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Volumn 11, Issue 1, 2014, Pages

Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies

Author keywords

Acute transmitted founder envelopes; Broadly neutralizing antibodies; CCR5; CD4; Receptor affinity profiling; Receptor usage efficiency; Subtype C; Virus entry

Indexed keywords

CD4 ANTIBODY; CHEMOKINE RECEPTOR CCR5; ENHANCED GREEN FLUORESCENT PROTEIN; NEUTRALIZING ANTIBODY; REV PROTEIN; TRANSACTIVATOR PROTEIN; CCR5 PROTEIN, HUMAN; CD4 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

EID: 84902706979     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-11-48     Document Type: Article
Times cited : (22)

References (97)
  • 2
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med 1997, 185:621-628.
    • (1997) J Exp Med , vol.185 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3    Choe, S.4    Landau, N.R.5
  • 4
    • 0037326239 scopus 로고    scopus 로고
    • Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance
    • Spira S, Wainberg M, Loemba H, Turner D, Brenner B. Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance. J Antimicrob Chemoth 2003, 51:229-240.
    • (2003) J Antimicrob Chemoth , vol.51 , pp. 229-240
    • Spira, S.1    Wainberg, M.2    Loemba, H.3    Turner, D.4    Brenner, B.5
  • 5
    • 79952699891 scopus 로고    scopus 로고
    • Coreceptors and HIV-1 Pathogenesis
    • Gorry PR, Ancuta P. Coreceptors and HIV-1 Pathogenesis. Curr HIV/AIDS Rep 2010, 8:45-53.
    • (2010) Curr HIV/AIDS Rep , vol.8 , pp. 45-53
    • Gorry, P.R.1    Ancuta, P.2
  • 8
    • 0034652603 scopus 로고    scopus 로고
    • Susceptibility of in vitro stimulated PBMC to infection with NSI HIV-1 is associated with levels of CCR5 expression and beta-chemokine production
    • Blaak H, Ran LJ, Rientsma R, Schuitemaker H. Susceptibility of in vitro stimulated PBMC to infection with NSI HIV-1 is associated with levels of CCR5 expression and beta-chemokine production. Virology 2000, 267:237-246.
    • (2000) Virology , vol.267 , pp. 237-246
    • Blaak, H.1    Ran, L.J.2    Rientsma, R.3    Schuitemaker, H.4
  • 9
    • 0032731642 scopus 로고    scopus 로고
    • Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates
    • Li S, Juarez J, Alali M, Dwyer D, Collman R, Cunningham A, Naif HM. Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates. J Virol 1999, 73:9741-9755.
    • (1999) J Virol , vol.73 , pp. 9741-9755
    • Li, S.1    Juarez, J.2    Alali, M.3    Dwyer, D.4    Collman, R.5    Cunningham, A.6    Naif, H.M.7
  • 11
    • 0035864287 scopus 로고    scopus 로고
    • Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants
    • Smit TK, Wang B, Ng T, Osborne R, Brew B, Saksena NK. Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants. Virology 2001, 279:509-526.
    • (2001) Virology , vol.279 , pp. 509-526
    • Smit, T.K.1    Wang, B.2    Ng, T.3    Osborne, R.4    Brew, B.5    Saksena, N.K.6
  • 12
    • 20444395434 scopus 로고    scopus 로고
    • Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome
    • Gray L, Sterjovski J, Churchill M, Ellery P, Nasr N, Lewin SR, Crowe SM, Wesselingh SL, Cunningham AL, Gorry PR. Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome. Virology 2005, 337:384-398.
    • (2005) Virology , vol.337 , pp. 384-398
    • Gray, L.1    Sterjovski, J.2    Churchill, M.3    Ellery, P.4    Nasr, N.5    Lewin, S.R.6    Crowe, S.M.7    Wesselingh, S.L.8    Cunningham, A.L.9    Gorry, P.R.10
  • 13
    • 84897019003 scopus 로고    scopus 로고
    • HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategies
    • Gorry PR, Francella N, Lewin SR, Collman RG. HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategies. J Leukoc Biol 2014, 95:71-81.
