Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

EMBO Journal

Volumn 30, Issue 23, 2011, Pages 4777-4789

  Tang, Liu Ya ^a   Yamashita, Motozo ^a,d   Coussens, Nathan P ^a   Tang, Yi ^a   Wang, Xiangchun ^a   Li, Cuiling ^b   Deng, Chu Xia ^b   Cheng, Steven Y ^a,c   Zhang, Ying E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NANJING MEDICAL UNIVERSITY   (China)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Smad3; Smurf2; TGF ; Ubiquitination

Indexed keywords

CELL PROTEIN; LYSINE; SMAD UBIQUITINATION REGULATORY FACTOR; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; EMBRYO; FIBROBLAST; GENE DISRUPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UBIQUITINATION;

ANIMALS; BLOTTING, WESTERN; FIBROBLASTS; MICE; MODELS, BIOLOGICAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

MUS;

EID: 82455210962     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.393     Document Type: Article

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