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Volumn 20, Issue , 2014, Pages 1003-1016

Age-related macular degeneration and changes in the extracellular matrix

Author keywords

AMD; Bruch's membrane; Collagen; Elastin; Extracellular matrix; Metalloproteinases; Tissue inhibitors of metalloproteinases

Indexed keywords

COLLAGEN; COLLAGEN TYPE 4; COMPLEMENT MEMBRANE ATTACK COMPLEX; DOCOSAHEXAENOIC ACID; ELASTIN; ENTACTIN; FIBULIN; HEPARAN SULFATE; HYPOXIA INDUCIBLE FACTOR 1; LAMININ; MATRIX METALLOPROTEINASE; SERINE PROTEINASE OMI; TISSUE INHIBITOR OF METALLOPROTEINASE; UROKINASE RECEPTOR; VASCULOTROPIN;

EID: 84902577141     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.889887     Document Type: Review
Times cited : (96)

References (204)
  • 1
    • 0035500490 scopus 로고    scopus 로고
    • The many faces of metalloproteinases: Cell growth, invasion, angiogenesis and metastasis
    • Chang C, Werb Z: The many faces of metalloproteinases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol, 2001; 11: 37-43
    • (2001) Trends Cell Biol , vol.11 , pp. 37-43
    • Chang, C.1    Werb, Z.2
  • 2
    • 31344458952 scopus 로고    scopus 로고
    • Structure and function of matrix metalloproteinases and TIMPs
    • Nagase H, Visse R, Murphy G: Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res, 2006; 69: 562-73
    • (2006) Cardiovasc Res , vol.69 , pp. 562-573
    • Nagase, H.1    Visse, R.2    Murphy, G.3
  • 3
    • 0033618337 scopus 로고    scopus 로고
    • Matrix Metalloproteinases
    • Nagase H, Woessner JF: Matrix Metalloproteinases. J Biol Chem, 1999;274(31): 21491-94
    • (1999) J Biol Chem , vol.274 , Issue.31 , pp. 21491-21494
    • Nagase, H.1    Woessner, J.F.2
  • 4
    • 0031719049 scopus 로고    scopus 로고
    • Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes
    • Steen B, Sejersen S, Berglin L et al: Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes. Invest Ophthalmol Vis Sci, 1998; 39: 2194-200
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 2194-2200
    • Steen, B.1    Sejersen, S.2    Berglin, L.3
  • 5
    • 0037693895 scopus 로고    scopus 로고
    • Matrix Metaloproteinases and tissue inhibitors of metaloproteinases
    • Visse R, Nagase H: Matrix Metaloproteinases and tissue inhibitors of metaloproteinases. Circ Res, 2003; 92: 827-39
    • (2003) Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 6
    • 0025744976 scopus 로고
    • Transforming growth factor beta stimulates the production of the tissue inhibitor of metalloproteinases (TIMP) by human synovial and skin fibroblasts
    • Wright JK, Cawston TE, Hazleman BL: Transforming growth factor beta stimulates the production of the tissue inhibitor of metalloproteinases (TIMP) by human synovial and skin fibroblasts. Biochim Biophys Acta, 1991; 1094: 207-10
    • (1991) Biochim Biophys Acta , vol.1094 , pp. 207-210
    • Wright, J.K.1    Cawston, T.E.2    Hazleman, B.L.3
  • 7
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta L, Steeg PS, Stetler-Stevenson WG: Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell, 1991; 64: 327-36
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 9
    • 75749140621 scopus 로고    scopus 로고
    • ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations
    • Kortvely E, Hauck SM, Duetach G et al: ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations. Invest Ophtalmol Vis Sci, 2010; 51(1): 79-89
    • (2010) Invest Ophtalmol Vis Sci , vol.51 , Issue.1 , pp. 79-89
    • Kortvely, E.1    Hauck, S.M.2    Duetach, G.3
  • 10
    • 0028025373 scopus 로고
    • Expression of TIMP3 mRNA is elevated in retinas affected by simplex retinitis pigmentosa
    • Jones SE, Jomary C, Neal MJ: Expression of TIMP3 mRNA is elevated in retinas affected by simplex retinitis pigmentosa. Feder Euro Bioch Soc Letters, 1994; 352: 171-74
    • (1994) Feder Euro Bioch Soc Letters , vol.352 , pp. 171-174
    • Jones, S.E.1    Jomary, C.2    Neal, M.J.3
  • 11
    • 0036154168 scopus 로고    scopus 로고
    • Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinaseinhibitory activities, but affect cell adhesion to the extracellular matrix
    • Yeow KM, Kishnani NS, Hutton M et al: Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinaseinhibitory activities, but affect cell adhesion to the extracellular matrix. Matrix Biol, 2002; 21: 75-88
    • (2002) Matrix Biol , vol.21 , pp. 75-88
    • Yeow, K.M.1    Kishnani, N.S.2    Hutton, M.3
  • 12
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • De Jong PT: Age-related macular degeneration. N Engl J Med, 2006; 355: 1474-85
    • (2006) N Engl J Med , vol.355 , pp. 1474-1485
    • De Jong, P.T.1
  • 13
    • 33749132608 scopus 로고    scopus 로고
    • Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo
    • Marin-Castaño ME, Striker GE, Alcazar O et al: Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo. Invest Ophthalmol Vis Sci, 2006; 47: 4098-112
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 4098-4112
    • Marin-Castaño, M.E.1    Striker, G.E.2    Alcazar, O.3
  • 14
    • 1842478123 scopus 로고    scopus 로고
    • Current concepts in the pathogenesis of age-related macular degeneration
    • Zarbin MA: Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol, 2004; 122(4): 598-614
    • (2004) Arch Ophthalmol , vol.122 , Issue.4 , pp. 598-614
    • Zarbin, M.A.1
  • 15
    • 0037403180 scopus 로고    scopus 로고
    • Human RPE cell lysis of extracellular matrix: Functional urokinase plasminogen activator receptor (uPAR), collagenase and elastase
    • Elner SG, Elner VM, Kindzelskii AL et al: Human RPE cell lysis of extracellular matrix: functional urokinase plasminogen activator receptor (uPAR), collagenase and elastase. Exp Eye Res, 2003; 76: 585-95
    • (2003) Exp Eye Res , vol.76 , pp. 585-595
    • Elner, S.G.1    Elner, V.M.2    Kindzelskii, A.L.3
  • 17
    • 33644788693 scopus 로고    scopus 로고
    • Bruch's membrane and the vascular intima: Is there a common basis for age-related changes and disease?
    • Sivaprasad S, Bailey TA, Chong VNH: Bruch's membrane and the vascular intima: is there a common basis for age-related changes and disease?. Clin Exp Ophthalmol, 2005; 33: 518-23
    • (2005) Clin Exp Ophthalmol , vol.33 , pp. 518-523
    • Sivaprasad, S.1    Bailey, T.A.2    Chong, V.N.H.3
  • 18
    • 0034934098 scopus 로고    scopus 로고
    • Unilateral or asymetric pseudoexfoliation syndrome? An ultrastructural study
    • Hammer TH, Schlotzer-Schrehardt U, Naumann G: Unilateral or asymetric pseudoexfoliation syndrome? An ultrastructural study. Arch Ophthalmol, 2001; 119(7): 1023-31
    • (2001) Arch Ophthalmol , vol.119 , Issue.7 , pp. 1023-1031
    • Hammer, T.H.1    Schlotzer-Schrehardt, U.2    Naumann, G.3
  • 21
    • 0029073646 scopus 로고
    • Detection of proteoglycans in human posterior capsule opacification
    • Ishibashi T, Araki H, Sugai S et al: Detection of proteoglycans in human posterior capsule opacification. Ophthalmic Res, 1995; 27: 208-13
    • (1995) Ophthalmic Res , vol.27 , pp. 208-213
    • Ishibashi, T.1    Araki, H.2    Sugai, S.3
  • 22
    • 0027967798 scopus 로고
    • Collagen types in human posterior capsule opacification
    • Ishibashi T, Hatae T, Inomata H: Collagen types in human posterior capsule opacification. J Cataract Refract Surg, 1994; 20: 643-46
    • (1994) J Cataract Refract Surg , vol.20 , pp. 643-646
    • Ishibashi, T.1    Hatae, T.2    Inomata, H.3
  • 23
    • 0030043897 scopus 로고    scopus 로고
    • Effects of the cytokines on the proliferation of and collagen synthesis by human cataract lens epithelial cells
    • Nishi O, Nishi K, Fujiwara T et al: Effects of the cytokines on the proliferation of and collagen synthesis by human cataract lens epithelial cells. Br J Ophthalmol, 1996; 80: 63-68
    • (1996) Br J Ophthalmol , vol.80 , pp. 63-68
    • Nishi, O.1    Nishi, K.2    Fujiwara, T.3
  • 24
    • 0032033167 scopus 로고    scopus 로고
    • Immunolocalization of prolyl 4 hydroxylase subunits, a-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants
    • Saika S, Kawashima Y, Miyamoto T et al: Immunolocalization of prolyl 4 hydroxylase subunits, a-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants. Exp Eye Res, 1998a; 66: 283-94
    • (1998) Exp Eye Res , vol.66 , pp. 283-294
    • Saika, S.1    Kawashima, Y.2    Miyamoto, T.3
  • 25
    • 0031793281 scopus 로고    scopus 로고
    • Immunohistochemical identification of proteoglycan types in fibrotic human capsules with intraocular lens implants
    • Saika S, Kawashima Y, Miyamoto T et al: Immunohistochemical identification of proteoglycan types in fibrotic human capsules with intraocular lens implants. Jpn J Ophthalmol, 1998b; 42: 368-72
    • (1998) Jpn J Ophthalmol , vol.42 , pp. 368-372
    • Saika, S.1    Kawashima, Y.2    Miyamoto, T.3
  • 26
    • 79960731769 scopus 로고    scopus 로고
    • High glucose-induced altered basement membrane composition and structure increases trans-endothelial permeability: Implications for diabetic retinopathy
    • Chronopoulos A, Trudeau K, Roy S et al: High glucose-induced altered basement membrane composition and structure increases trans-endothelial permeability: implications for diabetic retinopathy. Curr Eye Res, 2011; 36(8): 747-53
    • (2011) Curr Eye Res , vol.36 , Issue.8 , pp. 747-753
    • Chronopoulos, A.1    Trudeau, K.2    Roy, S.3
  • 27
    • 9444269815 scopus 로고    scopus 로고
    • Pharmacotherapy for diabetic retinopathy
