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Volumn 406, Issue 15, 2014, Pages 3553-3577

Screening and confirmation methods for GHB determination in biological fluids Forensic Toxicology

Author keywords

Gamma hydroxybutyric acid (GHB); Gas chromatography mass spectrometry (GC MS); Liquid chromatography tandem mass spectrometry (LC MS MS); Sample preparation

Indexed keywords

CAPILLARY ELECTROPHORESIS; CHEMICAL MODIFICATION; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

EID: 84901634669     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-7586-6     Document Type: Review
Times cited : (38)

References (128)
  • 2
    • 0037187357 scopus 로고    scopus 로고
    • Production of gamma-hydroxybutyric acid in postmortem liver increases with time after death
    • 1:CAS:528:DC%2BD38XhvVWnsb4%3D
    • Sakurada K, Kobayashi M, Iwase H, Yoshino M, Mukoyama H, Takatori T, Yoshida K (2002) Production of gamma-hydroxybutyric acid in postmortem liver increases with time after death. Toxicol Lett 129(3):207-217
    • (2002) Toxicol Lett , vol.129 , Issue.3 , pp. 207-217
    • Sakurada, K.1    Kobayashi, M.2    Iwase, H.3    Yoshino, M.4    Mukoyama, H.5    Takatori, T.6    Yoshida, K.7
  • 3
    • 33846592302 scopus 로고    scopus 로고
    • Clinical pharmacology of 1,4-butanediol and gamma-hydroxybutyrate after oral 1,4-butanediol administration to healthy volunteers
    • 1:CAS:528:DC%2BD2sXisFyrtLg%3D
    • Thai D, Dyer JE, Jacob P, Haller CA (2007) Clinical pharmacology of 1,4-butanediol and gamma-hydroxybutyrate after oral 1,4-butanediol administration to healthy volunteers. Clin Pharmacol Ther 81(2):178-184
    • (2007) Clin Pharmacol Ther , vol.81 , Issue.2 , pp. 178-184
    • Thai, D.1    Dyer, J.E.2    Jacob, P.3    Haller, C.A.4
  • 4
    • 0036591445 scopus 로고    scopus 로고
    • Club drugs: Methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate
    • 1:CAS:528:DC%2BD38XkvFSgsb8%3D
    • Smith KM, Larive LL, Romanelli F (2002) Club drugs: methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate. Am J Health Syst Pharm 59(11):1067-1076
    • (2002) Am J Health Syst Pharm , vol.59 , Issue.11 , pp. 1067-1076
    • Smith, K.M.1    Larive, L.L.2    Romanelli, F.3
  • 6
    • 0034837783 scopus 로고    scopus 로고
    • Gamma-hydroxybutyric acid: Patterns of use, effects and withdrawal
    • 1:STN:280:DC%2BD3MrjtlWqtA%3D%3D
    • Miotto K, Darakjian J, Basch J, Murray S, Zogg J, Rawson R (2001) Gamma-hydroxybutyric acid: Patterns of use, effects and withdrawal. Am J Addict 10(3):232-241
    • (2001) Am J Addict , vol.10 , Issue.3 , pp. 232-241
    • Miotto, K.1    Darakjian, J.2    Basch, J.3    Murray, S.4    Zogg, J.5    Rawson, R.6
  • 7
    • 67651093919 scopus 로고    scopus 로고
    • Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem): Differences in characteristics and misuse
    • 1:CAS:528:DC%2BD1MXosleiu7w%3D
    • Carter LP, Pardi D, Gorsline J, Griffiths RR (2009) Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem): differences in characteristics and misuse. Drug Alcohol Depend 104(1-2):1-10
    • (2009) Drug Alcohol Depend , vol.104 , Issue.1-2 , pp. 1-10
    • Carter, L.P.1    Pardi, D.2    Gorsline, J.3    Griffiths, R.R.4
  • 8
    • 0033822721 scopus 로고    scopus 로고
    • Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS
    • LeBeau MA, Montgomery MA, Miller ML, Burmeister SG (2000) Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS. J Anal Toxicol 24(6):421-428
    • (2000) J Anal Toxicol , vol.24 , Issue.6 , pp. 421-428
    • Ma, L.1    Montgomery, M.A.2    Miller, M.L.3    Burmeister, S.G.4
  • 9
    • 34249650188 scopus 로고    scopus 로고
    • Further evidence of in vitro production of gamma-hydroxybutyrate (GHB) in urine samples
    • 1:CAS:528:DC%2BD2sXmtVOlsb0%3D
    • LeBeau MA, Montgomery MA, Morris-Kukoski C, Schaff JE, Deakin A (2007) Further evidence of in vitro production of gamma-hydroxybutyrate (GHB) in urine samples. Forensic Sci Int 169(2-3):152-156
    • (2007) Forensic Sci Int , vol.169 , Issue.2-3 , pp. 152-156
    • Lebeau, M.A.1    Montgomery, M.A.2    Morris-Kukoski, C.3    Schaff, J.E.4    Deakin, A.5
  • 10
    • 0032983559 scopus 로고    scopus 로고
    • Prevalence of drugs used in cases of alleged sexual assault
    • 1:CAS:528:DyaK1MXjsVOgt78%3D
    • ElSohly MA, Salamone SJ (1999) Prevalence of drugs used in cases of alleged sexual assault. J Anal Tox 23(3):141-146
    • (1999) J Anal Tox , vol.23 , Issue.3 , pp. 141-146
    • Elsohly, M.A.1    Salamone, S.J.2
  • 11
    • 79951909577 scopus 로고    scopus 로고
    • Case series of 226 γ-hydroxybutyrate-associated deaths: Lethal toxicity and trauma
    • Zvosec DL, Smith SW, Porrata T, Strobl AQ, Dyer JE (2011) Case series of 226 γ-hydroxybutyrate-associated deaths: lethal toxicity and trauma. Am J Emerg Med 29(3):319-332
    • (2011) Am J Emerg Med , vol.29 , Issue.3 , pp. 319-332
    • Zvosec, D.L.1    Smith, S.W.2    Porrata, T.3    Strobl, A.Q.4    Dyer, J.E.5
  • 12
    • 0031745926 scopus 로고    scopus 로고
    • A tale of novel intoxication: Seven cases of gamma-hydroxybutyric acid overdose
    • 1:STN:280:DyaK1c3osleqtw%3D%3D
    • Li J, Stokes SA, Woeckener A (1998) A tale of novel intoxication: seven cases of gamma-hydroxybutyric acid overdose. Ann Emerg Med 31(6):723-728
    • (1998) Ann Emerg Med , vol.31 , Issue.6 , pp. 723-728
    • Li, J.1    Stokes, S.A.2    Woeckener, A.3
  • 15
    • 84901622514 scopus 로고    scopus 로고
    • Accessed 30 Oct 2013
    • EMCDDA website: http://www.emcdda.europa.eu/publications/edr/trends- developments/2013. Accessed 30 Oct 2013
    • EMCDDA Website
  • 16
    • 0038798803 scopus 로고    scopus 로고
    • Ultra-rapid procedure to test for gamma-hydroxybutyric acid in blood and urine by gas chromatography-mass spectrometry
    • 1:CAS:528:DC%2BD3sXkvVWjsLg%3D
    • Villain M, Cirimele V, Ludes B, Kintz P (2003) Ultra-rapid procedure to test for gamma-hydroxybutyric acid in blood and urine by gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 792(1):83-87
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.792 , Issue.1 , pp. 83-87
    • Villain, M.1    Cirimele, V.2    Ludes, B.3    Kintz, P.4
  • 17
    • 84857388905 scopus 로고    scopus 로고
    • Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose
    • Van Amsterdam JGC, Brunt TM, McMaster MTB, Niesink RJM (2012) Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose. Neurosci Biobehav Rev 36(4):1217-1227
    • (2012) Neurosci Biobehav Rev , vol.36 , Issue.4 , pp. 1217-1227
    • Van Amsterdam, J.G.C.1    Brunt, T.M.2    McMaster, M.T.B.3    Niesink, R.J.M.4
  • 18
    • 84863469235 scopus 로고    scopus 로고
    • The clinical toxicology of γ-hydroxybutyrate, γ-butyrolactone and 1,4-butanediol
    • 1:CAS:528:DC%2BC38XpsVKntbs%3D
    • Schep LJ, Knudsen K, Slaughter RJ, Vale JA, Mégarbane B (2012) The clinical toxicology of γ-hydroxybutyrate, γ-butyrolactone and 1,4-butanediol. Clin Toxicol 50(6):458-470
    • (2012) Clin Toxicol , vol.50 , Issue.6 , pp. 458-470
    • Schep, L.J.1    Knudsen, K.2    Slaughter, R.J.3    Vale, J.A.4    Mégarbane, B.5
  • 19
    • 70350102176 scopus 로고    scopus 로고
