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Volumn 9, Issue 11, 2008, Pages 887-901

From cells to organs: Building polarized tissue

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; SCATTER FACTOR; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN;

EID: 54549091120     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm2523     Document Type: Review
Times cited : (633)

References (149)
  • 1
    • 0036636095 scopus 로고    scopus 로고
    • Building epithelial architecture: Insights from three-dimensional culture models
    • O'Brien, L. E., Zegers, M. M. & Mostov, K. E. Building epithelial architecture: insights from three-dimensional culture models. Nature Rev. Mol. Cell Biol. 3, 531-537 (2002).
    • (2002) Nature Rev. Mol. Cell Biol , vol.3 , pp. 531-537
    • O'Brien, L.E.1    Zegers, M.M.2    Mostov, K.E.3
  • 2
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: Fundamental players in animal cell polarization
    • Goldstein, B. & Macara, I. G. The PAR proteins: fundamental players in animal cell polarization. Dev. Cell 13, 609-622 (2007).
    • (2007) Dev. Cell , vol.13 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 3
    • 0037452071 scopus 로고    scopus 로고
    • Adaptation of core mechanisms to generate cell polarity
    • Nelson, W. J. Adaptation of core mechanisms to generate cell polarity. Nature 422, 766-774 (2003).
    • (2003) Nature , vol.422 , pp. 766-774
    • Nelson, W.J.1
  • 4
    • 36048998478 scopus 로고    scopus 로고
    • Orchestrating size and shape during morphogenesis
    • Lecuit, T. & Le Goff, L. Orchestrating size and shape during morphogenesis. Nature 450, 189-192 (2007).
    • (2007) Nature , vol.450 , pp. 189-192
    • Lecuit, T.1    Le Goff, L.2
  • 6
    • 32544432516 scopus 로고    scopus 로고
    • Tight junctions: Molecular architecture and function
    • Aijaz, S., Balda, M. S. & Matter, K. Tight junctions: molecular architecture and function. Int. Rev. Cytol. 248, 261-298 (2006).
    • (2006) Int. Rev. Cytol , vol.248 , pp. 261-298
    • Aijaz, S.1    Balda, M.S.2    Matter, K.3
  • 8
    • 47749146582 scopus 로고    scopus 로고
    • Building the cell: Design principles of cellular architecture
    • Rafelski, S. M. & Marshall, W. F. Building the cell: design principles of cellular architecture. Nature Rev. Mol. Cell Biol. 9, 593-602 (2008).
    • (2008) Nature Rev. Mol. Cell Biol , vol.9 , pp. 593-602
    • Rafelski, S.M.1    Marshall, W.F.2
  • 9
    • 34447515984 scopus 로고    scopus 로고
    • Synapses: Sites of cell recognition, adhesion, and functional specification
    • Yamada, S. & Nelson, W. J. Synapses: sites of cell recognition, adhesion, and functional specification. Annu. Rev. Biochem. 76, 267-294 (2007).
    • (2007) Annu. Rev. Biochem , vol.76 , pp. 267-294
    • Yamada, S.1    Nelson, W.J.2
  • 11
    • 0037235163 scopus 로고    scopus 로고
    • Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila
    • Deng, W. M. et al. Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila. Development 130, 173-184 (2003).
    • (2003) Development , vol.130 , pp. 173-184
    • Deng, W.M.1
  • 12
    • 12844272106 scopus 로고    scopus 로고
    • β1-integrin orients epithelial polarity via Rac1 and laminin
    • Outlines, together with references 37 and 38, the importance of ECM-integrin-Rac signalling in the orientation of polarity
    • Yu, W. et al. β1-integrin orients epithelial polarity via Rac1 and laminin. Mol. Biol. Cell 16, 433-445 (2005). Outlines, together with references 37 and 38, the importance of ECM-integrin-Rac signalling in the orientation of polarity.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 433-445
    • Yu, W.1
  • 13
    • 34548403115 scopus 로고    scopus 로고
    • Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis
    • Kass, L., Erler, J. T., Dembo, M. & Weaver, V. M. Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Int. J. Biochem. Cell Biol. 39, 1987-1994 (2007).
    • (2007) Int. J. Biochem. Cell Biol , vol.39 , pp. 1987-1994
    • Kass, L.1    Erler, J.T.2    Dembo, M.3    Weaver, V.M.4
  • 14
  • 15
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • Gumbiner, B. M. Regulation of cadherin-mediated adhesion in morphogenesis. Nature Rev. Mol. Cell Biol. 6, 622-634 (2005).
    • (2005) Nature Rev. Mol. Cell Biol , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 16
    • 0035950105 scopus 로고    scopus 로고
    • Morphogen gradient interpretation
    • Gurdon, J. B. & Bourillot, P. Y. Morphogen gradient interpretation. Nature 413, 797-803 (2001).
    • (2001) Nature , vol.413 , pp. 797-803
    • Gurdon, J.B.1    Bourillot, P.Y.2
  • 17
  • 18
    • 33947327064 scopus 로고    scopus 로고
    • Tissue/planar cell polarity in vertebrates: New insights and new questions
    • Wang, Y. & Nathans, J. Tissue/planar cell polarity in vertebrates: new insights and new questions. Development 134, 647-658 (2007).
    • (2007) Development , vol.134 , pp. 647-658
    • Wang, Y.1    Nathans, J.2
  • 19
    • 34250019911 scopus 로고    scopus 로고
    • Planar polarity and tissue morphogenesis
    • Zallen, J. A. Planar polarity and tissue morphogenesis. Cell 129, 1051-1063 (2007).
    • (2007) Cell , vol.129 , pp. 1051-1063
    • Zallen, J.A.1
  • 20
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • Yang, J. & Weinberg, R. A. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell 14, 818-829 (2008).
    • (2008) Dev. Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 21
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery, J. P. & Sleeman, J. P. Complex networks orchestrate epithelial-mesenchymal transitions. Nature Rev. Mol. Cell Biol. 7, 131-142 (2006).
    • (2006) Nature Rev. Mol. Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 22
    • 0036303782 scopus 로고    scopus 로고
    • Coordinating early kidney development: Lessons from gene targeting
    • Vainio, S. & Lin, Y. Coordinating early kidney development: lessons from gene targeting. Nature Rev. Genet. 3, 533-543 (2002).
    • (2002) Nature Rev. Genet , vol.3 , pp. 533-543
    • Vainio, S.1    Lin, Y.2
  • 23
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani, S. A. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715 (2008).
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 24
    • 25444443688 scopus 로고    scopus 로고
    • Modelling glandular epithelial cancers in three-dimensional cultures
    • Debnath, J. & Brugge, J. S. Modelling glandular epithelial cancers in three-dimensional cultures. Nature Rev. Cancer 5, 675-688 (2005).
