Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy

PLoS Pathogens

Volumn 8, Issue 1, 2012, Pages

  Zeng, Ming ^a   Southern, Peter J ^a   Reilly, Cavan S ^b   Beilman, Greg J ^a   Chipman, Jeffrey G ^a   Schacker, Timothy W ^a   Haase, Ashley T ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; COLLAGEN; DESMIN; INTERLEUKIN 7; KI 67 ANTIGEN; MACROPHAGE INFLAMMATORY PROTEIN 3BETA;

ADULT; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL POPULATION; CELL SURVIVAL; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE SYSTEM; IN VIVO STUDY; LYMPH NODE BIOPSY; LYMPHOID TISSUE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PROTEIN LOCALIZATION; RETICULUM CELL; T CELL DEPLETION; TISSUE INJURY; TREATMENT DURATION; VIRUS LOAD; VIRUS REPLICATION;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; FEMALE; FIBROSIS; HIV INFECTIONS; HIV-1; HUMANS; INTERLEUKIN-7; LYMPHOID TISSUE; MALE; MIDDLE AGED; TIME FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84857479601     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002437     Document Type: Article

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