-
1
-
-
70350482699
-
Cellular and systemic effects of anthrax lethal toxin and edema toxin
-
M. Moayeri and S. H. Leppla: Cellular and systemic effects of anthrax lethal toxin and edema toxin. Mol.Aspects Med., 30(6), 439-455 (2009)
-
(2009)
Mol.Aspects Med.
, vol.30
, Issue.6
, pp. 439-455
-
-
Moayeri, M.1
Leppla, S.H.2
-
2
-
-
12144288811
-
Lethality during continuous anthrax lethal toxin infusion is associated with circulatory shock but not inflammatory cytokine or nitric oxide release in rats
-
X. Cui, M. Moayeri, Y. Li, X. Li, M. Haley, Y. Fitz, R. Correa-Araujo, S. M. Banks, S. H. Leppla and P. Q. Eichacker: Lethality during continuous anthrax lethal toxin infusion is associated with circulatory shock but not inflammatory cytokine or nitric oxide release in rats. Am.J.Physiol Regul.Integr.Comp Physiol, 286(4), R699-R709 (2004)
-
(2004)
Am.J.Physiol Regul.Integr.Comp Physiol
, vol.286
, Issue.4
-
-
Cui, X.1
Moayeri, M.2
Li, Y.3
Li, X.4
Haley, M.5
Fitz, Y.6
Correa-Araujo, R.7
Banks, S.M.8
Leppla, S.H.9
Eichacker, P.Q.10
-
3
-
-
25444447355
-
Pathophysiological manifestations in mice exposed to anthrax lethal toxin
-
N. C. Culley, D. M. Pinson, A. Chakrabarty, M. S. Mayo and S. M. Levine: Pathophysiological manifestations in mice exposed to anthrax lethal toxin. Infect.Immun., 73(10), 7006-7010 (2005)
-
(2005)
Infect.Immun.
, vol.73
, Issue.10
, pp. 7006-7010
-
-
Culley, N.C.1
Pinson, D.M.2
Chakrabarty, A.3
Mayo, M.S.4
Levine, S.M.5
-
4
-
-
33746596119
-
Sepsis and pathophysiology of anthrax in a nonhuman primate model
-
D. J. Stearns-Kurosawa, F. Lupu, F. B. Taylor, Jr., G. Kinasewitz and S. Kurosawa: Sepsis and pathophysiology of anthrax in a nonhuman primate model. Am J Pathol, 169(2), 433-44 (2006)
-
(2006)
Am J Pathol
, vol.169
, Issue.2
, pp. 433-444
-
-
Stearns-Kurosawa, D.J.1
Lupu, F.2
Taylor Jr., F.B.3
Kinasewitz, G.4
Kurosawa, S.5
-
5
-
-
0035039617
-
Quantitative pathology of inhalational anthrax I: Quantitative microscopic findings
-
L. M. Grinberg, F. A. Abramova, O. V. Yampolskaya, D. H. Walker and J. H. Smith: Quantitative pathology of inhalational anthrax I: quantitative microscopic findings. Mod.Pathol., 14(5), 482-495 (2001)
-
(2001)
Mod.Pathol.
, vol.14
, Issue.5
, pp. 482-495
-
-
Grinberg, L.M.1
Abramova, F.A.2
Yampolskaya, O.V.3
Walker, D.H.4
Smith, J.H.5
-
6
-
-
84904486743
-
Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage
-
S. R. Kuo, M. C. Willingham, S. H. Bour, E. A. Andreas, S. K. Park, C. Jackson, N. S. Duesbery, S. H. Leppla, W. J. Tang and A. E. Frankel: Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage. Microb.Pathog. (2007)
-
(2007)
Microb.Pathog.
-
-
Kuo, S.R.1
Willingham, M.C.2
Bour, S.H.3
Andreas, E.A.4
Park, S.K.5
Jackson, C.6
Duesbery, N.S.7
Leppla, S.H.8
Tang, W.J.9
Frankel, A.E.10
-
7
-
-
0035202697
-
Bioterrorism-related inhalational anthrax: The first 10 cases reported in the United States
-
J. A. Jernigan, D. S. Stephens, D. A. Ashford, C. Omenaca, M. S. Topiel, M. Galbraith, M. Tapper, T. L. Fisk, S. Zaki, T. Popovic, R. F. Meyer, C. P. Quinn, S. A. Harper, S. K. Fridkin, J. J. Sejvar, C. W. Shepard, M. McConnell, J. Guarner, W. J. Shieh, J. M. Malecki, J. L. Gerberding, J. M. Hughes and B. A. Perkins: Bioterrorism-related inhalational anthrax: the first 10 cases reported in the United States. Emerg.Infect.Dis., 7(6), 933-944 (2001)
-
(2001)
Emerg.Infect.Dis.
, vol.7
, Issue.6
, pp. 933-944
-
-
Jernigan, J.A.1
Stephens, D.S.2
Ashford, D.A.3
Omenaca, C.4
Topiel, M.S.5
Galbraith, M.6
Tapper, M.7
Fisk, T.L.8
Zaki, S.9
Popovic, T.10
Meyer, R.F.11
Quinn, C.P.12
Harper, S.A.13
Fridkin, S.K.14
Sejvar, J.J.15
Shepard, C.W.16
McConnell, M.17
Guarner, J.18
Shieh, W.J.19
Malecki, J.M.20
Gerberding, J.L.21
Hughes, J.M.22
Perkins, B.A.23
more..
