-
1
-
-
0024593647
-
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells
-
R. Khokha, P. Waterhouse, S. Yagel, P. K. Lala, C. M. Overall, G. Norton, D. T. Denhardt, Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. Science 243, 947-950 (1989).
-
(1989)
Science
, vol.243
, pp. 947-950
-
-
Khokha, R.1
Waterhouse, P.2
Yagel, S.3
Lala, P.K.4
Overall, C.M.5
Norton, G.6
Denhardt, D.T.7
-
2
-
-
0025778347
-
Tumor cell invasion inhibited by TIMP-2
-
A. Albini, A. Melchiori, L. Santi, L. A. Liotta, P. D. Brown, W. G. Stetler-Stevenson, Tumor cell invasion inhibited by TIMP-2. J. Natl. Cancer Inst. 83, 775-779 (1991).
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 775-779
-
-
Albini, A.1
Melchiori, A.2
Santi, L.3
Liotta, L.A.4
Brown, P.D.5
Stetler-Stevenson, W.G.6
-
3
-
-
0025238632
-
Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases
-
O. A. Alvarez, D. F. Carmichael, Y. A. DeClerck, Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases. J. Natl. Cancer Inst. 82, 589-595 (1990).
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 589-595
-
-
Alvarez, O.A.1
Carmichael, D.F.2
Declerck, Y.A.3
-
4
-
-
0026573378
-
Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases
-
Y. A. DeClerck, N. Perez, H. Shimada, T. C. Boone, K. E. Langley, S. M. Taylor, Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res. 52, 701-708 (1992).
-
(1992)
Cancer Res
, vol.52
, pp. 701-708
-
-
Declerck, Y.A.1
Perez, N.2
Shimada, H.3
Boone, T.C.4
Langley, K.E.5
Taylor, S.M.6
-
5
-
-
0028104790
-
Effect of tissue inhibitor of the matrix metalloproteinases- 2 expression on the growth and spontaneous metastasis of a human melanoma cell line
-
A. M. Montgomery, B. M. Mueller, R. A. Reisfeld, S. M. Taylor, Y. A. DeClerck, Effect of tissue inhibitor of the matrix metalloproteinases- 2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res. 54, 5467-5473 (1994).
-
(1994)
Cancer Res
, vol.54
, pp. 5467-5473
-
-
Montgomery, A.M.1
Mueller, B.M.2
Reisfeld, R.A.3
Taylor, S.M.4
Declerck, Y.A.5
-
6
-
-
0000517074
-
Matrix metalloproteinase inhibitors
-
P. D. Brown, Matrix metalloproteinase inhibitors. Angiogenesis 1, 142-154 (1998).
-
(1998)
Angiogenesis
, vol.1
, pp. 142-154
-
-
Brown, P.D.1
-
7
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
L. M. Coussens, B. Fingleton, L. M. Matrisian, Matrix metalloproteinase inhibitors and cancer: Trials and tribulations. Science 295, 2387-2392 (2002).
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
8
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
M. Egeblad, Z. Werb, New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2, 161-174 (2002).
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
9
-
-
1342279517
-
TIMPs as multifacial proteins
-
E. Lambert, E. Dassé, B. Haye, E. Petitfrère, TIMPs as multifacial proteins. Crit. Rev. Oncol. Hematol. 49, 187-198 (2004).
-
(2004)
Crit. Rev. Oncol. Hematol.
, vol.49
, pp. 187-198
-
-
Lambert, E.1
Dassé, E.2
Haye, B.3
Petitfrère, E.4
-
10
-
-
0345737132
-
The TIMPs tango with MMPs and more in the central nervous system
-
S. J. Crocker, A. Pagenstecher, I. L. Campbell, The TIMPs tango with MMPs and more in the central nervous system. J. Neurosci. Res. 75, 1-11 (2004).
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 1-11
-
-
Crocker, S.J.1
Pagenstecher, A.2
Campbell, I.L.3
-
11
-
-
0034615550
-
Tissue inhibitors of metalloproteinases: Evolution, structure and function
-
K. Brew, D. Dinakarpandian, H. Nagase, Tissue inhibitors of metalloproteinases: Evolution, structure and function. Biochim. Biophys. Acta 1477, 267-283 (2000).
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, pp. 267-283
-
-
Brew, K.1
Dinakarpandian, D.2
Nagase, H.3
-
12
-
-
29244488777
-
Tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice display motor deficits
-
D. M. Jaworski, P. Soloway, J. Caterina, W. A. Falls, Tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice display motor deficits. J. Neurobiol. 66, 82-94 (2006).
-
(2006)
J. Neurobiol.
, vol.66
, pp. 82-94
-
-
Jaworski, D.M.1
Soloway, P.2
Caterina, J.3
Falls, W.A.4
-
13
-
-
0042829226
-
The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos
-
J. S. Zhang, S. Bai, C. Tanase, H. Nagase, M. P. Sarras, The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos. Dev. Genes Evol. 213, 382-389 (2003).
-
(2003)
Dev. Genes Evol.
, vol.213
, pp. 382-389
-
-
Zhang, J.S.1
Bai, S.2
Tanase, C.3
Nagase, H.4
Sarras, M.P.5
-
14
-
-
0041885435
-
A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis
-
S. E. Gill, M. C. Pape, R. Khokha, A. J. Watson, K. J. Leco, A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Dev. Biol. 261, 313-323 (2003).
-
(2003)
Dev. Biol.
, vol.261
, pp. 313-323
-
-
Gill, S.E.1
Pape, M.C.2
Khokha, R.3
Watson, A.J.4
Leco, K.J.5
-
15
-
-
0034823461
-
Accelerated apoptosis in the Timp- 3-deficient mammary gland
-
J. E. Fata, K. J. Leco, E. B. Voura, H. Y. Yu, P. Waterhouse, G. Murphy, R. A. Moorehead, R. Khokha, Accelerated apoptosis in the Timp- 3-deficient mammary gland. J. Clin. Invest. 108, 831-841 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 831-841
-
-
Fata, J.E.1
Leco, K.J.2
Voura, E.B.3
Yu, H.Y.4
Waterhouse, P.5
Murphy, G.6
Moorehead, R.A.7
Khokha, R.8
-
16
-
-
0033861140
-
Inflated wings, tissue autolysis and early death in tissue inhibitor of metalloproteinases mutants of Drosophila
-
T. A. Godenschwege, N. Pohar, S. Buchner, E. Buchner, Inflated wings, tissue autolysis and early death in tissue inhibitor of metalloproteinases mutants of Drosophila. Eur. J. Cell Biol. 79, 495-501 (2000).
-
(2000)
Eur. J. Cell Biol.
, vol.79
, pp. 495-501
-
-
Godenschwege, T.A.1
Pohar, N.2
Buchner, S.3
Buchner, E.4
-
17
-
-
0032509104
-
Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution
-
A. Tuuttila, E. Morgunova, U. Bergmann, Y. Lindqvist, K. Maskos, C. Fernandez-Catalan, W. Bode, K. Tryggvason, G. Schneider, Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution. J. Mol. Biol. 284, 1133-1140 (1998).
