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Volumn 15, Issue 2, 2014, Pages 137-147

Adiponectin signaling in the liver

Author keywords

Adiponectin; Amino acids; Autophagy; Blood glucose; Diabetes; Fatty acids; Glucose production; Insulin; Liver; SOGA

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; CADHERIN; CERAMIDASE; GLUCOSE; ADIPONECTIN RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84901457990     PISSN: 13899155     EISSN: 15732606     Source Type: Journal    
DOI: 10.1007/s11154-013-9280-6     Document Type: Review
Times cited : (122)

References (95)
  • 1
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem. 1995;270(45):26746-9.
    • (1995) J Biol Chem , vol.270 , Issue.45 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 2
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem. 1996;271(18):10697-703.
    • (1996) J Biol Chem , vol.271 , Issue.18 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 3
    • 0032779351 scopus 로고    scopus 로고
    • Molecular mechanism of metabolic syndrome X: Contribution of adipocytokines adipocytederived bioactive substances
    • Matsuzawa Y, Funahashi T, Nakamura T. Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocytederived bioactive substances. Ann N YAcad Sci. 1999;892:146-54.
    • (1999) Ann N YAcad Sci , vol.892 , pp. 146-154
    • Matsuzawa, Y.1    Funahashi, T.2    Nakamura, T.3
  • 4
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism
    • Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab. 2002;13(2):84-9.
    • (2002) Trends Endocrinol Metab , vol.13 , Issue.2 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 5
    • 35549006843 scopus 로고    scopus 로고
    • Activation of nuclear factor kappaB by high molecular weight and globular adiponectin
    • Haugen F, Drevon CA. Activation of nuclear factor kappaB by high molecular weight and globular adiponectin. Endocrinol. 2007;148(11):5478-86.
    • (2007) Endocrinol , vol.148 , Issue.11 , pp. 5478-5486
    • Haugen, F.1    Drevon, C.A.2
  • 6
    • 42449113834 scopus 로고    scopus 로고
    • Plasma adiponectin complexes have distinct biochemical characteristics
    • Schraw T, Wang ZV, Halberg N, Hawkins M, Scherer PE. Plasma adiponectin complexes have distinct biochemical characteristics. Endocrinol. 2008;149(5):2270-82.
    • (2008) Endocrinol , vol.149 , Issue.5 , pp. 2270-2282
    • Schraw, T.1    Wang, Z.V.2    Halberg, N.3    Hawkins, M.4    Scherer, P.E.5
  • 7
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A. 2001;98(4):2005-10.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.4 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.S.2    Javorschi, S.3    Ebbets-Reed, D.4    Erickson, M.R.5    Yen, F.T.6
  • 8
    • 0037984387 scopus 로고    scopus 로고
    • Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity
    • Pajvani UB, Du X, Combs TP, Berg AH, Rajala MW, Schulthess T, et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity. J Biol Chem. 2003;278(11):9073-85.
    • (2003) J Biol Chem , vol.278 , Issue.11 , pp. 9073-9085
    • Pajvani, U.B.1    Du, X.2    Combs, T.P.3    Berg, A.H.4    Rajala, M.W.5    Schulthess, T.6
  • 9
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med. 2001;7(8):947-53.
    • (2001) Nat Med , vol.7 , Issue.8 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 10
    • 0029148426 scopus 로고
    • Cardiac and adipose tissue abnormalilties but not diabetes in mice deficient in GLUT4
    • Katz EB, Stenbit AE, Hatton K, DePinho R, Cahrron MJ. Cardiac and adipose tissue abnormalilties but not diabetes in mice deficient in GLUT4. Nature. 1995;377:151-5.
    • (1995) Nature , vol.377 , pp. 151-155
    • Katz, E.B.1    Stenbit, A.E.2    Hatton, K.3    DePinho, R.4    Cahrron, M.J.5
  • 11
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Investig. 2001;108(12):1875-81.
    • (2001) J Clin Investig , vol.108 , Issue.12 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3    Scherer, P.E.4    Rossetti, L.5
  • 12
    • 9144263120 scopus 로고    scopus 로고
    • A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity
    • Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, et al. A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology. 2004;145(1):367-83.
    • (2004) Endocrinology , vol.145 , Issue.1 , pp. 367-383
    • Combs, T.P.1    Pajvani, U.B.2    Berg, A.H.3    Lin, Y.4    Jelicks, L.A.5    Laplante, M.6
  • 13
    • 33646346627 scopus 로고    scopus 로고
    • Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists
    • Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, et al. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J Biol Chem. 2006;281(5):2654-60.
