-
1
-
-
79952660821
-
Control of the embryonic stem cell state
-
Young R.A. Control of the embryonic stem cell state. Cell 2011, 144(6):940-954.
-
(2011)
Cell
, vol.144
, Issue.6
, pp. 940-954
-
-
Young, R.A.1
-
2
-
-
79953163994
-
Chromatin states in pluripotent, differentiated, and reprogrammed cells
-
Fisher C.L., Fisher A.G. Chromatin states in pluripotent, differentiated, and reprogrammed cells. Curr Opin Genet Dev 2011, 21(2):140-146.
-
(2011)
Curr Opin Genet Dev
, vol.21
, Issue.2
, pp. 140-146
-
-
Fisher, C.L.1
Fisher, A.G.2
-
3
-
-
84871699564
-
Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
-
Adelman K., Lis J.T. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat Rev Genet 2012, 13(10):720-731.
-
(2012)
Nat Rev Genet
, vol.13
, Issue.10
, pp. 720-731
-
-
Adelman, K.1
Lis, J.T.2
-
4
-
-
70249104647
-
Defining mechanisms that regulate RNA polymerase II transcription in vivo
-
Fuda N.J., Ardehali M.B., Lis J.T. Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 2009, 461(7261):186-192.
-
(2009)
Nature
, vol.461
, Issue.7261
, pp. 186-192
-
-
Fuda, N.J.1
Ardehali, M.B.2
Lis, J.T.3
-
5
-
-
33847070442
-
The role of chromatin during transcription
-
Li B., Carey M., Workman J.L. The role of chromatin during transcription. Cell 2007, 128(4):707-719.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
6
-
-
84860443136
-
Enhancers: emerging roles in cell fate specification
-
Ong C.-T., Corces V.G. Enhancers: emerging roles in cell fate specification. EMBO Rep 2012, 13(5):423-430.
-
(2012)
EMBO Rep
, vol.13
, Issue.5
, pp. 423-430
-
-
Ong, C.-T.1
Corces, V.G.2
-
7
-
-
78650304236
-
Charting histone modifications and the functional organization of mammalian genomes
-
Zhou V.W., Goren A., Bernstein B.E. Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet 2011, 12(1):7-18.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.1
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
8
-
-
80052805267
-
Histone modification: cause or cog?
-
Henikoff S., Shilatifard A. Histone modification: cause or cog?. Trends Genet 2011, 27(10):389-396.
-
(2011)
Trends Genet
, vol.27
, Issue.10
, pp. 389-396
-
-
Henikoff, S.1
Shilatifard, A.2
-
9
-
-
84875149194
-
Regulation of nucleosome dynamics by histone modifications
-
Zentner G.E., Henikoff S. Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol 2013, 20(3):259-266.
-
(2013)
Nat Struct Mol Biol
, vol.20
, Issue.3
, pp. 259-266
-
-
Zentner, G.E.1
Henikoff, S.2
-
10
-
-
57849140661
-
Divergent transcription from active promoters
-
Seila A.C., Calabrese J.M., Levine S.S., Yeo G.W., Rahl P.B., Flynn R.A., et al. Divergent transcription from active promoters. Science 2008, 322(5909):1849-1851.
-
(2008)
Science
, vol.322
, Issue.5909
, pp. 1849-1851
-
-
Seila, A.C.1
Calabrese, J.M.2
Levine, S.S.3
Yeo, G.W.4
Rahl, P.B.5
Flynn, R.A.6
-
11
-
-
84876836223
-
Modification of enhancer chromatin: what, how, and why?
-
Calo E., Wysocka J. Modification of enhancer chromatin: what, how, and why?. Mol Cell 2013, 49(5):825-837.
-
(2013)
Mol Cell
, vol.49
, Issue.5
, pp. 825-837
-
-
Calo, E.1
Wysocka, J.2
-
12
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A., Bajpai R., Swigut T., Brugmann S.A., Flynn R.A., Wysocka J. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 2011, 470(7333):279-283.
-
(2011)
Nature
, vol.470
, Issue.7333
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
13
-
-
84861529303
-
Enhancers as information integration hubs in development: lessons from genomics
-
Buecker C., Wysocka J. Enhancers as information integration hubs in development: lessons from genomics. Trends Genet 2012, 28(6):276-284.
-
(2012)
Trends Genet
, vol.28
, Issue.6
, pp. 276-284
-
-
Buecker, C.1
Wysocka, J.2
-
14
-
-
84865249952
-
Transcription factors: from enhancer binding to developmental control
-
Spitz F., Furlong E.E.M. Transcription factors: from enhancer binding to developmental control. Nat Rev Genet 2012, 13(9):613-626.
-
(2012)
Nat Rev Genet
, vol.13
, Issue.9
, pp. 613-626
-
-
Spitz, F.1
Furlong, E.E.M.2
-
15
-
-
80052000538
-
Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism
-
Voss T.C., Schiltz R.L., Sung M.-H., Yen P.M., Stamatoyannopoulos J.A., Biddie S.C., et al. Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism. Cell 2011, 146(4):544-554.
-
(2011)
Cell
, vol.146
, Issue.4
, pp. 544-554
-
-
Voss, T.C.1
Schiltz, R.L.2
Sung, M.-H.3
Yen, P.M.4
Stamatoyannopoulos, J.A.5
Biddie, S.C.6
-
16
-
-
80455144479
-
Pioneer transcription factors: establishing competence for gene expression
-
Zaret K.S., Carroll J.S. Pioneer transcription factors: establishing competence for gene expression. Genes Dev 2011, 25(21):2227-2241.
-
(2011)
Genes Dev
, vol.25
, Issue.21
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
17
-
-
84857054810
-
Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification
-
Dillon N. Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification. Bioessays 2012, 34(3):194-204.
-
(2012)
Bioessays
, vol.34
, Issue.3
, pp. 194-204
-
-
Dillon, N.1
-
18
-
-
79955795581
-
Paused RNA polymerase II as a developmental checkpoint
-
Levine M. Paused RNA polymerase II as a developmental checkpoint. Cell 2011, 145(4):502-511.
-
(2011)
Cell
, vol.145
, Issue.4
, pp. 502-511
-
-
Levine, M.1
-
19
-
-
84879260661
-
A double take on bivalent promoters
-
Voigt P., Tee W.W., Reinberg D. A double take on bivalent promoters. Genes Dev 2013, 27(12):1318-1338.
