메뉴 건너뛰기




Volumn 91, Issue 6-7, 2012, Pages 506-514

MAD1 and its life as a MYC antagonist: An update

Author keywords

Apoptosis; Chromatin; Cytokine; G CSF; Gene expression; Phosphorylation; Proliferation; TGF ; Tumor formation; Ubiquitination

Indexed keywords

HETERODIMER; MAX PROTEIN; MYC PROTEIN; PROTEIN MAD1;

EID: 84860258657     PISSN: 01719335     EISSN: 16181298     Source Type: Journal    
DOI: 10.1016/j.ejcb.2011.07.005     Document Type: Short Survey
Times cited : (33)

References (102)
  • 1
    • 58149343603 scopus 로고    scopus 로고
    • Evidence for activation of the TGF-beta1 promoter by C/EBPbeta and its modulation by Smads
    • Abraham S., Sweet T., Khalili K., Sawaya B.E., Amini S. Evidence for activation of the TGF-beta1 promoter by C/EBPbeta and its modulation by Smads. J. Interferon Cytokine Res. 2009, 29:1-7.
    • (2009) J. Interferon Cytokine Res. , vol.29 , pp. 1-7
    • Abraham, S.1    Sweet, T.2    Khalili, K.3    Sawaya, B.E.4    Amini, S.5
  • 2
    • 57349150176 scopus 로고    scopus 로고
    • Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest
    • Acosta J.C., Ferrandiz N., Bretones G., Torrano V., Blanco R., Richard C., O'Connell B., Sedivy J., Delgado M.D., Leon J. Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest. Mol. Cell. Biol. 2008, 28:7286-7295.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 7286-7295
    • Acosta, J.C.1    Ferrandiz, N.2    Bretones, G.3    Torrano, V.4    Blanco, R.5    Richard, C.6    O'Connell, B.7    Sedivy, J.8    Delgado, M.D.9    Leon, J.10
  • 3
    • 0027431276 scopus 로고
    • A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation
    • Ayer D.E., Eisenman R.N. A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. Genes Dev. 1993, 7:2110-2119.
    • (1993) Genes Dev. , vol.7 , pp. 2110-2119
    • Ayer, D.E.1    Eisenman, R.N.2
  • 4
    • 0027408096 scopus 로고
    • Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity
    • Ayer D.E., Kretzner L., Eisenman R.N. Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell 1993, 72:211-222.
    • (1993) Cell , vol.72 , pp. 211-222
    • Ayer, D.E.1    Kretzner, L.2    Eisenman, R.N.3
  • 5
    • 0028905563 scopus 로고
    • Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
    • Ayer D.E., Lawrence Q.A., Eisenman R.N. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 1995, 80:767-776.
    • (1995) Cell , vol.80 , pp. 767-776
    • Ayer, D.E.1    Lawrence, Q.A.2    Eisenman, R.N.3
  • 6
    • 77955949060 scopus 로고    scopus 로고
    • BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis
    • Basso K., Dalla-Favera R. BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis. Adv. Immunol. 2010, 105:193-210.
    • (2010) Adv. Immunol. , vol.105 , pp. 193-210
    • Basso, K.1    Dalla-Favera, R.2
  • 8
    • 0030986411 scopus 로고    scopus 로고
    • Repression of c-Myc responsive genes in cycling cells causes G1 arrest through reduction of cyclin E/CDK2 kinase activity
    • Berns K., Hijmans E.M., Bernards R. Repression of c-Myc responsive genes in cycling cells causes G1 arrest through reduction of cyclin E/CDK2 kinase activity. Oncogene 1997, 15:1347-1356.
    • (1997) Oncogene , vol.15 , pp. 1347-1356
    • Berns, K.1    Hijmans, E.M.2    Bernards, R.3
  • 9
    • 0033579566 scopus 로고    scopus 로고
    • Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors
    • Billin A.N., Eilers A.L., Queva C., Ayer D.E. Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors. J. Biol. Chem. 1999, 274:36344-36350.