    • Epidemiology of recreational drug toxicity in a nightclub environment
    • Wood DM, Nicolaou M, Dargan PI (2009) Epidemiology of recreational drug toxicity in a nightclub environment. Subst Use Misuse 44:1495-1502
    • (2009) Subst Use Misuse , vol.44 , pp. 1495-1502
    • Wood, D.M.1    Nicolaou, M.2    Dargan, P.I.3
  • 21
    • 0035138115 scopus 로고    scopus 로고
    • Gamma-hydroxybutyrate withdrawal syndrome
    • 1:STN:280:DC%2BD3M7kvFOntw%3D%3D
    • Dyer JE, Roth B, Hyma BA (2001) Gamma-hydroxybutyrate withdrawal syndrome. Ann Emerg Med 37(2):147-153
    • (2001) Ann Emerg Med , vol.37 , Issue.2 , pp. 147-153
    • Dyer, J.E.1    Roth, B.2    Hyma, B.A.3
  • 22
    • 47249117171 scopus 로고    scopus 로고
    • Withdrawal from gamma-hydroxybutyrate, 1,4-butanediol and gamma-butyrolactone: A case report and systematic review
    • Wojtowicz JM, Yarema MC, Wax PM (2008) Withdrawal from gamma-hydroxybutyrate, 1,4-butanediol and gamma-butyrolactone: a case report and systematic review. CJEM 10(1):69-74
    • (2008) CJEM , vol.10 , Issue.1 , pp. 69-74
    • Wojtowicz, J.M.1    Yarema, M.C.2    Wax, P.M.3
  • 23
    • 0018088956 scopus 로고
    • Identification of endogenous gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig and rhesus monkey brain
    • 1:CAS:528:DyaE1cXmtFamtrw%3D
    • Doherty JD, Hattox SE, Snead OC, Roth RH (1978) Identification of endogenous gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig and rhesus monkey brain. J Pharmacol Exp Ther 207(1):130-139
    • (1978) J Pharmacol Exp Ther , vol.207 , Issue.1 , pp. 130-139
    • Doherty, J.D.1    Hattox, S.E.2    Snead, O.C.3    Roth, R.H.4
  • 24
    • 0018176540 scopus 로고
    • Improved pharmacological activity via pro-drug modification: Comparative pharmacokinetics of sodium gamma-hydroxybutyrate and gamma-butyrolactone
    • 1:CAS:528:DyaE1MXhs1SmsA%3D%3D
    • Lettieri J, Fung HL (1978) Improved pharmacological activity via pro-drug modification: comparative pharmacokinetics of sodium gamma-hydroxybutyrate and gamma-butyrolactone. Res Commun Chem Pathol Pharmacol 22(1):107-118
    • (1978) Res Commun Chem Pathol Pharmacol , vol.22 , Issue.1 , pp. 107-118
    • Lettieri, J.1    Fung, H.L.2
  • 25
    • 0017070495 scopus 로고
    • Rapid determination of 4-hydroxybutyric acid and 2-propylpentanoate in human plasma by means of gas-liquid chromatography
    • 1:CAS:528:DyaE28XksFKnt7w%3D
    • Vree TB, Van der Kleijn E, Knop HJ (1976) Rapid determination of 4-hydroxybutyric acid and 2-propylpentanoate in human plasma by means of gas-liquid chromatography. J Chrom 121:150-152
    • (1976) J Chrom , vol.121 , pp. 150-152
    • Vree, T.B.1    Van Der Kleijn, E.2    Knop, H.J.3
  • 26
    • 84907123026 scopus 로고
    • Circadian rhythm in plasma concentrations of gamma-hydroxybutyric acid in alcoholics
    • 1:STN:280:DyaL387ovFShtA%3D%3D
    • Hoes MJ, Vree TB, Guelen PJ (1981) Circadian rhythm in plasma concentrations of gamma-hydroxybutyric acid in alcoholics. Int J Addict 16(6):1071-1075
    • (1981) Int J Addict , vol.16 , Issue.6 , pp. 1071-1075
    • Hoes, M.J.1    Vree, T.B.2    Guelen, P.J.3
  • 28
    • 10044267443 scopus 로고    scopus 로고
    • Position of chromatographic techniques in screening for detection of drugs or poisons in clinical and forensic toxicology and/or doping control
    • 1:CAS:528:DC%2BD2cXhtVGqtbnK
    • Maurer HH (2004) Position of chromatographic techniques in screening for detection of drugs or poisons in clinical and forensic toxicology and/or doping control. Clin Chem Lab Med 42(11):1310-1324
    • (2004) Clin Chem Lab Med , vol.42 , Issue.11 , pp. 1310-1324
    • Maurer, H.H.1
  • 29
    • 0034529812 scopus 로고    scopus 로고
    • Determination of γ-hydroxybutyric acid (GHB) in plasma and urine by headspace solid-phase microextraction and gas chromatography/positive ion chemical ionization mass spectrometry
    • 1:CAS:528:DC%2BD3MXhsFWjsA%3D%3D
    • Frison G, Tedeschi L, Maietti S, Ferrara SD (2000) Determination of γ-hydroxybutyric acid (GHB) in plasma and urine by headspace solid-phase microextraction and gas chromatography/positive ion chemical ionization mass spectrometry. Rapid Com Mass Spectr 14(24):2401-2407
    • (2000) Rapid Com Mass Spectr , vol.14 , Issue.24 , pp. 2401-2407
    • Frison, G.1    Tedeschi, L.2    Maietti, S.3    Ferrara, S.D.4
  • 30
    • 57749102002 scopus 로고    scopus 로고
    • Intoxications due to ingestion of gamma-butyrolactone: Organ distribution of gamma-hydroxybutyric acid and gamma-butyrolactone
    • Lenz D, Rothschild MA, Kröner L (2008) Intoxications due to ingestion of gamma-butyrolactone: organ distribution of gamma-hydroxybutyric acid and gamma-butyrolactone. Ther Drug Monit 30(6):755-761
    • (2008) Ther Drug Monit , vol.30 , Issue.6 , pp. 755-761
    • Lenz, D.1    Rothschild, M.A.2    Kröner, L.3
  • 31
    • 12344330442 scopus 로고    scopus 로고
    • Analysis of GHB and 4-methyl-GHB in postmortem matrices after long-term storage
    • 1:CAS:528:DC%2BD2MXktF2qsg%3D%3D
    • Marinetti LJ, Isenschmid DS, Hepler BR, Kanluen S (2005) Analysis of GHB and 4-methyl-GHB in postmortem matrices after long-term storage. J Anal Toxicol 29(1):41-47
    • (2005) J Anal Toxicol , vol.29 , Issue.1 , pp. 41-47
    • Marinetti, L.J.1    Isenschmid, D.S.2    Hepler, B.R.3    Kanluen, S.4
  • 32
    • 18244400250 scopus 로고    scopus 로고
    • Endogenous level and in vitro production of GHB in blood from healthy humans, and the interpretation of GHB levels detected in antemortem blood samples
    • 1:CAS:528:DC%2BD2MXktFOhur0%3D
    • Shima N, Miki A, Kamata T, Katagi M, Tsuchihashi H (2005) Endogenous level and in vitro production of GHB in blood from healthy humans, and the interpretation of GHB levels detected in antemortem blood samples. J Health Sci 51(2):147-154
    • (2005) J Health Sci , vol.51 , Issue.2 , pp. 147-154
    • Shima, N.1    Miki, A.2    Kamata, T.3    Katagi, M.4    Tsuchihashi, H.5
  • 33
    • 33748304405 scopus 로고    scopus 로고
    • GC-MS-MS determination of gamma-hydroxybutyrate in blood and urine
    • 1:CAS:528:DC%2BD28Xnt1aitb0%3D
    • Paul R, Tsanaclis L, Kingston R, Berry A, Guwy A (2006) GC-MS-MS determination of gamma-hydroxybutyrate in blood and urine. J Anal Toxicol 30(6):375-379
    • (2006) J Anal Toxicol , vol.30 , Issue.6 , pp. 375-379
    • Paul, R.1    Tsanaclis, L.2    Kingston, R.3    Berry, A.4    Guwy, A.5
  • 34
    • 8644251470 scopus 로고    scopus 로고
    • Simultaneous analysis of gamma-hydroxybutyric acid and its precursors in urine using liquid chromatography-tandem mass spectrometry
    • 1:CAS:528:DC%2BD2cXpsFels7o%3D
    • Wood M, Laloup M, Samyn N, Morris MR, de Bruijn EA, Maes RA, Young MS, Maes V, De Boeck G (2004) Simultaneous analysis of gamma-hydroxybutyric acid and its precursors in urine using liquid chromatography-tandem mass spectrometry. J Chromatogr A 1056(1-2):83-90
    • (2004) J Chromatogr A , vol.1056 , Issue.1-2 , pp. 83-90
    • Wood, M.1    Laloup, M.2    Samyn, N.3    Morris, M.R.4    De Bruijn, E.A.5    Maes, R.A.6    Young, M.S.7    Maes, V.8    De Boeck, G.9
  • 35
    • 79954630845 scopus 로고    scopus 로고