    • (2006) J Biol Chem , vol.281 , Issue.5 , pp. 2654-2660
    • Nawrocki, A.R.1    Rajala, M.W.2    Tomas, E.3    Pajvani, U.B.4    Saha, A.K.5    Trumbauer, M.E.6
  • 14
    • 78651260799 scopus 로고    scopus 로고
    • Receptor-mediated activation of ceramidase activity inititates the pleiotropic actions of adiponectin
    • Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, et al. Receptor-mediated activation of ceramidase activity inititates the pleiotropic actions of adiponectin. Nat Med. 2011;17(1):55-65.
    • (2011) Nat Med , vol.17 , Issue.1 , pp. 55-65
    • Holland, W.L.1    Miller, R.A.2    Wang, Z.V.3    Sun, K.4    Barth, B.M.5    Bui, H.H.6
  • 15
    • 0037205414 scopus 로고    scopus 로고
    • Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity
    • Wang Y, Xu A, Knight C, Xu LY, Cooper GJ. Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem. 2002;277(22):19521-9.
    • (2002) J Biol Chem , vol.277 , Issue.22 , pp. 19521-19529
    • Wang, Y.1    Xu, A.2    Knight, C.3    Xu, L.Y.4    Cooper, G.J.5
  • 17
    • 84901457748 scopus 로고    scopus 로고
    • Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
    • Mynarcick DC, Combs TP, McNurlan MA, Scherer PE, Komaroff E, Gelato MC. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. JAIDS. 2002;31(5):506-13.
    • (2002) JAIDS , vol.31 , Issue.5 , pp. 506-513
    • Mynarcick, D.C.1    Combs, T.P.2    McNurlan, M.A.3    Scherer, P.E.4    Komaroff, E.5    Gelato, M.C.6
  • 18
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: A potential mechanism of insulin sensitization
    • Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology. 2002;143(3):998-1007.
    • (2002) Endocrinology , vol.143 , Issue.3 , pp. 998-1007
    • Combs, T.P.1    Wagner, J.A.2    Berger, J.3    Doebber, T.4    Wang, W.J.5    Zhang, B.B.6
  • 19
    • 33947657925 scopus 로고    scopus 로고
    • Do low levels of circulating adiponectin represent a biomarker or just another risk factor for the metabolic syndrome?
    • Brooks NL, Moore KS, Clark RD, Perfetti MT, Trent CM, Combs TP. Do low levels of circulating adiponectin represent a biomarker or just another risk factor for the metabolic syndrome? Diabetes Obes Metab. 2007;9(3):246-58.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.3 , pp. 246-258
    • Brooks, N.L.1    Moore, K.S.2    Clark, R.D.3    Perfetti, M.T.4    Trent, C.M.5    Combs, T.P.6
  • 20
    • 84877329207 scopus 로고    scopus 로고
    • PPARgamma signaling and metabolism: The good the bad and the future
    • Ahmadian M, Suh JM, Hah N, Liddle C, Atkins AR, Downes M, et al. PPARgamma signaling and metabolism: the good the bad and the future. Nat Med. 2013;99:557-66.
    • (2013) Nat Med , vol.99 , pp. 557-566
    • Ahmadian, M.1    Suh, J.M.2    Hah, N.3    Liddle, C.4    Atkins, A.R.5    Downes, M.6
  • 21
    • 1642299047 scopus 로고    scopus 로고
    • Adipose tissue adiponectin production and adiponectin seum concentration in human obesity and insulin resistance
    • Hoffstedt J, Arvidsson E, Sjolin E,WahlenK, Arner P. Adipose tissue adiponectin production and adiponectin seum concentration in human obesity and insulin resistance. J Clin Endocrinol Metab. 2004;89(3):1391-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.3 , pp. 1391-1396
    • Hoffstedt, J.1    Arvidsson, E.2    Sjolin, E.3    Wahlen, K.4    Arner, P.5
  • 22
    • 3142761477 scopus 로고    scopus 로고
    • T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
    • Hug C, Wang J, Ahmad NS, Bogan JS, Tsao TS, Lodish HF. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci. 2004;101(28):10308-13.
    • (2004) Proc Natl Acad Sci , vol.101 , Issue.28 , pp. 10308-10313
    • Hug, C.1    Wang, J.2    Ahmad, N.S.3    Bogan, J.S.4    Tsao, T.S.5    Lodish, H.F.6
  • 23
    • 47249149299 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells
    • Chan CY, Lee JM, Chan PC, Ng IO. Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. Cancer Cell Biol. 2008;123(5):1043-52.
    • (2008) Cancer Cell Biol , vol.123 , Issue.5 , pp. 1043-1052
    • Chan, C.Y.1    Lee, J.M.2    Chan, P.C.3    Ng, I.O.4
  • 24
    • 0026646522 scopus 로고
    • Glycosyl phosphatidylinositol-anchored T-cadherin mediates calcium-dependent, homophilic cell adhesion
    • Vestal DJ, Ranscht B. Glycosyl phosphatidylinositol-anchored T-cadherin mediates calcium-dependent, homophilic cell adhesion. J Cell Biol. 1992;119(2):451-61.