    • (1999) J. Biol. Chem. , vol.274 , pp. 36344-36350
    • Billin, A.N.1    Eilers, A.L.2    Queva, C.3    Ayer, D.E.4
  • 10
    • 0025763419 scopus 로고
    • Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
    • Blackwood E.M., Eisenman R.N. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 1991, 251:1211-1217.
    • (1991) Science , vol.251 , pp. 1211-1217
    • Blackwood, E.M.1    Eisenman, R.N.2
  • 12
    • 0035881691 scopus 로고    scopus 로고
    • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
    • Bouchard C., Dittrich O., Kiermaier A., Dohmann K., Menkel A., Eilers M., Luscher B. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev. 2001, 15:2042-2047.
    • (2001) Genes Dev. , vol.15 , pp. 2042-2047
    • Bouchard, C.1    Dittrich, O.2    Kiermaier, A.3    Dohmann, K.4    Menkel, A.5    Eilers, M.6    Luscher, B.7
  • 16
    • 0038322020 scopus 로고    scopus 로고
    • Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function
    • Choy L., Derynck R. Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. J. Biol. Chem. 2003, 278:9609-9619.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9609-9619
    • Choy, L.1    Derynck, R.2
  • 17
    • 67649595826 scopus 로고    scopus 로고
    • Apoptosis and cancer: the genesis of a research field
    • Cotter T.G. Apoptosis and cancer: the genesis of a research field. Nat. Rev. Cancer 2009, 9:501-507.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 501-507
    • Cotter, T.G.1
  • 18
    • 75649136214 scopus 로고    scopus 로고
    • Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
    • Crotty S., Johnston R.J., Schoenberger S.P. Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat. Immunol. 2010, 11:114-120.
    • (2010) Nat. Immunol. , vol.11 , pp. 114-120
    • Crotty, S.1    Johnston, R.J.2    Schoenberger, S.P.3
  • 19
    • 0030906519 scopus 로고    scopus 로고
    • Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation
    • Cultraro C.M., Bino T., Segal S. Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation. Mol. Cell. Biol. 1997, 17:2353-2359.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2353-2359
    • Cultraro, C.M.1    Bino, T.2    Segal, S.3
  • 21
    • 76249110471 scopus 로고    scopus 로고
    • Rethinking the Warburg effect with Myc micromanaging glutamine metabolism
    • Dang C.V. Rethinking the Warburg effect with Myc micromanaging glutamine metabolism. Cancer Res. 2010, 70:859-862.
    • (2010) Cancer Res. , vol.70 , pp. 859-862
    • Dang, C.V.1
  • 22
    • 40649097065 scopus 로고    scopus 로고
    • IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
    • Descargues P., Sil A.K., Sano Y., Korchynskyi O., Han G., Owens P., Wang X.J., Karin M. IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:2487-2492.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 2487-2492
    • Descargues, P.1    Sil, A.K.2    Sano, Y.3    Korchynskyi, O.4    Han, G.5    Owens, P.6    Wang, X.J.7    Karin, M.8
  • 23
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A., Pandolfi P.P. The multiple roles of PTEN in tumor suppression. Cell 2000, 100:387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 24
  • 25
    • 0032472914 scopus 로고    scopus 로고
    • Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation
    • Foley K.P., McArthur G.A., Queva C., Hurlin P.J., Soriano P., Eisenman R.N. Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. EMBO J. 1998, 17:774-785.
    • (1998) EMBO J. , vol.17 , pp. 774-785
    • Foley, K.P.1    McArthur, G.A.2    Queva, C.3    Hurlin, P.J.4    Soriano, P.5    Eisenman, R.N.6
  • 26
    • 0035886882 scopus 로고    scopus 로고
    • S-phase-specific expression of the Mad3 gene in proliferating and differentiating cells
    • Fox E.J., Wright S.C. S-phase-specific expression of the Mad3 gene in proliferating and differentiating cells. Biochem. J. 2001, 359:361-367.
    • (2001) Biochem. J. , vol.359 , pp. 361-367
    • Fox, E.J.1    Wright, S.C.2
  • 27
    • 76149093576 scopus 로고    scopus 로고
    • Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase
    • Ge Z., Li W., Wang N., Liu C., Zhu Q., Bjorkholm M., Gruber A., Xu D. Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase. FASEB J. 2010, 24:579-586.
