.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 59
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • doi:10.1038/35102167
    • Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414: 105-11. doi:10.1038/35102167.
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 60
    • 33845809125 scopus 로고    scopus 로고
    • Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis, role of fibroblast growth factor receptor-2
    • doi:10.1158/0008-5472.CAN-06-2044
    • Chaffer CL, Brennan JP, Slavin JL, Blick T, Thompson EW, Williams ED. Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2. Cancer Res. 2006; 66: 11271-8. doi:10.1158/0008-5472.CAN-06-2044.
    • (2006) Cancer Res , vol.66 , pp. 11271-11278
    • Chaffer, C.L.1    Brennan, J.P.2    Slavin, J.L.3    Blick, T.4    Thompson, E.W.5    Williams, E.D.6
  • 61
    • 84866337487 scopus 로고    scopus 로고
    • The bed and the bugs, interactions between the tumor microenvironment and cancer stem cells
    • doi:10.1016/j.semcancer.2012.04.006
    • Castano Z, Fillmore CM, Kim CF, McAllister SS. The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells. Semin Cancer Biol. 2012; 22: 462-70. doi:10.1016/j.semcancer.2012.04.006.
    • (2012) Semin Cancer Biol , vol.22 , pp. 462-470
    • Castano, Z.1    Fillmore, C.M.2    Kim, C.F.3    McAllister, S.S.4
  • 62
    • 58749108476 scopus 로고    scopus 로고
    • A novel mouse model of human breast cancer stem-like cells with high CD44+CD24-/lower phenotype metastasis to human bone
    • Ling LJ, Wang S, Liu XA, Shen EC, Ding Q, Lu C, et al. A novel mouse model of human breast cancer stem-like cells with high CD44+CD24-/lower phenotype metastasis to human bone. Chin Med J (Engl). 2008; 121: 1980-6.
    • (2008) Chin Med J (Engl) , vol.121 , pp. 1980-1986
    • Ling, L.J.1    Wang, S.2    Liu, X.A.3    Shen, E.C.4    Ding, Q.5    Lu, C.6
  • 63
    • 85047698213 scopus 로고    scopus 로고
    • Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
    • Blanco MJ, Moreno-Bueno G, Sarrio D, Locascio A, Cano A, Palacios J, et al. Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene. 2002; 21: 3241-6. doi:10.1038/sj.onc.1205416.
    • (2002) Oncogene , vol.21 , pp. 3241-3246
    • Blanco, M.J.1    Moreno-Bueno, G.2    Sarrio, D.3    Locascio, A.4    Cano, A.5    Palacios, J.6
  • 64
    • 84055216937 scopus 로고    scopus 로고
    • Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence
    • doi:10.1158/1541-7786.MCR-11-0371
    • Tran DD, Corsa CA, Biswas H, Aft RL, Longmore GD. Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Mol Cancer Res. 2011; 9: 1644-57. doi:10.1158/1541-7786.MCR-11-0371.
    • (2011) Mol Cancer Res , vol.9 , pp. 1644-1657
    • Tran, D.D.1    Corsa, C.A.2    Biswas, H.3    Aft, R.L.4    Longmore, G.D.5
  • 65
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • doi:10.1016/j.cell.2013.06.005
    • Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F, et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell. 2013; 154: 61-74. doi:10.1016/j.cell.2013.06.005.
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1    Marjanovic, N.D.2    Lee, T.3    Bell, G.4    Kleer, C.G.5    Reinhardt, F.6
  • 66
    • 19344364880 scopus 로고    scopus 로고
    • EarlyBreast Cancer Trialists' Collaborative G. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival, an overview of the randomised trials
    • doi:10. 1016/S0140-6736(05)
    • Early Breast Cancer Trialists' Collaborative G. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005; 365: 1687-717. doi:10.1016/S0140-6736(05)66544-0.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 67
    • 4243063941 scopus 로고    scopus 로고
    • Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro, prominent roles for CYP3A and CYP2D6
    • doi:10.1124/jpet.104.065607
    • Desta Z, Ward BA, Soukhova NV, Flockhart DA. Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. The Journal of pharmacology and experimental therapeutics. 2004; 310: 1062-75. doi:10.1124/jpet.104.065607.
