메뉴 건너뛰기




Volumn 8, Issue MAY, 2014, Pages

The sodium leak channel, NALCN, in health and disease

Author keywords

Excitability; Ion channel; NALCN; UNC 79; UNC 80

Indexed keywords

CALCIUM CHANNEL; G PROTEIN COUPLED RECEPTOR; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; METABOTROPIC RECEPTOR; MUSCARINIC M3 RECEPTOR; NEUROKININ 1 RECEPTOR; NEUROTENSIN RECEPTOR; NEUROTRANSMITTER; POLYGLUTAMINE; POTASSIUM CHANNEL; PROTEIN TYROSINE KINASE; SCAFFOLD PROTEIN; SODIUM CHANNEL NAV1.2; SODIUM LEAK CHANNEL; TETRODOTOXIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG;

EID: 84901257615     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00132     Document Type: Article
Times cited : (116)

References (160)
  • 1
    • 68249107559 scopus 로고    scopus 로고
    • A genome-wide association study of hypertension and blood pressure in African Americans
    • doi: 10.1371/journal.pgen.10 00564
    • Adeyemo, A., Gerry, N., Chen, G., Herbert, A., Doumatey, A., Huang, H., et al. (2009). A genome-wide association study of hypertension and blood pressure in African Americans. PLoS Genet. 5:e1000564. doi: 10.1371/journal.pgen.10 00564
    • (2009) PLoS Genet , vol.5
    • Adeyemo, A.1    Gerry, N.2    Chen, G.3    Herbert, A.4    Doumatey, A.5    Huang, H.6
  • 2
    • 22044436357 scopus 로고    scopus 로고
    • Is Dandy-Walker malformation associated with "distal 13q deletion syndrome?" Findings in a fetus supporting previous observations
    • doi: 10.1002/ajmg.a.30808
    • Alanay, Y., Aktas, D., Utine, E., Talim, B., Onderoglu, L., Caglar, M., et al. (2005). Is Dandy-Walker malformation associated with "distal 13q deletion syndrome?" Findings in a fetus supporting previous observations. Am. J. Med. Genet. A 136, 265-268. doi: 10.1002/ajmg.a.30808
    • (2005) Am. J. Med. Genet. A , vol.136 , pp. 265-268
    • Alanay, Y.1    Aktas, D.2    Utine, E.3    Talim, B.4    Onderoglu, L.5    Caglar, M.6
  • 4
    • 84885316412 scopus 로고    scopus 로고
    • Mutations in NALCN cause an autosomal-recessive syndrome with severe hypotonia, speech impairment, and cognitive delay
    • doi: 10.1016/j.ajhg.2013.08.001
    • Al-Sayed, M. D., Al-Zaidan, H., Albakheet, A., Hakami, H., Kenana, R., Al-Yafee, Y., et al. (2013). Mutations in NALCN cause an autosomal-recessive syndrome with severe hypotonia, speech impairment, and cognitive delay. Am. J. Hum. Genet. 93, 721-726. doi: 10.1016/j.ajhg.2013.08.001
    • (2013) Am. J. Hum. Genet , vol.93 , pp. 721-726
    • Al-Sayed, M.D.1    Al-Zaidan, H.2    Albakheet, A.3    Hakami, H.4    Kenana, R.5    Al-Yafee, Y.6
  • 5
    • 57349192970 scopus 로고    scopus 로고
    • Conduct disorder and ADHD: Evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study
    • doi: 10.1002/ajmg.b.30871
    • Anney, R. J., Lasky-Su, J., O'Dushlaine, C., Kenny, E., Neale, B. M., Mulligan, A., et al. (2008). Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B, 1369-1378. doi: 10.1002/ajmg.b.30871
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.147 B , pp. 1369-1378
    • Anney, R.J.1    Lasky-Su, J.2    O'Dushlaine, C.3    Kenny, E.4    Neale, B.M.5    Mulligan, A.6
  • 6
    • 33645300737 scopus 로고    scopus 로고
    • From molecule to malady
    • doi: 10.1038/nature04707
    • Ashcroft, F. M. (2006). From molecule to malady. Nature 440, 440-447. doi: 10.1038/nature04707
    • (2006) Nature , vol.440 , pp. 440-447
    • Ashcroft, F.M.1
  • 7
    • 58849112975 scopus 로고    scopus 로고
    • Pathways-based analyses of whole- genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission
    • doi: 10.1007/s00439-008-0600-y
    • Askland, K., Read, C., and Moore, J. (2009). Pathways-based analyses of whole- genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission. Hum. Genet. 125, 63-79. doi: 10.1007/s00439-008-0600-y
    • (2009) Hum. Genet , vol.125 , pp. 63-79
    • Askland, K.1    Read, C.2    Moore, J.3
  • 8
    • 84863731594 scopus 로고    scopus 로고
    • A novel locus for restless legs syndrome on chromosome 13q
    • doi: 10.1159/000338779
    • Balaban, H., Bayrakli, F., Kartal, U., Pinarbasi, E., Topaktas, S., and Kars, H. Z. (2012). A novel locus for restless legs syndrome on chromosome 13q. Eur. Neurol. 68, 111-116. doi: 10.1159/000338779
    • (2012) Eur. Neurol , vol.68 , pp. 111-116
    • Balaban, H.1    Bayrakli, F.2    Kartal, U.3    Pinarbasi, E.4    Topaktas, S.5    Kars, H.Z.6
  • 9
    • 33846898823 scopus 로고    scopus 로고
    • 13q Deletion and central nervous system anomalies: Further insights from karyotype-phenotype analyses of 14 patients
    • doi: 10.1136/jmg.2006.043059
    • Ballarati, L., Rossi, E., Bonati, M. T., Gimelli, S., Maraschio, P., Finelli, P., et al. (2007). 13q Deletion and central nervous system anomalies: further insights from karyotype-phenotype analyses of 14 patients. J. Med. Genet. 44, e60. doi: 10.1136/jmg.2006.043059
    • (2007) J. Med. Genet , vol.44
    • Ballarati, L.1    Rossi, E.2    Bonati, M.T.3    Gimelli, S.4    Maraschio, P.5    Finelli, P.6
  • 10
    • 84897113426 scopus 로고    scopus 로고
    • Integrating the roles of long and small non-coding RNA in brain function and disease
    • doi: 10.1038/mp.2013.196
    • Barry, G. (2014). Integrating the roles of long and small non-coding RNA in brain function and disease. Mol. Psychiatry. 19, 410-416. doi: 10.1038/mp.2013.196
    • (2014) Mol. Psychiatry , vol.19 , pp. 410-416
    • Barry, G.1
  • 11
    • 38349128462 scopus 로고    scopus 로고
    • A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
    • doi: 10.1038/sj.mp.4002012
    • Baum, A. E., Akula, N., Cabanero, M., Cardona, I., Corona, W., Klemens, B., et al. (2008). A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol. Psychiatry 13, 197-207. doi: 10.1038/sj.mp.4002012
    • (2008) Mol. Psychiatry , vol.13 , pp. 197-207
    • Baum, A.E.1    Akula, N.2    Cabanero, M.3    Cardona, I.4    Corona, W.5    Klemens, B.6
  • 12
    • 70349855214 scopus 로고    scopus 로고
    • Daily elec- trical silencing in the mammalian circadian clock
    • doi: 10.1126/science.1169657
    • Belle, M. D., Diekman, C. O., Forger, D. B., and Piggins, H. D. (2009). Daily elec- trical silencing in the mammalian circadian clock. Science 326, 281-284. doi: 10.1126/science.1169657
    • (2009) Science , vol.326 , pp. 281-284
    • Belle, M.D.1    Diekman, C.O.2    Forger, D.B.3    Piggins, H.D.4
  • 13
    • 84869091997 scopus 로고    scopus 로고
    • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
    • doi: 10.1038/nature11547
    • Biankin, A. V., Waddell, N., Kassahn, K. S., Gingras, M. C., Muthuswamy, L. B., Johns, A. L., et al. (2012). Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491, 399-405. doi: 10.1038/nature11547
    • (2012) Nature , vol.491 , pp. 399-405
    • Biankin, A.V.1    Waddell, N.2    Kassahn, K.S.3    Gingras, M.C.4    Muthuswamy, L.B.5    Johns, A.L.6
  • 14
    • 79953851820 scopus 로고    scopus 로고
    • A co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channel
    • doi: 10.1186/1756-6606-4-16
    • Bouhours, M., Po, M. D., Gao, S., Hung, W., Li, H., Georgiou, J., et al. (2011). A co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channel. Mol. Brain 4:16. doi: 10.1186/1756-6606-4-16
    • (2011) Mol. Brain , vol.4 , pp. 16
    • Bouhours, M.1    Po, M.D.2    Gao, S.3    Hung, W.4    Li, H.5    Georgiou, J.6
  • 15
    • 0028982746 scopus 로고
    • The 13q- syndrome: The molecular definition of a critical deletion region in band 13q32
    • Brown, S., Russo, J., Chitayat, D., and Warburton, D. (1995). The 13q- syndrome: the molecular definition of a critical deletion region in band 13q32. Am. J. Hum. Genet. 57, 859-866.
    • (1995) Am. J. Hum. Genet , vol.57 , pp. 859-866
    • Brown, S.1    Russo, J.2    Chitayat, D.3    Warburton, D.4
  • 16
    • 84875803476 scopus 로고    scopus 로고
    • Drosophila social clustering is disrupted by anesthetics and in narrow abdomen ion channel mutants
    • doi: 10.1111/gbb.12025
    • Burg, E. D., Langan, S. T., and Nash, H. A. (2013). Drosophila social clustering is disrupted by anesthetics and in narrow abdomen ion channel mutants. Genes Brain Behav. 12, 338-347. doi: 10.1111/gbb.12025
    • (2013) Genes Brain Behav , vol.12 , pp. 338-347
    • Burg, E.D.1    Langan, S.T.2    Nash, H.A.3
  • 17
    • 0142135448 scopus 로고    scopus 로고
    • An epidemiologic survey of dystonia within the entire population of northeast England over the past nine years
    • Butler, A. G., Duffey, P. O., Hawthorne, M. R., and Barnes, M. P. (2004). An epidemiologic survey of dystonia within the entire population of northeast England over the past nine years. Adv. Neurol. 94, 95-99.