    • (2010) FASEB J. , vol.24 , pp. 579-586
    • Ge, Z.1    Li, W.2    Wang, N.3    Liu, C.4    Zhu, Q.5    Bjorkholm, M.6    Gruber, A.7    Xu, D.8
  • 28
    • 0034615931 scopus 로고    scopus 로고
    • Inhibition of proliferation and apoptosis by the transcriptional repressor Mad1. Repression of Fas-induced caspase-8 activation
    • Gehring S., Rottmann S., Menkel A.R., Mertsching J., Krippner-Heidenreich A., Luscher B. Inhibition of proliferation and apoptosis by the transcriptional repressor Mad1. Repression of Fas-induced caspase-8 activation. J. Biol. Chem. 2000, 275:10413-10420.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10413-10420
    • Gehring, S.1    Rottmann, S.2    Menkel, A.R.3    Mertsching, J.4    Krippner-Heidenreich, A.5    Luscher, B.6
  • 30
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 31
    • 0031007189 scopus 로고    scopus 로고
    • Histone deacetylase activity is required for full transcriptional repression by mSin3A
    • Hassig C.A., Fleischer T.C., Billin A.N., Schreiber S.L., Ayer D.E. Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell 1997, 89:341-347.
    • (1997) Cell , vol.89 , pp. 341-347
    • Hassig, C.A.1    Fleischer, T.C.2    Billin, A.N.3    Schreiber, S.L.4    Ayer, D.E.5
  • 32
    • 79951857017 scopus 로고    scopus 로고
    • TGFbeta1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors
    • Hein N., Jiang K., Cornelissen C., Luscher B. TGFbeta1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors. BMC Mol. Biol. 2011, 12:9.
    • (2011) BMC Mol. Biol. , vol.12 , pp. 9
    • Hein, N.1    Jiang, K.2    Cornelissen, C.3    Luscher, B.4
  • 33
    • 0029686266 scopus 로고    scopus 로고
    • Proteins of the Myc network: essential regulators of cell growth and differentiation
    • Henriksson M., Luscher B. Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv. Cancer Res. 1996, 68:109-182.
    • (1996) Adv. Cancer Res. , vol.68 , pp. 109-182
    • Henriksson, M.1    Luscher, B.2
  • 34
    • 33748136848 scopus 로고    scopus 로고
    • The MAX-interacting transcription factor network
    • Hurlin P.J., Huang J. The MAX-interacting transcription factor network. Semin. Cancer Biol. 2006, 16:265-274.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 265-274
    • Hurlin, P.J.1    Huang, J.2
  • 35
    • 0031027008 scopus 로고    scopus 로고
    • Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites
    • Hurlin P.J., Queva C., Eisenman R.N. Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites. Genes Dev. 1997, 11:44-58.
    • (1997) Genes Dev. , vol.11 , pp. 44-58
    • Hurlin, P.J.1    Queva, C.2    Eisenman, R.N.3
  • 36
    • 0028889811 scopus 로고
    • Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
    • Hurlin P.J., Queva C., Koskinen P.J., Steingrimsson E., Ayer D.E., Copeland N.G., Jenkins N.A., Eisenman R.N. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J. 1995, 14:5646-5659.
    • (1995) EMBO J. , vol.14 , pp. 5646-5659
    • Hurlin, P.J.1    Queva, C.2    Koskinen, P.J.3    Steingrimsson, E.4    Ayer, D.E.5    Copeland, N.G.6    Jenkins, N.A.7    Eisenman, R.N.8
  • 37
    • 0343114455 scopus 로고    scopus 로고
    • Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif
    • Hurlin P.J., Steingrimsson E., Copeland N.G., Jenkins N.A., Eisenman R.N. Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif. EMBO J. 1999, 18:7019-7028.
    • (1999) EMBO J. , vol.18 , pp. 7019-7028
    • Hurlin, P.J.1    Steingrimsson, E.2    Copeland, N.G.3    Jenkins, N.A.4    Eisenman, R.N.5
  • 39
    • 78049299607 scopus 로고    scopus 로고
    • FOXM1 expression mediates growth suppression during terminal differentiation of HO-1 human metastatic melanoma cells
    • Huynh K.M., Soh J.W., Dash R., Sarkar D., Fisher P.B., Kang D. FOXM1 expression mediates growth suppression during terminal differentiation of HO-1 human metastatic melanoma cells. J. Cell Physiol. 2011, 226:194-204.
