Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with "in-vial" derivatization and headspace-trap gas chromatography-mass spectrometry

Journal of Chromatography A

Volumn 1296, Issue , 2013, Pages 84-92

  Ingels, Ann Sofie M E ^a,d   Neels, Hugo ^b,c   Lambert, Willy E ^a   Stove, Christophe P ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c Stuivenberg General Hospital   (Belgium)

^d National Institute of Criminalistics and Criminology   (Belgium)

Author keywords

Biological matrices; Gamma hydroxybutyric acid (GHB); Gas chromatography coupled to mass spectrometry (GC MS); Headspace trap (HS trap); In vial derivatization; Toxicology

Indexed keywords

BIOLOGICAL MATRIXES; DERIVATIZATIONS; GAMMA-HYDROXYBUTYRIC ACID (GHB); GAS CHROMATOGRAPHY COUPLED TO MASS SPECTROMETRIES (GC MS); HEADSPACE-TRAP (HS-TRAP); TOXICOLOGY;

ALKYLATION; BLOOD; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMAS;

CALIBRATION;

4 HYDROXYBUTYRIC ACID;

ACCURACY; ANALYTIC METHOD; ARTICLE; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; DERIVATIZATION; DRUG DETERMINATION; HEAD STRAP GAS CHROMATOGRAPHY MASS SPECTROMETRY; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; QUALITY CONTROL; REPRODUCIBILITY; TEMPERATURE SENSITIVITY; URINALYSIS; VALIDATION PROCESS;

ANALYSIS OF VARIANCE; CHEMICAL FRACTIONATION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYBUTYRATES; REPRODUCIBILITY OF RESULTS; SULFATES; TEMPERATURE;

EID: 84878695123     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.04.023     Document Type: Article

References (34)

1. Smith R.M. J. Chromatogr. A 2003, 1000:3.
2. Wille S.M., Lambert W.E. Anal. Bioanal. Chem. 2007, 388:1381.
3. Røen B.T., Unneberg E., Tørnes J.A.A., Lundanes E. J. Chromatogr. A 2010, 1217:761.
4. Schulz K., Dreβler J., Sohnius E.M., Lachenmeier D.W. J. Chromatogr. A 2007, 1145:204.
5. Røen B.T., Unneberg E., Tørnes J.Aa., Lundanes E. J. Chromatogr. A 2010, 1217:2171.
6. Nikfardjam M.P., Maier D. Food Chem. 2011, 126:1926.
7. Aberl A., Coelhan M. J. Agric. Food Chem. 2012, 60:2785.
8. Zvosec D.L., Smith S.W., Porrata T., Strobl A.Q., Dyer J.E. Am. J. Emerg. Med. 2011, 29(3):319.
9. Van Amsterdam J.G.C., Brunt T.M., McMaster M.T.B., Niesink R.J.M. Neurosci. Biobehav. Rev. 2012, 36:1217.
10. Dahl S.R., Olsen K.M., Strand D.H. J. Chromatogr. B 2012, 885-886:37.
11. Morris-Kukoski C.L. Toxicol. Rev. 2004, 23:33.
12. Van hee P., Neels H., De Doncker M., Vrydags N., Schatteman K., Uyttenbroeck W., Hamers N., Himpe D., Lambert W.E. Clin. Chem. Lab. Med. 2004, 42:1341.
13. Meyer M.R., Weber A.A., Maurer H.H. Anal. Bioanal. Chem. 2011, 400:411.
14. Ingels A.S., Lambert W.E., Stove C.P. Anal. Bioanal. Chem. 2010, 398:2173.
15. Ingels A.S., De Paepe P., Anseeuw K., Van Sassenbroeck D., Neels H., Lambert W., Stove C. Bioanalysis 2011, 3:2271.
16. LeBeau M.A., Montgomery M.A., Miller M.L., Burmeister S.G. J. Anal. Toxicol. 2000, 24:421.
17. Frison G., Tedeschi L., Maietti S., Ferrara S.D. Rapid Commun. Mass Spectrosc. 2000, 14:2401.
18. Lenz D., Kröner L., Rothschild M.A. J. Chromatogr. A 2009, 1216:4090.
19. Blair S., Song M., Hall B., Brodbelt J. J. Forensic Sci. 2001, 46:688.
20. Brown S.D., Rhodes D.J., Pritchard B.J. Forensic Sci. Int. 2007, 171:142.
21. Harvey S.D., Wahl J.H. J. Chromatogr. A 2012, 1256:58.
22. Barani F., Dell'Amico N., Griffone L., Santoro M., Tarabella C. J. Chromatogr. Sci. 2006, 44:625.
23. Rasanen I., Viinamäki J., Vuori E., Ojanperä I. J. Anal. Toxicol. 2010, 34:113.
24. Kolb B., Ettre L.S. Static Headspace - Gas Chromatography: Theory and Practice 2006, John Wiley and Sons Inc., Hoboken, NJ. 2nd edition.
25. EMA Guideline on Bioanalytical Method Validation, Committee for Medicinal Products for Human Use (CHMP), 21 July 2011, . http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf.
26. Wille S.M.R., Peters F.T., Di Fazio V., Samyn N. Acc. Qual. Assur. 2011, 16:279.
27. Cardador M.J., Gallego M. Anal. Bioanal. Chem. 2010, 396:1331.
28. Ciolini L.A., Mesmer M.Z., Satzger R.D., Machal A.C., McCauley H.A., Mohrhaus A.S. J. Forensic Sci. 2001, 46:1315.
29. Roberts D.M., Smith M.W., Gopalakrishnan M., Whittaker G., Day R.O. Ann. Emerg. Med. 2011, 58(1):83.
30. Elliott S.P. Ther. Drug Monit. 2004, 26(4):432.
31. Andresen H., Sprys N., Schmoldt A., Mueller A., Iwersen-Bergmann S. Forensic Sci. Int. 2010, 200:93.
32. LeBeau M.A., Montgomery M.A. Forensic Sci. Int. 2011, 207:e61.
33. Elian A.A. Forensic Sci. Int. 2002, 128:120.
34. Elliott S.P. Forensic Sci. Int. 2003, 133:9.