    • (2004) Adv. Neurol , vol.94 , pp. 95-99
    • Butler, A.G.1    Duffey, P.O.2    Hawthorne, M.R.3    Barnes, M.P.4
  • 18
    • 38149129457 scopus 로고    scopus 로고
    • A transcriptome database for astrocytes, neurons, and oligoden- drocytes: A new resource for understanding brain development and function
    • doi: 10.1523/JNEUROSCI.4178-07.2008
    • Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., et al. (2008). A transcriptome database for astrocytes, neurons, and oligoden- drocytes: a new resource for understanding brain development and function. J. Neurosci. 28, 264-278. doi: 10.1523/JNEUROSCI.4178-07.2008
    • (2008) J. Neurosci , vol.28 , pp. 264-278
    • Cahoy, J.D.1    Emery, B.2    Kaushal, A.3    Foo, L.C.4    Zamanian, J.L.5    Christopherson, K.S.6
  • 19
    • 58249084640 scopus 로고    scopus 로고
    • Therapeutic approaches to ion channel diseases
    • doi: 10.1016/S0065-2660(08)00804-3
    • Camerino, D. C., Desaphy, J. F., Tricarico, D., Pierno, S., and Liantonio, A. (2008). Therapeutic approaches to ion channel diseases. Adv. Genet. 64, 81-145. doi: 10.1016/S0065-2660(08)00804-3
    • (2008) Adv. Genet , vol.64 , pp. 81-145
    • Camerino, D.C.1    Desaphy, J.F.2    Tricarico, D.3    Pierno, S.4    Liantonio, A.5
  • 20
    • 0028265206 scopus 로고
    • Use of Drosophila mutants to distinguish among volatile general anesthetics
    • doi: 10.1073/pnas.91.6.2135
    • Campbell, D. B., and Nash, H. A. (1994). Use of Drosophila mutants to distinguish among volatile general anesthetics. Proc. Natl. Acad. Sci. U.S.A. 91, 2135-2139. doi: 10.1073/pnas.91.6.2135
    • (1994) Proc. Natl. Acad. Sci. U.S.A , vol.91 , pp. 2135-2139
    • Campbell, D.B.1    Nash, H.A.2
  • 21
    • 0035196543 scopus 로고    scopus 로고
    • Volatile general anesthetics reveal a neu- robiological role for the white and brown genes of Drosophila melanogaster
    • doi: 10.1002/neu.10009
    • Campbell, J. L., and Nash, H. A. (2001). Volatile general anesthetics reveal a neu- robiological role for the white and brown genes of Drosophila melanogaster. J. Neurobiol. 49, 339-349. doi: 10.1002/neu.10009
    • (2001) J. Neurobiol , vol.49 , pp. 339-349
    • Campbell, J.L.1    Nash, H.A.2
  • 22
    • 78650907529 scopus 로고    scopus 로고
    • Mining recent brain proteomic databases for ion channel phosphosite nuggets
    • doi: 10.1085/jgp.201010555
    • Cerda, O., Baek, J. H., and Trimmer, J. S. (2011). Mining recent brain proteomic databases for ion channel phosphosite nuggets. J. Gen. Physiol. 137, 3-16. doi: 10.1085/jgp.201010555
    • (2011) J. Gen. Physiol , vol.137 , pp. 3-16
    • Cerda, O.1    Baek, J.H.2    Trimmer, J.S.3
  • 23
    • 77956042806 scopus 로고    scopus 로고
    • New insights into the molecular mechanisms of general anaes- thetics
    • doi: 10.1111/j.1476-5381.2010.00891.x
    • Chau, P. L. (2010). New insights into the molecular mechanisms of general anaes- thetics. Br. J. Pharmacol. 161, 288-307. doi: 10.1111/j.1476-5381.2010.00891.x
    • (2010) Br. J. Pharmacol , vol.161 , pp. 288-307
    • Chau, P.L.1
  • 24
    • 77953697090 scopus 로고    scopus 로고
    • Targeting ion channels for drug discovery
    • Clare, J. J. (2010). Targeting ion channels for drug discovery. Discov. Med. 9, 253-260.
    • (2010) Discov. Med , vol.9 , pp. 253-260
    • Clare, J.J.1
  • 25
    • 0006999635 scopus 로고
    • Infantile neuroaxonal dystrophy
    • doi: 10.1097/00005072-196304000- 00001
    • Cowen, D., and Olmstead, E. V. (1963). Infantile neuroaxonal dystrophy. J. Neuropathol. Exp. Neurol. 22, 175-236. doi: 10.1097/00005072-196304000- 00001
    • (1963) J. Neuropathol. Exp. Neurol , vol.22 , pp. 175-236
    • Cowen, D.1    Olmstead, E.V.2
  • 26
    • 0032736675 scopus 로고    scopus 로고
    • Essential role of phosphoinositide metabolism in synaptic vesicle recycling
    • doi: 10.1016/S0092-8674(00)81649-9
    • Cremona, O., Di Paolo, G., Wenk, M. R., Luthi, A., Kim, W. T., Takei, K., et al. (1999). Essential role of phosphoinositide metabolism in synaptic vesicle recycling. Cell 99, 179-188. doi: 10.1016/S0092-8674(00)81649-9
    • (1999) Cell , vol.99 , pp. 179-188
    • Cremona, O.1    Di Paolo, G.2    Wenk, M.R.3    Luthi, A.4    Kim, W.T.5    Takei, K.6
  • 27
    • 67649973701 scopus 로고    scopus 로고
    • Supramolecular assemblies and local- ized regulation of voltage-gated ion channels
    • doi: 10.1152/physrev.00029.2007
    • Dai, S., Hall, D. D., and Hell, J. W. (2009). Supramolecular assemblies and local- ized regulation of voltage-gated ion channels. Physiol. Rev. 89, 411-452. doi: 10.1152/physrev.00029.2007
    • (2009) Physiol. Rev , vol.89 , pp. 411-452
    • Dai, S.1    Hall, D.D.2    Hell, J.W.3
  • 28
    • 84885182447 scopus 로고    scopus 로고
    • Restless legs syndrome: Update on pathogenesis
    • doi: 10.1097/MCP.0b013e328365ab07
    • Dauvilliers, Y., and Winkelmann, J. (2013). Restless legs syndrome: update on pathogenesis. Curr. Opin. Pulm. Med. 19, 594-600. doi: 10.1097/MCP.0b013e328365ab07
    • (2013) Curr. Opin. Pulm. Med , vol.19 , pp. 594-600
    • Dauvilliers, Y.1    Winkelmann, J.2
  • 29
    • 33745689721 scopus 로고    scopus 로고
    • G72/G30 in schizophrenia and bipolar disorder: Review and meta-analysis
    • doi: 10.1016/j.biopsych.2006.01.019
    • Detera-Wadleigh, S. D., and McMahon, F. J. (2006). G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis. Biol. Psychiatry 60, 106-114. doi: 10.1016/j.biopsych.2006.01.019
    • (2006) Biol. Psychiatry , vol.60 , pp. 106-114
    • Detera-Wadleigh, S.D.1    McMahon, F.J.2
  • 30
    • 84856357672 scopus 로고    scopus 로고
    • Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies
    • EPICURE Consortium, doi: 10.1111/j.1528-1167.2011.03379.x
    • EPICURE Consortium, Leu, C., De Kovel, C. G., Zara, F., Striano, P., Pezzella, M., et al. (2012). Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies. Epilepsia 53, 308-318. doi: 10.1111/j.1528-1167.2011.03379.x
    • (2012) Epilepsia , vol.53 , pp. 308-318
    • Leu, C.1    de Kovel, C.G.2    Zara, F.3    Striano, P.4    Pezzella, M.5
  • 31
    • 0033745810 scopus 로고    scopus 로고
    • A preva- lence study of primary dystonia in eight European countries
    • Epidemiological Study of Dystonia in Europe Collaborative, G, doi: 10.1007/s004150070094
    • Epidemiological Study of Dystonia in Europe Collaborative, G. (2000). A preva- lence study of primary dystonia in eight European countries. J. Neurol. 247, 787-792. doi: 10.1007/s004150070094
    • (2000) J. Neurol , vol.247 , pp. 787-792
  • 33
    • 84873621305 scopus 로고    scopus 로고
    • Understanding the rhythm of breathing: So near, yet so far
    • doi: 10.1146/annurev-physiol-040510-130049
    • Feldman, J. L., Del Negro, C. A., and Gray, P. A. (2013). Understanding the rhythm of breathing: so near, yet so far. Annu. Rev. Physiol. 75, 423-452. doi: 10.1146/annurev-physiol-040510-130049
    • (2013) Annu. Rev. Physiol , vol.75 , pp. 423-452
    • Feldman, J.L.1    Del Negro, C.A.2    Gray, P.A.3
  • 34
    • 84872042841 scopus 로고    scopus 로고
    • Combined analysis of genome-wide expression and copy number profiles to identify key altered genomic regions in cancer
    • doi: 10.1186/1471-2164-13-S5-S5
    • Fontanillo, C., Aibar, S., Sanchez-Santos, J. M., and De Las Rivas, J. (2012). Combined analysis of genome-wide expression and copy number profiles to identify key altered genomic regions in cancer. BMC Genomics 13(Suppl. 5):S5. doi: 10.1186/1471-2164-13-S5-S5
    • (2012) BMC Genomics , vol.13 , Issue.SUPPL. 5
    • Fontanillo, C.1    Aibar, S.2    Sanchez-Santos, J.M.3    De Las Rivas, J.4
  • 35
    • 33746358497 scopus 로고    scopus 로고
    • Deletion mapping of critical region for hypospadias, penoscro- tal transposition and imperforate anus on human chromosome 13
    • doi: 10.1016/j.jpurol.2006.03.006
    • Garcia, N. M., Allgood, J., Santos, L. J., Lonergan, D., Batanian, J. R., Henkemeyer, M., et al. (2006). Deletion mapping of critical region for hypospadias, penoscro- tal transposition and imperforate anus on human chromosome 13. J. Pediatr. Urol. 2, 233-242. doi: 10.1016/j.jpurol.2006.03.006
    • (2006) J. Pediatr. Urol , vol.2 , pp. 233-242
    • Garcia, N.M.1    Allgood, J.2    Santos, L.J.3    Lonergan, D.4    Batanian, J.R.5    Henkemeyer, M.6
  • 36
    • 84886252113 scopus 로고    scopus 로고
    • RNA in unexpected places: Long non-coding RNA functions in diverse cellular contexts
    • doi: 10.1038/nrm3679
    • Geisler, S., and Coller, J. (2013). RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts. Nat. Rev. Mol. Cell Biol. 14, 699-712. doi: 10.1038/nrm3679
    • (2013) Nat. Rev. Mol. Cell Biol , vol.14 , pp. 699-712
    • Geisler, S.1    Coller, J.2
  • 37
    • 84897421662 scopus 로고    scopus 로고
    • Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals
    • doi: 10.3389/fnmol.2014.00015
    • Ghezzi A., Liebeskind, B. J., Thompson A., Atkinson, N. S., and Zakonm H. H. (2014). Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals. Front. Mol. Neurosci. 7:15. doi: 10.3389/fnmol.2014.00015
    • (2014) Front. Mol. Neurosci , vol.7 , pp. 15
    • Ghezzi, A.1    Liebeskind, B.J.2    Thompson, A.3    Atkinson, N.S.4    Zakonm, H.H.5
  • 38
    • 69949162421 scopus 로고    scopus 로고
    • NALCN: A regulated leak channel
    • doi: 10.1038/embor.2009.185
    • Gilon, P., and Rorsman, P. (2009). NALCN: a regulated leak channel. EMBO Rep. 10, 963-964. doi: 10.1038/embor.2009.185
    • (2009) EMBO Rep , vol.10 , pp. 963-964
    • Gilon, P.1    Rorsman, P.2
  • 39
    • 79959509957 scopus 로고
    • PLA2G6-associated neurodegeneration
    • eds R. A. Pagon, M. P. Adam, T. D. Bird, C. R. Dolan, C. T. Fong, and K. Stephens (Seattle, WA). Available onlin
    • Gregory, A., Kurian, M. A., Maher, E. R., Hogarth, P., and Hayflick, S. J. (1993). "PLA2G6-associated neurodegeneration," in GeneReviews, eds R. A. Pagon, M. P. Adam, T. D. Bird, C. R. Dolan, C. T. Fong, and K. Stephens (Seattle, WA). Available online at: http://www.ncbi.nlm.nih.gov/books/NBK1675/
    • (1993) In GeneReviews
    • Gregory, A.1    Kurian, M.A.2    Maher, E.R.3    Hogarth, P.4    Hayflick, S.J.5
  • 40
    • 84874226469 scopus 로고    scopus 로고
    • Cervical dystonia and genetic common varia- tion in the dopamine pathway
    • doi: 10.1016/j.parkreldis.2012.08.016
    • Groen, J. L., Simon-Sanchez, J., Ritz, K., Bochdanovits, Z., Fang, Y., Van Hilten, J. J., et al. (2013). Cervical dystonia and genetic common varia- tion in the dopamine pathway. Parkinsonism Relat. Disord. 19, 346-349. doi: 10.1016/j.parkreldis.2012.08.016
    • (2013) Parkinsonism Relat. Disord , vol.19 , pp. 346-349
    • Groen, J.L.1    Simon-Sanchez, J.2    Ritz, K.3    Bochdanovits, Z.4    Fang, Y.5    van Hilten, J.J.6
  • 41
    • 34447559923 scopus 로고    scopus 로고
    • Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants
    • doi: 10.1093/hmg/ddm031
    • Grupe, A., Abraham, R., Li, Y., Rowland, C., Hollingworth, P., Morgan, A., et al. (2007). Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum. Mol. Genet. 16, 865-873. doi: 10.1093/hmg/ddm031
    • (2007) Hum. Mol. Genet , vol.16 , pp. 865-873
    • Grupe, A.1    Abraham, R.2    Li, Y.3    Rowland, C.4    Hollingworth, P.5    Morgan, A.6
  • 42
    • 1642457188 scopus 로고    scopus 로고
    • Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane
    • doi: 10.1124/mol.65.2.443
    • Gruss, M., Bushell, T. J., Bright, D. P., Lieb, W. R., Mathie, A., and Franks, N. P. (2004). Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane. Mol. Pharmacol. 65, 443-452. doi: 10.1124/mol.65.2.443
    • (2004) Mol. Pharmacol , vol.65 , pp. 443-452
    • Gruss, M.1    Bushell, T.J.2    Bright, D.P.3    Lieb, W.R.4    Mathie, A.5    Franks, N.P.6
  • 43
    • 0034014787 scopus 로고    scopus 로고
    • A new assay for the genetic study of general anesthesia in Drosophila melanogaster: Use in analysis of mutations in the X-chromosomal 12E region
    • doi: 10.3109/01677060009083475
    • Guan, Z., Scott, R. L., and Nash, H. A. (2000). A new assay for the genetic study of general anesthesia in Drosophila melanogaster: use in analysis of mutations in the X-chromosomal 12E region. J. Neurogenet. 14, 25-42. doi: 10.3109/01677060009083475
    • (2000) J. Neurogenet , vol.14 , pp. 25-42
    • Guan, Z.1    Scott, R.L.2    Nash, H.A.3
  • 44
    • 0029061652 scopus 로고
    • Activation of a nonselective cationic conductance by metabotropic glutamatergic and mus- carinic agonists in CA3 pyramidal neurons of the rat hippocampus
    • Guerineau, N. C., Bossu, J. L., Gahwiler, B. H., and Gerber, U. (1995). Activation of a nonselective cationic conductance by metabotropic glutamatergic and mus- carinic agonists in CA3 pyramidal neurons of the rat hippocampus. J. Neurosci. 15, 4395-4407.