    • Comer GM, Ciulla TA: Pharmacotherapy for diabetic retinopathy Curr Opin Ophthalmol, 2004; 15(6): 508-18
    • (2004) Curr Opin Ophthalmol , vol.15 , Issue.6 , pp. 508-518
    • Comer, G.M.1    Ciulla, T.A.2
  • 28
    • 0027501402 scopus 로고
    • Epiretinal membrane of proliferative diabetic retinopathy: An immunohistochemical study
    • Hosoda Y, Okada M, Matsumura M et al: Epiretinal membrane of proliferative diabetic retinopathy: an immunohistochemical study. Ophthalmic Res, 1993; 25(5): 289-94
    • (1993) Ophthalmic Res , vol.25 , Issue.5 , pp. 289-294
    • Hosoda, Y.1    Okada, M.2    Matsumura, M.3
  • 30
    • 1542297335 scopus 로고    scopus 로고
    • The epidemiology of age-related macular degeneration
    • Klein R, Peto T, Bird A, Vannewkirk MR: The epidemiology of age-related macular degeneration. Am J Ophthalmol, 2004; 137: 486-95
    • (2004) Am J Ophthalmol , vol.137 , pp. 486-495
    • Klein, R.1    Peto, T.2    Bird, A.3    Vannewkirk, M.R.4
  • 31
    • 0035128064 scopus 로고    scopus 로고
    • Risk factors for age-related macular degeneration
    • Evans JR: Risk factors for age-related macular degeneration. Prog Retin Eye Res, 2001; 20: 227-53
    • (2001) Prog Retin Eye Res , vol.20 , pp. 227-253
    • Evans, J.R.1
  • 32
    • 0034800657 scopus 로고    scopus 로고
    • Risk factors for age-related maculopathy: The Visual Impairment Project
    • McCarty CA, Mukesh BN, Fu CL et al: Risk factors for age-related maculopathy: the Visual Impairment Project. Arch Ophthalmol, 2001; 119: 1455-62
    • (2001) Arch Ophthalmol , vol.119 , pp. 1455-1462
    • McCarty, C.A.1    Mukesh, B.N.2    Fu, C.L.3
  • 33
    • 26844516051 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • McConnell V, Silvestri G: Age-related macular degeneration. Ulster Med J, 2005; 74: 82-92
    • (2005) Ulster Med J , vol.74 , pp. 82-92
    • McConnell, V.1    Silvestri, G.2
  • 34
    • 0035078715 scopus 로고    scopus 로고
    • Risk factors for age-related macular degeneration: Pooled findings from three continents
    • Smith W, Assink J, Klein R et al: Risk factors for age-related macular degeneration: pooled findings from three continents. Ophthalmology, 2001; 108: 697-704
    • (2001) Ophthalmology , vol.108 , pp. 697-704
    • Smith, W.1    Assink, J.2    Klein, R.3
  • 35
    • 70749131890 scopus 로고    scopus 로고
    • Estrogen receptor b protects against in vivo injury in RPE cells
    • Elliot SJ, Catanuto P, Espinosa-Heidmann DG et al: Estrogen receptor b protects against in vivo injury in RPE cells. Exp Eye Res, 2010; 90: 10-16
    • (2010) Exp Eye Res , vol.90 , pp. 10-16
    • Elliot, S.J.1    Catanuto, P.2    Espinosa-Heidmann, D.G.3
  • 36
    • 71049145998 scopus 로고    scopus 로고
    • Proteomics Characterization of cell membrane blebs in human retinal pigment epithelium cells
    • Alcazar O, Hawkridge AM, Collier TS et al: Proteomics Characterization of cell membrane blebs in human retinal pigment epithelium cells. Mol Cell Proteomics, 2009; 8(10): 2201-11
    • (2009) Mol Cell Proteomics , vol.8 , Issue.10 , pp. 2201-2211
    • Alcazar, O.1    Hawkridge, A.M.2    Collier, T.S.3
  • 37
    • 0033756108 scopus 로고    scopus 로고
    • The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration
    • Friedman E: The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration. Am J Ophthalmol, 2000; 130: 658-63
    • (2000) Am J Ophthalmol , vol.130 , pp. 658-663
    • Friedman, E.1
  • 38
    • 0034102998 scopus 로고    scopus 로고
    • Hypertension, cardiovascular disease, and age-related macular degeneration
    • Hyman L, Schachat AP, He Q, Leske MC: Hypertension, cardiovascular disease, and age-related macular degeneration. Arch Ophthalmol, 2000; 118: 351-58
    • (2000) Arch Ophthalmol , vol.118 , pp. 351-358
    • Hyman, L.1    Schachat, A.P.2    He, Q.3    Leske, M.C.4
  • 39
    • 0037313596 scopus 로고    scopus 로고
    • Influence of arterial hypertension and diet-induced atherosclerosis on macular drusen
    • Jonas JB, Hayreh SS, Martus P: Influence of arterial hypertension and diet-induced atherosclerosis on macular drusen. Graefes Arch Clin Exp Ophthalmol, 2003; 241(2): 125-34
    • (2003) Graefes Arch Clin Exp Ophthalmol , vol.241 , Issue.2 , pp. 125-134
    • Jonas, J.B.1    Hayreh, S.S.2    Martus, P.3
  • 40
    • 0038409910 scopus 로고    scopus 로고
    • The association of cardiovascular disease with the long-term incidence of age-related maculopathy
    • Klein R, Klein BE, Tomany SC, Cruickshanks KJ: The association of cardiovascular disease with the long-term incidence of age-related maculopathy. Ophthalmology, 2003; 110: 1273-80
    • (2003) Ophthalmology , vol.110 , pp. 1273-1280
    • Klein, R.1    Klein, B.E.2    Tomany, S.C.3    Cruickshanks, K.J.4
  • 41
    • 67349098413 scopus 로고    scopus 로고
    • Angiotensin IIinduced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium
    • Praddaude F, Cousins SW, Pêcher C, Marin-Castano ME: Angiotensin IIinduced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium. Exp Eye Res, 2009; 89: 109-18
    • (2009) Exp Eye Res , vol.89 , pp. 109-118
    • Praddaude, F.1    Cousins, S.W.2    Pêcher, C.3    Marin-Castano, M.E.4
  • 42
    • 0032808594 scopus 로고    scopus 로고
    • Do age-related macular degeneration and cardiovascular disease share common antecedents?
    • Snow KK, Seddon JM: Do age-related macular degeneration and cardiovascular disease share common antecedents? Ophthalmic Epidemiol, 1999; 6: 125-43
    • (1999) Ophthalmic Epidemiol , vol.6 , pp. 125-143
    • Snow, K.K.1    Seddon, J.M.2
  • 43
    • 0032529241 scopus 로고
    • Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2
    • Deryugina EI, Bourdon MA, Reisfeld RA, Strongin A: Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2. Cancer Res, 1989; 58: 3743-50
    • (1989) Cancer Res , vol.58 , pp. 3743-3750
    • Deryugina, E.I.1    Bourdon, M.A.2    Reisfeld, R.A.3    Strongin, A.4
  • 44
    • 0031788693 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases and metalloproteinases in atherosclerosis
    • George SJ: Tissue inhibitors of metalloproteinases and metalloproteinases in atherosclerosis Curr Opin Lipidol, 1998; 9: 413-23
    • (1998) Curr Opin Lipidol , vol.9 , pp. 413-423
    • George, S.J.1
  • 45
    • 27244452645 scopus 로고    scopus 로고
    • Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity
    • Marin-Castaño ME, Csaky KG, Cousins SW: Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity. Invest Ophthalmol Vis Sci, 2005; 46: 3331-40
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 3331-3340
    • Marin-Castaño, M.E.1    Csaky, K.G.2    Cousins, S.W.3
  • 46
    • 0025055344 scopus 로고
    • Drusen as risk factors in age-related macular disease
    • Pauleikhoff D, Barondes MJ, Minassian D et al: Drusen as risk factors in age-related macular disease. Am J Ophthalmol, 1990; 109: 38-43
    • (1990) Am J Ophthalmol , vol.109 , pp. 38-43
    • Pauleikhoff, D.1    Barondes, M.J.2    Minassian, D.3
  • 47
    • 0344952154 scopus 로고    scopus 로고
    • The role of glycoproteins and integrins in human RPE-induced collagen matrix contraction
    • Sheridan CM, Hiscott P, Grierson I: The role of glycoproteins and integrins in human RPE-induced collagen matrix contraction. Exp Eye Res, 2000; 71: S119
    • (2000) Exp Eye Res , vol.71
    • Sheridan, C.M.1    Hiscott, P.2    Grierson, I.3
  • 48
    • 0025351859 scopus 로고
    • Occurrence of drusen, pigmentary changes and exudative changes in the macula with reference to age-related macular degeneration An epidemiological study of 1000 aged individuals
    • Vinding T: Occurrence of drusen, pigmentary changes and exudative changes in the macula with reference to age-related macular degeneration An epidemiological study of 1000 aged individuals. Acta Ophthalmol (Copenh), 1990; 68: 410-14
    • (1990) Acta Ophthalmol (Copenh) , vol.68 , pp. 410-414
    • Vinding, T.1
  • 52
    • 67349126182 scopus 로고    scopus 로고
    • Developmental distribution of collagen IV isoforms and relevance to ocular diseases
    • Bai X, Dilworth DJ, Weng Yi-C et al: Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biology, 2009; 28: 194-201
    • (2009) Matrix Biology , vol.28 , pp. 194-201
    • Bai, X.1    Dilworth, D.J.2    Weng, Y.-C.3
  • 53
    • 0024786778 scopus 로고
    • Basement membranes: Molecular organization and function in development and disease
    • Schittny JC, Yurchenco PD: Basement membranes: molecular organization and function in development and disease. Curr Opin Cell Biol, 1989; 1(5): 983-88
    • (1989) Curr Opin Cell Biol , vol.1 , Issue.5 , pp. 983-988
    • Schittny, J.C.1    Yurchenco, P.D.2
  • 54
    • 70349448532 scopus 로고    scopus 로고
    • (Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling
    • Alcazar O, Cousins SW, Striker GE, Marin-Castano ME: (Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling. Exp Eye Res, 2009; 89: 638-47
    • (2009) Exp Eye Res , vol.89 , pp. 638-647
    • Alcazar, O.1    Cousins, S.W.2    Striker, G.E.3    Marin-Castano, M.E.4
  • 55
    • 0030957218 scopus 로고    scopus 로고
    • Activation mechanism of matrix metalloproteinases
    • Nagasse H: Activation mechanism of matrix metalloproteinases. Biol Chem, 1997; 378: 151-60
    • (1997) Biol Chem , vol.378 , pp. 151-160
    • Nagasse, H.1
  • 56
    • 0033230113 scopus 로고    scopus 로고
    • Membrane associated matrix metalloproteinases in metastasis