    • (2011) J. Cell Physiol. , vol.226 , pp. 194-204
    • Huynh, K.M.1    Soh, J.W.2    Dash, R.3    Sarkar, D.4    Fisher, P.B.5    Kang, D.6
  • 40
    • 0035884398 scopus 로고    scopus 로고
    • Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas
    • Imoto I., Yang Z.Q., Pimkhaokham A., Tsuda H., Shimada Y., Imamura M., Ohki M., Inazawa J. Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. Cancer Res. 2001, 61:6629-6634.
    • (2001) Cancer Res. , vol.61 , pp. 6629-6634
    • Imoto, I.1    Yang, Z.Q.2    Pimkhaokham, A.3    Tsuda, H.4    Shimada, Y.5    Imamura, M.6    Ohki, M.7    Inazawa, J.8
  • 41
    • 0037119951 scopus 로고    scopus 로고
    • Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1
    • Iritani B.M., Delrow J., Grandori C., Gomez I., Klacking M., Carlos L.S., Eisenman R.N. Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1. EMBO J. 2002, 21:4820-4830.
    • (2002) EMBO J. , vol.21 , pp. 4820-4830
    • Iritani, B.M.1    Delrow, J.2    Grandori, C.3    Gomez, I.4    Klacking, M.5    Carlos, L.S.6    Eisenman, R.N.7
  • 42
    • 0036677401 scopus 로고    scopus 로고
    • Myc and Mad bHLHZ domains possess identical DNA-binding specificities but only partially overlapping functions in vivo
    • James L., Eisenman R.N. Myc and Mad bHLHZ domains possess identical DNA-binding specificities but only partially overlapping functions in vivo. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:10429-10434.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 10429-10434
    • James, L.1    Eisenman, R.N.2
  • 44
    • 0037203546 scopus 로고    scopus 로고
    • Akt: versatile mediator of cell survival and beyond
    • Kim D., Chung J. Akt: versatile mediator of cell survival and beyond. J. Biochem. Mol. Biol. 2002, 35:106-115.
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 106-115
    • Kim, D.1    Chung, J.2
  • 45
    • 77951681449 scopus 로고    scopus 로고
    • Advances in the understanding of MYC-induced lymphomagenesis
    • Klapproth K., Wirth T. Advances in the understanding of MYC-induced lymphomagenesis. Br. J. Haematol. 2010, 149:484-497.
    • (2010) Br. J. Haematol. , vol.149 , pp. 484-497
    • Klapproth, K.1    Wirth, T.2
  • 46
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007, 128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 47
    • 0024205841 scopus 로고
    • The role of the leucine zipper in the fos-jun interaction
    • Kouzarides T., Ziff E. The role of the leucine zipper in the fos-jun interaction. Nature 1988, 336:646-651.
    • (1988) Nature , vol.336 , pp. 646-651
    • Kouzarides, T.1    Ziff, E.2
  • 48
    • 0026737875 scopus 로고
    • Myc and Max proteins possess distinct transcriptional activities
    • Kretzner L., Blackwood E.M., Eisenman R.N. Myc and Max proteins possess distinct transcriptional activities. Nature. 1992, 359:426-429.
    • (1992) Nature. , vol.359 , pp. 426-429
    • Kretzner, L.1    Blackwood, E.M.2    Eisenman, R.N.3
  • 49
    • 0030969516 scopus 로고    scopus 로고
    • Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
    • Laherty C.D., Yang W.M., Sun J.M., Davie J.R., Seto E., Eisenman R.N. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 1997, 89:349-356.
    • (1997) Cell , vol.89 , pp. 349-356
    • Laherty, C.D.1    Yang, W.M.2    Sun, J.M.3    Davie, J.R.4    Seto, E.5    Eisenman, R.N.6
  • 50
    • 0024295767 scopus 로고
    • The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins
    • Landschulz W.H., Johnson P.F., McKnight S.L. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 1988, 240:1759-1764.
