A cytoprotective perspective on longevity regulation

Trends in Cell Biology

Volumn 23, Issue 9, 2013, Pages 409-420

  Shore, David E ^a,b   Ruvkun, Gary ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aging; Cytoprotection; Detoxification; Hormesis; Longevity; Stress

Indexed keywords

CATALASE; CHAPERONIN 60; COPPER ZINC SUPEROXIDE DISMUTASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUTATHIONE TRANSFERASE; INITIATION FACTOR 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; TRANSFORMING GROWTH FACTOR BETA; URIDINE DIPHOSPHATE; INSULIN;

3' UNTRANSLATED REGION; AGING; AUTOPHAGOSOME; AUTOPHAGY; AVERSIVE BEHAVIOR; CAENORHABDITIS ELEGANS; CELL FUNCTION; CELL PROTECTION; CYTOSKELETON; DETOXIFICATION; DROSOPHILA MELANOGASTER; ENDOPLASMIC RETICULUM; GENE INACTIVATION; GENE MUTATION; GENETIC TRANSCRIPTION; HEAT STRESS; HEAT TOLERANCE; HUMAN; INNATE IMMUNITY; LIFE EXTENSION; LONGEVITY; NONHUMAN; OPEN READING FRAME; OSMOTIC STRESS; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN HOMEOSTASIS; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION INITIATION; ULTRAVIOLET RADIATION; UNFOLDED PROTEIN RESPONSE; XENOBIOTIC METABOLISM; XENOBIOTIC STRESS; ANIMAL; DRUG DETOXIFICATION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEOSTASIS DEFICIENCY;

CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; IMMUNITY, INNATE; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; METABOLIC DETOXICATION, PHASE I; OXIDATIVE STRESS; PROTEOSTASIS DEFICIENCIES; SIGNAL TRANSDUCTION;

EID: 84882887554     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2013.04.007     Document Type: Review

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