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Volumn 902, Issue , 2012, Pages 15-27

LC-MS vs. GC-MS, online extraction systems, advantages of technology for drug screening assays

Author keywords

GC MS; General unknown screening; LC MS; Mass spectral libraries; Systematic toxicological analysis

Indexed keywords

DRUG;

EID: 84865321351     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-934-1_2     Document Type: Article
Times cited : (22)

References (42)
  • 1
    • 77952951757 scopus 로고    scopus 로고
    • Perspectives of liquid chromatography coupled to low-and high-resolution mass spectrometry for screening, identi fi cation, and quanti fi cation of drugs in clinical and forensic toxicology
    • Maurer HH (2010) Perspectives of liquid chromatography coupled to low-and high-resolution mass spectrometry for screening, identi fi cation, and quanti fi cation of drugs in clinical and forensic toxicology. Ther Drug Monit 32:324-327
    • (2010) Ther Drug Monit , vol.32 , pp. 324-327
    • Maurer, H.H.1
  • 2
    • 78650864016 scopus 로고    scopus 로고
    • Recent advances of liquid chromatography-(tandem) mass spectrometry in clinical and forensic toxicology
    • Peters FT (2010) Recent advances of liquid chromatography-(tandem) mass spectrometry in clinical and forensic toxicology. Clin Biochem 44(1):54-65
    • (2010) Clin Biochem , vol.44 , Issue.1 , pp. 54-65
    • Peters, F.T.1
  • 3
    • 79958850026 scopus 로고    scopus 로고
    • Fragmentation of toxicologically relevant drugs in positive-ion liquid chromatography-tandem mass spectrometry
    • Niessen WM (2011) Fragmentation of toxicologically relevant drugs in positive-ion liquid chromatography-tandem mass spectrometry. Mass Spectrom Rev 30(4):626-63
    • (2011) Mass Spectrom Rev , vol.30 , Issue.4 , pp. 626-663
    • Niessen, W.M.1
  • 4
    • 51349162644 scopus 로고    scopus 로고
    • Pitfalls and prevention strategies for liquid chromatography-tandem mass spectrometry in the selected reaction-monitoring mode for drug analysis
    • Sauvage FL, Gaulier JM, Lachâtre G, Marquet P (2008) Pitfalls and prevention strategies for liquid chromatography-tandem mass spectrometry in the selected reaction-monitoring mode for drug analysis. Clin Chem 54(9):1519-1527
    • (2008) Clin Chem , vol.54 , Issue.9 , pp. 1519-1527
    • Sauvage, F.L.1    Gaulier, J.M.2    Lachâtre, G.3    Marquet, P.4
  • 5
    • 77950570852 scopus 로고    scopus 로고
    • Automated mass spectral deconvolution and identi fi cation system for GC-MS screening for drugs, poisons, and metabolites in urine
    • Meyer MR, Peters FT, Maurer HH (2010) Automated mass spectral deconvolution and identi fi cation system for GC-MS screening for drugs, poisons, and metabolites in urine. Clin Chem 56(4):575-584
    • (2010) Clin Chem , vol.56 , Issue.4 , pp. 575-584
    • Meyer, M.R.1    Peters, F.T.2    Maurer, H.H.3
  • 6
    • 65349094639 scopus 로고    scopus 로고
    • Validation of the direct analysis in real time source for use in forensic drug screening
    • Steiner RR, Larson RL (2009) Validation of the direct analysis in real time source for use in forensic drug screening. J Forensic Sci 54(3):617-622
    • (2009) J Forensic Sci , vol.54 , Issue.3 , pp. 617-622
    • Steiner, R.R.1    Larson, R.L.2
  • 7
    • 0036146706 scopus 로고    scopus 로고
    • Is LC-MS suitable for a comprehensive screening of drugs and poisons in clinical toxicology?
