-
1
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
-
Greer EL, Brunet A (2009) Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell. pp. 113-127.
-
(2009)
Aging Cell.
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
3
-
-
84869488061
-
Lessons from C. elegans: signaling pathways for longevity
-
Lapierre LR, Hansen M, (2012) Lessons from C. elegans: signaling pathways for longevity. Trends Endocrinol Metab 23: 637-644.
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 637-644
-
-
Lapierre, L.R.1
Hansen, M.2
-
4
-
-
84872167604
-
Tipping the energy balance toward longevity
-
Mair W, (2013) Tipping the energy balance toward longevity. Cell Metab 17: 5-6.
-
(2013)
Cell Metab
, vol.17
, pp. 5-6
-
-
Mair, W.1
-
5
-
-
50649099122
-
Aging and survival: the genetics of life span extension by dietary restriction
-
Mair W, Dillin A (2008) Aging and survival: the genetics of life span extension by dietary restriction. Annu Rev Biochem. pp. 727-754.
-
(2008)
Annu Rev Biochem.
, pp. 727-754
-
-
Mair, W.1
Dillin, A.2
-
6
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R, (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
7
-
-
0028334880
-
daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans
-
Gottlieb S, Ruvkun G, (1994) daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. Genetics 137: 107-120.
-
(1994)
Genetics
, vol.137
, pp. 107-120
-
-
Gottlieb, S.1
Ruvkun, G.2
-
8
-
-
34249888736
-
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
-
Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A, (2007) PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447: 550-555.
-
(2007)
Nature
, vol.447
, pp. 550-555
-
-
Panowski, S.H.1
Wolff, S.2
Aguilaniu, H.3
Durieux, J.4
Dillin, A.5
-
9
-
-
33947252158
-
Origin and diversification of the basic helix-loop-helix gene family in metazoans: insights from comparative genomics
-
Simionato E, Ledent V, Richards G, Thomas-Chollier M, Kerner P, et al. (2007) Origin and diversification of the basic helix-loop-helix gene family in metazoans: insights from comparative genomics. BMC Evol Biol 7: 33.
-
(2007)
BMC Evol Biol
, vol.7
, pp. 33
-
-
Simionato, E.1
Ledent, V.2
Richards, G.3
Thomas-Chollier, M.4
Kerner, P.5
-
10
-
-
67650594823
-
A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors
-
Grove CA, De Masi F, Barrasa MI, Newburger DE, Alkema MJ, et al. (2009) A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138: 314-327.
-
(2009)
Cell
, vol.138
, pp. 314-327
-
-
Grove, C.A.1
De Masi, F.2
Barrasa, M.I.3
Newburger, D.E.4
Alkema, M.J.5
-
11
-
-
34748922359
-
A C. elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration
-
Pickett CL, Breen KT, Ayer DE, (2007) A C. elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration. Dev Biol 310: 226-239.
-
(2007)
Dev Biol
, vol.310
, pp. 226-239
-
-
Pickett, C.L.1
Breen, K.T.2
Ayer, D.E.3
-
12
-
-
36248964713
-
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
-
Samuelson AV, Carr CE, Ruvkun G, (2007) Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants. Genes Dev 21: 2976-2994.
-
(2007)
Genes Dev
, vol.21
, pp. 2976-2994
-
-
Samuelson, A.V.1
Carr, C.E.2
Ruvkun, G.3
-
13
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
-
14
-
-
84865196738
-
Glucose sensing by ChREBP/MondoA-Mlx transcription factors
-
Havula E, Hietakangas V, (2012) Glucose sensing by ChREBP/MondoA-Mlx transcription factors. Semin Cell Dev Biol 23: 640-647.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 640-647
-
-
Havula, E.1
Hietakangas, V.2
-
15
-
-
47749120570
-
Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping
-
Iizuka K, Horikawa Y, (2008) Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping. Biochem Biophys Res Commun 374: 95-100.