-
(2013)
Genes Dev
, vol.27
, Issue.12
, pp. 1318-1338
-
-
Voigt, P.1
Tee, W.W.2
Reinberg, D.3
-
20
-
-
84884626274
-
Chromatin sampling-an emerging perspective on targeting polycomb repressor proteins
-
Klose R.J., Cooper S., Farcas A.M., Blackledge N.P., Brockdorff N. Chromatin sampling-an emerging perspective on targeting polycomb repressor proteins. PLoS Genet 2013, 9(8):e1003717.
-
(2013)
PLoS Genet
, vol.9
, Issue.8
-
-
Klose, R.J.1
Cooper, S.2
Farcas, A.M.3
Blackledge, N.P.4
Brockdorff, N.5
-
21
-
-
61749097816
-
TGF-β superfamily signaling in embryonic development and homeostasis
-
Wu M.Y., Hill C.S. TGF-β superfamily signaling in embryonic development and homeostasis. Dev Cell 2009, 16(3):329-343.
-
(2009)
Dev Cell
, vol.16
, Issue.3
, pp. 329-343
-
-
Wu, M.Y.1
Hill, C.S.2
-
22
-
-
84866742560
-
TGFβ signalling in context
-
Massague J. TGFβ signalling in context. Nat Rev Mol Cell Biol 2012, 13(10):616-630.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.10
, pp. 616-630
-
-
Massague, J.1
-
23
-
-
36448936383
-
TGFβ-SMAD signal transduction: molecular specificity and functional flexibility
-
Schmierer B., Hill C.S. TGFβ-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 2007, 8(12):970-982.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.12
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
24
-
-
70450187617
-
The regulation of TGFβ signal transduction
-
Moustakas A., Heldin C.-H. The regulation of TGFβ signal transduction. Development 2009, 136(22):3699-3714.
-
(2009)
Development
, vol.136
, Issue.22
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.-H.2
-
25
-
-
33746435907
-
Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning
-
Mesnard D., Guzman-Ayala M., Constam D.B. Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning. Development 2006, 133(13):2497-2505.
-
(2006)
Development
, vol.133
, Issue.13
, pp. 2497-2505
-
-
Mesnard, D.1
Guzman-Ayala, M.2
Constam, D.B.3
-
26
-
-
84875136981
-
Signaling pathways during maintenance and definitive endoderm differentiation of embryonic stem cells
-
Sui L., Bouwens L., Mfopou J.K. Signaling pathways during maintenance and definitive endoderm differentiation of embryonic stem cells. Int J Dev Biol 2013, 57(1):1-12.
-
(2013)
Int J Dev Biol
, vol.57
, Issue.1
, pp. 1-12
-
-
Sui, L.1
Bouwens, L.2
Mfopou, J.K.3
-
27
-
-
70349600692
-
Activin A-induced differentiation of embryonic stem cells into endoderm and pancreatic progenitors-the influence of differentiation factors and culture conditions
-
Sulzbacher S., Schroeder I.S., Truong T.T., Wobus A.M. Activin A-induced differentiation of embryonic stem cells into endoderm and pancreatic progenitors-the influence of differentiation factors and culture conditions. Stem Cell Rev 2009, 5(2):159-173.
-
(2009)
Stem Cell Rev
, vol.5
, Issue.2
, pp. 159-173
-
-
Sulzbacher, S.1
Schroeder, I.S.2
Truong, T.T.3
Wobus, A.M.4
-
28
-
-
49749152786
-
Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires Fibroblast Growth Factor activity
-
Willems E., Leyns L. Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires Fibroblast Growth Factor activity. Differentiation 2008, 76(7):745-759.
-
(2008)
Differentiation
, vol.76
, Issue.7
, pp. 745-759
-
-
Willems, E.1
Leyns, L.2
-
29
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
Brons I.G., Smithers L.E., Trotter M.W., Rugg-Gunn P., Sun B., Chuva de Sousa Lopes S.M., et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 2007, 448(7150):191-195.
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 191-195
-
-
Brons, I.G.1
Smithers, L.E.2
Trotter, M.W.3
Rugg-Gunn, P.4
Sun, B.5
Chuva de Sousa Lopes, S.M.6
-
30
-
-
84856798558
-
Mouse pluripotent stem cells at a glance
-
Pauklin S., Pedersen R.A., Vallier L. Mouse pluripotent stem cells at a glance. J Cell Sci 2011, 124(Pt 22):3727-3732.
-
(2011)
J Cell Sci
, vol.124
, Issue.PART 22
, pp. 3727-3732
-
-
Pauklin, S.1
Pedersen, R.A.2
Vallier, L.3
-
31
-
-
77953802146
-
Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cells
-
Galvin K.E., Travis E.D., Yee D., Magnuson T., Vivian J.L. Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cells. J Biol Chem 2010, 285(26):19747-19756.
-
(2010)
J Biol Chem
, vol.285
, Issue.26
, pp. 19747-19756
-
-
Galvin, K.E.1
Travis, E.D.2
Yee, D.3
Magnuson, T.4
Vivian, J.L.5
-
32
-
-
67650096520
-
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression
-
Vallier L., Mendjan S., Brown S., Chng Z., Teo A., Smithers L.E., et al. Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. Development 2009, 136(8):1339-1349.
-
(2009)
Development
, vol.136
, Issue.8
, pp. 1339-1349
-
-
Vallier, L.1
Mendjan, S.2
Brown, S.3
Chng, Z.4
Teo, A.5
Smithers, L.E.6
-
33
-
-
84883324006
-
Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming
-
Dahle O., Kuehn M.R. Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming. Stem Cells 2013, 31(8):1488-1497.
-
(2013)
Stem Cells
, vol.31
, Issue.8
, pp. 1488-1497
-
-
Dahle, O.1
Kuehn, M.R.2
-
34
-
-
78649847411
-
Smad2 mediates Activin/Nodal signaling in mesendoderm differentiation of mouse embryonic stem cells
-
Fei T., Zhu S., Xia K., Zhang J., Li Z., Han J.D., et al. Smad2 mediates Activin/Nodal signaling in mesendoderm differentiation of mouse embryonic stem cells. Cell Res 2010, 20(12):1306-1318.
-
(2010)
Cell Res
, vol.20
, Issue.12
, pp. 1306-1318
-
-
Fei, T.1
Zhu, S.2
Xia, K.3
Zhang, J.4
Li, Z.5
Han, J.D.6
-
35
-
-
84871546531
-
TGF-β-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium
-
Galvin-Burgess K.E., Travis E.D., Pierson K.E., Vivian J.L. TGF-β-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium. Stem Cells 2013, 31(1):48-58.
