S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans

Free Radical Biology and Medicine

Volumn 73, Issue , 2014, Pages 127-135

  Cascella, Roberta ^a   Evangelisti, Elisa ^a   Zampagni, Mariagioia ^a   Becatti, Matteo ^a   D'Adamio, Giampiero ^b   Goti, Andrea ^b   Liguri, Gianfranco ^a   Fiorillo, Claudia ^a   Cecchi, Cristina ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

C. elegans; Daf 16 (FoxO); Free radicals; Glutathione; Longevity; Oxidative stress; Sir 2.1

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ESTER; GLUTATHIONE; GLUTATHIONE DERIVATIVE; HYDROGEN PEROXIDE; LINOLENIC ACID; S LINOLENOYL GLUTATHIONE; SIRTUIN 1; SIRTUIN 2; SIRTUIN 2.1; THIOESTER; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DAF-16 PROTEIN, C ELEGANS; SIR-2.1 PROTEIN, C ELEGANS; SIRTUIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ARTICLE; ASSAY; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; GENE OVEREXPRESSION; LIFE EXTENSION; LIFESPAN; LONGEVITY; MAMMAL; NONHUMAN; ORTHOLOGY; OXIDATIVE STRESS; PARALYSIS; PHENOTYPE; PRIORITY JOURNAL; RNA ANALYSIS; RNA INTERFERENCE; STRESS; UPREGULATION; WILD TYPE; WORM; AGING; ALZHEIMER DISEASE; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGICAL STRESS; TRANSCRIPTION INITIATION;

AGING; ALZHEIMER DISEASE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DIETARY SUPPLEMENTS; GLUTATHIONE; HYDROGEN PEROXIDE; LINOLENIC ACIDS; LONGEVITY; OXIDATIVE STRESS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIRTUINS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; VITAMIN E;

EID: 84902078725     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.05.004     Document Type: Article

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