Drusen are cold spots for proteolysis: Expression of matrix metalloproteinases and their tissue inhibitor proteins in age-related macular degeneration

Experimental Eye Research

Volumn 74, Issue 1, 2002, Pages 141-154

  Leu, Sergiu T ^a   Batni, Suchitra ^a   Radeke, Monte J ^a   Johnson, Lincoln V ^a   Anderson, Don H ^a   Clegg, Dennis O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Age related macular degeneration; Bruch's membrane; Choroids; Collagenase; Drusen; Gelatinase; In situ zymography; Matrix metalloproteinase; Neurodegeneration; Retina; Retinal pigment epithelium; Tissue inhibitor of metalloproteinase

Indexed keywords

GELATINASE; GELATINASE A; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4;

ARTICLE; CELL CULTURE; CHOROID; CONTROLLED STUDY; DNA MICROARRAY; DRUSEN; ENZYME ACTIVITY; ENZYME INHIBITION; FETUS; FROZEN SECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETINA MACULA AGE RELATED DEGENERATION; RNA ANALYSIS;

EID: 0036343595     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.2001.1112     Document Type: Article

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