    • (2014) J Leukoc Biol , vol.95 , pp. 71-81
    • Gorry, P.R.1    Francella, N.2    Lewin, S.R.3    Collman, R.G.4
  • 19
    • 0032904012 scopus 로고    scopus 로고
    • HIV-1 envelope determinants for cell tropism and chemokine receptor use
    • Hoffman TL, Doms RW. HIV-1 envelope determinants for cell tropism and chemokine receptor use. Mol Membr Biol 1999, 16:57-65.
    • (1999) Mol Membr Biol , vol.16 , pp. 57-65
    • Hoffman, T.L.1    Doms, R.W.2
  • 20
    • 0033609149 scopus 로고    scopus 로고
    • Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
    • Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW. Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A 1999, 96:5215-5220.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5215-5220
    • Lee, B.1    Sharron, M.2    Montaner, L.J.3    Weissman, D.4    Doms, R.W.5
  • 21
    • 0028046638 scopus 로고
    • Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences
    • Korber BT, Kunstman KJ, Patterson BK, Furtado M, McEvilly MM, Levy R, Wolinsky SM. Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences. J Virol 1994, 68:7467-7481.
    • (1994) J Virol , vol.68 , pp. 7467-7481
    • Korber, B.T.1    Kunstman, K.J.2    Patterson, B.K.3    Furtado, M.4    McEvilly, M.M.5    Levy, R.6    Wolinsky, S.M.7
  • 22
    • 32844457281 scopus 로고    scopus 로고
    • HIV-1 tropism for the central nervous system: brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor
    • Martín-García J, Cao W, Varela-Rohena A, Plassmeyer ML, González-Scarano F. HIV-1 tropism for the central nervous system: brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor. Virology 2006, 346:169-179.
    • (2006) Virology , vol.346 , pp. 169-179
    • Martín-García, J.1    Cao, W.2    Varela-Rohena, A.3    Plassmeyer, M.L.4    González-Scarano, F.5
  • 23
    • 70450170953 scopus 로고    scopus 로고
    • Structure-function analysis of human immunodeficiency virus type 1 gp120 amino acid mutations associated with resistance to the CCR5 coreceptor antagonist vicriviroc
    • Ogert RA, Ba L, Hou Y, Buontempo C, Qiu P, Duca J, Murgolo N, Buontempo P, Ralston R, Howe JA. Structure-function analysis of human immunodeficiency virus type 1 gp120 amino acid mutations associated with resistance to the CCR5 coreceptor antagonist vicriviroc. J Virol 2009, 83:12151-12163.
    • (2009) J Virol , vol.83 , pp. 12151-12163
    • Ogert, R.A.1    Ba, L.2    Hou, Y.3    Buontempo, C.4    Qiu, P.5    Duca, J.6    Murgolo, N.7    Buontempo, P.8    Ralston, R.9    Howe, J.A.10
  • 25
    • 0032864839 scopus 로고    scopus 로고
    • Expanded tropism of primary human immunodeficiency virus type 1 R5 strains to CD4(+) T-cell lines determined by the capacity to exploit low concentrations of CCR5
    • Dejucq N, Simmons G, Clapham PR. Expanded tropism of primary human immunodeficiency virus type 1 R5 strains to CD4(+) T-cell lines determined by the capacity to exploit low concentrations of CCR5. J Virol 1999, 73:7842-7847.
    • (1999) J Virol , vol.73 , pp. 7842-7847
    • Dejucq, N.1    Simmons, G.2    Clapham, P.R.3
  • 27
    • 64849083122 scopus 로고    scopus 로고
    • Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities
    • Pugach P, Ray N, Klasse PJ, Ketas TJ, Michael E, Doms RW, Lee B, Moore JP. Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities. Virology 2009, 387:296-302.
    • (2009) Virology , vol.387 , pp. 296-302
    • Pugach, P.1    Ray, N.2    Klasse, P.J.3    Ketas, T.J.4    Michael, E.5    Doms, R.W.6    Lee, B.7    Moore, J.P.8
  • 32
    • 65549138868 scopus 로고    scopus 로고
    • How HIV changes its tropism: evolution and adaptation?
    • Mosier DE. How HIV changes its tropism: evolution and adaptation?. Curr Opin HIV AIDS 2009, 4:125-130.