-
(2008)
Biochem Biophys Res Commun
, vol.374
, pp. 95-100
-
-
Iizuka, K.1
Horikawa, Y.2
-
16
-
-
15744376705
-
Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes
-
Ma L, Tsatsos NG, Towle HC, (2005) Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes. J Biol Chem 280: 12019-12027.
-
(2005)
J Biol Chem
, vol.280
, pp. 12019-12027
-
-
Ma, L.1
Tsatsos, N.G.2
Towle, H.C.3
-
17
-
-
2442614148
-
Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes
-
Stoeckman AK, Ma L, Towle HC, (2004) Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes. J Biol Chem 279: 15662-15669.
-
(2004)
J Biol Chem
, vol.279
, pp. 15662-15669
-
-
Stoeckman, A.K.1
Ma, L.2
Towle, H.C.3
-
18
-
-
2442489891
-
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression
-
Dentin R, Pegorier JP, Benhamed F, Foufelle F, Ferre P, et al. (2004) Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem 279: 20314-20326.
-
(2004)
J Biol Chem
, vol.279
, pp. 20314-20326
-
-
Dentin, R.1
Pegorier, J.P.2
Benhamed, F.3
Foufelle, F.4
Ferre, P.5
-
19
-
-
8144229872
-
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription
-
Ishii S, Iizuka K, Miller BC, Uyeda K, (2004) Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc Natl Acad Sci U S A 101: 15597-15602.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15597-15602
-
-
Ishii, S.1
Iizuka, K.2
Miller, B.C.3
Uyeda, K.4
-
20
-
-
33746536677
-
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
-
Uyeda K, Repa JJ, (2006) Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab 4: 107-110.
-
(2006)
Cell Metab
, vol.4
, pp. 107-110
-
-
Uyeda, K.1
Repa, J.J.2
-
21
-
-
74849117906
-
Williams-Beuren syndrome
-
Pober BR, (2010) Williams-Beuren syndrome. N Engl J Med 362: 239-252.
-
(2010)
N Engl J Med
, vol.362
, pp. 239-252
-
-
Pober, B.R.1
-
22
-
-
84856041164
-
Evolution of the Max and Mlx networks in animals
-
McFerrin LG, Atchley WR, (2011) Evolution of the Max and Mlx networks in animals. Genome Biol Evol 3: 915-937.
-
(2011)
Genome Biol Evol
, vol.3
, pp. 915-937
-
-
McFerrin, L.G.1
Atchley, W.R.2
-
23
-
-
84878533962
-
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
-
O'Rourke EJ, Ruvkun G, (2013) MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Nat Cell Biol 15: 668-676.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 668-676
-
-
O'Rourke, E.J.1
Ruvkun, G.2
-
24
-
-
34848834757
-
A global analysis of genetic interactions in Caenorhabditis elegans
-
Byrne AB, Weirauch MT, Wong V, Koeva M, Dixon SJ, et al. (2007) A global analysis of genetic interactions in Caenorhabditis elegans. J Biol 6: 8.
-
(2007)
J Biol
, vol.6
, pp. 8
-
-
Byrne, A.B.1
Weirauch, M.T.2
Wong, V.3
Koeva, M.4
Dixon, S.J.5
-
25
-
-
0031685525
-
Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
-
Gems D, Sutton AJ, Sundermeyer ML, Albert PS, King KV, et al. (1998) Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150: 129-155.
-
(1998)
Genetics
, vol.150
, pp. 129-155
-
-
Gems, D.1
Sutton, A.J.2
Sundermeyer, M.L.3
Albert, P.S.4
King, K.V.5
-
26
-
-
0032573178
-
The genetics of caloric restriction in Caenorhabditis elegans
-
Lakowski B, Hekimi S, (1998) The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A 95: 13091-13096.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13091-13096
-
-
Lakowski, B.1
Hekimi, S.2
-
27
-
-
1642281181
-
eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx
-
McKay JP, Raizen DM, Gottschalk A, Schafer WR, Avery L, (2004) eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx. Genetics 166: 161-169.