    • (1988) Science , vol.240 , pp. 1759-1764
    • Landschulz, W.H.1    Johnson, P.F.2    McKnight, S.L.3
  • 52
    • 0030864848 scopus 로고    scopus 로고
    • Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced differentiation of U-937 monoblasts and F9 teratocarcinoma cells
    • Larsson L.G., Bahram F., Burkhardt H., Luscher B. Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced differentiation of U-937 monoblasts and F9 teratocarcinoma cells. Oncogene 1997, 15:737-748.
    • (1997) Oncogene , vol.15 , pp. 737-748
    • Larsson, L.G.1    Bahram, F.2    Burkhardt, H.3    Luscher, B.4
  • 53
    • 0028299321 scopus 로고
    • Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc
    • Larsson L.G., Pettersson M., Oberg F., Nilsson K., Luscher B. Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc. Oncogene 1994, 9:1247-1252.
    • (1994) Oncogene , vol.9 , pp. 1247-1252
    • Larsson, L.G.1    Pettersson, M.2    Oberg, F.3    Nilsson, K.4    Luscher, B.5
  • 54
    • 0024448304 scopus 로고
    • MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer
    • Lassar A.B., Buskin J.N., Lockshon D., Davis R.L., Apone S., Hauschka S.D., Weintraub H. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell 1989, 58:823-831.
    • (1989) Cell , vol.58 , pp. 823-831
    • Lassar, A.B.1    Buskin, J.N.2    Lockshon, D.3    Davis, R.L.4    Apone, S.5    Hauschka, S.D.6    Weintraub, H.7
  • 56
    • 33645053774 scopus 로고    scopus 로고
    • Mad1 is a transcriptional repressor of Bcl-6
    • Lee S.C., Bottaro A., Chen L., Insel R.A. Mad1 is a transcriptional repressor of Bcl-6. Mol. Immunol. 2006, 43:1965-1971.
    • (2006) Mol. Immunol. , vol.43 , pp. 1965-1971
    • Lee, S.C.1    Bottaro, A.2    Chen, L.3    Insel, R.A.4
  • 57
    • 48549094467 scopus 로고    scopus 로고
    • C-Myc and eIF4F are components of a feedforward loop that links transcription and translation
    • Lin C.J., Cencic R., Mills J.R., Robert F., Pelletier J. c-Myc and eIF4F are components of a feedforward loop that links transcription and translation. Cancer Res. 2008, 68:5326-5334.
    • (2008) Cancer Res. , vol.68 , pp. 5326-5334
    • Lin, C.J.1    Cencic, R.2    Mills, J.R.3    Robert, F.4    Pelletier, J.5
  • 58
    • 0030950523 scopus 로고    scopus 로고
    • Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation
    • Lin Y., Wong K., Calame K. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science 1997, 276:596-599.
    • (1997) Science , vol.276 , pp. 596-599
    • Lin, Y.1    Wong, K.2    Calame, K.3
  • 60
    • 0035904463 scopus 로고    scopus 로고
    • Function and regulation of the transcription factors of the Myc/Max/Mad network
    • Luscher B. Function and regulation of the transcription factors of the Myc/Max/Mad network. Gene 2001, 277:1-14.
    • (2001) Gene , vol.277 , pp. 1-14
    • Luscher, B.1
  • 61
    • 0025607921 scopus 로고
    • New light on Myc and Myb Part I. Myc
    • Luscher B., Eisenman R.N. New light on Myc and Myb Part I. Myc. Genes Dev. 1990, 4:2025-2035.
    • (1990) Genes Dev. , vol.4 , pp. 2025-2035
    • Luscher, B.1    Eisenman, R.N.2
  • 62
    • 0033551393 scopus 로고    scopus 로고
    • The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: function and regulation
    • Luscher B., Larsson L.G. The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: function and regulation. Oncogene 1999, 18:2955-2966.
    • (1999) Oncogene , vol.18 , pp. 2955-2966
    • Luscher, B.1    Larsson, L.G.2
  • 63
    • 33644882481 scopus 로고    scopus 로고
    • Regulation of the transcription factor FOXM1c by Cyclin E/CDK2
    • Luscher-Firzlaff J.M., Lilischkis R., Luscher B. Regulation of the transcription factor FOXM1c by Cyclin E/CDK2. FEBS Lett. 2006, 580:1716-1722.
