Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 785, Issue 2, 2003, Pages 263-275

  Polson, Cara ^a,b   Sarkar, Pratibha ^a   Incledon, Bev ^a   Raguvaran, Vanaja ^a   Grant, Russell ^a  

^a Lilly Laboratory for B R   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

Proteins

Indexed keywords

ORGANIC ACIDS; PLASMA DIAGNOSTICS; PROTEINS; SODIUM CHLORIDE; SPECTROPHOTOMETRY; ZINC COMPOUNDS;

PROTEIN PRECIPITATION TECHNIQUES;

ORGANIC SOLVENTS;

ACETONITRILE; METHANOL; PLASMA PROTEIN; SOLVENT; TRICHLOROACETIC ACID; WATER; ZINC SULFATE;

ARTICLE; ASSAY; INFUSION; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA; PRECIPITATION; PRIORITY JOURNAL; PROTEIN BINDING; SPECIES COMPARISON;

ANIMALS; BLOOD PROTEINS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DOGS; HUMANS; MASS SPECTROMETRY; MICE; RATS; REFERENCE STANDARDS; SERUM ALBUMIN; SOLVENTS; SPECIES SPECIFICITY;

EID: 0037420211     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(02)00914-5     Document Type: Article

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