-
8
-
-
0037138785
-
Fatal inhalational anthrax with unknown source of exposure in a 61-year-old woman in New York City
-
B. Mina, J. P. Dym, F. Kuepper, R. Tso, C. Arrastia, I. Kaplounova, H. Faraj, A. Kwapniewski, C. M. Krol, M. Grosser, J. Glick, S. Fochios, A. Remolina, L. Vasovic, J. Moses, T. Robin, M. DeVita and M. L. Tapper: Fatal inhalational anthrax with unknown source of exposure in a 61-year-old woman in New York City. JAMA, 287(7), 858-62 (2002)
-
(2002)
JAMA
, vol.287
, Issue.7
, pp. 858-862
-
-
Mina, B.1
Dym, J.P.2
Kuepper, F.3
Tso, R.4
Arrastia, C.5
Kaplounova, I.6
Faraj, H.7
Kwapniewski, A.8
Krol, C.M.9
Grosser, M.10
Glick, J.11
Fochios, S.12
Remolina, A.13
Vasovic, L.14
Moses, J.15
Robin, T.16
DeVita, M.17
Tapper, M.L.18
-
9
-
-
0042845996
-
Pathology and pathogenesis of bioterrorism-related inhalational anthrax
-
J. Guarner, J. A. Jernigan, W. J. Shieh, K. Tatti, L. M. Flannagan, D. S. Stephens, T. Popovic, D. A. Ashford, B. A. Perkins and S. R. Zaki: Pathology and pathogenesis of bioterrorism-related inhalational anthrax. Am J Pathol, 163(2), 701-9 (2003)
-
(2003)
Am J Pathol
, vol.163
, Issue.2
, pp. 701-709
-
-
Guarner, J.1
Jernigan, J.A.2
Shieh, W.J.3
Tatti, K.4
Flannagan, L.M.5
Stephens, D.S.6
Popovic, T.7
Ashford, D.A.8
Perkins, B.A.9
Zaki, S.R.10
-
10
-
-
0038303163
-
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor
-
H. M. Scobie, G. J. Rainey, K. A. Bradley and J. A. Young: Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc Natl Acad Sci U S A, 100(9), 5170-4 (2003)
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, Issue.9
, pp. 5170-5174
-
-
Scobie, H.M.1
Rainey, G.J.2
Bradley, K.A.3
Young, J.A.4
-
11
-
-
0035829509
-
Identification of the cellular receptor for anthrax toxin
-
K. A. Bradley, J. Mogridge, M. Mourez, R. J. Collier and J. A. Young: Identification of the cellular receptor for anthrax toxin. Nature, 414(6860), 225-9 (2001)
-
(2001)
Nature
, vol.414
, Issue.6860
, pp. 225-229
-
-
Bradley, K.A.1
Mogridge, J.2
Mourez, M.3
Collier, R.J.4
Young, J.A.5
-
12
-
-
0037076364
-
The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen
-
J. Mogridge, K. Cunningham, D. B. Lacy, M. Mourez and R. J. Collier: The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen. Proc Natl Acad Sci U S A, 99(10), 7045-8 (2002)
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.10
, pp. 7045-7048
-
-
Mogridge, J.1
Cunningham, K.2
Lacy, D.B.3
Mourez, M.4
Collier, R.J.5
-
13
-
-
69949172313
-
Identification of linear epitopes in Bacillus anthracis protective antigen bound by neutralizing antibodies
-
N. Abboud, M. De Jesus, A. Nakouzi, R. J. Cordero, M. Pujato, A. Fiser, J. Rivera and A. Casadevall: Identification of linear epitopes in Bacillus anthracis protective antigen bound by neutralizing antibodies. The Journal of biological chemistry, 284(37), 25077-86 (2009)
-
(2009)
The Journal of Biological Chemistry
, vol.284
, Issue.37
, pp. 25077-25086
-
-
Abboud, N.1
De Jesus, M.2
Nakouzi, A.3
Cordero, R.J.4
Pujato, M.5
Fiser, A.6
Rivera, J.7
Casadevall, A.8
-
14
-
-
27244439667
-
Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design
-
V. A. Karginov, E. M. Nestorovich, M. Moayeri, S. H. Leppla and S. M. Bezrukov: Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design. Proc Natl Acad Sci U S A, 102(42), 15075-80 (2005)
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, Issue.42
, pp. 15075-15080
-
-
Karginov, V.A.1
Nestorovich, E.M.2
Moayeri, M.3
Leppla, S.H.4
Bezrukov, S.M.5
-
15
-
-
16344366178
-
Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences
-
C. Kim, N. Gajendran, H. W. Mittrucker, M. Weiwad, Y. H. Song, R. Hurwitz, M. Wilmanns, G. Fischer and S. H. Kaufmann: Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences. Proc Natl Acad Sci U S A, 102(13), 4830-5 (2005)
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, Issue.13
, pp. 4830-4835
-
-
Kim, C.1
Gajendran, N.2
Mittrucker, H.W.3
Weiwad, M.4
Song, Y.H.5
Hurwitz, R.6
Wilmanns, M.7
Fischer, G.8
Kaufmann, S.H.9
-
16
-
-
20344391159
-
Anthrax lethal factor inhibition
-
W. L. Shoop, Y. Xiong, J. Wiltsie, A. Woods, J. Guo, J. V. Pivnichny, T. Felcetto, B. F. Michael, A. Bansal, R. T. Cummings, B. R. Cunningham, A. M. Friedlander, C. M. Douglas, S. B. Patel, D. Wisniewski, G. Scapin, S. P. Salowe, D. M. Zaller, K. T. Chapman, E. M. Scolnick, D. M. Schmatz, K. Bartizal, M. MacCoss and J. D. Hermes: Anthrax lethal factor inhibition. Proc Natl Acad Sci U S A, 102(22), 7958-63 (2005)
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, Issue.22
, pp. 7958-7963
-
-
Shoop, W.L.1
Xiong, Y.2
Wiltsie, J.3
Woods, A.4
Guo, J.5
Pivnichny, J.V.6
Felcetto, T.7
Michael, B.F.8
Bansal, A.9
Cummings, R.T.10
Cunningham, B.R.11
Friedlander, A.M.12
Douglas, C.M.13
Patel, S.B.14
Wisniewski, D.15
Scapin, G.16
Salowe, S.P.17
Zaller, D.M.18
Chapman, K.T.19
Scolnick, E.M.20
Schmatz, D.M.21
Bartizal, K.22
MacCoss, M.23
Hermes, J.D.24
more..
-
17
-
-
33748601221
-
Polyvalent inhibitors of anthrax toxin that target host receptors
-
S. Basha, P. Rai, V. Poon, A. Saraph, K. Gujraty, M. Y. Go, S. Sadacharan, M. Frost, J. Mogridge and R. S. Kane: Polyvalent inhibitors of anthrax toxin that target host receptors. Proc Natl Acad Sci U S A, 103(36), 13509-13 (2006)
-
(2006)
Proc Natl Acad Sci U S a
, vol.103
, Issue.36
, pp. 13509-13513
-
-
Basha, S.1
Rai, P.2
Poon, V.3
Saraph, A.4
Gujraty, K.5
Go, M.Y.6
Sadacharan, S.7
Frost, M.8
Mogridge, J.9
Kane, R.S.10
-
18
-
-
68149175255
-
Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo
-
S. Liu, D. Crown, S. Miller-Randolph, M. Moayeri, H. Wang, H. Hu, T. Morley and S. H. Leppla: Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo. Proc Natl Acad Sci U S A, 106(30), 12424-9 (2009)
-
(2009)
Proc Natl Acad Sci U S a
, vol.106
, Issue.30
, pp. 12424-12429
-
-
Liu, S.1
Crown, D.2
Miller-Randolph, S.3
Moayeri, M.4
Wang, H.5
Hu, H.6
Morley, T.7
Leppla, S.H.8
-
19
-
-
0028088404
-
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
-
K. R. Klimpel, N. Arora and S. H. Leppla: Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol.Microbiol., 13(6), 1093-1100 (1994)
-
(1994)
Mol.Microbiol.
