Increased extracellular deposition of fibrillin-containing fibrils in pseudoexfoliation syndrome

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 5, 1997, Pages 970-984

  Schlötzer Schrehardt, Ursula ^a   Von der Mark, Klaus ^a   Sakai, Lynn Y ^b   Naumann, Gottfried O H ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b SHRINERS HOSPITAL FOR CHILDREN   (United States)

Author keywords

electron microscopy; fibrillin; immunocytochemistry; microfibrils; pseudoexfoliation syndrome

Indexed keywords

FIBRILLIN;

AGED; ANIMAL TISSUE; ANTERIOR EYE SEGMENT; ARTICLE; CONTROLLED STUDY; HUMAN; IMMUNOFLUORESCENCE; IMMUNOGOLD STAINING; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PSEUDOEXFOLIATION; TISSUE DISTRIBUTION;

AGED; ANTERIOR EYE SEGMENT; ANTIBODIES, MONOCLONAL; CILIARY BODY; CONJUNCTIVA; CORNEA; EXFOLIATION SYNDROME; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; EYELIDS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IRIS; MICROFILAMENT PROTEINS; MICROSCOPY, IMMUNOELECTRON; MUSCLE, SMOOTH; TRABECULAR MESHWORK;

EID: 1842336913     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Schlötzer-Schrehardt U, Koca MR, Naumann GOH, Volkholz H. Pseucloexfoliation syndrome: Ocular manifestation of a systemic disorder? Arch Ophthalmol. 1992;110:1752-1756.
2. Streeten BW, Li Z-Y, Wallace RN, Eagle RC, Keshgegian AA. Pseudoexfoliative fihrillopathy in visceral organs of a patient with pseudoexfoliation syndrome. Arch Ophthalmol. 1992;110:1757-1762.
3. Forsius H. Exfoliation syndrome in various ethnic populations. Acta Ophthalmol Scand. 1988;66(Suppl) 184:71-85.
4. Schlötzer-Schrehardt U, Dörfler S, Naumann GOH. Immunohistochemical localization of basement membrane components in pseudoexfoliation material of the lens capsule. Curr Eye Res. 1992;11:343-355.
5. Streeten BW, Gibson SA, Dark AJ. Pseudoexfoliative material contains an elastic microfibrillar-associated glycoprotein. Trans Am Ophthalmol Soc. 1986;84:304-320.
6. Li Z-Y, Streeten BW, Wallace RN. Association of elastin with pseudoexfoliative material: An immunoelectron microscopic study. Curr Eye Res. 1988;7:1163-1172.
7. Li Z-Y, Streeten BW, Yohai N. Amyloid P protein in pseudoexfoliative fibrillopathy. Curr Eye Res. 1989; 8:217-227.
8. Eagle RC, Font RL, Fine BS. The basement membrane exfoliation syndrome. Arch Ophthalmol. 1979;97:510-515.
9. Streeten BW, Bookman L, Ritch R, Prince AM, Dark AJ. Pseudoexfoliative fibrillopathy in the conjunctiva: A relation to elastic fibers and elastosis. Ophthalmology. 1987;94:1439-1449.
10. Streeten BW, Dark AJ, Wallace RN, Li Z-Y, Hoepner JA. Pseudoexfoliative fibrillopathy in the skin of patients with ocular pseudoexfoliation. Am J Ophthalmol. 1990;110:490-499.
11. Cleary EG. The microfibrillar component of the elastic fibers: Morphology and biochemistry. In: Uitto J, Perejda AJ, eds. Connective Tissue Disease: The Molecular Pathology of the Extracellular Matrix. New York: Marcel Dekker; 1987:55-81.
12. Mecham RP, Heuser JE. The elastic fiber. In: Hay ED, ed. Cell Biology of the Extracellular Matrix. New York: Plenum Publishing Co; 1991:79-109.
13. Kielty CM, Shuttleworth CA, Fibrillin-containing microfibrils: Structure and function in health and disease. Int J Biochem Cell Biol. 1995;27:747-760.
14. Sakai LY, Keene DR, Engvall E. Fibrillin, a new 350- kD glycoprotein, is a component of extracellular microfibrils. J Cell Biol. 1986;103:2499-2509.
