메뉴 건너뛰기




Volumn 11, Issue 1, 2013, Pages 31-42

STAT3-RANTES autocrine signaling is essential for tamoxifen resistance in human breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL 2; RANTES; STAT3 PROTEIN; TAMOXIFEN;

EID: 84873033728     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-12-0217     Document Type: Article
Times cited : (70)

References (51)
  • 2
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG0
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005;365:1687-717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 3
    • 0037373326 scopus 로고    scopus 로고
    • Elevated levels of epidermal growth factor receptor/cerbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells
    • Knowlden JM, Hutcheson IR, Jones HE, Madden T, Gee JM, Harper ME, et al. Elevated levels of epidermal growth factor receptor/cerbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells. Endocrinology 2003;144: 1032-44.
    • (2003) Endocrinology , vol.144 , pp. 1032-1044
    • Knowlden, J.M.1    Hutcheson, I.R.2    Jones, H.E.3    Madden, T.4    Gee, J.M.5    Harper, M.E.6
  • 4
    • 17844398046 scopus 로고    scopus 로고
    • Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase
    • Gutierrez MC, Detre S, Johnston S, Mohsin SK, Shou J, Allred DC, et al. Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase. J Clin Oncol 2005;23:2469-76.
    • (2005) J Clin Oncol , vol.23 , pp. 2469-2476
    • Gutierrez, M.C.1    Detre, S.2    Johnston, S.3    Mohsin, S.K.4    Shou, J.5    Allred, D.C.6
  • 5
    • 0034690750 scopus 로고    scopus 로고
    • UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years
    • Peto R, Boreham J, Clarke M, Davies C, Beral V. UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years. Lancet 2000;355:1822.
    • (2000) Lancet , vol.355 , pp. 1822
    • Peto, R.1    Boreham, J.2    Clarke, M.3    Davies, C.4    Beral, V.5
  • 7
    • 28844494352 scopus 로고    scopus 로고
    • Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation
    • Hiscox S, Jiang WG, Obermeier K, Taylor K, Morgan L, Burmi R, et al. Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation. Int J Cancer 2006;118:290-301.
    • (2006) Int J Cancer , vol.118 , pp. 290-301
    • Hiscox, S.1    Jiang, W.G.2    Obermeier, K.3    Taylor, K.4    Morgan, L.5    Burmi, R.6
  • 8
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg J, Darnell JE Jr. The role of STATs in transcriptional control and their impact on cellular function. Oncogene 2000;19: 2468-73.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell Jr., J.E.2
  • 9
    • 31544460437 scopus 로고    scopus 로고
    • Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression
    • Diaz N, Minton S, Cox C, Bowman T, Gritsko T, Garcia R, et al. Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression. Clin Cancer Res 2006;12:20-8.
    • (2006) Clin Cancer Res , vol.12 , pp. 20-28
    • Diaz, N.1    Minton, S.2    Cox, C.3    Bowman, T.4    Gritsko, T.5    Garcia, R.6
  • 10
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994;264:95-8.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 11
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in antiapoptosis
    • Fukada T, Hibi M, Yamanaka Y, Takahashi-Tezuka M, Fujitani Y, Yamaguchi T, et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in antiapoptosis. Immunity 1996;5:449-60.
    • (1996) Immunity , vol.5 , pp. 449-460
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3    Takahashi-Tezuka, M.4    Fujitani, Y.5    Yamaguchi, T.6
  • 14
    • 0037112367 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
    • Mora LB, Buettner R, Seigne J, Diaz J, Ahmad N, Garcia R, et al. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 2002;62:6659-66.
    • (2002) Cancer Res , vol.62 , pp. 6659-6666
    • Mora, L.B.1    Buettner, R.2    Seigne, J.3    Diaz, J.4    Ahmad, N.5    Garcia, R.6
  • 15
    • 0037316938 scopus 로고    scopus 로고
    • Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis
    • Dolled-Filhart M, Camp RL, Kowalski DP, Smith BL, Rimm DL. Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis. Clin Cancer Res 2003;9:594-600.
    • (2003) Clin Cancer Res , vol.9 , pp. 594-600
    • Dolled-Filhart, M.1    Camp, R.L.2    Kowalski, D.P.3    Smith, B.L.4    Rimm, D.L.5
  • 16
    • 0036569522 scopus 로고    scopus 로고
    • Activation of Stat-3 as one of the early events in tobacco chewing - Mediated oral carcinogenesis
    • Nagpal JK, Mishra R, Das BR. Activation of Stat-3 as one of the early events in tobacco chewing - Mediated oral carcinogenesis. Cancer 2002;94:2393-400.
