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Volumn 65, Issue 12, 2003, Pages 2031-2039

Activation of deoxycytidine kinase by gamma-irradiation and inactivation by hyperosmotic shock in human lymphocytes

Author keywords

Calyculin A; Deoxycytidine kinase; DNA repair; Enzyme activation; Nucleotide metabolism; Irradiation

Indexed keywords

CALYCULIN A; DEOXYCYTIDINE KINASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN INHIBITOR; THYMIDINE;

EID: 0038730444     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00182-5     Document Type: Article
Times cited : (37)

References (41)
  • 1
    • 0029162556 scopus 로고
    • Mammalian deoxyribonucleoside kinases
    • Arner E.S., Eriksson S. Mammalian deoxyribonucleoside kinases. Pharmacol. Ther. 67:1995;155-186.
    • (1995) Pharmacol. Ther. , vol.67 , pp. 155-186
    • Arner, E.S.1    Eriksson, S.2
  • 2
    • 84907117236 scopus 로고
    • DNA synthesis and nucleoside metabolism in human tonsillar lymphocyte subpopulations
    • Staub M., Spasokukotskaja T., Benczur M., Antoni F. DNA synthesis and nucleoside metabolism in human tonsillar lymphocyte subpopulations. Acta Otolaryngol. Suppl. 454:1988;118-124.
    • (1988) Acta Otolaryngol. Suppl. , vol.454 , pp. 118-124
    • Staub, M.1    Spasokukotskaja, T.2    Benczur, M.3    Antoni, F.4
  • 3
    • 0021992778 scopus 로고
    • Induction of cellular thymidine kinase occurs at the mRNA level
    • Stuart P., Ito M., Stewart C., Conrad S.E. Induction of cellular thymidine kinase occurs at the mRNA level. Mol. Cell Biol. 5:1985;1490-1497.
    • (1985) Mol. Cell Biol. , vol.5 , pp. 1490-1497
    • Stuart, P.1    Ito, M.2    Stewart, C.3    Conrad, S.E.4
  • 4
    • 0028093655 scopus 로고
    • Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukemic patients
    • Arner E.S., Spasokoukotskaja T., Juliusson G., Liliemark J., Eriksson S. Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukemic patients. Br. J. Haematol. 87:1994;715-718.
    • (1994) Br. J. Haematol. , vol.87 , pp. 715-718
    • Arner, E.S.1    Spasokoukotskaja, T.2    Juliusson, G.3    Liliemark, J.4    Eriksson, S.5
  • 5
    • 0028214771 scopus 로고
    • New targets for pyrimidine antimetabolites for the treatment of solid tumours. 2: Deoxycytidine kinase
    • Ruiz van Haperen V.W., Peters G.J. New targets for pyrimidine antimetabolites for the treatment of solid tumours. 2: Deoxycytidine kinase. Pharm. World Sci. 16:1994;104-112.
    • (1994) Pharm. World Sci. , vol.16 , pp. 104-112
    • Ruiz van Haperen, V.W.1    Peters, G.J.2
  • 6
    • 0034994444 scopus 로고    scopus 로고
    • Nucleoside analogues: Mechanisms of drug resistance and reversal strategies
    • Galmarini C.M., Mackey J.R., Dumontet C. Nucleoside analogues: mechanisms of drug resistance and reversal strategies. Leukemia. 15:2001;875-890.
    • (2001) Leukemia , vol.15 , pp. 875-890
    • Galmarini, C.M.1    Mackey, J.R.2    Dumontet, C.3
  • 7
    • 0344973660 scopus 로고    scopus 로고
    • Activation of deoxycytidine kinase during inhibition of DNA synthesis by 2-chloro-2′-deoxyadenosine (Cladribine) in human lymphocytes
    • Sasvari-Szekely M., Spasokoukotskaja T., Szoke M., Csapo Z., Turi A., Szanto I., Eriksson S., Staub M. Activation of deoxycytidine kinase during inhibition of DNA synthesis by 2-chloro-2′-deoxyadenosine (Cladribine) in human lymphocytes. Biochem. Pharmacol. 56:1998;1175-1179.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 1175-1179
    • Sasvari-Szekely, M.1    Spasokoukotskaja, T.2    Szoke, M.3    Csapo, Z.4    Turi, A.5    Szanto, I.6    Eriksson, S.7    Staub, M.8
  • 8
    • 0035370527 scopus 로고    scopus 로고
    • Collateral sensitivity to gemcitabine (2′,2′-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines
    • Bergman A.M., Munch-Petersen B., Jensen P.B., Sehested M., Veerman G., Voorn D.A., Smid K., Pinedo H.M., Peters G.J. Collateral sensitivity to gemcitabine (2′,2′-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines. Biochem. Pharmacol. 61:2001;1401-1408.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 1401-1408
    • Bergman, A.M.1    Munch-Petersen, B.2    Jensen, P.B.3    Sehested, M.4    Veerman, G.5    Voorn, D.A.6    Smid, K.7    Pinedo, H.M.8    Peters, G.J.9
  • 9
    • 0345363057 scopus 로고    scopus 로고
    • Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity
    • Spasokoukotskaja T., Sasvari-Szekely M., Keszler G., Albertioni F., Eriksson S., Staub M. Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity. Eur. J. Cancer. 35:1999;1862-1867.