    • (2005) Nature Rev. Cancer , vol.5 , pp. 675-688
    • Debnath, J.1    Brugge, J.S.2
  • 25
    • 34248209601 scopus 로고    scopus 로고
    • Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis
    • Leroy, P. & Mostov, K. E. Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis. Mol. Biol. Cell 18, 1943-1952 (2007).
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1943-1952
    • Leroy, P.1    Mostov, K.E.2
  • 26
    • 4344708377 scopus 로고    scopus 로고
    • ERK and MMPs sequentially regulate distinct stages of epithelial tubule development
    • References 25 and 26 describe a pEMT event during morphogenesis and its molecular regulation
    • O'Brien, L. E. et al. ERK and MMPs sequentially regulate distinct stages of epithelial tubule development. Dev. Cell 7, 21-32 (2004). References 25 and 26 describe a pEMT event during morphogenesis and its molecular regulation.
    • (2004) Dev. Cell , vol.7 , pp. 21-32
    • O'Brien, L.E.1
  • 27
    • 24144445140 scopus 로고    scopus 로고
    • Regulatory mechanisms required for DE-cadherin function in cell migration and other types of adhesion
    • Pacquelet, A. & Rorth, P. Regulatory mechanisms required for DE-cadherin function in cell migration and other types of adhesion. J. Cell Biol. 170, 803-812 (2005).
    • (2005) J. Cell Biol , vol.170 , pp. 803-812
    • Pacquelet, A.1    Rorth, P.2
  • 28
    • 34249328426 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of border cell migration analyzed using time-lapse live-cell imaging
    • Prasad, M. & Montell, D. J. Cellular and molecular mechanisms of border cell migration analyzed using time-lapse live-cell imaging. Dev. Cell 12, 997-1005 (2007).
    • (2007) Dev. Cell , vol.12 , pp. 997-1005
    • Prasad, M.1    Montell, D.J.2
  • 29
    • 34249289041 scopus 로고    scopus 로고
    • Peinado, H., Olmeda, D. & Cano, A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nature Rev. Cancer 7, 415-428 (2007).
    • Peinado, H., Olmeda, D. & Cano, A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nature Rev. Cancer 7, 415-428 (2007).
  • 30
    • 35548974844 scopus 로고    scopus 로고
    • The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
    • Aigner, K. et al. The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene 26, 6979-6988 (2007).
    • (2007) Oncogene , vol.26 , pp. 6979-6988
    • Aigner, K.1
  • 31
    • 45549105086 scopus 로고    scopus 로고
    • The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes
    • References 30 and 31 demonstrate that direct repression of polarity complexes by ZEB and Snail factors modulates EMT
    • Whiteman, E. L., Liu, C. J., Fearon, E. R. & Margolis, B. The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes. Oncogene 27, 3875-3879 (2008). References 30 and 31 demonstrate that direct repression of polarity complexes by ZEB and Snail factors modulates EMT.
    • (2008) Oncogene , vol.27 , pp. 3875-3879
    • Whiteman, E.L.1    Liu, C.J.2    Fearon, E.R.3    Margolis, B.4
  • 32
    • 22244432840 scopus 로고    scopus 로고
    • The transcription factor Snail induces tumor cell invasion through modulation of the epithelial cell differentiation program
    • De Craene, B. et al. The transcription factor Snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer Res. 65, 6237-6244 (2005).
    • (2005) Cancer Res , vol.65 , pp. 6237-6244
    • De Craene, B.1
  • 33
    • 33748116186 scopus 로고    scopus 로고
    • A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
    • Spaderna, S. et al. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology 131, 830-840 (2006).
    • (2006) Gastroenterology , vol.131 , pp. 830-840
    • Spaderna, S.1
  • 34
    • 41149112564 scopus 로고    scopus 로고
    • A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition
    • Beltran, M. et al. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. Genes Dev. 22, 756-769 (2008).
    • (2008) Genes Dev , vol.22 , pp. 756-769
    • Beltran, M.1
  • 35
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory, P. A. et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nature Cell Biol. 10, 593-601 (2008).
    • (2008) Nature Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1
  • 36
    • 44649163918 scopus 로고    scopus 로고
    • Burk, U. et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 9, 582-589 (2008). References 35 and 36 reveal mutual antagonism between miRNAs and ZEB1 in controlling epithelial differentiation.
    • Burk, U. et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 9, 582-589 (2008). References 35 and 36 reveal mutual antagonism between miRNAs and ZEB1 in controlling epithelial differentiation.
  • 37
    • 0034854201 scopus 로고    scopus 로고
    • Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly
    • O'Brien, L. E. et al. Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly. Nature Cell Biol. 3, 831-838 (2001).
    • (2001) Nature Cell Biol , vol.3 , pp. 831-838
    • O'Brien, L.E.1
  • 38
    • 51049124493 scopus 로고    scopus 로고
    • Involvement of RhoA, ROCKI and myosin II in inverted orientation of epithelial polarity
    • 923-929
    • Yu, W. et al. Involvement of RhoA, ROCKI and myosin II in inverted orientation of epithelial polarity. EMBO Rep. 9, 923-929 (2008).
    • (2008) EMBO Rep , vol.9
    • Yu, W.1
  • 39
    • 34848869140 scopus 로고    scopus 로고
    • The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity
    • Pegtel, D. M. et al. The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity. Curr. Biol. 17, 1623-1634 (2007).
    • (2007) Curr. Biol , vol.17 , pp. 1623-1634
    • Pegtel, D.M.1
  • 41
    • 4944259722 scopus 로고    scopus 로고
    • Reversal of glandular polarity in the lymphovascular compartment of breast cancer
    • Adams, S. A., Smith, M. E., Cowley, G. P. & Carr, L. A. Reversal of glandular polarity in the lymphovascular compartment of breast cancer. J. Clin. Pathol. 57, 1114-1117 (2004).
    • (2004) J. Clin. Pathol , vol.57 , pp. 1114-1117
    • Adams, S.A.1    Smith, M.E.2    Cowley, G.P.3    Carr, L.A.4
  • 42
    • 36749044792 scopus 로고    scopus 로고
    • EGFR and β1 integrins utilize different signaling pathways to activate Akt
    • Velling, T., Stefansson, A. & Johansson, S. EGFR and β1 integrins utilize different signaling pathways to activate Akt. Exp. Cell Res. 314, 309-316 (2008).
    • (2008) Exp. Cell Res , vol.314 , pp. 309-316
    • Velling, T.1    Stefansson, A.2    Johansson, S.3
  • 43
    • 41649101295 scopus 로고    scopus 로고
    • 3 synthesis promotes the development and survival of early mammalian embryos. Development 135, 425-429 (2008).
    • 3 synthesis promotes the development and survival of early mammalian embryos. Development 135, 425-429 (2008).
  • 44
    • 0037155159 scopus 로고    scopus 로고
    • Kovacs, E. M., Ali, R. G., McCormack, A. J. & Yap, A. S. E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts. J. Biol. Chem. 277, 6708-6718 (2002).
