Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer

Journal of Applied Physiology

Volumn 94, Issue 5, 2003, Pages 1793-1801

  Geiser, Marianne ^a   Schürch, Samuel ^b   Gehr, Peter ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Aerosols; Inhalation; Macrophages; Respiratory tract; Surfactant

Indexed keywords

LUNG SURFACTANT; POLITEF; POLYSTYRENE;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMISTRY; ELECTRON MICROSCOPY; EPITHELIUM CELL; FUNGUS SPORE; HAMSTER; IMMERSION; INHALATION; LUNG ALVEOLUS; LUNG ALVEOLUS SURFACE TENSION; MACROPHAGE; MALE; MICROSCOPY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RESPIRATORY SYSTEM;

EID: 1642502969     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00514.2002     Document Type: Article

References (36)

1. Bachofen H, Ammann A, Wangensteen D, and Weibel ER. Perfusion fixation of lungs for structure-function analysis: credits and limitations. J Appl Physiol 53: 528-533, 1982.
2. Bachofen H, Gerber U, and Schürch S. Effects of fixatives on function of pulmonary surfactant. J Appl Physiol 93: 911-916, 2002.
3. Bachofen H and Schürch S. Alveolar surface forces and lung architecture. Comp Biochem Physiol A 129: 183-193, 2001.
4. Bachofen H, Schürch S, Urbinelli M, and Weibel ER. Relations among alveolar surface tension, surface area, volume and recoil pressure in rabbit lungs. J Appl Physiol 62: 1878-1887, 1987.
5. Bartnicki-Garcia S. Cell wall chemistry, morphogenesis, and taxonomy of fungi. Annu Rev Microbiol 22: 87-108, 1968.
6. Churg A. Particle uptake by epithelial cells. In: Particle-Lung Interaction, edited by Gehr P, Heyder. New York: Dekker, 2000, vol. 143, p. 401-435.
7. Gehr P, Schürch S, Berthiaume Y, Im Hof V, and Geiser M. Particle retention in airways by surfactant. J Aerosol Med 3: 27-43, 1990.
8. Geiser M, Cruz-Orive LM, Im Hof V, and Gehr P. Assessment of particle retention and clearance in the intrapulmonary conducting airways of hamster lungs with the fractionator. J Microsc 160: 75-88, 1990.
9. Geiser M, Cruz-Orive LM, Waber U, Im Hof V, and Gehr P. Particle retention in airways estimated by unbiased stereology and photometry. J Aerosol Med 8: 149-165, 1995.
10. Geiser M, Gerber P, Maye I, Im Hof V, and Gehr P. Retention of teflon particles in hamster lungs: a stereologic study. J Aerosol Med 13: 43-55, 2000.
11. Geiser M, Im Hof V, Siegenthaler W, Grunder R, and Gehr P. Ultrastructure of the extracellular lining layer in hamster airways: is there a two-phase system? Microsc Res Tech 36: 428-437, 1997.
12. Geiser M, Leupin N, Maye I, Im Hof V, and Gehr P. Interaction of fungal spores with the lungs: distribution and retention of inhaled Calvatia excipuliformis spores. J Allergy Clin Immunol 106: 92-100, 2000.
13. Gil J and Weibel ER. Extracellular lining of bronchioles after perfusion-fixation of rat lungs for electron microscopy. Anat Rec 169: 185-200, 1971.
14. Green FHY, Gehr P, Lee MM, and Schürch S. The role of surfactant in disease associated with particle exposure. In: Particle-Lung Interaction, edited by Gehr P, Heyder. New York: Marcel Dekker, 2000, vol. 143, p. 533-576.
15. Griffin DH. Fungal Physiology. New York: Wiley, 1981, p. 18-72.
16. Harmsen AG, Muggenburg BA, Snipes MB, and Bice DE. The role of macrophages in particle translocation from lungs to lymph nodes. Science 230: 1277-1280, 1985.