    • (2004) The Journal of pharmacology and experimental therapeutics , vol.310 , pp. 1062-1075
    • Desta, Z.1    Ward, B.A.2    Soukhova, N.V.3    Flockhart, D.A.4
  • 68
    • 3342932419 scopus 로고    scopus 로고
    • Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen
    • doi:10.1023/B:BREA.0000025406.31193.e8
    • Johnson MD, Zuo H, Lee KH, Trebley JP, Rae JM, Weatherman RV, et al. Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen. Breast cancer research and treatment. 2004; 85: 151-9. doi:10.1023/B:BREA.0000025406.31193.e8.
    • (2004) Breast cancer research and treatment , vol.85 , pp. 151-159
    • Johnson, M.D.1    Zuo, H.2    Lee, K.H.3    Trebley, J.P.4    Rae, J.M.5    Weatherman, R.V.6
  • 70
    • 33645116164 scopus 로고    scopus 로고
    • Cytochrome P450 pharmacogenetics and cancer
    • doi:10.1038/sj.onc.1209377
    • Rodriguez-Antona C, Ingelman-Sundberg M. Cytochrome P450 pharmacogenetics and cancer. Oncogene. 2006; 25: 1679-91. doi:10.1038/sj.onc.1209377.
    • (2006) Oncogene , vol.25 , pp. 1679-1691
    • Rodriguez-Antona, C.1    Ingelman-Sundberg, M.2
  • 71
    • 79953848236 scopus 로고    scopus 로고
    • Impact of CYP2D6, CYP3A5CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients.
    • doi:10.1111/j.1365-2125.2011.03905.x
    • Lim JS, Chen XA, Singh O, Yap YS, Ng RC, Wong NS, et al. Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients. British journal of clinical pharmacology. 2011; 71: 737-50. doi:10.1111/j.1365-2125.2011.03905.x.
    • (2011) British journal of clinical pharmacology , vol.71 , pp. 737-750
    • Lim, J.S.1    Chen, X.A.2    Singh, O.3    Yap, Y.S.4    Ng, R.C.5    Wong, N.S.6
  • 73
    • 84859093970 scopus 로고    scopus 로고
    • CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer, the breast international group 1-98 trial
    • doi:10.1093/jnci/djs125
    • Regan MM, Leyland-Jones B, Bouzyk M, Pagani O, Tang W, Kammler R, et al. CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial. Journal of the National Cancer Institute. 2012; 104: 441-51. doi:10.1093/jnci/djs125.
    • (2012) Journal of the National Cancer Institute , vol.104 , pp. 441-451
    • Regan, M.M.1    Leyland-Jones, B.2    Bouzyk, M.3    Pagani, O.4    Tang, W.5    Kammler, R.6
  • 75
    • 84875520648 scopus 로고    scopus 로고
    • Analysis of circulating tumor DNA to monitor metastatic breast cancer
    • doi:10.1056/NEJMoa1213261
    • Dawson SJ, Tsui DW, Murtaza M, Biggs H, Rueda OM, Chin SF, et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med. 2013; 368: 1199-209. doi:10.1056/NEJMoa1213261.
    • (2013) N Engl J Med , vol.368 , pp. 1199-1209
    • Dawson, S.J.1    Tsui, D.W.2    Murtaza, M.3    Biggs, H.4    Rueda, O.M.5    Chin, S.F.6
  • 76
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • doi:10.1038/nature11412
    • Cancer Genome Atlas N. Comprehensive molecular portraits of human breast tumours. Nature. 2012; 490: 61-70. doi:10.1038/nature11412.