    • (2006) FEBS Lett. , vol.580 , pp. 1716-1722
    • Luscher-Firzlaff, J.M.1    Lilischkis, R.2    Luscher, B.3
  • 64
    • 0342870489 scopus 로고    scopus 로고
    • Interaction of the fork head domain transcription factor MPP2 with the human papilloma virus 16 E7 protein: enhancement of transformation and transactivation
    • Luscher-Firzlaff J.M., Westendorf J.M., Zwicker J., Burkhardt H., Henriksson M., Muller R., Pirollet F., Luscher B. Interaction of the fork head domain transcription factor MPP2 with the human papilloma virus 16 E7 protein: enhancement of transformation and transactivation. Oncogene 1999, 18:5620-5630.
    • (1999) Oncogene , vol.18 , pp. 5620-5630
    • Luscher-Firzlaff, J.M.1    Westendorf, J.M.2    Zwicker, J.3    Burkhardt, H.4    Henriksson, M.5    Muller, R.6    Pirollet, F.7    Luscher, B.8
  • 66
    • 0034612590 scopus 로고    scopus 로고
    • Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?
    • Meroni G., Cairo S., Merla G., Messali S., Brent R., Ballabio A., Reymond A. Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?. Oncogene 2000, 19:3266-3277.
    • (2000) Oncogene , vol.19 , pp. 3266-3277
    • Meroni, G.1    Cairo, S.2    Merla, G.3    Messali, S.4    Brent, R.5    Ballabio, A.6    Reymond, A.7
  • 67
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas A., Heldin C.H. The regulation of TGFbeta signal transduction. Development 2009, 136:3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 68
    • 0024378079 scopus 로고
    • Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
    • Murre C., McCaw P.S., Vaessin H., Caudy M., Jan L.Y., Jan Y.N., Cabrera C.V., Buskin J.N., Hauschka S.D., Lassar A.B., et al. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 1989, 58:537-544.
    • (1989) Cell , vol.58 , pp. 537-544
    • Murre, C.1    McCaw, P.S.2    Vaessin, H.3    Caudy, M.4    Jan, L.Y.5    Jan, Y.N.6    Cabrera, C.V.7    Buskin, J.N.8    Hauschka, S.D.9    Lassar, A.B.10
  • 71
    • 3242878193 scopus 로고    scopus 로고
    • ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes
    • Ovcharenko I., Nobrega M.A., Loots G.G., Stubbs L. ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucleic Acids Res. 2004, 32:W280-W286.
    • (2004) Nucleic Acids Res. , vol.32
    • Ovcharenko, I.1    Nobrega, M.A.2    Loots, G.G.3    Stubbs, L.4
  • 75
    • 0034011222 scopus 로고    scopus 로고
    • Analysis of Myc/Max/Mad network members in adipogenesis: inhibition of the proliferative burst and differentiation by ectopically expressed Mad1
    • Pulverer B., Sommer A., McArthur G.A., Eisenman R.N., Luscher B. Analysis of Myc/Max/Mad network members in adipogenesis: inhibition of the proliferative burst and differentiation by ectopically expressed Mad1. J. Cell Physiol. 2000, 183:399-410.
    • (2000) J. Cell Physiol. , vol.183 , pp. 399-410
    • Pulverer, B.1    Sommer, A.2    McArthur, G.A.3    Eisenman, R.N.4    Luscher, B.5
  • 76
    • 0042934077 scopus 로고    scopus 로고
    • TGF beta1 induces multiple independent signals to regulate human trophoblastic differentiation: mechanistic insights
    • Rama S., Suresh Y., Rao A.J. TGF beta1 induces multiple independent signals to regulate human trophoblastic differentiation: mechanistic insights. Mol. Cell Endocrinol. 2003, 206:123-136.