    • (2009) Curr Opin HIV AIDS , vol.4 , pp. 125-130
    • Mosier, D.E.1
  • 34
    • 70350316187 scopus 로고    scopus 로고
    • A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains
    • Johnston SH, Lobritz MA, Nguyen S, Lassen K, Delair S, Posta F, Bryson YJ, Arts EJ, Chou T, Lee B. A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains. J Virol 2009, 83:11016-11026.
    • (2009) J Virol , vol.83 , pp. 11016-11026
    • Johnston, S.H.1    Lobritz, M.A.2    Nguyen, S.3    Lassen, K.4    Delair, S.5    Posta, F.6    Bryson, Y.J.7    Arts, E.J.8    Chou, T.9    Lee, B.10
  • 35
    • 80355145632 scopus 로고    scopus 로고
    • HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry
    • Roche M, Jakobsen MR, Ellett A, Salimiseyedabad H, Jubb B, Westby M, Lee B, Lewin SR, Churchill MJ, Gorry PR. HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry. Retrovirology 2011, 8:89.
    • (2011) Retrovirology , vol.8 , pp. 89
    • Roche, M.1    Jakobsen, M.R.2    Ellett, A.3    Salimiseyedabad, H.4    Jubb, B.5    Westby, M.6    Lee, B.7    Lewin, S.R.8    Churchill, M.J.9    Gorry, P.R.10
  • 36
    • 77953305009 scopus 로고    scopus 로고
    • HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells
    • Pfaff JM, Wilen CB, Harrison JE, Demarest JF, Lee B, Doms RW, Tilton JC. HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells. J Virol 2010, 84:6505-6514.
    • (2010) J Virol , vol.84 , pp. 6505-6514
    • Pfaff, J.M.1    Wilen, C.B.2    Harrison, J.E.3    Demarest, J.F.4    Lee, B.5    Doms, R.W.6    Tilton, J.C.7
  • 37
    • 70350330590 scopus 로고    scopus 로고
    • Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4
    • Agrawal-Gamse C, Lee FH, Haggarty B, Jordan APO, Yi Y, Lee B, Collman RG, Hoxie JA, Doms RW, Laakso MM. Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4. J Virol 2009, 83:11005-11015.
    • (2009) J Virol , vol.83 , pp. 11005-11015
    • Agrawal-Gamse, C.1    Lee, F.H.2    Haggarty, B.3    Jordan, A.P.O.4    Yi, Y.5    Lee, B.6    Collman, R.G.7    Hoxie, J.A.8    Doms, R.W.9    Laakso, M.M.10
  • 39
    • 84870700527 scopus 로고    scopus 로고
    • Affinofile profiling: how efficiency of CD4/CCR5 usage impacts the biological and pathogenic phenotype of HIV
    • Chikere K, Chou T, Gorry PR, Lee B. Affinofile profiling: how efficiency of CD4/CCR5 usage impacts the biological and pathogenic phenotype of HIV. Virology 2013, 435:81-91.
    • (2013) Virology , vol.435 , pp. 81-91
    • Chikere, K.1    Chou, T.2    Gorry, P.R.3    Lee, B.4
  • 40
    • 33847186235 scopus 로고    scopus 로고
    • Rev-dependent lentiviral expression vector
    • Wu Y, Beddall MH, Marsh JW. Rev-dependent lentiviral expression vector. Retrovirology 2007, 4:12.
    • (2007) Retrovirology , vol.4 , pp. 12
    • Wu, Y.1    Beddall, M.H.2    Marsh, J.W.3
  • 41
    • 34447259569 scopus 로고    scopus 로고
    • Rev-dependent indicator T cell line
    • Wu Y, Beddall MH, Marsh JW. Rev-dependent indicator T cell line. Curr HIV Res 2007, 5:394-402.
    • (2007) Curr HIV Res , vol.5 , pp. 394-402
    • Wu, Y.1    Beddall, M.H.2    Marsh, J.W.3
  • 42
    • 0027154014 scopus 로고
    • A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism
    • Boyd MT, Simpson GR, Cann AJ, Johnson MA, Weiss RA. A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism. J Virol 1993, 67:3649-3652.