    • Marquet P (2002) Is LC-MS suitable for a comprehensive screening of drugs and poisons in clinical toxicology? Ther Drug Monit 24:125-133
    • (2002) Ther Drug Monit , vol.24 , pp. 125-133
    • Marquet, P.1
  • 8
    • 70049107962 scopus 로고    scopus 로고
    • Systematic toxicological analysis with LC-MS
    • Polettini A (ed) Pharmaceutical Press, London
    • Marquet P (2006) Systematic toxicological analysis with LC-MS. In: Polettini A (ed) Applications of LC-MS in toxicology. Pharmaceutical Press, London
    • (2006) Applications of LC-MS in Toxicology
    • Marquet, P.1
  • 9
  • 10
    • 0142043007 scopus 로고    scopus 로고
    • Simultaneous screening for 238 drugs in blood by liquid chromatography-ionspray tandem mass spectrometry with multiple-reaction monitoring
    • Gergov M, Ojanperä I, Vuori E (2003) Simultaneous screening for 238 drugs in blood by liquid chromatography-ionspray tandem mass spectrometry with multiple-reaction monitoring. J Chromatogr B 795:41-53
    • (2003) J Chromatogr B , vol.795 , pp. 41-53
    • Gergov, M.1    Ojanperä, I.2    Vuori, E.3
  • 11
    • 77951258597 scopus 로고    scopus 로고
    • Detection and identi fi cation of 700 drugs by multi-target screening with a 3200 QTRAP ® LC-MS-MS system and library searching
    • Dresen S, Ferreirós N, Gnann H, Zimmermann R, Weinmann W (2010) Detection and identi fi cation of 700 drugs by multi-target screening with a 3200 QTRAP ® LC-MS-MS system and library searching. Anal Bioanal Chem 396:2425-2434
    • (2010) Anal Bioanal Chem , vol.396 , pp. 2425-2434
    • Dresen, S.1    Ferreirós, N.2    Gnann, H.3    Zimmermann, R.4    Weinmann, W.5
  • 12
    • 77949263106 scopus 로고    scopus 로고
    • ESI-MS-MS library of 1,253 compounds for application in forensic and clinical toxicology
    • Sauvage FL, Marquet P (2010) ESI-MS-MS library of 1,253 compounds for application in forensic and clinical toxicology. Anal Bioanal Chem 396(5):1947
    • (2010) Anal Bioanal Chem , vol.396 , Issue.5 , pp. 1947
    • Sauvage, F.L.1    Marquet, P.2
  • 13
    • 70450176003 scopus 로고    scopus 로고
    • General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: Applications and constraints
    • Sauvage FL, Picard N, Saint-Marcoux F, Gaulier JM, Lachâtre G, Marquet P (2009) General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: applications and constraints. J Sep Sci 32(18):3074-3083
    • (2009) J Sep Sci , vol.32 , Issue.18 , pp. 3074-3083
    • Sauvage, F.L.1    Picard, N.2    Saint-Marcoux, F.3    Gaulier, J.M.4    Lachâtre, G.5    Marquet, P.6
  • 14
    • 0037420914 scopus 로고    scopus 로고
    • Comparison of a preliminary procedure for the general unknown screening of drugs and toxic compounds using a quadrupole-linear ion-trap mass spectrometer with a liquid chromatography-mass spectrometry reference technique
    • Marquet P, Saint-Marcoux F, Gamble TN, Leblanc JCY (2003) Comparison of a preliminary procedure for the general unknown screening of drugs and toxic compounds using a quadrupole-linear ion-trap mass spectrometer with a liquid chromatography-mass spectrometry reference technique. J Chromatogr 789:9-18
    • (2003) J Chromatogr , vol.789 , pp. 9-18
    • Marquet, P.1    Saint-Marcoux, F.2    Gamble, T.N.3    Leblanc, J.C.Y.4
  • 15
    • 33748316481 scopus 로고    scopus 로고
    • Screening of drugs and toxic compounds with liquid chromatography-linear ion trap tandem mass spectrometry