    • (1995) J. Neurosci , vol.15 , pp. 4395-4407
    • Guerineau, N.C.1    Bossu, J.L.2    Gahwiler, B.H.3    Gerber, U.4
  • 46
    • 84875890982 scopus 로고    scopus 로고
    • The immunobiology and patho- physiology of primary biliary cirrhosis
    • doi: 10.1146/annurev-pathol-020712-164014
    • Hirschfield, G. M., and Gershwin, M. E. (2013). The immunobiology and patho- physiology of primary biliary cirrhosis. Annu. Rev. Pathol. 8, 303-330. doi: 10.1146/annurev-pathol-020712-164014
    • (2013) Annu. Rev. Pathol , vol.8 , pp. 303-330
    • Hirschfield, G.M.1    Gershwin, M.E.2
  • 47
    • 67149095289 scopus 로고    scopus 로고
    • Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants
    • doi: 10.1056/NEJMoa0810440
    • Hirschfield, G. M., Liu, X., Xu, C., Lu, Y., Xie, G., Lu, Y., et al. (2009). Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N. Engl. J. Med. 360, 2544-2555. doi: 10.1056/NEJMoa0810440
    • (2009) N. Engl. J. Med , vol.360 , pp. 2544-2555
    • Hirschfield, G.M.1    Liu, X.2    Xu, C.3    Lu, Y.4    Xie, G.5    Lu, Y.6
  • 48
    • 84862811714 scopus 로고    scopus 로고
    • Congenital heart defect and mental retardation in a patient with a 13q33.1-34 deletion
    • doi: 10.1016/j.gene.2012.01.083
    • Huang, C., Yang, Y. F., Yin, N., Chen, J. L., Wang, J., Zhang, H., et al. (2012). Congenital heart defect and mental retardation in a patient with a 13q33.1-34 deletion. Gene 498, 308-310. doi: 10.1016/j.gene.2012.01.083
    • (2012) Gene , vol.498 , pp. 308-310
    • Huang, C.1    Yang, Y.F.2    Yin, N.3    Chen, J.L.4    Wang, J.5    Zhang, H.6
  • 49
    • 33947658882 scopus 로고    scopus 로고
    • A putative cation channel and its novel regula- tor: Cross-species conservation of effects on general anesthesia
    • doi: 10.1016/j.cub.2007.02.037
    • Humphrey, J. A., Hamming, K. S., Thacker, C. M., Scott, R. L., Sedensky, M. M., Snutch, T. P., et al. (2007). A putative cation channel and its novel regula- tor: cross-species conservation of effects on general anesthesia. Curr. Biol. 17, 624-629. doi: 10.1016/j.cub.2007.02.037
    • (2007) Curr. Biol , vol.17 , pp. 624-629
    • Humphrey, J.A.1    Hamming, K.S.2    Thacker, C.M.3    Scott, R.L.4    Sedensky, M.M.5    Snutch, T.P.6
  • 50
    • 84860297457 scopus 로고    scopus 로고
    • De novo gene disruptions in children on the autistic spectrum
    • doi: 10.1016/j.neuron.2012.04.009
    • Iossifov, I., Ronemus, M., Levy, D., Wang, Z., Hakker, I., Rosenbaum, J., et al. (2012). De novo gene disruptions in children on the autistic spectrum. Neuron 74, 285-299. doi: 10.1016/j.neuron.2012.04.009
    • (2012) Neuron , vol.74 , pp. 285-299
    • Iossifov, I.1    Ronemus, M.2    Levy, D.3    Wang, Z.4    Hakker, I.5    Rosenbaum, J.6
  • 51
    • 84861653161 scopus 로고    scopus 로고
    • Voltage-gated potassium channels and the diversity of electrical signalling
    • doi: 10.1113/jphys- iol.2011.224212
    • Jan, L. Y., and Jan, Y. N. (2012). Voltage-gated potassium channels and the diversity of electrical signalling. J. Physiol. 590, 2591-2599. doi: 10.1113/jphys- iol.2011.224212
    • (2012) J. Physiol , vol.590 , pp. 2591-2599
    • Jan, L.Y.1    Jan, Y.N.2
  • 52
    • 34648814423 scopus 로고    scopus 로고
    • Prevalence of cervical dystonia and spasmodic torticollis in the United States general population
    • doi: 10.1016/j.parkreldis.2007.02.005
    • Jankovic, J., Tsui, J., and Bergeron, C. (2007). Prevalence of cervical dystonia and spasmodic torticollis in the United States general population. Parkinsonism Relat. Disord. 13, 411-416. doi: 10.1016/j.parkreldis.2007.02.005
    • (2007) Parkinsonism Relat. Disord , vol.13 , pp. 411-416
    • Jankovic, J.1    Tsui, J.2    Bergeron, C.3
  • 53
    • 84894249052 scopus 로고    scopus 로고
    • Developmental pathways to autism: A review of prospective studies of infants at risk
    • doi: 10.1016/j.neubiorev.2013.12.001
    • Jones, E. J., Gliga, T., Bedford, R., Charman, T., and Johnson, M. H. (2014). Developmental pathways to autism: a review of prospective studies of infants at risk. Neurosci. Biobehav. Rev. 39C, 1-33. doi: 10.1016/j.neubiorev.2013.12.001
    • (2014) Neurosci. Biobehav. Rev , vol.39 C , pp. 1-33
    • Jones, E.J.1    Gliga, T.2    Bedford, R.3    Charman, T.4    Johnson, M.H.5
  • 54
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • doi: 10.1126/science.1164368
    • Jones, S., Zhang, X., Parsons, D. W., Lin, J. C., Leary, R. J., Angenendt, P., et al. (2008). Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321, 1801-1806. doi: 10.1126/science.1164368
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3    Lin, J.C.4    Leary, R.J.5    Angenendt, P.6
  • 55
    • 34548499323 scopus 로고    scopus 로고
    • UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants
    • doi: 10.1016/j.cub.2007. 08.036
    • Jospin, M., Watanabe, S., Joshi, D., Young, S., Hamming, K., Thacker, C., et al. (2007). UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants. Curr. Biol. 17, 1595-1600. doi: 10.1016/j.cub.2007. 08.036
    • (2007) Curr. Biol , vol.17 , pp. 1595-1600
    • Jospin, M.1    Watanabe, S.2    Joshi, D.3    Young, S.4    Hamming, K.5    Thacker, C.6
  • 56
    • 42949108787 scopus 로고    scopus 로고
    • Ion channels as drug targets: The next GPCRs
    • doi: 10.1085/jgp.200709946
    • Kaczorowski, G. J., McManus, O. B., Priest, B. T., and Garcia, M. L. (2008). Ion channels as drug targets: the next GPCRs. J. Gen. Physiol. 131, 399-405. doi: 10.1085/jgp.200709946
    • (2008) J. Gen. Physiol , vol.131 , pp. 399-405
    • Kaczorowski, G.J.1    McManus, O.B.2    Priest, B.T.3    Garcia, M.L.4
  • 57
    • 80054993342 scopus 로고    scopus 로고
    • Spatio-temporal transcriptome of the human brain
    • doi: 10.1038/nature10523
    • Kang, H. J., Kawasawa, Y. I., Cheng, F., Zhu, Y., Xu, X., Li, M., et al. (2011). Spatio-temporal transcriptome of the human brain. Nature 478, 483-489. doi: 10.1038/nature10523
    • (2011) Nature , vol.478 , pp. 483-489
    • Kang, H.J.1    Kawasawa, Y.I.2    Cheng, F.3    Zhu, Y.4    Xu, X.5    Li, M.6
  • 58
    • 84893827276 scopus 로고    scopus 로고
    • Epileptic encephalopathies: An overview
    • doi: 10.1155/2012/403592
    • Khan, S., and Al Baradie, R. (2012). Epileptic encephalopathies: an overview. Epilepsy Res. Treat. 2012:403592. doi: 10.1155/2012/403592
    • (2012) Epilepsy Res. Treat. 2012 , pp. 403592
    • Khan, S.1    Al Baradie, R.2
  • 59
    • 33751110649 scopus 로고    scopus 로고
    • PLA2G6 mutation underlies infantile neuroaxonal dystrophy
    • doi: 10.1086/508572
    • Khateeb, S., Flusser, H., Ofir, R., Shelef, I., Narkis, G., Vardi, G., et al. (2006). PLA2G6 mutation underlies infantile neuroaxonal dystrophy. Am. J. Hum. Genet. 79, 942-948. doi: 10.1086/508572
    • (2006) Am. J. Hum. Genet , vol.79 , pp. 942-948
    • Khateeb, S.1    Flusser, H.2    Ofir, R.3    Shelef, I.4    Narkis, G.5    Vardi, G.6
  • 60
    • 84859921193 scopus 로고    scopus 로고
    • Involvement of Na(+)-leak channel in substance P-induced depolarization of pacemaking activity in interstitial cells of Cajal
    • doi: 10.1159/000338504
    • Kim, B. J., Chang, I. Y., Choi, S., Jun, J. Y., Jeon, J. H., Xu, W. X., et al. (2012). Involvement of Na(+)-leak channel in substance P-induced depolarization of pacemaking activity in interstitial cells of Cajal. Cell. Physiol. Biochem. 29, 501-510. doi: 10.1159/000338504
    • (2012) Cell. Physiol. Biochem , vol.29 , pp. 501-510
    • Kim, B.J.1    Chang, I.Y.2    Choi, S.3    Jun, J.Y.4    Jeon, J.H.5    Xu, W.X.6
  • 61
    • 66849135271 scopus 로고    scopus 로고
    • Phenotype and 244k array-CGH characterization of chromosome 13q deletions: An update of the phenotypic map of 13q21.1-qter
    • doi: 10.1002/ajmg.a.32814
    • Kirchhoff, M., Bisgaard, A. M., Stoeva, R., Dimitrov, B., Gillessen-Kaesbach, G., Fryns, J. P., et al. (2009). Phenotype and 244k array-CGH characterization of chromosome 13q deletions: an update of the phenotypic map of 13q21.1-qter. Am. J. Med. Genet. A 149A, 894-905. doi: 10.1002/ajmg.a.32814
    • (2009) Am. J. Med. Genet. A , vol.149 A , pp. 894-905
    • Kirchhoff, M.1    Bisgaard, A.M.2    Stoeva, R.3    Dimitrov, B.4    Gillessen-Kaesbach, G.5    Fryns, J.P.6
  • 62
    • 84883158819 scopus 로고    scopus 로고
    • Recessive truncating NALCN muta- tion in infantile neuroaxonal dystrophy with facial dysmorphism
    • doi: 10.1136/jmedgenet-2013-101634
    • Koroglu, C., Seven, M., and Tolun, A. (2013). Recessive truncating NALCN muta- tion in infantile neuroaxonal dystrophy with facial dysmorphism. J. Med. Genet. 50, 515-520. doi: 10.1136/jmedgenet-2013-101634
    • (2013) J. Med. Genet , vol.50 , pp. 515-520
    • Koroglu, C.1    Seven, M.2    Tolun, A.3
  • 63
    • 0025016343 scopus 로고