    • Ellerbroek SM, Stack SM: Membrane associated matrix metalloproteinases in metastasis Bioessays, 1999; 21: 940-49
    • (1999) Bioessays , vol.21 , pp. 940-949
    • Ellerbroek, S.M.1    Stack, S.M.2
  • 57
    • 0037309778 scopus 로고    scopus 로고
    • Distribution of the collagen IVisoforms in human Bruch's membrane
    • Chen L, Miyamura N, Ninomiya Y, Handa JT: Distribution of the collagen IVisoforms in human Bruch's membrane. Br J Ophthalmol, 2003; 87(2): 212-15
    • (2003) Br J Ophthalmol , vol.87 , Issue.2 , pp. 212-215
    • Chen, L.1    Miyamura, N.2    Ninomiya, Y.3    Handa, J.T.4
  • 58
    • 0025319722 scopus 로고
    • Ultrastructural localization of extracellular matrix components in human retinal vessels and Bruch's membrane
    • Das A, Frank RN, Zhang NL, Turczyn TJ: Ultrastructural localization of extracellular matrix components in human retinal vessels and Bruch's membrane. Arch Ophthalmol, 1990; 108(3): 421-29
    • (1990) Arch Ophthalmol , vol.108 , Issue.3 , pp. 421-429
    • Das, A.1    Frank, R.N.2    Zhang, N.L.3    Turczyn, T.J.4
  • 59
    • 0033808066 scopus 로고    scopus 로고
    • Still more complexity in mammalian basement membranes
    • Erickson AC, Couchman JR: Still more complexity in mammalian basement membranes. J Histochem Cytochem, 2000; 48(10): 1291-306
    • (2000) J Histochem Cytochem , vol.48 , Issue.10 , pp. 1291-1306
    • Erickson, A.C.1    Couchman, J.R.2
  • 60
    • 34447336145 scopus 로고    scopus 로고
    • Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis
    • Gould DB, Marchant JK, Savinova OV et al: Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis. Hum Mol Genet, 2007; 16(7): 798-807
    • (2007) Hum Mol Genet , vol.16 , Issue.7 , pp. 798-807
    • Gould, D.B.1    Marchant, J.K.2    Savinova, O.V.3
  • 61
    • 34247866422 scopus 로고    scopus 로고
    • Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus musculus: An extension of the Col4a1 allelic series and the identification of the first two Col4a2 mutant alleles
    • Favor J, Gloeckner CJ, Janik D et al: Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus musculus: an extension of the Col4a1 allelic series and the identification of the first two Col4a2 mutant alleles. Genetics, 2007; 175: 725-36
    • (2007) Genetics , vol.175 , pp. 725-736
    • Favor, J.1    Gloeckner, C.J.2    Janik, D.3
  • 62
    • 79551505872 scopus 로고    scopus 로고
    • Mapping structural landmarks, ligand binding sites, and missense mutations to the Collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes
    • Parkin JD, San Antonio JD, Pedchenko V et al: Mapping structural landmarks, ligand binding sites, and missense mutations to the Collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes. Hum Mutation, 2011; 32(2): 127-43
    • (2011) Hum Mutation , vol.32 , Issue.2 , pp. 127-143
    • Parkin, J.D.1    San Antonio, J.D.2    Pedchenko, V.3
  • 64
    • 1842482987 scopus 로고    scopus 로고
    • Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development
    • Poschl E, Schlotzer-Schrehardt U, Brachvogel B et al: Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development, 2004; 131: 1619-28
    • (2004) Development , vol.131 , pp. 1619-1628
    • Poschl, E.1    Schlotzer-Schrehardt, U.2    Brachvogel, B.3
  • 65
    • 0031729936 scopus 로고    scopus 로고
    • Laminin isoforms and epithelial development
    • Ekblom M, Falk M, Salmivirta K et al: Laminin isoforms and epithelial development. Ann NY Acad Sci, 1998; 23(857): 194-211
    • (1998) Ann NY Acad Sci , vol.23 , Issue.857 , pp. 194-211
    • Ekblom, M.1    Falk, M.2    Salmivirta, K.3
  • 66
    • 0026705606 scopus 로고
    • Type IV collagen and laminin in Bruch's membrane and basal linear deposit in the human macula
    • Marshall GE, Konstas AG, Reid GG et al: Type IV collagen and laminin in Bruch's membrane and basal linear deposit in the human macula. Br J Ophthalmol, 1992; 76: 607-14
    • (1992) Br J Ophthalmol , vol.76 , pp. 607-614
    • Marshall, G.E.1    Konstas, A.G.2    Reid, G.G.3
  • 67
    • 0037113093 scopus 로고    scopus 로고
    • New functional roles for non-collagenous domains of basement membrane collagens
    • Ortega N, Werb Z: New functional roles for non-collagenous domains of basement membrane collagens. J Cell Sci, 2002; 115: 4201-14
    • (2002) J Cell Sci , vol.115 , pp. 4201-4214
    • Ortega, N.1    Werb, Z.2
  • 68
    • 77950643073 scopus 로고    scopus 로고
    • Role of COL4A1 in basement-membrane integrity and cerebral small-vessel disease. The COL4A1 Stroke Syndrome
    • Volonghi I, Pezzini A, del Zotto E et al: Role of COL4A1 in basement-membrane integrity and cerebral small-vessel disease. The COL4A1 Stroke Syndrome. Curr Med Chem, 2010; 17(13): 1317-24
    • (2010) Curr Med Chem , vol.17 , Issue.13 , pp. 1317-1324
    • Volonghi, I.1    Pezzini, A.2    del Zotto, E.3
  • 69
    • 42949086409 scopus 로고    scopus 로고
    • Laminins and their roles in mammals
    • Miner JH: Laminins and their roles in mammals. Microsc Res Tech, 2008; 71: 349-56
    • (2008) Microsc Res Tech , vol.71 , pp. 349-356
    • Miner, J.H.1
  • 70
    • 0033545239 scopus 로고    scopus 로고
    • Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation
    • Smyth N, Vatansever HS, Murray P et al: Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation. J Cell Biol, 1999; 144: 151-60
    • (1999) J Cell Biol , vol.144 , pp. 151-160
    • Smyth, N.1    Vatansever, H.S.2    Murray, P.3
  • 71
    • 34547093441 scopus 로고    scopus 로고
    • Role of laminin terminal globular domains in basement membrane assembly
    • McKee KK, Harrison D, Capizzi S, Yurchenco PD: Role of laminin terminal globular domains in basement membrane assembly. J Biol Chem, 2007; 282: 21437-47
    • (2007) J Biol Chem , vol.282 , pp. 21437-21447
    • McKee, K.K.1    Harrison, D.2    Capizzi, S.3    Yurchenco, P.D.4
  • 72
    • 22544456862 scopus 로고    scopus 로고
    • Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice
    • Bader BL, Smyth N, Nedbal S et al: Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice. Mol Cell Biol, 2005; 25: 6846-56
    • (2005) Mol Cell Biol , vol.25 , pp. 6846-6856
    • Bader, B.L.1    Smyth, N.2    Nedbal, S.3
  • 73
    • 0031820133 scopus 로고    scopus 로고
    • Entactin-2: A new member of basement membrane proteins with high homology to entactin/ nidogen
    • Kimura N, Toyoshima T, Kojima T, Shimane M: Entactin-2: a new member of basement membrane proteins with high homology to entactin/ nidogen. Exp Cell Res, 1998; 241: 36-45
    • (1998) Exp Cell Res , vol.241 , pp. 36-45
    • Kimura, N.1    Toyoshima, T.2    Kojima, T.3    Shimane, M.4
  • 74
    • 0032508461 scopus 로고    scopus 로고
    • Nidogen-2: A new basement membrane protein with diverse binding properties
    • Kohfeldt E, Sasaki T, Gohring W, Timpl R: Nidogen-2: a new basement membrane protein with diverse binding properties. J Mol Biol, 1998; 282: 99-109
    • (1998) J Mol Biol , vol.282 , pp. 99-109
    • Kohfeldt, E.1    Sasaki, T.2    Gohring, W.3    Timpl, R.4
  • 75
    • 0025333863 scopus 로고
    • The basement membrane glycoprotein entactin promotes cell attachment and binds calcium ions
    • Chakravarti S, Tam MF, Chung AE: The basement membrane glycoprotein entactin promotes cell attachment and binds calcium ions. J Biol Chem, 1990; 265: 10597-603
    • (1990) J Biol Chem , vol.265 , pp. 10597-10603
    • Chakravarti, S.1    Tam, M.F.2    Chung, A.E.3
  • 76
    • 0030056968 scopus 로고    scopus 로고
    • Cell adhesion: The molecular basis of tissue architecture and morphogenesis
    • Gumbiner B: Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell, 1996; 84: 345-57
    • (1996) Cell , vol.84 , pp. 345-357
    • Gumbiner, B.1
  • 77
    • 0032126693 scopus 로고    scopus 로고
    • Mapping of thebinding of platelet derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope
    • Gohring W, Sasaki T, Heldin CH, Timpl R: Mapping of thebinding of platelet derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope. Eur J Biochem, 1998; 255: 60-66
    • (1998) Eur J Biochem , vol.255 , pp. 60-66
    • Gohring, W.1    Sasaki, T.2    Heldin, C.H.3    Timpl, R.4
  • 78
    • 0024599081 scopus 로고
    • Analysis of newly synthesized Bruch's membrane proteoglycans
    • Hewitt AT, Nakazawa K, Newsome DA: Analysis of newly synthesized Bruch's membrane proteoglycans. Invest Ophthalmol Vis Sci, 1989; 30(3): 478-86
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , Issue.3 , pp. 478-486
    • Hewitt, A.T.1    Nakazawa, K.2    Newsome, D.A.3
  • 79
    • 0031657808 scopus 로고    scopus 로고
    • Matrix proteoglycans: From molecular design to cellular function
    • Iozzo RV: Matrix proteoglycans: from molecular design to cellular function. Annu Rev Biochem, 1998; 67: 609-52
    • (1998) Annu Rev Biochem , vol.67 , pp. 609-652
    • Iozzo, R.V.1
  • 80
    • 0022525896 scopus 로고
    • Antibodies to basement membrane heparan sulfate proteoglycans bind to thelaminae rarae of the glomerular basement membrane (GBM) and induce subepithelial GBM thickening
    • Miettinen A, Stow JL, Mentone S, Farquhar MG: Antibodies to basement membrane heparan sulfate proteoglycans bind to thelaminae rarae of the glomerular basement membrane (GBM) and induce subepithelial GBM thickening. J Exp Med, 1986; 163: 1064-84
    • (1986) J Exp Med , vol.163 , pp. 1064-1084
    • Miettinen, A.1    Stow, J.L.2    Mentone, S.3    Farquhar, M.G.4
  • 81