    • (1993) J Virol , vol.67 , pp. 3649-3652
    • Boyd, M.T.1    Simpson, G.R.2    Cann, A.J.3    Johnson, M.A.4    Weiss, R.A.5
  • 44
    • 0037059049 scopus 로고    scopus 로고
    • Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
    • Reeves JD. Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci U S A 2002, 99:16249-16254.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16249-16254
    • Reeves, J.D.1
  • 45
    • 0032546952 scopus 로고    scopus 로고
    • A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding
    • Rizzuto CD. A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science 1998, 280:1949-1953.
    • (1998) Science , vol.280 , pp. 1949-1953
    • Rizzuto, C.D.1
  • 47
    • 77949384495 scopus 로고    scopus 로고
    • Immunology and the elusive AIDS vaccine
    • Virgin HW, Walker BD. Immunology and the elusive AIDS vaccine. Nature 2010, 464:224-231.
    • (2010) Nature , vol.464 , pp. 224-231
    • Virgin, H.W.1    Walker, B.D.2
  • 48
    • 77949409948 scopus 로고    scopus 로고
    • Targeting early infection to prevent HIV-1 mucosal transmission
    • Haase AT. Targeting early infection to prevent HIV-1 mucosal transmission. Nature 2010, 464:217-223.
    • (2010) Nature , vol.464 , pp. 217-223
    • Haase, A.T.1
  • 49
    • 79251508013 scopus 로고    scopus 로고
    • Selective transmission of R5 HIV-1 variants: where is the gatekeeper?
    • Grivel J-C, Shattock RJ, Margolis LB. Selective transmission of R5 HIV-1 variants: where is the gatekeeper?. J Transl Med 2010, 9:S6.
    • (2010) J Transl Med , vol.9
    • Grivel, J.-C.1    Shattock, R.J.2    Margolis, L.B.3
  • 57
    • 0031042433 scopus 로고    scopus 로고
    • The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
    • Bleul CC, Wu L, Hoxie JA, Springer TA, Mackay CR. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A 1997, 94:1925-1930.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1925-1930
    • Bleul, C.C.1    Wu, L.2    Hoxie, J.A.3    Springer, T.A.4    Mackay, C.R.5
  • 60
    • 0031042577 scopus 로고    scopus 로고
    • Quantitative alterations of the functionally distinct subsets of CD4 and CD8 T lymphocytes in asymptomatic HIV infection: changes in the expression of CD45RO, CD45RA, CD11b, CD38, HLA-DR, and CD25 antigens
    • Benito JM, Zabay JM, Gil J, Bermejo M, Escudero A, Sanchez E, Fernandez-Cruz E. Quantitative alterations of the functionally distinct subsets of CD4 and CD8 T lymphocytes in asymptomatic HIV infection: changes in the expression of CD45RO, CD45RA, CD11b, CD38, HLA-DR, and CD25 antigens. J Acquir Immune Defic Syndr Hum Retrovirol 1997, 14:128-135.
    • (1997) J Acquir Immune Defic Syndr Hum Retrovirol , vol.14 , pp. 128-135
    • Benito, J.M.1    Zabay, J.M.2    Gil, J.3    Bermejo, M.4    Escudero, A.5    Sanchez, E.6    Fernandez-Cruz, E.7
  • 62
    • 0030968495 scopus 로고    scopus 로고
    • Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro
    • Spina CA, Prince HE, Richman DD. Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro. J Clin Invest 1997, 99:1774-1785.
    • (1997) J Clin Invest , vol.99 , pp. 1774-1785
    • Spina, C.A.1    Prince, H.E.2    Richman, D.D.3
  • 65
    • 0038555816 scopus 로고    scopus 로고
    • Increased in vitro cytopathicity of CC chemokine receptor 5-restricted human immunodeficiency virus type 1 primary isolates correlates with a progressive clinical course of infection
    • Kwa D, Vingerhoed J, Boeser B, Schuitemaker H. Increased in vitro cytopathicity of CC chemokine receptor 5-restricted human immunodeficiency virus type 1 primary isolates correlates with a progressive clinical course of infection. J Infect Dis 2003, 187:1397-1403.
    • (2003) J Infect Dis , vol.187 , pp. 1397-1403
    • Kwa, D.1    Vingerhoed, J.2    Boeser, B.3    Schuitemaker, H.4
  • 66
    • 82155197617 scopus 로고    scopus 로고
    • Viral determinants of HIV-1 macrophage tropism
    • Duncan CJA, Sattentau QJ. Viral determinants of HIV-1 macrophage tropism. Viruses 2011, 3:2255-2279.
