Clinical pharmacology of 1,4-butanediol and gamma-hydroxybutyrate after oral 1,4-butanediol administration to healthy volunteers

Clinical Pharmacology and Therapeutics

Volumn 81, Issue 2, 2007, Pages 178-184

  Thai, D ^a   Dyer, J E ^b   Jacob, P ^c   Haller, C A ^c  

^a AMGEN INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BUTANEDIOL; 4 HYDROXYBUTYRIC ACID; ALCOHOL DEHYDROGENASE;

ADULT; ALERTNESS; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIZZINESS; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; FEMALE; GAS CHROMATOGRAPHY; HAPLOTYPE; HUMAN; MALE; MASS SPECTROMETRY; MONITORING; MOOD; NORMAL HUMAN; OXYGEN SATURATION; PRIORITY JOURNAL; PULSE OXIMETRY; SYSTOLIC BLOOD PRESSURE; VISUAL ANALOG SCALE; VITAL SIGN; WAKEFULNESS; WILD TYPE;

ADMINISTRATION, ORAL; ADULT; ALCOHOL DEHYDROGENASE; AREA UNDER CURVE; BLOOD PRESSURE; BUTYLENE GLYCOLS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HALF-LIFE; HAPLOTYPES; HUMANS; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; OXIMETRY; OXYGEN; PHARMACOLOGY, CLINICAL; SODIUM OXYBATE; TIME FACTORS;

EID: 33846592302     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/sj.clpt.6100037     Document Type: Article

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