-
(2013)
Stem Cells
, vol.31
, Issue.1
, pp. 48-58
-
-
Galvin-Burgess, K.E.1
Travis, E.D.2
Pierson, K.E.3
Vivian, J.L.4
-
36
-
-
84863241921
-
Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation
-
Singh A.M., Reynolds D., Cliff T., Ohtsuka S., Mattheyses A.L., Sun Y., et al. Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell 2012, 10(3):312-326.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.3
, pp. 312-326
-
-
Singh, A.M.1
Reynolds, D.2
Cliff, T.3
Ohtsuka, S.4
Mattheyses, A.L.5
Sun, Y.6
-
37
-
-
77952345331
-
The role of SMAD4 in human embryonic stem cell self-renewal and stem cell fate
-
Avery S., Zafarana G., Gokhale P.J., Andrews P.W. The role of SMAD4 in human embryonic stem cell self-renewal and stem cell fate. Stem Cells 2010, 28(5):863-873.
-
(2010)
Stem Cells
, vol.28
, Issue.5
, pp. 863-873
-
-
Avery, S.1
Zafarana, G.2
Gokhale, P.J.3
Andrews, P.W.4
-
38
-
-
84880081587
-
Smad2 is essential for maintenance of the human and mouse primed pluripotent stem cell state
-
Sakaki-Yumoto M., Liu J., Ramalho-Santos M., Yoshida N., Derynck R. Smad2 is essential for maintenance of the human and mouse primed pluripotent stem cell state. J Biol Chem 2013, 288(25):18546-18560.
-
(2013)
J Biol Chem
, vol.288
, Issue.25
, pp. 18546-18560
-
-
Sakaki-Yumoto, M.1
Liu, J.2
Ramalho-Santos, M.3
Yoshida, N.4
Derynck, R.5
-
39
-
-
39049121312
-
How the Smads regulate transcription
-
Ross S., Hill C.S. How the Smads regulate transcription. Int J Biochem Cell Biol 2008, 40(3):383-408.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, Issue.3
, pp. 383-408
-
-
Ross, S.1
Hill, C.S.2
-
40
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways
-
Alarcon C., Zaromytidou A.I., Xi Q., Gao S., Yu J., Fujisawa S., et al. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways. Cell 2009, 139(4):757-769.
-
(2009)
Cell
, vol.139
, Issue.4
, pp. 757-769
-
-
Alarcon, C.1
Zaromytidou, A.I.2
Xi, Q.3
Gao, S.4
Yu, J.5
Fujisawa, S.6
-
41
-
-
36248995245
-
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
-
Fuentealba L.C., Eivers E., Ikeda A., Hurtado C., Kuroda H., Pera E.M., et al. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 2007, 131(5):980-993.
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 980-993
-
-
Fuentealba, L.C.1
Eivers, E.2
Ikeda, A.3
Hurtado, C.4
Kuroda, H.5
Pera, E.M.6
-
42
-
-
0033106484
-
A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras
-
Kretzschmar M., Doody J., Timokhina I., Massague J. A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras. Genes Dev 1999, 13(7):804-816.
-
(1999)
Genes Dev
, vol.13
, Issue.7
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massague, J.4
-
43
-
-
3142546336
-
Cyclin-dependent kinases regulate the antiproliferative function of Smads
-
Matsuura I., Denissova N.G., Wang G., He D., Long J., Liu F. Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 2004, 430(6996):226-231.
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 226-231
-
-
Matsuura, I.1
Denissova, N.G.2
Wang, G.3
He, D.4
Long, J.5
Liu, F.6
-
44
-
-
33846688094
-
Balancing BMP signaling through integrated inputs into the Smad1 linker
-
Sapkota G., Alarcon C., Spagnoli F.M., Brivanlou A.H., Massague J. Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol Cell 2007, 25(3):441-454.
-
(2007)
Mol Cell
, vol.25
, Issue.3
, pp. 441-454
-
-
Sapkota, G.1
Alarcon, C.2
Spagnoli, F.M.3
Brivanlou, A.H.4
Massague, J.5
-
45
-
-
70350785179
-
Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-β signaling
-
Gao S., Alarcon C., Sapkota G., Rahman S., Chen P.Y., Goerner N., et al. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-β signaling. Mol Cell 2009, 36(3):457-468.
-
(2009)
Mol Cell
, vol.36
, Issue.3
, pp. 457-468
-
-
Gao, S.1
Alarcon, C.2
Sapkota, G.3
Rahman, S.4
Chen, P.Y.5
Goerner, N.6
-
46
-
-
79959640061
-
A Smad action turnover switch operated by WW domain readers of a phosphoserine code
-
Aragon E., Goerner N., Zaromytidou A.I., Xi Q., Escobedo A., Massague J., et al. A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev 2011, 25(12):1275-1288.
-
(2011)
Genes Dev
, vol.25
, Issue.12
, pp. 1275-1288
-
-
Aragon, E.1
Goerner, N.2
Zaromytidou, A.I.3
Xi, Q.4
Escobedo, A.5
Massague, J.6
-
47
-
-
84875970693
-
Anteroposterior and dorsoventral patterning are coordinated by an identical patterning clock
-
Hashiguchi M., Mullins M.C. Anteroposterior and dorsoventral patterning are coordinated by an identical patterning clock. Development 2013, 140(9):1970-1980.
-
(2013)
Development
, vol.140
, Issue.9
, pp. 1970-1980
-
-
Hashiguchi, M.1
Mullins, M.C.2
-
48
-
-
84884844190
-
The cell-cycle state of stem cells determines cell fate propensity
-
Pauklin S., Vallier L. The cell-cycle state of stem cells determines cell fate propensity. Cell 2013, 155(1):135-147.
-
(2013)
Cell
, vol.155
, Issue.1
, pp. 135-147
-
-
Pauklin, S.1
Vallier, L.2
-
49
-
-
82455210962
-
Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3
-
Tang L.Y., Yamashita M., Coussens N.P., Tang Y., Wang X., Li C., et al. Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3. EMBO J 2011, 30(23):4777-4789.
-
(2011)
EMBO J
, vol.30
, Issue.23
, pp. 4777-4789
-
-
Tang, L.Y.1
Yamashita, M.2
Coussens, N.P.3
Tang, Y.4
Wang, X.5
Li, C.6
-
50
-
-
79959891289
-
Recruitment of TIF1γ to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities
-
Agricola E., Randall R.A., Gaarenstroom T., Dupont S., Hill C.S. Recruitment of TIF1γ to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities. Mol Cell 2011, 43(1):85-96.