15. Sakai LY, Keene DR, Glanville RW, Bächinger HP. Purification and partial characterization of fibrillin, a cysteine-rich structural component of connective tissue microfibrils. J Biol Chem. 1991;266:14763-14770.
16. Morrison JC, Jerdan JA, Dorman ME, Quigley HA. Structural proteins of the neonatal and adult lamina cribrosa. Arch Ophthalmol. 1989;107:1220-1224.
17. Wallace RN, Streeten BW, Hanna RB. Rotary shadowing of elastic system microfibrils in the ocular zonule, vitreous, and ligamentum nuchae. Curr Eye Res. 1991;10:99-109.
18. Wheatley HM, Traboulsi EI, Flowers BE, et al. Immunohistochemical localization of fibrillin in human ocular tissues. Arch Ophthalmol 1995;113:103-109.
19. Ramirez F, Pereira L, Zhang H, Lee B. The fibrillin-Marfan syndrome connection. Bioessays. 1993;15:589-594.
20. Dietz HC, Ramirez F, Sakai LY. Marian's syndrome and other microfibrillar diseases. In: Harris H, Hirschhorn K, eds. Advances in Human Genetics 22. New York: Plenum Press; 1994:153-185.
21. Maumenee IH. The eye in the Marfan syndrome. Trans Am Ophthalmol Soc. 1981;79:684-733.
22. Schlötzer-Schrehardt U, Naumann GOH. A histopathologic study of zonular instability in pseudoexfoliation syndrome. Am J Ophthalmol. 1994;118:730-743.
23. Dark AJ, Streeten BW. Precapsular film on the aging human lens: Precursor of pseudoexfoliation? Br J Ophthalmol. 1990;74:717-722.
24. Lütjen-Drecoll E, Rohen JW. Morphology of aqueous outflow pathways in normal and glaucomatous eyes. In: Ritch R, Shields MB, Krupin T, eds. The Glaucomas. St Louis: Mosby; 1996:89-123.
25. Dahlbäck K, Ljungquist A, Löfberg H, Dahlbäck B, Engvall E, Sakai LY. Fibrillin immunoreactive fibers constitute a unique network in the human dermis: Immunohistochemical comparison of the distributions of fibrillin, vitronectin, amyloid P component, and orcein stainable structures in normal skin and elastosis. J Invest Dermatol 1990;94:284-291.
26. Fleischmajer R, Jacobs L, Schwartz E, Sakai LY. Extracellular microfibrils (10 nm in diameter) are increased in focalized and systemic scleroderma skin. Lab Invest. 1991;64:791-798.
27. Streeten BW, Licari PA. The zonules and the elastic microfibrillar system in the ciliary body. Invest Ophthalmol Vis Sci. 1983;24:667-681.
28. Garner A, Alexander RA. Pseudoexfoliative disease: Histochemical evidence of an affinity with zonular fibres. Br J Ophthalmol. 1984;68:574-580.
29. Shuttleworth CA, Berry L, Kielty CM. Microfibrillar components in dental pulp: Presence of both type VI collagen- and fibrillin-containing microfibrils. Arch Oral Biol. 1992;37:1079-1084.
30. Rohen JW, Futa R, Lütjen-Drecoll E. The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sections. Invest Ophthalmol Vis Sci. 1981;21:574-585.
31. Bernstein EF, Chen YQ, Tamai K, et al. Enhanced elastin and fibrillin gene expression in chronically photodamaged skin. J Invest Dermatol. 1994;103:182-186.
32. Hollister DW, Godfrey M, Sakai LY, Pyeritz RE. Immunohistologic abnormalities of the microfibrillar fiber system in the Marian syndrome. N Engl J Med. 1990;323:152-159.
33. McGookey Milewicz D, Pyeritz RE, Crawford ES, Byers PH. Marfan syndrome: Defective synthesis, secretion, and extracellular matrix formation of fibrillin by cultured dermal fibroblasts. J Clin Invest. 1992;89:79-86.
34. Dietz HC, Cutting GR, Pyeritz RE, et al. Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. Nature. 1991;352:337-339.