    • (2012) Nature , vol.490 , pp. 61-70
    • Cancer Genome Atlas, N.1
  • 77
    • 84884712906 scopus 로고    scopus 로고
    • Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer
    • doi:10.1016/j.breast.2013.08.001
    • Fu X, Osborne CK, SchiffR. Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer. Breast. 2013. doi:10.1016/j.breast.2013.08.001.
    • (2013) Breast
    • Fu, X.1    Osborne, C.K.2    Schiff, R.3
  • 78
    • 84883396637 scopus 로고    scopus 로고
    • Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies
    • doi:10.1073/pnas.1303204110
    • Hanker AB, Pfefferle AD, Balko JM, Kuba MG, Young CD, Sanchez V, et al. Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies. Proc Natl Acad Sci U S A. 2013; 110: 14372-7. doi:10.1073/pnas.1303204110.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 14372-14377
    • Hanker, A.B.1    Pfefferle, A.D.2    Balko, J.M.3    Kuba, M.G.4    Young, C.D.5    Sanchez, V.6
  • 79
    • 84878532044 scopus 로고    scopus 로고
    • Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab
    • doi:10.1038/bjc.2013.164
    • Cizkova M, Dujaric ME, Lehmann-Che J, Scott V, Tembo O, Asselain B, et al. Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab. British journal of cancer. 2013; 108: 1807-9. doi:10.1038/bjc.2013.164.
    • (2013) British journal of cancer , vol.108 , pp. 1807-1809
    • Cizkova, M.1    Dujaric, M.E.2    Lehmann-Che, J.3    Scott, V.4    Tembo, O.5    Asselain, B.6
  • 80
    • 84877582951 scopus 로고    scopus 로고
    • Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen
    • doi:10.1007/s10549-013-2529-7
    • Ramirez-Ardila DE, Helmijr JC, Look MP, Lurkin I, Ruigrok-Ritstier K, van Laere S, et al. Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen. Breast cancer research and treatment. 2013; 139: 39-49. doi:10.1007/s10549-013-2529-7.
    • (2013) Breast cancer research and treatment , vol.139 , pp. 39-49
    • Ramirez-Ardila, D.E.1    Helmijr, J.C.2    Look, M.P.3    Lurkin, I.4    Ruigrok-Ritstier, K.5    van Laere, S.6
  • 82
    • 0029157380 scopus 로고
    • Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells
    • Teixeira C, Reed JC, Pratt MA. Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells. Cancer research. 1995; 55: 3902-7.
    • (1995) Cancer research , vol.55 , pp. 3902-3907
    • Teixeira, C.1    Reed, J.C.2    Pratt, M.A.3
  • 83
    • 45549091674 scopus 로고    scopus 로고
    • Retinoic acid in development, towards an integrated view
    • doi:10.1038/nrg2340
    • Niederreither K, Dolle P. Retinoic acid in development: towards an integrated view. Nature reviews Genetics. 2008; 9: 541-53. doi:10.1038/nrg2340.
    • (2008) Nature reviews Genetics , vol.9 , pp. 541-553
    • Niederreither, K.1    Dolle, P.2
  • 84
    • 0032479430 scopus 로고    scopus 로고
    • Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells
    • Liu R, Takayama S, Zheng Y, Froesch B, Chen GQ, Zhang X, et al. Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells. The Journal of biological chemistry. 1998; 273: 16985-92.
    • (1998) The Journal of biological chemistry , vol.273 , pp. 16985-16992
    • Liu, R.1    Takayama, S.2    Zheng, Y.3    Froesch, B.4    Chen, G.Q.5    Zhang, X.6
  • 85
    • 67549104319 scopus 로고    scopus 로고
    • Genomic antagonism between retinoic acid and estrogen signaling in breast cancer
    • doi:10.1016/j.cell.2009.04.043
    • Hua S, Kittler R, White KP. Genomic antagonism between retinoic acid and estrogen signaling in breast cancer. Cell. 2009; 137: 1259-71. doi:10.1016/j.cell.2009.04.043.