    • A genetic study of the anesthetic response: Mutants of Drosophila melanogaster altered in sensitivity to halothane
    • doi: 10.1073/pnas.87.21.8632
    • Krishnan, K. S., and Nash, H. A. (1990). A genetic study of the anesthetic response: mutants of Drosophila melanogaster altered in sensitivity to halothane. Proc. Natl. Acad. Sci. U.S.A. 87, 8632-8636. doi: 10.1073/pnas.87.21.8632
    • (1990) Proc. Natl. Acad. Sci. U.S.A , vol.87 , pp. 8632-8636
    • Krishnan, K.S.1    Nash, H.A.2
  • 65
    • 84872492830 scopus 로고    scopus 로고
    • Rare DNA copy number variants in cardiovascular malforma- tions with extracardiac abnormalities
    • doi: 10.1038/ejhg.2012.155
    • Lalani, S. R., Shaw, C., Wang, X., Patel, A., Patterson, L. W., Kolodziejska, K., et al. (2013). Rare DNA copy number variants in cardiovascular malforma- tions with extracardiac abnormalities. Eur. J. Hum. Genet. 21, 173-181. doi: 10.1038/ejhg.2012.155
    • (2013) Eur. J. Hum. Genet , vol.21 , pp. 173-181
    • Lalani, S.R.1    Shaw, C.2    Wang, X.3    Patel, A.4    Patterson, L.W.5    Kolodziejska, K.6
  • 66
    • 84892374922 scopus 로고    scopus 로고
    • UNC79 and UNC80, putative auxiliary subunits of the NARROW ABDOMEN ion channel, are indispensable for robust circadian locomotor rhythms in Drosophila
    • doi: 10.1371/journal.pone.00 78147
    • Lear, B. C., Darrah, E. J., Aldrich, B. T., Gebre, S., Scott, R. L., Nash, H. A., et al. (2013). UNC79 and UNC80, putative auxiliary subunits of the NARROW ABDOMEN ion channel, are indispensable for robust circadian locomotor rhythms in Drosophila. PLoS ONE 8:e78147. doi: 10.1371/journal.pone.00 78147
    • (2013) PLoS ONE , vol.8
    • Lear, B.C.1    Darrah, E.J.2    Aldrich, B.T.3    Gebre, S.4    Scott, R.L.5    Nash, H.A.6
  • 67
    • 29144447019 scopus 로고    scopus 로고
    • The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker
    • doi: 10.1016/j.neuron.2005.10.030
    • Lear, B. C., Lin, J. M., Keath, J. R., McGill, J. J., Raman, I. M., and Allada, R. (2005). The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker. Neuron 48, 965-976. doi: 10.1016/j.neuron.2005.10.030
    • (2005) Neuron , vol.48 , pp. 965-976
    • Lear, B.C.1    Lin, J.M.2    Keath, J.R.3    McGill, J.J.4    Raman, I.M.5    Allada, R.6
  • 68
    • 38649102180 scopus 로고    scopus 로고
    • Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease
    • doi: 10.1007/s10048-007-0103-3
    • Lee, J. H., Barral, S., Cheng, R., Chacon, I., Santana, V., Williamson, J., et al. (2008). Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease. Neurogenetics 9, 51-60. doi: 10.1007/s10048-007-0103-3
    • (2008) Neurogenetics , vol.9 , pp. 51-60
    • Lee, J.H.1    Barral, S.2    Cheng, R.3    Chacon, I.4    Santana, V.5    Williamson, J.6
  • 69
    • 0033051150 scopus 로고    scopus 로고
    • Cloning of a novel four repeat protein related to voltage-gated sodium and calcium channels
    • doi: 10.1016/S0014-5793(99)00082-4
    • Lee, J. H., Cribbs, L. L., and Perez-Reyes, E. (1999). Cloning of a novel four repeat protein related to voltage-gated sodium and calcium channels. FEBS Lett. 445, 231-236. doi: 10.1016/S0014-5793(99)00082-4
    • (1999) FEBS Lett , vol.445 , pp. 231-236
    • Lee, J.H.1    Cribbs, L.L.2    Perez-Reyes, E.3
  • 70
    • 84873545064 scopus 로고    scopus 로고
    • Prognostic impli- cations of genetic variants in advanced non-small cell lung cancer: A genome- wide association study
    • doi: 10.1093/carcin/bgs356
    • Lee, Y., Yoon, K. A., Joo, J., Lee, D., Bae, K., Han, J. Y., et al. (2013). Prognostic impli- cations of genetic variants in advanced non-small cell lung cancer: a genome- wide association study. Carcinogenesis 34, 307-313. doi: 10.1093/carcin/bgs356
    • (2013) Carcinogenesis , vol.34 , pp. 307-313
    • Lee, Y.1    Yoon, K.A.2    Joo, J.3    Lee, D.4    Bae, K.5    Han, J.Y.6
  • 71
    • 0001481476 scopus 로고
    • Chromosome Deletion in a Case of Retinoblastoma
    • doi: 10.1111/j.1469- 1809.1963.tb00209.x
    • Lele, K. P., Penrose, L. S., and Stallard, H. B. (1963). Chromosome Deletion in a Case of Retinoblastoma. Ann. Hum. Genet. 27, 171-174. doi: 10.1111/j.1469- 1809.1963.tb00209.x
    • (1963) Ann. Hum. Genet , vol.27 , pp. 171-174
    • Lele, K.P.1    Penrose, L.S.2    Stallard, H.B.3
  • 72
    • 0037042065 scopus 로고    scopus 로고
    • Endophenotypes in bipolar disorder
    • doi: 10.1002/ajmg.10360
    • Lenox, R. H., Gould, T. D., and Manji, H. K. (2002). Endophenotypes in bipolar disorder. Am. J. Med. Genet. 114, 391-406. doi: 10.1002/ajmg.10360
    • (2002) Am. J. Med. Genet , vol.114 , pp. 391-406
    • Lenox, R.H.1    Gould, T.D.2    Manji, H.K.3
  • 73
    • 84873708403 scopus 로고    scopus 로고
    • Ion channels in genetic and acquired forms of epilepsy
    • doi: 10.1113/jphysiol.2012.240606
    • Lerche, H., Shah, M., Beck, H., Noebels, J., Johnston, D., and Vincent, A. (2013). Ion channels in genetic and acquired forms of epilepsy. J. Physiol. 591, 753-764. doi: 10.1113/jphysiol.2012.240606
    • (2013) J. Physiol , vol.591 , pp. 753-764
    • Lerche, H.1    Shah, M.2    Beck, H.3    Noebels, J.4    Johnston, D.5    Vincent, A.6
  • 74
    • 84869076149 scopus 로고    scopus 로고
    • Phylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage- insensitive clade
    • doi: 10.1093/molbev/mss182
    • Liebeskind, B. J., Hillis, D. M., and Zakon, H. H. (2012). Phylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage- insensitive clade. Mol. Biol. Evol. 29, 3613-3616. doi: 10.1093/molbev/mss182
    • (2012) Mol. Biol. Evol , vol.29 , pp. 3613-3616
    • Liebeskind, B.J.1    Hillis, D.M.2    Zakon, H.H.3
  • 75
    • 77953247314 scopus 로고    scopus 로고
    • A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations
    • doi: 10.1375/twin.13.1.10
    • Lind, P. A., Macgregor, S., Vink, J. M., Pergadia, M. L., Hansell, N. K., De Moor, M. H., et al. (2010). A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. Twin Res. Hum. Genet. 13, 10-29. doi: 10.1375/twin.13.1.10
    • (2010) Twin Res. Hum. Genet , vol.13 , pp. 10-29
    • Lind, P.A.1    Macgregor, S.2    Vink, J.M.3    Pergadia, M.L.4    Hansell, N.K.5    de Moor, M.H.6
  • 76
    • 84876889067 scopus 로고    scopus 로고
    • Alternative splicing: Functional diversity among voltage-gated calcium channels and behavioral consequences
    • doi: 10.1016/j.bbamem.2012.09.018
    • Lipscombe, D., Andrade, A., and Allen, S. E. (2013). Alternative splicing: functional diversity among voltage-gated calcium channels and behavioral consequences. Biochim. Biophys. Acta 1828, 1522-1529. doi: 10.1016/j.bbamem.2012.09.018
    • (2013) Biochim. Biophys. Acta , vol.1828 , pp. 1522-1529
    • Lipscombe, D.1    Andrade, A.2    Allen, S.E.3
  • 77
    • 9244228006 scopus 로고    scopus 로고
    • Potent acti- vation of the human tandem pore domain K channel TRESK with clinical concentrations of volatile anesthetics
    • doi: 10.1213/01.ANE.0000136849.07384.44
    • Liu, C., Au, J. D., Zou, H. L., Cotten, J. F., and Yost, C. S. (2004). Potent acti- vation of the human tandem pore domain K channel TRESK with clinical concentrations of volatile anesthetics. Anesth. Analg. 99, 1715-1722. doi: 10.1213/01.ANE.0000136849.07384.44
    • (2004) Anesth. Analg , vol.99 , pp. 1715-1722
    • Liu, C.1    Au, J.D.2    Zou, H.L.3    Cotten, J.F.4    Yost, C.S.5
  • 78
    • 34147114722 scopus 로고    scopus 로고
    • The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm
    • doi: 10.1016/j.cell.2007.02.041
    • Lu, B., Su, Y., Das, S., Liu, J., Xia, J., and Ren, D. (2007). The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm. Cell 129, 371-383. doi: 10.1016/j.cell.2007.02.041
    • (2007) Cell , vol.129 , pp. 371-383
    • Lu, B.1    Su, Y.2    Das, S.3    Liu, J.4    Xia, J.5    Ren, D.6
  • 79
    • 59649126876 scopus 로고    scopus 로고
    • Peptide neurotrans- mitters activate a cation channel complex of NALCN and UNC-80
    • doi: 10.1038/nature07579
    • Lu, B., Su, Y., Das, S., Wang, H., Wang, Y., Liu, J., et al. (2009). Peptide neurotrans- mitters activate a cation channel complex of NALCN and UNC-80. Nature 457, 741-744. doi: 10.1038/nature07579
    • (2009) Nature , vol.457 , pp. 741-744
    • Lu, B.1    Su, Y.2    Das, S.3    Wang, H.4    Wang, Y.5    Liu, J.6
  • 80
    • 78049257309 scopus 로고    scopus 로고
    • Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex
    • doi: 10.1016/j.neuron.2010.09.014
    • Lu, B., Zhang, Q., Wang, H., Wang, Y., Nakayama, M., and Ren, D. (2010). Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex. Neuron 68, 488-499. doi: 10.1016/j.neuron.2010.09.014
    • (2010) Neuron , vol.68 , pp. 488-499
    • Lu, B.1    Zhang, Q.2    Wang, H.3    Wang, Y.4    Nakayama, M.5    Ren, D.6
  • 81
    • 79955428552 scopus 로고    scopus 로고