    • 0032889433 scopus 로고    scopus 로고
    • Changes in Bruch's membrane and related structures with age
    • Guymer R, Luthert P, Bird A: Changes in Bruch's membrane and related structures with age. Prog Retin Eye Res, 1999; 18: 59-90
    • (1999) Prog Retin Eye Res , vol.18 , pp. 59-90
    • Guymer, R.1    Luthert, P.2    Bird, A.3
  • 82
    • 68949144886 scopus 로고    scopus 로고
    • Molecular and mesoscale mechanisms of osteogenesis imperfecta disease in collagen fibrils
    • Gautieri A, Uzel S, Vesentini S et al: Molecular and mesoscale mechanisms of osteogenesis imperfecta disease in collagen fibrils. Biophysical J, 2009; 97: 857-65
    • (2009) Biophysical J , vol.97 , pp. 857-865
    • Gautieri, A.1    Uzel, S.2    Vesentini, S.3
  • 83
    • 33847227672 scopus 로고    scopus 로고
    • Consortium for osteogenesis imperfecta mutations in the helical domain of type I collagen: Regions rich in lethal mutations align with collagen binding sites for integrins and proteoglycans
    • Marini JC, Forlino A, Cabral WA et al: Consortium for osteogenesis imperfecta mutations in the helical domain of type I collagen: regions rich in lethal mutations align with collagen binding sites for integrins and proteoglycans. Hum Mutat, 2007; 28: 209-21
    • (2007) Hum Mutat , vol.28 , pp. 209-221
    • Marini, J.C.1    Forlino, A.2    Cabral, W.A.3
  • 84
    • 51049121850 scopus 로고    scopus 로고
    • Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates
    • Sweeney SM, Orgel JP, Fertala A et al: Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates. J Biol Chem, 2008; 283: 21187-97
    • (2008) J Biol Chem , vol.283 , pp. 21187-21197
    • Sweeney, S.M.1    Orgel, J.P.2    Fertala, A.3
  • 85
    • 35648987246 scopus 로고    scopus 로고
    • The upregulation of angiogenic gene expression in cultured retinal pigment epithelial cells grown on type I collagen
    • Imai H, Honda S, Kondo N et al: The upregulation of angiogenic gene expression in cultured retinal pigment epithelial cells grown on type I collagen. Curr Eye Res, 2007; 32: 903-10
    • (2007) Curr Eye Res , vol.32 , pp. 903-910
    • Imai, H.1    Honda, S.2    Kondo, N.3
  • 86
    • 0025089876 scopus 로고
    • Factors affecting the migration and growth of endothelial cells from icrovessels of bovine retina
    • Roberts JM, Forrester JV: Factors affecting the migration and growth of endothelial cells from icrovessels of bovine retina. Exp Eye Res, 1990; 50: 165-72
    • (1990) Exp Eye Res , vol.50 , pp. 165-172
    • Roberts, J.M.1    Forrester, J.V.2
  • 87
    • 11144230943 scopus 로고    scopus 로고
    • Decreased Thickness and Integrity of the Macular Elastic Layer of Bruch's Membrane Correspond to the Distribution of Lesions Associated with Age-Related Macular Degeneration
    • Chong NHV, Keonin J, Luthert PJ et al: Decreased Thickness and Integrity of the Macular Elastic Layer of Bruch's Membrane Correspond to the Distribution of Lesions Associated with Age-Related Macular Degeneration. Am J Pathol, 2005; 166(1): 240-51
    • (2005) Am J Pathol , vol.166 , Issue.1 , pp. 240-251
    • Chong, N.H.V.1    Keonin, J.2    Luthert, P.J.3
  • 88
    • 41949102294 scopus 로고    scopus 로고
    • Elastin gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
    • Kondo N, Honda S, Ishibashi K et al: Elastin gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci, 2008; 49: 1101-5
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1101-1105
    • Kondo, N.1    Honda, S.2    Ishibashi, K.3
  • 89
    • 0030788508 scopus 로고    scopus 로고
    • Elastin degradation products induce adventitial angiogenesis in the Anidjar/Dobrin rat aneurysm model
    • Nackman G, Karkowski F, Halpern V et al: Elastin degradation products induce adventitial angiogenesis in the Anidjar/Dobrin rat aneurysm model. Surgery, 1997; 122: 39-44
    • (1997) Surgery , vol.122 , pp. 39-44
    • Nackman, G.1    Karkowski, F.2    Halpern, V.3
  • 90
    • 34047195173 scopus 로고    scopus 로고
    • Case-control genetic association study of fibulin-6 (FBLN6 or HMCN1) variants in age-related macular degeneration (AMD)
    • Fisher SA, Rivera A, Fritsche LG et al: Case-control genetic association study of fibulin-6 (FBLN6 or HMCN1) variants in age-related macular degeneration (AMD). Hum Mutat, 2007; 28: 406-13
    • (2007) Hum Mutat , vol.28 , pp. 406-413
    • Fisher, S.A.1    Rivera, A.2    Fritsche, L.G.3
  • 91
    • 0348013124 scopus 로고    scopus 로고
    • Analysis of the ARMD1 locus: Evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family
    • Schultz DW, Klein ML, Humpert AJ et al: Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family. Hum Mol Genet, 2003; 12: 3315-23
    • (2003) Hum Mol Genet , vol.12 , pp. 3315-3323
    • Schultz, D.W.1    Klein, M.L.2    Humpert, A.J.3
  • 92
    • 77649187192 scopus 로고    scopus 로고
    • Focus on molecules: Fibulin-3 (EFEMP1)
    • Zhang Y, Marmorstein LY: Focus on molecules: Fibulin-3 (EFEMP1). Exp Eye Res, 2010; 90: 374-75
    • (2010) Exp Eye Res , vol.90 , pp. 374-375
    • Zhang, Y.1    Marmorstein, L.Y.2
  • 93
    • 34848894584 scopus 로고    scopus 로고
    • The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice
    • Fu L, Garland D, Yang Z et al: The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice. Hum Mol Genet, 2007; 16: 3411-22
    • (2007) Hum Mol Genet , vol.16 , pp. 3411-3422
    • Fu, L.1    Garland, D.2    Yang, Z.3
  • 94
    • 0036792087 scopus 로고    scopus 로고
    • Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration
    • Marmorstein LY, Munier FL, Arsenijevic Y et al: Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration. Proc Natl Acad Sci USA, 2002; 99: 13067-72
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13067-13072
    • Marmorstein, L.Y.1    Munier, F.L.2    Arsenijevic, Y.3
  • 95
    • 3242719404 scopus 로고    scopus 로고
    • Missense variations in the fibulin 5 gene and age-related macular degeneration
    • Stone EM, Braun TA, Russell SR et al: Missense variations in the fibulin 5 gene and age-related macular degeneration. N Engl J Med, 2004; 351: 346-53
    • (2004) N Engl J Med , vol.351 , pp. 346-353
    • Stone, E.M.1    Braun, T.A.2    Russell, S.R.3
  • 96
    • 0033027071 scopus 로고    scopus 로고
    • A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy
    • Stone EM, Lotery AJ, Munier FL et al: A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy. Nat Genet, 1999; 22: 199-202
    • (1999) Nat Genet , vol.22 , pp. 199-202
    • Stone, E.M.1    Lotery, A.J.2    Munier, F.L.3
  • 97
    • 0025044533 scopus 로고
    • Identification and localization of a beta1 receptor from the integrin family in mammalian retinal pigment epithelial cells
    • Anderson DH, Guerin CJ, Matsumoto B, Pfeffer BA: Identification and localization of a beta1 receptor from the integrin family in mammalian retinal pigment epithelial cells. Invest Ophthalmol Vis Sci, 1990; 31: 81-93
    • (1990) Invest Ophthalmol Vis Sci , vol.31 , pp. 81-93
    • Anderson, D.H.1    Guerin, C.J.2    Matsumoto, B.3    Pfeffer, B.A.4
  • 98
    • 0034604635 scopus 로고    scopus 로고
    • Urinary-type plasminogen activator (uPA) expression and uPA receptor localization are regulated by alpha 3 beta 1 integrin in oral keratinocytes
    • Ghosh S, Brown R, Jones JC et al: Urinary-type plasminogen activator (uPA) expression and uPA receptor localization are regulated by alpha 3 beta 1 integrin in oral keratinocytes. J Biol Chem, 2000; 275: 23869-76
    • (2000) J Biol Chem , vol.275 , pp. 23869-23876
    • Ghosh, S.1    Brown, R.2    Jones, J.C.3
  • 100
    • 0030087944 scopus 로고    scopus 로고
    • Aassembly of basement membranes
    • Timpl R, Brown JC: Aassembly of basement membranes. Bio Essays, 1996; 18: 123-32
    • (1996) Bio Essays , vol.18 , pp. 123-132
    • Timpl, R.1    Brown, J.C.2
  • 102
    • 0031038013 scopus 로고    scopus 로고
    • Roles of integrins in fibronectin matrix assembly
    • Wu C: Roles of integrins in fibronectin matrix assembly. Histol Histopathol, 1997; 12: 233-40
    • (1997) Histol Histopathol , vol.12 , pp. 233-240
    • Wu, C.1
  • 103
    • 0033535485 scopus 로고    scopus 로고
    • Basement membrane: Putting up the barriers
    • Schwarzbauer J: Basement membrane: Putting up the barriers. Current Biology, 1999; 9: R242-44
    • (1999) Current Biology , vol.9
    • Schwarzbauer, J.1
  • 104
    • 0033485457 scopus 로고    scopus 로고
    • Responses of vascular smooth muscle cell to extracellular matrix degradation
    • Tummalapalli C, Tyagi S: Responses of vascular smooth muscle cell to extracellular matrix degradation. J Cell Biochem, 1999; 75: 515-27
    • (1999) J Cell Biochem , vol.75 , pp. 515-527
    • Tummalapalli, C.1    Tyagi, S.2
  • 105
  • 106
    • 0035106148 scopus 로고    scopus 로고
    • Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium
    • Schwesinger C, Yee C, Rohan R: Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium. Am J Pathol, 2001; 158: 1161-72
    • (2001) Am J Pathol , vol.158 , pp. 1161-1172
    • Schwesinger, C.1    Yee, C.2    Rohan, R.3
  • 107
    • 0033882695 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization
    • Spilsbury K, Garrett K, Shen W et al: Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization. Am J Pathol, 2000; 157: 135-44
    • (2000) Am J Pathol , vol.157 , pp. 135-144
    • Spilsbury, K.1    Garrett, K.2    Shen, W.3
  • 108
    • 0020535731 scopus 로고
    • Selective proteolysis of immunoglobulins by mouse macrophage elastase