    • (1992) J Cell Biol , vol.119 , Issue.2 , pp. 451-461
    • Vestal, D.J.1    Ranscht, B.2
  • 26
    • 0032511170 scopus 로고    scopus 로고
    • T-cadherin and signal-transducing moleculaes co-localize in caveolin-rich membrane domains of vascular smooth muscle cells
    • Philippova MP, Bochkov VN, Stambolsky DV, Tkachuk VA, Resink TJ. T-cadherin and signal-transducing moleculaes co-localize in caveolin-rich membrane domains of vascular smooth muscle cells. FEBS Lett. 1998;429:207-10.
    • (1998) FEBS Lett , vol.429 , pp. 207-210
    • Philippova, M.P.1    Bochkov, V.N.2    Stambolsky, D.V.3    Tkachuk, V.A.4    Resink, T.J.5
  • 27
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature. 2003;423(6941):762-9.
    • (2003) Nature , vol.423 , Issue.6941 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 28
    • 33744972277 scopus 로고    scopus 로고
    • APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function
    • Mao X, Kikani CK, Riojas RA, Langlais P, Wang L, Ramos FJ, et al. APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat Cell Biol. 2006;8(5):516-23.
    • (2006) Nat Cell Biol , vol.8 , Issue.5 , pp. 516-523
    • Mao, X.1    Kikani, C.K.2    Riojas, R.A.3    Langlais, P.4    Wang, L.5    Ramos, F.J.6
  • 29
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med. 2002;8(11):1288-95.
    • (2002) Nat Med , vol.8 , Issue.11 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 31
    • 48249117609 scopus 로고    scopus 로고
    • Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism
    • Qiao L, Zou C, van der Westhuyzen DR, Shao J. Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism. Diabetes. 2008;57(7):1824-33.
    • (2008) Diabetes , vol.57 , Issue.7 , pp. 1824-1833
    • Qiao, L.1    Zou, C.2    Van Der Westhuyzen, D.R.3    Shao, J.4
  • 32
    • 36849073063 scopus 로고    scopus 로고
    • Low utilization of circulating glucose after food withdrawal in Snell dwarf mice
    • Brooks NL, Trent CM, Raetzsch CF, Flurkey K, Boysen G, Perfetti MT, et al. Low utilization of circulating glucose after food withdrawal in Snell dwarf mice. J Biol Chem. 2007;282(48):35069-77.
    • (2007) J Biol Chem , vol.282 , Issue.48 , pp. 35069-35077
    • Brooks, N.L.1    Trent, C.M.2    Raetzsch, C.F.3    Flurkey, K.4    Boysen, G.5    Perfetti, M.T.6
  • 33
    • 33847080728 scopus 로고    scopus 로고
    • AMP-activated protein kinase in metabolic control and insulin signaling
    • Towler MC, Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res. 2007;100(3):328-41.
    • (2007) Circ Res , vol.100 , Issue.3 , pp. 328-341
    • Towler, M.C.1    Hardie, D.G.2
  • 34
    • 58249105213 scopus 로고    scopus 로고
    • APPL1: Role in adiponectin signaling and beyond
    • Deepa SS, Dong LQ. APPL1: role in adiponectin signaling and beyond. Am J Physiol Endocrinol Metab. 2009;296(1):E22-36.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , Issue.1
    • Deepa, S.S.1    Dong, L.Q.2
  • 35
    • 70450265225 scopus 로고    scopus 로고
    • Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
    • Wang C, Xin X, Xiang R, Ramos FJ, Liu M, Lee HJ, et al. Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells. J Biol Chem. 2009;284(46):31608-15.
    • (2009) J Biol Chem , vol.284 , Issue.46 , pp. 31608-31615
    • Wang, C.1    Xin, X.2    Xiang, R.3    Ramos, F.J.4    Liu, M.5    Lee, H.J.6
  • 36
    • 0033815967 scopus 로고    scopus 로고
    • Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
    • Woods A, Azzout-Marniche D, Foretz M, Stein SC, Lemarchand P, Ferre P, et al. Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol. 2000;20(18):6704-11.
    • (2000) Mol Cell Biol , vol.20 , Issue.18 , pp. 6704-6711
    • Woods, A.1    Azzout-Marniche, D.2    Foretz, M.3    Stein, S.C.4    Lemarchand, P.5    Ferre, P.6
  • 37
    • 43549093962 scopus 로고    scopus 로고
    • High molecular weight adiponectin activates AMPK and suppresses cytokine-induced NF-kappaB activation in vascular endothelial cells
    • Hattori Y, Nakano Y, Hattori S, Tomizawa A, Inukai K, Kasai K. High molecular weight adiponectin activates AMPK and suppresses cytokine-induced NF-kappaB activation in vascular endothelial cells. FEBS Lett. 2008;582(12):1719-24.
