메뉴 건너뛰기




Volumn 457, Issue 6, 2010, Pages 635-642

Loss of cell polarity protein Lgl2 in foveolar-type gastric dysplasia: Correlation with expression of the apical marker aPKC-zeta

Author keywords

Adenocarcinoma; aPKC; Foveolar type; Gastric dysplasia; Lgl2; Stomach

Indexed keywords

ATYPICAL PROTEIN KINASE C ZETA; LETHAL GIANT LARVAE 2 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 78651326308     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-010-0990-9     Document Type: Article
Times cited : (13)

References (41)
  • 1
    • 35748952830 scopus 로고    scopus 로고
    • Gastric preneoplastic lesions and epithelial dysplasia
    • Lauwers GY, Srivastava A (2007) Gastric preneoplastic lesions and epithelial dysplasia. Gastroenterol Clin North Am 36:813-829
    • (2007) Gastroenterol Clin North Am , vol.36 , pp. 813-829
    • Lauwers, G.Y.1    Srivastava, A.2
  • 2
    • 0027967898 scopus 로고
    • Precursors of gastric carcinoma: A critical review with a brief description of early (curable) gastric cancer
    • Antonioli DA (1994) Precursors of gastric carcinoma: a critical review with a brief description of early (curable) gastric cancer. Hum Pathol 25:994-1005
    • (1994) Hum Pathol , vol.25 , pp. 994-1005
    • Antonioli, D.A.1
  • 3
    • 41449111592 scopus 로고    scopus 로고
    • Adenomatous and foveolar gastric dysplasia: Distinct patterns of mucin expression and background intestinal metaplasia
    • Park DY, Srivastava A, Kim GH et al (2008) Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. Am J Surg Pathol 32:524-533
    • (2008) Am J Surg Pathol , vol.32 , pp. 524-533
    • Park, D.Y.1    Srivastava, A.2    Kim, G.H.3
  • 4
    • 0032719406 scopus 로고    scopus 로고
    • Gastric epithelial dysplasia
    • Lauwers GY, Riddell RH (1999) Gastric epithelial dysplasia. Gut 45:784-790
    • (1999) Gut , vol.45 , pp. 784-790
    • Lauwers, G.Y.1    Riddell, R.H.2
  • 5
    • 0033980995 scopus 로고    scopus 로고
    • Gastric dysplasia: The Padova international classification
    • Rugge M, Correa P, Dixon MF et al (2000) Gastric dysplasia: the Padova international classification. Am J Surg Pathol 24:167-176
    • (2000) Am J Surg Pathol , vol.24 , pp. 167-176
    • Rugge, M.1    Correa, P.2    Dixon, M.F.3
  • 6
    • 4043170088 scopus 로고    scopus 로고
    • Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors
    • Bilder D (2004) Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev 18:1909-1925
    • (2004) Genes Dev , vol.18 , pp. 1909-1925
    • Bilder, D.1
  • 7
    • 56349098933 scopus 로고    scopus 로고
    • Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
    • Zhan L, Rosenberg A, Bergami KC et al (2008) Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 135:865-878
    • (2008) Cell , vol.135 , pp. 865-878
    • Zhan, L.1    Rosenberg, A.2    Bergami, K.C.3
  • 8
    • 0037318955 scopus 로고    scopus 로고
    • Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
    • Albertson R, Doe CQ (2003) Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry. Nat Cell Biol 5:166-170
    • (2003) Nat Cell Biol , vol.5 , pp. 166-170
    • Albertson, R.1    Doe, C.Q.2
  • 9
    • 4344648897 scopus 로고    scopus 로고
    • Dare to be different: Asymmetric cell division in Drosophila. C. elegans and vertebrates
    • Betschinger J, Knoblich JA (2004) Dare to be different: asymmetric cell division in Drosophila. C. elegans and vertebrates. Curr Biol 14:R674-R685
    • (2004) Curr Biol , vol.14
    • Betschinger, J.1    Knoblich, J.A.2
  • 10
    • 0037385561 scopus 로고    scopus 로고
    • A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl
    • Plant PJ, Fawcett JP, Lin DC et al (2003) A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nat Cell Biol 5:301-308
    • (2003) Nat Cell Biol , vol.5 , pp. 301-308
    • Plant, P.J.1    Fawcett, J.P.2    Lin, D.C.3
  • 11
    • 0038032917 scopus 로고    scopus 로고
    • Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity
    • Yamanaka T, Horikoshi Y, Sugiyama Y et al (2003) Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity. Curr Biol 13:734-743
    • (2003) Curr Biol , vol.13 , pp. 734-743
    • Yamanaka, T.1    Horikoshi, Y.2    Sugiyama, Y.3
  • 12
    • 16844362974 scopus 로고    scopus 로고
    • APKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development
    • Chalmers AD, Pambos M, Mason J et al (2005) aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development. Development 132:977-986
    • (2005) Development , vol.132 , pp. 977-986
    • Chalmers, A.D.1    Pambos, M.2    Mason, J.3
  • 13