    • Banda MJ, Clark EJ, Werb Z: Selective proteolysis of immunoglobulins by mouse macrophage elastase. J Exp Med, 1983; 157: 1184-96
    • (1983) J Exp Med , vol.157 , pp. 1184-1196
    • Banda, M.J.1    Clark, E.J.2    Werb, Z.3
  • 109
    • 0019159424 scopus 로고
    • Limited proteolysis by macrophage elastase inactivates human a-1-proteinase inhibitor
    • Banda JJ, Clark EJ, Werb Z: Limited proteolysis by macrophage elastase inactivates human a-1-proteinase inhibitor. J Exp Med, 1980; 152: 1563-70
    • (1980) J Exp Med , vol.152 , pp. 1563-1570
    • Banda, J.J.1    Clark, E.J.2    Werb, Z.3
  • 110
    • 33644859329 scopus 로고    scopus 로고
    • Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD
    • Espinosa-Heidmann DG, Suner IJ, Catanuto P et al: Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD. Invest Ophthalmol Vis Sci, 2006; 47(2): 729-38
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.2 , pp. 729-738
    • Espinosa-Heidmann, D.G.1    Suner, I.J.2    Catanuto, P.3
  • 111
    • 34249652351 scopus 로고    scopus 로고
    • Antielastin autoimmunity in tobacco smoking-induced emphysema
    • Lee SH, Goswami, S Grudo A et al: Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med, 2007; 13: 567-69
    • (2007) Nat Med , vol.13 , pp. 567-569
    • Lee, S.H.1    Goswami, S.2    Grudo, A.3
  • 112
    • 37749042745 scopus 로고    scopus 로고
    • Plasma levels of matrix metalloproteinase-2 and-9 (MMP-2 and MMP-9) in age-related macular degeneration
    • Chau KY, Sivaprasad S, Patel N et al: Plasma levels of matrix metalloproteinase-2 and-9 (MMP-2 and MMP-9) in age-related macular degeneration. Eye, 2007; 21: 1511-15
    • (2007) Eye , vol.21 , pp. 1511-1515
    • Chau, K.Y.1    Sivaprasad, S.2    Patel, N.3
  • 113
    • 0035844299 scopus 로고    scopus 로고
    • Rac1 mediates type I collagen-dependent MMP-2 activation role in cell invasion across collagen barrier
    • Zhuge Y, Xu J: Rac1 mediates type I collagen-dependent MMP-2 activation role in cell invasion across collagen barrier. J Biol Chem, 2001; 276: 16248-56
    • (2001) J Biol Chem , vol.276 , pp. 16248-16256
    • Zhuge, Y.1    Xu, J.2
  • 114
    • 0036343595 scopus 로고    scopus 로고
    • Drusen are cold spots for proteolysis: Expression of matrix metalloproteinases and their tissue inhibitor proteins in age-related macular degeneration
    • Leu ST, Batni S, Radeke MJ et al: Drusen are cold spots for proteolysis: expression of matrix metalloproteinases and their tissue inhibitor proteins in age-related macular degeneration. Exp Eye Res, 2002; 74: 141-54
    • (2002) Exp Eye Res , vol.74 , pp. 141-154
    • Leu, S.T.1    Batni, S.2    Radeke, M.J.3
  • 115
    • 38549098235 scopus 로고    scopus 로고
    • MMP-14 and TIMP-2 overexpression protects against hydroquinone-induced oxidant injury in RPE: Implications for extracellular matrix turnover
    • Alcazar O: MMP-14 and TIMP-2 overexpression protects against hydroquinone-induced oxidant injury in RPE: implications for extracellular matrix turnover. Invest Ophthalmol Vis Sci, 2007; 48: 5662-70
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 5662-5670
    • Alcazar, O.1
  • 116
  • 117
    • 0032838202 scopus 로고    scopus 로고
    • Scavenger receptors and oxidized low density lipoproteins
    • Dhaliwal BS, Steinbrecher UP: Scavenger receptors and oxidized low density lipoproteins. Clin Chim Acta, 1999; 286: 191-205
    • (1999) Clin Chim Acta , vol.286 , pp. 191-205
    • Dhaliwal, B.S.1    Steinbrecher, U.P.2
  • 118
    • 0032521142 scopus 로고    scopus 로고
    • Divergent effects of tissue inhibitor of metalloproteinase-1,-2, or-3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro TIMP-3 promotes apoptosis
    • Baker AH, Zaltsman AB, George SJ, Newby AC: Divergent effects of tissue inhibitor of metalloproteinase-1,-2, or-3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro TIMP-3 promotes apoptosis. J Clin Invest, 1998; 101: 1478-87
    • (1998) J Clin Invest , vol.101 , pp. 1478-1487
    • Baker, A.H.1    Zaltsman, A.B.2    George, S.J.3    Newby, A.C.4
  • 119
    • 0029556810 scopus 로고
    • Genomic organization of the human Tissue Inhibitor of Metalloproteinases-3 (TIMP3)
    • Stohr H, Roomp K, Felbor U, Weber BHF: Genomic organization of the human Tissue Inhibitor of Metalloproteinases-3 (TIMP3). Genome Res, 1995; 5: 483-87
    • (1995) Genome Res , vol.5 , pp. 483-487
    • Stohr, H.1    Roomp, K.2    Felbor, U.3    Weber, B.H.F.4
  • 120
    • 0032820720 scopus 로고    scopus 로고
    • TIMP-3 in Bruch's membrane: Changes during aging and in age-related macular degeneration
    • Kamei M, Hollyfield JG: TIMP-3 in Bruch's membrane: changes during aging and in age-related macular degeneration. Invest Ophthalmol Vis Sci, 1999; 40: 2367-75
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2367-2375
    • Kamei, M.1    Hollyfield, J.G.2
  • 121
    • 0025935280 scopus 로고
    • A metalloproteinase inhibitor as an inhibitor of neovascularization
    • Moses MA, Langer R: A metalloproteinase inhibitor as an inhibitor of neovascularization. J Cell Biochem, 1991; 47; 230-35
    • (1991) J Cell Biochem , vol.47 , pp. 230-235
    • Moses, M.A.1    Langer, R.2
  • 122
    • 0023199438 scopus 로고
    • Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body
    • Newsome DA, Hewitt AT, Huh W et al: Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body. Am J Ophthalmol, 1987; 104: 373-81
    • (1987) Am J Ophthalmol , vol.104 , pp. 373-381
    • Newsome, D.A.1    Hewitt, A.T.2    Huh, W.3
  • 123
    • 0028820897 scopus 로고
    • Preparation of Bruch's membrane and analysis of the age-related changes in the structural collagens
    • Karwatowski WS, Jeffries TE, Duance VC et al: Preparation of Bruch's membrane and analysis of the age-related changes in the structural collagens. Br J Ophthalmol, 1995; 79: 944-52
    • (1995) Br J Ophthalmol , vol.79 , pp. 944-952
    • Karwatowski, W.S.1    Jeffries, T.E.2    Duance, V.C.3
  • 124
    • 0024535473 scopus 로고
    • Scanning electron microscopic observation of Bruch's membrane with the osmium tetroxide treatment
    • Yamamoto T, Yamashita H: Scanning electron microscopic observation of Bruch's membrane with the osmium tetroxide treatment. Br J Ophthalmol, 1989; 73: 162-67
    • (1989) Br J Ophthalmol , vol.73 , pp. 162-167
    • Yamamoto, T.1    Yamashita, H.2
  • 125
    • 0032786405 scopus 로고    scopus 로고
    • Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with agerelated macular degeneration and histologic examination of surgically excised choroidal neovascular membranes
    • Spraul CW, Lang GE, Grossniklaus HE, Lang GK: Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with agerelated macular degeneration and histologic examination of surgically excised choroidal neovascular membranes. Surv Ophthalmol, 1999; 44(Suppl.1): S10-32
    • (1999) Surv Ophthalmol , vol.44 , Issue.SUPPL. 1
    • Spraul, C.W.1    Lang, G.E.2    Grossniklaus, H.E.3    Lang, G.K.4
  • 126
    • 0033520641 scopus 로고    scopus 로고
    • Histopathology of age-related macular degeneration
    • Green WR: Histopathology of age-related macular degeneration. Mol Vis, 1999; 5: 27
    • (1999) Mol Vis , vol.5 , pp. 27
    • Green, W.R.1
  • 127
    • 0028057232 scopus 로고
    • Immunohistochemical light and electron microscopy of basal laminar deposit Graefes
    • van der Schaft TL, Mooy CM, de Bruijn WC et al: Immunohistochemical light and electron microscopy of basal laminar deposit Graefes Arch Clin Exp Ophthalmol, 1994; 232: 40-46
    • (1994) Arch Clin Exp Ophthalmol , vol.232 , pp. 40-46
    • van der Schaft, T.L.1    Mooy, C.M.2    de Bruijn, W.C.3
  • 128
    • 0026508815 scopus 로고
    • Histologic features of the early stages of age-related macular degeneration: A statistical analysis
    • van der Schaft TL, Mooy CM, de Bruijn WC et al: Histologic features of the early stages of age-related macular degeneration: A statistical analysis. Ophthalmology, 1992; 99: 278-86
    • (1992) Ophthalmology , vol.99 , pp. 278-286
    • van der Schaft, T.L.1    Mooy, C.M.2    de Bruijn, W.C.3
  • 129
    • 0025038027 scopus 로고
    • Aging changes in Bruch's membrane: A histochemical and morphologic study
    • Pauleikhoff D, Harper CA, Marshall J, Bird AC: Aging changes in Bruch's membrane: a histochemical and morphologic study. Ophthalmology, 1990b; 97: 171-78
    • (1990) Ophthalmology , vol.97 , pp. 171-178
    • Pauleikhoff, D.1    Harper, C.A.2    Marshall, J.3    Bird, A.C.4
  • 130
    • 0027473677 scopus 로고
    • Correlation between lipids extracted from Bruch's membrane and age
    • Sheraidah G, Steinmetz R, Maguire J et al: Correlation between lipids extracted from Bruch's membrane and age. Ophthalmology, 1993; 100: 47-51
    • (1993) Ophthalmology , vol.100 , pp. 47-51
    • Sheraidah, G.1    Steinmetz, R.2    Maguire, J.3
  • 131
    • 0033499606 scopus 로고    scopus 로고
    • Characterization of peroxidized lipids in Bruch's membrane
    • Spaide RF, Ho-Spaide WC, Browne RW, Armstrong D: Characterization of peroxidized lipids in Bruch's membrane. Retina, 1999; 19: 141-47
    • (1999) Retina , vol.19 , pp. 141-147
    • Spaide, R.F.1    Ho-Spaide, W.C.2    Browne, R.W.3    Armstrong, D.4
  • 133
    • 0035674910 scopus 로고    scopus 로고
    • Pulsatile ocular blood flow in asymmetric exudative age-related macular degeneration
