Preparation of drug nanoparticle-containing microparticles using a 4-fluid nozzle spray drier for oral, pulmonary, and injection dosage forms

Journal of Controlled Release

Volumn 122, Issue 1, 2007, Pages 10-15

  Mizoe, Takuto ^a   Ozeki, Tetsuya ^a   Okada, Hiroaki ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

4 fluid nozzle; Insoluble drug; Microparticle; Nanoparticle; Spray dry

Indexed keywords

FLUID NOZZLES; INSOLUBLE DRUGS; ORAL ADMINISTRATION; SPRAY DRIERS;

AEROSOLS; CONCENTRATION (PROCESS); DRUG DOSAGE; DRUG PRODUCTS; SPRAY DRYING; TISSUE;

NANOPARTICLES;

LEUKOTRIENE DERIVATIVE; NANOPARTICLE; PRANLUKAST HEMIHYDRATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DRUG ABSORPTION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOENDOTHELIAL SYSTEM;

ADMINISTRATION, INHALATION; ADMINISTRATION, ORAL; AEROSOLS; ANIMALS; ANTI-ASTHMATIC AGENTS; CHROMONES; LUNG; MALE; MANNITOL; MICROSCOPY, ELECTRON, SCANNING; MOUTH MUCOSA; NANOPARTICLES; PARTICLE SIZE; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; SUSPENSIONS; X-RAY DIFFRACTION;

EID: 34548014773     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.06.001     Document Type: Article

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