-
1
-
-
33845906339
-
Inhaling medicines: Delivering drugs to the body through the lungs
-
Patton JS, Byron PR (2007) Inhaling medicines: delivering drugs to the body through the lungs. Nat Rev Drug Discov 6:67-74
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 67-74
-
-
Patton, J.S.1
Byron, P.R.2
-
2
-
-
84881377924
-
Pulmonary drug delivery: From generating aerosols to overcoming biological barriers -therapeutic possibilities and technological challenges
-
Ruge CA, Kirch J, Lehr CM (2013) Pulmonary drug delivery: from generating aerosols to overcoming biological barriers -therapeutic possibilities and technological challenges. Lancet Respir Med 1:402-413
-
(2013)
Lancet Respir Med
, vol.1
, pp. 402-413
-
-
Ruge, C.A.1
Kirch, J.2
Lehr, C.M.3
-
5
-
-
78650225640
-
The particle has landed -characterizing the fate of inhaled pharmaceuticals
-
Patton JS, Brain JD, Davies LA et al (2010) The particle has landed -characterizing the fate of inhaled pharmaceuticals. J Aerosol Med 23:S71-S87
-
(2010)
J Aerosol Med
, vol.23
, pp. S71-S87
-
-
Patton, J.S.1
Brain, J.D.2
Davies, L.A.3
-
6
-
-
42649125889
-
Inhaled nanoparticles -a current review
-
Yang W, Peters JI, Williams RO 3rd (2008) Inhaled nanoparticles -a current review. Int J Pharm 356:239-247
-
(2008)
Int J Pharm
, vol.356
, pp. 239-247
-
-
Yang, W.1
Peters, J.I.2
Williams, R.O.3
-
7
-
-
77952698655
-
Electrospraying, spray drying and related techniques for production and formulation of drug nanoparticles
-
Peltonen L, Valo H, Kolakovic R et al (2010) Electrospraying, spray drying and related techniques for production and formulation of drug nanoparticles. Expert Opin Drug Deliv 7:705-719
-
(2010)
Expert Opin Drug Deliv
, vol.7
, pp. 705-719
-
-
Peltonen, L.1
Valo, H.2
Kolakovic, R.3
-
8
-
-
0017879956
-
The normal human lung: Ultrastructure and morphometric estimation of diffusion capacity
-
Gehr P, Bachofen M, Weibel ER (1978) The normal human lung: ultrastructure and morphometric estimation of diffusion capacity. Respir Physiol 32:121-140
-
(1978)
Respir Physiol
, vol.32
, pp. 121-140
-
-
Gehr, P.1
Bachofen, M.2
Weibel, E.R.3
-
9
-
-
0015609534
-
Morphological basis of alveolarcapillary gas exchange
-
Weibel ER (1973) Morphological basis of alveolarcapillary gas exchange. Physiol Rev 53:419-495
-
(1973)
Physiol Rev
, vol.53
, pp. 419-495
-
-
Weibel, E.R.1
-
11
-
-
21344471653
-
Cell culture models of the respiratory tract relevant to pulmonary drug delivery
-
Steimer A, Haltner E, Lehr CM (2005) Cell culture models of the respiratory tract relevant to pulmonary drug delivery. J Aerosol Med 18:137-182
-
(2005)
J Aerosol Med
, vol.18
, pp. 137-182
-
-
Steimer, A.1
Haltner, E.2
Lehr, C.M.3
-
12
-
-
73649135001
-
Airway regeneration: The role of the Clara cell secretory protein and the cells that express it
-
Wong AP, Keating A, Waddell TK (2009) Airway regeneration: the role of the Clara cell secretory protein and the cells that express it. Cytotherapy 11:676-687
-
(2009)
Cytotherapy
, vol.11
, pp. 676-687
-
-
Wong, A.P.1
Keating, A.2
Waddell, T.K.3
-
13
-
-
