MicroRNA-133 modulates the β1-adrenergic receptor transduction cascade

Circulation Research

Volumn 115, Issue 2, 2014, Pages 273-283

  Castaldi, Alessandra ^a,c   Zaglia, Tania ^d,e   Di Mauro, Vittoria ^a   Carullo, Pierluigi ^a   Viggiani, Giacomo ^a   Borile, Giulia ^d,e   Di Stefano, Barbara ⁱ   Schiattarella, Gabriele Giacomo ^f,g   Gualazzi, Maria Giovanna ^a   Elia, Leonardo ^b   Stirparo, Giuliano Giuseppe ^a   Colorito, Maria Luisa ⁱ   Pironti, Gianluigi ^h   Kunderfranco, Paolo ^a   Esposito, Giovanni ^f   Bang, Marie Louise ^a   Mongillo, Marco ^d,e   Condorelli, Gianluigi ^a,g   Catalucci, Daniele ^a  

^a Milan Unit   (Italy)

^b IRCCS MULTIMEDICA   (Italy)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^e UNIVERSITY OF PADOVA   (Italy)

^f UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^g UNIVERSITY OF MILAN   (Italy)

^h DUKE UNIVERSITY MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF PALERMO   (Italy)

Author keywords

adrenergic beta 1 receptor antagonists; cardiac; cyclic AMP; heart failure; microRNAs; myocytes

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE VI; BETA 1 ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; MICRORNA; MICRORNA 133; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ADENYLYL CYCLASE 6; CYCLIC AMP DEPENDENT PROTEIN KINASE; EPAC PROTEIN, MOUSE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYBRID PROTEIN; MESSENGER RNA; METOPROLOL; MIRN133 MICRORNA, MOUSE;

APOPTOSIS; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVE SITE; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PERFORMANCE; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; VALIDATION PROCESS; 3' UNTRANSLATED REGION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RAT; REPORTER GENE; SECOND MESSENGER; SPRAGUE DAWLEY RAT;

3' UNTRANSLATED REGIONS; ADENYLATE CYCLASE; ANIMALS; APOPTOSIS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE PROGRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MALE; METOPROLOL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA-1; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SECOND MESSENGER SYSTEMS;

EID: 84904040454     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.303252     Document Type: Article

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