    • 2942626082 scopus 로고    scopus 로고
    • Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis
    • Hutterer A, Betschinger J, Petronczki M et al (2004) Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev Cell 6:845-854
    • (2004) Dev Cell , vol.6 , pp. 845-854
    • Hutterer, A.1    Betschinger, J.2    Petronczki, M.3
  • 14
    • 22944450057 scopus 로고    scopus 로고
    • Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis
    • Zhang X, Wang P, Gangar A et al (2005) Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol 170:273-283
    • (2005) J Cell Biol , vol.170 , pp. 273-283
    • Zhang, X.1    Wang, P.2    Gangar, A.3
  • 15
    • 0018099247 scopus 로고
    • Malignant neoplasms of genetic origin in Drosophila melanogaster
    • Gateff E (1978) Malignant neoplasms of genetic origin in Drosophila melanogaster. Science 200:1448-1459
    • (1978) Science , vol.200 , pp. 1448-1459
    • Gateff, E.1
  • 16
    • 0034617129 scopus 로고    scopus 로고
    • Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
    • Bilder D, Li M, Perrimon N (2000) Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289:113-116
    • (2000) Science , vol.289 , pp. 113-116
    • Bilder, D.1    Li, M.2    Perrimon, N.3
  • 17
    • 9644265474 scopus 로고    scopus 로고
    • The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo
    • Grifoni D, Garoia F, Schimanski CC et al (2004) The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo. Oncogene 23:8688-8694
    • (2004) Oncogene , vol.23 , pp. 8688-8694
    • Grifoni, D.1    Garoia, F.2    Schimanski, C.C.3
  • 18
    • 21044453012 scopus 로고    scopus 로고
    • Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer
    • Schimanski CC, Schmitz G, Kashyap A et al (2005) Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer. Oncogene 24:3100-3109
    • (2005) Oncogene , vol.24 , pp. 3100-3109
    • Schimanski, C.C.1    Schmitz, G.2    Kashyap, A.3
  • 19
    • 67650661180 scopus 로고    scopus 로고
    • Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: An immunohistochemical study
    • Lisovsky M, Dresser K, Baker S et al (2009) Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: an immunohistochemical study. Mod Pathol 22:977-984
    • (2009) Mod Pathol , vol.22 , pp. 977-984
    • Lisovsky, M.1    Dresser, K.2    Baker, S.3
  • 21
    • 0027367620 scopus 로고
    • Gastritis in patients on non-steroidal anti-inflammatory drugs
    • Quinn CM, Bjarnason I, Price AB (1993) Gastritis in patients on non-steroidal anti-inflammatory drugs. Histopathology 23:341-348
    • (1993) Histopathology , vol.23 , pp. 341-348
    • Quinn, C.M.1    Bjarnason, I.2    Price, A.B.3
  • 22
    • 44949224229 scopus 로고    scopus 로고
    • Gastric epithelial dysplasia: The Western perspective
    • Srivastava A, Lauwers GY (2008) Gastric epithelial dysplasia: the Western perspective. Dig Liver Dis 40:641-649
    • (2008) Dig Liver Dis , vol.40 , pp. 641-649
    • Srivastava, A.1    Lauwers, G.Y.2
  • 23
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Lauren P (1965) The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 64:31-49
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 25
    • 0035888163 scopus 로고    scopus 로고
    • MUC gene expression and histogenesis of adenocarcinoma of the stomach
    • Tsukashita S, Kushima R, Bamba M (2001) MUC gene expression and histogenesis of adenocarcinoma of the stomach. Int J Cancer 94:166-170
    • (2001) Int J Cancer , vol.94 , pp. 166-170
    • Tsukashita, S.1    Kushima, R.2    Bamba, M.3
  • 26
    • 33751292686 scopus 로고    scopus 로고
    • Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: Clinicopathologic significance and genetic background
    • Tajima Y, Yamazaki K, Makino R (2006) Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background. Clin Cancer Res 12:6469-6479
    • (2006) Clin Cancer Res , vol.12 , pp. 6469-6479
    • Tajima, Y.1    Yamazaki, K.2    Makino, R.3
  • 27
    • 73949127446 scopus 로고    scopus 로고
    • CDX2 expression in the intestinal-type gastric epithelial neoplasia: Frequency and significance
    • Park DY, Srivastava A, Kim GH (2010) CDX2 expression in the intestinal-type gastric epithelial neoplasia: frequency and significance. Mod Pathol 23:54-61
    • (2010) Mod Pathol , vol.23 , pp. 54-61
    • Park, D.Y.1    Srivastava, A.2    Kim, G.H.3
  • 28
    • 67549148933 scopus 로고    scopus 로고
    • Nonadenomatous dysplasia in Barrett esophagus: A clinical, pathologic, and DNA content flow cytometric study
    • Rucker-Schmidt RL, Sanchez CA, Blount PL (2009) Nonadenomatous dysplasia in Barrett esophagus: a clinical, pathologic, and DNA content flow cytometric study. Am J Surg Pathol 33:886-893
