Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct "on spot" derivatization

Analytical and Bioanalytical Chemistry

Volumn 398, Issue 5, 2010, Pages 2173-2182

  Ingels, Ann Sofie M E ^a   Lambert, Willy E ^a   Stove, Christophe P ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Direct derivatization; Dried blood spots (DBS); Gamma hydroxybutyric acid (GHB); Gas chromatography mass spectrometry (GC MS); Method validation

Indexed keywords

DERIVATIZATIONS; DRIED BLOOD SPOTS (DBS); GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS); HYDROXYBUTYRIC ACIDS; METHOD VALIDATIONS;

ACIDS; BLOOD; MASS SPECTROMETRY;

GAS CHROMATOGRAPHY;

4 HYDROXYBUTYRIC ACID; 4-HYDROXYBUTYRIC ACID; HYDROXYBUTYRIC ACID;

ARTICLE; BLOOD; BLOOD SAMPLING; HUMAN; MASS FRAGMENTOGRAPHY; METHODOLOGY; TIME;

BLOOD SPECIMEN COLLECTION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYBUTYRATES; TIME FACTORS;

EID: 78049347658     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4183-9     Document Type: Article

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