-
(1998)
J. Mol. Biol.
, vol.284
, pp. 1133-1140
-
-
Tuuttila, A.1
Morgunova, E.2
Bergmann, U.3
Lindqvist, Y.4
Maskos, K.5
Fernandez-Catalan, C.6
Bode, W.7
Tryggvason, K.8
Schneider, G.9
-
18
-
-
0036800192
-
Metalloproteinase inhibitors: Biological actions and therapeutic opportunities
-
A. H. Baker, D. R. Edwards, G. Murphy, Metalloproteinase inhibitors: Biological actions and therapeutic opportunities. J. Cell Sci. 115, 3719-3727 (2002).
-
(2002)
J. Cell Sci.
, vol.115
, pp. 3719-3727
-
-
Baker, A.H.1
Edwards, D.R.2
Murphy, G.3
-
19
-
-
0032508675
-
TNF-〈 converting enzyme (TACE) is inhibited by TIMP-3
-
A. Amour, P. M. Slocombe, A. Webster, M. Butler, C. G. Knight, B. J. Smith, P. E. Stephens, C. Shelley, M. Hutton, V. Knauper, A. J. Docherty, G. Murphy, TNF-〈 converting enzyme (TACE) is inhibited by TIMP-3. FEBS Lett. 435, 39-44 (1998).
-
(1998)
FEBS Lett
, vol.435
, pp. 39-44
-
-
Amour, A.1
Slocombe, P.M.2
Webster, A.3
Butler, M.4
Knight, C.G.5
Smith, B.J.6
Stephens, P.E.7
Shelley, C.8
Hutton, M.9
Knauper, V.10
Docherty, A.J.11
Murphy, G.12
-
20
-
-
0033134622
-
Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
-
W. G. Stetler-Stevenson, Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention. J. Clin. Invest. 103, 1237-1241 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1237-1241
-
-
Stetler-Stevenson, W.G.1
-
21
-
-
0034613296
-
TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix
-
W. H. Yu, S. Yu, Q. Meng, K. Brew, J. F. Woessner Jr., TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix. J. Biol. Chem. 275, 31226-31232 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31226-31232
-
-
Yu, W.H.1
Yu, S.2
Meng, Q.3
Brew, K.4
Woessner Jr., J.F.5
-
23
-
-
1842737700
-
Expression analysis of the entire MMP and TIMP gene families during mouse tissue development
-
R. K. Nuttall, C. L. Sampieri, C. J. Pennington, S. E. Gill, G. A. Schultz, D. R. Edwards, Expression analysis of the entire MMP and TIMP gene families during mouse tissue development. FEBS Lett. 563, 129-134 (2004).
-
(2004)
FEBS Lett
, vol.563
, pp. 129-134
-
-
Nuttall, R.K.1
Sampieri, C.L.2
Pennington, C.J.3
Gill, S.E.4
Schultz, G.A.5
Edwards, D.R.6
-
24
-
-
0030885016
-
Tissue inhibitor of metalloproteinases-2 is expressed in the interstitial matrix in adult mouse organs and during embryonic development
-
L. Blavier, Y. A. DeClerck, Tissue inhibitor of metalloproteinases-2 is expressed in the interstitial matrix in adult mouse organs and during embryonic development. Mol. Biol. Cell 8, 1513-1527 (1997).
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 1513-1527
-
-
Blavier, L.1
Declerck, Y.A.2
-
25
-
-
0033135715
-
Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros
-
J. Barasch, J. Yang, J. Z. Qiao, P. Tempst, H. Erdjument-Bromage, W. Leung, J. A. Oliver, Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros. J. Clin. Invest. 103, 1299-1307 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1299-1307
-
-
Barasch, J.1
Yang, J.2
Qiao, J.Z.3
Tempst, P.4
Erdjument-Bromage, H.5
Leung, W.6
Oliver, J.A.7
-
26
-
-
0026505684
-
Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes
-
J. M. Derry, P. J. Barnard, Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes. Genomics 12, 632-638 (1992).
-
(1992)
Genomics
, vol.12
, pp. 632-638
-
-
Derry, J.M.1
Barnard, P.J.2
-
27
-
-
79960655760
-
The DNA sequence of human chromosome 22
-
I. Dunham, N. Shimizu, B. A. Roe, S. Chissoe, A. R. Hunt, J. E. Collins, R. Bruskiewich, D. M. Beare, M. Clamp, L. J. Smink, R. Ainscough, J. P. Almeida, A. Babbage, C. Bagguley, J. Bailey, K. Barlow, K. N. Bates, O. Beasley, C. P. Bird, S. Blakey, A. M. Bridgeman, D. Buck, J. Burgess, W. D. Burrill, K. P. O'Brien, The DNA sequence of human chromosome 22. Nature 402, 489-495 (1999).
-
(1999)
Nature
, vol.402
, pp. 489-495
-
-
Dunham, I.1
Shimizu, N.2
Roe, B.A.3
Chissoe, S.4
Hunt, A.R.5
Collins, J.E.6
Bruskiewich, R.7
Beare, D.M.8
Clamp, M.9
Smink, L.J.10
Ainscough, R.11
Almeida, J.P.12
Babbage, A.13
Bagguley, C.14
Bailey, J.15
Barlow, K.16
Bates, K.N.17
Beasley, O.18
Bird, C.P.19
Blakey, S.20
Bridgeman, A.M.21
Buck, D.22
Burgess, J.23
Burrill, W.D.24
O'Brien, K.P.25
more..
-
28
-
-
0345465698
-
Invertebrate tissue inhibitor of metalloproteinase: Structure and nested gene organization within the synapsin locus is conserved from Drosophila to human
-
N. Pohar, T. A. Godenschwege, E. Buchner, Invertebrate tissue inhibitor of metalloproteinase: Structure and nested gene organization within the synapsin locus is conserved from Drosophila to human. Genomics 57, 293-296 (1999).
-
(1999)
Genomics
, vol.57
, pp. 293-296
-
-
Pohar, N.1
Godenschwege, T.A.2
Buchner, E.3
-
29
-
-
0033611685
-
Synapsins as regulators of neurotransmitter release
-
S. Hilfiker, V. A. Pieribone, A. J. Czernik, H. T. Kao, G. J. Augustine, P. Greengard, Synapsins as regulators of neurotransmitter release. Philos. Trans. R. Soc. London Ser. B 354, 269-279 (1999).
-
(1999)
Philos. Trans. R. Soc. London Ser. B
, vol.354
, pp. 269-279
-
-
Hilfiker, S.1
Pieribone, V.A.2
Czernik, A.J.3
Kao, H.T.4
Augustine, G.J.5
Greengard, P.6
-
30
-
-
0034693233
-
The human tissue inhibitor of metalloproteinases (TIMP), 1 gene contains repressive elements within the promoter and intron 1
-
G. Dean, D. A. Young, D. R. Edwards, I. M. Clark, The human tissue inhibitor of metalloproteinases (TIMP)-1 gene contains repressive elements within the promoter and intron 1. J. Biol. Chem. 275, 32664-32671 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32664-32671
-
-
Dean, G.1
Young, D.A.2
Edwards, D.R.3
Clark, I.M.4
-
31
-
-
33947724072
-
Potential regulatory relationship between the nested gene DDC8 and its host gene tissue inhibitor of metalloproteinase-2
-
D. M. Jaworski, M. Beem-Miller, G. Lluri, R. Barrantes-Reynolds, Potential regulatory relationship between the nested gene DDC8 and its host gene tissue inhibitor of metalloproteinase-2. Physiol. Genomics 28, 168-178 (2007).