, vol.13
, Issue.6
, pp. 1093-1100
-
-
Klimpel, K.R.1
Arora, N.2
Leppla, S.H.3
-
20
-
-
18244414803
-
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
-
N. S. Duesbery, C. P. Webb, S. H. Leppla, V. M. Gordon, K. R. Klimpel, T. D. Copeland, N. G. Ahn, M. K. Oskarsson, K. Fukasawa, K. D. Paull and G. F. Vande Woude: Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science, 280(5364), 734-7 (1998)
-
(1998)
Science
, vol.280
, Issue.5364
, pp. 734-737
-
-
Duesbery, N.S.1
Webb, C.P.2
Leppla, S.H.3
Gordon, V.M.4
Klimpel, K.R.5
Copeland, T.D.6
Ahn, N.G.7
Oskarsson, M.K.8
Fukasawa, K.9
Paull, K.D.10
Vande Woude, G.F.11
-
21
-
-
84869073837
-
Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages
-
K. A. Hellmich, J. L. Levinsohn, R. Fattah, Z. L. Newman, N. Maier, I. Sastalla, S. Liu, S. H. Leppla and M. Moayeri: Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages. PLoS One, 7(11), e49741 (2012)
-
(2012)
PLoS One
, vol.7
, Issue.11
-
-
Hellmich, K.A.1
Levinsohn, J.L.2
Fattah, R.3
Newman, Z.L.4
Maier, N.5
Sastalla, I.6
Liu, S.7
Leppla, S.H.8
Moayeri, M.9
-
22
-
-
1242351553
-
The roles of anthrax toxin in pathogenesis
-
M. Moayeri and S. H. Leppla: The roles of anthrax toxin in pathogenesis. Curr Opin Microbiol, 7(1), 19-24 (2004)
-
(2004)
Curr Opin Microbiol
, vol.7
, Issue.1
, pp. 19-24
-
-
Moayeri, M.1
Leppla, S.H.2
-
23
-
-
0037022666
-
Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
-
H. M. Koo, M. VanBrocklin, M. J. McWilliams, S. H. Leppla, N. S. Duesbery and G. F. Vande Woude: Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase. Proc Natl Acad Sci U S A, 99(5), 3052-7 (2002)
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.5
, pp. 3052-3057
-
-
Koo, H.M.1
VanBrocklin, M.2
McWilliams, M.J.3
Leppla, S.H.4
Duesbery, N.S.5
Vande Woude, G.F.6
-
24
-
-
0037144590
-
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition
-
J. M. Park, F. R. Greten, Z. W. Li and M. Karin: Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science, 297(5589), 2048-51 (2002)
-
(2002)
Science
, vol.297
, Issue.5589
, pp. 2048-2051
-
-
Park, J.M.1
Greten, F.R.2
Li, Z.W.3
Karin, M.4
-
25
-
-
35348921181
-
Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo
-
N. H. Purcell, B. J. Wilkins, A. York, M. K. Saba-El-Leil, S. Meloche, J. Robbins and J. D. Molkentin: Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proc Natl Acad Sci U S A, 104(35), 14074-9 (2007)
-
(2007)
Proc Natl Acad Sci U S a
, vol.104
, Issue.35
, pp. 14074-14079
-
-
Purcell, N.H.1
Wilkins, B.J.2
York, A.3
Saba-El-Leil, M.K.4
Meloche, S.5
Robbins, J.6
Molkentin, J.D.7
-
27
-
-
11244260655
-
Anthrax lethal toxin: A weapon of multisystem destruction
-
A. Agrawal and B. Pulendran: Anthrax lethal toxin: a weapon of multisystem destruction. Cell Mol Life Sci, 61(22), 2859-65 (2004)
-
(2004)
Cell Mol Life Sci
, vol.61
, Issue.22
, pp. 2859-2865
-
-
Agrawal, A.1
Pulendran, B.2
-
28
-
-
1442348473
-
Immune system paralysis by anthrax lethal toxin: The roles of innate and adaptive immunity
-
T. Fukao: Immune system paralysis by anthrax lethal toxin: the roles of innate and adaptive immunity. Lancet Infect Dis, 4(3), 166-70 (2004)
-
(2004)
Lancet Infect Dis
, vol.4
, Issue.3
, pp. 166-170
-
-
Fukao, T.1
-
29
-
-
0014252017
-
Pathophysiological changes in the rat associated with anthrax toxin
-
D. C. Fish, F. Klein, R. E. Lincoln, J. S. Walker and J. P. Dobbs: Pathophysiological changes in the rat associated with anthrax toxin. The Journal of infectious diseases, 118(1), 114-24 (1968)
-
(1968)
The Journal of Infectious Diseases
, vol.118
, Issue.1
, pp. 114-124
-
-
Fish, D.C.1
Klein, F.2
Lincoln, R.E.3
Walker, J.S.4
Dobbs, J.P.5
-
30
-
-
0014252491
-
Neurological and physiological responses of the primate to anthrax toxin
-
J. A. Vick, R. E. Lincoln, F. Klein, B. G. Mahlandt, J. S. Walker and D. C. Fish: Neurological and physiological responses of the primate to anthrax toxin. The Journal of infectious diseases, 118(1), 85-96 (1968)
-
(1968)
The Journal of Infectious Diseases
, vol.118
, Issue.1
, pp. 85-96
-
-
Vick, J.A.1
Lincoln, R.E.2
Klein, F.3
Mahlandt, B.G.4
Walker, J.S.5
Fish, D.C.6
-
31
-
-
27544500820
-
Bacillus anthracis edema toxin causes extensive tissue lesions and rapid lethality in mice
-
A. M. Firoved, G. F. Miller, M. Moayeri, R. Kakkar, Y. Shen, J. F. Wiggins, E. M. McNally, W. J. Tang and S. H. Leppla: Bacillus anthracis edema toxin causes extensive tissue lesions and rapid lethality in mice. Am J Pathol, 167(5), 1309-20 (2005)
-
(2005)
Am J Pathol
, vol.167
, Issue.5
, pp. 1309-1320
-
-
Firoved, A.M.1
Miller, G.F.2
Moayeri, M.3
Kakkar, R.4
Shen, Y.5
Wiggins, J.F.6
McNally, E.M.7
Tang, W.J.8
Leppla, S.H.9
-
32
-
-
85047692288
-
Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice
-
M. Moayeri, D. Haines, H. A. Young and S. H. Leppla: Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice. J.Clin.Invest, 112(5), 670-682 (2003)
-
(2003)
J.Clin.Invest
, vol.112
, Issue.5
, pp. 670-682
-
-
Moayeri, M.1
Haines, D.2
Young, H.A.3
Leppla, S.H.4
-
33
-
-
34347214064
-
Lethal and edema toxins of anthrax induce distinct hemodynamic dysfunction
-
L. E. Watson, J. Mock, H. Lal, G. Lu, R. W. Bourdeau, W. J. Tang, S. H. Leppla, D. E. Dostal and A. E. Frankel: Lethal and edema toxins of anthrax induce distinct hemodynamic dysfunction. Front Biosci., 12, 4670-4675 (2007)
-
(2007)
Front Biosci.