    • (2009) Cell , vol.137 , pp. 1259-1271
    • Hua, S.1    Kittler, R.2    White, K.P.3
  • 86
    • 84880828042 scopus 로고    scopus 로고
    • Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer
    • doi:10.1038/ncomms3175
    • Johansson HJ, Sanchez BC, Mundt F, Forshed J, Kovacs A, Panizza E, et al. Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer. Nature communications. 2013; 4: 2175. doi:10.1038/ncomms3175.
    • (2013) Nature communications , vol.4 , pp. 2175
    • Johansson, H.J.1    Sanchez, B.C.2    Mundt, F.3    Forshed, J.4    Kovacs, A.5    Panizza, E.6
  • 87
    • 0028303977 scopus 로고
    • Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
    • Akira S, Nishio Y, Inoue M, Wang XJ, Wei S, Matsusaka T, et al. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell. 1994; 77: 63-71.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1    Nishio, Y.2    Inoue, M.3    Wang, X.J.4    Wei, S.5    Matsusaka, T.6
  • 88
    • 84868693885 scopus 로고    scopus 로고
    • Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
    • doi:10.1016/j.bbcan.2012.10.002
    • Subramaniam A, Shanmugam MK, Perumal E, Li F, Nachiyappan A, Dai X, et al. Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma. Biochim Biophys Acta. 2013; 1835: 46-60. doi:10.1016/j.bbcan.2012.10.002.
    • (2013) Biochim Biophys Acta , vol.1835 , pp. 46-60
    • Subramaniam, A.1    Shanmugam, M.K.2    Perumal, E.3    Li, F.4    Nachiyappan, A.5    Dai, X.6
  • 89
    • 84870873242 scopus 로고    scopus 로고
    • STAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro
    • doi:10.7555/JBR.26.20110050
    • Wang X, Wang G, Zhao Y, Liu X, Ding Q, Shi J, et al. STAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro. J Biomed Res. 2012; 26: 325-35. doi:10.7555/JBR.26.20110050.
    • (2012) J Biomed Res , vol.26 , pp. 325-335
    • Wang, X.1    Wang, G.2    Zhao, Y.3    Liu, X.4    Ding, Q.5    Shi, J.6
  • 90
    • 84873033728 scopus 로고    scopus 로고
    • STAT3-RANTES autocrine signaling is essential for tamoxifen resistance in human breast cancer cells
    • doi:10.1158/1541-7786.MCR-12-0217
    • Yi EH, Lee CS, Lee JK, Lee YJ, Shin MK, Cho CH, et al. STAT3-RANTES autocrine signaling is essential for tamoxifen resistance in human breast cancer cells. Mol Cancer Res. 2013; 11: 31-42. doi:10.1158/1541-7786.MCR-12-0217.
    • (2013) Mol Cancer Res , vol.11 , pp. 31-42
    • Yi, E.H.1    Lee, C.S.2    Lee, J.K.3    Lee, Y.J.4    Shin, M.K.5    Cho, C.H.6
  • 91
    • 31544460437 scopus 로고    scopus 로고
    • Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression
    • doi:10.1158/1078-0432.CCR-04-1749
    • Diaz N, Minton S, Cox C, Bowman T, Gritsko T, Garcia R, et al. Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression. Clin Cancer Res. 2006; 12: 20-8. doi:10.1158/1078-0432.CCR-04-1749.
    • (2006) Clin Cancer Res , vol.12 , pp. 20-28
    • Diaz, N.1    Minton, S.2    Cox, C.3    Bowman, T.4    Gritsko, T.5    Garcia, R.6
  • 92
    • 0037316938 scopus 로고    scopus 로고
    • Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis
    • Dolled-Filhart M, Camp RL, Kowalski DP, Smith BL, Rimm DL. Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis. Clin Cancer Res. 2003; 9: 594-600.