    • (2011) Viruses , vol.3 , pp. 2255-2279
    • Duncan, C.J.A.1    Sattentau, Q.J.2
  • 73
    • 67749118313 scopus 로고    scopus 로고
    • Heterosexual transmission of human immunodeficiency virus type 1 subtype C: Macrophage tropism, alternative coreceptor use, and the molecular anatomy of CCR5 utilization
    • Isaacman-Beck J, Hermann EA, Yi Y, Ratcliffe SJ, Mulenga J, Allen S, Hunter E, Derdeyn CA, Collman RG. Heterosexual transmission of human immunodeficiency virus type 1 subtype C: Macrophage tropism, alternative coreceptor use, and the molecular anatomy of CCR5 utilization. J Virol 2009, 83:8208-8220.
    • (2009) J Virol , vol.83 , pp. 8208-8220
    • Isaacman-Beck, J.1    Hermann, E.A.2    Yi, Y.3    Ratcliffe, S.J.4    Mulenga, J.5    Allen, S.6    Hunter, E.7    Derdeyn, C.A.8    Collman, R.G.9
  • 74
    • 77950493667 scopus 로고    scopus 로고
    • Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry
    • Alexander M, Lynch R, Mulenga J, Allen S, Derdeyn CA, Hunter E. Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry. J Virol 2010, 84:4100-4104.
    • (2010) J Virol , vol.84 , pp. 4100-4104
    • Alexander, M.1    Lynch, R.2    Mulenga, J.3    Allen, S.4    Derdeyn, C.A.5    Hunter, E.6
  • 79
    • 84865303160 scopus 로고    scopus 로고
    • Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12
    • Sterjovski J, Churchill MJ, Ellett A, Wesselingh SL, Ramsland PA, Gorry PR. Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12. Virology 2012, 432:394-404.
    • (2012) Virology , vol.432 , pp. 394-404
    • Sterjovski, J.1    Churchill, M.J.2    Ellett, A.3    Wesselingh, S.L.4    Ramsland, P.A.5    Gorry, P.R.6
  • 82
    • 79961205651 scopus 로고    scopus 로고
    • Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors
    • Berro R, Klasse PJ, Lascano D, Flegler A, Nagashima KA, Sanders RW, Sakmar TP, Hope TJ, Moore JP. Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors. J Virol 2011, 85:8227-8240.
    • (2011) J Virol , vol.85 , pp. 8227-8240
    • Berro, R.1    Klasse, P.J.2    Lascano, D.3    Flegler, A.4    Nagashima, K.A.5    Sanders, R.W.6    Sakmar, T.P.7    Hope, T.J.8    Moore, J.P.9
  • 83
    • 80054804698 scopus 로고    scopus 로고
    • Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach
    • Thiele S, Steen A, Jensen PC, Mokrosinski J, Frimurer TM, Rosenkilde MM. Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach. J Biol Chem 2011, 286:37543-37554.
    • (2011) J Biol Chem , vol.286 , pp. 37543-37554
    • Thiele, S.1    Steen, A.2    Jensen, P.C.3    Mokrosinski, J.4    Frimurer, T.M.5    Rosenkilde, M.M.6
  • 85
    • 84893171838 scopus 로고    scopus 로고
    • Preferential recognition of monomeric CCR5 expressed in cultured cells by the HIV-1 envelope glycoprotein gp120 for the entry of R5 HIV-1
    • Nakano Y, Monde K, Terasawa H, Yuan Y, Yusa K, Harada S, Maeda Y. Preferential recognition of monomeric CCR5 expressed in cultured cells by the HIV-1 envelope glycoprotein gp120 for the entry of R5 HIV-1. Virology 2014, 452-453:117-124.
    • (2014) Virology , vol.452-453 , pp. 117-124
    • Nakano, Y.1    Monde, K.2    Terasawa, H.3    Yuan, Y.4    Yusa, K.5    Harada, S.6    Maeda, Y.7
  • 86
    • 81855208925 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 biological variation and coreceptor use: From concept to clinical significance
    • Fenyö EM, Esbjörnsson J, Medstrand P, Jansson M. Human immunodeficiency virus type 1 biological variation and coreceptor use: From concept to clinical significance. J Intern Med 2011, 270:520-531.