-
(2007)
Physiol. Genomics
, vol.28
, pp. 168-178
-
-
Jaworski, D.M.1
Beem-Miller, M.2
Lluri, G.3
Barrantes-Reynolds, R.4
-
32
-
-
0034714348
-
Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2 (Timp-2) gene alters proMMP-2 activation
-
J. J. Caterina, S. Yamada, N. C. M. Caterina, G. Longenecker, K. Holmback, J. Shi, A. E. Yermovsky, J. A. Engler, H. Birkedal-Hansen, Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2 (Timp-2) gene alters proMMP-2 activation. J. Biol. Chem. 275, 26416-26422 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26416-26422
-
-
Caterina, J.J.1
Yamada, S.2
Caterina, N.C.M.3
Longenecker, G.4
Holmback, K.5
Shi, J.6
Yermovsky, A.E.7
Engler, J.A.8
Birkedal-Hansen, H.9
-
33
-
-
0034714202
-
TIMP- 2 is required for efficient activation of proMMP-2 in vivo
-
Z. Wang, R. Juttermann, P. D. Soloway, TIMP- 2 is required for efficient activation of proMMP-2 in vivo. J. Biol. Chem. 275, 26411-26415 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26411-26415
-
-
Wang, Z.1
Juttermann, R.2
Soloway, P.D.3
-
34
-
-
34548749917
-
Tissue inhibitor of metalloproteinases- 1 promotes liver metastasis by induction of hepatocyte growth factor signaling
-
C. Kopitz, M. Gerg, O. R. Bandapalli, D. Ister, C. J. Pennington, S. Hauser, C. Flechsig, H. W. Krell, D. Antolovic, K. Brew, H. Nagase, M. Stangl, C. W. von Weyhern, B. L. Brucher, K. Brand, L. M. Coussens, D. R. Edwards, A. Kruger, Tissue inhibitor of metalloproteinases- 1 promotes liver metastasis by induction of hepatocyte growth factor signaling. Cancer Res. 67, 8615-8623 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 8615-8623
-
-
Kopitz, C.1
Gerg, M.2
Bandapalli, O.R.3
Ister, D.4
Pennington, C.J.5
Hauser, S.6
Flechsig, C.7
Krell, H.W.8
Antolovic, D.9
Brew, K.10
Nagase, H.11
Stangl, M.12
Von Weyhern, C.W.13
Brucher, B.L.14
Br, K.15
Coussens, L.M.16
Edwards, D.R.17
Kruger, A.18
-
35
-
-
16244389638
-
Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration
-
F. F. Mohammed, C. J. Pennington, Z. Kassiri, J. S. Rubin, P. D. Soloway, U. Ruther, D. R. Edwards, R. Khokha, Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology 41, 857-867 (2005).
-
(2005)
Hepatology
, vol.41
, pp. 857-867
-
-
Mohammed, F.F.1
Pennington, C.J.2
Kassiri, Z.3
Rubin, J.S.4
Soloway, P.D.5
Ruther, U.6
Edwards, D.R.7
Khokha, R.8
-
36
-
-
0033598169
-
Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1
-
D. C. Martin, J. L. Fowlkes, B. Babic, R. Khokha, Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1. J. Cell Biol. 146, 881-892 (1999).
-
(1999)
J. Cell Biol.
, vol.146
, pp. 881-892
-
-
Martin, D.C.1
Fowlkes, J.L.2
Babic, B.3
Khokha, R.4
-
37
-
-
0022382006
-
Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity
-
A. J. Docherty, A. Lyons, B. J. Smith, E. M. Wright, P. E. Stephens, T. J. Harris, G. Murphy, J. J. Reynolds, Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318, 66-69 (1985).
-
(1985)
Nature
, vol.318
, pp. 66-69
-
-
Docherty, A.J.1
Lyons, A.2
Smith, B.J.3
Wright, E.M.4
Stephens, P.E.5
Harris, T.J.6
Murphy, G.7
Reynolds, J.J.8
-
38
-
-
0021775945
-
Characterization of purified human erythroid-potentiating activity
-
J. C. Gasson, N. Bersch, D. W. Golde, Characterization of purified human erythroid-potentiating activity. Prog. Clin. Biol. Res. 184, 95-104 (1985).
-
(1985)
Prog. Clin. Biol. Res.
, vol.184
, pp. 95-104
-
-
Gasson, J.C.1
Bersch, N.2
Golde, D.W.3
-
39
-
-
0026601513
-
Tissue inhibitor of metalloproteinase-2 (TIMP-2) has erythroid- potentiating activity
-
W. G. Stetler-Stevenson, N. Bersch, D. W. Golde, Tissue inhibitor of metalloproteinase-2 (TIMP-2) has erythroid-potentiating activity. FEBS Lett. 296, 231-234 (1992).
-
(1992)
FEBS Lett
, vol.296
, pp. 231-234
-
-
Stetler-Stevenson, W.G.1
Bersch, N.2
Golde, D.W.3
-
40
-
-
18844402179
-
Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients
-
M. B. Larsen, R. W. Stephens, N. Brunner, H. J. Nielsen, L. H. Engelholm, I. J. Christensen, W. G. Stetler-Stevenson, G. Hoyer-Hansen, Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients. Scand. J. Immunol. 61, 449-460 (2005).
-
(2005)
Scand. J. Immunol.
, vol.61
, pp. 449-460
-
-
Larsen, M.B.1
Stephens, R.W.2
Brunner, N.3
Nielsen, H.J.4
Engelholm, L.H.5
Christensen, I.J.6
Stetler-Stevenson, W.G.7
Hoyer-Hansen, G.8
-
41
-
-
13544264711
-
Concentration of metalloproteinase- 2 and tissue inhibitor of metalloproteinase- 2 in the serum of patients with benign and malignant thyroid tumours treated surgically
-
Z. Pasieka, H. Stepien, W. Czyz, L. Pomorski, K. Kuzdak, Concentration of metalloproteinase- 2 and tissue inhibitor of metalloproteinase- 2 in the serum of patients with benign and malignant thyroid tumours treated surgically. Endocr. Regul. 38, 57-63 (2004).
-
(2004)
Endocr. Regul.
, vol.38
, pp. 57-63
-
-
Pasieka, Z.1
Stepien, H.2
Czyz, W.3
Pomorski, L.4
Kuzdak, K.5
-
42
-
-
0025988402
-
Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases
-
B. Bertaux, W. Hornebeck, A. Z. Eisen, L. Dubertret, Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. J. Invest. Dermatol. 97, 679-685 (1991).
-
(1991)
J. Invest. Dermatol.
, vol.97
, pp. 679-685
-
-
Bertaux, B.1
Hornebeck, W.2
Eisen, A.Z.3
Dubertret, L.4
-
43
-
-
0029035551
-
Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism
-
M. L. Corcoran, W. G. Stetler-Stevenson, Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. J. Biol. Chem. 270, 13453-13459 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13453-13459
-
-
Corcoran, M.L.1
Stetler-Stevenson, W.G.2
-
44
-
-
0028132867
-
Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP- 2)
-
T. Hayakawa, K. Yamashita, E. Ohuchi, A. Shinagawa, Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP- 2). J. Cell Sci. 107, 2373-2379 (1994).