    • A validated GC-MS procedure for fast, simple, and cost-effective quantification of glycols and GHB in human plasma and their identification in urine and plasma developed for emergency toxicology
    • 1:CAS:528:DC%2BC3MXitFKjtb8%3D
    • Meyer MR, Weber AA, Maurer HH (2011) A validated GC-MS procedure for fast, simple, and cost-effective quantification of glycols and GHB in human plasma and their identification in urine and plasma developed for emergency toxicology. Anal Bioanal Chem 400(2):411-414
    • (2011) Anal Bioanal Chem , vol.400 , Issue.2 , pp. 411-414
    • Meyer, M.R.1    Weber, A.A.2    Maurer, H.H.3
  • 36
    • 10044243409 scopus 로고    scopus 로고
    • Analysis of gamma-hydroxybutyric acid, DL-lactic acid, glycolic acid, ethylene glycol and other glycols in body fluids by a direct injection gas chromatography-mass spectrometry assay for wide use
    • Van hee P, Neels H, De Doncker M, Vrydags N, Schatteman K, Uyttenbroeck W, Hamers N, Himpe D, Lambert WE (2004) Analysis of gamma-hydroxybutyric acid, DL-lactic acid, glycolic acid, ethylene glycol and other glycols in body fluids by a direct injection gas chromatography-mass spectrometry assay for wide use. Clin Chem Lab Med 42(11):1341-1345
    • (2004) Clin Chem Lab Med , vol.42 , Issue.11 , pp. 1341-1345
    • Van Hee, P.1    Neels, H.2    De Doncker, M.3    Vrydags, N.4    Schatteman, K.5    Uyttenbroeck, W.6    Hamers, N.7    Himpe, D.8    Lambert, W.E.9
  • 37
    • 0034958275 scopus 로고    scopus 로고
    • Improved procedure for the analysis of gamma-hydroxybutyrate and ethylene glycol in whole blood
    • 1:CAS:528:DC%2BD3MXlsFalsrs%3D
    • Pan YM, Gill GN, Tilson CS, Wall WH, McCurdy HH (2001) Improved procedure for the analysis of gamma-hydroxybutyrate and ethylene glycol in whole blood. J Anal Toxicol 25(5):328-332
    • (2001) J Anal Toxicol , vol.25 , Issue.5 , pp. 328-332
    • Pan, Y.M.1    Gill, G.N.2    Tilson, C.S.3    Wall, W.H.4    McCurdy, H.H.5
  • 38
    • 34547693200 scopus 로고    scopus 로고
    • A validated SPME-GC-MS method for simultaneous quantification of club drugs in human urine
    • 1:CAS:528:DC%2BD2sXovFGnu7s%3D
    • Brown SD, Rhodes DJ, Pritchard BJ (2007) A validated SPME-GC-MS method for simultaneous quantification of club drugs in human urine. Forensic Sci Int 171(2-3):142-150
    • (2007) Forensic Sci Int , vol.171 , Issue.2-3 , pp. 142-150
    • Brown, S.D.1    Rhodes, D.J.2    Pritchard, B.J.3
  • 39
    • 84876028295 scopus 로고    scopus 로고
    • Uptake of gamma-valerolactone-detection of gamma-hydroxyvaleric acid in human urine samples
    • 1:CAS:528:DC%2BC3sXlsVCktL4%3D
    • Andresen-Streichert H, Jungen H, Gehl A, Müller A, Iwersen-Bergmann S (2013) Uptake of gamma-valerolactone-detection of gamma-hydroxyvaleric acid in human urine samples. J Anal Toxicol 37(4):250-254
    • (2013) J Anal Toxicol , vol.37 , Issue.4 , pp. 250-254
    • Andresen-Streichert, H.1    Jungen, H.2    Gehl, A.3    Müller, A.4    Iwersen-Bergmann, S.5
  • 41
    • 84878695123 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with "in-vial" derivatization and headspace-trap gas chromatography-mass spectrometry
    • Ingels ASME, Neels H, Lambert WE, Stove CP (2013) Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with "in-vial" derivatization and headspace-trap gas chromatography-mass spectrometry. J Chromatogr A 1296:84-92
    • (2013) J Chromatogr A , vol.1296 , pp. 84-92
    • Asme, I.1    Neels, H.2    Lambert, W.E.3    Stove, C.P.4
  • 42
    • 0037023189 scopus 로고    scopus 로고
    • Capillary gas chromatographic determination of 1,4-butanediol and gamma-hydroxybutyrate in human plasma and urine
    • 1:CAS:528:DC%2BD38XhvVeqtLg%3D
    • Blanchet B, Morand K, Hulin A, Astier A (2002) Capillary gas chromatographic determination of 1,4-butanediol and gamma-hydroxybutyrate in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci 769(2):221-226
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.769 , Issue.2 , pp. 221-226
    • Blanchet, B.1    Morand, K.2    Hulin, A.3    Astier, A.4
  • 43
    • 0032857258 scopus 로고    scopus 로고
    • Analysis of gamma-hydroxybutyrate (GHB) in urine by gas chromatography-mass spectrometry
    • 1:CAS:528:DyaK1MXlvVWisrg%3D
    • McCusker RR, Paget-Wilkes H, Chronister CW, Goldberger BA (1999) Analysis of gamma-hydroxybutyrate (GHB) in urine by gas chromatography-mass spectrometry. J Anal Toxicol 23(5):301-305
    • (1999) J Anal Toxicol , vol.23 , Issue.5 , pp. 301-305
    • McCusker, R.R.1    Paget-Wilkes, H.2    Chronister, C.W.3    Goldberger, B.A.4
  • 44
    • 78049347658 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct "on spot" derivatization
    • 1:CAS:528:DC%2BC3cXhtFCltrrK
    • Ingels AS, Lambert WE, Stove CP (2010) Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct "on spot" derivatization. Anal Bioanal Chem 398(5):2173-2182
    • (2010) Anal Bioanal Chem , vol.398 , Issue.5 , pp. 2173-2182
    • Ingels, A.S.1    Lambert, W.E.2    Stove, C.P.3
  • 45
    • 1642580601 scopus 로고    scopus 로고
    • Further evidence for the presence of GHB in postmortem biological fluid: Implications for the interpretation of findings
    • 1:CAS:528:DC%2BD2cXjtVGkuw%3D%3D
    • Elliott SP (2004) Further evidence for the presence of GHB in postmortem biological fluid: implications for the interpretation of findings. J Anal Toxicol 28(1):20-26
    • (2004) J Anal Toxicol , vol.28 , Issue.1 , pp. 20-26
    • Elliott, S.P.1
  • 46
    • 0035877204 scopus 로고    scopus 로고
    • Effect of storage temperature on endogenous GHB levels in urine
    • 1:CAS:528:DC%2BD3MXjslSmurk%3D
    • LeBeau MA, Miller ML, Levine B (2001) Effect of storage temperature on endogenous GHB levels in urine. Forensic Sci Int 119(2):161-167
    • (2001) Forensic Sci Int , vol.119 , Issue.2 , pp. 161-167
    • Lebeau, M.A.1    Miller, M.L.2    Levine, B.3
  • 47
    • 0036707903 scopus 로고    scopus 로고
    • Intra- and interindividual variations in urinary concentrations of endogenous gamma-hydroxybutyrate
    • 1:CAS:528:DC%2BD38XmsF2nu7o%3D
    • LeBeau MA, Christenson RH, Levine B, Darwin WD, Huestis MA (2002) Intra- and interindividual variations in urinary concentrations of endogenous gamma-hydroxybutyrate. J Anal Toxicol 26(6):340-346
    • (2002) J Anal Toxicol , vol.26 , Issue.6 , pp. 340-346
    • Lebeau, M.A.1    Christenson, R.H.2    Levine, B.3    Darwin, W.D.4    Huestis, M.A.5
  • 48
    • 0037190163 scopus 로고    scopus 로고
    • Determination of endogenous gamma-hydroxybutyric acid (GHB) levels in antemortem urine and blood
    • 1:CAS:528:DC%2BD38Xmtlertrw%3D
    • Elian AA (2002) Determination of endogenous gamma-hydroxybutyric acid (GHB) levels in antemortem urine and blood. Forensic Sci Int 128(3):120-122
    • (2002) Forensic Sci Int , vol.128 , Issue.3 , pp. 120-122
    • Elian, A.A.1
  • 49
    • 0038706464 scopus 로고    scopus 로고
    • Gamma hydroxybutyric acid (GHB) concentrations in humans and factors affecting endogenous production
    • 1:CAS:528:DC%2BD3sXjs1aisbs%3D
    • Elliott SP (2003) Gamma hydroxybutyric acid (GHB) concentrations in humans and factors affecting endogenous production. Forensic Sci Int 133(1-2):9-16
