-
1
-
-
79959559899
-
Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
-
N. Alic, T.D. Andrews, M.E. Giannakou, I. Papatheodorou, C. Slack, M.P. Hoddinott, H.M. Cochemé, E.F. Schuster, J.M. Thornton, and L. Partridge Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling Mol. Syst. Biol. 7 2011 502
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 502
-
-
Alic, N.1
Andrews, T.D.2
Giannakou, M.E.3
Papatheodorou, I.4
Slack, C.5
Hoddinott, M.P.6
Cochemé, H.M.7
Schuster, E.F.8
Thornton, J.M.9
Partridge, L.10
-
2
-
-
33744976074
-
C elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span
-
A. Berdichevsky, M. Viswanathan, H.R. Horvitz, and L. Guarente C elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span Cell 125 2006 1165 1177
-
(2006)
Cell
, vol.125
, pp. 1165-1177
-
-
Berdichevsky, A.1
Viswanathan, M.2
Horvitz, H.R.3
Guarente, L.4
-
3
-
-
52349095482
-
Inferring condition-specific modulation of transcription factor activity in yeast through regulon-based analysis of genomewide expression
-
A. Boorsma, X.J. Lu, A. Zakrzewska, F.M. Klis, and H.J. Bussemaker Inferring condition-specific modulation of transcription factor activity in yeast through regulon-based analysis of genomewide expression PLoS ONE 3 2008 e3112
-
(2008)
PLoS ONE
, vol.3
, pp. 3112
-
-
Boorsma, A.1
Lu, X.J.2
Zakrzewska, A.3
Klis, F.M.4
Bussemaker, H.J.5
-
4
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71 94
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
5
-
-
47549100826
-
An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C elegans
-
Y.V. Budovskaya, K. Wu, L.K. Southworth, M. Jiang, P. Tedesco, T.E. Johnson, and S.K. Kim An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C elegans Cell 134 2008 291 303
-
(2008)
Cell
, vol.134
, pp. 291-303
-
-
Budovskaya, Y.V.1
Wu, K.2
Southworth, L.K.3
Jiang, M.4
Tedesco, P.5
Johnson, T.E.6
Kim, S.K.7
-
7
-
-
67650895858
-
Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans
-
M.D. Chikina, C. Huttenhower, C.T. Murphy, and O.G. Troyanskaya Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans PLoS Comput. Biol. 5 2009 e1000417
-
(2009)
PLoS Comput. Biol.
, vol.5
, pp. 1000417
-
-
Chikina, M.D.1
Huttenhower, C.2
Murphy, C.T.3
Troyanskaya, O.G.4
-
8
-
-
0037174629
-
Timing requirements for insulin/IGF-1 signaling in C elegans
-
A. Dillin, D.K. Crawford, and C. Kenyon Timing requirements for insulin/IGF-1 signaling in C elegans Science 298 2002 830 834
-
(2002)
Science
, vol.298
, pp. 830-834
-
-
Dillin, A.1
Crawford, D.K.2
Kenyon, C.3
-
9
-
-
34547810054
-
Quantitative mass spectrometry identifies insulin signaling targets in C elegans
-
M.Q. Dong, J.D. Venable, N. Au, T. Xu, S.K. Park, D. Cociorva, J.R. Johnson, A. Dillin, and J.R. Yates 3rd Quantitative mass spectrometry identifies insulin signaling targets in C elegans Science 317 2007 660 663
-
(2007)
Science
, vol.317
, pp. 660-663
-
-
Dong, M.Q.1
Venable, J.D.2
Au, N.3
Xu, T.4
Park, S.K.5
Cociorva, D.6
Johnson, J.R.7
Dillin, A.8
Yates III, J.R.9
-
10
-
-
33748191291
-
Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE
-
B.C. Foat, A.V. Morozov, and H.J. Bussemaker Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE Bioinformatics 22 2006 e141 e149
-
(2006)
Bioinformatics
, vol.22
-
-
Foat, B.C.1
Morozov, A.V.2
Bussemaker, H.J.3
-
11
-
-
0034676457
-
Functional genomic analysis of C elegans chromosome i by systematic RNA interference
-
A.G. Fraser, R.S. Kamath, P. Zipperlen, M. Martinez-Campos, M. Sohrmann, and J. Ahringer Functional genomic analysis of C elegans chromosome I by systematic RNA interference Nature 408 2000 325 330
-
(2000)
Nature
, vol.408
, pp. 325-330
-
-
Fraser, A.G.1
Kamath, R.S.2
Zipperlen, P.3
Martinez-Campos, M.4
Sohrmann, M.5
Ahringer, J.6
-
12
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
-
T. Furuyama, T. Nakazawa, I. Nakano, and N. Mori Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues Biochem. J. 349 2000 629 634
-
(2000)
Biochem. J.
