Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants

International Journal of Pharmaceutics

Volumn 404, Issue 1-2, 2011, Pages 289-300

  Cheow, Wean Sin ^a   Ng, Mabel Li Ling ^a   Kho, Katherine ^a   Hadinoto, Kunn ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Coalescence; Dry powder inhaler; Nanoparticles; Poly(caprolactone); Spray freeze drying

Indexed keywords

LACTOSE; LEUCINE; LEVOFLOXACIN; MANNITOL; NANOPARTICLE; POLYCAPROLACTONE; POLYVINYL ALCOHOL;

AEROSOL; ARTICLE; DENSITY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRY POWDER; FLOW RATE; FREEZE DRYING; INHALER; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ADMINISTRATION, INHALATION; ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; EXCIPIENTS; FREEZE DRYING; LACTOSE; LEUCINE; MANNITOL; NANOPARTICLES; NANOTECHNOLOGY; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE; POLYESTERS; POLYVINYL ALCOHOL; POROSITY; POWDERS; RHEOLOGY; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 78650677959     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.11.021     Document Type: Article

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