, vol.12
, pp. 4670-4675
-
-
Watson, L.E.1
Mock, J.2
Lal, H.3
Lu, G.4
Bourdeau, R.W.5
Tang, W.J.6
Leppla, S.H.7
Dostal, D.E.8
Frankel, A.E.9
-
34
-
-
84883742626
-
Key tissue targets responsible for anthrax-toxin-induced lethality
-
S. Liu, Y. Zhang, M. Moayeri, J. Liu, D. Crown, R. J. Fattah, A. N. Wein, Z. X. Yu, T. Finkel and S. H. Leppla: Key tissue targets responsible for anthrax-toxin-induced lethality. Nature, 501(7465), 63-8 (2013)
-
(2013)
Nature
, vol.501
, Issue.7465
, pp. 63-68
-
-
Liu, S.1
Zhang, Y.2
Moayeri, M.3
Liu, J.4
Crown, D.5
Fattah, R.J.6
Wein, A.N.7
Yu, Z.X.8
Finkel, T.9
Leppla, S.H.10
-
35
-
-
3242678060
-
Knock-on effect of anthrax lethal toxin on macrophages potentiates cytotoxicity to endothelial cells
-
J. Pandey and D. Warburton: Knock-on effect of anthrax lethal toxin on macrophages potentiates cytotoxicity to endothelial cells. Microbes.Infect., 6(9), 835-843 (2004)
-
(2004)
Microbes.Infect.
, vol.6
, Issue.9
, pp. 835-843
-
-
Pandey, J.1
Warburton, D.2
-
36
-
-
0346251030
-
Anthrax lethal toxin induces human endothelial cell apoptosis
-
J. E. Kirby: Anthrax lethal toxin induces human endothelial cell apoptosis. Infect.Immun., 72(1), 430-439 (2004)
-
(2004)
Infect.Immun.
, vol.72
, Issue.1
, pp. 430-439
-
-
Kirby, J.E.1
-
37
-
-
40649088321
-
Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature
-
R. E. Bolcome, 3rd, S. E. Sullivan, R. Zeller, A. P. Barker, R. J. Collier and J. Chan: Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature. Proc Natl Acad Sci U S A, 105(7), 2439-44 (2008)
-
(2008)
Proc Natl Acad Sci U S a
, vol.105
, Issue.7
, pp. 2439-2444
-
-
Bolcome III, R.E.1
Sullivan, S.E.2
Zeller, R.3
Barker, A.P.4
Collier, R.J.5
Chan, J.6
-
38
-
-
84880171842
-
B. anthracis edema toxin increases cAMP levels and inhibits phenylephrine-stimulated contraction in a rat aortic ring model
-
Y. Li, X. Cui, S. B. Solomon, K. Remy, Y. Fitz and P. Q. Eichacker: B. anthracis edema toxin increases cAMP levels and inhibits phenylephrine- stimulated contraction in a rat aortic ring model. Am J Physiol Heart Circ Physiol, 305(2), H238-50 (2013)
-
(2013)
Am J Physiol Heart Circ Physiol
, vol.305
, Issue.2
-
-
Li, Y.1
Cui, X.2
Solomon, S.B.3
Remy, K.4
Fitz, Y.5
Eichacker, P.Q.6
-
39
-
-
42649102509
-
Anthrax toxins induce shock in rats by depressed cardiac ventricular function
-
L. E. Watson, S. R. Kuo, K. Katki, T. Dang, S. K. Park, D. E. Dostal, W. J. Tang, S. H. Leppla and A. E. Frankel: Anthrax toxins induce shock in rats by depressed cardiac ventricular function. PLoS.ONE., 2(5), e466 (2007)
-
(2007)
PLoS.ONE.
, vol.2
, Issue.5
-
-
Watson, L.E.1
Kuo, S.R.2
Katki, K.3
Dang, T.4
Park, S.K.5
Dostal, D.E.6
Tang, W.J.7
Leppla, S.H.8
Frankel, A.E.9
-
40
-
-
33846811743
-
Bacillus anthracis edema and lethal toxin have different hemodynamic effects but function together to worsen shock and outcome in a rat model
-
doi:10.1086/510856
-
X. Cui, Y. Li, X. Li, M. W. Laird, M. Subramanian, M. Moayeri, S. H. Leppla, Y. Fitz, J. Su, K. Sherer and P. Q. Eichacker: Bacillus anthracis edema and lethal toxin have different hemodynamic effects but function together to worsen shock and outcome in a rat model. The Journal of infectious diseases, 195(4), 572-80 (2007) doi:10.1086/510856
-
(2007)
The Journal of Infectious Diseases
, vol.195
, Issue.4
, pp. 572-580
-
-
Cui, X.1
Li, Y.2
Li, X.3
Laird, M.W.4
Subramanian, M.5
Moayeri, M.6
Leppla, S.H.7
Fitz, Y.8
Su, J.9
Sherer, K.10
Eichacker, P.Q.11
-
41
-
-
84855906688
-
New insights into the biological effects of anthrax toxins: Linking cellular to organismal responses
-
doi:10.1016/j.micinf.2011.08.016
-
A. Guichard, V. Nizet and E. Bier: New insights into the biological effects of anthrax toxins: linking cellular to organismal responses. Microbes Infect, 14(2), 97-118 (2012) doi:10.1016/j.micinf.2011.08.016
-
(2012)
Microbes Infect
, vol.14
, Issue.2
, pp. 97-118
-
-
Guichard, A.1
Nizet, V.2
Bier, E.3
-
42
-
-
79959665472
-
Hemodynamic effects of anthrax toxins in the rabbit model and the cardiac pathology induced by lethal toxin
-
W. S. Lawrence, J. R. Marshall, D. L. Zavala, L. E. Weaver, W. B. Baze, S. T. Moen, E. B. Whorton, R. L. Gourley and J. W. Peterson: Hemodynamic effects of anthrax toxins in the rabbit model and the cardiac pathology induced by lethal toxin. Toxins (Basel), 3(6), 721-36 (2011)
-
(2011)
Toxins (Basel)
, vol.3
, Issue.6
, pp. 721-736
-
-
Lawrence, W.S.1
Marshall, J.R.2
Zavala, D.L.3
Weaver, L.E.4
Baze, W.B.5
Moen, S.T.6
Whorton, E.B.7
Gourley, R.L.8
Peterson, J.W.9
-
43
-
-
78650395903
-
Anthrax lethal and edema toxins produce different patterns of cardiovascular and renal dysfunction and synergistically decrease survival in canines
-
D. A. Sweeney, X. Cui, S. B. Solomon, D. A. Vitberg, T. S. Migone, D. Scher, R. L. Danner, C. Natanson, G. M. Subramanian and P. Q. Eichacker: Anthrax lethal and edema toxins produce different patterns of cardiovascular and renal dysfunction and synergistically decrease survival in canines. J Infect Dis, 202(12), 1885-96 (2010)
-
(2010)
J Infect Dis
, vol.202
, Issue.12
, pp. 1885-1896
-
-
Sweeney, D.A.1
Cui, X.2
Solomon, S.B.3
Vitberg, D.A.4
Migone, T.S.5
Scher, D.6
Danner, R.L.7
Natanson, C.8
Subramanian, G.M.9
Eichacker, P.Q.10
-
44
-
-
34250737810
-
New insights into the pathogenesis and treatment of anthrax toxin-induced shock
-
Y. Li, K. Sherer, X. Cui and P. Q. Eichacker: New insights into the pathogenesis and treatment of anthrax toxin-induced shock. Expert Opin Biol Ther, 7(6), 843-54 (2007)
-
(2007)
Expert Opin Biol Ther
, vol.7
, Issue.6
, pp. 843-854
-
-
Li, Y.1
Sherer, K.2
Cui, X.3
Eichacker, P.Q.4