    • (2003) Clin Cancer Res , vol.9 , pp. 594-600
    • Dolled-Filhart, M.1    Camp, R.L.2    Kowalski, D.P.3    Smith, B.L.4    Rimm, D.L.5
  • 93
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • doi:10.1038/nrc745
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nature reviews Cancer. 2002; 2: 161-74. doi:10.1038/nrc745.
    • (2002) Nature reviews Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 94
    • 48849107531 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases in cell signaling, metalloproteinase-independent biological activities
    • doi:10.1126/scisignal.127re6
    • Stetler-Stevenson WG. Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities. Science signaling. 2008; 1: re6. doi:10.1126/scisignal.127re6.
    • (2008) Science signaling , vol.1
    • Stetler-Stevenson, W.G.1
  • 96
    • 84880299568 scopus 로고    scopus 로고
    • High expression of TIMP-1 in human breast cancer tissues is a predictive of resistance to paclitaxel-based chemotherapy
    • doi:10.1007/s12032-012-0239-3
    • Zhu D, Zha X, Hu M, Tao A, Zhou H, Zhou X, et al. High expression of TIMP-1 in human breast cancer tissues is a predictive of resistance to paclitaxel-based chemotherapy. Medical oncology. 2012; 29: 3207-15. doi:10.1007/s12032-012-0239-3.
    • (2012) Medical oncology , vol.29 , pp. 3207-3215
    • Zhu, D.1    Zha, X.2    Hu, M.3    Tao, A.4    Zhou, H.5    Zhou, X.6
  • 97
    • 79959673027 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 decreased chemosensitivity of MDA-435 breast cancer cells to chemotherapeutic drugs through the PI3K/AKT/NF-small ka CyrillicB pathway.
    • doi:10.1016/j.biopha.2011.02.004
    • Fu ZY, Lv JH, Ma CY, Yang DP, Wang T. Tissue inhibitor of metalloproteinase-1 decreased chemosensitivity of MDA-435 breast cancer cells to chemotherapeutic drugs through the PI3K/AKT/NF-small ka, CyrillicB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2011; 65: 163-7. doi:10.1016/j.biopha.2011.02.004.
    • (2011) Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. , vol.65 , pp. 163-167
    • Fu, Z.Y.1    Lv, J.H.2    Ma, C.Y.3    Yang, D.P.4    Wang, T.5
  • 98
    • 84883774480 scopus 로고    scopus 로고
    • TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer Cells
    • doi:10.1021/pr400457u
    • Hekmat O, Munk S, Fogh L, Yadav R, Francavilla C, Horn H, et al. TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer Cells. Journal of proteome research. 2013; 12: 4136-51. doi:10.1021/pr400457u.
    • (2013) Journal of proteome research , vol.12 , pp. 4136-4151
    • Hekmat, O.1    Munk, S.2    Fogh, L.3    Yadav, R.4    Francavilla, C.5    Horn, H.6
  • 99
    • 84877151366 scopus 로고    scopus 로고
    • TIMP-1 overexpression does not affect sensitivity to HER2-targeting drugs in the HER2-gene-amplified SK-BR-3 human breast cancer cell line Tumour biology
    • doi:10.1007/s13277-013-0659-5
    • Deng X, Fogh L, Lademann U, Jensen V, Stenvang J, Yang H, et al. TIMP-1 overexpression does not affect sensitivity to HER2-targeting drugs in the HER2-gene-amplified SK-BR-3 human breast cancer cell line. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2013; 34: 1161-70. doi:10.1007/s13277-013-0659-5.
    • (2013) The journal of the International Society for Oncodevelopmental Biology and Medicine , vol.34 , pp. 1161-1170
    • Deng, X.1    Fogh, L.2    Lademann, U.3    Jensen, V.4    Stenvang, J.5    Yang, H.6
  • 100
    • 77049099101 scopus 로고    scopus 로고
    • Lin28 A microRNA regulator with a macro role
    • doi:10.1016/j.cell.2010.02.007
    • Viswanathan SR, Daley GQ. Lin28: A microRNA regulator with a macro role. Cell. 2010; 140: 445-9. doi:10.1016/j.cell.2010.02.007.