-
(1994)
J. Cell Sci.
, vol.107
, pp. 2373-2379
-
-
Hayakawa, T.1
Yamashita, K.2
Ohuchi, E.3
Shinagawa, A.4
-
45
-
-
0026568011
-
Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum
-
T. Hayakawa, K. Yamashita, K. Tanzawa, E. Uchijima, K. Iwata, Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum. FEBS Lett. 298, 29-32 (1992).
-
(1992)
FEBS Lett
, vol.298
, pp. 29-32
-
-
Hayakawa, T.1
Yamashita, K.2
Tanzawa, K.3
Uchijima, E.4
Iwata, K.5
-
46
-
-
0027301930
-
TIMP-2, a growth-stimulatory protein from SV40-transformed human fibroblasts
-
J. A. Nemeth, C. L. Goolsby, TIMP-2, a growth-stimulatory protein from SV40-transformed human fibroblasts. Exp. Cell Res. 207, 376-382 (1993).
-
(1993)
Exp. Cell Res.
, vol.207
, pp. 376-382
-
-
Nemeth, J.A.1
Goolsby, C.L.2
-
47
-
-
0029919115
-
TIMP-2 growth-stimulatory activity: A concentration- and cell type-specific response in the presence of insulin
-
J. A. Nemeth, A. Rafe, M. Steiner, C. L. Goolsby, TIMP-2 growth-stimulatory activity: A concentration- and cell type-specific response in the presence of insulin. Exp. Cell Res. 224, 110-115 (1996).
-
(1996)
Exp. Cell Res.
, vol.224
, pp. 110-115
-
-
Nemeth, J.A.1
Rafe, A.2
Steiner, M.3
Goolsby, C.L.4
-
48
-
-
0028850519
-
Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1
-
L. Chesler, D. W. Golde, N. Bersch, M. D. Johnson, Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1. Blood 86, 4506-4515 (1995).
-
(1995)
Blood
, vol.86
, pp. 4506-4515
-
-
Chesler, L.1
Golde, D.W.2
Bersch, N.3
Johnson, M.D.4
-
49
-
-
0028898340
-
Cell surface binding of TIMP-2 and pro-MMP-2/TIMP-2 complex
-
M. R. Emmert-Buck, H. P. Emonard, M. L. Corcoran, H. C. Krutzsch, J. M. Foidart, W. G. Stetler-Stevenson, Cell surface binding of TIMP-2 and pro-MMP-2/TIMP-2 complex. FEBS Lett. 364, 28-32 (1995).
-
(1995)
FEBS Lett
, vol.364
, pp. 28-32
-
-
Emmert-Buck, M.R.1
Emonard, H.P.2
Corcoran, M.L.3
Krutzsch, H.C.4
Foidart, J.M.5
Stetler-Stevenson, W.G.6
-
50
-
-
0030605008
-
Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2)
-
K. Yamashita, M. Suzuki, H. Iwata, T. Koike, M. Hamaguchi, A. Shinagawa, T. Noguchi, T. Hayakawa, Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2). FEBS Lett. 396, 103-107 (1996).
-
(1996)
FEBS Lett
, vol.396
, pp. 103-107
-
-
Yamashita, K.1
Suzuki, M.2
Iwata, H.3
Koike, T.4
Hamaguchi, M.5
Shinagawa, A.6
Noguchi, T.7
Hayakawa, T.8
-
51
-
-
0036036810
-
Both tissue inhibitors of metalloproteinases- 1 (TIMP-1) and TIMP-2 activate Ras but through different pathways
-
T. Wang, K. Yamashita, K. Iwata, T. Hayakawa, Both tissue inhibitors of metalloproteinases- 1 (TIMP-1) and TIMP-2 activate Ras but through different pathways. Biochem. Biophys. Res. Commun. 296, 201-205 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 201-205
-
-
Wang, T.1
Yamashita, K.2
Iwata, K.3
Hayakawa, T.4
-
52
-
-
0026465338
-
Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts
-
T. T. Yang, S. P. Hawkes, Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 89, 10676-10680 (1992).
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10676-10680
-
-
Yang, T.T.1
Hawkes, S.P.2
-
53
-
-
0032407788
-
In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1
-
L. Guedez, W. G. Stetler-Stevenson, L. Wolff, J. Wang, P. Fukushima, A. Mansoor, M. Stetler-Stevenson, In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1. J. Clin. Invest. 102, 2002-2010 (1998).
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 2002-2010
-
-
Guedez, L.1
Stetler-Stevenson, W.G.2
Wolff, L.3
Wang, J.4
Fukushima, P.5
Mansoor, A.6
Stetler-Stevenson, M.7
-
54
-
-
0035869567
-
Tissue inhibitor of metalloproteinases 1 regulation of interleukin-10 in B-cell differentiation and lymphomagenesis
-
L. Guedez, A. Mansoor, B. Birkedal-Hansen, M. S. Lim, P. Fukushima, D. Venzon, W. G. Stetler-Stevenson, M. Stetler-Stevenson, Tissue inhibitor of metalloproteinases 1 regulation of interleukin-10 in B-cell differentiation and lymphomagenesis. Blood 97, 1796-1802 (2001).
-
(2001)
Blood
, vol.97
, pp. 1796-1802
-
-
Guedez, L.1
Mansoor, A.2
Birkedal-Hansen, B.3
Lim, M.S.4
Fukushima, P.5
Venzon, D.6
Stetler-Stevenson, W.G.7
Stetler-Stevenson, M.8
-
55
-
-
0035066974
-
Tissue inhibitor of metalloproteinase- 1 alters the tumorigenicity of Burkitt's lymphoma via divergent effects on tumor growth and angiogenesis
-
L. Guedez, A. J. McMarlin, D. W. Kingma, T. A. Bennett, M. Stetler-Stevenson, W. G. Stetler-Stevenson, Tissue inhibitor of metalloproteinase- 1 alters the tumorigenicity of Burkitt's lymphoma via divergent effects on tumor growth and angiogenesis. Am. J. Pathol. 158, 1207-1215 (2001).
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1207-1215
-
-
Guedez, L.1
McMarlin, A.J.2
Kingma, D.W.3
Bennett, T.A.4
Stetler-Stevenson, M.5
Stetler-Stevenson, W.G.6
-
56
-
-
0033572494
-
Tissue inhibitor of metalloproteinase-1 inhibits apoptosis of human breast epithelial cells
-
G. Li, R. Fridman, H. R. Kim, Tissue inhibitor of metalloproteinase-1 inhibits apoptosis of human breast epithelial cells. Cancer Res. 59, 6267-6275 (1999).