-
(2011)
Mol Cell
, vol.43
, Issue.1
, pp. 85-96
-
-
Agricola, E.1
Randall, R.A.2
Gaarenstroom, T.3
Dupont, S.4
Hill, C.S.5
-
51
-
-
58149093172
-
FAM/USP9x, a deubiquitinating enzyme essential for TGFβ signaling, controls Smad4 monoubiquitination
-
Dupont S., Mamidi A., Cordenonsi M., Montagner M., Zacchigna L., Adorno M., et al. FAM/USP9x, a deubiquitinating enzyme essential for TGFβ signaling, controls Smad4 monoubiquitination. Cell 2009, 136(1):123-135.
-
(2009)
Cell
, vol.136
, Issue.1
, pp. 123-135
-
-
Dupont, S.1
Mamidi, A.2
Cordenonsi, M.3
Montagner, M.4
Zacchigna, L.5
Adorno, M.6
-
52
-
-
84455167662
-
A poised chromatin platform for TGF-β access to master regulators
-
Xi Q., Wang Z., Zaromytidou A.I., Zhang X.H., Chow-Tsang L.F., Liu J.X., et al. A poised chromatin platform for TGF-β access to master regulators. Cell 2011, 147(7):1511-1524.
-
(2011)
Cell
, vol.147
, Issue.7
, pp. 1511-1524
-
-
Xi, Q.1
Wang, Z.2
Zaromytidou, A.I.3
Zhang, X.H.4
Chow-Tsang, L.F.5
Liu, J.X.6
-
53
-
-
78649294528
-
PARP-1 attenuates Smad-mediated transcription
-
Lonn P., van der Heide L.P., Dahl M., Hellman U., Heldin C.H., Moustakas A. PARP-1 attenuates Smad-mediated transcription. Mol Cell 2010, 40(4):521-532.
-
(2010)
Mol Cell
, vol.40
, Issue.4
, pp. 521-532
-
-
Lonn, P.1
van der Heide, L.P.2
Dahl, M.3
Hellman, U.4
Heldin, C.H.5
Moustakas, A.6
-
54
-
-
84859437880
-
Role of Smads in TGFβ signaling
-
Heldin C.H., Moustakas A. Role of Smads in TGFβ signaling. Cell Tissue Res 2012, 347(1):21-36.
-
(2012)
Cell Tissue Res
, vol.347
, Issue.1
, pp. 21-36
-
-
Heldin, C.H.1
Moustakas, A.2
-
55
-
-
51949114123
-
Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo
-
Miles W.O., Jaffray E., Campbell S.G., Takeda S., Bayston L.J., Basu S.P., et al. Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo. Genes Dev 2008, 22(18):2578-2590.
-
(2008)
Genes Dev
, vol.22
, Issue.18
, pp. 2578-2590
-
-
Miles, W.O.1
Jaffray, E.2
Campbell, S.G.3
Takeda, S.4
Bayston, L.J.5
Basu, S.P.6
-
56
-
-
0032483544
-
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-β signaling
-
Shi Y., Wang Y.F., Jayaraman L., Yang H., Massague J., Pavletich N.P. Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-β signaling. Cell 1998, 94(5):585-594.
-
(1998)
Cell
, vol.94
, Issue.5
, pp. 585-594
-
-
Shi, Y.1
Wang, Y.F.2
Jayaraman, L.3
Yang, H.4
Massague, J.5
Pavletich, N.P.6
-
57
-
-
0032014216
-
Human Smad3 and Smad4 are sequence-specific transcription activators
-
Zawel L., Dai J.L., Buckhaults P., Zhou S., Kinzler K.W., Vogelstein B., et al. Human Smad3 and Smad4 are sequence-specific transcription activators. Mol Cell 1998, 1(4):611-617.
-
(1998)
Mol Cell
, vol.1
, Issue.4
, pp. 611-617
-
-
Zawel, L.1
Dai, J.L.2
Buckhaults, P.3
Zhou, S.4
Kinzler, K.W.5
Vogelstein, B.6
-
58
-
-
27744461702
-
Dpp-responsive silencers are bound by a trimeric Mad-Medea complex
-
Gao S., Steffen J., Laughon A. Dpp-responsive silencers are bound by a trimeric Mad-Medea complex. J Biol Chem 2005, 280(43):36158-36164.
-
(2005)
J Biol Chem
, vol.280
, Issue.43
, pp. 36158-36164
-
-
Gao, S.1
Steffen, J.2
Laughon, A.3
-
59
-
-
77953728005
-
Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-β effectors
-
BabuRajendran N., Palasingam P., Narasimhan K., Sun W., Prabhakar S., Jauch R., et al. Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-β effectors. Nucleic Acids Res 2010, 38(10):3477-3488.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.10
, pp. 3477-3488
-
-
BabuRajendran, N.1
Palasingam, P.2
Narasimhan, K.3
Sun, W.4
Prabhakar, S.5
Jauch, R.6
-
60
-
-
4344608791
-
A simple molecular complex mediates widespread BMP-induced repression during Drosophila development
-
Pyrowolakis G., Hartmann B., Muller B., Basler K., Affolter M. A simple molecular complex mediates widespread BMP-induced repression during Drosophila development. Dev Cell 2004, 7(2):229-240.
-
(2004)
Dev Cell
, vol.7
, Issue.2
, pp. 229-240
-
-
Pyrowolakis, G.1
Hartmann, B.2
Muller, B.3
Basler, K.4
Affolter, M.5
-
61
-
-
77449104227
-
A conserved activation element in BMP signaling during Drosophila development
-
Weiss A., Charbonnier E., Ellertsdottir E., Tsirigos A., Wolf C., Schuh R., et al. A conserved activation element in BMP signaling during Drosophila development. Nat Struct Mol Biol 2010, 17(1):69-76.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.1
, pp. 69-76
-
-
Weiss, A.1
Charbonnier, E.2
Ellertsdottir, E.3
Tsirigos, A.4
Wolf, C.5
Schuh, R.6
-
62
-
-
34548049239
-
The Decapentaplegic morphogen gradient: from pattern formation to growth regulation
-
Affolter M., Basler K. The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nat Rev Genet 2007, 8(9):663-674.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.9
, pp. 663-674
-
-
Affolter, M.1
Basler, K.2
-
63
-
-
66349137029
-
Finding partners: how BMPs select their targets
-
Blitz I.L., Cho K.W. Finding partners: how BMPs select their targets. Dev Dyn 2009, 238(6):1321-1331.