0019977498
-
Cell number and cell characteristics of the normal human lung
-
Crapo JD, Barry BE, Gehr P et al (1982) Cell number and cell characteristics of the normal human lung. Am Rev Respir Dis 126:332-337
-
(1982)
Am Rev Respir Dis
, vol.126
, pp. 332-337
-
-
Crapo, J.D.1
Barry, B.E.2
Gehr, P.3
-
14
-
-
0031740674
-
Pulmonary surfactant: Functions and molecular composition
-
Goerke J (1998) Pulmonary surfactant: functions and molecular composition. Biochim Biophys Acta 1408:79-89
-
(1998)
Biochim Biophys Acta
, vol.1408
, pp. 79-89
-
-
Goerke, J.1
-
15
-
-
77955440267
-
Update on macrophage clearance of inhaled micro-and nanoparticles
-
Geiser M (2010) Update on macrophage clearance of inhaled micro-and nanoparticles. J Aerosol Med 23:207-217
-
(2010)
J Aerosol Med
, vol.23
, pp. 207-217
-
-
Geiser, M.1
-
16
-
-
0026813472
-
Allometric relationships of cell numbers and size in the mammalian lung
-
Stone KC, Mercer RR, Gehr P et al (1992) Allometric relationships of cell numbers and size in the mammalian lung. Am J Respir Cell Mol Biol 6:235-243
-
(1992)
Am J Respir Cell Mol Biol
, vol.6
, pp. 235-243
-
-
Stone, K.C.1
Mercer, R.R.2
Gehr, P.3
-
17
-
-
1642502969
-
Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer
-
Geiser M, Schuerch S, Gehr P (2003) Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer. J Appl Physiol 94:1793-1801
-
(2003)
J Appl Physiol
, vol.94
, pp. 1793-1801
-
-
Geiser, M.1
Schuerch, S.2
Gehr, P.3
-
18
-
-
0025307779
-
Surfactant displaces particles toward the epithelium in airways and alveoli
-
Schuerch S, Gehr P, Im Hof V et al (1990) Surfactant displaces particles toward the epithelium in airways and alveoli. Respir Physiol 80:17-32
-
(1990)
Respir Physiol
, vol.80
, pp. 17-32
-
-
Schuerch, S.1
Gehr, P.2
Im Hof, V.3
-
19
-
-
60149089459
-
Barrier properties of mucus
-
Cone RA (2009) Barrier properties of mucus. Adv Drug Deliv Rev 61:75-85
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 75-85
-
-
Cone, R.A.1
-
20
-
-
36348985545
-
Functional imaging of mucociliary phenomena: High-speed digital reflection contrast microscopy
-
Ryser M, Burn A, Wessel T et al (2007) Functional imaging of mucociliary phenomena: high-speed digital reflection contrast microscopy. Eur Biophys J 37:35-54
-
(2007)
Eur Biophys J
, vol.37
, pp. 35-54
-
-
Ryser, M.1
Burn, A.2
Wessel, T.3
-
21
-
-
84875196483
-
Pulmonary drug metabolism, clearance, and absorption
-
Smyth HDC, Hickey AJ (eds), Springer, New York
-
Olsson B, Bondesson E, Borgstroem L (2011) Pulmonary drug metabolism, clearance, and absorption. In: Smyth HDC, Hickey AJ (eds) Controlled pulmonary drug delivery, 1st edn. Springer, New York, pp 21-50
-
(2011)
Controlled pulmonary drug delivery, 1st edn
, pp. 21-50
-
-
Olsson, B.1
Bondesson, E.2
Borgstroem, L.3
-
22
-
-
0343058935
-
Mechanisms of macromolecule absorption by the lungs
-
Patton JS (1996) Mechanisms of macromolecule absorption by the lungs. Adv Drug Deliv Rev 19:3-36
-
(1996)
Adv Drug Deliv Rev
, vol.19
, pp. 3-36
-
-
Patton, J.S.1
-
23
-
-
84878663137
-
Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues
