Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists

Journal of Experimental Medicine

Volumn 200, Issue 12, 2004, Pages 1647-1655

  Jin, Mo Park ^a   Ng, Vincent H ^b   Maeda, Shin ^a   Rest, Richard F ^b   Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Anthrax; Apoptosis; Infection; Innate immunity; Macrophage

Indexed keywords

ANTHROLYSIN O; BACTERIAL PROTEIN; CYTOLYSIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BACILLUS ANTHRACIS; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GRAM POSITIVE BACTERIUM; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; SUPERNATANT;

ANIMALS; ANTHRAX; ANTIGENS, BACTERIAL; APOPTOSIS; BACILLUS ANTHRACIS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BONE MARROW CELLS; MACROPHAGE ACTIVATION; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MEMBRANE GLYCOPROTEINS; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PORE FORMING CYTOTOXIC PROTEINS; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 11844262784     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041215     Document Type: Article

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