-
(2009)
Dev Dyn
, vol.238
, Issue.6
, pp. 1321-1331
-
-
Blitz, I.L.1
Cho, K.W.2
-
64
-
-
84866274786
-
Bmp indicator mice reveal dynamic regulation of transcriptional response
-
Javier A.L., Doan L.T., Luong M., Reyes de Mochel N.S., Sun A., Monuki E.S., et al. Bmp indicator mice reveal dynamic regulation of transcriptional response. PLoS ONE 2012, 7(9):e42566.
-
(2012)
PLoS ONE
, vol.7
, Issue.9
-
-
Javier, A.L.1
Doan, L.T.2
Luong, M.3
Reyes de Mochel, N.S.4
Sun, A.5
Monuki, E.S.6
-
65
-
-
33751050017
-
Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism
-
Yao L.C., Blitz I.L., Peiffer D.A., Phin S., Wang Y., Ogata S., et al. Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism. Development 2006, 133(20):4025-4034.
-
(2006)
Development
, vol.133
, Issue.20
, pp. 4025-4034
-
-
Yao, L.C.1
Blitz, I.L.2
Peiffer, D.A.3
Phin, S.4
Wang, Y.5
Ogata, S.6
-
66
-
-
0029802485
-
A transcriptional partner for MAD proteins in TGF-β signalling
-
Chen X., Rubock M.J., Whitman M. A transcriptional partner for MAD proteins in TGF-β signalling. Nature 1996, 383(6602):691-696.
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 691-696
-
-
Chen, X.1
Rubock, M.J.2
Whitman, M.3
-
67
-
-
0030961168
-
Smad4 and FAST-1 in the assembly of activin-responsive factor
-
Chen X., Weisberg E., Fridmacher V., Watanabe M., Naco G., Whitman M. Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature 1997, 389(6646):85-89.
-
(1997)
Nature
, vol.389
, Issue.6646
, pp. 85-89
-
-
Chen, X.1
Weisberg, E.2
Fridmacher, V.3
Watanabe, M.4
Naco, G.5
Whitman, M.6
-
68
-
-
42049092376
-
Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development
-
Silvestri C., Narimatsu M., von Both I., Liu Y., Tan N.B., Izzi L., et al. Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development. Dev Cell 2008, 14(3):411-423.
-
(2008)
Dev Cell
, vol.14
, Issue.3
, pp. 411-423
-
-
Silvestri, C.1
Narimatsu, M.2
von Both, I.3
Liu, Y.4
Tan, N.B.5
Izzi, L.6
-
69
-
-
84873495850
-
Integration of nodal and BMP signals in the heart requires FoxH1 to create left-right differences in cell migration rates that direct cardiac asymmetry
-
Lenhart K.F., Holtzman N.G., Williams J.R., Burdine R.D. Integration of nodal and BMP signals in the heart requires FoxH1 to create left-right differences in cell migration rates that direct cardiac asymmetry. PLoS Genet 2013, 9(1):e1003109.
-
(2013)
PLoS Genet
, vol.9
, Issue.1
-
-
Lenhart, K.F.1
Holtzman, N.G.2
Williams, J.R.3
Burdine, R.D.4
-
70
-
-
80051520491
-
HEB and E2A function as SMAD/FOXH1 cofactors
-
Yoon S.J., Wills A.E., Chuong E., Gupta R., Baker J.C. HEB and E2A function as SMAD/FOXH1 cofactors. Genes Dev 2011, 25(15):1654-1661.
-
(2011)
Genes Dev
, vol.25
, Issue.15
, pp. 1654-1661
-
-
Yoon, S.J.1
Wills, A.E.2
Chuong, E.3
Gupta, R.4
Baker, J.C.5
-
71
-
-
0034007925
-
Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif
-
Germain S., Howell M., Esslemont G.M., Hill C.S. Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif. Genes Dev 2000, 14(4):435-451.
-
(2000)
Genes Dev
, vol.14
, Issue.4
, pp. 435-451
-
-
Germain, S.1
Howell, M.2
Esslemont, G.M.3
Hill, C.S.4
-
72
-
-
0037080983
-
Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif
-
Randall R.A., Germain S., Inman G.J., Bates P.A., Hill C.S. Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif. EMBO J 2002, 21(1-2):145-156.
-
(2002)
EMBO J
, vol.21
, Issue.1-2
, pp. 145-156
-
-
Randall, R.A.1
Germain, S.2
Inman, G.J.3
Bates, P.A.4
Hill, C.S.5
-
73
-
-
0348013150
-
Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction
-
Kunwar P.S., Zimmerman S., Bennett J.T., Chen Y., Whitman M., Schier A.F. Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development 2003, 130(23):5589-5599.
-
(2003)
Development
, vol.130
, Issue.23
, pp. 5589-5599
-
-
Kunwar, P.S.1
Zimmerman, S.2
Bennett, J.T.3
Chen, Y.4
Whitman, M.5
Schier, A.F.6
-
74
-
-
33749344476
-
Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription
-
Ross S., Cheung E., Petrakis T.G., Howell M., Kraus W.L., Hill C.S. Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription. EMBO J 2006, 25(19):4490-4502.
-
(2006)
EMBO J
, vol.25
, Issue.19
, pp. 4490-4502
-
-
Ross, S.1
Cheung, E.2
Petrakis, T.G.3
Howell, M.4
Kraus, W.L.5
Hill, C.S.6
-
75
-
-
59349117376
-
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
-
Guzman-Ayala M., Lee K.L., Mavrakis K.J., Goggolidou P., Norris D.P., Episkopou V. Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells. PLoS ONE 2009, 4(1):e4268.
-
(2009)
PLoS ONE
, vol.4
, Issue.1
-
-
Guzman-Ayala, M.1
Lee, K.L.2
Mavrakis, K.J.3
Goggolidou, P.4
Norris, D.P.5
Episkopou, V.6
-
76
-
-
79959814756
-
Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions
-
Lee K.L., Lim S.K., Orlov Y.L., Yit le Y., Yang H., Ang L.T., et al. Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions. PLoS Genet 2011, 7(6):e1002130.
-
(2011)
PLoS Genet
, vol.7
, Issue.6
-
-
Lee, K.L.1
Lim, S.K.2
Orlov, Y.L.3
Yit le, Y.4
Yang, H.5
Ang, L.T.6
-
77
-
-
79960888524
-
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors
-
Brown S., Teo A., Pauklin S., Hannan N., Cho C.H.H., Lim B., et al. Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors. Stem Cells 2011, 29(8):1176-1185.