-
Ensign LM, Henning A, Schneider CS et al (2013) Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues. Mol Pharm 10:2176-2182
-
(2013)
Mol Pharm
, vol.10
, pp. 2176-2182
-
-
Ensign, L.M.1
Henning, A.2
Schneider, C.S.3
-
24
-
-
84868599371
-
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
-
Kirch J, Schneider A, Abou B et al (2012) Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus. Proc Natl Acad Sci U S A 109:18355-18360
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 18355-18360
-
-
Kirch, J.1
Schneider, A.2
Abou, B.3
-
25
-
-
57049085726
-
Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier
-
Wang YY, Lai SK, Suk JS et al (2008) Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier. Angew Chem Int Ed Engl 47:9726-9729
-
(2008)
Angew Chem Int Ed Engl
, vol.47
, pp. 9726-9729
-
-
Wang, Y.Y.1
Lai, S.K.2
Suk, J.S.3
-
26
-
-
0028856079
-
Alveolar lining layer is thin and continuous: Low-temperature scanning electron microscopy of rat lung
-
Bastacky J, Lee CY, Goerke J et al (1995) Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung. J Appl Physiol 79:1615-1628
-
(1995)
J Appl Physiol
, vol.79
, pp. 1615-1628
-
-
Bastacky, J.1
Lee, C.Y.2
Goerke, J.3
-
27
-
-
34250832707
-
Biochemical and pharmacological differences between preparations of exogenous natural surfactant used to treat Respiratory Distress Syndrome: Role of the different components in an efficient pulmonary surfactant
-
Blanco O, Perez-Gil J (2007) Biochemical and pharmacological differences between preparations of exogenous natural surfactant used to treat Respiratory Distress Syndrome: role of the different components in an efficient pulmonary surfactant. Eur J Pharmacol 568:1-15
-
(2007)
Eur J Pharmacol
, vol.568
, pp. 1-15
-
-
Blanco, O.1
Perez-Gil, J.2
-
28
-
-
0034973011
-
Surfactant regulation of host defense function in the lung: A question of balance
-
Phelps DS (2001) Surfactant regulation of host defense function in the lung: a question of balance. Pediatr Pathol Mol Med 20:269-292
-
(2001)
Pediatr Pathol Mol Med
, vol.20
, pp. 269-292
-
-
Phelps, D.S.1
-
29
-
-
82255191648
-
Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A
-
Ruge CA, Kirch J, Canadas O et al (2011) Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A. Nanomedicine 7:690-693
-
(2011)
Nanomedicine
, vol.7
, pp. 690-693
-
-
Ruge, C.A.1
Kirch, J.2
Canadas, O.3
-
30
-
-
84863678205
-
The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles
-
Ruge CA, Schaefer UF, Herrmann J et al (2012) The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles. PLoS One 7:e40775
-
(2012)
PLoS One
, vol.7
-
-
Ruge, C.A.1
Schaefer, U.F.2
Herrmann, J.3
-
31
-
-
4544383493
-
Nanosuspensions in drug delivery
-
Rabinow BE (2004) Nanosuspensions in drug delivery. Nat Rev Drug Discov 3:785-796
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 785-796
-
-
Rabinow, B.E.1
-
32
-
-
77952686740
-
Generation and sizing of particles for aerosol-based nanotechnology
-
Biskos G, Vons V, Yurteri CU et al (2008) Generation and sizing of particles for aerosol-based nanotechnology. KONA Powder Part J 26:13-35