    • Sauvage FL, Saint-Marcoux F, Duretz B, Deporte D, Lachatre G, Marquet P (2006) Screening of drugs and toxic compounds with liquid chromatography-linear ion trap tandem mass spectrometry. Clin Chem 52(9):1735-1742
    • (2006) Clin Chem , vol.52 , Issue.9 , pp. 1735-1742
    • Sauvage, F.L.1    Saint-Marcoux, F.2    Duretz, B.3    Deporte, D.4    Lachatre, G.5    Marquet, P.6
  • 16
    • 0034446189 scopus 로고    scopus 로고
    • MS-MS Libraries with triple quadrupole MS-MS for drug identi fi cation and drug screening
    • Weinmann W, Gergov M, Goerner M (2000) MS-MS Libraries with triple quadrupole MS-MS for drug identi fi cation and drug screening. Analysis 28:934-941
    • (2000) Analysis , vol.28 , pp. 934-941
    • Weinmann, W.1    Gergov, M.2    Goerner, M.3
  • 17
    • 3042696846 scopus 로고    scopus 로고
    • Reproducible product-ion tandem mass spectra on various liquid chromatography-mass spectrometry instruments for the development of spectral libraries
    • Bristow AWT, Webb KS, Lubben AT, Halket J (2004) Reproducible product-ion tandem mass spectra on various liquid chromatography-mass spectrometry instruments for the development of spectral libraries. Rapid Commun Mass Spectrom 18:1447-1454
    • (2004) Rapid Commun Mass Spectrom , vol.18 , pp. 1447-1454
    • Bristow, A.W.T.1    Webb, K.S.2    Lubben, A.T.3    Halket, J.4
  • 18
    • 1842428022 scopus 로고    scopus 로고
    • Creation and comparison of MS-MS spectral libraries using quadrupole ion trap and triple-quadrupole mass spectrometer
    • Josephs JL, Sanders M (2004) Creation and comparison of MS-MS spectral libraries using quadrupole ion trap and triple-quadrupole mass spectrometer. Rapid Commun Mass Spectrom 18:743-759
    • (2004) Rapid Commun Mass Spectrom , vol.18 , pp. 743-759
    • Josephs, J.L.1    Sanders, M.2
  • 19
    • 14844312890 scopus 로고    scopus 로고
    • LC-MS-MS systematic toxicological analysis: Comparison of MS-MS spectra obtained with different instruments and settings
    • Jansen R, Lachâtre G, Marquet P (2005) LC-MS-MS systematic toxicological analysis: comparison of MS-MS spectra obtained with different instruments and settings. Clin Biochem 38:362-372
    • (2005) Clin Biochem , vol.38 , pp. 362-372
    • Jansen, R.1    Lachâtre, G.2    Marquet, P.3
  • 20
    • 25644437012 scopus 로고    scopus 로고
    • Towards a full reference library of MS n spectra. Testing a library containing 3126 MS 2 spectra of 1743 compounds
    • Milman BL (2005) Towards a full reference library of MS n spectra. Testing a library containing 3126 MS 2 spectra of 1743 compounds. Rapid Commun Mass Spectrom 19:2833-2839
    • (2005) Rapid Commun Mass Spectrom , vol.19 , pp. 2833-2839
    • Milman, B.L.1
  • 21
    • 65649117746 scopus 로고    scopus 로고
    • On the inter-instrument and interlaboratory transferability of a tandem mass spectral reference library: 1. Results of an Austrian multicenter study
    • Oberacher H, Pavlic M, Libiseller K, Schubert B, Sulyok M, Schuhmacher R, Csaszar E, Köfeler HC (2009) On the inter-instrument and interlaboratory transferability of a tandem mass spectral reference library: 1. Results of an Austrian multicenter study. J Mass Spectrom 44:485-493
    • (2009) J Mass Spectrom , vol.44 , pp. 485-493
    • Oberacher, H.1    Pavlic, M.2    Libiseller, K.3    Schubert, B.4    Sulyok, M.5    Schuhmacher, R.6    Csaszar, E.7    Köfeler, H.C.8
  • 22
    • 65649115837 scopus 로고    scopus 로고
    • On the inter-instrument and the inter-laboratory transferability of a tandem mass spectral reference library: 2. Optimization and characterization of the search algorithm