    • (2003) Forensic Sci Int , vol.133 , Issue.1-2 , pp. 9-16
    • Elliott, S.P.1
  • 50
    • 77953915671 scopus 로고    scopus 로고
    • Gamma-hydroxybutyrate in urine and serum: Additional data supporting current cut-off recommendations
    • 1:CAS:528:DC%2BC3cXotVagtr8%3D
    • Andresen H, Sprys N, Schmoldt A, Mueller A, Iwersen-Bergmann S (2010) Gamma-hydroxybutyrate in urine and serum: Additional data supporting current cut-off recommendations. Forensic Sci Int 200(1-3):93-99
    • (2010) Forensic Sci Int , vol.200 , Issue.1-3 , pp. 93-99
    • Andresen, H.1    Sprys, N.2    Schmoldt, A.3    Mueller, A.4    Iwersen-Bergmann, S.5
  • 51
    • 79954604138 scopus 로고    scopus 로고
    • Endogenous γ-hydroxybutyric acid concentrations in saliva determined by gas chromatography-mass spectrometry
    • De Paoli G, Walker KM, Pounder DJ (2011) Endogenous γ- hydroxybutyric acid concentrations in saliva determined by gas chromatography-mass spectrometry. J Anal Toxicol 35(3):148-152
    • (2011) J Anal Toxicol , vol.35 , Issue.3 , pp. 148-152
    • De Paoli, G.1    Walker, K.M.2    Pounder, D.J.3
  • 52
    • 3042835336 scopus 로고    scopus 로고
    • GHB in postmortem toxicology. Discrimination between endogenous production from exposure using multiple specimens
    • 1:CAS:528:DC%2BD2cXlsVSktbg%3D
    • Kintz P, Villain M, Cirimele V, Ludes B (2004) GHB in postmortem toxicology. Discrimination between endogenous production from exposure using multiple specimens. Forensic Sci Int 143(2-3):177-181
    • (2004) Forensic Sci Int , vol.143 , Issue.2-3 , pp. 177-181
    • Kintz, P.1    Villain, M.2    Cirimele, V.3    Ludes, B.4
  • 53
    • 0034237236 scopus 로고    scopus 로고
    • Coma and respiratory depression following the ingestion of ghb and its precursors: Three cases
    • 1:STN:280:DC%2BD3czpslSrtg%3D%3D
    • Ingels M, Rangan C, Bellezzo J, Clark RF (2000) Coma and respiratory depression following the ingestion of ghb and its precursors: Three cases. J Emerg Med 19(1):47-50
    • (2000) J Emerg Med , vol.19 , Issue.1 , pp. 47-50
    • Ingels, M.1    Rangan, C.2    Bellezzo, J.3    Clark, R.F.4
  • 54
    • 0038706412 scopus 로고    scopus 로고
    • Forensic cases involving the use of GHB in the Netherlands
    • 1:CAS:528:DC%2BD3sXjs1aisbY%3D
    • Bosman IJ, Lusthof KJ (2003) Forensic cases involving the use of GHB in the Netherlands. Forensic Sci Int 133(1-2):17-21
    • (2003) Forensic Sci Int , vol.133 , Issue.1-2 , pp. 17-21
    • Bosman, I.J.1    Lusthof, K.J.2
  • 56
    • 3342878967 scopus 로고    scopus 로고
    • Nonfatal instances of intoxication with gamma-hydroxybutyrate in the United Kingdom
    • 1:CAS:528:DC%2BD2cXls1Kjtbc%3D
    • Elliott SP (2004) Nonfatal instances of intoxication with gamma-hydroxybutyrate in the United Kingdom. Ther Drug Monit 26(4):432-440
    • (2004) Ther Drug Monit , vol.26 , Issue.4 , pp. 432-440
    • Elliott, S.P.1
  • 57
    • 16544373543 scopus 로고    scopus 로고
    • γ-Hydroxybutyrate. Bridging the clinical-analytical gap
    • 1:CAS:528:DC%2BD2MXitFyluw%3D%3D
    • Morris-Kukoski CL (2004) γ-Hydroxybutyrate. Bridging the clinical-analytical gap. Toxicol Rev 23(1):33-43
    • (2004) Toxicol Rev , vol.23 , Issue.1 , pp. 33-43
    • Morris-Kukoski, C.L.1
  • 58
    • 84901592055 scopus 로고    scopus 로고
    • TIAFT Accessed 9 Sept 2013
    • TIAFT website; http://www.tiaft.org/. Accessed 9 Sept 2013
  • 59
    • 0036863582 scopus 로고    scopus 로고
    • In vitro production of gamma-hydroxybutyrate in antemortem urine samples
    • 1:CAS:528:DC%2BD38XpsVOrsb0%3D
    • Kerrigan S (2002) In vitro production of gamma-hydroxybutyrate in antemortem urine samples. J Anal Toxicol 26(8):571-574
    • (2002) J Anal Toxicol , vol.26 , Issue.8 , pp. 571-574
    • Kerrigan, S.1
  • 60
    • 1042275873 scopus 로고    scopus 로고
    • The possible influence of micro-organisms and putrefaction in the production of GHB in post-mortem biological fluid
    • 1:CAS:528:DC%2BD2cXhtV2mtbc%3D
    • Elliott S, Lowe P, Symonds A (2004) The possible influence of micro-organisms and putrefaction in the production of GHB in post-mortem biological fluid. Forensic Sci Int 139(2-3):183-190
    • (2004) Forensic Sci Int , vol.139 , Issue.2-3 , pp. 183-190
    • Elliott, S.1    Lowe, P.2    Symonds, A.3
  • 61
    • 76849111358 scopus 로고    scopus 로고
    • Forensic toxicology findings in deaths involving gamma-hydroxybutyrate
    • Kugelberg FC, Holmgren A, Eklund A, Jones AW (2010) Forensic toxicology findings in deaths involving gamma-hydroxybutyrate. Int J Legal Med 124(1):1-6
    • (2010) Int J Legal Med , vol.124 , Issue.1 , pp. 1-6
    • Kugelberg, F.C.1    Holmgren, A.2    Eklund, A.3    Jones, A.W.4
  • 62
    • 8444220448 scopus 로고    scopus 로고
    • A reference range for endogenous gamma-hydroxybutyrate in urine by gas chromatography-mass spectrometry
    • 1:CAS:528:DC%2BD2cXptlyns74%3D
    • Crookes CE, Faulds MC, Forrest AR, Galloway JH (2004) A reference range for endogenous gamma-hydroxybutyrate in urine by gas chromatography-mass spectrometry. J Anal Toxicol 28(8):644-649
    • (2004) J Anal Toxicol , vol.28 , Issue.8 , pp. 644-649
    • Crookes, C.E.1    Faulds, M.C.2    Forrest, A.R.3    Galloway, J.H.4
  • 63
    • 84876710145 scopus 로고    scopus 로고
    • Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home: An exploratory study
    • 1:CAS:528:DC%2BC3sXhvVSmtbbJ
    • Ingels AS, Hertegonne KB, Lambert WE, Stove CP (2013) Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home: an exploratory study. CNS Drugs 27(3):233-237
    • (2013) CNS Drugs , vol.27 , Issue.3 , pp. 233-237
    • Ingels, A.S.1    Hertegonne, K.B.2    Lambert, W.E.3    Stove, C.P.4
  • 64
    • 29144472296 scopus 로고    scopus 로고
    • Detection of exogenous GHB in blood by gas chromatography-combustion- isotope ratio mass spectrometry: Implications in postmortem toxicology
    • 1:CAS:528:DC%2BD2MXht1CqsLjP
    • Saudan C, Augsburger M, Kintz P, Saugy M, Mangin P (2005) Detection of exogenous GHB in blood by gas chromatography-combustion-isotope ratio mass spectrometry: implications in postmortem toxicology. J Anal Toxicol 29(8):777-781
    • (2005) J Anal Toxicol , vol.29 , Issue.8 , pp. 777-781
    • Saudan, C.1    Augsburger, M.2    Kintz, P.3    Saugy, M.4    Mangin, P.5
  • 66
    • 33847126261 scopus 로고    scopus 로고
    • Disposition of gamma-hydroxybutyric acid in conventional and nonconventional biologic fluids after single drug administration: Issues in methodology and drug monitoring
    • 1:CAS:528:DC%2BD2sXhslCmtbs%3D
    • Abanades S, Farré M, Segura M, Pichini S, Pastor A, Pacifici R, Pellegrini M, de la Torre R (2007) Disposition of gamma-hydroxybutyric acid in conventional and nonconventional biologic fluids after single drug administration: issues in methodology and drug monitoring. Ther Drug Monit 29(1):64-70
    • (2007) Ther Drug Monit. , vol.29 , Issue.1 , pp. 64-70
    • Abanades, S.1    Farré, M.2    Segura, M.3    Pichini, S.4    Pastor, A.5    Pacifici, R.6    Pellegrini, M.7    De La Torre, R.8
  • 67
    • 80054866763 scopus 로고    scopus 로고