-
(2008)
KONA Powder Part J
, vol.26
, pp. 13-35
-
-
Biskos, G.1
Vons, V.2
Yurteri, C.U.3
-
33
-
-
74049124897
-
Spray drying technique. I. Hardware and process parameters
-
Cal K, Sollohub K (2010) Spray drying technique. I. Hardware and process parameters. J Pharm Sci 99:575-586
-
(2010)
J Pharm Sci
, vol.99
, pp. 575-586
-
-
Cal, K.1
Sollohub, K.2
-
34
-
-
74049124464
-
Spray drying technique: II. Current applications in pharmaceutical technology
-
Sollohub K, Cal K (2010) Spray drying technique: II. Current applications in pharmaceutical technology. J Pharm Sci 99:587-597
-
(2010)
J Pharm Sci
, vol.99
, pp. 587-597
-
-
Sollohub, K.1
Cal, K.2
-
36
-
-
42049094490
-
Pharmaceutical particle engineering via spray drying
-
Vehring R (2008) Pharmaceutical particle engineering via spray drying. Pharm Res 25:999-1022
-
(2008)
Pharm Res
, vol.25
, pp. 999-1022
-
-
Vehring, R.1
-
37
-
-
0037295176
-
Preparation of nanoparticles via spray route
-
Okuyama K, Lenggoro IW (2003) Preparation of nanoparticles via spray route. Chem Eng Sci 58: 537-547
-
(2003)
Chem Eng Sci
, vol.58
, pp. 537-547
-
-
Okuyama, K.1
Lenggoro, I.W.2
-
38
-
-
79651473099
-
Progress in developing spray-drying methods for the production of controlled morphology particles: From the nanometer to submicrometer size ranges
-
Nandiyanto ABD, Okuyama K (2011) Progress in developing spray-drying methods for the production of controlled morphology particles: from the nanometer to submicrometer size ranges. Adv Powder Technol 22:1-19
-
(2011)
Adv Powder Technol
, vol.22
, pp. 1-19
-
-
Nandiyanto, A.B.D.1
Okuyama, K.2
-
40
-
-
78650179651
-
Nano spray drying: A novel method for preparing protein nanoparticles for protein therapy
-
Lee SH, Heng D, Ng WK et al (2011) Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. Int J Pharm 403:192-200
-
(2011)
Int J Pharm
, vol.403
, pp. 192-200
-
-
Lee, S.H.1
Heng, D.2
Ng, W.K.3
-
41
-
-
33750842699
-
Powder formation by atmospheric spray-freeze-drying
-
Wang Z, Finlay WH, Peppler M et al (2006) Powder formation by atmospheric spray-freeze-drying. Powder Technol 170:45-52
-
(2006)
Powder Technol
, vol.170
, pp. 45-52
-
-
Wang, Z.1
Finlay, W.H.2
Peppler, M.3
-
42
-
-
0015566617
-
Ultrasonic atomization-a photographic study of the mechanism of disintegration
-
Topp MN (1973) Ultrasonic atomization-a photographic study of the mechanism of disintegration. J Aerosol Sci 4:17-25
-
(1973)
J Aerosol Sci
, vol.4
, pp. 17-25
-
-
Topp, M.N.1
-
43
-
-
79952937096
-
Producing pharmaceutical particles via electrospraying with an emphasis on nano and nano structured particles -a review
-
Yurteri CU, Hartman RPA, Marijnissen JCM (2010) Producing pharmaceutical particles via electrospraying with an emphasis on nano and nano structured particles -a review. KONA Powder Part J 28:91-115
-
(2010)
KONA Powder Part J
, vol.28
, pp. 91-115
-
-
Yurteri, C.U.1
Hartman, R.P.A.2
Marijnissen, J.C.M.3
-
44
-
-
0036374126
-
Spray freeze-drying -the process of choice for low water soluble drugs?