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
13
-
-
21144460742
-
Analysis of long-lived C elegans daf-2 mutants using serial analysis of gene expression
-
J. Halaschek-Wiener, J.S. Khattra, S. McKay, A. Pouzyrev, J.M. Stott, G.S. Yang, R.A. Holt, S.J. Jones, M.A. Marra, A.R. Brooks-Wilson, and D.L. Riddle Analysis of long-lived C elegans daf-2 mutants using serial analysis of gene expression Genome Res. 15 2005 603 615
-
(2005)
Genome Res.
, vol.15
, pp. 603-615
-
-
Halaschek-Wiener, J.1
Khattra, J.S.2
McKay, S.3
Pouzyrev, A.4
Stott, J.M.5
Yang, G.S.6
Holt, R.A.7
Jones, S.J.8
Marra, M.A.9
Brooks-Wilson, A.R.10
Riddle, D.L.11
-
14
-
-
0035846604
-
Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
-
S.T. Henderson, and T.E. Johnson daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans Curr. Biol. 11 2001 1975 1980
-
(2001)
Curr. Biol.
, vol.11
, pp. 1975-1980
-
-
Henderson, S.T.1
Johnson, T.E.2
-
15
-
-
11144355021
-
C elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
-
M. Hertweck, C. Göbel, and R. Baumeister C elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span Dev. Cell 6 2004 577 588
-
(2004)
Dev. Cell
, vol.6
, pp. 577-588
-
-
Hertweck, M.1
Göbel, C.2
Baumeister, R.3
-
16
-
-
0032782364
-
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
-
Y. Honda, and S. Honda The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans FASEB J. 13 1999 1385 1393
-
(1999)
FASEB J.
, vol.13
, pp. 1385-1393
-
-
Honda, Y.1
Honda, S.2
-
17
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
A.L. Hsu, C.T. Murphy, and C. Kenyon Regulation of aging and age-related disease by DAF-16 and heat-shock factor Science 300 2003 1142 1145
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
18
-
-
77955663602
-
Apigenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation
-
I. Kawasaki, M.H. Jeong, B.K. Oh, and Y.H. Shim Apigenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation FEBS Lett. 584 2010 3587 3591
-
(2010)
FEBS Lett.
, vol.584
, pp. 3587-3591
-
-
Kawasaki, I.1
Jeong, M.H.2
Oh, B.K.3
Shim, Y.H.4
-
19
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
C. Kenyon The plasticity of aging: insights from long-lived mutants Cell 120 2005 449 460
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
20
-
-
33645420945
-
Enrichment of regulatory motifs upstream of predicted DAF-16 targets
-
author reply 398
-
C. Kenyon, and C.T. Murphy Enrichment of regulatory motifs upstream of predicted DAF-16 targets Nat. Genet. 38 2006 397 398 author reply 398
-
(2006)
Nat. Genet.
, vol.38
, pp. 397-398
-
-
Kenyon, C.1
Murphy, C.T.2
-
21
-
-
0027771804
-
A C elegans mutant that lives twice as long as wild type
-
C. Kenyon, J. Chang, E. Gensch, A. Rudner, and R. Tabtiang A C elegans mutant that lives twice as long as wild type Nature 366 1993 461 464
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
23
-
-
0037466652
-
DAF-16 target genes that control C elegans life-span and metabolism
-
S.S. Lee, S. Kennedy, A.C. Tolonen, and G. Ruvkun DAF-16 target genes that control C elegans life-span and metabolism Science 300 2003 644 647
-
(2003)
Science
, vol.300
, pp. 644-647
-
-
Lee, S.S.1
Kennedy, S.2
Tolonen, A.C.3
Ruvkun, G.4
-
24
-
-
0345447590
-
Tissue-specific activities of C elegans DAF-16 in the regulation of lifespan
-
N. Libina, J.R. Berman, and C. Kenyon Tissue-specific activities of C elegans DAF-16 in the regulation of lifespan Cell 115 2003 489 502
-
(2003)
Cell
, vol.115
, pp. 489-502
-
-
Libina, N.1
Berman, J.R.2
Kenyon, C.3
-
25
-
-
0030657540
-
Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
K. Lin, J.B. Dorman, A. Rodan, and C. Kenyon daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans Science 278 1997 1319 1322
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
26
-
-
0034967720
-
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
-
K. Lin, H. Hsin, N. Libina, and C. Kenyon Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling Nat. Genet. 28 2001 139 145
-
(2001)
Nat. Genet.