    • Dried blood spot punches for confirmation of suspected gamma-hydroxybutyric acid intoxications: Validation of an optimized GC-MS procedure
    • 1:CAS:528:DC%2BC3MXhtleru7rJ
    • Ingels AS, De Paepe P, Anseeuw K, Van Sassenbroeck DK, Neels H, Lambert WE, Stove CP (2011) Dried blood spot punches for confirmation of suspected gamma-hydroxybutyric acid intoxications: validation of an optimized GC-MS procedure. Bioanalysis 3:2271-2281
    • (2011) Bioanalysis , vol.3 , pp. 2271-2281
    • Ingels, A.S.1    De Paepe, P.2    Anseeuw, K.3    Van Sassenbroeck, D.K.4    Neels, H.5    Lambert, W.E.6    Stove, C.P.7
  • 68
    • 84891372549 scopus 로고    scopus 로고
    • Quantitation of gamma-hydroxybutyric acid in dried blood spots: Feasibility assessment for newborn screening of succinic semialdehyde dehydrogenase (SSADH) deficiency
    • 1:CAS:528:DC%2BC3sXoslWru7Y%3D
    • Forni S, Pearl PL, Gibson KM, Yu Y, Sweetman L (2013) Quantitation of gamma-hydroxybutyric acid in dried blood spots: feasibility assessment for newborn screening of succinic semialdehyde dehydrogenase (SSADH) deficiency. Mol Genet Metab 109(3):255-259
    • (2013) Mol Genet Metab , vol.109 , Issue.3 , pp. 255-259
    • Forni, S.1    Pearl, P.L.2    Gibson, K.M.3    Yu, Y.4    Sweetman, L.5
  • 69
    • 43549111847 scopus 로고    scopus 로고
    • A rapid GC-MS determination of gamma-hydroxybutyrate in saliva
    • De Paoli G, Bell S (2008) A rapid GC-MS determination of gamma-hydroxybutyrate in saliva. J Anal Toxicol 32(4):298-302
    • (2008) J Anal Toxicol , vol.32 , Issue.4 , pp. 298-302
    • De Paoli, G.1    Bell, S.2
  • 70
    • 0034771196 scopus 로고    scopus 로고
    • Window of Detection of γ-Hydroxybutyrate in Blood and Saliva
    • 1:CAS:528:DC%2BD3MXnvF2jurc%3D
    • Kintz P, Goullé JP, Cirimele V, Ludes B (2001) Window of Detection of γ-Hydroxybutyrate in Blood and Saliva. Clin Chem 47(11):2033-2034
    • (2001) Clin Chem , vol.47 , Issue.11 , pp. 2033-2034
    • Kintz, P.1    Goullé, J.P.2    Cirimele, V.3    Ludes, B.4
  • 71
    • 0037225806 scopus 로고    scopus 로고
    • Testing for GHB in hair by GC/MS/MS after a single exposure. Application to document sexual assault
    • 1:CAS:528:DC%2BD3sXhtVSntL8%3D
    • Kintz P, Cirimele V, Jamey C, Ludes B (2003) Testing for GHB in hair by GC/MS/MS after a single exposure. Application to document sexual assault. J Forensic Sci 48(1):195-200
    • (2003) J Forensic Sci , vol.48 , Issue.1 , pp. 195-200
    • Kintz, P.1    Cirimele, V.2    Jamey, C.3    Ludes, B.4
  • 72
    • 0344629152 scopus 로고    scopus 로고
    • Determination of endogenous levels of GHB in human hair. Are there possibilities for the identification of GHB administration through hair analysis in cases of drug-facilitated sexual assault?
    • Goullé JP, Chèze M, Pépin G (2003) Determination of endogenous levels of GHB in human hair. Are there possibilities for the identification of GHB administration through hair analysis in cases of drug-facilitated sexual assault? J Anal Toxicol 27(8):574-580
    • (2003) J Anal Toxicol , vol.27 , Issue.8 , pp. 574-580
    • Goullé, J.P.1    Chèze, M.2    Pépin, G.3
  • 73
    • 84901619743 scopus 로고    scopus 로고
    • Interpretation of GHB concentrations in hair
    • 1:CAS:528:DC%2BC3MXksVGktro%3D
    • Cirimele V, Baumgartner M, Vallet E, Duez M (2010) Interpretation of GHB concentrations in hair. Ann Toxicol Analyt 22(4):161-164
    • (2010) Ann Toxicol Analyt , vol.22 , Issue.4 , pp. 161-164
    • Cirimele, V.1    Baumgartner, M.2    Vallet, E.3    Duez, M.4
  • 74
    • 84882969147 scopus 로고    scopus 로고
    • Identification of a new metabolite of GHB: Gamma-hydroxybutyric acid glucuronide
    • 1:CAS:528:DC%2BC3sXnsVOhurc%3D
    • Petersen IN, Tortzen C, Kristensen JL, Pedersen DS, Breindahl T (2013) Identification of a new metabolite of GHB: gamma-hydroxybutyric acid glucuronide. J Anal Toxicol 37(5):291-297
    • (2013) J Anal Toxicol , vol.37 , Issue.5 , pp. 291-297
    • Petersen, I.N.1    Tortzen, C.2    Kristensen, J.L.3    Pedersen, D.S.4    Breindahl, T.5
  • 75
    • 33748935167 scopus 로고    scopus 로고
    • Determination of the illicit drug gamma-hydroxybutyrate (GHB) in human saliva and beverages by 1H NMR analysis
    • 1:CAS:528:DC%2BD28XpslGgs7g%3D
    • Grootveld M, Algeo D, Silwood CJ, Blackburn JC, Clark AD (2006) Determination of the illicit drug gamma-hydroxybutyrate (GHB) in human saliva and beverages by 1H NMR analysis. Biofactors 27(1-4):121-136
    • (2006) Biofactors , vol.27 , Issue.1-4 , pp. 121-136
    • Grootveld, M.1    Algeo, D.2    Silwood, C.J.3    Blackburn, J.C.4    Clark, A.D.5
  • 76
    • 84865321351 scopus 로고    scopus 로고
    • LC-MS vs. GC-MS, online extraction systems, advantages of technology for drug screening assays
    • 1:CAS:528:DC%2BC3sXitFagsLk%3D
    • Marquet P (2012) LC-MS vs. GC-MS, online extraction systems, advantages of technology for drug screening assays. Methods Mol Biol 902:15-27
    • (2012) Methods Mol Biol , vol.902 , pp. 15-27
    • Marquet, P.1
  • 77
    • 84901592056 scopus 로고    scopus 로고
    • Bühlmann laboratories Accessed 26 Aug 2013
    • Bühlmann laboratories, http://www.buhlmannlabs.ch/core/clinical- chemistry/ghb-kinetic/. Accessed 26 Aug 2013
  • 78
    • 0033044084 scopus 로고    scopus 로고
    • Rapid screening test for gamma-hydroxybutyric acid (GHB, Fantasy) in urine
    • 1:STN:280:DyaK1M3ptFOkug%3D%3D
    • Badcock NR, Zotti R (1999) Rapid screening test for gamma-hydroxybutyric acid (GHB, Fantasy) in urine. Ther Drug Monit 21(3):376
    • (1999) Ther Drug Monit , vol.21 , Issue.3 , pp. 376
    • Badcock, N.R.1    Zotti, R.2
  • 79
    • 0037129056 scopus 로고    scopus 로고
    • Rapid colorimetric screening test for gamma-hydroxybutyric acid (liquid X) in human urine
    • 1:CAS:528:DC%2BD38XkslGqtL4%3D
    • Alston WC 2nd, Ng K (2002) Rapid colorimetric screening test for gamma-hydroxybutyric acid (liquid X) in human urine. Forensic Sci Int 126(2):114-117
    • (2002) Forensic Sci Int , vol.126 , Issue.2 , pp. 114-117
    • Alston II, W.C.1    Ng, K.2
  • 80
    • 1542317063 scopus 로고    scopus 로고
    • Reliable, sensitive, rapid and quantitative enzyme-based assay for gamma-hydroxybutyric acid (GHB)
    • 1:CAS:528:DC%2BD2cXislygtLY%3D
    • Bravo DT, Harris DO, Parsons SM (2004) Reliable, sensitive, rapid and quantitative enzyme-based assay for gamma-hydroxybutyric acid (GHB). J Forensic Sci 49(2):379-387
    • (2004) J Forensic Sci , vol.49 , Issue.2 , pp. 379-387
    • Bravo, D.T.1    Harris, D.O.2    Parsons, S.M.3
  • 81
    • 84901622513 scopus 로고    scopus 로고
    • Drugcheck Accessed 26 Aug 2013
    • Drugcheck, http://www.drugcheck.com/dc-ghb.html. Accessed 26 Aug 2013
  • 82
    • 78650959629 scopus 로고    scopus 로고
    • Development and characterization of an enzymatic method for the rapid determination of gamma hydroxybutyric acid
    • 1:CAS:528:DC%2BC3cXhsF2ksrfK
    • Sciotti MA, Hasan L, Scholer A, Jermann TM, Weber JM, Gygax D (2010) Development and characterization of an enzymatic method for the rapid determination of gamma hydroxybutyric acid. Chimia 64(11):793-798
    • (2010) Chimia , vol.64 , Issue.11 , pp. 793-798