    • Oberacher H, Pavlic M, Libiseller K, Schubert B, Sulyok M, Schuhmacher R, Csaszar E, Köfeler HC (2009) On the inter-instrument and the inter-laboratory transferability of a tandem mass spectral reference library: 2. Optimization and characterization of the search algorithm. J Mass Spectrom 44:494-502
    • (2009) J Mass Spectrom , vol.44 , pp. 494-502
    • Oberacher, H.1    Pavlic, M.2    Libiseller, K.3    Schubert, B.4    Sulyok, M.5    Schuhmacher, R.6    Csaszar, E.7    Köfeler, H.C.8
  • 23
    • 0034051112 scopus 로고    scopus 로고
    • A library of atmospheric pressure ionization daughter ion mass spectra based on wideband excitation in an ion trap mass spectrometer
    • Baumann C, Cintora MA, Eichler M, Lifante E, Cooke M, Przyborowska A, Halket JM (2000) A library of atmospheric pressure ionization daughter ion mass spectra based on wideband excitation in an ion trap mass spectrometer. Rapid Commun Mass Spectrom 14:349-356
    • (2000) Rapid Commun Mass Spectrom , vol.14 , pp. 349-356
    • Baumann, C.1    Cintora, M.A.2    Eichler, M.3    Lifante, E.4    Cooke, M.5    Przyborowska, A.6    Halket, J.M.7
  • 24
    • 77951296143 scopus 로고    scopus 로고
    • Screening of pesticides in blood with liquid chromatography-linear ion trap mass spectrometry
    • Dulaurent S, Moesch C, Marquet P, Gaulier JM, Lachâtre G (2010) Screening of pesticides in blood with liquid chromatography-linear ion trap mass spectrometry. Anal Bioanal Chem 396(6):2235-2249
    • (2010) Anal Bioanal Chem , vol.396 , Issue.6 , pp. 2235-2249
    • Dulaurent, S.1    Moesch, C.2    Marquet, P.3    Gaulier, J.M.4    Lachâtre, G.5
  • 25
    • 0035029350 scopus 로고    scopus 로고
    • Toxicological screening of urine for drugs by liquid chromatography/time- of-flight mass spectrometry with automated target library search based on elemental formulas
    • Gergov M, Boucher B, Ojanperä I, Vuori E (2001) Toxicological screening of urine for drugs by liquid chromatography/time-of-flight mass spectrometry with automated target library search based on elemental formulas. Rapid Commun Mass Spectrom 15:521-526
    • (2001) Rapid Commun Mass Spectrom , vol.15 , pp. 521-526
    • Gergov, M.1    Boucher, B.2    Ojanperä, I.3    Vuori, E.4
  • 26
    • 0242322764 scopus 로고    scopus 로고
    • Toxicological screening with formula-based metabolite identi fi cation by liquid chromatography/time-of-flight mass spectrometry
    • Pelander A, Ojanperä I, Laks S, Rasanen I, Vuori E (2003) Toxicological screening with formula-based metabolite identi fi cation by liquid chromatography/time-of-flight mass spectrometry. Anal Chem 75:5710-5718
    • (2003) Anal Chem , vol.75 , pp. 5710-5718
    • Pelander, A.1    Ojanperä, I.2    Laks, S.3    Rasanen, I.4    Vuori, E.5
  • 27
    • 33645510278 scopus 로고    scopus 로고
    • Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time-offlight mass spectrometry
    • Ojanperä S, Pelander A, Pelzing M, Krebs I, Vuori E, Ojanperä I (2006) Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time-offlight mass spectrometry. Rapid Commun Mass Spectrom 20:1161-1167
    • (2006) Rapid Commun Mass Spectrom , vol.20 , pp. 1161-1167
    • Ojanperä, S.1    Pelander, A.2    Pelzing, M.3    Krebs, I.4    Vuori, E.5    Ojanperä, I.6
  • 28
    • 33846624349 scopus 로고    scopus 로고
    • A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-offlight mass spectrometry
    • Kolmonen M, Leinonen A, Pelander A, Ojanperä I (2007) A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-offlight mass spectrometry. Anal Chim Acta 585(1):94-102