    • (2008) FEBS Lett , vol.582 , Issue.12 , pp. 1719-1724
    • Hattori, Y.1    Nakano, Y.2    Hattori, S.3    Tomizawa, A.4    Inukai, K.5    Kasai, K.6
  • 38
    • 69249147344 scopus 로고    scopus 로고
    • Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways
    • Zhou L, Deepa SS, Etzler JC, Ryu J, Mao X, Fang Q, et al. Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways. J Biol Chem. 2009;284(33):22426-35.
    • (2009) J Biol Chem , vol.284 , Issue.33 , pp. 22426-22435
    • Zhou, L.1    Deepa, S.S.2    Etzler, J.C.3    Ryu, J.4    Mao, X.5    Fang, Q.6
  • 39
    • 77951872309 scopus 로고    scopus 로고
    • Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1
    • Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, et al. Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1. Nature. 2010;464(7293):1313-9.
    • (2010) Nature , vol.464 , Issue.7293 , pp. 1313-1319
    • Iwabu, M.1    Yamauchi, T.2    Okada-Iwabu, M.3    Sato, K.4    Nakagawa, T.5    Funata, M.6
  • 40
    • 77957769313 scopus 로고    scopus 로고
    • Adiponectin receptor binding proteins-recent advances in elucidating adiponectin signalling pathways
    • Buechler C, Wanninger J, Neumeier M. Adiponectin receptor binding proteins-recent advances in elucidating adiponectin signalling pathways. FEBS Lett. 2010;584(20):4280-6.
    • (2010) FEBS Lett , vol.584 , Issue.20 , pp. 4280-4286
    • Buechler, C.1    Wanninger, J.2    Neumeier, M.3
  • 41
    • 79955618001 scopus 로고    scopus 로고
    • AMP-activated protein kinase and metabolic control
    • Viollet B, Andreelli F. AMP-activated protein kinase and metabolic control. Handb Exp Pharmacol. 2011;203:303-30.
    • (2011) Handb Exp Pharmacol , vol.203 , pp. 303-330
    • Viollet, B.1    Andreelli, F.2
  • 42
    • 0142091454 scopus 로고    scopus 로고
    • Ceramide disables 3- phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism
    • Powell DJ, Hajduch E, Kular G, Hundal HS. Ceramide disables 3- phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol Cell Biol. 2003;23(21):7794-808.
    • (2003) Mol Cell Biol , vol.23 , Issue.21 , pp. 7794-7808
    • Powell, D.J.1    Hajduch, E.2    Kular, G.3    Hundal, H.S.4
  • 43
    • 61549109860 scopus 로고    scopus 로고
    • Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
    • Mukhopadhyay A, Saddoughi SA, Song P, Sultan I, Ponnusamy S, Senkal CE, et al. Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling. FASEB J. 2009;23(3):751-63.
    • (2009) FASEB J , vol.23 , Issue.3 , pp. 751-763
    • Mukhopadhyay, A.1    Saddoughi, S.A.2    Song, P.3    Sultan, I.4    Ponnusamy, S.5    Senkal, C.E.6
  • 45
    • 46949104885 scopus 로고    scopus 로고
    • "Inside-out" signaling of sphingosine-1-phosphate: Therapeutic targets
    • Takabe K, Paugh SW, Milstien S, Spiegel S. "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol Rev. 2008;60(2):181-95.
    • (2008) Pharmacol Rev , vol.60 , Issue.2 , pp. 181-195
    • Takabe, K.1    Paugh, S.W.2    Milstien, S.3    Spiegel, S.4
  • 46
  • 47
    • 77955300117 scopus 로고    scopus 로고
    • Increased hepatic insulin action in diet-induced obese mice following inhibition of glucosylceramide synthase
    • Yew NS, Zhao H, Hong EG, Wu IH, Przybylska M, Siegel C, et al. Increased hepatic insulin action in diet-induced obese mice following inhibition of glucosylceramide synthase. PLoS One. 2010;5(6):e11239.
    • (2010) PLoS One , vol.5 , Issue.6
    • Yew, N.S.1    Zhao, H.2    Hong, E.G.3    Wu, I.H.4    Przybylska, M.5    Siegel, C.6
  • 48
    • 79955487247 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
    • Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, et al. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest. 2011;121(5):1858-70.
    • (2011) J Clin Invest , vol.121 , Issue.5 , pp. 1858-1870
    • Holland, W.L.1    Bikman, B.T.2    Wang, L.P.3    Yuguang, G.4    Sargent, K.M.5    Bulchand, S.6
  • 51
    • 45149106053 scopus 로고    scopus 로고
    • Sphingolipids, insulin resistance, and metabolic disease: New insights from in vivo manipulation of sphingolipid metabolism
    • Holland WL, Summers SA. Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev. 2008;29(4):381-402.
