Smad2 Is essential for maintenance of the human and mouse primed pluripotent stem cell state

Journal of Biological Chemistry

Volumn 288, Issue 25, 2013, Pages 18546-18560

  Sakaki Yumoto, Masayo ^a,b   Liu, Jianming ^a,b   Ramalho Santos, Miguel ^a,c   Yoshida, Nobuaki ^a   Derynck, Rik ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Cell and Tissue Biology ^*  (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PLURIPOTENCY; PLURIPOTENT STEM CELLS;

STEM CELLS;

MAINTENANCE;

ACTIVIN; BONE MORPHOGENETIC PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR NANOG; TRANSFORMING GROWTH FACTOR BETA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO (ANATOMY); EMBRYONIC STEM CELL; EPIBLAST STEM CELL; GERM CELL; HUMAN; HUMAN CELL; MESODERM; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; STEM CELL; TROPHECTODERM;

BONE MORPHOGENETIC PROTEIN (BMP); CELL DIFFERENTIATION; NANOG; PLURIPOTENCY; SMAD TRANSCRIPTION FACTOR; STEM CELLS; TRANSFORMING GROWTH FACTOR Β (TGFΒ);

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; GERM LAYERS; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOBLOTTING; MICE; MICE, 129 STRAIN; MICROSCOPY, FLUORESCENCE; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 84880081587     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.446591     Document Type: Article

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