    • Chen SJ, Cheng CY, Lee AF et al: Pulsatile ocular blood flow in asymmetric exudative age-related macular degeneration. Br J Ophthalmol, 2001; 85; 1411-15
    • (2001) Br J Ophthalmol , vol.85 , pp. 1411-1415
    • Chen, S.J.1    Cheng, C.Y.2    Lee, A.F.3
  • 134
    • 0036268571 scopus 로고    scopus 로고
    • Quantifying changes in RPE and choroidal vasculature in eyes with age-related macular degeneration
    • McLeod DS, Taomoto M, Otsuji T et al: Quantifying changes in RPE and choroidal vasculature in eyes with age-related macular degeneration Invest Ophthalmol Vis Sci, 2002; 43: 1986-93
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1986-1993
    • McLeod, D.S.1    Taomoto, M.2    Otsuji, T.3
  • 135
    • 0027985783 scopus 로고
    • High-resolution histologic analysis of the human choroidal vasculature
    • McLeod DS, Lutty GA: High-resolution histologic analysis of the human choroidal vasculature. Invest Ophthalmol Vis Sci, 1994; 35: 3799-811
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3799-3811
    • McLeod, D.S.1    Lutty, G.A.2
  • 136
    • 0030746588 scopus 로고    scopus 로고
    • Decreased choriocapillaris perfusion following surgical excision of choroidal neovascular membranes in age-related macular degeneration
    • Nasir M, Sugino I, Zarbin MA: Decreased choriocapillaris perfusion following surgical excision of choroidal neovascular membranes in age-related macular degeneration. Br J Ophthalmol, 1997; 81: 481-89
    • (1997) Br J Ophthalmol , vol.81 , pp. 481-489
    • Nasir, M.1    Sugino, I.2    Zarbin, M.A.3
  • 137
    • 20444430102 scopus 로고    scopus 로고
    • Basal deposits and drusen in eyes with age-related maculopathy: Evidence for solid lipid particles
    • Curcio CA, Presley JB, Millican CL, Medeiros NE: Basal deposits and drusen in eyes with age-related maculopathy: evidence for solid lipid particles. Exp Eye Res, 2005; 80: 761-75
    • (2005) Exp Eye Res , vol.80 , pp. 761-775
    • Curcio, C.A.1    Presley, J.B.2    Millican, C.L.3    Medeiros, N.E.4
  • 138
    • 0344791691 scopus 로고    scopus 로고
    • Basal linear deposit and large drusen are specific for early age-related maculopathy
    • Curcio CA, Millican CL: Basal linear deposit and large drusen are specific for early age-related maculopathy. Arch Ophthalmol, 1999; 117: 329-39
    • (1999) Arch Ophthalmol , vol.117 , pp. 329-339
    • Curcio, C.A.1    Millican, C.L.2
  • 139
    • 34047244381 scopus 로고    scopus 로고
    • Relationship of basal laminar deposit and membranous debris to the clinical presentation of early age-related macular degeneration
    • Sarks SH, Cherepanoff S, Killingsworth M, Sarks J: Relationship of basal laminar deposit and membranous debris to the clinical presentation of early age-related macular degeneration. Invest Ophthal Vis Sci, 2007; 48: 968-77
    • (2007) Invest Ophthal Vis Sci , vol.48 , pp. 968-977
    • Sarks, S.H.1    Cherepanoff, S.2    Killingsworth, M.3    Sarks, J.4
  • 140
    • 0027452475 scopus 로고
    • Age-related macular degeneration histopathologic studies
    • Green WR, Enger C: Age-related macular degeneration histopathologic studies. Ophthalmology, 1993; 100: 1519-35
    • (1993) Ophthalmology , vol.100 , pp. 1519-1535
    • Green, W.R.1    Enger, C.2
  • 141
    • 2442651836 scopus 로고    scopus 로고
    • The influence of path length and matrix components on ageing characteristics of transport between the choroid and the outer retina
    • Hillenkamp J, Hussain AA, Jackson TL et al: The influence of path length and matrix components on ageing characteristics of transport between the choroid and the outer retina. Invest Ophthalmol Vis Sci, 2004; 45: 1493-98
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1493-1498
    • Hillenkamp, J.1    Hussain, A.A.2    Jackson, T.L.3
  • 142
    • 0036364559 scopus 로고    scopus 로고
    • Age-related alterations in the diffusional transport of amino acids across the human Bruch's-choroid complex
    • Hussain AA, Rowe L, Marshall J: Age-related alterations in the diffusional transport of amino acids across the human Bruch's-choroid complex. J Opt Soc Am A Opt Image Sci Vis, 2002; 19(1): 166-72
    • (2002) J Opt Soc Am A Opt Image Sci Vis , vol.19 , Issue.1 , pp. 166-172
    • Hussain, A.A.1    Rowe, L.2    Marshall, J.3
  • 143
    • 0034755091 scopus 로고    scopus 로고
    • The effect of age on the macromolecular permeability of human Bruch's membrane
    • Moore DJ, Clover GM: The effect of age on the macromolecular permeability of human Bruch's membrane. Invest Ophthalmol Vis Sci, 2001; 42: 2970-75
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2970-2975
    • Moore, D.J.1    Clover, G.M.2
  • 144
    • 0029950660 scopus 로고    scopus 로고
    • Hydrodynamics of ageing Bruch's membrane: Implications for macular disease
    • Starita C, Hussain AA, Pagliarini S, Marshall J: Hydrodynamics of ageing Bruch's membrane: implications for macular disease. Exp Eye Res, 1996; 62: 565-72
    • (1996) Exp Eye Res , vol.62 , pp. 565-572
    • Starita, C.1    Hussain, A.A.2    Pagliarini, S.3    Marshall, J.4
  • 145
    • 18044366931 scopus 로고    scopus 로고
    • RPE lipofuscin and its role in retinal pathobiology
    • Sparrow JR, Boulton M: RPE lipofuscin and its role in retinal pathobiology Exp Eye Res, 2005; 80(5): 595-606
    • (2005) Exp Eye Res , vol.80 , Issue.5 , pp. 595-606
    • Sparrow, J.R.1    Boulton, M.2
  • 146
    • 47849092882 scopus 로고    scopus 로고
    • Retinal pigment epithelium lipofuscin proteomics
    • Ng KP, Gugiu B, Renganathan K et al: Retinal pigment epithelium lipofuscin proteomics. Mol Cell Proteomics, 2008; 7(7): 1397-405
    • (2008) Mol Cell Proteomics , vol.7 , Issue.7 , pp. 1397-1405
    • Ng, K.P.1    Gugiu, B.2    Renganathan, K.3
  • 147
    • 29244435041 scopus 로고    scopus 로고
    • Examining the proteins of functional retinal lipofuscin using proteomic analysis as a guide for understanding its origin
    • Warburton S, Southwick K, Hardman RM et al: Examining the proteins of functional retinal lipofuscin using proteomic analysis as a guide for understanding its origin. Mol Vis, 2005; 15(11): 1122-34
    • (2005) Mol Vis , vol.15 , Issue.11 , pp. 1122-1134
    • Warburton, S.1    Southwick, K.2    Hardman, R.M.3
  • 148
    • 68649113530 scopus 로고    scopus 로고
    • New components of 'basal laminar deposits' in age-related macular degeneration
    • Reale E, Groos S, Eckardt U et al: New components of 'basal laminar deposits' in age-related macular degeneration. Cells Tissues Organs, 2009; 190: 170-81
    • (2009) Cells Tissues Organs , vol.190 , pp. 170-181
    • Reale, E.1    Groos, S.2    Eckardt, U.3
  • 149
    • 11144258543 scopus 로고    scopus 로고
    • Drusen proteome anlysis: An approach to the etiology of age-related macular degeneration
    • Crabb JW, Miyagi M, Gu X et al: Drusen proteome anlysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci USA, 2002; 99(23): 14682-87
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.23 , pp. 14682-14687
    • Crabb, J.W.1    Miyagi, M.2    Gu, X.3
  • 150
    • 0033040280 scopus 로고    scopus 로고
    • Early drusen formation in the normal and aging eye and their relation to age related maculopathy: A clinicopathological study
    • Sarks SH, Arnold JJ, Killingsworth MC, Sarks JP: Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study. Br J Ophthalmol, 1999; 83(3): 358-68
    • (1999) Br J Ophthalmol , vol.83 , Issue.3 , pp. 358-368
    • Sarks, S.H.1    Arnold, J.J.2    Killingsworth, M.C.3    Sarks, J.P.4
  • 151
    • 26444583909 scopus 로고    scopus 로고
    • Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different of macular degeneration in cynomolgus monkey (Macaca fascicularis)
    • Umeda S, Suzuki MT, Okamoto H et al: Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different of macular degeneration in cynomolgus monkey (Macaca fascicularis). FASEB J, 2005; 19(12): 1683-85
    • (2005) FASEB J , vol.19 , Issue.12 , pp. 1683-1685
    • Umeda, S.1    Suzuki, M.T.2    Okamoto, H.3
  • 152
    • 27744516278 scopus 로고    scopus 로고
    • A simplified severity scale for age-related macular degeneration: AREDS Report No 18
    • Ferris FL, Davis MD, Clemons TE et al: A simplified severity scale for age-related macular degeneration: AREDS Report No 18. Arch Ophthalmol, 2005; 123: 1570-74
    • (2005) Arch Ophthalmol , vol.123 , pp. 1570-1574
    • Ferris, F.L.1    Davis, M.D.2    Clemons, T.E.3
  • 153
    • 0038667890 scopus 로고    scopus 로고
    • Risk of age-related macular degeneration in eyes with macular drusen or hyperpigmentation: The Blue Mountains Eye Study Cohort
    • Wang JJ, Foran S, Smith W, Mitchell P: Risk of age-related macular degeneration in eyes with macular drusen or hyperpigmentation: The Blue Mountains Eye Study Cohort. Arch Ophthalmol, 2003; 121: 658-63
    • (2003) Arch Ophthalmol , vol.121 , pp. 658-663
    • Wang, J.J.1    Foran, S.2    Smith, W.3    Mitchell, P.4
  • 154
    • 0028921773 scopus 로고
    • Five-year incidence and disappearance of drusen and retinal pigment epithelial abnormalities Waterman study
    • Bressler NM, Munoz B, Maguire MG et al: Five-year incidence and disappearance of drusen and retinal pigment epithelial abnormalities Waterman study. Arch Ophthalmol, 1995; 113: 301-8
    • (1995) Arch Ophthalmol , vol.113 , pp. 301-308
    • Bressler, N.M.1    Munoz, B.2    Maguire, M.G.3
  • 155
    • 0025153129 scopus 로고
    • Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. The Macular Photocoagulation Study Group