    • (2008) Endocr Rev , vol.29 , Issue.4 , pp. 381-402
    • Holland, W.L.1    Summers, S.A.2
  • 52
    • 84866079242 scopus 로고    scopus 로고
    • The role of adiponectin in cancer: A review of current evidence
    • Dalamaga M, Diakopoulos KN, Mantzoros CS. The role of adiponectin in cancer: a review of current evidence. Endocr Rev. 2012;33(4):547-94.
    • (2012) Endocr Rev , vol.33 , Issue.4 , pp. 547-594
    • Dalamaga, M.1    Diakopoulos, K.N.2    Mantzoros, C.S.3
  • 53
    • 79957902675 scopus 로고    scopus 로고
    • Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling
    • Miller RA, Chu Q, Le Lay J, Scherer PE, Ahima RS, Kaestner KH, et al. Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. J Clin Investig. 2011;121(6):2518-28.
    • (2011) J Clin Investig , vol.121 , Issue.6 , pp. 2518-2528
    • Miller, R.A.1    Chu, Q.2    Le Lay, J.3    Scherer, P.E.4    Ahima, R.S.5    Kaestner, K.H.6
  • 54
    • 10744224100 scopus 로고    scopus 로고
    • Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats
    • Shklyaev S, Aslanidi G, Tennant M, Prima V, Kohlbrenner E, Kroutov V, et al. Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats. Proc Natl Acad Sci U S A. 2003;100(24):14217-22.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.24 , pp. 14217-14222
    • Shklyaev, S.1    Aslanidi, G.2    Tennant, M.3    Prima, V.4    Kohlbrenner, E.5    Kroutov, V.6
  • 55
    • 84881476148 scopus 로고    scopus 로고
    • Hydrodynamic delivery of adiponectin and adiponectin receptor 2 gene blocks high-fat diet-induced obesity and insulin resistance
    • Ma Y, Liu D. Hydrodynamic delivery of adiponectin and adiponectin receptor 2 gene blocks high-fat diet-induced obesity and insulin resistance. Gene Ther. 2013.
    • (2013) Gene Ther
    • Ma, Y.1    Liu, D.2
  • 56
    • 33645884425 scopus 로고    scopus 로고
    • Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin
    • Andreelli F, Foretz M, Knauf C, Cani PD, Perrin C, Iglesias MA, et al. Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology. 2006;147(5):2432-41.
    • (2006) Endocrinology , vol.147 , Issue.5 , pp. 2432-2441
    • Andreelli, F.1    Foretz, M.2    Knauf, C.3    Cani, P.D.4    Perrin, C.5    Iglesias, M.A.6
  • 57
    • 0035855858 scopus 로고    scopus 로고
    • Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    • Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature. 2001;413(6852):131-8.
    • (2001) Nature , vol.413 , Issue.6852 , pp. 131-138
    • Yoon, J.C.1    Puigserver, P.2    Chen, G.3    Donovan, J.4    Wu, Z.5    Rhee, J.6
  • 58
    • 28844433635 scopus 로고    scopus 로고
    • The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
    • Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science. 2005;310(5754):1642-6.
    • (2005) Science , vol.310 , Issue.5754 , pp. 1642-1646
    • Shaw, R.J.1    Lamia, K.A.2    Vasquez, D.3    Koo, S.H.4    Bardeesy, N.5    Depinho, R.A.6
  • 59
    • 27144506185 scopus 로고    scopus 로고
    • The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
    • Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature. 2005;437(7062):1109-11.
    • (2005) Nature , vol.437 , Issue.7062 , pp. 1109-1111
    • Koo, S.H.1    Flechner, L.2    Qi, L.3    Zhang, X.4    Screaton, R.A.5    Jeffries, S.6
  • 60
    • 33748748698 scopus 로고    scopus 로고
    • Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase
    • Berasi SP, Huard C, Li D, Shih HH, Sun Y, Zhong W, et al. Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase. J Biol Chem. 2006;281(37):27167-77.
    • (2006) J Biol Chem , vol.281 , Issue.37 , pp. 27167-27177
    • Berasi, S.P.1    Huard, C.2    Li, D.3    Shih, H.H.4    Sun, Y.5    Zhong, W.6
  • 61
    • 9444287616 scopus 로고    scopus 로고
    • The alpha2-5′AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading
    • Jorgensen SB, Nielsen JN, Birk JB, Olsen GS, Viollet B, Andreelli F, et al. The alpha2-5′AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading. Diabetes. 2004;53(12):3074-81.