-
Leuenberger H (2002) Spray freeze-drying -the process of choice for low water soluble drugs? J Nanopart Res 4:111-119
-
(2002)
J Nanopart Res
, vol.4
, pp. 111-119
-
-
Leuenberger, H.1
-
45
-
-
78650677959
-
Spray-freezedrying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants
-
Cheow WS, Ng ML, Kho K et al (2011) Spray-freezedrying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: effect of freeze-drying adjuvants. Int J Pharm 404:289-300
-
(2011)
Int J Pharm
, vol.404
, pp. 289-300
-
-
Cheow, W.S.1
Ng, M.L.2
Kho, K.3
-
46
-
-
33747092689
-
Straightforward biodegradable nanoparticle generation through megahertz-order ultrasonic atomization
-
Forde G, Friend J, Williamson T (2006) Straightforward biodegradable nanoparticle generation through megahertz-order ultrasonic atomization. Appl Phys Lett 89:064105-064105-3
-
(2006)
Appl Phys Lett
, vol.89
-
-
Forde, G.1
Friend, J.2
Williamson, T.3
-
47
-
-
0032903845
-
Ultrasonic atomization for spray drying: A versatile technique for the preparation of protein loaded biodegradable microspheres
-
Bittner B, Kissel T (1999) Ultrasonic atomization for spray drying: a versatile technique for the preparation of protein loaded biodegradable microspheres. J Microencapsul 16:325-341
-
(1999)
J Microencapsul
, vol.16
, pp. 325-341
-
-
Bittner, B.1
Kissel, T.2
-
48
-
-
0033230727
-
Strategies for particle design using supercritical fluid technologies
-
York P (1999) Strategies for particle design using supercritical fluid technologies. Pharm Sci Technol Today 2:430-440
-
(1999)
Pharm Sci Technol Today
, vol.2
, pp. 430-440
-
-
York, P.1
-
49
-
-
1442348833
-
Solid dispersion of carbamazepine in PVP K30 by conventional solvent evaporation and supercritical methods
-
Sethia S, Squillante E (2004) Solid dispersion of carbamazepine in PVP K30 by conventional solvent evaporation and supercritical methods. Int J Pharm 272:1-10
-
(2004)
Int J Pharm
, vol.272
, pp. 1-10
-
-
Sethia, S.1
Squillante, E.2
-
50
-
-
39149086684
-
Nanoparticles synthesis using supercritical fluid technology -towards biomedical applications
-
Byrappa K, Ohara S, Adschiri T (2008) Nanoparticles synthesis using supercritical fluid technology -towards biomedical applications. Adv Drug Deliv Rev 60:299-327
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 299-327
-
-
Byrappa, K.1
Ohara, S.2
Adschiri, T.3
-
51
-
-
34447114484
-
Micro-and nanoparticle production by electrospraying
-
Jaworek A (2007) Micro-and nanoparticle production by electrospraying. Powder Technol 176:18-35
-
(2007)
Powder Technol
, vol.176
, pp. 18-35
-
-
Jaworek, A.1
-
52
-
-
0033180937
-
The surface charge in electrospraying: Its nature and its universal scaling laws
-
Ganan-Calvo AM (1999) The surface charge in electrospraying: its nature and its universal scaling laws. J Aerosol Sci 30:863-872
-
(1999)
J Aerosol Sci
, vol.30
, pp. 863-872
-
-
Ganan-Calvo, A.M.1
-
53
-
-
39849090289
-
Electrospraying route to nanotechnology: An overview
-
Jaworek A, Sobczyk AT (2008) Electrospraying route to nanotechnology: an overview. J Electrostat 66:197-219
-
(2008)
J Electrostat
, vol.66
, pp. 197-219
-
-
Jaworek, A.1
Sobczyk, A.T.2
-
54
-
-
79958033399
-
Nanoparticles in medicine and environment: Inhalation and health effects
-
Marijnissen JCM, Gradon L (2010) Nanoparticles in medicine and environment: inhalation and health effects. J Aerosol Med 23:339-341