-
45
-
-
0035965626
-
Death due to bioterrorism-related inhalational anthrax: Report of 2 patients
-
L. Borio, D. Frank, V. Mani, C. Chiriboga, M. Pollanen, M. Ripple, S. Ali, C. DiAngelo, J. Lee, J. Arden, J. Titus, D. Fowler, T. O'Toole, H. Masur, J. Bartlett and T. Inglesby: Death due to bioterrorism-related inhalational anthrax: report of 2 patients. JAMA, 286(20), 2554-9 (2001)
-
(2001)
JAMA
, vol.286
, Issue.20
, pp. 2554-2559
-
-
Borio, L.1
Frank, D.2
Mani, V.3
Chiriboga, C.4
Pollanen, M.5
Ripple, M.6
Ali, S.7
DiAngelo, C.8
Lee, J.9
Arden, J.10
Titus, J.11
Fowler, D.12
O'Toole, T.13
Masur, H.14
Bartlett, J.15
Inglesby, T.16
-
46
-
-
19544371576
-
Anthrax lethal toxin induces endothelial barrier dysfunction
-
J. M. Warfel, A. D. Steele and F. D'Agnillo: Anthrax lethal toxin induces endothelial barrier dysfunction. Am J Pathol, 166(6), 1871-81 (2005)
-
(2005)
Am J Pathol
, vol.166
, Issue.6
, pp. 1871-1881
-
-
Warfel, J.M.1
Steele, A.D.2
D'Agnillo, F.3
-
47
-
-
84876518622
-
Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions
-
F. D'Agnillo, M. C. Williams, M. Moayeri and J. M. Warfel: Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions. PLoS One, 8(4), e62576 (2013)
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
D'Agnillo, F.1
Williams, M.C.2
Moayeri, M.3
Warfel, J.M.4
-
48
-
-
31844441582
-
Anthrax lethal toxin induces ketotifen-sensitive intradermal vascular leakage in certain inbred mice
-
Y. Gozes, M. Moayeri, J. F. Wiggins and S. H. Leppla: Anthrax lethal toxin induces ketotifen-sensitive intradermal vascular leakage in certain inbred mice. Infect Immun, 74(2), 1266-72 (2006)
-
(2006)
Infect Immun
, vol.74
, Issue.2
, pp. 1266-1272
-
-
Gozes, Y.1
Moayeri, M.2
Wiggins, J.F.3
Leppla, S.H.4
-
49
-
-
84855725698
-
Anthrax lethal toxin disrupts the endothelial permeability barrier through blocking p38 signaling
-
T. Liu, E. Milia, R. R. Warburton, N. S. Hill, M. Gaestel and U. S. Kayyali: Anthrax lethal toxin disrupts the endothelial permeability barrier through blocking p38 signaling. J Cell Physiol, 227(4), 1438-45 (2012)
-
(2012)
J Cell Physiol
, vol.227
, Issue.4
, pp. 1438-1445
-
-
Liu, T.1
Milia, E.2
Warburton, R.R.3
Hill, N.S.4
Gaestel, M.5
Kayyali, U.S.6
-
50
-
-
25844500354
-
Antiplatelet activities of anthrax lethal toxin are associated with suppressed p42/44 and p38 mitogen-activated protein kinase pathways in the platelets
-
J. H. Kau, D. S. Sun, W. J. Tsai, H. F. Shyu, H. H. Huang, H. C. Lin and H. H. Chang: Antiplatelet activities of anthrax lethal toxin are associated with suppressed p42/44 and p38 mitogen-activated protein kinase pathways in the platelets. J.Infect.Dis., 192(8), 1465-1474 (2005)
-
(2005)
J.Infect.Dis.
, vol.192
, Issue.8
, pp. 1465-1474
-
-
Kau, J.H.1
Sun, D.S.2
Tsai, W.J.3
Shyu, H.F.4
Huang, H.H.5
Lin, H.C.6
Chang, H.H.7
-
51
-
-
28144431782
-
Inhibition of platelet aggregation by anthrax edema toxin
-
S. Alam, M. Gupta and R. Bhatnagar: Inhibition of platelet aggregation by anthrax edema toxin. Biochem Biophys Res Commun, 339(1), 107-14 (2006)
-
(2006)
Biochem Biophys Res Commun
, vol.339
, Issue.1
, pp. 107-114
-
-
Alam, S.1
Gupta, M.2
Bhatnagar, R.3
-
52
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
E. D. Boyden and W. F. Dietrich: Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat.Genet., 38(2), 240-244 (2006)
-
(2006)
Nat.Genet.
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
53
-
-
78651258397
-
Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment
-
doi:10.1371/journal.ppat.1001222
-
M. Moayeri, D. Crown, Z. L. Newman, S. Okugawa, M. Eckhaus, C. Cataisson, S. Liu, I. Sastalla and S. H. Leppla: Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment. PLoS Pathog, 6(12), e1001222 (2010) doi:10.1371/journal.ppat. 1001222
-
(2010)
PLoS Pathog
, vol.6
, Issue.12
-
-
Moayeri, M.1
Crown, D.2
Newman, Z.L.3
Okugawa, S.4
Eckhaus, M.5
Cataisson, C.6
Liu, S.7
Sastalla, I.8
Leppla, S.H.9
-
54
-
-
84861214708
-
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
-
doi:10.1371/journal.ppat.1002638
-
J. L. Levinsohn, Z. L. Newman, K. A. Hellmich, R. Fattah, M. A. Getz, S. Liu, I. Sastalla, S. H. Leppla and M. Moayeri: Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome. PLoS Pathog, 8(3), e1002638 (2012) doi:10.1371/journal.ppat.1002638
-
(2012)
PLoS Pathog
, vol.8
, Issue.3
-
-
Levinsohn, J.L.1
Newman, Z.L.2
Hellmich, K.A.3
Fattah, R.4
Getz, M.A.5
Liu, S.6
Sastalla, I.7
Leppla, S.H.8
Moayeri, M.9
-
55
-
-
11844262784
-
Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists
-
doi:10.1084/jem.20041215
-
J. M. Park, V. H. Ng, S. Maeda, R. F. Rest and M. Karin: Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists. J Exp Med, 200(12), 1647-55 (2004) doi:10.1084/jem.20041215
-
(2004)
J Exp Med
, vol.200
, Issue.12
, pp. 1647-1655
-
-
Park, J.M.1
Ng, V.H.2
Maeda, S.3
Rest, R.F.4
Karin, M.5
-
56
-
-
0035142005
-
Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin
-
doi:10.1128/IAI.69.2.1175-1177.2001
-
J. L. Erwin, L. M. DaSilva, S. Bavari, S. F. Little, A. M. Friedlander and T. C. Chanh: Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin. Infection and immunity, 69(2), 1175-7 (2001) doi:10.1128/IAI.69.2.1175-1177.2001
-
(2001)
Infection and Immunity
, vol.69
, Issue.2
, pp. 1175-1177
-
-
Erwin, J.L.1
DaSilva, L.M.2
Bavari, S.3
Little, S.F.4
Friedlander, A.M.5
Chanh, T.C.6
-
57
-
-
0032755353
-
Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha
-
R. Pellizzari, C. Guidi-Rontani, G. Vitale, M. Mock and C. Montecucco: Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha. FEBS Lett., 462(1-2), 199-204 (1999)
-
(1999)
FEBS Lett.