    • Sciotti, M.A.1    Hasan, L.2    Scholer, A.3    Jermann, T.M.4    Weber, J.M.5    Gygax, D.6
  • 84
    • 84871050086 scopus 로고    scopus 로고
    • Enzymatic assay for GHB determination in forensic matrices
    • 1:CAS:528:DC%2BC38Xht1KjtrbI
    • Grenier V, Huppé G, Lamarche M, Mireault P (2012) Enzymatic assay for GHB determination in forensic matrices. J Anal Toxicol 36(7):523-528
    • (2012) J Anal Toxicol , vol.36 , Issue.7 , pp. 523-528
    • Grenier, V.1    Huppé, G.2    Lamarche, M.3    Mireault, P.4
  • 85
    • 11844257041 scopus 로고    scopus 로고
    • 1H NMR analysis of GHB and GBL: Further findings on the interconversion and a preliminary report on the analysis of GHB in serum and urine
    • Del Signore AG, McGregor M, Cho BP (2005) 1H NMR analysis of GHB and GBL: further findings on the interconversion and a preliminary report on the analysis of GHB in serum and urine. J Forensic Sci 50(1):81-86
    • (2005) J Forensic Sci , vol.50 , Issue.1 , pp. 81-86
    • Del Signore, A.G.1    McGregor, M.2    Cho, B.P.3
  • 86
    • 33750160080 scopus 로고    scopus 로고
    • Applications of ion mobility spectrometry (IMS) to the analysis of gamma-hydroxybutyrate and gamma-hydroxyvalerate in toxicological matrices
    • 1:CAS:528:DC%2BD28XhtVOlsbzM
    • Mercer J, Shakleya D, Bell S (2006) Applications of ion mobility spectrometry (IMS) to the analysis of gamma-hydroxybutyrate and gamma-hydroxyvalerate in toxicological matrices. J Anal Toxicol 30(8):539-544
    • (2006) J Anal Toxicol , vol.30 , Issue.8 , pp. 539-544
    • Mercer, J.1    Shakleya, D.2    Bell, S.3
  • 87
    • 4644263437 scopus 로고    scopus 로고
    • Rapid and direct analysis of gamma-hydroxybutyric acid in urine by capillary electrophoresis-electrospray ionization ion-trap mass spectrometry
    • 1:CAS:528:DC%2BD2cXotV2hsr8%3D
    • Gottardo R, Bortolotti F, Trettene M, De Paoli G, Tagliaro F (2004) Rapid and direct analysis of gamma-hydroxybutyric acid in urine by capillary electrophoresis-electrospray ionization ion-trap mass spectrometry. J Chromatogr A 1051(1-2):207-211
    • (2004) J Chromatogr A , vol.1051 , Issue.1-2 , pp. 207-211
    • Gottardo, R.1    Bortolotti, F.2    Trettene, M.3    De Paoli, G.4    Tagliaro, F.5
  • 88
    • 0037459173 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyric acid in human urine by capillary electrophoresis with indirect UV detection and confirmation with electrospray ionization ion-trap mass spectrometry
    • 1:CAS:528:DC%2BD3sXhvFKjsLY%3D
    • Baldacci A, Theurillat R, Caslavska J, Pardubská H, Brenneisen R, Thormann W (2003) Determination of gamma-hydroxybutyric acid in human urine by capillary electrophoresis with indirect UV detection and confirmation with electrospray ionization ion-trap mass spectrometry. J Chromatogr A 990(1-2):99-110
    • (2003) J Chromatogr A , vol.990 , Issue.1-2 , pp. 99-110
    • Baldacci, A.1    Theurillat, R.2    Caslavska, J.3    Pardubská, H.4    Brenneisen, R.5    Thormann, W.6
  • 89
    • 40849113303 scopus 로고    scopus 로고
    • A new method for the HPLC determination of gamma-hydroxybutyric acid (GHB) following derivatization with a coumarin analogue and fluorescence detection: Application in the analysis of biological fluids
    • 1:CAS:528:DC%2BD1cXjtl2rurw%3D
    • Zacharis CK, Raikos N, Giouvalakis N, Tsoukali-Papadopoulou H, Theodoridis GA (2008) A new method for the HPLC determination of gamma-hydroxybutyric acid (GHB) following derivatization with a coumarin analogue and fluorescence detection: application in the analysis of biological fluids. Talanta 75(2):356-361
    • (2008) Talanta , vol.75 , Issue.2 , pp. 356-361
    • Zacharis, C.K.1    Raikos, N.2    Giouvalakis, N.3    Tsoukali-Papadopoulou, H.4    Theodoridis, G.A.5
  • 90
    • 0348047460 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyric acid in biological fluids by using capillary electrophoresis with indirect detection
    • 1:CAS:528:DC%2BD3sXhtVSjtbrN
    • Bortolotti F, De Paoli G, Gottardo R, Trattene M, Tagliaro F (2004) Determination of gamma-hydroxybutyric acid in biological fluids by using capillary electrophoresis with indirect detection. J Chromatogr B Analyt Technol Biomed Life Sci 800(1-2):239-244
    • (2004) J Chromatogr B Analyt Technol Biomed Life Sci , vol.800 , Issue.1-2 , pp. 239-244
    • Bortolotti, F.1    De Paoli, G.2    Gottardo, R.3    Trattene, M.4    Tagliaro, F.5
  • 92
    • 0037173959 scopus 로고    scopus 로고
    • Rapid and sensitive detection of urinary 4-hydroxybutyric acid and its related compounds by gas chromatography-mass spectrometry in a patient with succinic semialdehyde dehydrogenase deficiency
    • 1:CAS:528:DC%2BD38XmvFGitbg%3D
    • Shinka T, Inoue Y, Ohse M, Ito A, Ohfu M, Hirose S, Kuhara T (2002) Rapid and sensitive detection of urinary 4-hydroxybutyric acid and its related compounds by gas chromatography-mass spectrometry in a patient with succinic semialdehyde dehydrogenase deficiency. J Chromatogr B Analyt Technol Biomed Life Sci 776(1):57-63
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.776 , Issue.1 , pp. 57-63
    • Shinka, T.1    Inoue, Y.2    Ohse, M.3    Ito, A.4    Ohfu, M.5    Hirose, S.6    Kuhara, T.7
  • 94
    • 33847126226 scopus 로고    scopus 로고
    • Use of urine organic acids method for the analysis of gamma-hydroxybutric acid (GHB): Importance of urease in eliminating urea interference
    • 1:CAS:528:DC%2BD2sXjtlems7c%3D
    • Garg U, Scott D, Kiscoan M, Knoblauch J, Frazee CC 3rd, Wasserman G (2007) Use of urine organic acids method for the analysis of gamma-hydroxybutric acid (GHB): importance of urease in eliminating urea interference. Clin Toxicol 45(2):194-196
    • (2007) Clin Toxicol , vol.45 , Issue.2 , pp. 194-196
    • Garg, U.1    Scott, D.2    Kiscoan, M.3    Knoblauch, J.4    Frazee III, C.C.5    Wasserman, G.6
  • 95
    • 77957029803 scopus 로고    scopus 로고
    • Headspace in-tube extraction gas chromatography-mass spectrometry for the analysis of hydroxylic methyl-derivatized and volatile organic compounds in blood and urine
    • 1:CAS:528:DC%2BC3cXksVOitrk%3D
    • Rasanen I, Viinamäki J, Vuori E, Ojanperä I (2010) Headspace in-tube extraction gas chromatography-mass spectrometry for the analysis of hydroxylic methyl-derivatized and volatile organic compounds in blood and urine. J Anal Toxicol 34(3):113-121
    • (2010) J Anal Toxicol , vol.34 , Issue.3 , pp. 113-121
    • Rasanen, I.1    Viinamäki, J.2    Vuori, E.3    Ojanperä, I.4
  • 96
    • 77952291436 scopus 로고    scopus 로고
    • Simultaneous screening for and determination of 128 date-rape drugs in urine by gas chromatography-electron ionization-mass spectrometry
    • 1:CAS:528:DC%2BC3cXltF2msr4%3D
    • Adamowicz P, Kała M (2010) Simultaneous screening for and determination of 128 date-rape drugs in urine by gas chromatography-electron ionization-mass spectrometry. Forensic Sci Int 198(1-3):39-45
    • (2010) Forensic Sci Int , vol.198 , Issue.1-3 , pp. 39-45
    • Adamowicz, P.1    Kała, M.2
  • 97
    • 84882773842 scopus 로고    scopus 로고
    • Quantitation of gamma-hydroxybutyric acid in dried blood spots in newborns screening
    • 1:CAS:528:DC%2BC3sXhtFCgsbnE