17. Hunsley D and Burnett JH. The ultrastructural architecture of the walls of some hyphal fungi. J Gen Microbiol 62: 203-218, 1970.
18. Im Hof V, Gehr P, Gerber V, Lee MM, and Schürch S. In vivo determination of surface tension in the horse and in vitro model studies. Respir Physiol 109: 81-93, 1997.
19. Im Hof V and Patrick G. Particle retention and clearance. J Aerosol Med 7: 39-47, 1994.
20. Im Hof V, Scheuch G, Geiser M, Gebhart J, Gehr P, and Heyder J. Techniques for the determination of particle deposition in lungs of hamsters. J Aerosol Med 2: 247-259, 1989.
21. Li D and Neumann AW. Wettability and surface tension of particles. In: Applied Surface Thermodynamics, edited by Neumann AW and Spelt JK. New York: Dekker, 1996, vol. 63, p. 509-556.
22. Neinhuis C and Barthlott W. Characterization and distribution of water-repellent, self-cleaning plant surfaces. Annals Botany 79: 667-677, 1997.
23. Neumann AW, Absolom DR, Francis DW, Omenyi SN, Spelt JK, Policova Z, Thomson C, Zingg W, and Van Oss CJ. Measurement of surface tension of blood cells and proteins. Ann NY Acad Sci 416: 276-298, 1983.
24. Oberdörster G, Ferin J, and Lehnert BE. Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect 102, Suppl 5: 173-179, 1994.
25. Oliver JF, Huh C, and Mason SG. Resistance to spreading of liquids by sharp edges. J Colloid Interface Sci 59: 568-581, 1977.
26. Philipson K. Monodisperse labeled aerosols for studies of lung clearance. In: Abstracts of Uppsala Dissertations from the Faculty of Science Uppsala: University of Uppsala. Uppsala, Sweden: Univ. of Uppsala, 1977, vol. 433, p. 1-36.
27. Pinkerton KE, Gallen JT, Mercer RR, Wong VC, Plopper CG, and Tarkington BK. Aerosolized fluorescent microspheres detected in the lung using confocal scanning laser microscopy. Microsc Res Tech 26: 437-443, 1993.
28. Schürch S, Bachofen H, Goerke J, and Green F. Surface properties of rat pulmonary surfactant studied with a captive bubble method: adsorption, hysteresis, stability. Biochim Biophys Acta 1103: 127-136, 1992.
29. Schürch S, Bachofen H, and Weibel ER. Alveolar surface tension in excised rabbit lungs: effect of temperature. Respir Physiol 62: 31-45, 1985.
30. Schürch S, Gehr P, Im Hof V, Geiser M, and Green F. Surfactant displaces particles toward the epithelium in airways and alveoli. Respir Physiol 80: 17-32, 1990.
31. Schürch S, Goerke J, and Clements JA. Direct determination of volume- and time-dependence of alveolar surface tension in excised lungs. Proc Natl Acad Sci USA 75: 3417-3421, 1978.
32. Schürch S, Green FHY, and Bachofen H. Formation and structure of surfactant films: captive bubble surfactometry. Biochim Biophys Acta 1408: 180-202, 1998.
33. Spelt JK and Li D. The equation of state approach to interfacial tension. In: Applied Surface Thermodynamics, edited by Neumann AW and Spelt JK. New York: Dekker, 1996, vol. 63, p. 239-292.
34. Stirling C and Patrick G. The localisation of particles retained in the trachea of the rat. J Pathol 131: 309-320, 1980.
35. Sweeney TD, Brain JD, and LeMott S. Anesthesia alters the pattern of aerosol retention in hamsters. J Appl Physiol 54: 37-44, 1983.
36. Waber U, Im Hof V, Geiser M, Baumann M, Scheuch G, Gebhart J, Stahlhofen W, and Gehr P. A new methodology for controlled particle inhalation by small rodents. Exp Lung Res 25: 113-125, 1999.