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 101
    • 84864568178 scopus 로고    scopus 로고
    • HER2, two stem cell regulators conspire to drive aggressive breast cancer
    • doi:10.4161/cc.21395
    • Malik F, Korkaya H, Clouthier SG, Wicha MS. Lin28 and HER2: two stem cell regulators conspire to drive aggressive breast cancer. Cell cycle. 2012; 11: 2780-1. doi:10.4161/cc.21395.
    • (2012) Cell cycle , vol.11 , pp. 2780-2781
    • Malik, F.1    Korkaya, H.2    Clouthier, S.G.3    Wicha, M.S.4    Lin28, H.5
  • 102
    • 67649881121 scopus 로고    scopus 로고
    • Lin28 promotes transformation and is associated with advanced human malignancies
    • doi:10.1038/ng.392
    • Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nature genetics. 2009; 41: 843-8. doi:10.1038/ng.392.
    • (2009) Nature genetics , vol.41 , pp. 843-848
    • Viswanathan, S.R.1    Powers, J.T.2    Einhorn, W.3    Hoshida, Y.4    Ng, T.L.5    Toffanin, S.6
  • 103
    • 84863613073 scopus 로고    scopus 로고
    • Lin28 mediates paclitaxel resistance by modulating p21 Rb and Let-7a miRNA in breast cancer cells.
    • doi:10.1371/journal.pone.0040008
    • Lv K, Liu L, Wang L, Yu J, Liu X, Cheng Y, et al. Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells. PloS one. 2012; 7: e40008. doi:10.1371/journal.pone.0040008.
    • (2012) PloS one. , vol.7
    • Lv, K.1    Liu, L.2    Wang, L.3    Yu, J.4    Liu, X.5    Cheng, Y.6
  • 104
    • 84879261337 scopus 로고    scopus 로고
    • Lin28 mediates radiation resistance of breast cancer cells via regulation of caspase H2A. X and Let-7 signaling.
    • doi:10.1371/journal.pone.0067373
    • Wang L, Yuan C, Lv K, Xie S, Fu P, Liu X, et al. Lin28 mediates radiation resistance of breast cancer cells via regulation of caspase, H2A.X and Let-7 signaling. PloS one. 2013; 8: e67373. doi:10.1371/journal.pone.0067373.
    • (2013) PloS one. , vol.8
    • Wang, L.1    Yuan, C.2    Lv, K.3    Xie, S.4    Fu, P.5    Liu, X.6
  • 105
    • 72049101611 scopus 로고    scopus 로고
    • Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras. International
    • doi:10.1016/j.ijrobp.2009.08.028
    • Oh JS, Kim JJ, Byun JY, Kim IA. Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras. International journal of radiation oncology, biology, physics. 2010; 76: 5-8. doi:10.1016/j.ijrobp.2009.08.028.
    • (2010) journal of radiation oncology, biology, physics , vol.76 , pp. 5-8
    • Oh, J.S.1    Kim, J.J.2    Byun, J.Y.3    Kim, I.A.4
  • 106
    • 0027751663 scopus 로고
    • elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993; 75: 843-54.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3    The, C.4
  • 107
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs, genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116: 281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 108
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs, target recognition and regulatory functions
    • doi:10.1016/j.cell.2009.01.002
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009; 136: 215-33. doi:10.1016/j.cell.2009.01.002.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 109
    • 65549126290 scopus 로고    scopus 로고
    • MicroRNA, mechanism of gene regulation and application to livestock
    • doi:10.2527/jas.2008-1303.
    • McDaneld TG. MicroRNA: mechanism of gene regulation and application to livestock. Journal of animal science. 2009; 87: E21-8. doi:10.2527/jas.2008-1303.