    • (2002) Cancer , vol.94 , pp. 2393-2400
    • Nagpal, J.K.1    Mishra, R.2    Das, B.R.3
  • 17
    • 0041620205 scopus 로고    scopus 로고
    • Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis
    • Hsiao JR, Jin YT, Tsai ST, Shiau AL, Wu CL, Su WC. Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis. Br J Cancer 2003;89:344-9.
    • (2003) Br J Cancer , vol.89 , pp. 344-349
    • Hsiao, J.R.1    Jin, Y.T.2    Tsai, S.T.3    Shiau, A.L.4    Wu, C.L.5    Su, W.C.6
  • 18
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 2002;8:945-54.
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 19
    • 0034658499 scopus 로고    scopus 로고
    • STAT signaling in head and neck cancer
    • Song JI, Grandis JR. STAT signaling in head and neck cancer. Oncogene 2000;19:2489-95.
    • (2000) Oncogene , vol.19 , pp. 2489-2495
    • Song, J.I.1    Grandis, J.R.2
  • 21
    • 0037124102 scopus 로고    scopus 로고
    • Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines
    • Li L, Shaw PE. Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines. J Biol Chem 2002;277:17397-405.
    • (2002) J Biol Chem , vol.277 , pp. 17397-17405
    • Li, L.1    Shaw, P.E.2
  • 22
    • 20844444135 scopus 로고    scopus 로고
    • Targeting Stat3 in cancer therapy
    • Jing N, Tweardy DJ. Targeting Stat3 in cancer therapy. Anti Cancer Drug 2005;16:601-7.
    • (2005) Anti Cancer Drug , vol.16 , pp. 601-607
    • Jing, N.1    Tweardy, D.J.2
  • 24
    • 0033568215 scopus 로고    scopus 로고
    • Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma
    • Luboshits G, Shina S, Kaplan O, Engelberg S, Nass D, Lifshitz-Mercer B, et al. Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma. Cancer Res 1999;59:4681-7.
    • (1999) Cancer Res , vol.59 , pp. 4681-4687
    • Luboshits, G.1    Shina, S.2    Kaplan, O.3    Engelberg, S.4    Nass, D.5    Lifshitz-Mercer, B.6
  • 25
    • 0035120421 scopus 로고    scopus 로고
    • Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer
    • Niwa Y, Akamatsu H, Niwa H, Sumi H, Ozaki Y, Abe A. Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer. Clin Cancer Res 2001;7:285-9.
    • (2001) Clin Cancer Res , vol.7 , pp. 285-289
    • Niwa, Y.1    Akamatsu, H.2    Niwa, H.3    Sumi, H.4    Ozaki, Y.5    Abe, A.6
  • 26
    • 6044230918 scopus 로고    scopus 로고
    • Molecular profiling of inflammatory breast cancer: Identification of a poorprognosis gene expression signature
    • Bieche I, Lerebours F, Tozlu S, Espie M, Marty M, Lidereau R. Molecular profiling of inflammatory breast cancer: identification of a poorprognosis gene expression signature. Clin Cancer Res 2004;10:6789- 95.
    • (2004) Clin Cancer Res , vol.10 , pp. 6789-6795
    • Bieche, I.1    Lerebours, F.2    Tozlu, S.3    Espie, M.4    Marty, M.5    Lidereau, R.6
  • 27
    • 52949094598 scopus 로고    scopus 로고
    • Concomitant expression of the chemokines RANTES and MCP-1 in human breast cancer: A basis for tumor-promoting interactions
    • Soria G, Yaal-Hahoshen N, Azenshtein E, Shina S, Leider-Trejo L, Ryvo L, et al. Concomitant expression of the chemokines RANTES and MCP-1 in human breast cancer: a basis for tumor-promoting interactions. Cytokine 2008;44:191-200.
    • (2008) Cytokine , vol.44 , pp. 191-200
    • Soria, G.1    Yaal-Hahoshen, N.2    Azenshtein, E.3    Shina, S.4    Leider-Trejo, L.5    Ryvo, L.6
  • 28
    • 0033021558 scopus 로고    scopus 로고
    • The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice
    • Mrowietz U, Schwenk U, Maune S, Bartels J, Kupper M, Fichtner I, et al. The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice. Br J Cancer 1999;79:1025-31.