    • Bressler SB, Maguire MG, Bressler NM, Fine SL: Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. The Macular Photocoagulation Study Group. Arch Ophthalmol, 1990; 108: 1442-47
    • (1990) Arch Ophthalmol , vol.108 , pp. 1442-1447
    • Bressler, S.B.1    Maguire, M.G.2    Bressler, N.M.3    Fine, S.L.4
  • 156
    • 0031056911 scopus 로고    scopus 로고
    • The five-year incidence and progression of age-related maculopathy: The Beaver Dam Eye Study
    • Klein R, Klein BE, Jensen SC, Meuer SM: The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study. Ophthalmology, 1997; 104: 7-21
    • (1997) Ophthalmology , vol.104 , pp. 7-21
    • Klein, R.1    Klein, B.E.2    Jensen, S.C.3    Meuer, S.M.4
  • 157
    • 0033499808 scopus 로고    scopus 로고
    • Long-term drusen study
    • Sarraf D, Gin T, Yu F et al: Long-term drusen study. Retina, 1999; 19: 513-19
    • (1999) Retina , vol.19 , pp. 513-519
    • Sarraf, D.1    Gin, T.2    Yu, F.3
  • 158
    • 0002298051 scopus 로고    scopus 로고
    • Age-related maculopathy: Nonneovascular age-related macular degeneration and the evolution of geographic atrophy
    • rd ed. St Louis, Mosby
    • rd ed. St Louis, Mosby, 2001: 1064-99
    • (2001) Medical Retina , pp. 1064-1099
    • Sarks, S.H.1    Sarks, J.P.2
  • 159
    • 0003304067 scopus 로고
    • Drusen share molecular constituents common to atherosclerotic, elastotic and amyloid deposits
    • Hageman GS, Mullins RF, Clark WG et al: Drusen share molecular constituents common to atherosclerotic, elastotic and amyloid deposits. Invest Ophthalmol Vis Sci, 1995; 36: 432
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 432
    • Hageman, G.S.1    Mullins, R.F.2    Clark, W.G.3
  • 160
    • 0034012166 scopus 로고    scopus 로고
    • Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis and dense deposit disease
    • Mullins RF, Russel SR, Anderson DH, Hageman GS: Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis and dense deposit disease. FASEB J, 2000; 14(7): 835-46
    • (2000) FASEB J , vol.14 , Issue.7 , pp. 835-846
    • Mullins, R.F.1    Russel, S.R.2    Anderson, D.H.3    Hageman, G.S.4
  • 162
    • 0028692220 scopus 로고
    • Biochemical and histochemical analysis of age related lipid deposits in Bruch's membrane
    • Pauleikhoff D, Sheraidah G, Marshall J et al: Biochemical and histochemical analysis of age related lipid deposits in Bruch's membrane. Ophthalmology, 1994; 91: 730-34
    • (1994) Ophthalmology , vol.91 , pp. 730-734
    • Pauleikhoff, D.1    Sheraidah, G.2    Marshall, J.3
  • 163
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV: A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol, 2002; 134: 411-31
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 164
    • 67649583541 scopus 로고    scopus 로고
    • Inflammation and pathogenesis of age-related macular degeneration
    • Augustin AJ, Kirchhof J: Inflammation and pathogenesis of age-related macular degeneration. Expert Opin Ther Targets, 2009; 13(6): 641-51
    • (2009) Expert Opin Ther Targets , vol.13 , Issue.6 , pp. 641-651
    • Augustin, A.J.1    Kirchhof, J.2
  • 165
    • 33144459399 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis age-related macular degeneration
    • Donoso LA, Kim D, Frost A et al: The role of inflammation in the pathogenesis age-related macular degeneration. Surv Ophthalmol, 2006; 51(2): 137-52
    • (2006) Surv Ophthalmol , vol.51 , Issue.2 , pp. 137-152
    • Donoso, L.A.1    Kim, D.2    Frost, A.3
  • 166
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPEBruch's membrane interface in aging and age-related macular degeneration
    • Hageman GS, Luther PJ, Chong VNH et al: An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPEBruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res, 2001; 20(6): 705-32
    • (2001) Prog Retin Eye Res , vol.20 , Issue.6 , pp. 705-732
    • Hageman, G.S.1    Luther, P.J.2    Chong, V.N.H.3
  • 167
    • 0033842370 scopus 로고    scopus 로고
    • A potential role for immune complex pathogenesis in drusen formation
    • Johnson LV, Ozaki S, Staples MK et al: A potential role for immune complex pathogenesis in drusen formation. Exp Eye Res, 2000; 70: 441-49
    • (2000) Exp Eye Res , vol.70 , pp. 441-449
    • Johnson, L.V.1    Ozaki, S.2    Staples, M.K.3
  • 168
    • 17844409078 scopus 로고    scopus 로고
    • Immunological factors in the pathogenesis and treatment of age-related macular degeneration
    • Kijlstra A, La Heij E, Hendrikse F: Immunological factors in the pathogenesis and treatment of age-related macular degeneration. Ocul Immunol Inflamm, 2005; 13(1): 3-11
    • (2005) Ocul Immunol Inflamm , vol.13 , Issue.1 , pp. 3-11
    • Kijlstra, A.1    La Heij, E.2    Hendrikse, F.3
  • 169
    • 67651155742 scopus 로고    scopus 로고
    • Para-inflammation in aging retina
    • Xu H, Chen M, Forrester JV: Para-inflammation in aging retina. Prog Retin Eye Res, 2009; 28(5): 348-68
    • (2009) Prog Retin Eye Res , vol.28 , Issue.5 , pp. 348-368
    • Xu, H.1    Chen, M.2    Forrester, J.V.3
  • 170
    • 61349122008 scopus 로고    scopus 로고
    • Complement component C3 and risk of age-related macular degeneration
    • Despriet DD, van Duijn CM, Oostra BA et al: Complement component C3 and risk of age-related macular degeneration. Ophthalmology, 2009; 116(3): 474-80
    • (2009) Ophthalmology , vol.116 , Issue.3 , pp. 474-480
    • Despriet, D.D.1    van Duijn, C.M.2    Oostra, B.A.3
  • 171
    • 0036978519 scopus 로고    scopus 로고
    • Macrophages and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization
    • Grossniklaus HE, Jing JX, Wallace TM et al: Macrophages and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization. Mol Vis, 2002; 21(8): 119-26
    • (2002) Mol Vis , vol.21 , Issue.8 , pp. 119-126
    • Grossniklaus, H.E.1    Jing, J.X.2    Wallace, T.M.3
  • 172
    • 22544431912 scopus 로고    scopus 로고
    • Complement and diseases: Defective alternative pathway control results in kidney and eye diseases
    • Zipfel PF, Heinen S, Józsi M, Skerka C: Complement and diseases: defective alternative pathway control results in kidney and eye diseases. Mol Immunol, 2006; 43: 97-106
    • (2006) Mol Immunol , vol.43 , pp. 97-106
    • Zipfel, P.F.1    Heinen, S.2    Józsi, M.3    Skerka, C.4
  • 173
    • 0033921540 scopus 로고    scopus 로고
    • Complement components of innate immune system in health and disease in the CNS
    • Gasgue P, Dean YD, McGreal EP et al: Complement components of innate immune system in health and disease in the CNS. Immunopharmacology, 2000; 49: 171-86
    • (2000) Immunopharmacology , vol.49 , pp. 171-186
    • Gasgue, P.1    Dean, Y.D.2    McGreal, E.P.3
  • 174
    • 2442433542 scopus 로고    scopus 로고
    • The human complement factor H: Functional roles, genetic variations and disease associations
    • Rodriguez de Cordoba SR, Esparza-Gordillo J, Goicoechea de Jorge E et al: The human complement factor H: functional roles, genetic variations and disease associations. Mol Immunol, 2004; 41: 355-67
    • (2004) Mol Immunol , vol.41 , pp. 355-367
    • Rodriguez de Cordoba, S.R.1    Esparza-Gordillo, J.2    Goicoechea de Jorge, E.3
  • 175
    • 62649135260 scopus 로고    scopus 로고
    • Complement activation by bisretinoid constituents of RPE lipofuscin
    • Zhou J, Kim SR, Westlund BS, Sparrow JR: Complement activation by bisretinoid constituents of RPE lipofuscin. Invest Ophthalmol Vis Sci, 2009;50(3): 1392-99
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.3 , pp. 1392-1399
    • Zhou, J.1    Kim, S.R.2    Westlund, B.S.3    Sparrow, J.R.4
  • 176
    • 33750814597 scopus 로고    scopus 로고
    • Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
    • Zhou J, Jang YP, Kim SR, Sparrow JR: Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium. Proc Natl Acad Sci USA, 2006; 103(44): 16182-87
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.44 , pp. 16182-16187
    • Zhou, J.1    Jang, Y.P.2    Kim, S.R.3    Sparrow, J.R.4
  • 177
    • 70249115440 scopus 로고    scopus 로고
    • Complement and immune defense: From innate immunity to human diseases
    • Zipfel PF: Complement and immune defense: from innate immunity to human diseases. Immunol Lett, 2009; 22(126): 1-7
    • (2009) Immunol Lett , vol.22 , Issue.126 , pp. 1-7
    • Zipfel, P.F.1
  • 178
    • 17244379811 scopus 로고    scopus 로고
    • Complement factor H polymorphism and age-related macular degeneration
    • Edwards A, Ritter R, Abel K et al: Complement factor H polymorphism and age-related macular degeneration. Science, 2005; 308: 421-24
    • (2005) Science , vol.308 , pp. 421-424
    • Edwards, A.1    Ritter, R.2    Abel, K.3
  • 179
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposesindividuals to agerelated macular degeneration
    • Hageman GS, Anderson D, Johnson L et al: A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposesindividuals to agerelated macular degeneration. Proc Natl Acad Sci USA, 2005; 102: 7227-32
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.2    Johnson, L.3
  • 180
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • Haines J, Hauser, M Schmidt S et al: Complement factor H variant increases the risk of age-related macular degeneration. Science, 2005; 308: 419-21
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.1    Hauser, M.2    Schmidt, S.3
  • 181
