Stability of plasma gamma-hydroxybutyrate determined by gas chromatography-positive ion chemical ionization-mass spectrometry

Journal of Analytical Toxicology

Volumn 27, Issue 7, 2003, Pages 445-448

  Chen, Meng ^a   Andrenyak, David M ^a   Moody, David E ^a   Foltz, Rodger L ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBUTYRIC ACID; ACETONITRILE; AMMONIA; N,O BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE; TRIFLUOROACETAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; DRUG STORAGE; GAS CHROMATOGRAPHY; HUMAN; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; ROOM TEMPERATURE; STORAGE TEMPERATURE; TEMPERATURE SENSITIVITY; THAWING;

EID: 0141459551     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/27.7.445     Document Type: Article

References (23)

1. R.H. Roth and N.J. Giarman. Conversion in vivo of γ-hydroxybutyric acid in mammalian brain. Biochem. Pharmacol. 18: 247-250 (1969).
2. 14C]-butyrate by rat brain: relationship to the Krebs cycle and metabolic compartmentation of amino acids. J. Neurochem. 30: 1305-1309 (1978).
3. K.M. Gibson, G.F. Hoffmann, A.K. Hodson, T. Bottiglieri, and C. Jakobs. 4-Hydroxybutyric acid and the clinical phenotype of succinic semialdehyde dehydrogenase deficiency, an inborn error of GABA metabolism. Neuropediatrics. 29: 14-22 (1998).
4. T. O'Connell, L. Kaye, and J.J. Ploday. Gamma-hydroxybutyrate (GHB): a newer drug of abuse. Am. Fam. Physician. 62: 2478-2483 (2000).
5. Multistate outbreak of poisoning associated with illicit use of gamma hydroxy butyrate. Morb. Mortal. Wkly. Rep. 39: 861-863 (1990).
6. A.B. Schneir, B.T. Ly, and R.F. Clark. A case of withdrawal from the GHB precursors gamma-butryolactone and 1,4-butanediol. J. Emerg. Med. 21: 31-33 (2001).
7. Gamma hydroxy butyrate use-New York and Texas, 1995-1996. MMWR Morb. Mortal. Wkly. Rep. 46: 281-283 (1997).
8. M.A. ElSohly and S.J. Salamone. Prevalence of drugs used in cases of alleged sexual assault. J. Anal. Toxicol. 23: 141-146 (1999).
9. M.A. LeBeau, M.A. Montgomery, M.L. Miller, and S.G. Burmeister. Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS. J. Anal. Toxicol. 24: 421-428 (2000).
10. F.J. Couper and B.K. Logan. Determination of γ-hydroxybutyrate (GHB) in biological specimens by gas chromatography-mass spectrometry. J. Anal. Toxicol. 24: 1-7 (2000).
11. T.B. Vree and E.V.D. Kleijn. Rapid determination of 4-hydroxybutyric acid (gamma OH) and 2-propylpentanoate (Depakine) in human plasma by means of gas-liquid chromatography. J. Chromatogr. 121: 150-152 (1976).
12. R.R. McCusker, H. Paget-Wilkes, C.W. Chronister, and B.A. Goldberger. Analysis of gamma-hydroxybutyrate (GHB) in urine by gas chromatography-mass spectrometry. J. Anal. Toxicol. 23: 301-305 (1999).
13. C.A. de Vriendt, D.K. van Sassenbroeck, M.T. Rosseel, E.J. van de Velde, A.G. Verstraete, Y. Vander Heyden, and F.M. Belpaire. Development and validation of a high performance liquid chromatographic method for the determination of γ-hydroxybutyric acid in rat plasma. J. Chromatogr. B 752: 85-90 (2001).
14. M.Z. Mesmer and R.D. Satzer. Determination of gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by HPLC/UV-VIS spectrometry and HPLC/thermospray mass spectrometry. J. Forensic Sci. 43: 489-492 (1998).
15. A.G. Verstraete, E.V.D. Velde, P.D. Paepe, and M.T. Rosseel. Determination of gamma-hydroxybutyrate (GHB) in serum or plasma with GC/MS. X. Zagadnien Nauk Sadowych 62: 195-201 (2000).
16. K.S. Kalasinsky, M.M. Dixon, G.A. Schmunk, and S.J. Kish. Blood, brain, and hair GHB concentrations following fatal ingestion. J. Forensic Sci. 46: 728-730 (2001).
17. G. Frison, L. Tedeschi, and S.D. Ferrara. Determination gamma-hydroxybutyric acid (GHB) in plasma and urine by headspace solid-phase microextraction and gas chromatography/positive ion chemical ionization mass spectrometry. Rapid Commun. Mass Spectrom 14: 2401-2407 (2000).
18. A.A. Elian. A novel method for GHB detection in urine and its application in drug-facilitated sexual assaults. Forensic Sci. Int. 109: 183-187 (2000).
19. J.D. Doherty, S.E. Hattox, O.C. Snead, and R.H. Roth. Identification of endogenous γ-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pigs and rhesus monkey brain. J. Pharmacol. Exp. Ther. 207: 130-139 (1978).
20. O.C. Snead, G.B. Brown, and R.B. Morawetz. Concentration of gamma-hydroxybutyric acid in ventricular and lumbar cerebrospinal fluid. N. Engl. J. Med. 304: 93-95 (1981).
21. F.J. Couper and B.K. Logan. Driving under the influence of GHB. J. Anal. Toxicol. 25: 365 (2001).
22. J.M. Pearson and M.L. Blackburn. Analysis of gamma-hydroxybutyrate (GHB) in whole blood and urine by GC-MS. J. Anal. Toxicol. 25: 366 (2001).
23. M.A. LeBeau. Elevated GHB in citrate-buffered blood. J. Anal. Toxicol. 24: 383-384 (2000).