    • Kovacs, E. M., Ali, R. G., McCormack, A. J. & Yap, A. S. E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts. J. Biol. Chem. 277, 6708-6718 (2002).
  • 45
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe, A. B. & Hall, A. Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21, 247-269 (2005).
    • (2005) Annu. Rev. Cell Dev. Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 46
    • 33846270032 scopus 로고    scopus 로고
    • PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
    • Shows, together with reference 70, hollowing as a mechanism for de novo lumen formation. Also details a role for PtdInsP and polarity complexes in lumen formation
    • Martin-Belmonte, F. et al. PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell 128, 383-397 (2007). Shows, together with reference 70, hollowing as a mechanism for de novo lumen formation. Also details a role for PtdInsP and polarity complexes in lumen formation.
    • (2007) Cell , vol.128 , pp. 383-397
    • Martin-Belmonte, F.1
  • 47
    • 41449087759 scopus 로고    scopus 로고
    • Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis
    • Martin-Belmonte, F. et al. Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr. Biol. 18, 507-513 (2008).
    • (2008) Curr. Biol , vol.18 , pp. 507-513
    • Martin-Belmonte, F.1
  • 48
    • 35349019235 scopus 로고    scopus 로고
    • Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development
    • Wu, X. et al. Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development. Dev. Dyn. 236, 2767-2778 (2007).
    • (2007) Dev. Dyn , vol.236 , pp. 2767-2778
    • Wu, X.1
  • 49
    • 0042354714 scopus 로고    scopus 로고
    • Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
    • Xu, J. et al. Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 114, 201-214 (2003).
    • (2003) Cell , vol.114 , pp. 201-214
    • Xu, J.1
  • 50
    • 34547191723 scopus 로고    scopus 로고
    • Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis
    • Lecuit, T. & Lenne, P. F. Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis. Nature Rev. Mol. Cell Biol. 8, 633-644 (2007).
    • (2007) Nature Rev. Mol. Cell Biol , vol.8 , pp. 633-644
    • Lecuit, T.1    Lenne, P.F.2
  • 51
    • 33644865751 scopus 로고    scopus 로고
    • Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism
    • Wong, K., Pertz, O., Hahn, K. & Bourne, H. Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism. Proc. Natl Acad. Sci. USA 103, 3639-3644 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 3639-3644
    • Wong, K.1    Pertz, O.2    Hahn, K.3    Bourne, H.4
  • 52
    • 0037416217 scopus 로고    scopus 로고
    • Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
    • Garrard, S. M. et al. Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6. EMBO J. 22, 1125-1133 (2003).
    • (2003) EMBO J , vol.22 , pp. 1125-1133
    • Garrard, S.M.1
  • 53
    • 46449101973 scopus 로고    scopus 로고
    • Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts
    • Anderson, D. C., Gill, J. S., Cinalli, R. M. & Nance, J. Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts. Science 320, 1771-1774 (2008).
    • (2008) Science , vol.320 , pp. 1771-1774
    • Anderson, D.C.1    Gill, J.S.2    Cinalli, R.M.3    Nance, J.4
  • 54
    • 0031443277 scopus 로고    scopus 로고
    • The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation
    • Barrett, K., Leptin, M. & Settleman, J. The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell 91, 905-915 (1997).
    • (1997) Cell , vol.91 , pp. 905-915
    • Barrett, K.1    Leptin, M.2    Settleman, J.3
  • 55
    • 0035071323 scopus 로고    scopus 로고
    • p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
    • Brouns, M. R., Matheson, S. F. & Settleman, J. p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nature Cell Biol. 3, 361-367 (2001).
    • (2001) Nature Cell Biol , vol.3 , pp. 361-367
    • Brouns, M.R.1    Matheson, S.F.2    Settleman, J.3
  • 56
    • 0031965218 scopus 로고    scopus 로고
    • DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila
    • Hacker, U. & Perrimon, N. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes Dev. 12, 274-284 (1998).
    • (1998) Genes Dev , vol.12 , pp. 274-284
    • Hacker, U.1    Perrimon, N.2
  • 57
    • 0346403360 scopus 로고    scopus 로고
    • Shroom induces apical constriction and is required for hingepoint formation during neural tube closure
    • Haigo, S. L., Hildebrand, J. D., Harland, R. M. & Wallingford, J. B. Shroom induces apical constriction and is required for hingepoint formation during neural tube closure. Curr. Biol. 13, 2125-2137 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 2125-2137
    • Haigo, S.L.1    Hildebrand, J.D.2    Harland, R.M.3    Wallingford, J.B.4
  • 58
    • 33846618654 scopus 로고    scopus 로고
    • Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2
    • Kolsch, V., Seher, T., Fernandez-Ballester, G. J., Serrano, L. & Leptin, M. Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science 315, 384-386 (2007).
    • (2007) Science , vol.315 , pp. 384-386
    • Kolsch, V.1    Seher, T.2    Fernandez-Ballester, G.J.3    Serrano, L.4    Leptin, M.5
  • 59
    • 6944220167 scopus 로고    scopus 로고
    • A Rho GTPase signaling pathway is used reiteratively in epithelial folding and potentially selects the outcome of Rho activation
    • References 54-59 collectively define crucial roles for apical activation and basal inactivation of RhoA by GEFs and GAPs, respectively, in tissue morphogenesis
    • Nikolaidou, K. K. & Barrett, K. A Rho GTPase signaling pathway is used reiteratively in epithelial folding and potentially selects the outcome of Rho activation. Curr. Biol. 14, 1822-1826 (2004). References 54-59 collectively define crucial roles for apical activation and basal inactivation of RhoA by GEFs and GAPs, respectively, in tissue morphogenesis.
    • (2004) Curr. Biol , vol.14 , pp. 1822-1826
    • Nikolaidou, K.K.1    Barrett, K.2
  • 60
    • 38849119148 scopus 로고    scopus 로고
    • The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase
    • Zhang, H. & Macara, I. G. The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev. Cell 14, 216-226 (2008).
    • (2008) Dev. Cell , vol.14 , pp. 216-226
    • Zhang, H.1    Macara, I.G.2
  • 61
    • 38849122774 scopus 로고    scopus 로고
    • Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation
    • Nakayama, M. et al. Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation. Dev. Cell 14, 205-215 (2008).
    • (2008) Dev. Cell , vol.14 , pp. 205-215
    • Nakayama, M.1
  • 62
    • 34548295310 scopus 로고    scopus 로고
    • Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic
    • Balklava, Z., Pant, S., Fares, H. & Grant, B. D. Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nature Cell Biol. 9, 1066-1073 (2007).