    • (2004) Diabetes , vol.53 , Issue.12 , pp. 3074-3081
    • Jorgensen, S.B.1    Nielsen, J.N.2    Birk, J.B.3    Olsen, G.S.4    Viollet, B.5    Andreelli, F.6
  • 62
    • 0035861644 scopus 로고    scopus 로고
    • 5′-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside
    • Jakobsen SN, Hardie DG, Morrice N, Tornqvist HE. 5′-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside. J Biol Chem. 2001;276(50):46912-6.
    • (2001) J Biol Chem , vol.276 , Issue.50 , pp. 46912-46916
    • Jakobsen, S.N.1    Hardie, D.G.2    Morrice, N.3    Tornqvist, H.E.4
  • 63
    • 79953765855 scopus 로고    scopus 로고
    • Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway
    • Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, et al. Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab. 2011;13(4):401-12.
    • (2011) Cell Metab , vol.13 , Issue.4 , pp. 401-412
    • Awazawa, M.1    Ueki, K.2    Inabe, K.3    Yamauchi, T.4    Kubota, N.5    Kaneko, K.6
  • 64
    • 0032493725 scopus 로고    scopus 로고
    • Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin
    • Dickens M, Svitek CA, Culbert AA, O'Brien RM, Tavare JM. Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin. J Biol Chem. 1998;273(32):20144-9.
    • (1998) J Biol Chem , vol.273 , Issue.32 , pp. 20144-20149
    • Dickens, M.1    Svitek, C.A.2    Culbert, A.A.3    O'Brien, R.M.4    Tavare, J.M.5
  • 65
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • Nakae J, Kitamura T, Silver DL, Accili D. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest. 2001;108(9):1359-67.
    • (2001) J Clin Invest , vol.108 , Issue.9 , pp. 1359-1367
    • Nakae, J.1    Kitamura, T.2    Silver, D.L.3    Accili, D.4
  • 66
    • 0038242819 scopus 로고    scopus 로고
    • TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
    • Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science. 2003;300(5625):1574-7.
    • (2003) Science , vol.300 , Issue.5625 , pp. 1574-1577
    • Du, K.1    Herzig, S.2    Kulkarni, R.N.3    Montminy, M.4
  • 68
    • 65449161015 scopus 로고    scopus 로고
    • APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice
    • Cheng KK, Iglesias MA, Lam KS, Wang Y, Sweeney G, Zhu W, et al. APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice. Cell Metab. 2009;9(5):417-27.
    • (2009) Cell Metab , vol.9 , Issue.5 , pp. 417-427
    • Cheng, K.K.1    Iglesias, M.A.2    Lam, K.S.3    Wang, Y.4    Sweeney, G.5    Zhu, W.6
  • 69
    • 0028198433 scopus 로고
    • Inhibition of hepatic gluconeogenesis by nitric oxide: A comparison with endotoxic shock
    • Horton RA, Ceppi ED, Knowles RG, Titheradge MA. Inhibition of hepatic gluconeogenesis by nitric oxide: a comparison with endotoxic shock. Biochem J. 1994;299(Pt 3):735-9.
    • (1994) Biochem J , vol.299 , Issue.PART 3 , pp. 735-739
    • Horton, R.A.1    Ceppi, E.D.2    Knowles, R.G.3    Titheradge, M.A.4
  • 70
    • 80755168862 scopus 로고    scopus 로고
    • APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice
    • Wang Y, Cheng KK, Lam KS, Wu D, Wang Y, Huang Y, et al. APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice. Diabetes. 2011;60(11):3044-54.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 3044-3054
    • Wang, Y.1    Cheng, K.K.2    Lam, K.S.3    Wu, D.4    Wang, Y.5    Huang, Y.6
  • 71
    • 0037119375 scopus 로고    scopus 로고
    • Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30)
    • Tsao TS, Murrey HE, Hug C, Lee DH, Lodish HF. Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem. 2002;277(33):29359- 62.
    • (2002) J Biol Chem , vol.277 , Issue.33 , pp. 29359-29362
    • Tsao, T.S.1    Murrey, H.E.2    Hug, C.3    Lee, D.H.4    Lodish, H.F.5
  • 72
    • 0027439440 scopus 로고
    • Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes
    • Geller DA, Nussler AK, Di Silvio M, Lowenstein CJ, Shapiro RA, Wang SC, et al. Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci U S A. 1993;90(2):522-6.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.2 , pp. 522-526
    • Geller, D.A.1    Nussler, A.K.2    Di Silvio, M.3    Lowenstein, C.J.4    Shapiro, R.A.5    Wang, S.C.6
  • 73
    • 0034644719 scopus 로고    scopus 로고
    • NF-kappa B inhibits glucocorticoid and cAMP-mediated expression of the phosphoenolpyruvate carboxykinase gene
    • Waltner-Law M, Daniels MC, Sutherland C, Granner DK. NF-kappa B inhibits glucocorticoid and cAMP-mediated expression of the phosphoenolpyruvate carboxykinase gene. J Biol Chem. 2000;275(41):31847-56.