    • (2011) J Intern Med , vol.270 , pp. 520-531
    • Fenyö, E.M.1    Esbjörnsson, J.2    Medstrand, P.3    Jansson, M.4
  • 87
    • 84896539438 scopus 로고    scopus 로고
    • CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association
    • Flegler AJ, Cianci GC, Hope TJ. CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association. PLoS One 2014, 9:e89056.
    • (2014) PLoS One , vol.9
    • Flegler, A.J.1    Cianci, G.C.2    Hope, T.J.3
  • 88
    • 34249889344 scopus 로고    scopus 로고
    • Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands
    • Ketas TJ, Kuhmann SE, Palmer A, Zurita J, He W, Ahuja SK, Klasse PJ, Moore JP. Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands. Virology 2007, 364:281-290.
    • (2007) Virology , vol.364 , pp. 281-290
    • Ketas, T.J.1    Kuhmann, S.E.2    Palmer, A.3    Zurita, J.4    He, W.5    Ahuja, S.K.6    Klasse, P.J.7    Moore, J.P.8
  • 89
    • 34848915403 scopus 로고    scopus 로고
    • The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment
    • Melikyan GB, Platt EJ, Kabat D. The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment. Retrovirology 2007, 4:55.
    • (2007) Retrovirology , vol.4 , pp. 55
    • Melikyan, G.B.1    Platt, E.J.2    Kabat, D.3
  • 93
    • 4143100219 scopus 로고    scopus 로고
    • Preferential in-utero transmission of HIV-1 subtype C as compared to HIV-1 subtype A or D
    • Renjifo B, Gilbert P, Chaplin B, Msamanga G, Mwakagile D, Fawzi W, Essex M. Preferential in-utero transmission of HIV-1 subtype C as compared to HIV-1 subtype A or D. AIDS 2004, 18:1629-1636.
    • (2004) AIDS , vol.18 , pp. 1629-1636
    • Renjifo, B.1    Gilbert, P.2    Chaplin, B.3    Msamanga, G.4    Mwakagile, D.5    Fawzi, W.6    Essex, M.7
  • 94
    • 66149154716 scopus 로고    scopus 로고
    • CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemic
    • Abraha A, Nankya IL, Gibson R, Demers K, Tebit DM, Johnston E, Katzenstein D, Siddiqui A, Herrera C, Fischetti L, Shattock RJ, Arts EJ. CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemic. J Virol 2009, 83:5592-5605.
    • (2009) J Virol , vol.83 , pp. 5592-5605
    • Abraha, A.1    Nankya, I.L.2    Gibson, R.3    Demers, K.4    Tebit, D.M.5    Johnston, E.6    Katzenstein, D.7    Siddiqui, A.8    Herrera, C.9    Fischetti, L.10    Shattock, R.J.11    Arts, E.J.12
  • 96
    • 18844372793 scopus 로고    scopus 로고
    • Differences in the fitness of Two diverse wild-type human immunodeficiency virus type 1 isolates Are related to the efficiency of cell binding and entry
    • Marozsan AJ, Moore DM, Lobritz MA, Fraundorf E, Abraha A, Reeves JD, Arts EJ. Differences in the fitness of Two diverse wild-type human immunodeficiency virus type 1 isolates Are related to the efficiency of cell binding and entry. J Virol 2005, 79:7121-7134.
    • (2005) J Virol , vol.79 , pp. 7121-7134
    • Marozsan, A.J.1    Moore, D.M.2    Lobritz, M.A.3    Fraundorf, E.4    Abraha, A.5    Reeves, J.D.6    Arts, E.J.7
  • 97
    • 0344766077 scopus 로고    scopus 로고
    • Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage
    • Morner A, Bjorndal A, Albert J, Kewalramani VN, Littman DR, Inoue R, Thorstensson R, Fenyo EM, Bjorling E. Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage. J Virol 1999, 73:2343-2349.
    • (1999) J Virol , vol.73 , pp. 2343-2349
    • Morner, A.1    Bjorndal, A.2    Albert, J.3    Kewalramani, V.N.4    Littman, D.R.5    Inoue, R.6    Thorstensson, R.7    Fenyo, E.M.8    Bjorling, E.9


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