    • (2007) Nature Cell Biol , vol.9 , pp. 1066-1073
    • Balklava, Z.1    Pant, S.2    Fares, H.3    Grant, B.D.4
  • 63
    • 0037428084 scopus 로고    scopus 로고
    • Tube morphogenesis: Making and shaping biological tubes
    • Lubarsky, B. & Krasnow, M. A. Tube morphogenesis: making and shaping biological tubes. Cell 112, 19-28 (2003).
    • (2003) Cell , vol.112 , pp. 19-28
    • Lubarsky, B.1    Krasnow, M.A.2
  • 64
    • 0036633647 scopus 로고    scopus 로고
    • Organogenesis: Molecular mechanisms of tubulogenesis
    • Hogan, B. L. & Kolodziej, P. A. Organogenesis: molecular mechanisms of tubulogenesis. Nature Rev. Genet. 3, 513-523 (2002).
    • (2002) Nature Rev. Genet , vol.3 , pp. 513-523
    • Hogan, B.L.1    Kolodziej, P.A.2
  • 65
    • 0037020196 scopus 로고    scopus 로고
    • The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
    • Debnath, J. et al. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 111, 29-40 (2002).
    • (2002) Cell , vol.111 , pp. 29-40
    • Debnath, J.1
  • 66
    • 33846630384 scopus 로고    scopus 로고
    • Mailleux, A. A. et al. BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Dev. Cell 12, 221-234 (2007). References 47, 65 and 66 detail cavitation as a mechanism for lumen formation in 3D culture and in vivo.
    • Mailleux, A. A. et al. BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Dev. Cell 12, 221-234 (2007). References 47, 65 and 66 detail cavitation as a mechanism for lumen formation in 3D culture and in vivo.
  • 67
    • 4043170088 scopus 로고    scopus 로고
    • Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors
    • Bilder, D. Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 18, 1909-1925 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1909-1925
    • Bilder, D.1
  • 68
    • 33750505436 scopus 로고    scopus 로고
    • Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control
    • Aranda, V. et al. Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nature Cell Biol. 8, 1235-1245 (2006).
    • (2006) Nature Cell Biol , vol.8 , pp. 1235-1245
    • Aranda, V.1
  • 69
    • 0029967619 scopus 로고    scopus 로고
    • An α2β1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix
    • Davis, G. E. & Camarillo, C. W. An α2β1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix. Exp. Cell Res. 224, 39-51 (1996).
    • (1996) Exp. Cell Res , vol.224 , pp. 39-51
    • Davis, G.E.1    Camarillo, C.W.2
  • 70
    • 33747139066 scopus 로고    scopus 로고
    • Endothelial tubes assemble from intracellular vacuoles in vivo
    • Kamei, M. et al. Endothelial tubes assemble from intracellular vacuoles in vivo. Nature 442, 453-456 (2006).
    • (2006) Nature , vol.442 , pp. 453-456
    • Kamei, M.1
  • 71
    • 41149157843 scopus 로고    scopus 로고
    • Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo
    • Blum, Y. et al. Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo. Dev. Biol. 316, 312-322 (2008).
    • (2008) Dev. Biol , vol.316 , pp. 312-322
    • Blum, Y.1
  • 72
    • 0035797907 scopus 로고    scopus 로고
    • Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis
    • Horne-Badovinac, S. et al. Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis. Curr. Biol. 11, 1492-1502 (2001).
    • (2001) Curr. Biol , vol.11 , pp. 1492-1502
    • Horne-Badovinac, S.1
  • 73
    • 34547811037 scopus 로고    scopus 로고
    • Polarity proteins PAR6 and aPKC regulate cell death through GSK-3β in 3D epithelial morphogenesis
    • Kim, M., Datta, A., Brakeman, P., Yu, W. & Mostov, K. E. Polarity proteins PAR6 and aPKC regulate cell death through GSK-3β in 3D epithelial morphogenesis. J. Cell Sci. 120, 2309-2317 (2007).
    • (2007) J. Cell Sci , vol.120 , pp. 2309-2317
    • Kim, M.1    Datta, A.2    Brakeman, P.3    Yu, W.4    Mostov, K.E.5
  • 74
    • 48249106224 scopus 로고    scopus 로고
    • Genetic control of cell morphogenesis during Drosophila melanogaster cardiac tube formation
    • Medioni, C., Astier, M., Zmojdzian, M., Jagla, K. & Sémériva, M. Genetic control of cell morphogenesis during Drosophila melanogaster cardiac tube formation. J. Cell Biol. 182, 249-261 (2008).
    • (2008) J. Cell Biol , vol.182 , pp. 249-261
    • Medioni, C.1    Astier, M.2    Zmojdzian, M.3    Jagla, K.4    Sémériva, M.5
  • 75
    • 48249101541 scopus 로고    scopus 로고
    • Repulsion by Slit and Roundabout prevents Shotgun/E-cadherin-mediated cell adhesion during Drosophila heart tube lumen formation
    • Santiago-Martínez, E., Saplop, N. H., Patel, R. & Kramer, S. G. Repulsion by Slit and Roundabout prevents Shotgun/E-cadherin-mediated cell adhesion during Drosophila heart tube lumen formation. J. Cell Biol. 182, 241-248 (2008).
    • (2008) J. Cell Biol , vol.182 , pp. 241-248
    • Santiago-Martínez, E.1    Saplop, N.H.2    Patel, R.3    Kramer, S.G.4
  • 76
    • 13844289424 scopus 로고    scopus 로고
    • Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells
    • Meder, D., Shevchenko, A., Simons, K. & Fullekrug, J. Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. J. Cell Biol. 168, 303-313 (2005).
    • (2005) J. Cell Biol , vol.168 , pp. 303-313
    • Meder, D.1    Shevchenko, A.2    Simons, K.3    Fullekrug, J.4
  • 77
    • 44849091512 scopus 로고    scopus 로고
    • The branching programme of mouse lung development
    • Metzger, R. J., Klein, O. D., Martin, G. R. & Krasnow, M. A. The branching programme of mouse lung development. Nature 453, 745-750 (2008).
    • (2008) Nature , vol.453 , pp. 745-750
    • Metzger, R.J.1    Klein, O.D.2    Martin, G.R.3    Krasnow, M.A.4
  • 79
    • 0346258173 scopus 로고    scopus 로고
    • Distinct sites in E-cadherin regulate different steps in Drosophila tracheal tube fusion
    • Lee, M., Lee, S., Zadeh, A. D. & Kolodziej, P. A. Distinct sites in E-cadherin regulate different steps in Drosophila tracheal tube fusion. Development 130, 5989-5999 (2003).
    • (2003) Development , vol.130 , pp. 5989-5999
    • Lee, M.1    Lee, S.2    Zadeh, A.D.3    Kolodziej, P.A.4
  • 80
    • 48649098952 scopus 로고    scopus 로고
    • Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea
    • Shaye, D. D., Casanova, J. & Llimargas, M. Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea. Nature Cell Biol. 10, 964-970 (2008).