    • (2009) Journal of animal science , vol.87
    • McDaneld, T.G.1
  • 111
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • doi:10.1038/nature03702
    • Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature. 2005; 435: 834-8. doi:10.1038/nature03702.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3    Alvarez-Saavedra, E.4    Lamb, J.5    Peck, D.6
  • 112
    • 79958767367 scopus 로고    scopus 로고
    • MicroRNA signatures, clinical biomarkers for the diagnosis and treatment of breast cancer
    • doi:10.1016/j.molmed.2011.01.006
    • Andorfer CA, Necela BM, Thompson EA, Perez EA. MicroRNA signatures: clinical biomarkers for the diagnosis and treatment of breast cancer. Trends in molecular medicine. 2011; 17: 313-9. doi:10.1016/j.molmed.2011.01.006.
    • (2011) Trends in molecular medicine , vol.17 , pp. 313-319
    • Andorfer, C.A.1    Necela, B.M.2    Thompson, E.A.3    Perez, E.A.4
  • 113
    • 77649138141 scopus 로고    scopus 로고
    • Circulating microRNAs as novel minimally invasive biomarkers for breast cancer
    • doi:10.1097/SLA.0b013e3181cc939f
    • Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Newell J, Kerin MJ. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Annals of surgery. 2010; 251: 499-505. doi:10.1097/SLA.0b013e3181cc939f.
    • (2010) Annals of surgery , vol.251 , pp. 499-505
    • Heneghan, H.M.1    Miller, N.2    Lowery, A.J.3    Sweeney, K.J.4    Newell, J.5    Kerin, M.J.6
  • 114
    • 77956117169 scopus 로고    scopus 로고
    • Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease
    • doi:10.1634/theoncologist.2010-0103
    • Heneghan HM, Miller N, Kelly R, Newell J, Kerin MJ. Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease. The oncologist. 2010; 15: 673-82. doi:10.1634/theoncologist.2010-0103.
    • (2010) The oncologist , vol.15 , pp. 673-682
    • Heneghan, H.M.1    Miller, N.2    Kelly, R.3    Newell, J.4    Kerin, M.J.5
  • 115
    • 84892926734 scopus 로고    scopus 로고
    • Searching for candidate microRNA biomarkers in detection of breast cancer, a meta-analysis
    • doi:10.3233/CBM-130379
    • Lv M, Zhu X, Chen W, Zhao J, Tang J. Searching for candidate microRNA biomarkers in detection of breast cancer: a meta-analysis. Cancer biomarkers: section A of Disease markers. 2013; 13: 395-401. doi:10.3233/CBM-130379.
    • (2013) Cancer biomarkers, section A of Disease markers , vol.13 , pp. 395-401
    • Lv, M.1    Zhu, X.2    Chen, W.3    Zhao, J.4    Tang, J.5
  • 117
    • 79956313718 scopus 로고    scopus 로고
    • Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
    • doi:10.1074/jbc. M110.216887
    • Gong C, Yao Y, Wang Y, Liu B, Wu W, Chen J, et al. Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer. The Journal of biological chemistry. 2011; 286: 19127-37. doi:10.1074/jbc. M110.216887.
    • (2011) The Journal of biological chemistry , vol.286 , pp. 19127-19137
    • Gong, C.1    Yao, Y.2    Wang, Y.3    Liu, B.4    Wu, W.5    Chen, J.6
  • 118
    • 84882726021 scopus 로고    scopus 로고
    • MicroRNA-21, a therapeutic target for reversing drug resistance in cancer
    • doi:10.1517/14728222.2013.819853
    • Hong L, Han Y, Zhang Y, Zhang H, Zhao Q, Wu K, et al. MicroRNA-21: a therapeutic target for reversing drug resistance in cancer. Expert opinion on therapeutic targets. 2013; 17: 1073-80. doi:10.1517/14728222.2013.819853.