, vol.462
, Issue.1-2
, pp. 199-204
-
-
Pellizzari, R.1
Guidi-Rontani, C.2
Vitale, G.3
Mock, M.4
Montecucco, C.5
-
58
-
-
16244362671
-
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
-
S. L. Fink and B. T. Cookson: Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infection and immunity, 73(4), 1907-16 (2005)
-
(2005)
Infection and Immunity
, vol.73
, Issue.4
, pp. 1907-1916
-
-
Fink, S.L.1
Cookson, B.T.2
-
59
-
-
34848866958
-
Pyroptosis and host cell death responses during Salmonella infection
-
S. L. Fink and B. T. Cookson: Pyroptosis and host cell death responses during Salmonella infection. Cell Microbiol, 9(11), 2562-70 (2007)
-
(2007)
Cell Microbiol
, vol.9
, Issue.11
, pp. 2562-2570
-
-
Fink, S.L.1
Cookson, B.T.2
-
60
-
-
33749576792
-
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
-
S. L. Fink and B. T. Cookson: Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol, 8(11), 1812-25 (2006)
-
(2006)
Cell Microbiol
, vol.8
, Issue.11
, pp. 1812-1825
-
-
Fink, S.L.1
Cookson, B.T.2
-
61
-
-
0033679111
-
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation
-
P. J. Sansonetti, A. Phalipon, J. Arondel, K. Thirumalai, S. Banerjee, S. Akira, K. Takeda and A. Zychlinsky: Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity, 12(5), 581-90 (2000)
-
(2000)
Immunity
, vol.12
, Issue.5
, pp. 581-590
-
-
Sansonetti, P.J.1
Phalipon, A.2
Arondel, J.3
Thirumalai, K.4
Banerjee, S.5
Akira, S.6
Takeda, K.7
Zychlinsky, A.8
-
62
-
-
65449134828
-
Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila
-
C. L. Case, S. Shin and C. R. Roy: Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect Immun, 77(5), 1981-91 (2009)
-
(2009)
Infect Immun
, vol.77
, Issue.5
, pp. 1981-1991
-
-
Case, C.L.1
Shin, S.2
Roy, C.R.3
-
63
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
T. Suzuki, L. Franchi, C. Toma, H. Ashida, M. Ogawa, Y. Yoshikawa, H. Mimuro, N. Inohara, C. Sasakawa and G. Nunez: Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog, 3(8), e111 (2007)
-
(2007)
PLoS Pathog
, vol.3
, Issue.8
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
Ashida, H.4
Ogawa, M.5
Yoshikawa, Y.6
Mimuro, H.7
Inohara, N.8
Sasakawa, C.9
Nunez, G.10
-
64
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
S. Mariathasan, D. S. Weiss, V. M. Dixit and D. M. Monack: Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med, 202(8), 1043-9 (2005)
-
(2005)
J Exp Med
, vol.202
, Issue.8
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
65
-
-
25144521276
-
Caspase-1 dependent macrophage death induced by Burkholderia pseudomallei
-
G. W. Sun, J. Lu, S. Pervaiz, W. P. Cao and Y. H. Gan: Caspase-1 dependent macrophage death induced by Burkholderia pseudomallei. Cell Microbiol, 7(10), 1447-58 (2005)
-
(2005)
Cell Microbiol
, vol.7
, Issue.10
, pp. 1447-1458
-
-
Sun, G.W.1
Lu, J.2
Pervaiz, S.3
Cao, W.P.4
Gan, Y.H.5
-
66
-
-
77957279148
-
Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin
-
S. M. Muehlbauer, H. Lima, Jr., D. L. Goldman, L. S. Jacobson, J. Rivera, M. F. Goldberg, M. A. Palladino, A. Casadevall and J. Brojatsch: Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. The American journal of pathology, 177(2), 735-43 (2010)
-
(2010)
The American Journal of Pathology
, vol.177
, Issue.2
, pp. 735-743
-
-
Muehlbauer, S.M.1
Lima Jr., H.2
Goldman, D.L.3
Jacobson, L.S.4
Rivera, J.5
Goldberg, M.F.6
Palladino, M.A.7
Casadevall, A.8
Brojatsch, J.9
-
67
-
-
34047223819
-
Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis
-
S. M. Muehlbauer, T. H. Evering, G. Bonuccelli, R. C. Squires, A. W. Ashton, S. A. Porcelli, M. P. Lisanti and J. Brojatsch: Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis. Cell Cycle, 6(6), 758-766 (2007)
-
(2007)
Cell Cycle
, vol.6
, Issue.6
, pp. 758-766
-
-
Muehlbauer, S.M.1
Evering, T.H.2
Bonuccelli, G.3
Squires, R.C.4
Ashton, A.W.5
Porcelli, S.A.6
Lisanti, M.P.7
Brojatsch, J.8
-
68
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
F. S. Sutterwala, Y. Ogura, M. Szczepanik, M. Lara-Tejero, G. S. Lichtenberger, E. P. Grant, J. Bertin, A. J. Coyle, J. E. Galan, P. W. Askenase and R. A. Flavell: Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity, 24(3), 317-27 (2006)
-
(2006)
Immunity
, vol.24
, Issue.3
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galan, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
69
-
-
0029916522
-
Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone
-
L. P. Shornick, P. De Togni, S. Mariathasan, J. Goellner, J. Strauss-Schoenberger, R. W. Karr, T. A. Ferguson and D. D. Chaplin: Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone. J Exp Med, 183(4), 1427-36 (1996)
-
(1996)
J Exp Med
, vol.183
, Issue.4
, pp. 1427-1436
-
-
Shornick, L.P.1
De Togni, P.2
Mariathasan, S.3
Goellner, J.4
Strauss-Schoenberger, J.5
Karr, R.W.6
Ferguson, T.A.7
Chaplin, D.D.8
-
70
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
T. Kawai, O. Adachi, T. Ogawa, K. Takeda and S. Akira: Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity, 11(1), 115-22 (1999)
-
(1999)
Immunity
, vol.11
, Issue.1
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
71
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
S. Mariathasan, K. Newton, D. M. Monack, D. Vucic, D. M. French, W. P. Lee, M. Roose-Girma, S. Erickson and V. M. Dixit: Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature, 430(6996), 213-8 (2004)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
72
-
-
20144380566
-
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock
-
J. Sunden-Cullberg, A. Norrby-Teglund, A. Rouhiainen, H. Rauvala, G. Herman, K. J. Tracey, M. L. Lee, J. Andersson, L. Tokics and C. J. Treutiger: Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock. Crit Care Med, 33(3), 564-73 (2005)
-
(2005)
Crit Care Med
, vol.33
, Issue.3
, pp. 564-573
-
-
Sunden-Cullberg, J.1
Norrby-Teglund, A.2
Rouhiainen, A.3
Rauvala, H.4
Herman, G.5
Tracey, K.J.6
Lee, M.L.7
Andersson, J.8
Tokics, L.9
Treutiger, C.J.10
-
73