-
(2010)
J Aerosol Med
, vol.23
, pp. 339-341
-
-
Marijnissen, J.C.M.1
Gradon, L.2
-
55
-
-
77950518265
-
One-step electrohydrodynamic production of drug-loaded micro-and nanoparticles
-
Enayati M, Ahmad Z, Stride E et al (2010) One-step electrohydrodynamic production of drug-loaded micro-and nanoparticles. J R Soc Interface 7:667-675
-
(2010)
J R Soc Interface
, vol.7
, pp. 667-675
-
-
Enayati, M.1
Ahmad, Z.2
Stride, E.3
-
56
-
-
69049088947
-
Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles
-
Valo H, Peltonen L, Vehvilaeinen S et al (2009) Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles. Small 5:1791-1798
-
(2009)
Small
, vol.5
, pp. 1791-1798
-
-
Valo, H.1
Peltonen, L.2
Vehvilaeinen, S.3
-
57
-
-
0022889862
-
Deposition of particles in the human respiratory tract in the size range 0.005-15 μm
-
Heyder J, Gebhardt J, Rudolf G et al (1986) Deposition of particles in the human respiratory tract in the size range 0.005-15 μm. J Aerosol Sci 17:811-825
-
(1986)
J Aerosol Sci
, vol.17
, pp. 811-825
-
-
Heyder, J.1
Gebhardt, J.2
Rudolf, G.3
-
58
-
-
18144385104
-
Novel sustained release microspheres for pulmonary drug delivery
-
Cook RO, Pannu RK, Kellaway IW (2005) Novel sustained release microspheres for pulmonary drug delivery. J Control Release 104:79-90
-
(2005)
J Control Release
, vol.104
, pp. 79-90
-
-
Cook, R.O.1
Pannu, R.K.2
Kellaway, I.W.3
-
59
-
-
34548014773
-
Preparation of drug nanoparticle-containing microparticles using a 4-fluid nozzle spray drier for oral, pulmonary, and injection dosage forms
-
Mizoe T, Ozeki T, Okada H (2007) Preparation of drug nanoparticle-containing microparticles using a 4-fluid nozzle spray drier for oral, pulmonary, and injection dosage forms. J Control Release 122:10-15
-
(2007)
J Control Release
, vol.122
, pp. 10-15
-
-
Mizoe, T.1
Ozeki, T.2
Okada, H.3
-
60
-
-
33847261116
-
Effervescent dry powder for respiratory drug delivery
-
Ely L, Roa W, Finlay WH et al (2007) Effervescent dry powder for respiratory drug delivery. Eur J Pharm Biopharm 65:346-353
-
(2007)
Eur J Pharm Biopharm
, vol.65
, pp. 346-353
-
-
Ely, L.1
Roa, W.2
Finlay, W.H.3
-
61
-
-
34547554369
-
Engineering of poly(DL-lactic-co-glycolic acid) nanocomposite particles for dry powder inhalation dosage forms of insulin with the spray-fluidized bed granulating system
-
Yamamoto H, Hoshina W, Kurashima H et al (2007) Engineering of poly(DL-lactic-co-glycolic acid) nanocomposite particles for dry powder inhalation dosage forms of insulin with the spray-fluidized bed granulating system. Adv Powder Technol 18:215-228
-
(2007)
Adv Powder Technol
, vol.18
, pp. 215-228
-
-
Yamamoto, H.1
Hoshina, W.2
Kurashima, H.3
-
62
-
-
33745904988
-
Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles
-
Azarmi S, Tao X, Chen H et al (2006) Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles. Int J Pharm 319:155-161
-
(2006)
Int J Pharm
, vol.319
, pp. 155-161
-
-
Azarmi, S.1
Tao, X.2
Chen, H.3
-
63
-
-
20744434748
-
Microencapsulated chitosan nanoparticles for lung protein delivery
-
Grenha A, Seijo B, Remunan-Lopez C (2005) Microencapsulated chitosan nanoparticles for lung protein delivery. Eur J Pharm Sci 25:427-437
-
(2005)
Eur J Pharm Sci
, vol.25
, pp. 427-437
-
-
Grenha, A.1
Seijo, B.2
Remunan-Lopez, C.3
-
64
-
-
0347360189
-
Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung
-
Sham JOH, Zhang Y, Finlay WH et al (2004) Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung. Int J Pharm 269:457-467
-
(2004)
Int J Pharm
, vol.269
, pp. 457-467
-
-
Sham, J.O.H.1
Zhang, Y.2
Finlay, W.H.3
-
65
-
-
34447637784
-
Drug release study of large hollow nanoparticulate aggregates carrier particles for pulmonary delivery
-
Hadinoto K, Zhu K, Tan RBH (2007) Drug release study of large hollow nanoparticulate aggregates carrier particles for pulmonary delivery. Int J Pharm 341:195-206
-
(2007)
Int J Pharm
, vol.341
, pp. 195-206
-
-
Hadinoto, K.1
Zhu, K.2
Tan, R.B.H.3
-
66
-
-
76749153731
-
Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
-
Jensen DMK, Cun D, Maltesen MJ et al (2010) Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. J Control Release 142:138-145
-
(2010)
J Control Release
, vol.142
, pp. 138-145
-
-
Jensen, D.M.K.1
Cun, D.2
Maltesen, M.J.3
-
67
-
-
0037126053
-
Trojan particles: Large porous carriers of nanoparticles for drug delivery
-
Tsapis N, Bennett D, Jackson B et al (2002) Trojan particles: large porous carriers of nanoparticles for drug delivery. Proc Natl Acad Sci U S A 99:12001-12005
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12001-12005
-
-
Tsapis, N.1
Bennett, D.2
Jackson, B.3
-
68
-
-
26944474854
-
Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery
-
Heyder J (2004) Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery. Proc Am Thorac Soc 1:315-320
-
(2004)
Proc Am Thorac Soc
, vol.1
, pp. 315-320
-
-
Heyder, J.1
-
69
-
-
84862668679
-
Controlled pulmonary drug and gene delivery using polymeric nano-carriers
-
Beck-Broichsitter M, Merkel OM, Kissel T (2012) Controlled pulmonary drug and gene delivery using polymeric nano-carriers. J Control Release 161:214-224
-
(2012)
J Control Release
, vol.161
, pp. 214-224
-
-
Beck-Broichsitter, M.1
Merkel, O.M.2
Kissel, T.3
-
70
-
-
84858704235
-
Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery
-
Beck-Broichsitter M, Schweiger C, Schmehl T et al (2012) Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery. J Control Release 158:329-335
-
(2012)
J Control Release
, vol.158
, pp. 329-335
-
-
Beck-Broichsitter, M.1
Schweiger, C.2
Schmehl, T.3
-
71
-
-
85027934512
-
Following the concentration of polymeric nanoparticles during nebulization
-
Beck-Broichsitter M, Knuedeler MC, Schmehl T et al (2013) Following the concentration of polymeric nanoparticles during nebulization. Pharm Res 30:16-24
-
(2013)
Pharm Res
, vol.30
, pp. 16-24
-
-
Beck-Broichsitter, M.1
Knuedeler, M.C.2
Schmehl, T.3
-
72
-
-
52149103782
-
Current therapies and technological advances in aqueous aerosol drug delivery
-
Watts AB, McConville JT, Williams RO III (2008) Current therapies and technological advances in aqueous aerosol drug delivery. Drug Dev Ind Pharm 34:913-922
-
(2008)
Drug Dev Ind Pharm
, vol.34
, pp. 913-922
-
-
Watts, A.B.1
McConville, J.T.2
Williams, R.O.3
-
74
-
-
20444378183
-
Human respiratory epithelial cell culture for drug delivery applications
-
Forbes B, Ehrhardt C (2005) Human respiratory epithelial cell culture for drug delivery applications. Eur J Pharm Biopharm 60:193-205
-
(2005)
Eur J Pharm Biopharm
, vol.60
, pp. 193-205
-
-
Forbes, B.1
Ehrhardt, C.2
-
75
-
-
79952310806
-
An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier
-
