Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland

PLoS Genetics

Volumn 10, Issue 5, 2014, Pages

  Godde, Nathan J ^a,b   Sheridan, Julie M ^b,c   Smith, Lorey K ^a,b   Pearson, Helen B ^a,b   Britt, Kara L ^a,b   Galea, Ryan C ^a,b   Yates, Laura L ^a,b   Visvader, Jane E ^b,c   Humbert, Patrick O ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SCRIBBLE PROTEIN; TRANSCRIPTION FACTOR FRA 1; UNCLASSIFIED DRUG; PROTEIN C FOS; SCRIBBLE PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APICAL MEMBRANE; APOPTOSIS; ARTICLE; BASOLATERAL MEMBRANE; BREAST DEVELOPMENT; BREAST DUCT; BREAST HYPERPLASIA; BREAST TUMOR; CANCER GROWTH; CANCER INHIBITION; CELL EXPANSION; CELL FATE; CELL POLARITY; CLONOGENESIS; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE LOSS; IN VIVO STUDY; MALE; MORPHOGENESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCRIB GENE; STEM CELL; ANIMAL; EXPERIMENTAL MAMMARY NEOPLASM; HOMEOSTASIS; HYPERPLASIA; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; UDDER;

ANIMALS; CELL POLARITY; FEMALE; HOMEOSTASIS; HYPERPLASIA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MAP KINASE SIGNALING SYSTEM; MICE; MORPHOGENESIS; PROTO-ONCOGENE PROTEINS C-FOS;

EID: 84901625046     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004323     Document Type: Article

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