    • (2000) J Biol Chem , vol.275 , Issue.41 , pp. 31847-31856
    • Waltner-Law, M.1    Daniels, M.C.2    Sutherland, C.3    Granner, D.K.4
  • 74
    • 4544256865 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha decreases glucose-6-phosphatase gene expression by activation of nuclear factor kappaB
    • Grempler R, Kienitz A, Werner T, Meyer M, Barthel A, Ailett F, et al. Tumour necrosis factor alpha decreases glucose-6-phosphatase gene expression by activation of nuclear factor kappaB. Biochem J. 2004;382(Pt 2):471-9.
    • (2004) Biochem J , vol.382 , Issue.PART 2 , pp. 471-479
    • Grempler, R.1    Kienitz, A.2    Werner, T.3    Meyer, M.4    Barthel, A.5    Ailett, F.6
  • 75
    • 68949192626 scopus 로고    scopus 로고
    • Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway
    • Raetzsch CF, Brooks NL, Alderman JM, Moore KS, Hosick PA, Klebanov S, et al. Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway. Hepatology. 2009;50(2):592-600.
    • (2009) Hepatology , vol.50 , Issue.2 , pp. 592-600
    • Raetzsch, C.F.1    Brooks, N.L.2    Alderman, J.M.3    Moore, K.S.4    Hosick, P.A.5    Klebanov, S.6
  • 76
    • 33645804223 scopus 로고    scopus 로고
    • Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding
    • Thakur V, Pritchard MT, McMullen MR, Nagy LE. Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding. Am J Physiol Gastrointest Liver Physiol. 2006;290(5):G998-G1007.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , Issue.5
    • Thakur, V.1    Pritchard, M.T.2    McMullen, M.R.3    Nagy, L.E.4
  • 77
    • 0033826669 scopus 로고    scopus 로고
    • Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin
    • Mittelman SD, Bergman RN. Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab. 2000;279(3):E630-7.
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , Issue.3
    • Mittelman, S.D.1    Bergman, R.N.2
  • 79
    • 0014636043 scopus 로고
    • Role of substrate in the regulation of hepatic gluconeogenesis in fasting man
    • Felig P, Marliss E, Owen OE, Cahill Jr GF. Role of substrate in the regulation of hepatic gluconeogenesis in fasting man. Adv Enzyme Regul. 1969;7:41-6.
    • (1969) Adv Enzyme Regul , vol.7 , pp. 41-46
    • Felig, P.1    Marliss, E.2    Owen, O.E.3    Cahill Jr., G.F.4
  • 80
    • 84860568860 scopus 로고    scopus 로고
    • Ubiquitin-specific protease 2 regulates hepatic gluconeogenesis and diurnal glucose metabolism through 11beta-hydroxysteroid dehydrogenase 1
    • Molusky MM, Li S, Ma D, Yu L, Lin JD. Ubiquitin-specific protease 2 regulates hepatic gluconeogenesis and diurnal glucose metabolism through 11beta-hydroxysteroid dehydrogenase 1. Diabetes. 2012;61(5):1025-35.
    • (2012) Diabetes , vol.61 , Issue.5 , pp. 1025-1035
    • Molusky, M.M.1    Li, S.2    Ma, D.3    Yu, L.4    Lin, J.D.5
  • 81
    • 77953214748 scopus 로고    scopus 로고
    • Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus
    • Penn SK, Kao AH, Schott LL, Elliott JR, Toledo FG, Kuller L, et al. Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus. J Rheumatol. 2010;37(6):1136-42.
    • (2010) J Rheumatol , vol.37 , Issue.6 , pp. 1136-1142
    • Penn, S.K.1    Kao, A.H.2    Schott, L.L.3    Elliott, J.R.4    Toledo, F.G.5    Kuller, L.6
  • 82
    • 0020510501 scopus 로고
    • Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding
    • Mortimore GE, Hutson NJ, Surmacz CA. Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding. Proc Natl Acad Sci U S A. 1983;80(8):2179-83.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , Issue.8 , pp. 2179-2183
    • Mortimore, G.E.1    Hutson, N.J.2    Surmacz, C.A.3
  • 83
    • 0016138942 scopus 로고
    • Hepatic autography in uncontrolled experimental diabetes and its relationships to insulin and glucagon
    • Amherdt M, Harris V, Renold AE, Orci L, Unger RH. Hepatic autography in uncontrolled experimental diabetes and its relationships to insulin and glucagon. J Clin Investig. 1974;54(1):188-93.
