Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1

Biogerontology

Volumn 11, Issue 2, 2010, Pages 183-195

  Heidler, Tanja ^a   Hartwig, Kai ^a   Daniel, Hannelore ^a   Wenzel, Uwe ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Caenorhabditis elegans; Glutathione; Hormesis; Reactive oxygen species; Small heat shock proteins; Stress response

Indexed keywords

GLUTATHIONE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 16.2; JUGLONE; PROTEIN SIR 2.1; REACTIVE OXYGEN METABOLITE; SILENT INFORMATION REGULATOR PROTEIN 2; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; CAENORHABDITIS ELEGANS; CELLULAR STRESS RESPONSE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG TOLERABILITY; ENZYME ACTIVITY; GENE DELETION; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TRANSLOCATION; LIFE EXTENSION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA INTERFERENCE; SURVIVAL RATE;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE DELETION; HEAT-SHOCK PROTEINS; KAPLAN-MEIERS ESTIMATE; LONGEVITY; MODELS, ANIMAL; NAPHTHOQUINONES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIRTUINS; TRANSCRIPTION FACTORS;

EID: 77950865186     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-009-9239-x     Document Type: Article

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