-
(1999)
Cancer Res
, vol.59
, pp. 6267-6275
-
-
Li, G.1
Fridman, R.2
Kim, H.R.3
-
57
-
-
0141993985
-
Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway
-
X. W. Liu, M. M. Bernardo, R. Fridman, H. R. Kim, Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway. J. Biol. Chem. 278, 40364- 40372 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40364-40372
-
-
Liu, X.W.1
Bernardo, M.M.2
Fridman, R.3
Kim, H.R.4
-
58
-
-
13444311544
-
Tissue inhibitor of metalloproteinase- 1 protects human breast epithelial cells from extrinsic cell death: A potential oncogenic activity of tissue inhibitor of metalloproteinase-1
-
X. W. Liu, M. E. Taube, K. K. Jung, Z. Dong, Y. J. Lee, S. Roshy, B. F. Sloane, R. Fridman, H. R. Kim, Tissue inhibitor of metalloproteinase- 1 protects human breast epithelial cells from extrinsic cell death: A potential oncogenic activity of tissue inhibitor of metalloproteinase-1. Cancer Res. 65, 898-906 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 898-906
-
-
Liu, X.W.1
Taube, M.E.2
Jung, K.K.3
Dong, Z.4
Lee, Y.J.5
Roshy, S.6
Sloane, B.F.7
Fridman, R.8
Kim, H.R.9
-
59
-
-
0035033889
-
Tissue inhibitor of metalloproteinase-1 prevents cytokine- mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells
-
X. Han, Y. Sun, S. Scott, D. Bleich, Tissue inhibitor of metalloproteinase-1 prevents cytokine- mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells. Diabetes 50, 1047-1055 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1047-1055
-
-
Han, X.1
Sun, Y.2
Scott, S.3
Bleich, D.4
-
60
-
-
34548399007
-
Factors released from embryonic stem cells inhibit apoptosis of H9c2 cells
-
D. K. Singla, D. E. McDonald, Factors released from embryonic stem cells inhibit apoptosis of H9c2 cells. Am. J. Physiol. Heart Circ. Physiol. 293, H1590-H1595 (2007).
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.293
-
-
Singla, D.K.1
McDonald, D.E.2
-
61
-
-
0032545643
-
TIMP-2 overexpression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis
-
P. Valente, G. Fassina, A. Melchiori, L. Masiello, M. Cilli, A. Vacca, M. Onisto, L. Santi, W. G. Stetler-Stevenson, A. Albini, TIMP-2 overexpression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int. J. Cancer 75, 246-253 (1998).
-
(1998)
Int. J. Cancer
, vol.75
, pp. 246-253
-
-
Valente, P.1
Fassina, G.2
Melchiori, A.3
Masiello, L.4
Cilli, M.5
Vacca, A.6
Onisto, M.7
Santi, L.8
Stetler-Stevenson, W.G.9
Albini, A.10
-
62
-
-
0032853461
-
Tissue inhibitor of metalloproteinase- 2 induces apoptosis in human T lymphocytes
-
M. S. Lim, L. Guedez, W. G. Stetler-Stevenson, M. Stetler-Stevenson, Tissue inhibitor of metalloproteinase- 2 induces apoptosis in human T lymphocytes. Ann. N.Y. Acad. Sci. 878, 522-523 (1999).
-
(1999)
Ann. N.Y. Acad. Sci.
, vol.878
, pp. 522-523
-
-
Lim, M.S.1
Guedez, L.2
Stetler-Stevenson, W.G.3
Stetler-Stevenson, M.4
-
63
-
-
0032521142
-
Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro: TIMP-3 promotes apoptosis
-
A. H. Baker, A. B. Zaltsman, S. J. George, A. C. Newby, Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro: TIMP-3 promotes apoptosis. J. Clin. Invest. 101, 1478-1487 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1478-1487
-
-
Baker, A.H.1
Zaltsman, A.B.2
George, S.J.3
Newby, A.C.4
-
64
-
-
0038297557
-
Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors
-
M. Ahonen, M. Poukkula, A. H. Baker, M. Kashiwagi, H. Nagase, J. E. Eriksson, V. M. Kahari, Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors. Oncogene 22, 2121-2134 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 2121-2134
-
-
Ahonen, M.1
Poukkula, M.2
Baker, A.H.3
Kashiwagi, M.4
Nagase, H.5
Eriksson, J.E.6
Kahari, V.M.7
-
65
-
-
0032974030
-
Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3
-
A. H. Baker, S. J. George, A. B. Zaltsman, G. Murphy, A. C. Newby, Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3. Br. J. Cancer 79, 1347-1355 (1999).
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1347-1355
-
-
Baker, A.H.1
George, S.J.2
Zaltsman, A.B.3
Murphy, G.4
Newby, A.C.5
-
66
-
-
4444229437
-
Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration
-
F. F. Mohammed, D. S. Smookler, S. E. M. Taylor, B. Fingleton, Z. Kassiri, O. H. Sanchez, J. L. English, L. M. Matrisian, B. Au, W. C. Yeh, R. Khokha, Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nat. Genet. 36, 969-977 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 969-977
-
-
Mohammed, F.F.1
Smookler, D.S.2
Taylor, S.E.M.3
Fingleton, B.4
Kassiri, Z.5
Sanchez, O.H.6
English, J.L.7
Matrisian, L.M.8
Au, B.9
Yeh, W.C.10
Khokha, R.11
-
67
-
-
0029810478
-
Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3
-
J. Bian, Y. Wang, M. R. Smith, H. Kim, C. Jacobs, J. Jackman, H. F. Kung, N. H. Colburn, Y. Sun, Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3. Carcinogenesis 17, 1805-1811 (1996).
-
(1996)
Carcinogenesis
, vol.17
, pp. 1805-1811
-
-
Bian, J.1
Wang, Y.2
Smith, M.R.3
Kim, H.4
Jacobs, C.5
Jackman, J.6
Kung, H.F.7
Colburn, N.H.8
Sun, Y.9
-
68
-
-
0031259566
-
TIMP-3 induces cell death by stabilizing TNF-〈 receptors on the surface of human colon carcinoma cells
-
M. R. Smith, H. Kung, S. K. Durum, N. H. Colburn, Y. Sun, TIMP-3 induces cell death by stabilizing TNF-〈 receptors on the surface of human colon carcinoma cells. Cytokine 9, 770-780 (1997).
-
(1997)
Cytokine
, vol.9
, pp. 770-780
-
-
Smith, M.R.1
Kung, H.2
Durum, S.K.3
Colburn, N.H.4
Sun, Y.5
-
69
-
-
0035866816
-
Stimulation of mammary tumorigenesis by systemic tissue inhibitor of matrix metalloproteinase 4 gene delivery
-
Y. Jiang, M. Wang, M. Y. Celiker, Y. E. Liu, Q. X. Sang, I. D. Goldberg, Y. E. Shi, Stimulation of mammary tumorigenesis by systemic tissue inhibitor of matrix metalloproteinase 4 gene delivery. Cancer Res. 61, 2365-2370 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 2365-2370
-
-
Jiang, Y.1
Wang, M.2
Celiker, M.Y.3
Liu, Y.E.4
Sang, Q.X.5
Goldberg, I.D.6
Shi, Y.E.7
-
70
-
-
0033566049
-
TIMP-1 is important for epithelial proliferation and branching morphogenesis during mouse mammary development
-
J. E. Fata, K. J. Leco, R. A. Moorehead, D. C. Martin, R. Khokha, TIMP-1 is important for epithelial proliferation and branching morphogenesis during mouse mammary development. Dev. Biol. 211, 238-254 (1999).
-
(1999)
Dev. Biol.