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in agerelated macular degeneration
    • Klein R, Zeiss C, Chew E et al: Complement factor H polymorphism in agerelated macular degeneration. Science, 2005; 308: 385-89
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.1    Zeiss, C.2    Chew, E.3
  • 182
    • 47749126514 scopus 로고    scopus 로고
    • Factor H family proteins and human diseases
    • Józsi M, Zipfel PF: Factor H family proteins and human diseases. Trends Immunol, 2008; 29(8): 380-87
    • (2008) Trends Immunol , vol.29 , Issue.8 , pp. 380-387
    • Józsi, M.1    Zipfel, P.F.2
  • 183
    • 0142242222 scopus 로고    scopus 로고
    • Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration
    • Gu X, Meer SG, Miyagi M et al: Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration. J Biol Chem, 2003; 278(43): 42027-35
    • (2003) J Biol Chem , vol.278 , Issue.43 , pp. 42027-42035
    • Gu, X.1    Meer, S.G.2    Miyagi, M.3
  • 184
    • 33646128251 scopus 로고    scopus 로고
    • Cell survival matters: Docosahexaenoic acid signaling, neuroprotection and photoreceptors
    • Bazan NG: Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors. Trends Neurosci, 2006; 29(5): 263-71
    • (2006) Trends Neurosci , vol.29 , Issue.5 , pp. 263-271
    • Bazan, N.G.1
  • 185
    • 8844256502 scopus 로고    scopus 로고
    • The role of omega-3 long-chain polyunsaturated fatty acid in health and disease of the retina
    • San Giovanni JP, Chew EY: The role of omega-3 long-chain polyunsaturated fatty acid in health and disease of the retina. Prog Retin Eye Res, 2005;24(1): 87-138
    • (2005) Prog Retin Eye Res , vol.24 , Issue.1 , pp. 87-138
    • San Giovanni, J.P.1    Chew, E.Y.2
  • 186
    • 0142059080 scopus 로고    scopus 로고
    • Docosahexaenoic acid: Membrane properties of a unique fatty acid
    • Stilwell W, Wassal SR: Docosahexaenoic acid: membrane properties of a unique fatty acid Chem Phys Lipids, 2003; 126(1): 1-27
    • (2003) Chem Phys Lipids , vol.126 , Issue.1 , pp. 1-27
    • Stilwell, W.1    Wassal, S.R.2
  • 187
    • 38949185692 scopus 로고    scopus 로고
    • Oxydative damage-induced inflammation initiates age-related macular degeneration
    • Hollyfield JG, Bonilha VL, Rayborn ME et al: Oxydative damage-induced inflammation initiates age-related macular degeneration. Nat Med, 2008;14(2): 194-98
    • (2008) Nat Med , vol.14 , Issue.2 , pp. 194-198
    • Hollyfield, J.G.1    Bonilha, V.L.2    Rayborn, M.E.3
  • 188
    • 38949196468 scopus 로고    scopus 로고
    • Carboxyethylpropyrrole adducts, age-related macular degeneration and neovascularization
    • Renganathan K, Ebrahem Q, Vasanji A et al: Carboxyethylpropyrrole adducts, age-related macular degeneration and neovascularization. Adv Exp Med Biol, 2008; 613: 261-67
    • (2008) Adv Exp Med Biol , vol.613 , pp. 261-267
    • Renganathan, K.1    Ebrahem, Q.2    Vasanji, A.3
  • 189
    • 33748605874 scopus 로고    scopus 로고
    • Carboxyethylpropyrrole oxidative protein modifications stimulate neovascularization: Implifications for age-related macular degeneration
    • Ebrachem Q, Renganathan K, Sears J et al: Carboxyethylpropyrrole oxidative protein modifications stimulate neovascularization: Implifications for age-related macular degeneration. Proc Natl Acad Sci USA, 2006; 103(36): 13480-84
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.36 , pp. 13480-13484
    • Ebrachem, Q.1    Renganathan, K.2    Sears, J.3
  • 190
    • 30344447284 scopus 로고    scopus 로고
    • Pigment epithelium derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroids and eyes with age-related macular degeneration
    • Bhutto IA, McLeod DS, Hasegawa T et al: Pigment epithelium derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroids and eyes with age-related macular degeneration. Exp Eye Res, 2006; 82: 99-110
    • (2006) Exp Eye Res , vol.82 , pp. 99-110
    • Bhutto, I.A.1    McLeod, D.S.2    Hasegawa, T.3
  • 191
    • 0141842524 scopus 로고    scopus 로고
    • Distribution of the serine protease HtrA1 in normal human tissues
    • De Luca A, De Falco M, Severino A et al: Distribution of the serine protease HtrA1 in normal human tissues. J Histochem Cytochem, 2003; 51: 1279-84
    • (2003) J Histochem Cytochem , vol.51 , pp. 1279-1284
    • De Luca, A.1    De Falco, M.2    Severino, A.3
  • 192
    • 33751011889 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism in wet age-related macular degeneration
    • De Wan A, Liu M, Harman S et al: HTRA1 promoter polymorphism in wet age-related macular degeneration. Science, 2006; 314: 989-92
    • (2006) Science , vol.314 , pp. 989-992
    • De Wan, A.1    Liu, M.2    Harman, S.3
  • 193
    • 33751004690 scopus 로고    scopus 로고
    • A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
    • Yang Z, Camp NC, Sun H et al: A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science, 2006; 314: 992-93
    • (2006) Science , vol.314 , pp. 992-993
    • Yang, Z.1    Camp, N.C.2    Sun, H.3
  • 194
    • 3142714511 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1): Implications for macular degenerations
    • Klenotic PA, Munier FL, Marmorstein LY, Anand-Apte B: Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1): implications for macular degenerations. J Biol Chem, 2004; 279; 30469-73
    • (2004) J Biol Chem , vol.279 , pp. 30469-30473
    • Klenotic, P.A.1    Munier, F.L.2    Marmorstein, L.Y.3    Anand-Apte, B.4
  • 195
    • 0032468842 scopus 로고    scopus 로고
    • Age-related macular degeneration: Clinical features in a large family and linkage to chromosome 1q
    • Klein ML, Schultz DW, Edwards A et al: Age-related macular degeneration: clinical features in a large family and linkage to chromosome 1q. Arch Ophthalmol, 1998; 116: 1082-88
    • (1998) Arch Ophthalmol , vol.116 , pp. 1082-1088
    • Klein, M.L.1    Schultz, D.W.2    Edwards, A.3
  • 196
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • Rivera A, Fisher SA, Fritsche LG et al: Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet, 2005; 14: 3227-36
    • (2005) Hum Mol Genet , vol.14 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3
  • 197
    • 67649998898 scopus 로고    scopus 로고
    • Age-related macular degeneration associated ARMS2 is not a mitochondrial but cytosolic protein
    • Wang G, Spencer KM, Court BL et al: Age-related macular degeneration associated ARMS2 is not a mitochondrial but cytosolic protein. Invest Ophthalmol Vis Sci, 2009; 50(7): 3084-90
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.7 , pp. 3084-3090
    • Wang, G.1    Spencer, K.M.2    Court, B.L.3
  • 198
    • 46249098503 scopus 로고    scopus 로고
    • Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
    • Fritsche LG, Loenhardt T, Janssen A et al: Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet, 2008; 40(7): 892-96
    • (2008) Nat Genet , vol.40 , Issue.7 , pp. 892-896
    • Fritsche, L.G.1    Loenhardt, T.2    Janssen, A.3
  • 199
    • 9144228044 scopus 로고    scopus 로고
    • Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration
    • Iyengar SK, Song D, Klein BE et al: Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet, 2004; 74: 20-39
    • (2004) Am J Hum Genet , vol.74 , pp. 20-39
    • Iyengar, S.K.1    Song, D.2    Klein, B.E.3
  • 200
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • Andreasen PA, Kjoller L, Christensen L, Duffy MF: The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer, 1997; 72: 1-22
    • (1997) Int J Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjoller, L.2    Christensen, L.3    Duffy, M.F.4
  • 201
    • 70349469696 scopus 로고    scopus 로고
    • Antiangiogenic approaches to age-related macular degeneration today
    • Bressler NM: Antiangiogenic approaches to age-related macular degeneration today. Ophthalmology, 2009; 116(10 Suppl.): 15-23
    • (2009) Ophthalmology , vol.116 , Issue.10 SUPPL. , pp. 15-23
    • Bressler, N.M.1
  • 202
    • 61449118750 scopus 로고    scopus 로고
    • Photodynamic therapy with verteporfin in age-related macular degeneration: Asystematic review of efficacy, safety, treatment modifications and pharmacoeconomic properties
    • Cruess AF, Zlateva G, Pleil AM, Wirostko B: Photodynamic therapy with verteporfin in age-related macular degeneration: asystematic review of efficacy, safety, treatment modifications and pharmacoeconomic properties. Acta Ophthalmol, 2009; 87(2): 118-32
    • (2009) Acta Ophthalmol , vol.87 , Issue.2 , pp. 118-132
    • Cruess, A.F.1    Zlateva, G.2    Pleil, A.M.3    Wirostko, B.4
  • 203
    • 84863554646 scopus 로고    scopus 로고
    • Combined treatment of exudative age-related macular degeneration with photodynamic therapy and intravitreal triamcinolone
    • Ruiz-Moreno JM, Montero JA: Combined treatment of exudative age-related macular degeneration with photodynamic therapy and intravitreal triamcinolone. Clin Ophthalmol, 2008; 2(1): 71-75
    • (2008) Clin Ophthalmol , vol.2 , Issue.1 , pp. 71-75
    • Ruiz-Moreno, J.M.1    Montero, J.A.2
  • 204
    • 63249121270 scopus 로고    scopus 로고
    • Verteporfin combination regimens in the treatment of neovascular age-related macular degeneration
    • Shah GK, Sang DN, Hughes MS: Verteporfin combination regimens in the treatment of neovascular age-related macular degeneration. Retina, 2009;29(2): 133-48
    • (2009) Retina , vol.29 , Issue.2 , pp. 133-148
    • Shah, G.K.1    Sang, D.N.2    Hughes, M.S.3


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