    • Stove CP, Ingels AS, Lambert WE (2013) Quantitation of gamma-hydroxybutyric acid in dried blood spots in newborns screening. Mol Genet Metab 110(1-2):195
    • (2013) Mol Genet Metab , vol.110 , Issue.1-2 , pp. 195
    • Stove, C.P.1    Ingels, A.S.2    Lambert, W.E.3
  • 98
    • 84882863587 scopus 로고    scopus 로고
    • Response to Stove and colleagues concerning newborn screening of succinic semialdehyde dehydrogenase (SSADH) deficiency in dried blood spots
    • 1:CAS:528:DC%2BC3sXhtFWku7fP
    • Forni S, Pearl PL, Gibson KM, Yu Y, Sweetman L (2013) Response to Stove and colleagues concerning newborn screening of succinic semialdehyde dehydrogenase (SSADH) deficiency in dried blood spots. Mol Genet Metab 110(1-2):196
    • (2013) Mol Genet Metab , vol.110 , Issue.1-2 , pp. 196
    • Forni, S.1    Pearl, P.L.2    Gibson, K.M.3    Yu, Y.4    Sweetman, L.5
  • 99
    • 84856628887 scopus 로고    scopus 로고
    • Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS
    • Dahl SR, Olsen KM, Strand DH (2012) Determination of γ- hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS. J Chromatogr B Analyt Technol Biomed Life Sci 885-886:37-42
    • (2012) J Chromatogr B Analyt Technol Biomed Life Sci , vol.885-886 , pp. 37-42
    • Dahl, S.R.1    Olsen, K.M.2    Strand, D.H.3
  • 100
    • 34547380878 scopus 로고    scopus 로고
    • Bioanalytical procedures for determination of drugs of abuse in blood
    • 1:CAS:528:DC%2BD2sXnsVeqtrg%3D
    • Kraemer T, Paul LD (2007) Bioanalytical procedures for determination of drugs of abuse in blood. Anal Bioanal Chem 388(7):1415-1435
    • (2007) Anal Bioanal Chem , vol.388 , Issue.7 , pp. 1415-1435
    • Kraemer, T.1    Paul, L.D.2
  • 101
    • 0037849901 scopus 로고    scopus 로고
    • Before the injection-modern methods of sample preparation for separation techniques
    • 1:CAS:528:DC%2BD3sXktFGgsrw%3D
    • Smith RM (2003) Before the injection-modern methods of sample preparation for separation techniques. J Chromatogr A 1000(1-2):3-27
    • (2003) J Chromatogr A. , vol.1000 , Issue.1-2 , pp. 3-27
    • Smith, R.M.1
  • 102
    • 79954524398 scopus 로고    scopus 로고
    • Simultaneous determination of γ-Hydroxybutyrate (GHB) and its analogues (GBL, 1.4-BD, GVL) in whole blood and urine by liquid chromatography coupled to tandem mass spectrometry
    • 1:CAS:528:DC%2BC3MXht1yksbg%3D
    • Johansen SS, Windberg CN (2011) Simultaneous determination of γ-Hydroxybutyrate (GHB) and its analogues (GBL, 1.4-BD, GVL) in whole blood and urine by liquid chromatography coupled to tandem mass spectrometry. J Anal Toxicol 35(1):8-14
    • (2011) J Anal Toxicol , vol.35 , Issue.1 , pp. 8-14
    • Johansen, S.S.1    Windberg, C.N.2
  • 103
    • 55949109118 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyric acid in clinical samples using capillary electrophoresis with contactless conductivity detection
    • 1:CAS:528:DC%2BD1cXhsVajt7bJ
    • Gong XY, Kubán P, Scholer A, Hauser PC (2008) Determination of gamma-hydroxybutyric acid in clinical samples using capillary electrophoresis with contactless conductivity detection. J Chromatogr A 1213(1):100-104
    • (2008) J Chromatogr A , vol.1213 , Issue.1 , pp. 100-104
    • Gong, X.Y.1    Kubán, P.2    Scholer, A.3    Hauser, P.C.4
  • 104
    • 0034987409 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyrate in water and human urine by solid phase microextraction-gas chromatography/quadrupole ion trap spectrometry
    • 1:CAS:528:DC%2BD3MXktFKisbg%3D
    • Blair S, Song M, Hall B, Brodbelt J (2001) Determination of gamma-hydroxybutyrate in water and human urine by solid phase microextraction-gas chromatography/quadrupole ion trap spectrometry. J Forensic Sci 46(3):688-693
    • (2001) J Forensic Sci , vol.46 , Issue.3 , pp. 688-693
    • Blair, S.1    Song, M.2    Hall, B.3    Brodbelt, J.4
  • 105
    • 34447631151 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyrate (GHB) and its precursors in blood and urine samples: A salting-out approach
    • Kankaanpää A, Liukkonen R, Ariniemi K (2007) Determination of gamma-hydroxybutyrate (GHB) and its precursors in blood and urine samples: a salting-out approach. Forensic Sci Int 170(2-3):133-138
    • (2007) Forensic Sci Int , vol.170 , Issue.2-3 , pp. 133-138
    • Kankaanpää, A.1    Liukkonen, R.2    Ariniemi, K.3
  • 106
    • 82555181614 scopus 로고    scopus 로고
    • Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS
    • 1:CAS:528:DC%2BC3MXhsFertLrO
    • Elie MP, Baron MG, Birkett JW (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst 137(1):255-262
    • (2012) Analyst , vol.137 , Issue.1 , pp. 255-262
    • Elie, M.P.1    Baron, M.G.2    Birkett, J.W.3
  • 107
    • 82955195422 scopus 로고    scopus 로고
    • Anion exchange SPE and liquid chromatography-tandem mass spectrometry in GHB analysis
    • 1:CAS:528:DC%2BC3MXhsFSktrjO
    • Elian AA, Hackett J (2011) Anion exchange SPE and liquid chromatography-tandem mass spectrometry in GHB analysis. J Chromatogr B Analyt Technol Biomed Life Sci 879(31):3752-3758
    • (2011) J Chromatogr B Analyt Technol Biomed Life Sci , vol.879 , Issue.31 , pp. 3752-3758
    • Elian, A.A.1    Hackett, J.2
  • 109
    • 84865637029 scopus 로고    scopus 로고
    • A hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry method for the simultaneous determination of γ- hydroxybutyrate and its precursors in forensic whole blood
    • Sørensen LK, Hasselstrøm JB (2012) A hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry method for the simultaneous determination of γ-hydroxybutyrate and its precursors in forensic whole blood. Forensic Sci Int 222(1-3):352-359
    • (2012) Forensic Sci Int , vol.222 , Issue.1-3 , pp. 352-359
    • Sørensen, L.K.1    Hasselstrøm, J.B.2
  • 110
    • 0037420211 scopus 로고    scopus 로고
    • Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry
    • 1:CAS:528:DC%2BD3sXmtVaksbc%3D
    • Polson C, Sarkar P, Incledon B, Raguvaran V, Grant R (2003) Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 785(2):263-275
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.785 , Issue.2 , pp. 263-275
    • Polson, C.1    Sarkar, P.2    Incledon, B.3    Raguvaran, V.4    Grant, R.5
  • 111
    • 0141459551 scopus 로고    scopus 로고
    • Stability of plasma gamma-hydroxybutyrate determined by gas chromatography-positive ion chemical ionization-mass spectrometry
    • 1:CAS:528:DC%2BD3sXos1Glu70%3D
    • Chen M, Andrenyak DM, Moody DE, Foltz RL (2003) Stability of plasma gamma-hydroxybutyrate determined by gas chromatography-positive ion chemical ionization-mass spectrometry. J Anal Toxicol 27(7):445-458
    • (2003) J Anal Toxicol , vol.27 , Issue.7 , pp. 445-458
    • Chen, M.1    Andrenyak, D.M.2    Moody, D.E.3    Foltz, R.L.4
  • 112
    • 0030770985 scopus 로고    scopus 로고
    • A sudden awakening from a near coma after combined intake of gamma-hydroxybutyric acid (GHB) and ethanol
    • 1:CAS:528:DyaK2sXns1ymtLY%3D
    • Louagie HK, Verstraete AG, De Soete CJ, Baetens DG, Calle PA (1997) A sudden awakening from a near coma after combined intake of gamma-hydroxybutyric acid (GHB) and ethanol. J Toxicol Clin Toxicol 35(6):591-594