    • (2008) Nature Cell Biol , vol.10 , pp. 964-970
    • Shaye, D.D.1    Casanova, J.2    Llimargas, M.3
  • 81
    • 47649124451 scopus 로고    scopus 로고
    • Tracheal branching morphogenesis in Drosophila: New insights into cell behaviour and organ architecture
    • Affolter, M. & Caussinus, E. Tracheal branching morphogenesis in Drosophila: new insights into cell behaviour and organ architecture. Development 135, 2055-2064 (2008).
    • (2008) Development , vol.135 , pp. 2055-2064
    • Affolter, M.1    Caussinus, E.2
  • 82
    • 14644397215 scopus 로고    scopus 로고
    • Papillote and Piopio: Drosophila ZP-domain proteins required for cell adhesion to the apical extracellular matrix and microtubule organization
    • Bokel, C., Prokop, A. & Brown, N. H. Papillote and Piopio: Drosophila ZP-domain proteins required for cell adhesion to the apical extracellular matrix and microtubule organization. J. Cell Sci. 118, 633-642 (2005).
    • (2005) J. Cell Sci , vol.118 , pp. 633-642
    • Bokel, C.1    Prokop, A.2    Brown, N.H.3
  • 83
    • 0141505122 scopus 로고    scopus 로고
    • Jazwinska, A., Ribeiro, C. & Affolter, M. Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein. Nature Cell Biol. 5, 895-901 (2003). References 82, 83, 94 and 95 describe roles for different types of apical ECM in the formation of luminal structures in D. melanogaster tissues.
    • Jazwinska, A., Ribeiro, C. & Affolter, M. Epithelial tube morphogenesis during Drosophila tracheal development requires Piopio, a luminal ZP protein. Nature Cell Biol. 5, 895-901 (2003). References 82, 83, 94 and 95 describe roles for different types of apical ECM in the formation of luminal structures in D. melanogaster tissues.
  • 84
    • 41649121862 scopus 로고    scopus 로고
    • Ewald, A. J., Brenot, A., Duong, M., Chan, B. S. & Werb, Z. Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev. Cell 14, 570-581 (2008). Describes in vitro branching of mammary organoids through a multilayered epithelial state.
    • Ewald, A. J., Brenot, A., Duong, M., Chan, B. S. & Werb, Z. Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev. Cell 14, 570-581 (2008). Describes in vitro branching of mammary organoids through a multilayered epithelial state.
  • 85
    • 0142106807 scopus 로고    scopus 로고
    • Role of polycystins in renal tubulogenesis
    • Boletta, A. & Germino, G. G. Role of polycystins in renal tubulogenesis. Trends Cell Biol. 13, 484-492 (2003).
    • (2003) Trends Cell Biol , vol.13 , pp. 484-492
    • Boletta, A.1    Germino, G.G.2
  • 87
    • 34547576923 scopus 로고    scopus 로고
    • +-ATPase, septate junctions and TJs in lumen formation.
    • +-ATPase, septate junctions and TJs in lumen formation.
  • 88
    • 0027938487 scopus 로고
    • Thyroid epithelial morphogenesis in vitro: A role for bumetanide-sensitive Cl-secretion during follicular lumen development
    • Yap, A. S., Stevenson, B. R., Armstrong, J. W., Keast, J. R. & Manley, S. W. Thyroid epithelial morphogenesis in vitro: a role for bumetanide-sensitive Cl-secretion during follicular lumen development. Exp. Cell Res. 213, 319-326 (1994).
    • (1994) Exp. Cell Res , vol.213 , pp. 319-326
    • Yap, A.S.1    Stevenson, B.R.2    Armstrong, J.W.3    Keast, J.R.4    Manley, S.W.5
  • 89
    • 48149087107 scopus 로고    scopus 로고
    • Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease
    • Yang, B., Sonawane, N. D., Zhao, D., Somlo, S. & Verkman, A. S. Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease. J. Am. Soc. Nephrol. 19, 1300-1310 (2008).
    • (2008) J. Am. Soc. Nephrol , vol.19 , pp. 1300-1310
    • Yang, B.1    Sonawane, N.D.2    Zhao, D.3    Somlo, S.4    Verkman, A.S.5
  • 90
    • 33846471264 scopus 로고    scopus 로고
    • A pumpin-dependent function of the Na, K-ATPase is required for epithelial junction function and tracheal tube-size control
    • Paul, S. M., Palladino, M. J. & Beitel, G. J. A pumpin-dependent function of the Na, K-ATPase is required for epithelial junction function and tracheal tube-size control. Development 134, 147-155 (2007).
    • (2007) Development , vol.134 , pp. 147-155
    • Paul, S.M.1    Palladino, M.J.2    Beitel, G.J.3
  • 91
    • 1642458089 scopus 로고    scopus 로고
    • Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control
    • Wu, V. M., Schulte, J., Hirschi, A., Tepass, U. & Beitel, G. J. Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control. J. Cell Biol. 164, 313-323 (2004).
    • (2004) J. Cell Biol , vol.164 , pp. 313-323
    • Wu, V.M.1    Schulte, J.2    Hirschi, A.3    Tepass, U.4    Beitel, G.J.5
  • 93
    • 34547530484 scopus 로고    scopus 로고
    • Sequential pulses of apical epithelial secretion and endocytosis drive airway maturation in Drosophila
    • References 92 and 93 characterize crucial roles for apical secretion and endocytosis in lumen expansion and morphogenesis
    • Tsarouhas, V. et al. Sequential pulses of apical epithelial secretion and endocytosis drive airway maturation in Drosophila. Dev. Cell 13, 214-225 (2007). References 92 and 93 characterize crucial roles for apical secretion and endocytosis in lumen expansion and morphogenesis.
    • (2007) Dev. Cell , vol.13 , pp. 214-225
    • Tsarouhas, V.1
  • 94
    • 30944451526 scopus 로고    scopus 로고
    • Tubulogenesis: An inside job
    • Swanson, L. E. & Beitel, G. J. Tubulogenesis: an inside job. Curr. Biol. 16, R51-R53 (2006).
    • (2006) Curr. Biol , vol.16
    • Swanson, L.E.1    Beitel, G.J.2
  • 95
    • 33748948080 scopus 로고    scopus 로고
    • The agrin/perlecan-related protein eyes shut is essential for epithelial lumen formation in the Drosophila retina
    • Husain, N. et al. The agrin/perlecan-related protein eyes shut is essential for epithelial lumen formation in the Drosophila retina. Dev. Cell 11, 483-493 (2006).
    • (2006) Dev. Cell , vol.11 , pp. 483-493
    • Husain, N.1
  • 96
    • 48949115131 scopus 로고    scopus 로고
    • Ribbon modulates apical membrane during tube elongation through Crumbs and Moesin
    • Kerman, B. E., Cheshire, A. M., Myat, M. M. & Andrew, D. J. Ribbon modulates apical membrane during tube elongation through Crumbs and Moesin. Dev. Biol. 320, 278-288 (2008).
