Involvement of oxidative stress-induced DNA damage, endoplasmic reticulum stress, and autophagy deficits in the decline of β-cell mass in Japanese type 2 diabetic patients

Diabetes Care

Volumn 37, Issue 7, 2014, Pages 1966-1974

  Mizukami, Hiroki ^a   Takahashi, Kazunori ^a   Inaba, Wataru ^a   Tsuboi, Kentaro ^a   Osonoi, Sho ^a   Yoshida, Taro ^a   Yagihashi, Soroku ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER 1 BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN BETA; HEMOGLOBIN A1C; HISTONE H2AX; INSULIN; ORAL ANTIDIABETIC AGENT; PROTEIN GAMMA H2AX; PROTEIN P62; UNCLASSIFIED DRUG;

AGED; APOPTOSIS; ARTICLE; AUTOPHAGY; BODY MASS; CAUSE OF DEATH; CELL PROLIFERATION; CELL VOLUME; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETOGENESIS; DIET THERAPY; DISEASE ASSOCIATION; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; JAPANESE (PEOPLE); MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; ASIAN CONTINENTAL ANCESTRY GROUP; AUTOPSY; JAPAN; METABOLISM; MIDDLE AGED; PANCREAS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; AUTOPHAGY; AUTOPSY; DIABETES MELLITUS, TYPE 2; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMANS; INSULIN-SECRETING CELLS; JAPAN; MALE; MIDDLE AGED; OXIDATIVE STRESS; PANCREAS;

EID: 84903516492     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc13-2018     Document Type: Article

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