    • (1997) J Toxicol Clin Toxicol , vol.35 , Issue.6 , pp. 591-594
    • Louagie, H.K.1    Verstraete, A.G.2    De Soete, C.J.3    Baetens, D.G.4    Calle, P.A.5
  • 113
    • 35348862353 scopus 로고    scopus 로고
    • Prevalence of gamma-hydroxybutyrate (GHB) in serum samples of amphetamine, metamphetamine and ecstasy impaired drivers
    • 1:CAS:528:DC%2BD2sXhtF2rtrvE
    • Dresen S, Kempf J, Weinmann W (2007) Prevalence of gamma-hydroxybutyrate (GHB) in serum samples of amphetamine, metamphetamine and ecstasy impaired drivers. Forensic Sci Int 173(2-3):112-116
    • (2007) Forensic Sci Int , vol.173 , Issue.2-3 , pp. 112-116
    • Dresen, S.1    Kempf, J.2    Weinmann, W.3
  • 114
    • 84864337844 scopus 로고    scopus 로고
    • Estimation of gamma-hydroxybutyric acid (GHB) co-consumption in serum samples of drivers positive for amphetamine or ecstasy
    • 1:CAS:528:DC%2BC38XmsVGrurc%3D
    • Lott S, Musshoff F, Madea B (2012) Estimation of gamma-hydroxybutyric acid (GHB) co-consumption in serum samples of drivers positive for amphetamine or ecstasy. Forensic Sci Int 221(1-3):98-101
    • (2012) Forensic Sci Int , vol.221 , pp. 98-101
    • Lott, S.1    Musshoff, F.2    Madea, B.3
  • 115
    • 0034790965 scopus 로고    scopus 로고
    • Application of a convenient extraction procedure to analyze gamma-hydroxybutyric acid in fatalities involving gamma-hydroxybutyric acid, gamma-butyrolactone, and 1,4-butanediol
    • 1:CAS:528:DC%2BD3MXnsVCgsro%3D
    • Duer WC, Byers KL, Martin JV (2001) Application of a convenient extraction procedure to analyze gamma-hydroxybutyric acid in fatalities involving gamma-hydroxybutyric acid, gamma-butyrolactone, and 1,4-butanediol. J Anal Toxicol 25(7):576-582
    • (2001) J Anal Toxicol , vol.25 , Issue.7 , pp. 576-582
    • Duer, W.C.1    Byers, K.L.2    Martin, J.V.3
  • 116
    • 37349037839 scopus 로고    scopus 로고
    • Gamma-hydroxybutyrate concentrations in the blood of impaired drivers, users of illicit drugs, and medical examiner cases
    • 1:CAS:528:DC%2BD2sXhtlCls7rF
    • Jones AW, Holmgren A, Kugelberg FC (2007) Gamma-hydroxybutyrate concentrations in the blood of impaired drivers, users of illicit drugs, and medical examiner cases. J Anal Toxicol 31(9):566-572
    • (2007) J Anal Toxicol , vol.31 , Issue.9 , pp. 566-572
    • Jones, A.W.1    Holmgren, A.2    Kugelberg, F.C.3
  • 117
    • 84880829476 scopus 로고    scopus 로고
    • Adduct supported analysis of γ-hydroxybutyrate in human serum with LC-MS-MS
    • 1:CAS:528:DC%2BC3sXosVGltb8%3D
    • Dziadosz M, Weller JP, Klintschar M, Teske J (2013) Adduct supported analysis of γ-hydroxybutyrate in human serum with LC-MS-MS. Anal Bioanal Chem 405(20):6595-6597
    • (2013) Anal Bioanal Chem , vol.405 , Issue.20 , pp. 6595-6597
    • Dziadosz, M.1    Weller, J.P.2    Klintschar, M.3    Teske, J.4
  • 118
    • 33646852104 scopus 로고    scopus 로고
    • Recent trends in analytical procedures in forensic toxicology
    • Van Bocxlaer JF (2005) Recent trends in analytical procedures in forensic toxicology. Ther Drug Monit 27(6):752-755
    • (2005) Ther Drug Monit , vol.27 , Issue.6 , pp. 752-755
    • Van Bocxlaer, J.F.1
  • 119
    • 0037465137 scopus 로고    scopus 로고
    • Validation of a simple gas chromatographic-mass spectrometric method for the determination of gamma-butyrolactone in human plasma
    • 1:CAS:528:DC%2BD3sXmtVyru78%3D
    • Fukui Y, Matsusima E, Muramoto K, Nagai N, Ohama K, Yamashita K (2003) Validation of a simple gas chromatographic-mass spectrometric method for the determination of gamma-butyrolactone in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 785(1):73-80
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.785 , Issue.1 , pp. 73-80
    • Fukui, Y.1    Matsusima, E.2    Muramoto, K.3    Nagai, N.4    Ohama, K.5    Yamashita, K.6
  • 120
    • 63449106117 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyric acid in serum and urine by headspace solid-phase dynamic extraction combined with gas chromatography- positive chemical ionization mass spectrometry
    • 1:CAS:528:DC%2BD1MXkt1SlsL4%3D
    • Lenz D, Kröner L, Rothschild MA (2009) Determination of gamma-hydroxybutyric acid in serum and urine by headspace solid-phase dynamic extraction combined with gas chromatography-positive chemical ionization mass spectrometry. J Chromatogr A 1216(18):4090-4096
    • (2009) J Chromatogr A , vol.1216 , Issue.18 , pp. 4090-4096
    • Lenz, D.1    Kröner, L.2    Rothschild, M.A.3
  • 122
    • 0033983897 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyrate (GHB) in biological specimens by gas chromatography-mass spectrometry
    • 1:CAS:528:DC%2BD3cXntFGisQ%3D%3D
    • Couper FJ, Logan BK (2000) Determination of gamma-hydroxybutyrate (GHB) in biological specimens by gas chromatography-mass spectrometry. J Anal Toxicol 24(1):1-7
    • (2000) J Anal Toxicol , vol.24 , Issue.1 , pp. 1-7
    • Couper, F.J.1    Logan, B.K.2
  • 124
    • 0034630419 scopus 로고    scopus 로고
    • A novel method for GHB detection in urine and its application in drug-facilitated sexual assaults
    • 1:CAS:528:DC%2BD3cXhvVOrsbg%3D
    • Elian AA (2000) A novel method for GHB detection in urine and its application in drug-facilitated sexual assaults. Forensic Sci Int 109(3):183-187
    • (2000) Forensic Sci Int , vol.109 , Issue.3 , pp. 183-187
    • Elian, A.A.1
  • 125
    • 23944512395 scopus 로고    scopus 로고
    • Distribution of GHB in tissues and fluids following a fatal overdose
    • 1:CAS:528:DC%2BD2MXmvVGhsbg%3D
    • Mazarr-Proo S, Kerrigan S (2005) Distribution of GHB in tissues and fluids following a fatal overdose. J Anal Toxicol 29(5):398-400
    • (2005) J Anal Toxicol , vol.29 , Issue.5 , pp. 398-400
    • Mazarr-Proo, S.1    Kerrigan, S.2
  • 126
    • 0035888360 scopus 로고    scopus 로고
    • GC-MS determination of gamma-hydroxybutyric acid (GHB) in blood
    • 1:CAS:528:DC%2BD3MXnt1Wiu70%3D
    • Elian AA (2001) GC-MS determination of gamma-hydroxybutyric acid (GHB) in blood. Forensic Sci Int 122(1):43-47
    • (2001) Forensic Sci Int , vol.122 , Issue.1 , pp. 43-47
    • Elian, A.A.1
  • 127
    • 34247332999 scopus 로고    scopus 로고
    • Determination of GHB in urine and serum by LC/MS using a simple one-step derivative
    • 1:CAS:528:DC%2BD2sXkslCgtLk%3D
    • Kaufmann E, Alt A (2007) Determination of GHB in urine and serum by LC/MS using a simple one-step derivative. Forensic Sci Int 168(2-3):133-137
    • (2007) Forensic Sci Int , vol.168 , Issue.2-3 , pp. 133-137
    • Kaufmann, E.1    Alt, A.2
  • 128
    • 2942615356 scopus 로고    scopus 로고
    • Liquid chromatographic-mass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma
    • 1:CAS:528:DC%2BD2cXltVKisLY%3D
    • Fung HL, Haas E, Raybon J, Xu J, Fung SM (2004) Liquid chromatographic-mass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma. J Chromatogr B Analyt Technol Biomed Life Sci 807(2):287-291
    • (2004) J Chromatogr B Analyt Technol Biomed Life Sci , vol.807 , Issue.2 , pp. 287-291
    • Fung, H.L.1    Haas, E.2    Raybon, J.3    Xu, J.4    Fung, S.M.5


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