    • (1999) Br J Cancer , vol.79 , pp. 1025-1031
    • Mrowietz, U.1    Schwenk, U.2    Maune, S.3    Bartels, J.4    Kupper, M.5    Fichtner, I.6
  • 29
    • 34547781742 scopus 로고    scopus 로고
    • Induction of multidrug resistance associated protein 2 in tamoxifen-resistant breast cancer cells
    • Choi HK, Yang JW, Roh SH, Han CY, Kang KW. Induction of multidrug resistance associated protein 2 in tamoxifen-resistant breast cancer cells. Endocr Relat Cancer 2007;14:293-303.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 293-303
    • Choi, H.K.1    Yang, J.W.2    Roh, S.H.3    Han, C.Y.4    Kang, K.W.5
  • 30
    • 0031800697 scopus 로고    scopus 로고
    • Activation of STAT transcription factors in oncogenic tyrosine kinase signaling
    • Garcia R, Jove R. Activation of STAT transcription factors in oncogenic tyrosine kinase signaling. J Biomed Sci 1998;5:79-85.
    • (1998) J Biomed Sci , vol.5 , pp. 79-85
    • Garcia, R.1    Jove, R.2
  • 32
    • 0028923658 scopus 로고
    • Elevated levels of members of the Stat family of transcription factors in breast-carcinoma nuclear extracts
    • Watson CJ, Miller WR. Elevated levels of members of the Stat family of transcription factors in breast-carcinoma nuclear extracts. Br J Cancer 1995;71:840-4.
    • (1995) Br J Cancer , vol.71 , pp. 840-844
    • Watson, C.J.1    Miller, W.R.2
  • 33
    • 23744481633 scopus 로고    scopus 로고
    • Evaluation of potential Stat3-regulated genes in human breast cancer
    • Hsieh FC, Cheng G, Lin J. Evaluation of potential Stat3-regulated genes in human breast cancer. Biochem Biophys Res Commun 2005;335:292-9.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 292-299
    • Hsieh, F.C.1    Cheng, G.2    Lin, J.3
  • 34
    • 68549126713 scopus 로고    scopus 로고
    • Implication of protein tyrosine phosphatase 1B in MCF-7 cell proliferation and resistance to 4-OH tamoxifen
    • Blanquart C, Karouri SE, Issad T. Implication of protein tyrosine phosphatase 1B in MCF-7 cell proliferation and resistance to 4-OH tamoxifen. Biochem Biophys Res Commun 2009;387:748-53.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 748-753
    • Blanquart, C.1    Karouri, S.E.2    Issad, T.3
  • 35
    • 0034219458 scopus 로고    scopus 로고
    • Elevated phosphorylation of AKT and Stat3 in prostate, breast, and cervical cancer cells
    • Page C, Huang M, Jin XH, Cho K, Lilja J, Reynolds RK, et al. Elevated phosphorylation of AKT and Stat3 in prostate, breast, and cervical cancer cells. Int J Oncol 2000;17:23-8.
    • (2000) Int J Oncol , vol.17 , pp. 23-28
    • Page, C.1    Huang, M.2    Jin, X.H.3    Cho, K.4    Lilja, J.5    Reynolds, R.K.6
  • 37
    • 0344873744 scopus 로고    scopus 로고
    • Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines
    • DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao SJ, et al. Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines. Oncogene 2003;22:7781-95.
    • (2003) Oncogene , vol.22 , pp. 7781-7795
    • Dearmond, D.1    Brattain, M.G.2    Jessup, J.M.3    Kreisberg, J.4    Malik, S.5    Zhao, S.J.6
  • 38
    • 57349090717 scopus 로고    scopus 로고
    • LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression
    • Kim JE, Kim HS, Shin YJ, Lee CS, Won C, Lee SA, et al. LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression. Exp Mol Med 2008;40:514-22.
    • (2008) Exp Mol Med , vol.40 , pp. 514-522
    • Kim, J.E.1    Kim, H.S.2    Shin, Y.J.3    Lee, C.S.4    Won, C.5    Lee, S.A.6
  • 39
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007;449:557-63.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3    Sullivan, A.4    Brooks, M.W.5    Bell, G.W.6
  • 40
    • 74949108144 scopus 로고    scopus 로고
    • Stat3- dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice
    • Kovacic JC, Gupta R, Lee AC, Ma MC, Fang F, Tolbert CN, et al. Stat3- dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice. J Clin Invest 2010;120:303-14.