    • (1974) J Clin Investig , vol.54 , Issue.1 , pp. 188-193
    • Amherdt, M.1    Harris, V.2    Renold, A.E.3    Orci, L.4    Unger, R.H.5
  • 84
    • 0015816967 scopus 로고
    • Studies on cellular autophagocytosis. Cyclic AMP- and dibutyryl cyclic AMPstimulated autophagy in rat liver
    • Shelburne JD, Arstila AU, Trump BF. Studies on cellular autophagocytosis. Cyclic AMP- and dibutyryl cyclic AMPstimulated autophagy in rat liver. Am J Pathol. 1973;72(3):521-40.
    • (1973) Am J Pathol , vol.72 , Issue.3 , pp. 521-540
    • Shelburne, J.D.1    Arstila, A.U.2    Trump, B.F.3
  • 85
    • 0026490996 scopus 로고
    • Effects of streptozotocin-induced diabetes on rough endoplasmic reticulum and lysosomes of rat liver
    • Lenk SE, Bhat D, Blakeney W, Dunn Jr WA. Effects of streptozotocin- induced diabetes on rough endoplasmic reticulum and lysosomes of rat liver. Am J Physiol. 1992;263(5 Pt 1):E856-62.
    • (1992) Am J Physiol , vol.263 , Issue.5 PART 1
    • Lenk, S.E.1    Bhat, D.2    Blakeney, W.3    Dunn Jr., W.A.4
  • 86
    • 77957373347 scopus 로고    scopus 로고
    • The physiological deadlock between AMPK and gluconeogenesis: SOGA, a novel protein, may provide the key
    • Forbes JM. The physiological deadlock between AMPK and gluconeogenesis: SOGA, a novel protein, may provide the key. Am J Pathol. 2010;177(4):1600-2.
    • (2010) Am J Pathol , vol.177 , Issue.4 , pp. 1600-1602
    • Forbes, J.M.1
  • 87
    • 79551507263 scopus 로고    scopus 로고
    • AMPK-dependent phosphorylation of ULK1 induces autophagy
    • Zhao M, Klionsky DJ. AMPK-dependent phosphorylation of ULK1 induces autophagy. Cell Metab. 2011;13(2):119-20.
    • (2011) Cell Metab , vol.13 , Issue.2 , pp. 119-120
    • Zhao, M.1    Klionsky, D.J.2
  • 90
    • 0037383091 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms
    • Longnus SL, Wambolt RB, Parsons HL, Brownsey RW, Allard MF. 5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms. Am J Physiol Regul Integr Comp Physiol. 2003;284(4):R936-44.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284 , Issue.4
    • Longnus, S.L.1    Wambolt, R.B.2    Parsons, H.L.3    Brownsey, R.W.4    Allard, M.F.5
  • 91
    • 12744274514 scopus 로고    scopus 로고
    • Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output
    • Camacho RC, Pencek RR, Lacy DB, James FD, Donahue EP, Wasserman DH. Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output. Diabetes. 2005;54(2):373-82.
    • (2005) Diabetes , vol.54 , Issue.2 , pp. 373-382
    • Camacho, R.C.1    Pencek, R.R.2    Lacy, D.B.3    James, F.D.4    Donahue, E.P.5    Wasserman, D.H.6
  • 93
    • 38149137359 scopus 로고    scopus 로고
    • Determinants of whole-body protein metabolism in subjects with and without type 2 diabetes
    • Gougeon R, Morais JA, Chevalier S, Pereira S, Lamarche M, Marliss EB. Determinants of whole-body protein metabolism in subjects with and without type 2 diabetes. Diabetes Care. 2008;31(1):128-33.
    • (2008) Diabetes Care , vol.31 , Issue.1 , pp. 128-133
    • Gougeon, R.1    Morais, J.A.2    Chevalier, S.3    Pereira, S.4    Lamarche, M.5    Marliss, E.B.6
  • 94
    • 0028153841 scopus 로고
    • Effect of NIDDM on the kinetics of whole-body protein metabolism
    • Gougeon R, Pencharz PB, Marliss EB. Effect of NIDDM on the kinetics of whole-body protein metabolism. Diabetes. 1994;43(2):318-28.
    • (1994) Diabetes , vol.43 , Issue.2 , pp. 318-328
    • Gougeon, R.1    Pencharz, P.B.2    Marliss, E.B.3
  • 95
    • 0036728279 scopus 로고    scopus 로고
    • Elevated serum concentration of adiposederived factor, adiponectin, in patients with type 1 diabetes
    • Imagawa A, Funahashi T, Nakamura T, Moriwaki M, Tanaka S, Nishizawa H, et al. Elevated serum concentration of adiposederived factor, adiponectin, in patients with type 1 diabetes. Diabetes Care. 2002;25(9):1665-6.
    • (2002) Diabetes Care , vol.25 , Issue.9 , pp. 1665-1666
    • Imagawa, A.1    Funahashi, T.2    Nakamura, T.3    Moriwaki, M.4    Tanaka, S.5    Nishizawa, H.6


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