, vol.211
, pp. 238-254
-
-
Fata, J.E.1
Leco, K.J.2
Moorehead, R.A.3
Martin, D.C.4
Khokha, R.5
-
71
-
-
33646859892
-
TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27KIP1 protein
-
M. E. Taube, X. W. Liu, R. Fridman, H. R. Kim, TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27KIP1 protein. Oncogene 25, 3041-3048 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 3041-3048
-
-
Taube, M.E.1
Liu, X.W.2
Fridman, R.3
Kim, H.R.4
-
72
-
-
0025351278
-
Identification of an inhibitor of neovascularization from cartilage
-
M. A. Moses, J. Sudhalter, R. Langer, Identification of an inhibitor of neovascularization from cartilage. Science 248, 1408-1410 (1990).
-
(1990)
Science
, vol.248
, pp. 1408-1410
-
-
Moses, M.A.1
Sudhalter, J.2
Langer, R.3
-
73
-
-
0027383944
-
Tissue inhibitor of metalloproteinases- 2 inhibits bFGF-induced human microvascular endothelial cell proliferation
-
A. N. Murphy, E. J. Unsworth, W. G. Stetler- Stevenson, Tissue inhibitor of metalloproteinases- 2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J. Cell. Physiol. 157, 351-358 (1993).
-
(1993)
J. Cell. Physiol.
, vol.157
, pp. 351-358
-
-
Murphy, A.N.1
Unsworth, E.J.2
Stetler-Stevenson, W.G.3
-
74
-
-
84890057773
-
Tissue inhibitor of metalloproteinases-3 interacts with angiogtensin II type receptor and additively inhibits angiogensis
-
in press.
-
K. H. Kang, S. Y. Park, S. B. Rho, J. H. Lee, Tissue inhibitor of metalloproteinases-3 interacts with angiogtensin II type receptor and additively inhibits angiogensis. Cardiovasc. Res. published online, in press.
-
Cardiovasc. Res. Published Online
-
-
Kang, K.H.1
Park, S.Y.2
Rho, S.B.3
Lee, J.H.4
-
75
-
-
0037393850
-
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
-
J. H. Qi, Q. Ebrahem, N. Moore, G. Murphy, L. Claesson-Welsh, M. Bond, A. Baker, B. Anand-Apte, A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat. Med. 9, 407-415 (2003).
-
(2003)
Nat. Med.
, vol.9
, pp. 407-415
-
-
Qi, J.H.1
Ebrahem, Q.2
Moore, N.3
Murphy, G.4
Claesson-Welsh, L.5
Bond, M.6
Baker, A.7
Anand-Apte, B.8
-
76
-
-
0035913171
-
Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA
-
M. Y. Celiker, M. Wang, E. Atsidaftos, X. Liu, Y. E. Liu, Y. Jiang, E. Valderrama, I. D. Goldberg, Y. E. Shi, Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA. Oncogene 20, 4337-4343 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 4337-4343
-
-
Celiker, M.Y.1
Wang, M.2
Atsidaftos, E.3
Liu, X.4
Liu, Y.E.5
Jiang, Y.6
Valderrama, E.7
Goldberg, I.D.8
Shi, Y.E.9
-
77
-
-
0033597850
-
Biophysical and functional characterization of fulllength, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli: Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions
-
P. T. Wingfield, J. K. Sax, S. J. Stahl, J. Kaufman, I. Palmer, V. Chung, M. L. Corcoran, D. E. Kleiner, W. G. Stetler-Stevenson, Biophysical and functional characterization of fulllength, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli: Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions. J. Biol. Chem. 274, 21362-21368 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21362-21368
-
-
Wingfield, P.T.1
Sax, J.K.2
Stahl, S.J.3
Kaufman, J.4
Palmer, I.5
Chung, V.6
Corcoran, M.L.7
Kleiner, D.E.8
Stetler-Stevenson, W.G.9
-
78
-
-
0035793638
-
Tissue inhibitor of metalloproteinases- 2 (TIMP-2) suppresses TKRgrowth factor signaling independent of metalloproteinase inhibition
-
S. E. Hoegy, H. R. Oh, M. L. Corcoran, W. G. Stetler-Stevenson, Tissue inhibitor of metalloproteinases- 2 (TIMP-2) suppresses TKRgrowth factor signaling independent of metalloproteinase inhibition. J. Biol. Chem. 276, 3203-3214 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3203-3214
-
-
Hoegy, S.E.1
Oh, H.R.2
Corcoran, M.L.3
Stetler-Stevenson, W.G.4
-
79
-
-
0032544524
-
Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface
-
Y. Itoh, A. Ito, K. Iwata, K. Tanzawa, Y. Mori, H. Nagase, Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface. J. Biol. Chem. 273, 24360-24367 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24360-24367
-
-
Itoh, Y.1
Ito, A.2
Iwata, K.3
Tanzawa, K.4
Mori, Y.5
Nagase, H.6
-
80
-
-
0141790968
-
TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP
-
M. M. Bernardo, R. Fridman, TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP. Biochem. J. 374, 739-745 (2003).
-
(2003)
Biochem. J.
, vol.374
, pp. 739-745
-
-
Bernardo, M.M.1
Fridman, R.2
-
81
-
-
0345617112
-
Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase- 2 (TIMP-2): Loop 6 is a novel angiogenesis inhibitor
-
C. A. Fernandez, C. Butterfield, G. Jackson, M. A. Moses, Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase- 2 (TIMP-2): Loop 6 is a novel angiogenesis inhibitor. J. Biol. Chem. 278, 40989-40995 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40989-40995
-
-
Fernandez, C.A.1
Butterfield, C.2
Jackson, G.3
Moses, M.A.4
-
82
-
-
0042197340
-
TIMP-2 mediated inhibition of angiogenesis: An MMP-independent mechanism
-
D. W. Seo, H. Li, L. Guedez, P. T. Wingfield, T. Diaz, R. Salloum, B. Y. Wei, W. G. Stetler- Stevenson, TIMP-2 mediated inhibition of angiogenesis: An MMP-independent mechanism. Cell 114, 171-180 (2003).
-
(2003)
Cell
, vol.114
, pp. 171-180
-
-
Seo, D.W.1
Li, H.2
Guedez, L.3
Wingfield, P.T.4
Diaz, T.5
Salloum, R.6
Wei, B.Y.7
Stetler-Stevenson, W.G.8
-
83
-
-
33645646321
-
Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells
-
D. W. Seo, H. Li, C. K. Qu, Y. S. Kim, T. Diaz, B. Wei, J. W. Han, W. G. Stetler-Stevenson, Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells. J. Biol. Chem. 281, 3711-3721 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3711-3721
-
-
Seo, D.W.1
Li, H.2
Qu, C.K.3
Kim, Y.S.4
Diaz, T.5
Wei, B.6
Han, J.W.7
Stetler-Stevenson, W.G.8
-
84
-
-
10844219880
-
Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK
-
J. Oh, D. W. Seo, T. Diaz, B. Wei, Y. Ward, J. M. Ray, Y. Morioka, S. Shi, H. Kitayama, C. Takahashi, M. Noda, W. G. Stetler-Stevenson, Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK. Cancer Res. 64, 9062-9069 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 9062-9069
-
-
Oh, J.1
Seo, D.W.2
Diaz, T.3
Wei, B.4
Ward, Y.5
Ray, J.M.6
Morioka, Y.7
Shi, S.8
Kitayama, H.9
Takahashi, C.10
Noda, M.11
Stetler-Stevenson, W.G.12
-
85
-
-
34347329150
-
RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity
-
T. Muraguchi, Y. Takegami, T. Ohtsuka, S. Kitajima, E. P. Chandana, A. Omura, T. Miki, R. Takahashi, N. Matsumoto, A. Ludwig, M. Noda, C. Takahashi, RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity. Nat. Neurosci. 10, 838-845 (2007).
