Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinase inhibitory activities, but affect cell adhesion to the extracellular matrix

Matrix Biology

Volumn 21, Issue 1, 2002, Pages 75-88

  Yeow, Karen M ^a   Kishnani, Narendra S ^b   Hutton, Mike ^a   Hawkes, Susan P ^b   Murphy, Gillian ^a   Edwards, Dylan R ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Matrix metalloproteinase; Reverse zymography; Sorsby's fundus dystrophy; Tissue inhibitor of metalloproteinase (TIMP)

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE; GELATINASE A; GELATINASE B; GELATINASE INHIBITOR; MATRIX METALLOPROTEINASE; MUTANT PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4;

ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BLINDNESS; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL SECRETION; CELL STRAIN BHK; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME KINETICS; EXTRACELLULAR MATRIX; EYE FUNDUS; GENE MUTATION; GENETIC LINKAGE; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; RETINA DEGENERATION; SORSBY FUNDUS DYSTROPHY; ZYMOGRAPHY;

ANIMALS; CELL ADHESION; CELL LINE; CLONING, MOLECULAR; CRICETINAE; CYTOSKELETON; EXTRACELLULAR MATRIX; MACULAR DEGENERATION; MATRIX METALLOPROTEINASES; MICROFILAMENTS; MUTATION; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

CRICETINAE;

EID: 0036154168     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(01)00180-9     Document Type: Article

References (53)

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