    • (2008) Dev. Biol , vol.320 , pp. 278-288
    • Kerman, B.E.1    Cheshire, A.M.2    Myat, M.M.3    Andrew, D.J.4
  • 97
    • 0037074004 scopus 로고    scopus 로고
    • Epithelial tube morphology is determined by the polarized growth and delivery of apical membrane
    • Myat, M. M. & Andrew, D. J. Epithelial tube morphology is determined by the polarized growth and delivery of apical membrane. Cell 111, 879-891 (2002).
    • (2002) Cell , vol.111 , pp. 879-891
    • Myat, M.M.1    Andrew, D.J.2
  • 98
    • 34249100238 scopus 로고    scopus 로고
    • Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptors
    • Li, B. X., Satoh, A. K. & Ready, D. F. Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptors. J. Cell Biol. 177, 659-669 (2007).
    • (2007) J. Cell Biol , vol.177 , pp. 659-669
    • Li, B.X.1    Satoh, A.K.2    Ready, D.F.3
  • 99
    • 54549122971 scopus 로고    scopus 로고
    • American Cancer Society, American Cancer Society, Atlanta
    • American Cancer Society. Cancer Facts & Figs 2008 (American Cancer Society, Atlanta, 2008).
    • (2008) Cancer Facts & Figs 2008
  • 100
    • 44449135987 scopus 로고    scopus 로고
    • Cell polarity and cancer-cell and tissue polarity as a non-canonical tumor suppressor
    • Lee, M. & Vasioukhin, V. Cell polarity and cancer-cell and tissue polarity as a non-canonical tumor suppressor. J. Cell Sci. 121, 1141-1150 (2008).
    • (2008) J. Cell Sci , vol.121 , pp. 1141-1150
    • Lee, M.1    Vasioukhin, V.2
  • 102
    • 9544231691 scopus 로고    scopus 로고
    • Epidemiology of acute renal failure: A prospective, multicenter, community-based study. Madrid acute renal failure study group
    • Liano, F. & Pascual, J. Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid acute renal failure study group. Kidney Int. 50, 811-818 (1996).
    • (1996) Kidney Int , vol.50 , pp. 811-818
    • Liano, F.1    Pascual, J.2
  • 103
    • 26244446442 scopus 로고    scopus 로고
    • Acute lung injury and the acute respiratory distress syndrome: Four decades of inquiry into pathogenesis and rational management
    • Matthay, M. A. & Zimmerman, G. A. Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am. J. Respir. Cell Mol. Biol. 33, 319-327 (2005).
    • (2005) Am. J. Respir. Cell Mol. Biol , vol.33 , pp. 319-327
    • Matthay, M.A.1    Zimmerman, G.A.2
  • 104
    • 39749172401 scopus 로고    scopus 로고
    • Intrinsic epithelial cells repair the kidney after injury
    • Humphreys, B. D. et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 2, 284-291 (2008).
    • (2008) Cell Stem Cell , vol.2 , pp. 284-291
    • Humphreys, B.D.1
  • 105
    • 0018142634 scopus 로고
    • Ischemic damage and repair in the rat proximal tubule: Differences among the S1, S2, and S3 segments
    • Venkatachalam, M. A., Bernard, D. B., Donohoe, J. F. & Levinsky, N. G. Ischemic damage and repair in the rat proximal tubule: differences among the S1, S2, and S3 segments. Kidney Int. 14, 31-49 (1978).
    • (1978) Kidney Int , vol.14 , pp. 31-49
    • Venkatachalam, M.A.1    Bernard, D.B.2    Donohoe, J.F.3    Levinsky, N.G.4
  • 106
    • 34249052234 scopus 로고    scopus 로고
    • Bottinger, E. P. TGF-β in renal injury and disease. Semin. Nephrol. 27, 309-320 (2007).
    • Bottinger, E. P. TGF-β in renal injury and disease. Semin. Nephrol. 27, 309-320 (2007).
  • 107
    • 0344413422 scopus 로고    scopus 로고
    • Apicobasal polarization: Epithelial form and function
    • Gibson, M. C. & Perrimon, N. Apicobasal polarization: epithelial form and function. Curr. Opin. Cell Biol. 15, 747-752 (2003).
    • (2003) Curr. Opin. Cell Biol , vol.15 , pp. 747-752
    • Gibson, M.C.1    Perrimon, N.2
  • 108
    • 0037385561 scopus 로고    scopus 로고
    • A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl
    • Plant, P. J. et al. A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nature Cell Biol. 5, 301-308 (2003).
    • (2003) Nature Cell Biol , vol.5 , pp. 301-308
    • Plant, P.J.1
  • 109
    • 0000941724 scopus 로고
    • Switches, thresholds and ultrasensitivity
    • Koshland, D. E. Switches, thresholds and ultrasensitivity. Trends Biochem. Sci. 12, 225-229 (1987).
    • (1987) Trends Biochem. Sci , vol.12 , pp. 225-229
    • Koshland, D.E.1
  • 110
    • 48649107982 scopus 로고    scopus 로고
    • EphrinB1 controls cell-cell junctions through the Par polarity complex
    • Lee, H. S., Nishanian, T. G., Mood, K., Bong, Y. S. & Daar, I. O. EphrinB1 controls cell-cell junctions through the Par polarity complex. Nature Cell Biol. 10, 979-986 (2008).
    • (2008) Nature Cell Biol , vol.10 , pp. 979-986
    • Lee, H.S.1    Nishanian, T.G.2    Mood, K.3    Bong, Y.S.4    Daar, I.O.5
  • 111
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFβ receptors controls epithelial cell plasticity
    • Ozdamar, B. et al. Regulation of the polarity protein Par6 by TGFβ receptors controls epithelial cell plasticity. Science 307, 1603-1609 (2005).
    • (2005) Science , vol.307 , pp. 1603-1609
    • Ozdamar, B.1
  • 112
    • 33751347857 scopus 로고    scopus 로고
    • The Scribble and Par complexes in polarity and migration: Friends or foes?
    • Humbert, P. O., Dow, L. E. & Russell, S. M. The Scribble and Par complexes in polarity and migration: friends or foes? Trends Cell Biol. 16, 622-630 (2006).
    • (2006) Trends Cell Biol , vol.16 , pp. 622-630
    • Humbert, P.O.1    Dow, L.E.2    Russell, S.M.3
  • 113
    • 33749836234 scopus 로고    scopus 로고
    • Phosphoinositides in cell regulation and membrane dynamics
    • Di Paolo, G. & De Camilli, P. Phosphoinositides in cell regulation and membrane dynamics. Nature 443, 651-657 (2006).
