An MRAS, SHOC2, and SCRIB complex coordinates erk pathway activation with polarity and tumorigenic growth

Molecular Cell

Volumn 52, Issue 5, 2013, Pages 679-692

  Young, LucyC ^a   Hartig, Nicole ^a   Muñoz Alegre, Marta ^a   Oses Prieto, JuanA ^b   Durdu, Sevi ^c   Bender, Sabine ^a   Vijayakumar, Vineetha ^d   VietriRudan, Matteo ^a   Gewinner, Christina ^a   Henderson, Stephen ^a   Jathoul, AmitP ^a   Ghatrora, Rupinder ^e   Lythgoe, MarkF ^e   Burlingame, AlmaL ^b   Rodriguez Viciana, Pablo ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HOLOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MRAS PROTEIN; PP1 PROTEIN; RAF PROTEIN; RAS PROTEIN; REGULATOR PROTEIN; SCRIB PROTEIN; SHOC2 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CELL POLARITY; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH;

CARCINOGENESIS; CELL LINE; CELL MOVEMENT; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROMOLECULAR SUBSTANCES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; PHOSPHORYLATION; RAF KINASES; RAS PROTEINS; RECEPTORS, NEUROPEPTIDE Y; TUMOR SUPPRESSOR PROTEINS;

EID: 84890205665     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2013.10.004     Document Type: Article

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