    • (1999) Eur. J. Cancer , vol.35 , pp. 1862-1867
    • Spasokoukotskaja, T.1    Sasvari-Szekely, M.2    Keszler, G.3    Albertioni, F.4    Eriksson, S.5    Staub, M.6
  • 11
    • 0029964939 scopus 로고    scopus 로고
    • Increased deoxycytidine kinase activity by etoposide in L1210 murine leukemic cells
    • Ooi K., Ohkubo T., Higashigawa M., Kawasaki H., Sakurai M. Increased deoxycytidine kinase activity by etoposide in L1210 murine leukemic cells. Biol. Pharm. Bull. 19:1996;1382-1383.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 1382-1383
    • Ooi, K.1    Ohkubo, T.2    Higashigawa, M.3    Kawasaki, H.4    Sakurai, M.5
  • 12
    • 0026703119 scopus 로고
    • Comparative effects of protein phosphatase inhibitors (okadaic acid and calyculin A) on human leukemia HL60m, HL60/ADR and K562 cells
    • Sakurada K., Zheng B., Kuo J.F. Comparative effects of protein phosphatase inhibitors (okadaic acid and calyculin A) on human leukemia HL60m, HL60/ADR and K562 cells. Biochem. Biophys. Res. Commun. 187:1992;488-492.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 488-492
    • Sakurada, K.1    Zheng, B.2    Kuo, J.F.3
  • 13
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175:1988;184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 14
    • 0023789875 scopus 로고
    • Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors
    • Spasokukotskaja T., Spyrou G., Staub M. Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors. Biochem. Biophys. Res. Commun. 155:1988;923-929.
    • (1988) Biochem. Biophys. Res. Commun. , vol.155 , pp. 923-929
    • Spasokukotskaja, T.1    Spyrou, G.2    Staub, M.3
  • 16
    • 0026452612 scopus 로고
    • Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues
    • Arner E.S., Spasokoukotskaja T., Eriksson S. Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues. Biochem. Biophys. Res. Commun. 188:1992;712-718.
    • (1992) Biochem. Biophys. Res. Commun. , vol.188 , pp. 712-718
    • Arner, E.S.1    Spasokoukotskaja, T.2    Eriksson, S.3
  • 18
    • 0028170415 scopus 로고
    • Cloning and expression of mouse deoxycytidine kinase. Pure recombinant mouse and human enzymes show differences in substrate specificity
    • Karlsson A., Johansson M., Eriksson S. Cloning and expression of mouse deoxycytidine kinase. Pure recombinant mouse and human enzymes show differences in substrate specificity. J. Biol. Chem. 269:1994;24374-24378.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24374-24378
    • Karlsson, A.1    Johansson, M.2    Eriksson, S.3
  • 20
    • 0033609834 scopus 로고    scopus 로고
    • Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase
    • Parrott L.A., Templeton D.J. Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase. J. Biol. Chem. 274:1999;24731-24736.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24731-24736
    • Parrott, L.A.1    Templeton, D.J.2
  • 21
    • 0032535490 scopus 로고    scopus 로고
    • Inactivation and dephosphorylation of protein kinase B alpha (PKB alpha) promoted by hyperosmotic stress
    • Meier R., Thelen M., Hemmings B.A. Inactivation and dephosphorylation of protein kinase B alpha (PKB alpha) promoted by hyperosmotic stress. EMBO J. 17:1998;7294-7303.
    • (1998) EMBO J. , vol.17 , pp. 7294-7303
    • Meier, R.1    Thelen, M.2    Hemmings, B.A.3
  • 22
    • 0032577491 scopus 로고    scopus 로고
    • Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2
    • Kultz D., Madhany S., Burg M.B. Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2. J. Biol. Chem. 273:1998;13645-13651.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13645-13651
    • Kultz, D.1    Madhany, S.2    Burg, M.B.3
  • 23
    • 0026601469 scopus 로고
    • Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes
    • Spasokukotskaja T., Sasvari-Szekely M., Taljanidisz J., Staub M. Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes. FEBS Lett. 297:1992;151-154.
    • (1992) FEBS Lett. , vol.297 , pp. 151-154
    • Spasokukotskaja, T.1    Sasvari-Szekely, M.2    Taljanidisz, J.3    Staub, M.4
  • 24
    • 0028952497 scopus 로고
    • Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts
    • Xu Y.Z., Huang P., Plunkett W. Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts. J. Biol. Chem. 270:1995;631-637.
    • (1995) J. Biol. Chem. , vol.270 , pp. 631-637
    • Xu, Y.Z.1    Huang, P.2    Plunkett, W.3
  • 26
    • 0027236146 scopus 로고
    • Deoxyribocytidine is salvaged not only into DNA but also into phospholipid precursors. IV. Exogenous deoxyribocytidine can be used with the same efficacy as (ribo)cytidine for lipid activation