    • (2006) Nature , vol.443 , pp. 651-657
    • Di Paolo, G.1    De Camilli, P.2
  • 114
    • 0037415640 scopus 로고    scopus 로고
    • 3 and polarity during neutrophil chemotaxis. J. Cell Biol. 160, 375-385 (2003).
    • 3 and polarity during neutrophil chemotaxis. J. Cell Biol. 160, 375-385 (2003).
  • 115
    • 30944433152 scopus 로고    scopus 로고
    • 3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells. Curr. Biol. 16, 140-149 (2006).
    • 3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells. Curr. Biol. 16, 140-149 (2006).
  • 116
    • 0037328574 scopus 로고    scopus 로고
    • Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures
    • Yu, W. et al. Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Mol. Biol. Cell 14, 748-763 (2003).
    • (2003) Mol. Biol. Cell , vol.14 , pp. 748-763
    • Yu, W.1
  • 117
    • 33746706949 scopus 로고    scopus 로고
    • Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz
    • Pilot, F., Philippe, J. M., Lemmers, C. & Lecuit, T. Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz. Nature 442, 580-584 (2006).
    • (2006) Nature , vol.442 , pp. 580-584
    • Pilot, F.1    Philippe, J.M.2    Lemmers, C.3    Lecuit, T.4
  • 118
    • 17744386543 scopus 로고    scopus 로고
    • Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling
    • von Stein, W., Ramrath, A., Grimm, A., Muller-Borg, M. & Wodarz, A. Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling. Development 132, 1675-1686 (2005).
    • (2005) Development , vol.132 , pp. 1675-1686
    • von Stein, W.1    Ramrath, A.2    Grimm, A.3    Muller-Borg, M.4    Wodarz, A.5
  • 119
    • 53149149836 scopus 로고    scopus 로고
    • PAR-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment
    • References 118 and 119 demonstrate the direct interaction of PAR-3 with PTEN, revealing regulation of PtdInsP asymmetry by the PAR complex
    • Feng, W., Wu, H., Chan, L. N. & Zhang, M. PAR-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment. J. Biol. Chem. 283, 23440-23449 (2008). References 118 and 119 demonstrate the direct interaction of PAR-3 with PTEN, revealing regulation of PtdInsP asymmetry by the PAR complex.
    • (2008) J. Biol. Chem , vol.283 , pp. 23440-23449
    • Feng, W.1    Wu, H.2    Chan, L.N.3    Zhang, M.4
  • 120
    • 39549108299 scopus 로고    scopus 로고
    • 3 to the basal region. Biochem. Biophys. Res. Commun. 368, 249-255 (2008).
    • 3 to the basal region. Biochem. Biophys. Res. Commun. 368, 249-255 (2008).
  • 121
    • 33748199154 scopus 로고    scopus 로고
    • Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells
    • Gassama-Diagne, A. et al. Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nature Cell Biol. 8, 963-970 (2006).
    • (2006) Nature Cell Biol , vol.8 , pp. 963-970
    • Gassama-Diagne, A.1
  • 122
    • 34247119640 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane
    • Kierbel, A. et al. Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane. J. Cell Biol. 177, 21-27 (2007).
    • (2007) J. Cell Biol , vol.177 , pp. 21-27
    • Kierbel, A.1
  • 123
    • 35848947444 scopus 로고    scopus 로고
    • 3 are key determinants of epithelial polarity.
    • 3 are key determinants of epithelial polarity.
  • 125
    • 0031408202 scopus 로고    scopus 로고
    • Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells
    • Webber, M. M., Bello, D., Kleinman, H. K. & Hoffman, M. P. Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells. Carcinogenesis 18, 1225-1231 (1997).
    • (1997) Carcinogenesis , vol.18 , pp. 1225-1231
    • Webber, M.M.1    Bello, D.2    Kleinman, H.K.3    Hoffman, M.P.4
  • 126
    • 34248223108 scopus 로고    scopus 로고
    • Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis
    • Yu, W. et al. Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Mol. Biol. Cell 18, 1693-1700 (2007).
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1693-1700
    • Yu, W.1
  • 127
    • 0025825990 scopus 로고
    • Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors
    • Montesano, R., Schaller, G. & Orci, L. Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell 66, 697-711 (1991).
    • (1991) Cell , vol.66 , pp. 697-711
    • Montesano, R.1    Schaller, G.2    Orci, L.3
  • 128
    • 0032387652 scopus 로고    scopus 로고
    • Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis
    • Pollack, A. L., Runyan, R. B. & Mostov, K. E. Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis. Dev. Biol. 204, 64-79 (1998).
    • (1998) Dev. Biol , vol.204 , pp. 64-79
    • Pollack, A.L.1    Runyan, R.B.2    Mostov, K.E.3
  • 129
    • 33750439801 scopus 로고    scopus 로고
    • Simulating properties of in vitro epithelial cell morphogenesis
    • Grant, M. R., Mostov, K. E., Tlsty, T. D. & Hunt, C. A. Simulating properties of in vitro epithelial cell morphogenesis. PLoS Comput. Biol. 2, e129 (2006).
    • (2006) PLoS Comput. Biol , vol.2
    • Grant, M.R.1    Mostov, K.E.2    Tlsty, T.D.3    Hunt, C.A.4
  • 130
    • 0034666356 scopus 로고    scopus 로고
    • Regulation of vesicle trafficking in Madin-Darby canine kidney cells by Rab11a and Rab25
    • Wang, X., Kumar, R., Navarre, J., Casanova, J. E. & Goldenring, J. R. Regulation of vesicle trafficking in Madin-Darby canine kidney cells by Rab11a and Rab25. J. Biol. Chem. 275, 29138-29146 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 29138-29146
    • Wang, X.1    Kumar, R.2    Navarre, J.3    Casanova, J.E.4    Goldenring, J.R.5
  • 131
    • 9144271680 scopus 로고    scopus 로고
    • The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
    • Cheng, K. W. et al. The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. Nature Med. 10, 1251-1256 (2004).
    • (2004) Nature Med , vol.10 , pp. 1251-1256
    • Cheng, K.W.1
  • 132
    • 33748592841 scopus 로고    scopus 로고
    • Junctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains
    • Rehder, D. et al. Junctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains. Exp. Cell Res. 312, 3389-3403 (2006).
    • (2006) Exp. Cell Res , vol.312 , pp. 3389-3403
    • Rehder, D.1
  • 133
    • 44449156338 scopus 로고    scopus 로고
    • Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis
    • Torkko, J. M., Manninen, A., Schuck, S. & Simons, K. Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis. J. Cell Sci. 121, 1193-1203 (2008).
    • (2008) J. Cell Sci , vol.121 , pp. 1193-1203
    • Torkko, J.M.1    Manninen, A.2    Schuck, S.3    Simons, K.4
  • 134
    • 0141891960 scopus 로고    scopus 로고
    • + ATPase is required for septate junction function and epithelial tube-size control in the Drosophila tracheal system
    • + ATPase is required for septate junction function and epithelial tube-size control in the Drosophila tracheal system. Development 130, 4963-4974 (2003).