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 838-845
-
-
Muraguchi, T.1
Takegami, Y.2
Ohtsuka, T.3
Kitajima, S.4
Chandana, E.P.5
Omura, A.6
Miki, T.7
Takahashi, R.8
Matsumoto, N.9
Ludwig, A.10
Noda, M.11
Takahashi, C.12
-
86
-
-
33646831912
-
TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118
-
J. Oh, T. Diaz, B. Wei, H. Chang, M. Noda, W. G. Stetler-Stevenson, TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118. Oncogene 25, 4230-4234 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 4230-4234
-
-
Oh, J.1
Diaz, T.2
Wei, B.3
Chang, H.4
Noda, M.5
Stetler-Stevenson, W.G.6
-
87
-
-
38049174649
-
Tissue inhibitor of metalloproteinases- 2 binding to membrane-type 1 matrix metalloproteinases induces MAPK activation and cell growth by a non-proteolytic mechanism
-
S. D'Alessio, G. Ferrari, K. Cinnante, W. Scheerer, A. C. Galloway, D. F. Roses, D. V. Rozanov, A. G. Remacle, E.-S. Oh, S. A. Shiryaev, A. Y. Strongin, G. Pintucci, P. Mignatti, Tissue inhibitor of metalloproteinases- 2 binding to membrane-type 1 matrix metalloproteinases induces MAPK activation and cell growth by a non-proteolytic mechanism. J. Biol. Chem. 283, 87-99 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 87-99
-
-
D'Alessio, S.1
Ferrari, G.2
Cinnante, K.3
Scheerer, W.4
Galloway, A.C.5
Roses, D.F.6
Rozanov, D.V.7
Remacle, A.G.8
Oh, E.-S.9
Shiryaev, S.A.10
Strongin, A.Y.11
Pintucci, G.12
Mignatti, P.13
-
88
-
-
0031750878
-
Cell cycle-associated accumulation of tissue inhibitor of metalloproteinases-1 (TIMP-1) in the nuclei of human gingival fibroblasts
-
W. Q. Zhao, H. Li, K. Yamashita, X. K. Guo, T. Hoshino, S. Yoshida, T. Shinya, T. Hayakawa, Cell cycle-associated accumulation of tissue inhibitor of metalloproteinases-1 (TIMP-1) in the nuclei of human gingival fibroblasts. J. Cell Sci. 111, 1147-1153 (1998).
-
(1998)
J. Cell Sci.
, vol.111
, pp. 1147-1153
-
-
Zhao, W.Q.1
Li, H.2
Yamashita, K.3
Guo, X.K.4
Hoshino, T.5
Yoshida, S.6
Shinya, T.7
Hayakawa, T.8
-
89
-
-
33748371637
-
Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein
-
K. K. Jung, X. W. Liu, R. Chirco, R. Fridman, H. R. Kim, Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. EMBO J. 25, 3934-3942 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 3934-3942
-
-
Jung, K.K.1
Liu, X.W.2
Chirco, R.3
Fridman, R.4
Kim, H.R.5
-
90
-
-
0033606802
-
Characterization of integrin-tetraspanin adhesion complexes: Role of tetraspanins in integrin signaling
-
F. Berditchevski, E. Odintsova, Characterization of integrin-tetraspanin adhesion complexes: Role of tetraspanins in integrin signaling. J. Cell Biol. 146, 477-492 (1999).
-
(1999)
J. Cell Biol.
, vol.146
, pp. 477-492
-
-
Berditchevski, F.1
Odintsova, E.2
-
91
-
-
33646541350
-
Novel functions of TIMPs in cell signaling
-
R. Chirco, X. W. Liu, K. K. Jung, H. R. Kim, Novel functions of TIMPs in cell signaling. Cancer Metastasis Rev. 25, 99-113 (2006).
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 99-113
-
-
Chirco, R.1
Liu, X.W.2
Jung, K.K.3
Kim, H.R.4
-
92
-
-
0030901104
-
Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3
-
B. Anand-Apte, M. S. Pepper, E. Voest, R. Montesano, B. Olsen, G. Murphy, S. S. Apte, B. Zetter, Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3. Invest. Ophthalmol. Vis. Sci. 38, 817-823 (1997).
-
(1997)
Invest. Ophthalmol. Vis. Sci.
, vol.38
, pp. 817-823
-
-
Anand-Apte, B.1
Pepper, M.S.2
Voest, E.3
Montesano, R.4
Olsen, B.5
Murphy, G.6
Apte, S.S.7
Zetter, B.8
-
93
-
-
23044495284
-
Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies
-
O. Galm, H. Suzuki, Y. Akiyama, M. Esteller, M. V. Brock, R. Osieka, S. B. Baylin, J. G. Herman, Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies. Oncogene 24, 4799-4805 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 4799-4805
-
-
Galm, O.1
Suzuki, H.2
Akiyama, Y.3
Esteller, M.4
Brock, M.V.5
Osieka, R.6
Baylin, S.B.7
Herman, J.G.8
-
94
-
-
33748527496
-
Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer
-
F. J. Kubben, C. F. Sier, M. J. Meijer, M. van den Berg, J. J. van der Reijden, G. Griffioen, C. J. van de Velde, C. B. Lamers, H. W. Verspaget, Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer. Br. J. Cancer 95, 744-751 (2006).
-
(2006)
Br. J. Cancer
, vol.95
, pp. 744-751
-
-
Kubben, F.J.1
Sier, C.F.2
Meijer, M.J.3
Vandenberg, M.4
Vander Reijden, J.J.5
Griffioen, G.6
Van Develde, C.J.7
Lamers, C.B.8
Verspaget, H.W.9
-
95
-
-
34547728776
-
Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors
-
S. M. Pulukuri, S. Patibandla, J. Patel, N. Estes, J. S. Rao, Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors. Oncogene 26, 5229-5237 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 5229-5237
-
-
Pulukuri, S.M.1
Patibandla, S.2
Patel, J.3
Estes, N.4
Rao, J.S.5
-
96
-
-
1642498263
-
Frequent hypermethylation of 5′ flanking region of TIMP-2 gene in cervical cancer
-
T. Ivanova, S. Vinokurova, A. Petrenko, E. Eshilev, N. Solovyova, F. Kisseljov, N. Kisseljova, Frequent hypermethylation of 5′ flanking region of TIMP-2 gene in cervical cancer. Int. J. Cancer 108, 882-886 (2004).