    • (2009) Am J Surg Pathol , vol.33 , pp. 886-893
    • Rucker-Schmidt, R.L.1    Sanchez, C.A.2    Blount, P.L.3
  • 29
    • 77953128254 scopus 로고    scopus 로고
    • Foveolar type dysplasia in Barrett esophagus
    • Brown IS, Whiteman DC, Lauwers GY (2010) Foveolar type dysplasia in Barrett esophagus. Mod Pathol 23:834-843
    • (2010) Mod Pathol , vol.23 , pp. 834-843
    • Brown, I.S.1    Whiteman, D.C.2    Lauwers, G.Y.3
  • 30
    • 73949135640 scopus 로고    scopus 로고
    • Grading of gastric foveolartype dysplasia in Barrett's esophagus
    • Mahajan D, Bennett AE, Liu X (2010) Grading of gastric foveolartype dysplasia in Barrett's esophagus. Mod Pathol 23:1-11
    • (2010) Mod Pathol , vol.23 , pp. 1-11
    • Mahajan, D.1    Bennett, A.E.2    Liu, X.3
  • 31
    • 0031036295 scopus 로고    scopus 로고
    • Gastric epithelial dysplasia and adenoma: Historical review andhistological criteria for grading
    • Goldstein NS, Lewin KJ (1997) Gastric epithelial dysplasia and adenoma: historical review andhistological criteria for grading. Hum Pathol 28:127-133
    • (1997) Hum Pathol , vol.28 , pp. 127-133
    • Goldstein, N.S.1    Lewin, K.J.2
  • 32
    • 0037096887 scopus 로고    scopus 로고
    • Beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer
    • Clements WM, Wang J, Sarnaik A et al (2002) beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer. Cancer Res 62:3503-3506
    • (2002) Cancer Res , vol.62 , pp. 3503-3506
    • Clements, W.M.1    Wang, J.2    Sarnaik, A.3
  • 33
    • 0026734665 scopus 로고
    • The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer
    • Horii A, Nakatsuru S, Miyoshi Y et al (1992) The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res 52:3231-3233
    • (1992) Cancer Res , vol.52 , pp. 3231-3233
    • Horii, A.1    Nakatsuru, S.2    Miyoshi, Y.3
  • 34
    • 34447521472 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer
    • Nojima M, Suzuki H, Toyota M et al (2007) Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. Oncogene 26:4699-4713
    • (2007) Oncogene , vol.26 , pp. 4699-4713
    • Nojima, M.1    Suzuki, H.2    Toyota, M.3
  • 35
    • 27644440810 scopus 로고    scopus 로고
    • Regulation of Lethal giant larvae by Dishevelled
    • Dollar GL, Weber U, Mlodzik M et al (2005) Regulation of Lethal giant larvae by Dishevelled. Nature 437:1376-1380
    • (2005) Nature , vol.437 , pp. 1376-1380
    • Dollar, G.L.1    Weber, U.2    Mlodzik, M.3
  • 36
    • 0042389458 scopus 로고    scopus 로고
    • Genetic alterations in gastric adenomas of intestinal and foveolar phenotypes
    • Abraham SC, Park SJ, Lee JH et al (2003) Genetic alterations in gastric adenomas of intestinal and foveolar phenotypes. Mod Pathol 16:786-795
    • (2003) Mod Pathol , vol.16 , pp. 786-795
    • Abraham, S.C.1    Park, S.J.2    Lee, J.H.3
  • 37
    • 0036788295 scopus 로고    scopus 로고
    • Gastric adenomas: Intestinal-type and gastric-type adenomas differ in the risk of adenocarcinoma and presence of background mucosal pathology
    • Abraham SC, Montgomery EA, Singh VK et al (2002) Gastric adenomas: intestinal-type and gastric-type adenomas differ in the risk of adenocarcinoma and presence of background mucosal pathology. Am J Surg Pathol 26:1276-1285
    • (2002) Am J Surg Pathol , vol.26 , pp. 1276-1285
    • Abraham, S.C.1    Montgomery, E.A.2    Singh, V.K.3
  • 38
    • 60249094045 scopus 로고    scopus 로고
    • Pyloric gland adenoma: An entity distinct from gastric foveolar type adenoma
    • Chen ZM, Scudiere JR, Abraham SC et al (2009) Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma. Am J Surg Pathol 33:186-193
    • (2009) Am J Surg Pathol , vol.33 , pp. 186-193
    • Chen, Z.M.1    Scudiere, J.R.2    Abraham, S.C.3
  • 40
    • 25444531988 scopus 로고    scopus 로고
    • Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer
    • Regala RP, Weems C, Jamieson L et al (2005) Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer. Cancer Res 65:8905-8911
    • (2005) Cancer Res , vol.65 , pp. 8905-8911
    • Regala, R.P.1    Weems, C.2    Jamieson, L.3
  • 41
    • 24644490121 scopus 로고    scopus 로고
    • Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer
    • Eder AM, Sui X, Rosen DG et al (2005) Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. Proc Natl Acad Sci USA 102:12519-12524
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12519-12524
    • Eder, A.M.1    Sui, X.2    Rosen, D.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.