    • (2003) Development , vol.130 , pp. 4963-4974
    • Paul, S.M.1    Ternet, M.2    Salvaterra, P.M.3    Beitel, G.J.4
  • 135
    • 14744275517 scopus 로고    scopus 로고
    • PATJ regulates tight junction formation and polarity in mammalian epithelial cells
    • Shin, K., Straight, S. & Margolis, B. PATJ regulates tight junction formation and polarity in mammalian epithelial cells. J. Cell Biol. 168, 705-711 (2005).
    • (2005) J. Cell Biol , vol.168 , pp. 705-711
    • Shin, K.1    Straight, S.2    Margolis, B.3
  • 136
    • 0033638380 scopus 로고    scopus 로고
    • Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins
    • Lipschutz, J. H. et al. Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. Mol. Biol. Cell 11, 4259-4275 (2000).
    • (2000) Mol. Biol. Cell , vol.11 , pp. 4259-4275
    • Lipschutz, J.H.1
  • 137
    • 2942626080 scopus 로고    scopus 로고
    • Lumen morphogenesis in C. elegans requires the membrane-cytoskeleton linker ERM-1
    • Gobel, V., Barrett, P. L., Hall, D. H. & Fleming, J. T. Lumen morphogenesis in C. elegans requires the membrane-cytoskeleton linker ERM-1. Dev. Cell 6, 865-873 (2004).
    • (2004) Dev. Cell , vol.6 , pp. 865-873
    • Gobel, V.1    Barrett, P.L.2    Hall, D.H.3    Fleming, J.T.4
  • 138
    • 2942622503 scopus 로고    scopus 로고
    • Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine
    • Saotome, I., Curto, M. & McClatchey, A. I. Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev. Cell 6, 855-864 (2004).
    • (2004) Dev. Cell , vol.6 , pp. 855-864
    • Saotome, I.1    Curto, M.2    McClatchey, A.I.3
  • 139
    • 17444423987 scopus 로고    scopus 로고
    • Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells
    • Beronja, S. et al. Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells. J. Cell Biol. 169, 635-646 (2005).
    • (2005) J. Cell Biol , vol.169 , pp. 635-646
    • Beronja, S.1
  • 140
    • 33747033698 scopus 로고    scopus 로고
    • Nucleotide exchange factor ECT2 regulates epithelial cell polarity
    • Liu, X. F., Ohno, S. & Miki, T. Nucleotide exchange factor ECT2 regulates epithelial cell polarity. Cell Signal 18, 1604-1615 (2006).
    • (2006) Cell Signal , vol.18 , pp. 1604-1615
    • Liu, X.F.1    Ohno, S.2    Miki, T.3
  • 141
    • 35748934517 scopus 로고    scopus 로고
    • The Drosophila Dead end Arf-like3 GTPase controls vesicle trafficking during tracheal fusion cell morphogenesis
    • Jiang, L., Rogers, S. L. & Crews, S. T. The Drosophila Dead end Arf-like3 GTPase controls vesicle trafficking during tracheal fusion cell morphogenesis. Dev. Biol. 311, 487-499 (2007).
    • (2007) Dev. Biol , vol.311 , pp. 487-499
    • Jiang, L.1    Rogers, S.L.2    Crews, S.T.3
  • 142
    • 23944443368 scopus 로고    scopus 로고
    • FAPP2 is involved in the transport of apical cargo in polarized MDCK cells
    • Vieira, O. V., Verkade, P., Manninen, A. & Simons, K. FAPP2 is involved in the transport of apical cargo in polarized MDCK cells. J. Cell Biol. 170, 521-526 (2005).
    • (2005) J. Cell Biol , vol.170 , pp. 521-526
    • Vieira, O.V.1    Verkade, P.2    Manninen, A.3    Simons, K.4
  • 143
    • 34447519003 scopus 로고    scopus 로고
    • The Rab8 GTPase regulates apical protein localization in intestinal cells
    • Sato, T. et al. The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature 448, 366-369 (2007).
    • (2007) Nature , vol.448 , pp. 366-369
    • Sato, T.1
  • 144
    • 54549108389 scopus 로고    scopus 로고
    • Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis
    • Desclozeaux, M. et al. Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis. Am. J. Physiol. Cell Physiol. 295, C545-C556 (2008).
    • (2008) Am. J. Physiol. Cell Physiol , vol.295
    • Desclozeaux, M.1
  • 145
    • 33745273910 scopus 로고    scopus 로고
    • Apical targeting of syntaxin 3 is essential for epithelial cell polarity
    • Sharma, N., Low, S. H., Misra, S., Pallavi, B. & Weimbs, T. Apical targeting of syntaxin 3 is essential for epithelial cell polarity. J. Cell Biol. 173, 937-948 (2006).
    • (2006) J. Cell Biol , vol.173 , pp. 937-948
    • Sharma, N.1    Low, S.H.2    Misra, S.3    Pallavi, B.4    Weimbs, T.5
  • 146
    • 10344222932 scopus 로고    scopus 로고
    • A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans
    • Croce, A. et al. A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans. Nature Cell Biol. 6, 1173-1179 (2004).
    • (2004) Nature Cell Biol , vol.6 , pp. 1173-1179
    • Croce, A.1
  • 147
    • 0035071207 scopus 로고    scopus 로고
    • Mutant cadherin affects epithelial morphogenesis and invasion, but not transformation
    • Troxell, M. L., Loftus, D. J., Nelson, W. J. & Marrs, J. A. Mutant cadherin affects epithelial morphogenesis and invasion, but not transformation. J. Cell Sci. 114, 1237-1246 (2001).
    • (2001) J. Cell Sci , vol.114 , pp. 1237-1246
    • Troxell, M.L.1    Loftus, D.J.2    Nelson, W.J.3    Marrs, J.A.4
  • 148
    • 38349124463 scopus 로고    scopus 로고
    • Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein APG-2
    • Aijaz, S., Sanchez-Heras, E., Balda, M. S. & Matter, K. Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein APG-2. BMC Cell Biol. 8, 49 (2007).
    • (2007) BMC Cell Biol , vol.8 , pp. 49
    • Aijaz, S.1    Sanchez-Heras, E.2    Balda, M.S.3    Matter, K.4
  • 149
    • 4444352406 scopus 로고    scopus 로고
    • A junctional problem of apical proportions: Epithelial tube-size control by septate junctions in the Drosophila tracheal system
    • Wu, V. M. & Beitel, G. J. A junctional problem of apical proportions: epithelial tube-size control by septate junctions in the Drosophila tracheal system. Curr. Opin. Cell Biol. 16, 493-499 (2004).
    • (2004) Curr. Opin. Cell Biol , vol.16 , pp. 493-499
    • Wu, V.M.1    Beitel, G.J.2


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