-
(2004)
Genetics
, vol.166
, pp. 161-169
-
-
McKay, J.P.1
Raizen, D.M.2
Gottschalk, A.3
Schafer, W.R.4
Avery, L.5
-
28
-
-
48149109399
-
Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding
-
Greer ER, Pérez CL, Van Gilst MR, Lee BH, Ashrafi K, (2008) Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding. Cell Metab 8(2): 118-31.
-
(2008)
Cell Metab
, vol.8
, Issue.2
, pp. 118-131
-
-
Greer, E.R.1
Pérez, C.L.2
Van Gilst, M.R.3
Lee, B.H.4
Ashrafi, K.5
-
29
-
-
77957797819
-
TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance
-
Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT, (2010) TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance. Cell 143(2): 299-312.
-
(2010)
Cell
, vol.143
, Issue.2
, pp. 299-312
-
-
Luo, S.1
Kleemann, G.A.2
Ashraf, J.M.3
Shaw, W.M.4
Murphy, C.T.5
-
30
-
-
0026515348
-
Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans
-
Vowels JJ, Thomas JH, (1992) Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Genetics 130: 105-123.
-
(1992)
Genetics
, vol.130
, pp. 105-123
-
-
Vowels, J.J.1
Thomas, J.H.2
-
31
-
-
39649094910
-
Insulin, cGMP, and TGF-beta signals regulate food intake and quiescence in C. elegans: a model for satiety
-
You YJ, Kim J, Raizen DM, Avery L, (2008) Insulin, cGMP, and TGF-beta signals regulate food intake and quiescence in C. elegans: a model for satiety. Cell Metab 7: 249-257.
-
(2008)
Cell Metab
, vol.7
, pp. 249-257
-
-
You, Y.J.1
Kim, J.2
Raizen, D.M.3
Avery, L.4
-
32
-
-
34848868499
-
The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling
-
Shaw WM, Luo S, Landis J, Ashraf J, Murphy CT, (2007) The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. Current Biology 17(19): 1635-45.
-
(2007)
Current Biology
, vol.17
, Issue.19
, pp. 1635-1645
-
-
Shaw, W.M.1
Luo, S.2
Landis, J.3
Ashraf, J.4
Murphy, C.T.5
-
33
-
-
33744972290
-
A gene-centered C. elegans protein-DNA interaction network
-
Deplancke B, Mukhopadhyay A, Ao W, Elewa AM, Grove CA, et al. (2006) A gene-centered C. elegans protein-DNA interaction network. Cell 125: 1193-1205.
-
(2006)
Cell
, vol.125
, pp. 1193-1205
-
-
Deplancke, B.1
Mukhopadhyay, A.2
Ao, W.3
Elewa, A.M.4
Grove, C.A.5
-
34
-
-
0034462487
-
MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network
-
Billin AN, Eilers AL, Coulter KL, Logan JS, Ayer DE, (2000) MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network. Mol Cell Biol 20: 8845-8854.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8845-8854
-
-
Billin, A.N.1
Eilers, A.L.2
Coulter, K.L.3
Logan, J.S.4
Ayer, D.E.5
-
35
-
-
0035923516
-
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
-
Kawaguchi T, Takenoshita M, Kabashima T, Uyeda K, (2001) Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein. Proc Natl Acad Sci U S A 98: 13710-13715.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13710-13715
-
-
Kawaguchi, T.1
Takenoshita, M.2
Kabashima, T.3
Uyeda, K.4
-
36
-
-
67649292737
-
Unlocking the secrets of the genome
-
Celniker SE, Dillon LA, Gerstein MB, Gunsalus KC, Henikoff S, et al. (2009) Unlocking the secrets of the genome. Nature 459: 927-930.
