Quantitation of gamma-hydroxybutyric acid in dried blood spots in newborn screening

Molecular Genetics and Metabolism

Volumn 110, Issue 1-2, 2013, Pages 195-

  Stove, Christophe P ^a   Ingels, Ann Sofie M E ^a   Lambert, Willy E ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBUTYRIC ACID; HYDROXYBUTYRIC ACID; SUCCINATE SEMIALDEHYDE DEHYDROGENASE;

CALIBRATION; DRIED BLOOD SPOT TESTING; HUMAN; LETTER; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; NEWBORN; NEWBORN SCREENING; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; BLOOD; DEFICIENCY;

HUMANS; HYDROXYBUTYRATES; NEONATAL SCREENING; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE;

EID: 84882773842     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2013.06.009     Document Type: Letter

References (5)

1. Forni S., Pearl P.L., Gibson K.M., Yu Y., Sweetman L. Quantitation of gamma-hydroxybutyric acid in dried blood spots: feasibility assessment for newborn screening of succinic semialdehyde dehydrogenase (SSADH) deficiency. Mol. Genet. Metab. 2013, 109:255-259.
2. Ingels A.M.E., Lambert W.E., Stove C.P. Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct "on spot" derivatization. Anal. Bioanal. Chem. 2010, 398:2173-2182.
3. Ingels A.S., De Paepe P., Anseeuw K., Van Sassenbroeck D.K., Neels H., Lambert W.E., Stove C.P. Dried blood spot punches for confirmation of suspected gamma-hydroxybutyric acid intoxications: validation of an optimized GC-MS procedure. Bioanalysis 2011, 3:2271-2281.
4. Sørensen L.K., Hasselstrøm J.B. A hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry method for the simultaneous determination of γ-hydroxybutyrate and its precursors in forensic whole blood. Forensic Sci. Int. 2012, 222:352-359.
5. Dahl S.R., Olsen K.M., Strand D.H. Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2012, 885-886:37-42.