    • A sodium leak current regulates pacemaker activ- ity of adult central pattern generator neurons in Lymnaea stagnalis
    • doi: 10.1371/journal.pone.0018745
    • Lu, T. Z., and Feng, Z. P. (2011). A sodium leak current regulates pacemaker activ- ity of adult central pattern generator neurons in Lymnaea stagnalis. PLoS ONE 6:e18745. doi: 10.1371/journal.pone.0018745
    • (2011) PLoS ONE , vol.6
    • Lu, T.Z.1    Feng, Z.P.2
  • 82
    • 84867481677 scopus 로고    scopus 로고
    • NALCN: A regulator of pacemaker activity
    • doi: 10.1007/s12035-012-8260-2
    • Lu, T. Z., and Feng, Z. P. (2012). NALCN: a regulator of pacemaker activity. Mol. Neurobiol. 45, 415-423. doi: 10.1007/s12035-012-8260-2
    • (2012) Mol. Neurobiol , vol.45 , pp. 415-423
    • Lu, T.Z.1    Feng, Z.P.2
  • 83
    • 0034105691 scopus 로고    scopus 로고
    • Neural tube defects and the 13q deletion syndrome: Evidence for a critical region in 13q33-34
    • doi: 10.1002/(SICI)1096- 8628(20000320)91:3<227::AID-AJMG14>3.0.CO;2-I
    • Luo, J., Balkin, N., Stewart, J. F., Sarwark, J. F., Charrow, J., and Nye, J. S. (2000). Neural tube defects and the 13q deletion syndrome: evidence for a critical region in 13q33-34. Am. J. Med. Genet. 91, 227-230. doi: 10.1002/(SICI)1096- 8628(20000320)91:3<227::AID-AJMG14>3.0.CO;2-I
    • (2000) Am. J. Med. Genet , vol.91 , pp. 227-230
    • Luo, J.1    Balkin, N.2    Stewart, J.F.3    Sarwark, J.F.4    Charrow, J.5    Nye, J.S.6
  • 84
    • 77957887806 scopus 로고    scopus 로고
    • Epileptogenic ion channel mutations: From bedside to bench and, hope- fully, back again
    • doi: 10.1016/j.eplepsyres.2010.08.003
    • Mantegazza, M., Rusconi, R., Scalmani, P., Avanzini, G., and Franceschetti, S. (2010). Epileptogenic ion channel mutations: from bedside to bench and, hope- fully, back again. Epilepsy Res. 92, 1-29. doi: 10.1016/j.eplepsyres.2010.08.003
    • (2010) Epilepsy Res , vol.92 , pp. 1-29
    • Mantegazza, M.1    Rusconi, R.2    Scalmani, P.3    Avanzini, G.4    Franceschetti, S.5
  • 85
    • 0037023682 scopus 로고    scopus 로고
    • Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1
    • doi: 10.1074/jbc.M111603200
    • Maruoka, T., Nagasoe, Y., Inoue, S., Mori, Y., Goto, J., Ikeda, M., et al. (2002). Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1. J. Biol. Chem. 277, 11645-11652. doi: 10.1074/jbc.M111603200
    • (2002) J. Biol. Chem , vol.277 , pp. 11645-11652
    • Maruoka, T.1    Nagasoe, Y.2    Inoue, S.3    Mori, Y.4    Goto, J.5    Ikeda, M.6
  • 86
    • 0036837687 scopus 로고    scopus 로고
    • Partial deletions of the long arm of chromosome 13 associated with holoprosencephaly and the Dandy-Walker malformation
    • doi: 10.1002/ajmg.10659
    • McCormack, W. M. Jr., Shen, J. J., Curry, S. M., Berend, S. A., Kashork, C., Pinar, H., et al. (2002). Partial deletions of the long arm of chromosome 13 associated with holoprosencephaly and the Dandy-Walker malformation. Am. J. Med. Genet. 112, 384-389. doi: 10.1002/ajmg.10659
    • (2002) Am. J. Med. Genet , vol.112 , pp. 384-389
    • McCormack Jr., W.M.1    Shen, J.J.2    Curry, S.M.3    Berend, S.A.4    Kashork, C.5    Pinar, H.6
  • 87
    • 84862110799 scopus 로고    scopus 로고
    • In vivo evolution of tumor-derived endothelial cells
    • doi: 10.1371/journal.pone.0037138
    • McGuire, T. F., Sajithlal, G. B., Lu, J., Nicholls, R. D., and Prochownik, E. V. (2012). In vivo evolution of tumor-derived endothelial cells. PLoS ONE 7:e37138. doi: 10.1371/journal.pone.0037138
    • (2012) PLoS ONE , vol.7
    • McGuire, T.F.1    Sajithlal, G.B.2    Lu, J.3    Nicholls, R.D.4    Prochownik, E.V.5
  • 88
    • 77953101402 scopus 로고    scopus 로고
    • Cytosolic protein interactions of the schizophrenia sus- ceptibility gene dysbindin
    • doi: 10.1111/j.1471- 4159.2010.06690.x
    • Mead, C. L., Kuzyk, M. A., Moradian, A., Wilson, G. M., Holt, R. A., and Morin, G. B. (2010). Cytosolic protein interactions of the schizophrenia sus- ceptibility gene dysbindin. J. Neurochem. 113, 1491-1503. doi: 10.1111/j.1471- 4159.2010.06690.x
    • (2010) J. Neurochem , vol.113 , pp. 1491-1503
    • Mead, C.L.1    Kuzyk, M.A.2    Moradian, A.3    Wilson, G.M.4    Holt, R.A.5    Morin, G.B.6
  • 89
    • 84885028372 scopus 로고    scopus 로고
    • The recent progress in research on effects of anesthetics and analgesics on G protein-coupled receptors
    • doi: 10.1007/s00540-012-1507-2
    • Minami, K., and Uezono, Y. (2013). The recent progress in research on effects of anesthetics and analgesics on G protein-coupled receptors. J. Anesth. 27, 284-292. doi: 10.1007/s00540-012-1507-2
    • (2013) J. Anesth , vol.27 , pp. 284-292
    • Minami, K.1    Uezono, Y.2
  • 90
    • 0030808644 scopus 로고    scopus 로고
    • A genetic and mosaic analysis of a locus involved in the anesthesia response of Drosophila melanogaster
    • Mir, B., Iyer, S., Ramaswami, M., and Krishnan, K. S. (1997). A genetic and mosaic analysis of a locus involved in the anesthesia response of Drosophila melanogaster. Genetics 147, 701-712.
    • (1997) Genetics , vol.147 , pp. 701-712
    • Mir, B.1    Iyer, S.2    Ramaswami, M.3    Krishnan, K.S.4
  • 91
    • 84894278971 scopus 로고    scopus 로고
    • Genomewide association study in cervical dys- tonia demonstrates possible association with sodium leak channel
    • doi: 10.1002/mds.25732
    • Mok, K. Y., Schneider, S. A., Trabzuni, D., Stamelou, M., Edwards, M., Kasperaviciute, D., et al. (2013). Genomewide association study in cervical dys- tonia demonstrates possible association with sodium leak channel. Mov. Disord. 29, 245-251. doi: 10.1002/mds.25732
    • (2013) Mov. Disord , vol.29 , pp. 245-251
    • Mok, K.Y.1    Schneider, S.A.2    Trabzuni, D.3    Stamelou, M.4    Edwards, M.5    Kasperaviciute, D.6
  • 92
    • 33745553895 scopus 로고    scopus 로고
    • PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron
    • doi: 10.1038/ng1826
    • Morgan, N. V., Westaway, S. K., Morton, J. E., Gregory, A., Gissen, P., Sonek, S., et al. (2006). PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron. Nat. Genet. 38, 752-754. doi: 10.1038/ng1826
    • (2006) Nat. Genet , vol.38 , pp. 752-754
    • Morgan, N.V.1    Westaway, S.K.2    Morton, J.E.3    Gregory, A.4    Gissen, P.5    Sonek, S.6
  • 93
    • 0021847545 scopus 로고
    • Effect of anesthetics and a convulsant on normal and mutant Caenorhabditis elegans
    • doi: 10.1097/00000542-198506000-00007
    • Morgan, P. G., and Cascorbi, H. F. (1985). Effect of anesthetics and a convulsant on normal and mutant Caenorhabditis elegans. Anesthesiology 62, 738-744. doi: 10.1097/00000542-198506000-00007
    • (1985) Anesthesiology , vol.62 , pp. 738-744
    • Morgan, P.G.1    Cascorbi, H.F.2
  • 94
    • 0025246776 scopus 로고
    • Multiple sites of action of volatile anesthetics in Caenorhabditis elegans
    • doi: 10.1073/pnas.87.8.2965
    • Morgan, P. G., Sedensky, M., and Meneely, P. M. (1990). Multiple sites of action of volatile anesthetics in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 87, 2965-2969. doi: 10.1073/pnas.87.8.2965
    • (1990) Proc. Natl. Acad. Sci. U.S.A , vol.87 , pp. 2965-2969
    • Morgan, P.G.1    Sedensky, M.2    Meneely, P.M.3
  • 95
    • 0029616380 scopus 로고
    • Mutations affecting sensitivity to ethanol in the nematode, Caenorhabditis elegans
    • doi: 10.1111/j.1530-0277.1995.tb01002.x
    • Morgan, P. G., and Sedensky, M. M. (1995). Mutations affecting sensitivity to ethanol in the nematode, Caenorhabditis elegans. Alcohol. Clin. Exp. Res. 19, 1423-1429. doi: 10.1111/j.1530-0277.1995.tb01002.x
    • (1995) Alcohol. Clin. Exp. Res , vol.19 , pp. 1423-1429
    • Morgan, P.G.1    Sedensky, M.M.2
  • 96
    • 0023807314 scopus 로고
    • The effect of two genes on anesthetic response in the nematode Caenorhabditis elegans
    • doi: 10.1097/00000542-198808000-00015
    • Morgan, P. G., Sedensky, M. M., Meneely, P. M., and Cascorbi, H. F. (1988). The effect of two genes on anesthetic response in the nematode Caenorhabditis elegans. Anesthesiology 69, 246-251. doi: 10.1097/00000542-198808000-00015
    • (1988) Anesthesiology , vol.69 , pp. 246-251
    • Morgan, P.G.1    Sedensky, M.M.2    Meneely, P.M.3    Cascorbi, H.F.4
  • 97
    • 84902377413 scopus 로고    scopus 로고
    • Genetics and genomics of alcohol sensitivity
    • doi: 10.1007/s00438-013-0808-y. [Epub ahead of print]
    • Morozova, T. V., Mackay, T. F., and Anholt, R. R. (2014). Genetics and genomics of alcohol sensitivity. Mol. Genet. Genomics. doi: 10.1007/s00438-013-0808-y. [Epub ahead of print]
    • (2014) Mol. Genet. Genomics
    • Morozova, T.V.1    Mackay, T.F.2    Anholt, R.R.3
  • 98
    • 0037167549 scopus 로고    scopus 로고
    • The prevalence of primary dystonia in the general community
    • doi: 10.1212/01.WNL.0000026474.12594.0D