-
(2009)
Nature
, vol.459
, pp. 927-930
-
-
Celniker, S.E.1
Dillon, L.A.2
Gerstein, M.B.3
Gunsalus, K.C.4
Henikoff, S.5
-
37
-
-
84881175076
-
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
-
Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, et al. (2013) PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell 154: 676-690.
-
(2013)
Cell
, vol.154
, pp. 676-690
-
-
Tepper, R.G.1
Ashraf, J.2
Kaletsky, R.3
Kleemann, G.4
Murphy, C.T.5
-
38
-
-
79551614016
-
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans
-
Niu W, Lu ZJ, Zhong M, Sarov M, Murray JI, et al. (2011) Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. Genome Res 21: 245-254.
-
(2011)
Genome Res
, vol.21
, pp. 245-254
-
-
Niu, W.1
Lu, Z.J.2
Zhong, M.3
Sarov, M.4
Murray, J.I.5
-
39
-
-
0037119951
-
Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1
-
Iritani BM, Delrow J, Grandori C, Gomez I, Klacking M, et al. (2002) Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1. EMBO J 21: 4820-4830.
-
(2002)
EMBO J
, vol.21
, pp. 4820-4830
-
-
Iritani, B.M.1
Delrow, J.2
Grandori, C.3
Gomez, I.4
Klacking, M.5
-
40
-
-
84860258657
-
MAD1 and its life as a MYC antagonist: an update
-
Luscher B, (2012) MAD1 and its life as a MYC antagonist: an update. Eur J Cell Biol 91: 506-514.
-
(2012)
Eur J Cell Biol
, vol.91
, pp. 506-514
-
-
Luscher, B.1
-
41
-
-
2442435802
-
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
-
Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K, (2004) Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc Natl Acad Sci U S A 101: 7281-7286.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7281-7286
-
-
Iizuka, K.1
Bruick, R.K.2
Liang, G.3
Horton, J.D.4
Uyeda, K.5
-
42
-
-
33947151464
-
The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions
-
Pedersen KB, Zhang P, Doumen C, Charbonnet M, Lu D, et al. (2007) The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions. Am J Physiol Endocrinol Metab 292: E788-801.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Pedersen, K.B.1
Zhang, P.2
Doumen, C.3
Charbonnet, M.4
Lu, D.5
-
43
-
-
0035846604
-
daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
-
Henderson ST, Johnson TE, (2001) daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 11: 1975-1980.
-
(2001)
Curr Biol
, vol.11
, pp. 1975-1980
-
-
Henderson, S.T.1
Johnson, T.E.2
-
44
-
-
48949119266
-
Dietary restriction by growth in axenic medium induces discrete changes in the transcriptional output of genes involved in energy metabolism in Caenorhabditis elegans
-
Castelein N, Hoogewijs D, De Vreese A, Braeckman BP, Vanfleteren JR, (2008) Dietary restriction by growth in axenic medium induces discrete changes in the transcriptional output of genes involved in energy metabolism in Caenorhabditis elegans. Biotechnol J 3: 803-812.
-
(2008)
Biotechnol J
, vol.3
, pp. 803-812
-
-
Castelein, N.1
Hoogewijs, D.2
De Vreese, A.3
Braeckman, B.P.4
Vanfleteren, J.R.5
-
45
-
-
80053385863
-
Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway
-
Gallo M, Park D, Riddle DL, (2011) Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway. Mech Ageing Dev 132: 515-518.
-
(2011)
Mech Ageing Dev
, vol.132
, pp. 515-518
-
-
Gallo, M.1
Park, D.2
Riddle, D.L.3
-
46
-
-
8344282655
-
The role of oxidative damage and stress in aging
-
Bokov A, Chaudhuri A, Richardson A, (2004) The role of oxidative damage and stress in aging. Mech Ageing Dev 125: 811-826.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 811-826
-
-
Bokov, A.1
Chaudhuri, A.2
Richardson, A.3
-
47
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto RI, (2008) Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev 22: 1427-1438.