-
(2004)
Int. J. Cancer
, vol.108
, pp. 882-886
-
-
Ivanova, T.1
Vinokurova, S.2
Petrenko, A.3
Eshilev, E.4
Solovyova, N.5
Kisseljov, F.6
Kisseljova, N.7
-
97
-
-
34249931241
-
Strong association of the tissue inhibitor of metalloproteinase- 2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans
-
E. Vairaktaris, C. Yapijakis, A. Yiannopoulos, S. Vassiliou, Z. Serefoglou, A. Vylliotis, E. Nkenke, S. Derka, E. Critselis, D. Avgoustidis, F. W. Neukam, E. Patsouris, Strong association of the tissue inhibitor of metalloproteinase- 2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans. Oncol. Rep. 17, 963-968 (2007).
-
(2007)
Oncol. Rep.
, vol.17
, pp. 963-968
-
-
Vairaktaris, E.1
Yapijakis, C.2
Yiannopoulos, A.3
Vassiliou, S.4
Serefoglou, Z.5
Vylliotis, A.6
Nkenke, E.7
Derka, S.8
Critselis, E.9
Avgoustidis, D.10
Neukam, F.W.11
Patsouris, E.12
-
98
-
-
43449106192
-
Tissue inhibitor of metalloproteinases-2 G-418C polymorphism is associated with an increased risk of gastric cancer in a Chinese Population
-
L. Yang, H.-J. Gu, H.-J. Zhu, Q.-M. Sun, R.-H. Cong, B. Zhou, N.-P. Tang, B. Wang, Tissue inhibitor of metalloproteinases-2 G-418C polymorphism is associated with an increased risk of gastric cancer in a Chinese Population. Eur. J. Surg. Oncol. 34, 636-641 (2008).
-
(2008)
Eur. J. Surg. Oncol.
, vol.34
, pp. 636-641
-
-
Yang, L.1
Gu, H.-J.2
Zhu, H.-J.3
Sun, Q.-M.4
Cong, R.-H.5
Zhou, B.6
Tang, N.-P.7
Wang, B.8
-
99
-
-
38549125513
-
The tumor microenvironment: Regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2
-
W. G. Stetler-Stevenson, The tumor microenvironment: Regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2. Cancer Metastasis Rev. 27, 57-66 (2008).
-
(2008)
Cancer Metastasis Rev.
, vol.27
, pp. 57-66
-
-
Stetler-Stevenson, W.G.1
-
100
-
-
14844284571
-
TIMP-2: An endogenous inhibitor of angiogenesis
-
W. G. Stetler-Stevenson, D. W. Seo, TIMP-2: An endogenous inhibitor of angiogenesis. Trends Mol. Med. 11, 97-103 (2005).
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 97-103
-
-
Stetler-Stevenson, W.G.1
Seo, D.W.2
-
101
-
-
19044387522
-
Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal
-
L. Perez-Martinez, D. M. Jaworski, Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal. J. Neurosci. 25, 4917-4929 (2005).
-
(2005)
J. Neurosci.
, vol.25
, pp. 4917-4929
-
-
Perez-Martinez, L.1
Jaworski, D.M.2
-
102
-
-
33745089933
-
Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals
-
D. M. Jaworski, L. Perez-Martinez, Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals. J. Neurochem. 98, 234-247 (2006).
-
(2006)
J. Neurochem.
, vol.98
, pp. 234-247
-
-
Jaworski, D.M.1
Perez-Martinez, L.2
-
103
-
-
0347627272
-
EORTC-Receptor and Biomarker Group, Association between preoperative plasma levels of tissue inhibitor of metalloproteinases 1 and rectal cancer patient survival: A validation study
-
M. Holten-Andersen, I. J. Christensen, M. Nilbert, P. O. Bendahl, H. J. Nielsen, N. Brunner, E. Fernebro, EORTC-Receptor and Biomarker Group, Association between preoperative plasma levels of tissue inhibitor of metalloproteinases 1 and rectal cancer patient survival: A validation study. Eur. J. Cancer 40, 64-72 (2004).
-
(2004)
Eur. J. Cancer
, vol.40
, pp. 64-72
-
-
Holten-Andersen, M.1
Christensen, I.J.2
Nilbert, M.3
Bendahl, P.O.4
Nielsen, H.J.5
Brunner, N.6
Fernebro, E.7
-
104
-
-
4444285320
-
Plasma TIMP-1 in patients with colorectal adenomas: A prospective study
-
M. N. Holten-Andersen, C. Fenger, H. J. Nielsen, A. S. Rasmussen, I. J. Christensen, N. Brunner, O. Kronborg, Plasma TIMP-1 in patients with colorectal adenomas: A prospective study. Eur. J. Cancer 40, 2159-2164 (2004).
-
(2004)
Eur. J. Cancer
, vol.40
, pp. 2159-2164
-
-
Holten-Andersen, M.N.1
Fenger, C.2
Nielsen, H.J.3
Rasmussen, A.S.4
Christensen, I.J.5
Brunner, N.6
Kronborg, O.7
-
105
-
-
0032963210
-
High levels of tissue inhibitor of metalloproteinase-1 predict poor outcome in patients with breast cancer
-
K. McCarthy, T. Maguire, G. McGreal, E. Mc- Dermott, N. O'Higgins, M. J. Duffy, High levels of tissue inhibitor of metalloproteinase-1 predict poor outcome in patients with breast cancer. Int. J. Cancer 84, 44-48 (1999).
-
(1999)
Int. J. Cancer
, vol.84
, pp. 44-48
-
-
McCarthy, K.1
Maguire, T.2
McGreal, G.3
Mc- Dermott, E.4
O'Higgins, N.5
Duffy, M.J.6
-
106
-
-
0036065691
-
Enhanced mRNA expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in breast carcinomas is correlated with adverse prognosis
-
L. Nakopoulou, I. Giannopoulou, K. Stefanaki, E. Panayotopoulou, I. Tsirmpa, P. Alexandrou, J. Mavrommatis, S. Katsarou, P. Davaris, Enhanced mRNA expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in breast carcinomas is correlated with adverse prognosis. J. Pathol. 197, 307-313 (2002).
-
(2002)
J. Pathol.
, vol.197
, pp. 307-313
-
-
Nakopoulou, L.1
Giannopoulou, I.2
Stefanaki, K.3
Panayotopoulou, E.4
Tsirmpa, I.5
Alexandrou, P.6
Mavrommatis, J.7
Katsarou, S.8
Davaris, P.9
-
107
-
-
0842279291
-
Tumor tissue concentrations of the proteinase inhibitors tissue inhibitor of metalloproteinases-1 (TIMP-1) and plasminogen activator inhibitor type 1 (PAI-1) are complementary in determining prognosis in primary breast cancer
-
A. S. Schrohl, I. J. Christensen, A. N. Pedersen, V. Jensen, H. Mouridsen, G. Murphy, J. A. Foekens, N. Brunner, M. N. Holten- Andersen, Tumor tissue concentrations of the proteinase inhibitors tissue inhibitor of metalloproteinases-1 (TIMP-1) and plasminogen activator inhibitor type 1 (PAI-1) are complementary in determining prognosis in primary breast cancer. Mol. Cell. Proteomics 2, 164-172 (2003).
-
(2003)
Mol. Cell. Proteomics
, vol.2
, pp. 164-172
-
-
Schrohl, A.S.1
Christensen, I.J.2
Pedersen, A.N.3
Jensen, V.4
Mouridsen, H.5
Murphy, G.6
Foekens, J.A.7
Brunner, N.8
Holten-Andersen, M.N.9
|