    • (2013) Expert opinion on therapeutic targets , vol.17 , pp. 1073-1080
    • Hong, L.1    Han, Y.2    Zhang, Y.3    Zhang, H.4    Zhao, Q.5    Wu, K.6
  • 119
    • 70349576204 scopus 로고    scopus 로고
    • Interactions between the estrogen receptor, its cofactors and microRNAs in breast cancer
    • doi:10.1007/s10549-009-0429-7
    • McCafferty MP, McNeill RE, Miller N, Kerin MJ. Interactions between the estrogen receptor, its cofactors and microRNAs in breast cancer. Breast cancer research and treatment. 2009; 116: 425-32. doi:10.1007/s10549-009-0429-7.
    • (2009) Breast cancer research and treatment , vol.116 , pp. 425-432
    • McCafferty, M.P.1    McNeill, R.E.2    Miller, N.3    Kerin, M.J.4
  • 121
    • 84879767780 scopus 로고    scopus 로고
    • Multigene assays and molecular markers in breast cancer, systematic review of health economic analyses
    • doi:10.1007/s10549-013-2559-1
    • Rouzier R, Pronzato P, Chereau E, Carlson J, Hunt B, Valentine WJ. Multigene assays and molecular markers in breast cancer: systematic review of health economic analyses. Breast cancer research and treatment. 2013; 139: 621-37. doi:10.1007/s10549-013-2559-1.
    • (2013) Breast cancer research and treatment , vol.139 , pp. 621-637
    • Rouzier, R.1    Pronzato, P.2    Chereau, E.3    Carlson, J.4    Hunt, B.5    Valentine, W.J.6
  • 122
    • 70450213750 scopus 로고    scopus 로고
    • Economic analysis of gene expression profile data to guide adjuvant treatment in women with early-stage breast cancer
    • doi:10.3109/07357900903275217
    • Cosler LE, Lyman GH. Economic analysis of gene expression profile data to guide adjuvant treatment in women with early-stage breast cancer. Cancer investigation. 2009; 27: 953-9. doi:10.3109/07357900903275217.
    • (2009) Cancer investigation , vol.27 , pp. 953-959
    • Cosler, L.E.1    Lyman, G.H.2
  • 125
    • 79958265641 scopus 로고    scopus 로고
    • Economic evaluation of the 21-gene signature (Oncotype DX) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TR03)
    • doi:10.1007/s10549-010-1243-y
    • Kondo M, Hoshi SL, Yamanaka T, Ishiguro H, Toi M. Economic evaluation of the 21-gene signature (Oncotype DX) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TR03). Breast cancer research and treatment. 2011; 127: 739-49. doi:10.1007/s10549-010-1243-y.
    • (2011) Breast cancer research and treatment , vol.127 , pp. 739-749
    • Kondo, M.1    Hoshi, S.L.2    Yamanaka, T.3    Ishiguro, H.4    Toi, M.5
  • 126
    • 79957823551 scopus 로고    scopus 로고
    • Cost-effectiveness of 70-gene MammaPrint signature in node-negative breast cancer
    • Chen E, Tong KB, Malin JL. Cost-effectiveness of 70-gene MammaPrint signature in node-negative breast cancer. The American journal of managed care. 2010; 16: e333-42.
    • (2010) The American journal of managed care , vol.16
    • Chen, E.1    Tong, K.B.2    Malin, J.L.3
  • 127
    • 77951938304 scopus 로고    scopus 로고
    • Cost-effectiveness of the 70-gene signature versus St Gallen guidelines and Adjuvant Online for early breast cancer
    • doi:10.1016/j.ejca.2010.02.035
    • Retel VP, Joore MA, Knauer M, Linn SC, Hauptmann M, Harten WH. Cost-effectiveness of the 70-gene signature versus St. Gallen guidelines and Adjuvant Online for early breast cancer. European journal of cancer. 2010; 46: 1382-91. doi:10.1016/j.ejca.2010.02.035
    • (2010) European journal of cancer , vol.46 , pp. 1382-1391
    • Retel, V.P.1    Joore, M.A.2    Knauer, M.3    Linn, S.C.4    Hauptmann, M.5    Harten, W.H.6


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