-
(2011)
Stem Cells
, vol.29
, Issue.8
, pp. 1176-1185
-
-
Brown, S.1
Teo, A.2
Pauklin, S.3
Hannan, N.4
Cho, C.H.H.5
Lim, B.6
-
78
-
-
74949142886
-
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination
-
Fei T., Xia K., Li Z., Zhou B., Zhu S., Chen H., et al. Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination. Genome Res 2010, 20(1):36-44.
-
(2010)
Genome Res
, vol.20
, Issue.1
, pp. 36-44
-
-
Fei, T.1
Xia, K.2
Li, Z.3
Zhou, B.4
Zhu, S.5
Chen, H.6
-
79
-
-
71049163832
-
Promoter-wide analysis of Smad4 binding sites in human epithelial cells
-
Koinuma D., Tsutsumi S., Kamimura N., Imamura T., Aburatani H., Miyazono K. Promoter-wide analysis of Smad4 binding sites in human epithelial cells. Cancer Sci 2009, 100(11):2133-2142.
-
(2009)
Cancer Sci
, vol.100
, Issue.11
, pp. 2133-2142
-
-
Koinuma, D.1
Tsutsumi, S.2
Kamimura, N.3
Imamura, T.4
Aburatani, H.5
Miyazono, K.6
-
80
-
-
58149468095
-
Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor β signaling
-
Koinuma D., Tsutsumi S., Kamimura N., Taniguchi H., Miyazawa K., Sunamura M., et al. Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor β signaling. Mol Cell Biol 2009, 29(1):172-186.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.1
, pp. 172-186
-
-
Koinuma, D.1
Tsutsumi, S.2
Kamimura, N.3
Taniguchi, H.4
Miyazawa, K.5
Sunamura, M.6
-
81
-
-
80051526119
-
Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas
-
Liu Z., Lin X., Cai Z., Zhang Z., Han C., Jia S., et al. Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. J Biol Chem 2011, 286(32):28520-28532.
-
(2011)
J Biol Chem
, vol.286
, Issue.32
, pp. 28520-28532
-
-
Liu, Z.1
Lin, X.2
Cai, Z.3
Zhang, Z.4
Han, C.5
Jia, S.6
-
82
-
-
80051925342
-
Cell type-specific target selection by combinatorial binding of Smad2/3 proteins and hepatocyte nuclear factor 4 in HepG2 cells
-
Mizutani A., Koinuma D., Tsutsumi S., Kamimura N., Morikawa M., Suzuki H.I., et al. Cell type-specific target selection by combinatorial binding of Smad2/3 proteins and hepatocyte nuclear factor 4 in HepG2 cells. J Biol Chem 2011, 286(34):29848-29860.
-
(2011)
J Biol Chem
, vol.286
, Issue.34
, pp. 29848-29860
-
-
Mizutani, A.1
Koinuma, D.2
Tsutsumi, S.3
Kamimura, N.4
Morikawa, M.5
Suzuki, H.I.6
-
83
-
-
80455178772
-
ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif
-
Morikawa M., Koinuma D., Tsutsumi S., Vasilaki E., Kanki Y., Heldin C.H., et al. ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif. Nucleic Acids Res 2011, 39(20):8712-8727.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.20
, pp. 8712-8727
-
-
Morikawa, M.1
Koinuma, D.2
Tsutsumi, S.3
Vasilaki, E.4
Kanki, Y.5
Heldin, C.H.6
-
84
-
-
80155137594
-
Master transcription factors determine cell-type-specific responses to TGF-β signaling
-
Mullen A.C., Orlando D.A., Newman J.J., Loven J., Kumar R.M., Bilodeau S., et al. Master transcription factors determine cell-type-specific responses to TGF-β signaling. Cell 2011, 147(3):565-576.
-
(2011)
Cell
, vol.147
, Issue.3
, pp. 565-576
-
-
Mullen, A.C.1
Orlando, D.A.2
Newman, J.J.3
Loven, J.4
Kumar, R.M.5
Bilodeau, S.6
-
85
-
-
68949205094
-
An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules
-
Qin H., Chan M.W.Y., Liyanarachchi S., Balch C., Potter D., Souriraj I.J., et al. An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules. BMC Syst Biol 2009, 3:73.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 73
-
-
Qin, H.1
Chan, M.W.Y.2
Liyanarachchi, S.3
Balch, C.4
Potter, D.5
Souriraj, I.J.6
-
86
-
-
80155123782
-
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration
-
Trompouki E., Bowman T.V., Lawton L.N., Fan Z.P., Wu D.C., DiBiase A., et al. Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell 2011, 147(3):577-589.
-
(2011)
Cell
, vol.147
, Issue.3
, pp. 577-589
-
-
Trompouki, E.1
Bowman, T.V.2
Lawton, L.N.3
Fan, Z.P.4
Wu, D.C.5
DiBiase, A.6
-
87
-
-
0038324070
-
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
-
Postigo A.A., Depp J.L., Taylor J.J., Kroll K.L. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J 2003, 22(10):2453-2462.
-
(2003)
EMBO J
, vol.22
, Issue.10
, pp. 2453-2462
-
-
Postigo, A.A.1
Depp, J.L.2
Taylor, J.J.3
Kroll, K.L.4
-
88
-
-
0038324071
-
Opposing functions of ZEB proteins in the regulation of the TGFβ/BMP signaling pathway
-
Postigo A.A. Opposing functions of ZEB proteins in the regulation of the TGFβ/BMP signaling pathway. EMBO J 2003, 22(10):2443-2452.
-
(2003)
EMBO J
, vol.22
, Issue.10
, pp. 2443-2452
-
-
Postigo, A.A.1
-
89
-
-
73049085665
-
SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells
-
Chng Z., Teo A., Pedersen R.A., Vallier L. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells. Stem Cell 2010, 6(1):59-70.
-
(2010)
Stem Cell
, vol.6
, Issue.1
, pp. 59-70
-
-
Chng, Z.1
Teo, A.2
Pedersen, R.A.3
Vallier, L.4
-
90
-
-
0842281496
-
Ski and SnoN: negative regulators of TGF-β signaling
-
Luo K. Ski and SnoN: negative regulators of TGF-β signaling. Curr Opin Genet Dev 2004, 14(1):65-70.