-
(2008)
Genes Dev
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
48
-
-
84882887554
-
A cytoprotective perspective on longevity regulation
-
Shore DE, Ruvkun G, (2013) A cytoprotective perspective on longevity regulation. Trends Cell Biol 23: 409-420.
-
(2013)
Trends Cell Biol
, vol.23
, pp. 409-420
-
-
Shore, D.E.1
Ruvkun, G.2
-
49
-
-
0035082093
-
Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans
-
Barsyte D, Lovejoy DA, Lithgow GJ, (2001) Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. Faseb J 15: 627-634.
-
(2001)
Faseb J
, vol.15
, pp. 627-634
-
-
Barsyte, D.1
Lovejoy, D.A.2
Lithgow, G.J.3
-
50
-
-
0038047438
-
Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens
-
Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, et al. (2003) Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science 300: 1921.
-
(2003)
Science
, vol.300
, pp. 1921
-
-
Garsin, D.A.1
Villanueva, J.M.2
Begun, J.3
Kim, D.H.4
Sifri, C.D.5
-
51
-
-
0032782364
-
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
-
Honda Y, Honda S, (1999) The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. Faseb J 13: 1385-1393.
-
(1999)
Faseb J
, vol.13
, pp. 1385-1393
-
-
Honda, Y.1
Honda, S.2
-
52
-
-
12144264839
-
Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress
-
Epub 2004 Oct 2020
-
Lamitina ST, Strange K (2005) Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress. Am J Physiol Cell Physiol 288: C467-474. Epub 2004 Oct 2020.
-
(2005)
Am J Physiol Cell Physiol
, vol.288
, pp. 467-474
-
-
Lamitina, S.T.1
Strange, K.2
-
53
-
-
33751350245
-
Glyceraldehyde-3-phosphate dehydrogenase mediates anoxia response and survival in Caenorhabditis elegans
-
Mendenhall AR, LaRue B, Padilla PA (2006) Glyceraldehyde-3-phosphate dehydrogenase mediates anoxia response and survival in Caenorhabditis elegans. Genetics. pp. 1173-1187.
-
(2006)
Genetics
, pp. 1173-1187
-
-
Mendenhall, A.R.1
LaRue, B.2
Padilla, P.A.3
-
54
-
-
0030014296
-
A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
-
Murakami S, Johnson TE, (1996) A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. Genetics 143: 1207-1218.
-
(1996)
Genetics
, vol.143
, pp. 1207-1218
-
-
Murakami, S.1
Johnson, T.E.2
-
55
-
-
0036975161
-
Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans
-
Houthoofd K, Braeckman BP, Lenaerts I, Brys K, De Vreese A, et al. (2002) Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans. Exp Gerontol 37: 1371-1378.
-
(2002)
Exp Gerontol
, vol.37
, pp. 1371-1378
-
-
Houthoofd, K.1
Braeckman, B.P.2
Lenaerts, I.3
Brys, K.4
De Vreese, A.5
-
56
-
-
0034953956
-
Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans
-
Walker GA, White TM, McColl G, Jenkins NL, Babich S, et al. (2001) Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci 56: B281-287.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Walker, G.A.1
White, T.M.2
McColl, G.3
Jenkins, N.L.4
Babich, S.5
-
57
-
-
70349266064
-
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
-
Ben-Zvi A, Miller EA, Morimoto RI (2009) Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci USA. pp. 14914-14919.