    • (2007) Anal Chim Acta , vol.585 , Issue.1 , pp. 94-102
    • Kolmonen, M.1    Leinonen, A.2    Pelander, A.3    Ojanperä, I.4
  • 29
    • 68049135677 scopus 로고    scopus 로고
    • Development of a broad toxicological screening technique for urine using ultra-performance liquid chromatography and time-of-flight mass spectrometry
    • Lee HK, Ho CS, Iu YP, Lai PS, Shek CC, Lo Y-C, Klinke HB, Wood M (2009) Development of a broad toxicological screening technique for urine using ultra-performance liquid chromatography and time-of-flight mass spectrometry. Anal Chim Acta 649:80-90
    • (2009) Anal Chim Acta , vol.649 , pp. 80-90
    • Lee, H.K.1    Ho, C.S.2    Iu, Y.P.3    Lai, P.S.4    Shek, C.C.5    Lo, Y.-C.6    Klinke, H.B.7    Wood, M.8
  • 30
    • 64649083661 scopus 로고    scopus 로고
    • Fast analysis of doping agents in urine by ultra-highpressure liquid chromatography-quadrupole time-of-flight mass spectrometry I. Screening analysis
    • Badoud F, Grata E, Perrenoud L, Avois L, Saugy M, Rudaz S, Veuthey JL (2009) Fast analysis of doping agents in urine by ultra-highpressure liquid chromatography-quadrupole time-of-flight mass spectrometry I. Screening analysis. J Chromatogr A 1216:4423-4433
    • (2009) J Chromatogr A , vol.1216 , pp. 4423-4433
    • Badoud, F.1    Grata, E.2    Perrenoud, L.3    Avois, L.4    Saugy, M.5    Rudaz, S.6    Veuthey, J.L.7
  • 32
    • 77951258674 scopus 로고    scopus 로고
    • Generic sample preparation combined with high-resolution liquid chromatography-time-of-flight mass spectrometry for uni fi cation of urine screening in doping-control laboratories
    • Peters RJ, Oosterink JE, Stolker AA, Georgakopoulos C, Nielen MW (2010) Generic sample preparation combined with high-resolution liquid chromatography-time-of-flight mass spectrometry for uni fi cation of urine screening in doping-control laboratories. Anal Bioanal Chem 396:2583-2598
    • (2010) Anal Bioanal Chem , vol.396 , pp. 2583-2598
    • Peters, R.J.1    Oosterink, J.E.2    Stolker, A.A.3    Georgakopoulos, C.4    Nielen, M.W.5
  • 33
    • 60549107218 scopus 로고    scopus 로고
    • In silico methods for predicting metabolism and mass fragmentation applied to quetiapine in liquid chromatography/time-of-flight mass spectrometry urine drug screening
    • Pelander A, Tyrkkö E, Ojanperä I (2009) In silico methods for predicting metabolism and mass fragmentation applied to quetiapine in liquid chromatography/time-of-flight mass spectrometry urine drug screening. Rapid Commun Mass Spectrom 23(4):506-514
    • (2009) Rapid Commun Mass Spectrom , vol.23 , Issue.4 , pp. 506-514
    • Pelander, A.1    Tyrkkö, E.2    Ojanperä, I.3
  • 34
    • 42349110546 scopus 로고    scopus 로고
    • Implementation and performance evaluation of a database of chemical formulas for the screening of pharmaco/toxicologically relevant compounds in biological samples using electrospray ionization-time-of-flight mass spectrometry
    • Polettini A, Gottardo R, Pascali JP, Tagliaro F (2008) Implementation and performance evaluation of a database of chemical formulas for the screening of pharmaco/toxicologically relevant compounds in biological samples using electrospray ionization-time-of-flight mass spectrometry. Anal Chem 80:3050-3057
    • (2008) Anal Chem , vol.80 , pp. 3050-3057
    • Polettini, A.1    Gottardo, R.2    Pascali, J.P.3    Tagliaro, F.4
  • 35
    • 47749089748 scopus 로고    scopus 로고