    • (2003) Mol. Cell Endocrinol. , vol.206 , pp. 123-136
    • Rama, S.1    Suresh, Y.2    Rao, A.J.3
  • 77
    • 33144481710 scopus 로고    scopus 로고
    • The mad side of the Max network: antagonizing the function of Myc and more
    • Rottmann S., Luscher B. The mad side of the Max network: antagonizing the function of Myc and more. Curr. Top. Microbiol. Immunol. 2006, 302:63-122.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.302 , pp. 63-122
    • Rottmann, S.1    Luscher, B.2
  • 79
    • 42049096743 scopus 로고    scopus 로고
    • Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene
    • Rottmann S., Speckgens S., Luscher-Firzlaff J., Luscher B. Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene. FASEB J. 2008, 22:1124-1134.
    • (2008) FASEB J. , vol.22 , pp. 1124-1134
    • Rottmann, S.1    Speckgens, S.2    Luscher-Firzlaff, J.3    Luscher, B.4
  • 80
    • 0024253756 scopus 로고
    • Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain
    • Sassone-Corsi P., Ransone L.J., Lamph W.W., Verma I.M. Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain. Nature 1988, 336:692-695.
    • (1988) Nature , vol.336 , pp. 692-695
    • Sassone-Corsi, P.1    Ransone, L.J.2    Lamph, W.W.3    Verma, I.M.4
  • 81
    • 33947152396 scopus 로고    scopus 로고
    • The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
    • Secombe J., Li L., Carlos L., Eisenman R.N. The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev. 2007, 21:537-551.
    • (2007) Genes Dev. , vol.21 , pp. 537-551
    • Secombe, J.1    Li, L.2    Carlos, L.3    Eisenman, R.N.4
  • 82
    • 79952851120 scopus 로고    scopus 로고
    • Myc, Mondo, and metabolism
    • Sloan E.J., Ayer D.E. Myc, Mondo, and metabolism. Genes Cancer 2010, 1:587-596.
    • (2010) Genes Cancer , vol.1 , pp. 587-596
    • Sloan, E.J.1    Ayer, D.E.2
  • 83
    • 0032549524 scopus 로고    scopus 로고
    • Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators
    • Sommer A., Bousset K., Kremmer E., Austen M., Luscher B. Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators. J. Biol. Chem. 1998, 273:6632-6642.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6632-6642
    • Sommer, A.1    Bousset, K.2    Kremmer, E.3    Austen, M.4    Luscher, B.5
  • 84
    • 0031172243 scopus 로고    scopus 로고
    • Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity
    • Sommer A., Hilfenhaus S., Menkel A., Kremmer E., Seiser C., Loidl P., Luscher B. Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity. Curr. Biol. 1997, 7:357-365.
    • (1997) Curr. Biol. , vol.7 , pp. 357-365
    • Sommer, A.1    Hilfenhaus, S.2    Menkel, A.3    Kremmer, E.4    Seiser, C.5    Loidl, P.6    Luscher, B.7
  • 87
    • 34249828162 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders
    • Touw I.P., van de Geijn G.J. Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders. Front. Biosci. 2007, 12:800-815.
    • (2007) Front. Biosci. , vol.12 , pp. 800-815
    • Touw, I.P.1    van de Geijn, G.J.2
  • 88
    • 77949920493 scopus 로고    scopus 로고
    • MYC as a regulator of ribosome biogenesis and protein synthesis
    • van Riggelen J., Yetil A., Felsher D.W. MYC as a regulator of ribosome biogenesis and protein synthesis. Nat. Rev. Cancer. 2010, 10:301-309.
    • (2010) Nat. Rev. Cancer. , vol.10 , pp. 301-309
    • van Riggelen, J.1    Yetil, A.2    Felsher, D.W.3
  • 89
    • 53849147183 scopus 로고    scopus 로고
    • Post-translational regulation of the tumor suppressor p27(KIP1)
    • Vervoorts J., Luscher B. Post-translational regulation of the tumor suppressor p27(KIP1). Cell Mol. Life Sci. 2008, 65:3255-3264.
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 3255-3264
    • Vervoorts, J.1    Luscher, B.2
  • 90
    • 33845919326 scopus 로고    scopus 로고
    • The ins and outs of MYC regulation by posttranslational mechanisms
    • Vervoorts J., Luscher-Firzlaff J., Luscher B. The ins and outs of MYC regulation by posttranslational mechanisms. J. Biol. Chem. 2006, 281:34725-34729.