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
H. Wang, O. Bloom, M. Zhang, J. M. Vishnubhakat, M. Ombrellino, J. Che, A. Frazier, H. Yang, S. Ivanova, L. Borovikova, K. R. Manogue, E. Faist, E. Abraham, J. Andersson, U. Andersson, P. E. Molina, N. N. Abumrad, A. Sama and K. J. Tracey: HMG-1 as a late mediator of endotoxin lethality in mice. Science, 285(5425), 248-51 (1999)
-
(1999)
Science
, vol.285
, Issue.5425
, pp. 248-251
-
-
Wang, H.1
Bloom, O.2
Zhang, M.3
Vishnubhakat, J.M.4
Ombrellino, M.5
Che, J.6
Frazier, A.7
Yang, H.8
Ivanova, S.9
Borovikova, L.10
Manogue, K.R.11
Faist, E.12
Abraham, E.13
Andersson, J.14
Andersson, U.15
Molina, P.E.16
Abumrad, N.N.17
Sama, A.18
Tracey, K.J.19
-
74
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
doi:10.1038/nature00858
-
P. Scaffidi, T. Misteli and M. E. Bianchi: Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature, 418(6894), 191-5 (2002) doi:10.1038/nature00858
-
(2002)
Nature
, vol.418
, Issue.6894
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
75
-
-
0037099343
-
Effect of the lower molecular capsule released from the cell surface of Bacillus anthracis on the pathogenesis of anthrax
-
doi:10.1086/341299
-
S. Makino, M. Watarai, H. I. Cheun, T. Shirahata and I. Uchida: Effect of the lower molecular capsule released from the cell surface of Bacillus anthracis on the pathogenesis of anthrax. The Journal of infectious diseases, 186(2), 227-33 (2002) doi:10.1086/341299
-
(2002)
The Journal of Infectious Diseases
, vol.186
, Issue.2
, pp. 227-233
-
-
Makino, S.1
Watarai, M.2
Cheun, H.I.3
Shirahata, T.4
Uchida, I.5
-
76
-
-
0000059218
-
The chemical basis of the virulence of bacillus anthracis. II. Some biological properties of bacterial products
-
J. Keppie, H. Smith and P. W. Harris-Smith: The chemical basis of the virulence of bacillus anthracis. II. Some biological properties of bacterial products. Br J Exp Pathol, 34(5), 486-96 (1953)
-
(1953)
Br J Exp Pathol
, vol.34
, Issue.5
, pp. 486-496
-
-
Keppie, J.1
Smith, H.2
Harris-Smith, P.W.3
-
77
-
-
0021879151
-
Demonstration of a capsule plasmid in Bacillus anthracis
-
B. D. Green, L. Battisti, T. M. Koehler, C. B. Thorne and B. E. Ivins: Demonstration of a capsule plasmid in Bacillus anthracis. Infect Immun, 49(2), 291-7 (1985)
-
(1985)
Infect Immun
, vol.49
, Issue.2
, pp. 291-297
-
-
Green, B.D.1
Battisti, L.2
Koehler, T.M.3
Thorne, C.B.4
Ivins, B.E.5
-
78
-
-
40549145143
-
Treatment of experimental anthrax with recombinant capsule depolymerase
-
A. Scorpio, S. A. Tobery, W. J. Ribot and A. M. Friedlander: Treatment of experimental anthrax with recombinant capsule depolymerase. Antimicrob Agents Chemother, 52(3), 1014-20 (2008)
-
(2008)
Antimicrob Agents Chemother
, vol.52
, Issue.3
, pp. 1014-1020
-
-
Scorpio, A.1
Tobery, S.A.2
Ribot, W.J.3
Friedlander, A.M.4
-
79
-
-
33845978057
-
Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule
-
T. R. Kozel, P. Thorkildson, S. Brandt, W. H. Welch, J. A. Lovchik, D. P. AuCoin, J. Vilai and C. R. Lyons: Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule. Infect Immun, 75(1), 152-63 (2007)
-
(2007)
Infect Immun
, vol.75
, Issue.1
, pp. 152-163
-
-
Kozel, T.R.1
Thorkildson, P.2
Brandt, S.3
Welch, W.H.4
Lovchik, J.A.5
AuCoin, D.P.6
Vilai, J.7
Lyons, C.R.8
-
80
-
-
84880162172
-
Bacillus anthracis Cell Wall Peptidoglycan but Not Lethal or Edema Toxins Produces Changes Consistent With Disseminated Intravascular Coagulation in a Rat Model
-
P. Qiu, Y. Li, J. Shiloach, X. Cui, J. Sun, L. Trinh, J. Kubler-Kielb, E. Vinogradov, H. Mani, M. Al-Hamad, Y. Fitz and P. Q. Eichacker: Bacillus anthracis Cell Wall Peptidoglycan but Not Lethal or Edema Toxins Produces Changes Consistent With Disseminated Intravascular Coagulation in a Rat Model. J Infect Dis, 208(6), 978-89 (2013)
-
(2013)
J Infect Dis
, vol.208
, Issue.6
, pp. 978-989
-
-
Qiu, P.1
Li, Y.2
Shiloach, J.3
Cui, X.4
Sun, J.5
Trinh, L.6
Kubler-Kielb, J.7
Vinogradov, E.8
Mani, H.9
Al-Hamad, M.10
Fitz, Y.11
Eichacker, P.Q.12
-
81
-
-
13444274668
-
Toll-like receptor downstream signaling
-
T. Kawai and S. Akira: Toll-like receptor downstream signaling. Arthritis Res Ther, 7(1), 12-9 (2005)
-
(2005)
Arthritis Res Ther
, vol.7
, Issue.1
, pp. 12-19
-
-
Kawai, T.1
Akira, S.2
-
82
-
-
56649092719
-
Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway
-
M. Langer, A. Malykhin, K. Maeda, K. Chakrabarty, K. S. Williamson, C. L. Feasley, C. M. West, J. P. Metcalf and K. M. Coggeshall: Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway. PLoS One, 3(11), e3706 (2008)
-
(2008)
PLoS One
, vol.3
, Issue.11
-
-
Langer, M.1
Malykhin, A.2
Maeda, K.3
Chakrabarty, K.4
Williamson, K.S.5
Feasley, C.L.6
West, C.M.7
Metcalf, J.P.8
Coggeshall, K.M.9
-
83
-
-
76549089581
-
Bacillus anthracis cell wall produces injurious inflammation but paradoxically decreases the lethality of anthrax lethal toxin in a rat model
-
X. Cui, J. Su, Y. Li, J. Shiloach, S. Solomon, J. B. Kaufman, H. Mani, Y. Fitz, J. Weng, L. Altaweel, V. Besch and P. Q. Eichacker: Bacillus anthracis cell wall produces injurious inflammation but paradoxically decreases the lethality of anthrax lethal toxin in a rat model. Intensive Care Med, 36(1), 148-56 (2010)
-
(2010)
Intensive Care Med
, vol.36
, Issue.1
, pp. 148-156
-
-
Cui, X.1
Su, J.2
Li, Y.3
Shiloach, J.4
Solomon, S.5
Kaufman, J.B.6
Mani, H.7
Fitz, Y.8
Weng, J.9
Altaweel, L.10
Besch, V.11
Eichacker, P.Q.12
-
84
-
-
19944433149
-
Late treatment with a protective antigen-directed monoclonal antibody improves hemodynamic function and survival in a lethal toxin-infused rat model of anthrax sepsis
-
X. Cui, Y. Li, M. Moayeri, G. H. Choi, G. M. Subramanian, X. Li, M. Haley, Y. Fitz, J. Feng, S. M. Banks, S. H. Leppla and P. Q. Eichacker: Late treatment with a protective antigen-directed monoclonal antibody improves hemodynamic function and survival in a lethal toxin-infused rat model of anthrax sepsis. J.Infect.Dis., 191(3), 422-434 (2005)
-
(2005)
J.Infect.Dis.