-
(2009)
Proc Natl Acad Sci USA
, pp. 14914-14919
-
-
Ben-Zvi, A.1
Miller, E.A.2
Morimoto, R.I.3
-
58
-
-
0034705224
-
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans
-
Satyal SH, Schmidt E, Kitagawa K, Sondheimer N, Lindquist S, et al. (2000) Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. Proc Natl Acad Sci USA 97(11): 5750-5.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.11
, pp. 5750-5755
-
-
Satyal, S.H.1
Schmidt, E.2
Kitagawa, K.3
Sondheimer, N.4
Lindquist, S.5
-
59
-
-
0036678146
-
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
-
Morley JF, Brignull HR, Weyers JJ, Morimoto RI, (2002) The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Proc Natl Acad Sci USA 99(16): 10417-22.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.16
, pp. 10417-10422
-
-
Morley, J.F.1
Brignull, H.R.2
Weyers, J.J.3
Morimoto, R.I.4
-
60
-
-
0036678146
-
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
-
Morley JF, Brignull HR, Weyers JJ, Morimoto RI, (2002) The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Proc Natl Acad Sci U S A 99: 10417-10422.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10417-10422
-
-
Morley, J.F.1
Brignull, H.R.2
Weyers, J.J.3
Morimoto, R.I.4
-
61
-
-
84856338151
-
Regulation of gene transcription by the oncoprotein MYC
-
Luscher B, Vervoorts J, (2012) Regulation of gene transcription by the oncoprotein MYC. Gene 494: 145-160.
-
(2012)
Gene
, vol.494
, pp. 145-160
-
-
Luscher, B.1
Vervoorts, J.2
-
62
-
-
79959694931
-
An extended Myc network contributes to glucose homeostasis in cancer and diabetes
-
Peterson CW, Ayer DE, (2011) An extended Myc network contributes to glucose homeostasis in cancer and diabetes. Front Biosci (Landmark Ed) 16: 2206-2223.
-
(2011)
Front Biosci (Landmark Ed)
, vol.16
, pp. 2206-2223
-
-
Peterson, C.W.1
Ayer, D.E.2
-
63
-
-
34047185326
-
Mnt takes control as key regulator of the myc/max/mxd network
-
Wahlstrom T, Henriksson M, (2007) Mnt takes control as key regulator of the myc/max/mxd network. Adv Cancer Res 97: 61-80.
-
(2007)
Adv Cancer Res
, vol.97
, pp. 61-80
-
-
Wahlstrom, T.1
Henriksson, M.2
-
64
-
-
33144473916
-
The Mlx network: evidence for a parallel Max-like transcriptional network that regulates energy metabolism
-
Billin AN, Ayer DE, (2006) The Mlx network: evidence for a parallel Max-like transcriptional network that regulates energy metabolism. Curr Top Microbiol Immunol 302: 255-278.
-
(2006)
Curr Top Microbiol Immunol
, vol.302
, pp. 255-278
-
-
Billin, A.N.1
Ayer, D.E.2
-
65
-
-
84867040616
-
Mitochondrial SKN-1/Nrf mediates a conserved starvation response
-
Paek J, Lo JY, Narasimhan SD, Nguyen TN, Glover-Cutter K, et al. (2012) Mitochondrial SKN-1/Nrf mediates a conserved starvation response. Cell Metab 16: 526-537.
-
(2012)
Cell Metab
, vol.16
, pp. 526-537
-
-
Paek, J.1
Lo, J.Y.2
Narasimhan, S.D.3
Nguyen, T.N.4
Glover-Cutter, K.5
-
66
-
-
35649014840
-
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
-
Kim JW, Gao P, Liu YC, Semenza GL, Dang CV, (2007) Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol Cell Biol 27: 7381-7393.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7381-7393
-
-
Kim, J.W.1
Gao, P.2
Liu, Y.C.3
Semenza, G.L.4
Dang, C.V.5
-
67
-
-
2942701935
-
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays
-
Kim JW, Zeller KI, Wang Y, Jegga AG, Aronow BJ, et al. (2004) Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol Cell Biol 24: 5923-5936.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5923-5936
-
-
Kim, J.W.1
Zeller, K.I.2
Wang, Y.3
Jegga, A.G.4
Aronow, B.J.5
-
68
-
-
0030794277
-
Identification of putative c-Myc-responsive genes: characterization of rcl, a novel growth-related gene
-
Lewis BC, Shim H, Li Q, Wu CS, Lee LA, et al. (1997) Identification of putative c-Myc-responsive genes: characterization of rcl, a novel growth-related gene. Mol Cell Biol 17: 4967-4978.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4967-4978
-
-
Lewis, B.C.1
Shim, H.2
Li, Q.3
Wu, C.S.4
Lee, L.A.5
-
69
-
-
0034698178
-
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
-
Osthus RC, Shim H, Kim S, Li Q, Reddy R, et al. (2000) Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. J Biol Chem 275: 21797-21800.