35. Tsipouras P, Del Mastro R, Sarfarazi M, et al. Linkage analysis demonstrates that Marfan syndrome, dominant ectopia lentis, and congenital contractural arachnodactyly are linked to the fibrillin genes on chromosomes 15 and 5. N Engl J Med. 1992;326:905-909.
36. Bartholomew RS. Lens displacement associated with pseudocapsular exfoliation. Br J Ophthalmol. 1970;54:744-750.
37. Naumann GOH, Küchle M, Schönherr U, "Erlanger Augenblätter-Gruppe." Pseudoexfoliations-syndrom als Risikofaktor für Glaskörperverlust bei der extrakapsulären Kataraktextraktion. Fortschr Ophthalmol. 1989;86:543-545.
38. Freissler K, Küchle M, Naumann GOH. Spontaneous dislocation of the lens in pseudoexfoliation syndrome. Arch Ophthalmol. 1995;113:1095.
39. Takei Y, Mizuno K. Electron-microscopic study of pseudo-exfoliation of the lens capsule. Graefes Arch Clin Exp Ophthalmol. 1978;205:213-220.
40. Chijiiwa T, Araki H, Ishibashi T, Inomata H. Degeneration of zonular fibrils in a case of exfoliation glaucoma. Ophthalmologica. 1989;199:16-23.
41. Futa R, Furuyoshi N. Phakodonesis in capsular glaucoma: A clinical and electron microscopic study. Jpn J Ophthalmol. 1989;33:311-317.
42. Streeten BW. Aberrant synthesis and aggregation of elastic tissue components in pseudoexfoliative fibrillopathy: A unifying concept. New Trends Ophthalmol. 1993;8:187-196.
43. Roh YB, Ishibashi T, Ito N, Inomata H. Alteration of microfibrils in the conjunctiva of patients with exfoliation syndrome. Arch Ophthalmol. 1987;105:978-982.
44. Streeten BW, Dark AJ, Barnes CW. Pseudoexfoliative material and oxytalan fibers. Exp Eye Res. 1984;38:523-531.
45. Ringvold A. A preliminary report on the amino acid composition of the pseudo-exfoliation material (PE material). Exp Eye Res. 1973;15:37-42.
46. Netland PA, Ye H, Streeten BW, Hernandez MR. Elastosis of the lamina cribrosa in pseudoexfoliation syndrome with glaucoma. Ophthalmology. 1995;102:878-886.
47. Schlötzer-Schrehardt U, Küchle M, Dörfler S, Naumann GOH. Pseudoexfoliative material in the eyelid skin of pseudoexfoliation-suspect patients: A clinicohistopathologic correlation. Ger J Ophthalmol. 1993;2:51-60.
48. Vogiatzis A, Marshall GE, Konstas AGP, Lee WR, Immunogold study of non-collagenous matrix components in normal and exfoliative iris. Br J Ophthalmol. 1994;78:850-858.
49. Streeten BW, Li Z-Y, Wallace RN, Maumenee IH, Yanoff M. The ocular zonule in Marfan's syndrome. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1990;31:S102.
50. Schlötzer-Schrehardt U, Naumann GOH. Trabecular meshwork in pseudoexfoliation syndrome with and without open-angle glaucoma. Invest (Ophthalmol Vis Sci. 1995;36:1750-1764.
51. Streeten BW, Gibson SA, Li Z. Lectin binding to pseudoexfoliative material and the ocular zonules. Invest Ophthalmol Vis Sci. 1986;27:1516-1521.
52. Hietanen J, Tarkkanen A. Glycoconjugates in exfoliation syndrome: A lectin histochemical study of the ciliary body and lens. Acta Ophthalmol Scand. 1989;67:288-294.
53. Asano N, Schlotzer-Schrehardt U, Naumann GOH. A histopathologic study of iris changes in pseudoexfoliation syndrome. Ophthalmology. 1995;102:1279-1290.
54. Schlötzer-Schrehardt U, Naumann GOH. Localization of proteolytic enzymes in the trabecular meshwork of pseudoexfoliation eyes. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1995;36:S329.