Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide

Free Radical Biology and Medicine

Volumn 68, Issue , 2014, Pages 87-100

  Al Qenaei, Abdullah ^a   Yiakouvaki, Anthie ^a   Reelfs, Olivier ^a   Santambrogio, Paolo ^b   Levi, Sonia ^b,c   Hall, Nick D ^d   Tyrrell, Rex M ^a   Pourzand, Charareh ^a  

^a University of Bath   (United Kingdom)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^d Bath Institute for Rheumatic Diseases   (United Kingdom)

Author keywords

ATP; Desferrioxamine; Ferritin; Hydrogen peroxide; Labile iron; Lysosomes; Mitochondria; Mitochondrial ferritin; Necrosis; Oxidative stress; T cell

Indexed keywords

ANTIOXIDANT; FERRITIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; IRON; LABILE IRON POOL; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL LEVEL; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYSOSOME MEMBRANE; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; PRIORITY JOURNAL; T LYMPHOCYTE;

ATP; DESFERRIOXAMINE; FERRITIN; HYDROGEN PEROXIDE; LABILE IRON; LYSOSOMES; MITOCHONDRIA; MITOCHONDRIAL FERRITIN; NECROSIS; OXIDATIVE STRESS; T CELL;

ANTIOXIDANTS; FERRITINS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; HYDROGEN PEROXIDE; JURKAT CELLS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84890891957     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.12.006     Document Type: Article

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