, vol.28
, pp. 139-145
-
-
Lin, K.1
Hsin, H.2
Libina, N.3
Kenyon, C.4
-
27
-
-
0042631524
-
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
-
J. McElwee, K. Bubb, and J.H. Thomas Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16 Aging Cell 2 2003 111 121
-
(2003)
Aging Cell
, vol.2
, pp. 111-121
-
-
McElwee, J.1
Bubb, K.2
Thomas, J.H.3
-
28
-
-
7244238167
-
Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
-
J.J. McElwee, E. Schuster, E. Blanc, J.H. Thomas, and D. Gems Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance J. Biol. Chem. 279 2004 44533 44543
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44533-44543
-
-
McElwee, J.J.1
Schuster, E.2
Blanc, E.3
Thomas, J.H.4
Gems, D.5
-
29
-
-
33751430460
-
The search for DAF-16/FOXO transcriptional targets: Approaches and discoveries
-
C.T. Murphy The search for DAF-16/FOXO transcriptional targets: approaches and discoveries Exp. Gerontol. 41 2006 910 921
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 910-921
-
-
Murphy, C.T.1
-
30
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
C.T. Murphy, S.A. McCarroll, C.I. Bargmann, A. Fraser, R.S. Kamath, J. Ahringer, H. Li, and C. Kenyon Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans Nature 424 2003 277 283
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
31
-
-
79551614016
-
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C elegans
-
W. Niu, Z.J. Lu, M. Zhong, M. Sarov, J.I. Murray, C.M. Brdlik, J. Janette, C. Chen, P. Alves, and E. Preston Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C elegans Genome Res. 21 2011 245 254
-
(2011)
Genome Res.
, vol.21
, pp. 245-254
-
-
Niu, W.1
Lu, Z.J.2
Zhong, M.3
Sarov, M.4
Murray, J.I.5
Brdlik, C.M.6
Janette, J.7
Chen, C.8
Alves, P.9
Preston, E.10
-
32
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C elegans
-
S. Ogg, S. Paradis, S. Gottlieb, G.I. Patterson, L. Lee, H.A. Tissenbaum, and G. Ruvkun The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C elegans Nature 389 1997 994 999
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
33
-
-
31744438846
-
Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
-
S.W. Oh, A. Mukhopadhyay, B.L. Dixit, T. Raha, M.R. Green, and H.A. Tissenbaum Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation Nat. Genet. 38 2006 251 257
-
(2006)
Nat. Genet.
, vol.38
, pp. 251-257
-
-
Oh, S.W.1
Mukhopadhyay, A.2
Dixit, B.L.3
Raha, T.4
Green, M.R.5
Tissenbaum, H.A.6
-
34
-
-
34249888736
-
PHA-4/Foxa mediates diet-restriction-induced longevity of C elegans
-
S.H. Panowski, S. Wolff, H. Aguilaniu, J. Durieux, and A. Dillin PHA-4/Foxa mediates diet-restriction-induced longevity of C elegans Nature 447 2007 550 555
-
(2007)
Nature
, vol.447
, pp. 550-555
-
-
Panowski, S.H.1
Wolff, S.2
Aguilaniu, H.3
Durieux, J.4
Dillin, A.5
-
35
-
-
33846964132
-
Insight into transcription factor gene duplication from Caenorhabditis elegans Promoterome-driven expression patterns
-
J.S. Reece-Hoyes, J. Shingles, D. Dupuy, C.A. Grove, A.J. Walhout, M. Vidal, and I.A. Hope Insight into transcription factor gene duplication from Caenorhabditis elegans Promoterome-driven expression patterns BMC Genomics 8 2007 27
-
(2007)
BMC Genomics
, vol.8
, pp. 27
-
-
Reece-Hoyes, J.S.1
Shingles, J.2
Dupuy, D.3
Grove, C.A.4
Walhout, A.J.5
Vidal, M.6
Hope, I.A.7
-
36
-
-
77955643991
-
DamID in C elegans reveals longevity-associated targets of DAF-16/FoxO
-
E. Schuster, J.J. McElwee, J.M. Tullet, R. Doonan, F. Matthijssens, J.S. Reece-Hoyes, I.A. Hope, J.R. Vanfleteren, J.M. Thornton, and D. Gems DamID in C elegans reveals longevity-associated targets of DAF-16/FoxO Mol. Syst. Biol. 6 2010 399
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 399
-
-
Schuster, E.1
McElwee, J.J.2
Tullet, J.M.3
Doonan, R.4
Matthijssens, F.5
Reece-Hoyes, J.S.6
Hope, I.A.7
Vanfleteren, J.R.8
Thornton, J.M.9
Gems, D.10
-
37
-
-
33749014641
-
A conserved role for a GATA transcription factor in regulating epithelial innate immune responses
-
M. Shapira, B.J. Hamlin, J. Rong, K. Chen, M. Ronen, and M.W. Tan A conserved role for a GATA transcription factor in regulating epithelial innate immune responses Proc. Natl. Acad. Sci. USA 103 2006 14086 14091
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14086-14091
-
-
Shapira, M.1
Hamlin, B.J.2
Rong, J.3
Chen, K.4
Ronen, M.5
Tan, M.W.6
-
38
-
-
34848868499
-
The C elegans TGF-beta Dauer pathway regulates longevity via insulin signaling
-
W.M. Shaw, S. Luo, J. Landis, J. Ashraf, and C.T. Murphy The C elegans TGF-beta Dauer pathway regulates longevity via insulin signaling Curr. Biol. 17 2007 1635 1645
-
(2007)
Curr. Biol.
