Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier

Angewandte Chemie - International Edition

Volumn 47, Issue 50, 2008, Pages 9726-9729

  Wang, Ying Ying ^a   Lai, Samuel K ^a   Suk, Jung Soo ^a   Pace, Amanda ^a   Cone, Richard ^b   Hanes, Justin ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Johns Hopkins University

Author keywords

Drug delivery; Mucosal tissues; Nanomedicine; Particle tracking; Surface chemistry

Indexed keywords

ADHESIVE INTERACTIONS; COATED PARTICLES; MUCOSAL TISSUES; NANOMEDICINE; PARTICLE TRACKING; POLY(ETHYLENE GLYCOL);

BODY FLUIDS; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; GLYCOLS; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; POLYETHYLENE OXIDES; SURFACE CHEMISTRY;

POLYETHYLENE GLYCOLS;

MACROGOL DERIVATIVE; NANOPARTICLE;

ARTICLE; CHEMICAL ENGINEERING; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR WEIGHT; MUCUS;

CHEMICAL ENGINEERING; HUMANS; MOLECULAR WEIGHT; MUCUS; NANOPARTICLES; POLYETHYLENE GLYCOLS;

EID: 57049085726     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200803526     Document Type: Article

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