    • Introduction of HPLC/orbitrap mass spectrometry as screening method for doping control
    • Virus ED, Sobolevsky TG, Rodchenkov GM (2008) Introduction of HPLC/orbitrap mass spectrometry as screening method for doping control. J Mass Spectrom 43:949-957
    • (2008) J Mass Spectrom , vol.43 , pp. 949-957
    • Virus, E.D.1    Sobolevsky, T.G.2    Rodchenkov, G.M.3
  • 37
    • 60649086153 scopus 로고    scopus 로고
    • Full-scan accurate mass selectivity of ultra-performance liquid chromatography combined with time-of-flight and orbitrap mass spectrometry in hormone and veterinary drug residue analysis
    • van der Heeft E, Bolck YJ, Beumer B, Nijrolder AW, Stolker AA, Nielen MW (2009) Full-scan accurate mass selectivity of ultra-performance liquid chromatography combined with time-of-flight and orbitrap mass spectrometry in hormone and veterinary drug residue analysis. J Am Soc Mass Spectrom 20(3):451-463
    • (2009) J Am Soc Mass Spectrom , vol.20 , Issue.3 , pp. 451-463
    • Van Der Heeft, E.1    Bolck, Y.J.2    Beumer, B.3    Nijrolder, A.W.4    Stolker, A.A.5    Nielen, M.W.6
  • 38
    • 77953476888 scopus 로고    scopus 로고
    • New trends in fast and high-resolution liquid chromatography: A critical comparison of existing approaches
    • Guillarme D, Ruta J, Rudaz S, Veuthey JL (2010) New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches. Anal Bioanal Chem 397:1069-1082
    • (2010) Anal Bioanal Chem , vol.397 , pp. 1069-1082
    • Guillarme, D.1    Ruta, J.2    Rudaz, S.3    Veuthey, J.L.4
  • 39
    • 77955050026 scopus 로고    scopus 로고
    • Performance evaluation of three liquid chromatography mass spectrometry methods for broad spectrum drug screening
    • Lynch KL, Breaud AR, Vandenberghe H, Wu AH, Clarke W (2010) Performance evaluation of three liquid chromatography mass spectrometry methods for broad spectrum drug screening. Clin Chim Acta 411(19-20):1474-1481
    • (2010) Clin Chim Acta , vol.411 , Issue.19-20 , pp. 1474-1481
    • Lynch, K.L.1    Breaud, A.R.2    Vandenberghe, H.3    Wu, A.H.4    Clarke, W.5
  • 40
    • 29144511543 scopus 로고    scopus 로고
    • Investigation of an LC-MS-MS (QTrap) method for the rapid screening and identi fi cation of drugs in postmortem toxicology whole blood samples
    • Herrin GL, McCurdy HH, Wall WH (2005) Investigation of an LC-MS-MS (QTrap) method for the rapid screening and identi fi cation of drugs in postmortem toxicology whole blood samples. J Anal Toxicol 29(7):599-606
    • (2005) J Anal Toxicol , vol.29 , Issue.7 , pp. 599-606
    • Herrin, G.L.1    McCurdy, H.H.2    Wall, W.H.3
  • 41
    • 34548691464 scopus 로고    scopus 로고
    • A direct screening procedure for diuretics in human urine by liquid chromatography-tandem mass spectrometry with information dependent acquisition
    • Politi L, Morini L, Polettini A (2007) A direct screening procedure for diuretics in human urine by liquid chromatography-tandem mass spectrometry with information dependent acquisition. Clin Chim Acta 386(1-2): 46-52
    • (2007) Clin Chim Acta , vol.386 , Issue.1-2 , pp. 46-52
    • Politi, L.1    Morini, L.2    Polettini, A.3
  • 42
    • 77950159881 scopus 로고    scopus 로고
    • Recent advances in microextraction by packed sorbent for bioanalysis
    • Abdel-Rehim M (2010) Recent advances in microextraction by packed sorbent for bioanalysis. J Chromatogr A 1217(16):2569-2580
    • (2010) J Chromatogr A , vol.1217 , Issue.16 , pp. 2569-2580
    • Abdel-Rehim, M.1


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