-
(2000)
J Biol Chem
, vol.275
, pp. 21797-21800
-
-
Osthus, R.C.1
Shim, H.2
Kim, S.3
Li, Q.4
Reddy, R.5
-
70
-
-
0030921103
-
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth
-
Shim H, Dolde C, Lewis BC, Wu CS, Dang G, et al. (1997) c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc Natl Acad Sci U S A 94: 6658-6663.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
Wu, C.S.4
Dang, G.5
-
71
-
-
33845187907
-
Global mapping of c-Myc binding sites and target gene networks in human B cells
-
Zeller KI, Zhao X, Lee CW, Chiu KP, Yao F, et al. (2006) Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A 103: 17834-17839.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17834-17839
-
-
Zeller, K.I.1
Zhao, X.2
Lee, C.W.3
Chiu, K.P.4
Yao, F.5
-
72
-
-
79952851120
-
Myc, mondo, and metabolism
-
Sloan EJ, Ayer DE, (2010) Myc, mondo, and metabolism. Genes Cancer 1: 587-596.
-
(2010)
Genes Cancer
, vol.1
, pp. 587-596
-
-
Sloan, E.J.1
Ayer, D.E.2
-
73
-
-
84859921736
-
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
-
Herman MA, Peroni OD, Villoria J, Schon MR, Abumrad NA, et al. (2012) A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature 484: 333-338.
-
(2012)
Nature
, vol.484
, pp. 333-338
-
-
Herman, M.A.1
Peroni, O.D.2
Villoria, J.3
Schon, M.R.4
Abumrad, N.A.5
-
74
-
-
2942559261
-
Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells
-
Grinberg AV, Hu CD, Kerppola TK, (2004) Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells. Mol Cell Biol 24: 4294-4308.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4294-4308
-
-
Grinberg, A.V.1
Hu, C.D.2
Kerppola, T.K.3
-
75
-
-
0035797475
-
Dynamic in vivo interactions among Myc network members
-
Yin X, Landay MF, Han W, Levitan ES, Watkins SC, et al. (2001) Dynamic in vivo interactions among Myc network members. Oncogene 20: 4650-4664.
-
(2001)
Oncogene
, vol.20
, pp. 4650-4664
-
-
Yin, X.1
Landay, M.F.2
Han, W.3
Levitan, E.S.4
Watkins, S.C.5
-
76
-
-
41149099640
-
Regulation of the MAD1 promoter by G-CSF
-
Jiang K, Hein N, Eckert K, Luscher-Firzlaff J, Luscher B, (2008) Regulation of the MAD1 promoter by G-CSF. Nucleic Acids Res 36: 1517-1531.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1517-1531
-
-
Jiang, K.1
Hein, N.2
Eckert, K.3
Luscher-Firzlaff, J.4
Luscher, B.5
-
77
-
-
7244238167
-
Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
-
Epub 42004 Aug 44511
-
McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D (2004) Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J Biol Chem 279: 44533-44543. Epub 42004 Aug 44511.
-
(2004)
J Biol Chem
, vol.279
, pp. 44533-44543
-
-
McElwee, J.J.1
Schuster, E.2
Blanc, E.3
Thomas, J.H.4
Gems, D.5
-
78
-
-
84867010006
-
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie Z, Hu G, Wei G, Cui K, Yamane A, et al. (2012) c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 151: 68-79.