-
(2004)
Curr Opin Genet Dev
, vol.14
, Issue.1
, pp. 65-70
-
-
Luo, K.1
-
91
-
-
34548238145
-
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation
-
Levy L., Howell M., Das D., Harkin S., Episkopou V., Hill C.S. Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation. Mol Cell Biol 2007, 27(17):6068-6083.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.17
, pp. 6068-6083
-
-
Levy, L.1
Howell, M.2
Das, D.3
Harkin, S.4
Episkopou, V.5
Hill, C.S.6
-
92
-
-
58149239731
-
Ski and SnoN, potent negative regulators of TGF-β signaling
-
Deheuninck J., Luo K. Ski and SnoN, potent negative regulators of TGF-β signaling. Cell Res 2009, 19(1):47-57.
-
(2009)
Cell Res
, vol.19
, Issue.1
, pp. 47-57
-
-
Deheuninck, J.1
Luo, K.2
-
93
-
-
44849143723
-
Transforming growth factor-β suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation
-
Le Scolan E., Zhu Q., Wang L., Bandyopadhyay A., Javelaud D., Mauviel A., et al. Transforming growth factor-β suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation. Cancer Res 2008, 68(9):3277-3285.
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3277-3285
-
-
Le Scolan, E.1
Zhu, Q.2
Wang, L.3
Bandyopadhyay, A.4
Javelaud, D.5
Mauviel, A.6
-
94
-
-
84869166825
-
The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells
-
Tsuneyoshi N., Tan E.K., Sadasivam A., Poobalan Y., Sumi T., Nakatsuji N., et al. The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells. Genes Dev 2012, 26(22):2471-2476.
-
(2012)
Genes Dev
, vol.26
, Issue.22
, pp. 2471-2476
-
-
Tsuneyoshi, N.1
Tan, E.K.2
Sadasivam, A.3
Poobalan, Y.4
Sumi, T.5
Nakatsuji, N.6
-
95
-
-
84862764922
-
TGF-β control of stem cell differentiation genes
-
Massague J., Xi Q. TGF-β control of stem cell differentiation genes. FEBS Lett 2012, 586(14):1953-1958.
-
(2012)
FEBS Lett
, vol.586
, Issue.14
, pp. 1953-1958
-
-
Massague, J.1
Xi, Q.2
-
96
-
-
0038369998
-
A self-enabling TGFβ response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells
-
Kang Y., Chen C.R., Massague J. A self-enabling TGFβ response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Mol Cell 2003, 11(4):915-926.
-
(2003)
Mol Cell
, vol.11
, Issue.4
, pp. 915-926
-
-
Kang, Y.1
Chen, C.R.2
Massague, J.3
-
97
-
-
43249102851
-
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
-
Cloos P.A.C., Christensen J., Agger K., Helin K. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev 2008, 22(9):1115-1140.
-
(2008)
Genes Dev
, vol.22
, Issue.9
, pp. 1115-1140
-
-
Cloos, P.A.C.1
Christensen, J.2
Agger, K.3
Helin, K.4
-
98
-
-
80051537445
-
Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs
-
Kim S.W., Yoon S.J., Chuong E., Oyolu C., Wills A.E., Gupta R., et al. Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs. Dev Biol 2011, 357(2):492-504.
-
(2011)
Dev Biol
, vol.357
, Issue.2
, pp. 492-504
-
-
Kim, S.W.1
Yoon, S.J.2
Chuong, E.3
Oyolu, C.4
Wills, A.E.5
Gupta, R.6
-
99
-
-
77956634439
-
Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes
-
Dahle O., Kumar A., Kuehn M.R. Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes. Sci Signal 2010, 3(127):ra48.
-
(2010)
Sci Signal
, vol.3
, Issue.127
-
-
Dahle, O.1
Kumar, A.2
Kuehn, M.R.3
-
100
-
-
84866788126
-
Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program
-
Estaras C., Akizu N., Garcia A., Beltran S., de la Cruz X., Martinez-Balbas M.A. Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program. Development 2012, 139(15):2681-2691.
-
(2012)
Development
, vol.139
, Issue.15
, pp. 2681-2691
-
-
Estaras, C.1
Akizu, N.2
Garcia, A.3
Beltran, S.4
de la Cruz, X.5
Martinez-Balbas, M.A.6
-
101
-
-
77956213871
-
H3K27me3 regulates BMP activity in developing spinal cord
-
Akizu N., Estaras C., Guerrero L., Marti E., Martinez-Balbas M.A. H3K27me3 regulates BMP activity in developing spinal cord. Development 2010, 137(17):2915-2925.
-
(2010)
Development
, vol.137
, Issue.17
, pp. 2915-2925
-
-
Akizu, N.1
Estaras, C.2
Guerrero, L.3
Marti, E.4
Martinez-Balbas, M.A.5
-
102
-
-
84880055491
-
Signal integration in TGF-β, WNT, and Hippo pathways
-
Attisano L., Wrana J.L. Signal integration in TGF-β, WNT, and Hippo pathways. F1000Prime Rep 2013, 5:17.
-
(2013)
F1000Prime Rep
, vol.5
, pp. 17
-
-
Attisano, L.1
Wrana, J.L.2
-
103
-
-
1542569747
-
Smad4 and β-catenin co-activators functionally interact with lymphoid-enhancing factor to regulate graded expression of Msx2
-
Hussein S.M., Duff E.K., Sirard C. Smad4 and β-catenin co-activators functionally interact with lymphoid-enhancing factor to regulate graded expression of Msx2. J Biol Chem 2003, 278(49):48805-48814.
-
(2003)
J Biol Chem
, vol.278
, Issue.49
, pp. 48805-48814
-
-
Hussein, S.M.1
Duff, E.K.2
Sirard, C.3
-
104
-
-
46049087598
-
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
-
Varelas X., Sakuma R., Samavarchi-Tehrani P., Peerani R., Rao B.M., Dembowy J., et al. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol 2008, 10(7):837-848.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.7
, pp. 837-848
-
-
Varelas, X.1
Sakuma, R.2
Samavarchi-Tehrani, P.3
Peerani, R.4
Rao, B.M.5
Dembowy, J.6
-
105
-
-
0032528236
-
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation
-
Feng X.H., Zhang Y., Wu R.Y., Derynck R. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation. Genes Dev 1998, 12(14):2153-2163.
-
(1998)
Genes Dev
, vol.12
, Issue.14
, pp. 2153-2163
-
-
Feng, X.H.1
Zhang, Y.2
Wu, R.Y.3
Derynck, R.4
-
106
-
-
0032527756
-
TGF-β-stimulated cooperation of smad proteins with the coactivators CBP/p300
-
Janknecht R., Wells N.J., Hunter T. TGF-β-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Dev 1998, 12(14):2114-2119.