    • (2006) J. Biol. Chem. , vol.281 , pp. 34725-34729
    • Vervoorts, J.1    Luscher-Firzlaff, J.2    Luscher, B.3
  • 91
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I., Sawyers C.L. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer 2002, 2:489-501.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 93
    • 77952569347 scopus 로고    scopus 로고
    • Inducible gene expression: diverse regulatory mechanisms
    • Weake V.M., Workman J.L. Inducible gene expression: diverse regulatory mechanisms. Nat. Rev. Genet. 2010, 11:426-437.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 426-437
    • Weake, V.M.1    Workman, J.L.2
  • 94
    • 0035829654 scopus 로고    scopus 로고
    • The Mad1 transcription factor is a novel target of activin and TGF-beta action in keratinocytes: possible role of Mad1 in wound repair and psoriasis
    • Werner S., Beer H.D., Mauch C., Luscher B., Werner S. The Mad1 transcription factor is a novel target of activin and TGF-beta action in keratinocytes: possible role of Mad1 in wound repair and psoriasis. Oncogene 2001, 20:7494-7504.
    • (2001) Oncogene , vol.20 , pp. 7494-7504
    • Werner, S.1    Beer, H.D.2    Mauch, C.3    Luscher, B.4    Werner, S.5
  • 95
    • 70349782342 scopus 로고    scopus 로고
    • TGF-beta enforces senescence in Myc-transformed hematopoietic tumor cells through induction of Mad1 and repression of Myc activity
    • Wu S., Hultquist A., Hydbring P., Cetinkaya C., Oberg F., Larsson L.G. TGF-beta enforces senescence in Myc-transformed hematopoietic tumor cells through induction of Mad1 and repression of Myc activity. Exp. Cell Res. 2009, 315:3099-3111.
    • (2009) Exp. Cell Res. , vol.315 , pp. 3099-3111
    • Wu, S.1    Hultquist, A.2    Hydbring, P.3    Cetinkaya, C.4    Oberg, F.5    Larsson, L.G.6
  • 96
    • 0035957406 scopus 로고    scopus 로고
    • Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells
    • Xu D., Popov N., Hou M., Wang Q., Bjorkholm M., Gruber A., Menkel A.R., Henriksson M. Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:3826-3831.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 3826-3831
    • Xu, D.1    Popov, N.2    Hou, M.3    Wang, Q.4    Bjorkholm, M.5    Gruber, A.6    Menkel, A.R.7    Henriksson, M.8
  • 98
    • 34247579714 scopus 로고    scopus 로고
    • A tumor suppressor and oncogene: the WT1 story
    • Yang L., Han Y., Suarez Saiz F., Minden M.D. A tumor suppressor and oncogene: the WT1 story. Leukemia 2007, 21:868-876.
    • (2007) Leukemia , vol.21 , pp. 868-876
    • Yang, L.1    Han, Y.2    Suarez Saiz, F.3    Minden, M.D.4
  • 100
    • 0027511606 scopus 로고
    • Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites
    • Zervos A.S., Gyuris J., Brent R. Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 1993, 72:223-232.
    • (1993) Cell , vol.72 , pp. 223-232
    • Zervos, A.S.1    Gyuris, J.2    Brent, R.3
  • 101
    • 44349134920 scopus 로고    scopus 로고
    • Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1
    • Zhu J., Blenis J., Yuan J. Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:6584-6589.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 6584-6589
    • Zhu, J.1    Blenis, J.2    Yuan, J.3
  • 102
    • 0034622020 scopus 로고    scopus 로고
    • Proteasome inhibitor induced gene expression profiles reveal overexpression of transcriptional regulators ATF3, GADD153 and MAD1
    • Zimmermann J., Erdmann D., Lalande I., Grossenbacher R., Noorani M., Furst P. Proteasome inhibitor induced gene expression profiles reveal overexpression of transcriptional regulators ATF3, GADD153 and MAD1. Oncogene 2000, 19:2913-2920.
    • (2000) Oncogene , vol.19 , pp. 2913-2920
    • Zimmermann, J.1    Erdmann, D.2    Lalande, I.3    Grossenbacher, R.4    Noorani, M.5    Furst, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.