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
-
79
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin CY, Loven J, Rahl PB, Paranal RM, Burge CB, et al. (2012) Transcriptional amplification in tumor cells with elevated c-Myc. Cell 151: 56-67.
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
Paranal, R.M.4
Burge, C.B.5
-
80
-
-
84878518534
-
Recent progress on the role of ChREBP in glucose and lipid metabolism
-
Iizuka K, (2013) Recent progress on the role of ChREBP in glucose and lipid metabolism. Endocr J 60: 543-555.
-
(2013)
Endocr J
, vol.60
, pp. 543-555
-
-
Iizuka, K.1
-
81
-
-
77149171951
-
A metabolic signature of long life in Caenorhabditis elegans
-
Fuchs S, Bundy JG, Davies SK, Viney JM, Swire JS, et al. (2010) A metabolic signature of long life in Caenorhabditis elegans. BMC Biol 8: 14.
-
(2010)
BMC Biol
, vol.8
, pp. 14
-
-
Fuchs, S.1
Bundy, J.G.2
Davies, S.K.3
Viney, J.M.4
Swire, J.S.5
-
82
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch WE, Morimoto RI, Dillin A, Kelly JW, (2008) Adapting proteostasis for disease intervention. Science 319(5865): 916-9.
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
83
-
-
34247569105
-
Lifespan regulation by evolutionarily conserved genes essential for viability
-
Curran SP, Ruvkun G, (2007) Lifespan regulation by evolutionarily conserved genes essential for viability. PLoS Genet 3: e56.
-
(2007)
PLoS Genet
, vol.3
-
-
Curran, S.P.1
Ruvkun, G.2
-
84
-
-
67649491263
-
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
-
Curran SP, Wu X, Riedel CG, Ruvkun G, (2009) A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. Nature 459: 1079-1084.
-
(2009)
Nature
, vol.459
, pp. 1079-1084
-
-
Curran, S.P.1
Wu, X.2
Riedel, C.G.3
Ruvkun, G.4
-
85
-
-
77953091249
-
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
-
Henis-Korenblit S, Zhang P, Hansen M, McCormick M, Lee SJ, et al. (2010) Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc Natl Acad Sci U S A 107: 9730-9735.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9730-9735
-
-
Henis-Korenblit, S.1
Zhang, P.2
Hansen, M.3
McCormick, M.4
Lee, S.J.5
-
86
-
-
21144460742
-
Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression
-
Halaschek-Wiener J, Khattra JS, McKay S, Pouzyrev A, Stott JM, et al. (2005) Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Genome Res 15: 603-615.
-
(2005)
Genome Res
, vol.15
, pp. 603-615
-
-
Halaschek-Wiener, J.1
Khattra, J.S.2
McKay, S.3
Pouzyrev, A.4
Stott, J.M.5
-
87
-
-
84901377818
-
Molecular Neurodegeneration. Mol Neurodegener
-
doi: 10.1186/1750-1326-4-39
-
Zhao J, Li L, Leissring M, (2009) Molecular Neurodegeneration. Mol Neurodegener. 4: 39 doi:10.1186/1750-1326-4-39.
-
(2009)
, vol.4
, pp. 39
-
-
Zhao, J.1
Li, L.2
Leissring, M.3
-
88
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu AL, Murphy CT, Kenyon C, (2003) Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300: 1142-1145.
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
89
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
90
-
-
37749003575
-
Vector-free DNA constructs improve transgene expression in C. elegans
-
Etchberger JF, Hobert O, (2008) Vector-free DNA constructs improve transgene expression in C. elegans. Nat Methods 5: 3.
-
(2008)
Nat Methods
, vol.5
, pp. 3
-
-
Etchberger, J.F.1
Hobert, O.2
|