    • Sasvari-Szekely M., Spasokukotskaja T., Staub M. Deoxyribocytidine is salvaged not only into DNA but also into phospholipid precursors. IV. Exogenous deoxyribocytidine can be used with the same efficacy as (ribo)cytidine for lipid activation. Biochem. Biophys. Res. Commun. 194:1993;966-972.
    • (1993) Biochem. Biophys. Res. Commun. , vol.194 , pp. 966-972
    • Sasvari-Szekely, M.1    Spasokukotskaja, T.2    Staub, M.3
  • 27
    • 0036134326 scopus 로고    scopus 로고
    • Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation
    • Kreder N.C., van Bree C., Peters G.J., Loves W.J., Haveman J. Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation. Oncol. Rep. 9:2002;141-144.
    • (2002) Oncol. Rep. , vol.9 , pp. 141-144
    • Kreder, N.C.1    Van Bree, C.2    Peters, G.J.3    Loves, W.J.4    Haveman, J.5
  • 28
    • 0027939874 scopus 로고
    • Enhanced expression of thymidine kinase in human cells following ionizing radiation
    • Boothman D.A., Davis T.W., Sahijdak W.M. Enhanced expression of thymidine kinase in human cells following ionizing radiation. Int. J. Radiat. Oncol. Biol. Phys. 30:1994;391-398.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.30 , pp. 391-398
    • Boothman, D.A.1    Davis, T.W.2    Sahijdak, W.M.3
  • 29
    • 85009865467 scopus 로고    scopus 로고
    • 2-Chloro-2′-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes
    • Van Den Neste E., Cardoen S., Husson B., Rosier J.F., Delacauw A., Ferrant A., Van de Berghe G., Bontemps F. 2-Chloro-2′-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes. Leukemia. 16:2002;36-43.
    • (2002) Leukemia , vol.16 , pp. 36-43
    • Van Den Neste, E.1    Cardoen, S.2    Husson, B.3    Rosier, J.F.4    Delacauw, A.5    Ferrant, A.6    Van De Berghe, G.7    Bontemps, F.8
  • 30
    • 0032799001 scopus 로고    scopus 로고
    • Radiation-induced changes in nucleotide metabolism of two colon cancer cell lines with different radiosensitivities
    • Wei S., Ageron-Blanc A., Petridis F., Beaumatin J., Bonnet S., Luccioni C. Radiation-induced changes in nucleotide metabolism of two colon cancer cell lines with different radiosensitivities. Int. J. Radiat. Biol. 75:1999;1005-1013.
    • (1999) Int. J. Radiat. Biol. , vol.75 , pp. 1005-1013
    • Wei, S.1    Ageron-Blanc, A.2    Petridis, F.3    Beaumatin, J.4    Bonnet, S.5    Luccioni, C.6
  • 31
    • 0033615641 scopus 로고    scopus 로고
    • P21-activated protein kinase gamma-PAK is activated by ionizing radiation and other DNA-damaging agents. Similarities and differences to alpha-PAK
    • Roig J., Traugh J.A. p21-activated protein kinase gamma-PAK is activated by ionizing radiation and other DNA-damaging agents. Similarities and differences to alpha-PAK. J. Biol. Chem. 274:1999;31119-31122.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31119-31122
    • Roig, J.1    Traugh, J.A.2
  • 32
    • 0027943488 scopus 로고
    • Deoxycytidine kinase is phosphorylated in vitro by protein kinase C alpha
    • Wang L.M., Kucera G.L. Deoxycytidine kinase is phosphorylated in vitro by protein kinase C alpha. Biochim. Biophys. Acta. 1224:1994;161-167.
    • (1994) Biochim. Biophys. Acta , vol.1224 , pp. 161-167
    • Wang, L.M.1    Kucera, G.L.2
  • 34
    • 0027143725 scopus 로고
    • Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth
    • Mumby M.C., Walter G. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol. Rev. 73:1993;673-699.
    • (1993) Physiol. Rev. , vol.73 , pp. 673-699
    • Mumby, M.C.1    Walter, G.2
  • 36
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens V., Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem. J. 353:2001;417-439.
    • (2001) Biochem. J. , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 37
    • 0036007421 scopus 로고    scopus 로고
    • Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K
    • Kozma S.C., Thomas G. Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K. Bioessays. 24:2002;65-71.
    • (2002) Bioessays , vol.24 , pp. 65-71
    • Kozma, S.C.1    Thomas, G.2
  • 40
    • 0027260611 scopus 로고
    • A potent inhibitor of phosphatases-1 and -2A, prevents apoptosis
    • Song Q., Lavin M.F., Calyculin A. A potent inhibitor of phosphatases-1 and -2A, prevents apoptosis. Biochem. Biophys. Res. Commun. 190:1993;47-55.
    • (1993) Biochem. Biophys. Res. Commun. , vol.190 , pp. 47-55
    • Song, Q.1    Lavin, M.F.2    Calyculin, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.