    • Muller, J., Kiechl, S., Wenning, G. K., Seppi, K., Willeit, J., Gasperi, A., et al. (2002). The prevalence of primary dystonia in the general community. Neurology 59, 941-943. doi: 10.1212/01.WNL.0000026474.12594.0D
    • (2002) Neurology , vol.59 , pp. 941-943
    • Muller, J.1    Kiechl, S.2    Wenning, G.K.3    Seppi, K.4    Willeit, J.5    Gasperi, A.6
  • 99
    • 0029012124 scopus 로고
    • Prevalence of focal dystonias in the western area of Tottori Prefecture in Japan
    • doi: 10.1002/mds.870100406
    • Nakashima, K., Kusumi, M., Inoue, Y., and Takahashi, K. (1995). Prevalence of focal dystonias in the western area of Tottori Prefecture in Japan. Mov. Disord. 10, 440-443. doi: 10.1002/mds.870100406
    • (1995) Mov. Disord , vol.10 , pp. 440-443
    • Nakashima, K.1    Kusumi, M.2    Inoue, Y.3    Takahashi, K.4
  • 100
    • 33845630691 scopus 로고    scopus 로고
    • A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins
    • doi: 10.1096/fj.06-5952fje
    • Nakayama, M., Iida, M., Koseki, H., and Ohara, O. (2006). A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins. FASEB J. 20, 1718-1720. doi: 10.1096/fj.06-5952fje
    • (2006) FASEB J , vol.20 , pp. 1718-1720
    • Nakayama, M.1    Iida, M.2    Koseki, H.3    Ohara, O.4
  • 101
    • 0025737206 scopus 로고
    • New mutants of Drosophila that are resistant to the anesthetic effects of halothane
    • doi: 10.1111/j.1749-6632.1991. tb33885.x
    • Nash, H. A., Campbell, D. B., and Krishnan, K. S. (1991). New mutants of Drosophila that are resistant to the anesthetic effects of halothane. Ann. N.Y. Acad. Sci. 625, 540-544. doi: 10.1111/j.1749-6632.1991. tb33885.x
    • (1991) Ann. N.Y. Acad. Sci , vol.625 , pp. 540-544
    • Nash, H.A.1    Campbell, D.B.2    Krishnan, K.S.3
  • 102
    • 0037164721 scopus 로고    scopus 로고
    • An unusual cation channel mediates photic control of locomotion in Drosophila
    • doi: 10.1016/S0960-9822(02)01358-1
    • Nash, H. A., Scott, R. L., Lear, B. C., and Allada, R. (2002). An unusual cation channel mediates photic control of locomotion in Drosophila. Curr. Biol. 12, 2152-2158. doi: 10.1016/S0960-9822(02)01358-1
    • (2002) Curr. Biol , vol.12 , pp. 2152-2158
    • Nash, H.A.1    Scott, R.L.2    Lear, B.C.3    Allada, R.4
  • 103
    • 0033023215 scopus 로고    scopus 로고
    • Halothane presynaptically depresses synaptic transmission in wild-type Drosophila larvae but not in halothane- resistant (har) mutants
    • doi: 10.1097/00000542- 199906000-00026
    • Nishikawa, K., and Kidokoro, Y. (1999). Halothane presynaptically depresses synaptic transmission in wild-type Drosophila larvae but not in halothane- resistant (har) mutants. Anesthesiology 90, 1691-1697. doi: 10.1097/00000542- 199906000-00026
    • (1999) Anesthesiology , vol.90 , pp. 1691-1697
    • Nishikawa, K.1    Kidokoro, Y.2
  • 104
    • 0037123779 scopus 로고    scopus 로고
    • Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock
    • doi: 10.1016/S0092-8674(02)00737-7
    • Nitabach, M. N., Blau, J., and Holmes, T. C. (2002). Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock. Cell 109, 485-495. doi: 10.1016/S0092-8674(02)00737-7
    • (2002) Cell , vol.109 , pp. 485-495
    • Nitabach, M.N.1    Blau, J.2    Holmes, T.C.3
  • 105
    • 80052626686 scopus 로고    scopus 로고
    • Molecular regulations governing TREK and TRAAK channel functions
    • doi: 10.4161/chan.5.5.16469
    • Noel, J., Sandoz, G., and Lesage, F. (2011). Molecular regulations governing TREK and TRAAK channel functions. Channels (Austin). 5, 402-409. doi: 10.4161/chan.5.5.16469
    • (2011) Channels (Austin) , vol.5 , pp. 402-409
    • Noel, J.1    Sandoz, G.2    Lesage, F.3
  • 106
    • 0035018761 scopus 로고    scopus 로고
    • Evidence for a locus on chromosome 1 that influences vulnerabil- ity to alcoholism and affective disorder
    • doi: 10.1176/appi.ajp.158.5.718
    • Nurnberger, J. I. Jr., Foroud, T., Flury, L., Su, J., Meyer, E. T., Hu, K., et al. (2001). Evidence for a locus on chromosome 1 that influences vulnerabil- ity to alcoholism and affective disorder. Am. J. Psychiatry 158, 718-724. doi: 10.1176/appi.ajp.158.5.718
    • (2001) Am. J. Psychiatry , vol.158 , pp. 718-724
    • Nurnberger Jr., J.I.1    Foroud, T.2    Flury, L.3    Su, J.4    Meyer, E.T.5    Hu, K.6
  • 107
    • 0037417254 scopus 로고    scopus 로고
    • Alzheimer's disease and Parkinson's disease
    • doi: 10.1056/NEJM2003ra020003
    • Nussbaum, R. L., and Ellis, C. E. (2003). Alzheimer's disease and Parkinson's disease. N. Engl. J. Med. 348, 1356-1364. doi: 10.1056/NEJM2003ra020003
    • (2003) N. Engl. J. Med , vol.348 , pp. 1356-1364
    • Nussbaum, R.L.1    Ellis, C.E.2
  • 108
    • 0024228818 scopus 로고
    • Epidemiology of focal and generalized dystonia in Rochester, Minnesota
    • doi: 10.1002/mds.8700 30302
    • Nutt, J. G., Muenter, M. D., Aronson, A., Kurland, L. T., and Melton, L. J., (1988). Epidemiology of focal and generalized dystonia in Rochester, Minnesota. Mov. Disord. 3, 188-194. doi: 10.1002/mds.8700 30302
    • (1988) Mov. Disord , vol.3 , pp. 188-194
    • Nutt, J.G.1    Muenter, M.D.2    Aronson, A.3    Kurland, L.T.4    Melton, L.J.5
  • 109
    • 62849086589 scopus 로고    scopus 로고
    • Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort
    • doi: 10.1038/mp.2008.122
    • Ollila, H. M., Soronen, P., Silander, K., Palo, O. M., Kieseppa, T., Kaunisto, M. A., et al. (2009). Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. Mol. Psychiatry 14, 351-353. doi: 10.1038/mp.2008.122
    • (2009) Mol. Psychiatry , vol.14 , pp. 351-353
    • Ollila, H.M.1    Soronen, P.2    Silander, K.3    Palo, O.M.4    Kieseppa, T.5    Kaunisto, M.A.6
  • 110
    • 0033366538 scopus 로고    scopus 로고
    • Inhalational anesthetics activate two-pore-domain background K+ channels
    • doi: 10.1038/8084
    • Patel, A. J., Honore, E., Lesage, F., Fink, M., Romey, G., and Lazdunski, M. (1999). Inhalational anesthetics activate two-pore-domain background K+ channels. Nat. Neurosci. 2, 422-426. doi: 10.1038/8084
    • (1999) Nat. Neurosci , vol.2 , pp. 422-426
    • Patel, A.J.1    Honore, E.2    Lesage, F.3    Fink, M.4    Romey, G.5    Lazdunski, M.6
  • 111
    • 84863793247 scopus 로고    scopus 로고
    • Cysteine-rich domains related to Frizzled receptors and Hedgehog-interacting proteins
    • doi: 10.1002/pro.2105
    • Pei, J., and Grishin, N. V. (2012). Cysteine-rich domains related to Frizzled receptors and Hedgehog-interacting proteins. Protein Sci. 21, 1172-1184. doi: 10.1002/pro.2105
    • (2012) Protein Sci , vol.21 , pp. 1172-1184
    • Pei, J.1    Grishin, N.V.2
  • 112
    • 58549113981 scopus 로고    scopus 로고
    • Genetic analysis of crawling and swimming locomotory pat- terns in C. elegans
    • doi: 10.1073/pnas.0810359105
    • Pierce-Shimomura, J. T., Chen, B. L., Mun, J. J., Ho, R., Sarkis, R., and McIntire, S. L. (2008). Genetic analysis of crawling and swimming locomotory pat- terns in C. elegans. Proc. Natl. Acad. Sci. U.S.A. 105, 20982-20987. doi: 10.1073/pnas.0810359105
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 20982-20987
    • Pierce-Shimomura, J.T.1    Chen, B.L.2    Mun, J.J.3    Ho, R.4    Sarkis, R.5    McIntire, S.L.6
  • 113
    • 64849101288 scopus 로고    scopus 로고
    • Raphe neurons stimulate respiratory circuit activity by multiple mech- anisms via endogenously released serotonin and substance P
    • doi: 10.1523/JNEUROSCI.5271-08.2009
    • Ptak, K., Yamanishi, T., Aungst, J., Milescu, L. S., Zhang, R., Richerson, G. B., et al. (2009). Raphe neurons stimulate respiratory circuit activity by multiple mech- anisms via endogenously released serotonin and substance P. J. Neurosci. 29, 3720-3737. doi: 10.1523/JNEUROSCI.5271-08.2009
    • (2009) J. Neurosci , vol.29 , pp. 3720-3737
    • Ptak, K.1    Yamanishi, T.2    Aungst, J.3    Milescu, L.S.4    Zhang, R.5    Richerson, G.B.6
  • 114
    • 58149119492 scopus 로고    scopus 로고
    • Twelve new patients with 13q deletion syndrome: Genotype-phenotype analyses in progress
    • doi: 10.1016/j.ejmg.2008.10.002
    • Quelin, C., Bendavid, C., Dubourg, C., De La Rochebrochard, C., Lucas, J., Henry, C., et al. (2009). Twelve new patients with 13q deletion syndrome: genotype-phenotype analyses in progress. Eur. J. Med. Genet. 52, 41-46. doi: 10.1016/j.ejmg.2008.10.002
    • (2009) Eur. J. Med. Genet , vol.52 , pp. 41-46
    • Quelin, C.1    Bendavid, C.2    Dubourg, C.3    de la Rochebrochard, C.4    Lucas, J.5    Henry, C.6
  • 115
    • 0032736428 scopus 로고    scopus 로고
    • A stom- atin and a degenerin interact to control anesthetic sensitivity in Caenorhabditis elegans
    • Rajaram, S., Spangler, T. L., Sedensky, M. M., and Morgan, P. G. (1999). A stom- atin and a degenerin interact to control anesthetic sensitivity in Caenorhabditis elegans. Genetics 153, 1673-1682.