-
(1998)
Genes Dev
, vol.12
, Issue.14
, pp. 2114-2119
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
107
-
-
0037043739
-
A component of the ARC/Mediator complex required for TGF β/Nodal signalling
-
Kato Y., Habas R., Katsuyama Y., Naar A.M., He X. A component of the ARC/Mediator complex required for TGF β/Nodal signalling. Nature 2002, 418(6898):641-646.
-
(2002)
Nature
, vol.418
, Issue.6898
, pp. 641-646
-
-
Kato, Y.1
Habas, R.2
Katsuyama, Y.3
Naar, A.M.4
He, X.5
-
108
-
-
38149019302
-
Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor β transcriptional program
-
Xi Q., He W., Zhang X.H., Le H.V., Massague J. Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor β transcriptional program. J Biol Chem 2008, 283(2):1146-1155.
-
(2008)
J Biol Chem
, vol.283
, Issue.2
, pp. 1146-1155
-
-
Xi, Q.1
He, W.2
Zhang, X.H.3
Le, H.V.4
Massague, J.5
-
109
-
-
65249173999
-
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
-
Ho L., Jothi R., Ronan J.L., Cui K., Zhao K., Crabtree G.R. An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci USA 2009, 106(13):5187-5191.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.13
, pp. 5187-5191
-
-
Ho, L.1
Jothi, R.2
Ronan, J.L.3
Cui, K.4
Zhao, K.5
Crabtree, G.R.6
-
110
-
-
65249180173
-
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
-
Ho L., Ronan J.L., Wu J., Staahl B.T., Chen L., Kuo A., et al. An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci USA 2009, 106(13):5181-5186.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.13
, pp. 5181-5186
-
-
Ho, L.1
Ronan, J.L.2
Wu, J.3
Staahl, B.T.4
Chen, L.5
Kuo, A.6
-
111
-
-
79961002967
-
EsBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
-
Ho L., Miller E.L., Ronan J.L., Ho W.Q., Jothi R., Crabtree G.R. esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nat Cell Biol 2011, 13(8):903-913.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.8
, pp. 903-913
-
-
Ho, L.1
Miller, E.L.2
Ronan, J.L.3
Ho, W.Q.4
Jothi, R.5
Crabtree, G.R.6
-
112
-
-
55449104935
-
Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells
-
Landry J., Sharov A.A., Piao Y., Sharova L.V., Xiao H., Southon E., et al. Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. PLoS Genet 2008, 4(10):e1000241.
-
(2008)
PLoS Genet
, vol.4
, Issue.10
-
-
Landry, J.1
Sharov, A.A.2
Piao, Y.3
Sharova, L.V.4
Xiao, H.5
Southon, E.6
-
113
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen X., Xu H., Yuan P., Fang F., Huss M., Vega V.B., et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008, 133(6):1106-1117.
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
-
114
-
-
84888038427
-
Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition
-
Lee M.T., Bonneau A.R., Takacs C.M., Bazzini A.A., Divito K.R., Fleming E.S., et al. Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition. Nature 2013, 503(7476):360-364.
-
(2013)
Nature
, vol.503
, Issue.7476
, pp. 360-364
-
-
Lee, M.T.1
Bonneau, A.R.2
Takacs, C.M.3
Bazzini, A.A.4
Divito, K.R.5
Fleming, E.S.6
-
115
-
-
84883134422
-
Pou5f1 transcription factor controls zygotic gene activation in vertebrates
-
Leichsenring M., Maes J., Mossner R., Driever W., Onichtchouk D. Pou5f1 transcription factor controls zygotic gene activation in vertebrates. Science 2013, 341(6149):1005-1009.
-
(2013)
Science
, vol.341
, Issue.6149
, pp. 1005-1009
-
-
Leichsenring, M.1
Maes, J.2
Mossner, R.3
Driever, W.4
Onichtchouk, D.5
-
116
-
-
0035890328
-
TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
-
Liu D., Black B.L., Derynck R. TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev 2001, 15(22):2950-2966.
-
(2001)
Genes Dev
, vol.15
, Issue.22
, pp. 2950-2966
-
-
Liu, D.1
Black, B.L.2
Derynck, R.3
-
117
-
-
79551592864
-
Pluripotency factors regulate definitive endoderm specification through eomesodermin
-
Teo A.K.K., Arnold S.J., Trotter M.W.B., Brown S., Ang L.T., Chng Z., et al. Pluripotency factors regulate definitive endoderm specification through eomesodermin. Genes Dev 2011, 25(3):238-250.
-
(2011)
Genes Dev
, vol.25
, Issue.3
, pp. 238-250
-
-
Teo, A.K.K.1
Arnold, S.J.2
Trotter, M.W.B.3
Brown, S.4
Ang, L.T.5
Chng, Z.6
-
118
-
-
84876928036
-
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response
-
Ding N., Yu R.T., Subramaniam N., Sherman M.H., Wilson C., Rao R., et al. A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. Cell 2013, 153(3):601-613.
-
(2013)
Cell
, vol.153
, Issue.3
, pp. 601-613
-
-
Ding, N.1
Yu, R.T.2
Subramaniam, N.3
Sherman, M.H.4
Wilson, C.5
Rao, R.6
-
119
-
-
72849107786
-
Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells
-
Vallier L., Touboul T., Brown S., Cho C., Bilican B., Alexander M., et al. Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells. Stem Cells 2009, 27(11):2655-2666.
-
(2009)
Stem Cells
, vol.27
, Issue.11
, pp. 2655-2666
-
-
Vallier, L.1
Touboul, T.2
Brown, S.3
Cho, C.4
Bilican, B.5
Alexander, M.6
-
120
-
-
33748075143
-
A FoxO-Smad synexpression group in human keratinocytes
-
Gomis R.R., Alarcon C., He W., Wang Q., Seoane J., Lash A., et al. A FoxO-Smad synexpression group in human keratinocytes. Proc Natl Acad Sci U S A 2006, 103(34):12747-12752.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.34
, pp. 12747-12752
-
-
Gomis, R.R.1
Alarcon, C.2
He, W.3
Wang, Q.4
Seoane, J.5
Lash, A.6
-
121
-
-
56549112482
-
An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-β signalling
-
Ikushima H., Komuro A., Isogaya K., Shinozaki M., Hellman U., Miyazawa K., et al. An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-β signalling. EMBO J 2008, 27(22):2955-2965.
-
(2008)
EMBO J
, vol.27
, Issue.22
, pp. 2955-2965
-
-
Ikushima, H.1
Komuro, A.2
Isogaya, K.3
Shinozaki, M.4
Hellman, U.5
Miyazawa, K.6
|