Lehmann A, Daum N, Bur M et al (2011) An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier. Eur J Pharm Biopharm 77:398-406
-
(2011)
Eur J Pharm Biopharm
, vol.77
, pp. 398-406
-
-
Lehmann, A.1
Daum, N.2
Bur, M.3
-
76
-
-
58949098172
-
A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles
-
Rothen-Rutishauser B, Mueller L, Blank F et al (2008) A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles. ALTEX 25:191-196
-
(2008)
ALTEX
, vol.25
, pp. 191-196
-
-
Rothen-Rutishauser, B.1
Mueller, L.2
Blank, F.3
-
77
-
-
79960510296
-
In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung -a dialog between aerosol science and biology
-
Paur HR, Cassee FR, Teeguarden JG et al (2011) In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung -a dialog between aerosol science and biology. J Aerosol Sci 42:668-692
-
(2011)
J Aerosol Sci
, vol.42
, pp. 668-692
-
-
Paur, H.R.1
Cassee, F.R.2
Teeguarden, J.G.3
-
78
-
-
77955222448
-
A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles
-
Lenz A, Karg E, Lentner B et al (2009) A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles. Part Fibre Toxicol 6:32
-
(2009)
Part Fibre Toxicol
, vol.6
, pp. 32
-
-
Lenz, A.1
Karg, E.2
Lentner, B.3
-
79
-
-
78650715310
-
A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations
-
Hein S, Bur M, Schaefer UF et al (2011) A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations. Eur J Pharm Biopharm 77:132-138
-
(2011)
Eur J Pharm Biopharm
, vol.77
, pp. 132-138
-
-
Hein, S.1
Bur, M.2
Schaefer, U.F.3
-
80
-
-
79952160334
-
Evaluating the controlled release properties of inhaled nanoparticles using isolated, perfused, and ventilated lung models
-
article ID 163791
-
Beck-Broichsitter M, Schmehl T, Seeger W et al (2011) Evaluating the controlled release properties of inhaled nanoparticles using isolated, perfused, and ventilated lung models. J Nanomaterials 2011:1-16, article ID 163791
-
(2011)
J Nanomaterials
, vol.2011
, pp. 1-16
-
-
Beck-Broichsitter, M.1
Schmehl, T.2
Seeger, W.3
-
81
-
-
33750845387
-
In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery
-
Sakagami M (2006) In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery. Adv Drug Deliv Rev 58:1030-1060
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 1030-1060
-
-
Sakagami, M.1
-
82
-
-
58249113936
-
Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model
-
Beck-Broichsitter M, Gauss J, Packhaeuser CB et al (2009) Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model. Int J Pharm 367:169-178
-
(2009)
Int J Pharm
, vol.367
, pp. 169-178
-
-
Beck-Broichsitter, M.1
Gauss, J.2
Packhaeuser, C.B.3
-
83
-
-
76649145422
-
Pulmonary targeting with biodegradable salbutamolloaded nanoparticles
-
Beck-Broichsitter M, Gauss J, Gessler T et al (2010) Pulmonary targeting with biodegradable salbutamolloaded nanoparticles. J Aerosol Med 23:47-57
-
(2010)
J Aerosol Med
, vol.23
, pp. 47-57
-
-
Beck-Broichsitter, M.1
Gauss, J.2
Gessler, T.3
-
84
-
-
70849084242
-
In vitro and in vivo performance of biocompatible negativelycharged salbutamol-loaded nanoparticles
-
Rytting E, Bur M, Cartier R et al (2010) In vitro and in vivo performance of biocompatible negativelycharged salbutamol-loaded nanoparticles. J Control Release 141:101-107
-
(2010)
J Control Release
, vol.141
, pp. 101-107
-
-
Rytting, E.1
Bur, M.2
Cartier, R.3
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