    • (1999) Genetics , vol.153 , pp. 1673-1682
    • Rajaram, S.1    Spangler, T.L.2    Sedensky, M.M.3    Morgan, P.G.4
  • 116
    • 77955289156 scopus 로고    scopus 로고
    • A locus for juvenile myoclonic epilepsy maps to 2q33-q36
    • doi: 10.1007/s00439-010-0831-6
    • Ratnapriya, R., Vijai, J., Kadandale, J. S., Iyer, R. S., Radhakrishnan, K., and Anand, A. (2010). A locus for juvenile myoclonic epilepsy maps to 2q33-q36. Hum. Genet. 128, 123-130. doi: 10.1007/s00439-010-0831-6
    • (2010) Hum. Genet , vol.128 , pp. 123-130
    • Ratnapriya, R.1    Vijai, J.2    Kadandale, J.S.3    Iyer, R.S.4    Radhakrishnan, K.5    Anand, A.6
  • 117
    • 84155183310 scopus 로고    scopus 로고
    • Sodium leak channels in neuronal excitability and rhythmic behaviors
    • doi: 10.1016/j.neuron.2011.12.007
    • Ren, D. (2011). Sodium leak channels in neuronal excitability and rhythmic behaviors. Neuron 72, 899-911. doi: 10.1016/j.neuron.2011.12.007
    • (2011) Neuron , vol.72 , pp. 899-911
    • Ren, D.1
  • 118
    • 84873670723 scopus 로고    scopus 로고
    • Regulation of insulin secretion in human pancreatic islets
    • doi: 10.1146/annurev-physiol- 030212-183754
    • Rorsman, P., and Braun, M. (2013). Regulation of insulin secretion in human pancreatic islets. Annu. Rev. Physiol. 75, 155-179. doi: 10.1146/annurev-physiol- 030212-183754
    • (2013) Annu. Rev. Physiol , vol.75 , pp. 155-179
    • Rorsman, P.1    Braun, M.2
  • 119
    • 84876859781 scopus 로고    scopus 로고
    • Dogma derailed: The many influences of RNA on the genome
    • doi: 10.1016/j.molcel.2013.02.010
    • Sabin, L. R., Delas, M. J., and Hannon, G. J. (2013). Dogma derailed: the many influences of RNA on the genome. Mol. Cell 49, 783-794. doi: 10.1016/j.molcel.2013.02.010
    • (2013) Mol. Cell , vol.49 , pp. 783-794
    • Sabin, L.R.1    Delas, M.J.2    Hannon, G.J.3
  • 120
    • 0037398465 scopus 로고    scopus 로고
    • The epidemiology of epilepsy revisited
    • doi: 10.1097/01.wco.0000063766.15877.8e
    • Sander, J. W. (2003). The epidemiology of epilepsy revisited. Curr. Opin. Neurol. 16, 165-170. doi: 10.1097/01.wco.0000063766.15877.8e
    • (2003) Curr. Opin. Neurol , vol.16 , pp. 165-170
    • Sander, J.W.1
  • 121
    • 79953206567 scopus 로고    scopus 로고
    • Regulation of sodium channel activity by phosphorylation
    • doi: 10.1016/j.semcdb.2010.10.002
    • Scheuer, T. (2011). Regulation of sodium channel activity by phosphorylation. Semin. Cell Dev. Biol. 22, 160-165. doi: 10.1016/j.semcdb.2010.10.002
    • (2011) Semin. Cell Dev. Biol , vol.22 , pp. 160-165
    • Scheuer, T.1
  • 122
    • 0035099138 scopus 로고    scopus 로고
    • A genome-wide search for genes that relate to a low level of response to alcohol
    • doi: 10.1111/j.1530- 0277.2001.tb02217
    • Schuckit, M. A., Edenberg, H. J., Kalmijn, J., Flury, L., Smith, T. L., Reich, T., et al. (2001). A genome-wide search for genes that relate to a low level of response to alcohol. Alcohol. Clin. Exp. Res. 25, 323-329. doi: 10.1111/j.1530- 0277.2001.tb02217
    • (2001) Alcohol. Clin. Exp. Res , vol.25 , pp. 323-329
    • Schuckit, M.A.1    Edenberg, H.J.2    Kalmijn, J.3    Flury, L.4    Smith, T.L.5    Reich, T.6
  • 123
    • 0242691247 scopus 로고    scopus 로고
    • Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22
    • doi: 10.1086/379083
    • Scott, W. K., Hauser, E. R., Schmechel, D. E., Welsh-Bohmer, K. A., Small, G. W., Roses, A. D., et al. (2003). Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22. Am. J. Hum. Genet. 73, 1041-1051. doi: 10.1086/379083
    • (2003) Am. J. Hum. Genet , vol.73 , pp. 1041-1051
    • Scott, W.K.1    Hauser, E.R.2    Schmechel, D.E.3    Welsh-Bohmer, K.A.4    Small, G.W.5    Roses, A.D.6
  • 124
    • 0023225863 scopus 로고
    • Genetic analysis of halothane sensitivity in Caenorhabditis elegans
    • doi: 10.1126/sci- ence.3576211
    • Sedensky, M. M., and Meneely, P. M. (1987). Genetic analysis of halothane sensitivity in Caenorhabditis elegans. Science 236, 952-954. doi: 10.1126/sci- ence.3576211
    • (1987) Science , vol.236 , pp. 952-954
    • Sedensky, M.M.1    Meneely, P.M.2
  • 125
    • 0035041474 scopus 로고    scopus 로고
    • Model organisms: New insights into ion channel and transporter function. Stomatin homo- logues interact in Caenorhabditis elegans
    • Sedensky, M. M., Siefker, J. M., and Morgan, P. G. (2001). Model organisms: new insights into ion channel and transporter function. Stomatin homo- logues interact in Caenorhabditis elegans. Am. J. Physiol. Cell Physiol. 280, C1340-C1348.
    • (2001) Am. J. Physiol. Cell Physiol , vol.280
    • Sedensky, M.M.1    Siefker, J.M.2    Morgan, P.G.3
  • 126
    • 84873804456 scopus 로고    scopus 로고
    • NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels
    • doi: 10.1371/jour- nal.pone.0055088
    • Senatore, A., Monteil, A., Van Minnen, J., Smit, A. B., and Spafford, J. D. (2013). NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels. PLoS ONE 8:e55088. doi: 10.1371/jour- nal.pone.0055088
    • (2013) PLoS ONE , vol.8
    • Senatore, A.1    Monteil, A.2    van Minnen, J.3    Smit, A.B.4    Spafford, J.D.5
  • 127
    • 84876551918 scopus 로고    scopus 로고
    • A uniquely adaptable pore is consis- tent with NALCN being an ion sensor
    • doi: 10.4161/chan.23981
    • Senatore, A., and Spafford, J. D. (2013). A uniquely adaptable pore is consis- tent with NALCN being an ion sensor. Channels (Austin). 7, 60-68. doi: 10.4161/chan.23981
    • (2013) Channels (Austin) , vol.7 , pp. 60-68
    • Senatore, A.1    Spafford, J.D.2
  • 128
    • 0036944069 scopus 로고    scopus 로고
    • Dysmorphic face in two siblings with infantile neuroaxonal dystrophy
    • Seven, M., Ozkilic, A., and Yuksel, A. (2002). Dysmorphic face in two siblings with infantile neuroaxonal dystrophy. Genet. Couns. 13, 465-473.
    • (2002) Genet. Couns , vol.13 , pp. 465-473
    • Seven, M.1    Ozkilic, A.2    Yuksel, A.3
  • 129
    • 70349934573 scopus 로고    scopus 로고
    • The role of peptides in central sensitization
    • doi: 10.1007/978-3-540-79090-7_13
    • Seybold, V. S. (2009). The role of peptides in central sensitization. Handb. Exp. Pharmacol. 451-491. doi: 10.1007/978-3-540-79090-7_13
    • (2009) Handb. Exp. Pharmacol , pp. 451-491
    • Seybold, V.S.1
  • 130
    • 84893319241 scopus 로고    scopus 로고
    • A review of the pathophysiology, etiol- ogy, and treatment of attention-deficit hyperactivity disorder (ADHD)
    • doi: 10.1177/1060028013510699
    • Sharma, A., and Couture, J. (2014). A review of the pathophysiology, etiol- ogy, and treatment of attention-deficit hyperactivity disorder (ADHD). Ann. Pharmacother. 48, 209-225. doi: 10.1177/1060028013510699
    • (2014) Ann. Pharmacother , vol.48 , pp. 209-225
    • Sharma, A.1    Couture, J.2
  • 131
    • 84870878516 scopus 로고    scopus 로고
    • More than one century of schizophrenia: An evolving perspective
    • doi: 10.1097/NMD.0b013e318275d249
    • Silveira, C., Marques-Teixeira, J., and De Bastos-Leite, A. J. (2012). More than one century of schizophrenia: an evolving perspective. J. Nerv. Ment. Dis. 200, 1054-1057. doi: 10.1097/NMD.0b013e318275d249
    • (2012) J. Nerv. Ment. Dis , vol.200 , pp. 1054-1057
    • Silveira, C.1    Marques-Teixeira, J.2    De Bastos-Leite, A.J.3
  • 132
    • 79955745745 scopus 로고    scopus 로고
    • Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation
    • doi: 10.1152/physiolgenomics.00188.2010
    • Sinke, A. P., Caputo, C., Tsaih, S. W., Yuan, R., Ren, D., Deen, P. M., et al. (2011). Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol. Genomics 43, 265-270. doi: 10.1152/physiolgenomics.00188.2010
    • (2011) Physiol. Genomics , vol.43 , pp. 265-270
    • Sinke, A.P.1    Caputo, C.2    Tsaih, S.W.3    Yuan, R.4    Ren, D.5    Deen, P.M.6
  • 133
    • 0030749226 scopus 로고    scopus 로고
    • Regulation of excitatory and inhibitory neurotransmitter-gated ion channels by protein phosphorylation
    • doi: 10.1016/S0959-4388(97)80063-3
    • Smart, T. G. (1997). Regulation of excitatory and inhibitory neurotransmitter-gated ion channels by protein phosphorylation. Curr. Opin. Neurobiol. 7, 358-367. doi: 10.1016/S0959-4388(97)80063-3
    • (1997) Curr. Opin. Neurobiol , vol.7 , pp. 358-367
    • Smart, T.G.1
  • 134
    • 84861143628 scopus 로고    scopus 로고
    • Bipolar disorder
    • doi: 10.1016/B978-0-444-52002-9.00015-2
    • Smith, D. J., Whitham, E. A., and Ghaemi, S. N. (2012). Bipolar disorder. Handb. Clin. Neurol. 106, 251-263. doi: 10.1016/B978-0-444-52002-9.00015-2
    • (2012) Handb. Clin. Neurol , vol.106 , pp. 251-263
    • Smith, D.J.1    Whitham, E.A.2    Ghaemi, S.N.3
  • 135
    • 34248562076 scopus 로고    scopus 로고
    • The sodium "leak" has finally been plugged
    • doi: 10.1016/j.neuron.2007.05.005
    • Snutch, T. P., and Monteil, A. (2007). The sodium "leak" has finally been plugged. Neuron 54, 505-507. doi: 10.1016/j.neuron.2007.05.005
    • (2007) Neuron , vol.54 , pp. 505-507
    • Snutch, T.P.1    Monteil, A.2
  • 136
    • 79251594640 scopus 로고    scopus 로고
    • Lack of association of NALCN genetic variants with schizophrenia
    • doi: 10.1016/j.psychres.2010.07.009
    • Souza, R. P., Rosa, D. V., Romano-Silva, M. A., Zhen, M., Meltzer, H. Y., Lieberman, J. A., et al. (2011). Lack of association of NALCN genetic variants with schizophrenia. Psychiatry Res. 185, 450-452. doi: 10.1016/j.psychres.2010.07.009
    • (2011) Psychiatry Res , vol.185 , pp. 450-452
    • Souza, R.P.1    Rosa, D.V.2    Romano-Silva, M.A.3    Zhen, M.4    Meltzer, H.Y.5    Lieberman, J.A.6
  • 137
    • 77957337125 scopus 로고    scopus 로고
    • Conserved role of unc-79 in ethanol responses in lightweight mutant mice
    • doi: 10.1371/jour- nal.pgen.1001057
    • Speca, D. J., Chihara, D., Ashique, A. M., Bowers, M. S., Pierce-Shimomura, J. T., Lee, J., et al. (2010). Conserved role of unc-79 in ethanol responses in lightweight mutant mice. PLoS Genet. 6:1057. doi: 10.1371/jour- nal.pgen.1001057
    • (2010) PLoS Genet , vol.6 , pp. 1057
    • Speca, D.J.1    Chihara, D.2    Ashique, A.M.3    Bowers, M.S.4    Pierce-Shimomura, J.T.5    Lee, J.6
  • 138
    • 13844255273 scopus 로고    scopus 로고
    • Molecular biology and genetics of Alzheimer's disease
    • doi: 10.1016/j.crvi.2004.10.013
    • St George-Hyslop, P. H., and Petit, A. (2005). Molecular biology and genetics of Alzheimer's disease. C. R. Biol. 328, 119-130. doi: 10.1016/j.crvi.2004.10.013
    • (2005) C. R. Biol , vol.328 , pp. 119-130
    • St George-Hyslop, P.H.1    Petit, A.2
  • 139
    • 0038579335 scopus 로고    scopus 로고
    • Periodic breathing and genetics
    • doi: 10.1016/S1569-9048(03)00036-3
    • Strohl, K. P. (2003). Periodic breathing and genetics. Respir. Physiol. Neurobiol. 135, 179-185. doi: 10.1016/S1569-9048(03)00036-3
    • (2003) Respir. Physiol. Neurobiol , vol.135 , pp. 179-185
    • Strohl, K.P.1
  • 140
    • 0037144072 scopus 로고    scopus 로고
    • Dorsal horn-enriched genes identified by DNA microarray, in situ hybridiza- tion and immunohistochemistry
    • doi: 10.1186/1471- 2202-3-11
    • Sun, H., Xu, J., Della Penna, K. B., Benz, R. J., Kinose, F., Holder, D. J., et al. (2002). Dorsal horn-enriched genes identified by DNA microarray, in situ hybridiza- tion and immunohistochemistry. BMC Neurosci. 3:11. doi: 10.1186/1471- 2202-3-11
    • (2002) BMC Neurosci , vol.3 , pp. 11
    • Sun, H.1    Xu, J.2    della Penna, K.B.3    Benz, R.J.4    Kinose, F.5    Holder, D.J.6
  • 141
    • 77953385525 scopus 로고    scopus 로고
    • The NALCN ion channel is a new actor in pancreatic beta-cell physiology
    • doi: 10.4161/isl.2.1.10522
    • Swayne, L. A., Mezghrani, A., Lory, P., Nargeot, J., and Monteil, A. (2010). The NALCN ion channel is a new actor in pancreatic beta-cell physiology. Islets 2, 54-56. doi: 10.4161/isl.2.1.10522
    • (2010) Islets , vol.2 , pp. 54-56
    • Swayne, L.A.1    Mezghrani, A.2    Lory, P.3    Nargeot, J.4    Monteil, A.5
  • 142
    • 68249089016 scopus 로고    scopus 로고
    • The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line
    • doi: 10.1038/embor.2009.125
    • Swayne, L. A., Mezghrani, A., Varrault, A., Chemin, J., Bertrand, G., Dalle, S., et al. (2009). The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line. EMBO Rep. 10, 873-880. doi: 10.1038/embor.2009.125
    • (2009) EMBO Rep , vol.10 , pp. 873-880
    • Swayne, L.A.1    Mezghrani, A.2    Varrault, A.3    Chemin, J.4    Bertrand, G.5    Dalle, S.6
  • 143
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's dis- ease amyloid hypothesis: A genetic perspective
    • doi: 10.1016/j.cell.2005.02.008
    • Tanzi, R. E., and Bertram, L. (2005). Twenty years of the Alzheimer's dis- ease amyloid hypothesis: a genetic perspective. Cell 120, 545-555. doi: 10.1016/j.cell.2005.02.008
    • (2005) Cell , vol.120 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 144
    • 84867562644 scopus 로고    scopus 로고
    • Analysis of treatment-resistant schizophrenia and 384 mark- ers from candidate genes
    • doi: 10.1097/FPC.0b013e3283586c04
    • Teo, C., Zai, C., Borlido, C., Tomasetti, C., Strauss, J., Shinkai, T., et al. (2012). Analysis of treatment-resistant schizophrenia and 384 mark- ers from candidate genes. Pharmacogenet. Genomics 22, 807-811. doi: 10.1097/FPC.0b013e3283586c04
    • (2012) Pharmacogenet. Genomics , vol.22 , pp. 807-811
    • Teo, C.1    Zai, C.2    Borlido, C.3    Tomasetti, C.4    Strauss, J.5    Shinkai, T.6
  • 145
    • 77957914573 scopus 로고    scopus 로고
    • Genome-wide association scan of trait depression
    • doi: 10.1016/j.biopsych.2010.06.030
    • Terracciano, A., Tanaka, T., Sutin, A. R., Sanna, S., Deiana, B., Lai, S., et al. (2010). Genome-wide association scan of trait depression. Biol. Psychiatry 68, 811-817. doi: 10.1016/j.biopsych.2010.06.030
    • (2010) Biol. Psychiatry , vol.68 , pp. 811-817
    • Terracciano, A.1    Tanaka, T.2    Sutin, A.R.3    Sanna, S.4    Deiana, B.5    Lai, S.6
  • 146
    • 84898246321 scopus 로고    scopus 로고
    • Aggregation formation in the polyglutamine diseases: Protection at a cost?
