Deoxycytidine kinase augments ATM-mediated DNA repair and contributes to radiation resistance

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Bunimovich, Yuri L ^a,b   Nair Gill, Evan ^a   Riedinger, Mireille ^a   McCracken, Melissa N ^a   Cheng, Donghui ^b   McLaughlin, Jami ^a   Radu, Caius G ^a,b   Witte, Owen N ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DEOXYCYTIDINE; DEOXYCYTIDINE KINASE; DEOXYRIBONUCLEOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW TRANSPLANTATION; CANCER RADIOTHERAPY; CANCER RECURRENCE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA METABOLISM; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EMBRYO; ENZYME SPECIFICITY; FEMALE; FIBROBLAST; HOMOLOGOUS RECOMBINATION; IN VIVO STUDY; IONIZING RADIATION; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RADIOSENSITIVITY; T LYMPHOCYTE; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; CYTOLOGY; DNA DAMAGE; DRUG EFFECTS; GENETICS; GENOMIC INSTABILITY; HEMATOPOIESIS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RADIATION RESPONSE; SITE DIRECTED MUTAGENESIS; TUMOR CELL LINE;

ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; B-LYMPHOCYTES; CELL LINE, TUMOR; DEOXYCYTIDINE; DEOXYCYTIDINE KINASE; DEOXYRIBONUCLEOSIDES; DNA DAMAGE; DNA REPAIR; GENOMIC INSTABILITY; HEMATOPOIESIS; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBSTRATE SPECIFICITY; T-LYMPHOCYTES;

EID: 84905455193     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104125     Document Type: Article

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