, vol.191
, Issue.3
, pp. 422-434
-
-
Cui, X.1
Li, Y.2
Moayeri, M.3
Choi, G.H.4
Subramanian, G.M.5
Li, X.6
Haley, M.7
Fitz, Y.8
Feng, J.9
Banks, S.M.10
Leppla, S.H.11
Eichacker, P.Q.12
-
85
-
-
33749244808
-
Prophylaxis and therapy of inhalational anthrax by a novel monoclonal antibody to protective antigen that mimics vaccine-induced immunity
-
L. Vitale, D. Blanset, I. Lowy, T. O'Neill, J. Goldstein, S. F. Little, G. P. Andrews, G. Dorough, R. K. Taylor and T. Keler: Prophylaxis and therapy of inhalational anthrax by a novel monoclonal antibody to protective antigen that mimics vaccine-induced immunity. Infect.Immun., 74(10), 5840-5847 (2006)
-
(2006)
Infect.Immun.
, vol.74
, Issue.10
, pp. 5840-5847
-
-
Vitale, L.1
Blanset, D.2
Lowy, I.3
O'Neill, T.4
Goldstein, J.5
Little, S.F.6
Andrews, G.P.7
Dorough, G.8
Taylor, R.K.9
Keler, T.10
-
86
-
-
84885939321
-
Evaluation of intravenous anthrax immune globulin for treatment of inhalation anthrax
-
N. Mytle, R. J. Hopkins, N. V. Malkevich, S. Basu, G. T. Meister, D. C. Sanford, J. E. Comer, K. E. Van Zandt, M. Al-Ibrahim, W. G. Kramer, C. Howard, N. Daczkowski, A. C. Chakrabarti, B. Ionin, G. S. Nabors and M. H. Skiadopoulos: Evaluation of intravenous anthrax immune globulin for treatment of inhalation anthrax. Antimicrob Agents Chemother, 57(11), 5684-92 (2013)
-
(2013)
Antimicrob Agents Chemother
, vol.57
, Issue.11
, pp. 5684-5692
-
-
Mytle, N.1
Hopkins, R.J.2
Malkevich, N.V.3
Basu, S.4
Meister, G.T.5
Sanford, D.C.6
Comer, J.E.7
Van Zandt, K.E.8
Al-Ibrahim, M.9
Kramer, W.G.10
Howard, C.11
Daczkowski, N.12
Chakrabarti, A.C.13
Ionin, B.14
Nabors, G.S.15
Skiadopoulos, M.H.16
-
87
-
-
20844461166
-
A phase 1 study of PAmAb, a fully human monoclonal antibody against Bacillus anthracis protective antigen, in healthy volunteers
-
G. M. Subramanian, P. W. Cronin, G. Poley, A. Weinstein, S. M. Stoughton, J. Zhong, Y. Ou, J. F. Zmuda, B. L. Osborn and W. W. Freimuth: A phase 1 study of PAmAb, a fully human monoclonal antibody against Bacillus anthracis protective antigen, in healthy volunteers. Clin Infect Dis, 41(1), 12-20 (2005)
-
(2005)
Clin Infect Dis
, vol.41
, Issue.1
, pp. 12-20
-
-
Subramanian, G.M.1
Cronin, P.W.2
Poley, G.3
Weinstein, A.4
Stoughton, S.M.5
Zhong, J.6
Ou, Y.7
Zmuda, J.F.8
Osborn, B.L.9
Freimuth, W.W.10
-
88
-
-
67650500264
-
Raxibacumab for the treatment of inhalational anthrax
-
T. S. Migone, G. M. Subramanian, J. Zhong, L. M. Healey, A. Corey, M. Devalaraja, L. Lo, S. Ullrich, J. Zimmerman, A. Chen, M. Lewis, G. Meister, K. Gillum, D. Sanford, J. Mott and S. D. Bolmer: Raxibacumab for the treatment of inhalational anthrax. N.Engl.J.Med., 361(2), 135-144 (2009)
-
(2009)
N.Engl.J.Med.
, vol.361
, Issue.2
, pp. 135-144
-
-
Migone, T.S.1
Subramanian, G.M.2
Zhong, J.3
Healey, L.M.4
Corey, A.5
Devalaraja, M.6
Lo, L.7
Ullrich, S.8
Zimmerman, J.9
Chen, A.10
Lewis, M.11
Meister, G.12
Gillum, K.13
Sanford, D.14
Mott, J.15
Bolmer, S.D.16
-
89
-
-
34249275349
-
Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model
-
K. Sherer, Y. Li, X. Cui, X. Li, M. Subramanian, M. W. Laird, M. Moayeri, S. H. Leppla, Y. Fitz, J. Su and P. Q. Eichacker: Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model. Crit Care Med, 35(6), 1560-7 (2007)
-
(2007)
Crit Care Med
, vol.35
, Issue.6
, pp. 1560-1567
-
-
Sherer, K.1
Li, Y.2
Cui, X.3
Li, X.4
Subramanian, M.5
Laird, M.W.6
Moayeri, M.7
Leppla, S.H.8
Fitz, Y.9
Su, J.10
Eichacker, P.Q.11
-
90
-
-
67650474225
-
Norepinephrine increases blood pressure but not survival with anthrax lethal toxin in rats
-
Y. Li, X. Cui, J. Su, M. Haley, H. Macarthur, K. Sherer, M. Moayeri, S. H. Leppla, Y. Fitz and P. Q. Eichacker: Norepinephrine increases blood pressure but not survival with anthrax lethal toxin in rats. Crit Care Med, 37(4), 1348-54 (2009)
-
(2009)
Crit Care Med
, vol.37
, Issue.4
, pp. 1348-1354
-
-
Li, Y.1
Cui, X.2
Su, J.3
Haley, M.4
Macarthur, H.5
Sherer, K.6
Moayeri, M.7
Leppla, S.H.8
Fitz, Y.9
Eichacker, P.Q.10
|