, vol.17
, pp. 1635-1645
-
-
Shaw, W.M.1
Luo, S.2
Landis, J.3
Ashraf, J.4
Murphy, C.T.5
-
39
-
-
84866753205
-
The BTB-ZF transcription factors
-
O.M. Siggs, and B. Beutler The BTB-ZF transcription factors Cell Cycle 11 2012 3358 3369
-
(2012)
Cell Cycle
, vol.11
, pp. 3358-3369
-
-
Siggs, O.M.1
Beutler, B.2
-
40
-
-
0032053198
-
Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display
-
W.N. Tawe, M.L. Eschbach, R.D. Walter, and K. Henkle-Dührsen Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display Nucleic Acids Res. 26 1998 1621 1627
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1621-1627
-
-
Tawe, W.N.1
Eschbach, M.L.2
Walter, R.D.3
Henkle-Dührsen, K.4
-
41
-
-
84856228489
-
Re-evaluating the role of ELT-3 in a GATA transcription factor circuit proposed to guide aging in C elegans
-
T. Tonsaker, R.M. Pratt, and J.D. McGhee Re-evaluating the role of ELT-3 in a GATA transcription factor circuit proposed to guide aging in C elegans Mech. Ageing Dev. 133 2012 50 53
-
(2012)
Mech. Ageing Dev.
, vol.133
, pp. 50-53
-
-
Tonsaker, T.1
Pratt, R.M.2
McGhee, J.D.3
-
42
-
-
33751382748
-
P38 MAPK regulates expression of immune response genes and contributes to longevity in C elegans
-
E.R. Troemel, S.W. Chu, V. Reinke, S.S. Lee, F.M. Ausubel, and D.H. Kim p38 MAPK regulates expression of immune response genes and contributes to longevity in C elegans PLoS Genet. 2 2006 e183
-
(2006)
PLoS Genet.
, vol.2
, pp. 183
-
-
Troemel, E.R.1
Chu, S.W.2
Reinke, V.3
Lee, S.S.4
Ausubel, F.M.5
Kim, D.H.6
-
43
-
-
33644750381
-
SMK-1, an essential regulator of DAF-16-mediated longevity
-
S. Wolff, H. Ma, D. Burch, G.A. Maciel, T. Hunter, and A. Dillin SMK-1, an essential regulator of DAF-16-mediated longevity Cell 124 2006 1039 1053
-
(2006)
Cell
, vol.124
, pp. 1039-1053
-
-
Wolff, S.1
Ma, H.2
Burch, D.3
Maciel, G.A.4
Hunter, T.5
Dillin, A.6
-
44
-
-
80051699717
-
OASIS: Online application for the survival analysis of lifespan assays performed in aging research
-
J.S. Yang, H.J. Nam, M. Seo, S.K. Han, Y. Choi, H.G. Nam, S.J. Lee, and S. Kim OASIS: online application for the survival analysis of lifespan assays performed in aging research PLoS ONE 6 2011 e23525
-
(2011)
PLoS ONE
, vol.6
, pp. 23525
-
-
Yang, J.S.1
Nam, H.J.2
Seo, M.3
Han, S.K.4
Choi, Y.5
Nam, H.G.6
Lee, S.J.7
Kim, S.8
-
45
-
-
84872143888
-
Direct and indirect gene regulation by a life-extending FOXO protein in C elegans: Roles for GATA factors and lipid gene regulators
-
P. Zhang, M. Judy, S.J. Lee, and C. Kenyon Direct and indirect gene regulation by a life-extending FOXO protein in C elegans: roles for GATA factors and lipid gene regulators Cell Metab. 17 2013 85 100
-
(2013)
Cell Metab.
, vol.17
, pp. 85-100
-
-
Zhang, P.1
Judy, M.2
Lee, S.J.3
Kenyon, C.4
-
46
-
-
79960610118
-
REVIGO summarizes and visualizes long lists of gene ontology terms
-
F. Supek, M. Bošnjak, N. Škunca, and T. Šmuc REVIGO summarizes and visualizes long lists of gene ontology terms PLoS ONE 6 2011 e21800
-
(2011)
PLoS ONE
, vol.6
, pp. 21800
-
-
Supek, F.1
Bošnjak, M.2
Škunca, N.3
Šmuc, T.4
|