A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 1, 2011, Pages 132-138

  Hein, Stephanie ^a   Bur, Michael ^a   Schaefer, Ulrich F ^a   Lehr, Claus Michael ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Aerosol medicine; Air liquid interface; Calu 3 cells; In vitro model; Sedimentation

Indexed keywords

BUDESONIDE; CYCLOCAPS; SALBUTAMOL SULFATE; UNCLASSIFIED DRUG;

AEROSOL; ARTICLE; CELL CULTURE; DOSE RESPONSE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; DRY POWDER; LUNG ALVEOLUS EPITHELIUM; METERED DOSE INHALER; PHARMACEUTICAL AEROSOL DEPOSITION DEVICE ON CELL CULTURE;

ABSORPTION; ADMINISTRATION, INHALATION; AEROSOLS; ALBUTEROL; ANIMAL USE ALTERNATIVES; BIOLOGICAL TRANSPORT; BLOOD-AIR BARRIER; BRONCHODILATOR AGENTS; BUDESONIDE; CELL CULTURE TECHNIQUES; CELL LINE; DRUG CARRIERS; DRY POWDER INHALERS; ELECTRIC IMPEDANCE; HUMANS; METERED DOSE INHALERS; POWDERS; RESPIRATORY MUCOSA; SOLUBILITY;

EID: 78650715310     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.10.003     Document Type: Article

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