    • doi: 10.1007/s10059-013- 0167-x
    • Todd, T. W., and Lim, J. (2013). Aggregation formation in the polyglutamine diseases: protection at a cost? Mol. Cells 36, 185-194. doi: 10.1007/s10059-013- 0167-x
    • (2013) Mol. Cells , vol.36 , pp. 185-194
    • Todd, T.W.1    Lim, J.2
  • 147
    • 84902486234 scopus 로고    scopus 로고
    • Major depressive disorder in Dsm-5: Implications for clinical practice and research of changes from Dsm- Iv
    • doi: 10.1002/da.22217. [Epub ahead of print]
    • Uher, R., Payne, J. L., Pavlova, B., and Perlis, R. H. (2013). Major depressive disorder in Dsm-5: implications for clinical practice and research of changes from Dsm- Iv. Depress. Anxiety. doi: 10.1002/da.22217. [Epub ahead of print]
    • (2013) Depress. Anxiety
    • Uher, R.1    Payne, J.L.2    Pavlova, B.3    Perlis, R.H.4
  • 148
    • 80054717695 scopus 로고    scopus 로고
    • Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels
    • doi: 10.1007/s00424-011- 1004-8
    • Vacher, H., and Trimmer, J. S. (2011). Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels. Pflugers Arch. 462, 631-643. doi: 10.1007/s00424-011- 1004-8
    • (2011) Pflugers Arch , vol.462 , pp. 631-643
    • Vacher, H.1    Trimmer, J.S.2
  • 149
    • 33748926439 scopus 로고    scopus 로고
    • A succession of anesthetic endpoints in the Drosophila brain
    • doi: 10.1002/neu.20300
    • Van Swinderen, B. (2006). A succession of anesthetic endpoints in the Drosophila brain. J. Neurobiol. 66, 1195-1211. doi: 10.1002/neu.20300
    • (2006) J. Neurobiol , vol.66 , pp. 1195-1211
    • van Swinderen, B.1
  • 150
    • 38949205714 scopus 로고    scopus 로고
    • Chromosome deletions in 13q33-34: Report of four patients and review of the literature
    • doi: 10.1002/ajmg.a.32127
    • Walczak-Sztulpa, J., Wisniewska, M., Latos-Bielenska, A., Linne, M., Kelbova, C., Belitz, B., et al. (2008). Chromosome deletions in 13q33-34: report of four patients and review of the literature. Am. J. Med. Genet. A 146, 337-342. doi: 10.1002/ajmg.a.32127
    • (2008) Am. J. Med. Genet. A , vol.146 , pp. 337-342
    • Walczak-Sztulpa, J.1    Wisniewska, M.2    Latos-Bielenska, A.3    Linne, M.4    Kelbova, C.5    Belitz, B.6
  • 151
    • 67649312081 scopus 로고    scopus 로고
    • UNC80 functions as a scaffold for Src kinases in NALCN channel function
    • doi: 10.4161/chan.3.3.8853
    • Wang, H., and Ren, D. (2009). UNC80 functions as a scaffold for Src kinases in NALCN channel function. Channels (Austin). 3, 161-163. doi: 10.4161/chan.3.3.8853
    • (2009) Channels (Austin) , vol.3 , pp. 161-163
    • Wang, H.1    Ren, D.2
  • 152
    • 78249259373 scopus 로고    scopus 로고
    • A genome-wide meta-analysis iden- tifies novel loci associated with schizophrenia and bipolar disorder
    • doi: 10.1016/j.schres.2010.09.002
    • Wang, K. S., Liu, X. F., and Aragam, N. (2010). A genome-wide meta-analysis iden- tifies novel loci associated with schizophrenia and bipolar disorder. Schizophr. Res. 124, 192-199. doi: 10.1016/j.schres.2010.09.002
    • (2010) Schizophr. Res , vol.124 , pp. 192-199
    • Wang, K.S.1    Liu, X.F.2    Aragam, N.3
  • 153
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control, C, doi: 10.1038/nature05911
    • Wellcome Trust Case Control, C. (2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678. doi: 10.1038/nature05911
    • (2007) Nature , vol.447 , pp. 661-678
  • 154
    • 84893677369 scopus 로고    scopus 로고
    • Family-based association analysis of alcohol dependence criteria and severity
    • doi: 10.1111/acer. 12251
    • Wetherill, L., Kapoor, M., Agrawal, A., Bucholz, K., Koller, D., Bertelsen, S. E., et al. (2014). Family-based association analysis of alcohol dependence criteria and severity. Alcohol. Clin. Exp. Res. 38, 354-366. doi: 10.1111/acer. 12251
    • (2014) Alcohol. Clin. Exp. Res , vol.38 , pp. 354-366
    • Wetherill, L.1    Kapoor, M.2    Agrawal, A.3    Bucholz, K.4    Koller, D.5    Bertelsen, S.E.6
  • 155
    • 78549278120 scopus 로고    scopus 로고
    • Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory com- plexes
    • doi: 10.1186/1471-2164-11-654
    • Whan, V., Hobbs, M., McWilliam, S., Lynn, D. J., Lutzow, Y. S., Khatkar, M., et al. (2010). Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory com- plexes. BMC Genomics 11:654. doi: 10.1186/1471-2164-11-654
    • (2010) BMC Genomics , vol.11 , pp. 654
    • Whan, V.1    Hobbs, M.2    McWilliam, S.3    Lynn, D.J.4    Lutzow, Y.S.5    Khatkar, M.6
  • 156
    • 84883780132 scopus 로고    scopus 로고
    • Sensory symptoms in restless legs syndrome: The enigma of pain
    • doi: 10.1016/j.sleep.2013.05.017
    • Winkelman, J. W., Gagnon, A., and Clair, A. G. (2013). Sensory symptoms in restless legs syndrome: the enigma of pain. Sleep Med. 14, 934-942. doi: 10.1016/j.sleep.2013.05.017
    • (2013) Sleep Med , vol.14 , pp. 934-942
    • Winkelman, J.W.1    Gagnon, A.2    Clair, A.G.3
  • 157
    • 84875509376 scopus 로고    scopus 로고
    • NLF-1 delivers a sodium leak channel to regulate neuronal excitability and modulate rhythmic locomotion
    • doi: 10.1016/j.neuron.2013.01.018
    • Xie, L., Gao, S., Alcaire, S. M., Aoyagi, K., Wang, Y., Griffin, J. K., et al. (2013). NLF-1 delivers a sodium leak channel to regulate neuronal excitability and modulate rhythmic locomotion. Neuron 77, 1069-1082. doi: 10.1016/j.neuron.2013.01.018
    • (2013) Neuron , vol.77 , pp. 1069-1082
    • Xie, L.1    Gao, S.2    Alcaire, S.M.3    Aoyagi, K.4    Wang, Y.5    Griffin, J.K.6
  • 158
    • 76249083839 scopus 로고    scopus 로고
    • NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD
    • doi: 10.1177/0269881108100255
    • Yan, T. C., McQuillin, A., Thapar, A., Asherson, P., Hunt, S. P., Stanford, S. C., et al. (2010). NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD. J. Psychopharmacol. 24, 27-38. doi: 10.1177/0269881108100255
    • (2010) J. Psychopharmacol , vol.24 , pp. 27-38
    • Yan, T.C.1    McQuillin, A.2    Thapar, A.3    Asherson, P.4    Hunt, S.P.5    Stanford, S.C.6
  • 159
    • 41749099430 scopus 로고    scopus 로고
    • A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans
    • doi: 10.1371/journal.pbio. 0060055
    • Yeh, E., Ng, S., Zhang, M., Bouhours, M., Wang, Y., Wang, M., et al. (2008). A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans. PLoS Biol. 6:e55. doi: 10.1371/journal.pbio. 0060055
    • (2008) PLoS Biol , vol.e55 , pp. 6
    • Yeh, E.1    Ng, S.2    Zhang, M.3    Bouhours, M.4    Wang, Y.5    Wang, M.6
  • 160
    • 84890099110 scopus 로고    scopus 로고
    • Progress and future aspects in genetics of human hypertension
    • doi: 10.1007/s11906-013-0388-6
    • Zhao, Q., Kelly, T. N., Li, C., and He, J. (2013). Progress and future aspects in genetics of human hypertension. Curr. Hypertens. Rep. 15, 676-686. doi: 10.1007/s11906-013-0388-6
    • (2013) Curr. Hypertens. Rep , vol.15 , pp. 676-686
    • Zhao, Q.1    Kelly, T.N.2    Li, C.3    He, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.