    • (2010) J Clin Invest , vol.120 , pp. 303-314
    • Kovacic, J.C.1    Gupta, R.2    Lee, A.C.3    Ma, M.C.4    Fang, F.5    Tolbert, C.N.6
  • 41
    • 34249868449 scopus 로고    scopus 로고
    • Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NF kappa B
    • Yang JB, Liao XD, Agarwal MK, Barnes L, Auron PE, Stark GR. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NF kappa B. Gene Dev 2007; 21:1396-408.
    • (2007) Gene Dev , vol.21 , pp. 1396-1408
    • Yang, J.B.1    Liao, X.D.2    Agarwal, M.K.3    Barnes, L.4    Auron, P.E.5    Stark, G.R.6
  • 44
    • 34249008543 scopus 로고    scopus 로고
    • Expression of a peroxisomeproliferator-activated receptor gamma 1 splice variant that was identified in human lung cancers suppresses cell death induced by cisplatin and oxidative stress
    • Kim HJ, Hwang JY, Kim HJ, Choi WS, Lee JH, Kim HJ, et al. Expression of a peroxisomeproliferator-activated receptor gamma 1 splice variant that was identified in human lung cancers suppresses cell death induced by cisplatin and oxidative stress. Clin Cancer Res 2007; 13:2577-83.
    • (2007) Clin Cancer Res , vol.13 , pp. 2577-2583
    • Kim, H.J.1    Hwang, J.Y.2    Kim, H.J.3    Choi, W.S.4    Lee, J.H.5    Kim, H.J.6
  • 45
    • 77953750777 scopus 로고    scopus 로고
    • Beta III-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer
    • McCarroll JA, Gan PP, Liu M, Kavallaris M. beta III-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer. Cancer Res 2010;70:4995-5003.
    • (2010) Cancer Res , vol.70 , pp. 4995-5003
    • McCarroll, J.A.1    Gan, P.P.2    Liu, M.3    Kavallaris, M.4
  • 46
    • 0037441888 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
    • Aoki Y, Feldman GM, Tosato G. Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. Blood 2003;101:1535-42.
    • (2003) Blood , vol.101 , pp. 1535-1542
    • Aoki, Y.1    Feldman, G.M.2    Tosato, G.3
  • 47
    • 0037206950 scopus 로고    scopus 로고
    • Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
    • Real PJ, Sierra A, de Juan A, Segovia JC, Lopez-Vega JM, Fernandez-Luna JL. Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. Oncogene 2002; 21:7611-8.
    • (2002) Oncogene , vol.21 , pp. 7611-7618
    • Real, P.J.1    Sierra, A.2    De Juan, A.3    Segovia, J.C.4    Lopez-Vega, J.M.5    Fernandez-Luna, J.L.6
  • 48
    • 31544458469 scopus 로고    scopus 로고
    • Persistent activation of Stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells
    • Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, Huang M, et al. Persistent activation of Stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells. Clin Cancer Res 2006;12:11-9.
    • (2006) Clin Cancer Res , vol.12 , pp. 11-19
    • Gritsko, T.1    Williams, A.2    Turkson, J.3    Kaneko, S.4    Bowman, T.5    Huang, M.6
  • 50
    • 0032702168 scopus 로고    scopus 로고
    • P38 MAP kinase regulates RANTES production by TNF-alpha-stimulated human pulmonary vascular endothelial cells
    • Hashimoto S, Gon Y, Asai Y, Machino T, Jibiki I, Takeshita I, et al. p38 MAP kinase regulates RANTES production by TNF-alpha-stimulated human pulmonary vascular endothelial cells. Allergy 1999;54: 1168-72.
    • (1999) Allergy , vol.54 , pp. 1168-1172
    • Hashimoto, S.1    Gon, Y.2    Asai, Y.3    MacHino, T.4    Jibiki, I.5    Takeshita, I.6
  • 51
    • 0035815672 scopus 로고    scopus 로고
    • Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells
    • Wong M, Uddin S, Majchrzak B, Huynh T, Proudfoot AE, Platanias LC, et al. Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells. J Biol Chem 2001;276: 11427-31.
    • (2001) J Biol Chem , vol.276 , pp. 11427-11431
    • Wong, M.1    Uddin, S.2    Majchrzak, B.3    Huynh, T.4    Proudfoot, A.E.5    Platanias, L.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.